Rattus norvegicus

0 known processes

Tiparp

TCDD-inducible poly(ADP-ribose) polymerase

Tiparp biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
regulation of apoptotic process GO:0042981 335 0.165
cellular response to endogenous stimulus GO:0071495 377 0.127
apoptotic process GO:0006915 381 0.121
response to camp GO:0051591 91 0.094
regulation of molecular function GO:0065009 398 0.089
negative regulation of apoptotic process GO:0043066 181 0.088
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.085
programmed cell death GO:0012501 392 0.075
response to hydrogen peroxide GO:0042542 89 0.074
carbohydrate derivative metabolic process GO:1901135 346 0.074
transcription from rna polymerase ii promoter GO:0006366 252 0.074
positive regulation of cellular biosynthetic process GO:0031328 295 0.074
regulation of programmed cell death GO:0043067 341 0.072
cellular response to oxygen containing compound GO:1901701 386 0.067
nucleic acid templated transcription GO:0097659 379 0.060
regulation of nucleic acid templated transcription GO:1903506 380 0.059
negative regulation of nucleic acid templated transcription GO:1903507 117 0.059
regulation of rna metabolic process GO:0051252 391 0.058
negative regulation of biosynthetic process GO:0009890 168 0.058
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.056
negative regulation of macromolecule metabolic process GO:0010605 260 0.055
regulation of phosphorylation GO:0042325 248 0.053
response to inorganic substance GO:0010035 377 0.052
cellular ketone metabolic process GO:0042180 51 0.050
response to estrogen GO:0043627 232 0.049
regulation of catalytic activity GO:0050790 304 0.049
response to growth factor GO:0070848 189 0.047
regulation of rna biosynthetic process GO:2001141 381 0.047
cellular response to fluid shear stress GO:0071498 4 0.047
reproductive process GO:0022414 372 0.047
oxoacid metabolic process GO:0043436 290 0.047
negative regulation of molecular function GO:0044092 133 0.046
cellular component biogenesis GO:0044085 368 0.045
cellular component assembly GO:0022607 360 0.045
positive regulation of transcription dna templated GO:0045893 197 0.044
positive regulation of gene expression GO:0010628 244 0.044
protein phosphorylation GO:0006468 345 0.043
macromolecular complex subunit organization GO:0043933 339 0.042
organophosphate metabolic process GO:0019637 370 0.042
cellular response to hormone stimulus GO:0032870 247 0.042
transcription dna templated GO:0006351 377 0.042
response to hypoxia GO:0001666 231 0.042
negative regulation of programmed cell death GO:0043069 183 0.042
cellular response to growth factor stimulus GO:0071363 162 0.041
negative regulation of cell death GO:0060548 229 0.041
single organism biosynthetic process GO:0044711 342 0.040
regulation of multicellular organismal development GO:2000026 376 0.040
rna metabolic process GO:0016070 406 0.040
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.039
positive regulation of nucleic acid templated transcription GO:1903508 197 0.039
macromolecular complex assembly GO:0065003 273 0.039
regulation of cellular ketone metabolic process GO:0010565 27 0.038
protein complex assembly GO:0006461 263 0.038
regulation of protein metabolic process GO:0051246 289 0.038
regulation of cellular protein metabolic process GO:0032268 267 0.036
regulation of cell differentiation GO:0045595 320 0.036
positive regulation of developmental process GO:0051094 283 0.036
response to oxidative stress GO:0006979 186 0.035
carboxylic acid metabolic process GO:0019752 289 0.035
intracellular signal transduction GO:0035556 314 0.035
single organism reproductive process GO:0044702 297 0.034
response to organophosphorus GO:0046683 102 0.034
response to decreased oxygen levels GO:0036293 237 0.034
negative regulation of metabolic process GO:0009892 331 0.033
cell projection organization GO:0030030 302 0.033
protein complex biogenesis GO:0070271 263 0.033
regulation of signal transduction GO:0009966 318 0.033
positive regulation of rna biosynthetic process GO:1902680 197 0.033
regulation of transferase activity GO:0051338 123 0.033
regulation of phosphate metabolic process GO:0019220 349 0.032
positive regulation of biosynthetic process GO:0009891 319 0.032
anatomical structure morphogenesis GO:0009653 298 0.032
response to oxygen levels GO:0070482 265 0.032
response to cytokine GO:0034097 215 0.031
negative regulation of cellular biosynthetic process GO:0031327 161 0.031
nucleoside metabolic process GO:0009116 179 0.031
neuron differentiation GO:0030182 368 0.030
lipid metabolic process GO:0006629 283 0.030
neurological system process GO:0050877 219 0.030
negative regulation of gene expression GO:0010629 199 0.030
response to purine containing compound GO:0014074 126 0.030
regulation of transcription dna templated GO:0006355 374 0.030
positive regulation of multicellular organismal process GO:0051240 387 0.029
cellular response to organic cyclic compound GO:0071407 202 0.029
regulation of cell development GO:0060284 263 0.029
protein heterooligomerization GO:0051291 89 0.029
response to radiation GO:0009314 137 0.029
negative regulation of signaling GO:0023057 157 0.029
response to estradiol GO:0032355 164 0.029
positive regulation of molecular function GO:0044093 230 0.028
multicellular organismal reproductive process GO:0048609 233 0.028
response to acid chemical GO:0001101 222 0.028
cellular amino acid metabolic process GO:0006520 107 0.028
positive regulation of cell death GO:0010942 184 0.027
protein complex subunit organization GO:0071822 302 0.027
negative regulation of rna metabolic process GO:0051253 123 0.027
positive regulation of cell differentiation GO:0045597 217 0.027
negative regulation of cellular metabolic process GO:0031324 281 0.027
purine containing compound metabolic process GO:0072521 253 0.027
cellular amine metabolic process GO:0044106 38 0.027
regulation of cellular amino acid metabolic process GO:0006521 2 0.026
regulation of cellular amine metabolic process GO:0033238 8 0.026
protein oligomerization GO:0051259 191 0.026
ribose phosphate metabolic process GO:0019693 235 0.026
nucleobase containing small molecule metabolic process GO:0055086 316 0.026
negative regulation of protein metabolic process GO:0051248 114 0.025
response to reactive oxygen species GO:0000302 120 0.025
amine metabolic process GO:0009308 38 0.025
regulation of cellular localization GO:0060341 263 0.024
cellular response to lipid GO:0071396 201 0.024
homeostatic process GO:0042592 331 0.024
synaptic transmission GO:0007268 235 0.024
catabolic process GO:0009056 351 0.024
establishment of protein localization GO:0045184 141 0.023
regulation of protein modification process GO:0031399 194 0.023
multi organism reproductive process GO:0044703 262 0.023
regulation of cell projection organization GO:0031344 175 0.023
regulation of phosphorus metabolic process GO:0051174 349 0.023
multicellular organism reproduction GO:0032504 233 0.023
purine ribonucleotide metabolic process GO:0009150 227 0.023
cellular response to nitrogen compound GO:1901699 210 0.023
cellular response to stress GO:0033554 269 0.022
response to glucocorticoid GO:0051384 223 0.022
anterior posterior pattern specification GO:0009952 1 0.022
response to extracellular stimulus GO:0009991 380 0.022
nucleotide metabolic process GO:0009117 279 0.021
regulation of protein phosphorylation GO:0001932 183 0.021
organic substance catabolic process GO:1901575 316 0.021
response to ketone GO:1901654 182 0.021
response to peptide GO:1901652 292 0.021
peptide biosynthetic process GO:0043043 3 0.021
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.021
neuron apoptotic process GO:0051402 88 0.021
organic acid metabolic process GO:0006082 292 0.021
developmental process involved in reproduction GO:0003006 159 0.020
neuron development GO:0048666 286 0.020
cation transport GO:0006812 382 0.020
rhythmic process GO:0048511 156 0.020
nucleoside phosphate metabolic process GO:0006753 283 0.020
negative regulation of response to stimulus GO:0048585 155 0.020
positive regulation of rna metabolic process GO:0051254 203 0.019
negative regulation of cell communication GO:0010648 158 0.019
glycosyl compound metabolic process GO:1901657 182 0.019
blood circulation GO:0008015 183 0.019
cardiovascular system development GO:0072358 134 0.019
neuron death GO:0070997 127 0.019
cellular response to organonitrogen compound GO:0071417 197 0.018
smooth muscle cell proliferation GO:0048659 77 0.018
localization of cell GO:0051674 202 0.018
positive regulation of cell proliferation GO:0008284 249 0.018
negative regulation of cellular protein metabolic process GO:0032269 106 0.018
purine nucleotide catabolic process GO:0006195 136 0.018
regulation of cell proliferation GO:0042127 359 0.017
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.017
circadian rhythm GO:0007623 88 0.017
enzyme linked receptor protein signaling pathway GO:0007167 116 0.017
circulatory system process GO:0003013 183 0.017
regulation of mapk cascade GO:0043408 116 0.017
transforming growth factor beta3 production GO:0032907 2 0.017
metal ion transport GO:0030001 289 0.017
regulation of neurogenesis GO:0050767 247 0.016
cell cell signaling GO:0007267 335 0.016
regulation of nucleotide metabolic process GO:0006140 117 0.016
ribonucleotide metabolic process GO:0009259 231 0.016
chemical homeostasis GO:0048878 292 0.016
negative regulation of multicellular organismal process GO:0051241 203 0.016
ras protein signal transduction GO:0007265 29 0.016
negative regulation of neuron death GO:1901215 69 0.016
carbohydrate metabolic process GO:0005975 130 0.016
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.016
small gtpase mediated signal transduction GO:0007264 36 0.016
regulation of cellular component organization GO:0051128 368 0.016
axis specification GO:0009798 4 0.016
neuron projection development GO:0031175 273 0.016
nucleoside triphosphate catabolic process GO:0009143 123 0.016
purine nucleoside metabolic process GO:0042278 169 0.016
organic cyclic compound catabolic process GO:1901361 175 0.016
positive regulation of transport GO:0051050 245 0.015
gland development GO:0048732 155 0.015
negative regulation of catalytic activity GO:0043086 103 0.015
sexual reproduction GO:0019953 148 0.015
locomotion GO:0040011 237 0.015
regulation of nervous system development GO:0051960 264 0.015
positive regulation of catalytic activity GO:0043085 184 0.015
positive regulation of cell development GO:0010720 176 0.015
regulation of intracellular signal transduction GO:1902531 218 0.015
cellular response to transforming growth factor beta stimulus GO:0071560 41 0.015
cellular response to reactive oxygen species GO:0034614 55 0.015
regulation of protein kinase activity GO:0045859 105 0.015
central nervous system development GO:0007417 311 0.015
regulation of anatomical structure morphogenesis GO:0022603 141 0.015
cellular ion homeostasis GO:0006873 184 0.015
positive regulation of phosphate metabolic process GO:0045937 262 0.015
purine nucleoside triphosphate catabolic process GO:0009146 122 0.015
reproduction GO:0000003 245 0.014
negative regulation of cell proliferation GO:0008285 119 0.014
response to nutrient GO:0007584 248 0.014
cell part morphogenesis GO:0032990 123 0.014
regulation of cellular catabolic process GO:0031329 101 0.014
peptidyl tyrosine modification GO:0018212 72 0.014
rna biosynthetic process GO:0032774 380 0.014
regulation of neuron differentiation GO:0045664 208 0.014
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.014
cellular response to glucocorticoid stimulus GO:0071385 68 0.014
muscle cell proliferation GO:0033002 84 0.014
negative regulation of phosphorus metabolic process GO:0010563 80 0.014
gastrulation GO:0007369 2 0.014
regulation of synaptic transmission GO:0050804 141 0.014
response to nutrient levels GO:0031667 370 0.013
reactive oxygen species metabolic process GO:0072593 37 0.013
secretion by cell GO:0032940 248 0.013
cellular component movement GO:0006928 248 0.013
response to alkaloid GO:0043279 132 0.013
cellular response to oxidative stress GO:0034599 76 0.013
positive regulation of purine nucleotide metabolic process GO:1900544 91 0.013
cytokine production GO:0001816 61 0.013
positive regulation of cellular component organization GO:0051130 200 0.013
macromolecule localization GO:0033036 252 0.013
positive regulation of apoptotic process GO:0043065 154 0.013
response to lipopolysaccharide GO:0032496 191 0.013
negative regulation of rna biosynthetic process GO:1902679 118 0.013
response to temperature stimulus GO:0009266 94 0.013
aging GO:0007568 241 0.013
gamete generation GO:0007276 124 0.013
action potential GO:0001508 54 0.013
regulation of hydrolase activity GO:0051336 143 0.013
cellular component morphogenesis GO:0032989 155 0.013
blood vessel morphogenesis GO:0048514 58 0.013
g protein coupled receptor signaling pathway GO:0007186 242 0.013
regulation of system process GO:0044057 208 0.013
response to tumor necrosis factor GO:0034612 56 0.013
muscle system process GO:0003012 115 0.013
regulation of catabolic process GO:0009894 113 0.013
positive regulation of response to stimulus GO:0048584 285 0.013
guanosine containing compound metabolic process GO:1901068 74 0.013
positive regulation of programmed cell death GO:0043068 157 0.013
negative regulation of transcription dna templated GO:0045892 116 0.013
single organism carbohydrate metabolic process GO:0044723 118 0.013
positive regulation of cellular protein metabolic process GO:0032270 167 0.013
behavior GO:0007610 205 0.013
blood vessel development GO:0001568 69 0.013
cell motility GO:0048870 202 0.013
regulation of synaptic plasticity GO:0048167 70 0.013
cellular chemical homeostasis GO:0055082 247 0.012
positive regulation of nervous system development GO:0051962 178 0.012
response to toxic substance GO:0009636 133 0.012
regulation of purine nucleotide metabolic process GO:1900542 115 0.012
positive regulation of cellular catabolic process GO:0031331 71 0.012
regulation of embryonic development GO:0045995 2 0.012
nucleobase containing compound catabolic process GO:0034655 152 0.012
negative regulation of phosphorylation GO:0042326 57 0.012
brain development GO:0007420 247 0.012
lipid storage GO:0019915 1 0.012
cytokine biosynthetic process GO:0042089 3 0.012
ribonucleoside metabolic process GO:0009119 174 0.012
regulation of neuron death GO:1901214 115 0.012
cellular nitrogen compound catabolic process GO:0044270 163 0.012
regulation of secretion GO:0051046 224 0.012
aromatic compound catabolic process GO:0019439 168 0.012
circulatory system development GO:0072359 134 0.012
regulation of kinase activity GO:0043549 117 0.012
cellular lipid metabolic process GO:0044255 208 0.012
positive regulation of protein modification process GO:0031401 142 0.012
purine nucleotide metabolic process GO:0006163 229 0.012
bmp signaling pathway GO:0030509 4 0.012
secretion GO:0046903 307 0.012
guanosine containing compound catabolic process GO:1901069 71 0.012
organonitrogen compound catabolic process GO:1901565 179 0.012
locomotor rhythm GO:0045475 1 0.011
nucleotide catabolic process GO:0009166 139 0.011
nucleoside triphosphate metabolic process GO:0009141 144 0.011
embryonic pattern specification GO:0009880 1 0.011
purine containing compound catabolic process GO:0072523 138 0.011
cellular macromolecule localization GO:0070727 122 0.011
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 27 0.011
purine ribonucleoside metabolic process GO:0046128 168 0.011
single organism catabolic process GO:0044712 283 0.011
signal transduction by phosphorylation GO:0023014 144 0.011
response to ethanol GO:0045471 162 0.011
regulation of dna metabolic process GO:0051052 60 0.011
cell type specific apoptotic process GO:0097285 134 0.011
positive regulation of cellular amine metabolic process GO:0033240 3 0.011
regulation of cytokine biosynthetic process GO:0042035 3 0.011
negative regulation of phosphate metabolic process GO:0045936 80 0.011
mapk cascade GO:0000165 140 0.011
response to wounding GO:0009611 254 0.011
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.011
positive regulation of catabolic process GO:0009896 78 0.011
spermatogenesis GO:0007283 99 0.011
purine nucleoside triphosphate metabolic process GO:0009144 141 0.011
multicellular organismal signaling GO:0035637 44 0.011
head development GO:0060322 247 0.011
positive regulation of protein metabolic process GO:0051247 178 0.011
cell migration GO:0016477 197 0.011
rho protein signal transduction GO:0007266 11 0.011
cellular carbohydrate metabolic process GO:0044262 72 0.010
positive regulation of phosphorylation GO:0042327 177 0.010
neuronal action potential GO:0019228 35 0.010
carbohydrate derivative catabolic process GO:1901136 147 0.010
regulation of proteasomal protein catabolic process GO:0061136 4 0.010
positive regulation of neurogenesis GO:0050769 165 0.010
protein localization GO:0008104 191 0.010
response to hexose GO:0009746 144 0.010
reactive nitrogen species metabolic process GO:2001057 1 0.010
cation homeostasis GO:0055080 195 0.010
proteolysis GO:0006508 175 0.010
positive regulation of nucleoside metabolic process GO:0045979 55 0.010
regulation of erk1 and erk2 cascade GO:0070372 41 0.010
negative regulation of nf kappab transcription factor activity GO:0032088 4 0.010

Tiparp disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.012
nervous system disease DOID:863 0 0.012
disease of cellular proliferation DOID:14566 0 0.010