Rattus norvegicus

35 known processes

Eif5a

eukaryotic translation initiation factor 5A

(Aliases: MGC124873)

Eif5a biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
response to cytokine GO:0034097 215 0.487
tissue development GO:0009888 252 0.295
regulation of cellular component organization GO:0051128 368 0.270
cellular component assembly GO:0022607 360 0.263
macromolecular complex subunit organization GO:0043933 339 0.228
cellular response to cytokine stimulus GO:0071345 127 0.224
cellular component biogenesis GO:0044085 368 0.194
regulation of phosphate metabolic process GO:0019220 349 0.169
response to purine containing compound GO:0014074 126 0.161
positive regulation of phosphate metabolic process GO:0045937 262 0.152
programmed cell death GO:0012501 392 0.140
regulation of cellular protein metabolic process GO:0032268 267 0.114
organophosphate biosynthetic process GO:0090407 143 0.113
macromolecular complex assembly GO:0065003 273 0.108
receptor internalization GO:0031623 14 0.103
organic substance catabolic process GO:1901575 316 0.098
cell cycle GO:0007049 101 0.094
intracellular transport GO:0046907 185 0.094
regulation of cell development GO:0060284 263 0.092
protein complex subunit organization GO:0071822 302 0.090
positive regulation of phosphorus metabolic process GO:0010562 262 0.089
cell cycle process GO:0022402 57 0.087
cardiovascular system development GO:0072358 134 0.081
anatomical structure morphogenesis GO:0009653 298 0.080
cellular macromolecular complex assembly GO:0034622 58 0.079
cell projection organization GO:0030030 302 0.077
regulation of cellular catabolic process GO:0031329 101 0.075
regulation of organelle organization GO:0033043 80 0.072
positive regulation of response to stimulus GO:0048584 285 0.070
organonitrogen compound biosynthetic process GO:1901566 167 0.069
positive regulation of cellular component organization GO:0051130 200 0.068
positive regulation of cellular biosynthetic process GO:0031328 295 0.065
positive regulation of biosynthetic process GO:0009891 319 0.065
regulation of phosphorus metabolic process GO:0051174 349 0.065
purine containing compound metabolic process GO:0072521 253 0.064
negative regulation of metabolic process GO:0009892 331 0.060
positive regulation of cellular component biogenesis GO:0044089 55 0.060
regulation of meiotic cell cycle GO:0051445 3 0.060
protein phosphorylation GO:0006468 345 0.059
locomotion GO:0040011 237 0.057
protein complex assembly GO:0006461 263 0.057
nucleoside phosphate metabolic process GO:0006753 283 0.057
regulation of transcription dna templated GO:0006355 374 0.057
polyamine biosynthetic process GO:0006596 4 0.057
rna biosynthetic process GO:0032774 380 0.057
dephosphorylation GO:0016311 98 0.056
generation of precursor metabolites and energy GO:0006091 62 0.055
macromolecule localization GO:0033036 252 0.053
tube development GO:0035295 89 0.052
protein complex biogenesis GO:0070271 263 0.051
apoptotic process GO:0006915 381 0.050
regulation of protein phosphorylation GO:0001932 183 0.049
muscle tissue morphogenesis GO:0060415 1 0.049
posttranscriptional regulation of gene expression GO:0010608 37 0.049
regulation of protein modification process GO:0031399 194 0.048
rna metabolic process GO:0016070 406 0.046
purine ribonucleotide metabolic process GO:0009150 227 0.046
circulatory system development GO:0072359 134 0.045
positive regulation of protein metabolic process GO:0051247 178 0.045
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.045
positive regulation of catalytic activity GO:0043085 184 0.044
positive regulation of protein modification process GO:0031401 142 0.043
nucleic acid templated transcription GO:0097659 379 0.043
heart development GO:0007507 72 0.043
regulation of programmed cell death GO:0043067 341 0.043
ribonucleotide metabolic process GO:0009259 231 0.043
regulation of neuron differentiation GO:0045664 208 0.042
hematopoietic progenitor cell differentiation GO:0002244 2 0.041
positive regulation of phosphorylation GO:0042327 177 0.040
cellular protein complex assembly GO:0043623 44 0.040
amine metabolic process GO:0009308 38 0.040
regulation of apoptotic process GO:0042981 335 0.039
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.038
regulation of neurogenesis GO:0050767 247 0.038
negative regulation of apoptotic process GO:0043066 181 0.038
nucleocytoplasmic transport GO:0006913 48 0.038
neuron differentiation GO:0030182 368 0.037
purine nucleotide catabolic process GO:0006195 136 0.037
negative regulation of cell death GO:0060548 229 0.037
regulation of protein polymerization GO:0032271 19 0.036
single organism organelle organization GO:1902589 180 0.036
homeostatic process GO:0042592 331 0.036
neuron projection development GO:0031175 273 0.036
cellular response to growth factor stimulus GO:0071363 162 0.035
positive regulation of cell death GO:0010942 184 0.035
positive regulation of organelle organization GO:0010638 48 0.035
nucleoside phosphate biosynthetic process GO:1901293 102 0.034
cellular amine metabolic process GO:0044106 38 0.034
regulation of multicellular organismal development GO:2000026 376 0.032
regulation of nucleotide metabolic process GO:0006140 117 0.032
organophosphate metabolic process GO:0019637 370 0.032
lipid localization GO:0010876 62 0.031
multi organism reproductive process GO:0044703 262 0.031
modification dependent macromolecule catabolic process GO:0043632 14 0.031
positive regulation of gene expression GO:0010628 244 0.031
endocytosis GO:0006897 84 0.031
regulation of nervous system development GO:0051960 264 0.031
positive regulation of apoptotic process GO:0043065 154 0.031
eye development GO:0001654 50 0.030
positive regulation of nucleotide metabolic process GO:0045981 91 0.029
regulation of purine nucleotide metabolic process GO:1900542 115 0.028
cellular homeostasis GO:0019725 252 0.028
aging GO:0007568 241 0.028
cellular protein catabolic process GO:0044257 19 0.028
regulation of signal transduction GO:0009966 318 0.028
receptor mediated endocytosis GO:0006898 42 0.027
positive regulation of cellular protein metabolic process GO:0032270 167 0.027
protein import into nucleus GO:0006606 35 0.027
ribosomal small subunit biogenesis GO:0042274 6 0.027
cytoplasmic transport GO:0016482 115 0.026
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.026
negative regulation of cell development GO:0010721 82 0.026
negative regulation of signaling GO:0023057 157 0.026
regulation of phosphorylation GO:0042325 248 0.025
carbohydrate derivative metabolic process GO:1901135 346 0.025
single organism reproductive process GO:0044702 297 0.025
tissue morphogenesis GO:0048729 22 0.024
reproduction GO:0000003 245 0.024
positive regulation of signal transduction GO:0009967 175 0.024
purine nucleotide metabolic process GO:0006163 229 0.024
purine ribonucleoside triphosphate metabolic process GO:0009205 140 0.024
nucleotide metabolic process GO:0009117 279 0.024
positive regulation of cell communication GO:0010647 271 0.024
hematopoietic or lymphoid organ development GO:0048534 36 0.024
circadian regulation of gene expression GO:0032922 3 0.024
maintenance of location GO:0051235 17 0.024
enzyme linked receptor protein signaling pathway GO:0007167 116 0.023
organic acid transport GO:0015849 116 0.023
positive regulation of programmed cell death GO:0043068 157 0.023
glycosyl compound metabolic process GO:1901657 182 0.023
transcription dna templated GO:0006351 377 0.023
cellular catabolic process GO:0044248 295 0.023
lipid storage GO:0019915 1 0.023
multicellular organism reproduction GO:0032504 233 0.023
cardiac muscle tissue development GO:0048738 26 0.023
muscle cell differentiation GO:0042692 52 0.023
positive regulation of protein phosphorylation GO:0001934 135 0.022
ribose phosphate metabolic process GO:0019693 235 0.022
carboxylic acid metabolic process GO:0019752 289 0.022
positive regulation of endocytosis GO:0045807 28 0.022
positive regulation of hydrolase activity GO:0051345 86 0.022
positive regulation of nucleic acid templated transcription GO:1903508 197 0.021
neuron development GO:0048666 286 0.021
positive regulation of purine nucleotide biosynthetic process GO:1900373 36 0.021
proteasomal protein catabolic process GO:0010498 8 0.021
positive regulation of rna biosynthetic process GO:1902680 197 0.021
cellular component movement GO:0006928 248 0.021
organic cyclic compound catabolic process GO:1901361 175 0.021
multicellular organismal reproductive process GO:0048609 233 0.020
proteolysis involved in cellular protein catabolic process GO:0051603 19 0.020
guanosine containing compound metabolic process GO:1901068 74 0.020
regulation of cellular component biogenesis GO:0044087 86 0.020
positive regulation of developmental process GO:0051094 283 0.020
chemical homeostasis GO:0048878 292 0.020
anaphase promoting complex dependent proteasomal ubiquitin dependent protein catabolic process GO:0031145 1 0.019
energy derivation by oxidation of organic compounds GO:0015980 46 0.019
negative regulation of macromolecule metabolic process GO:0010605 260 0.019
heart morphogenesis GO:0003007 3 0.019
cell migration GO:0016477 197 0.019
cell morphogenesis GO:0000902 142 0.019
brain development GO:0007420 247 0.019
nucleoside metabolic process GO:0009116 179 0.019
central nervous system development GO:0007417 311 0.019
positive regulation of molecular function GO:0044093 230 0.019
regulation of cell growth GO:0001558 85 0.019
negative regulation of cellular metabolic process GO:0031324 281 0.019
negative regulation of cell communication GO:0010648 158 0.018
organelle organization GO:0006996 266 0.018
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.018
regulation of arp2 3 complex mediated actin nucleation GO:0034315 2 0.018
regulation of catabolic process GO:0009894 113 0.018
positive regulation of transport GO:0051050 245 0.018
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.018
eye morphogenesis GO:0048592 4 0.018
regulation of neuron projection development GO:0010975 161 0.018
regulation of transferase activity GO:0051338 123 0.018
cell part morphogenesis GO:0032990 123 0.018
oxoacid metabolic process GO:0043436 290 0.018
response to growth factor GO:0070848 189 0.018
response to peptide hormone GO:0043434 278 0.018
negative regulation of protein modification by small protein conjugation or removal GO:1903321 4 0.017
regulation of catalytic activity GO:0050790 304 0.017
purine ribonucleoside metabolic process GO:0046128 168 0.017
growth GO:0040007 165 0.017
cellular chemical homeostasis GO:0055082 247 0.017
translation GO:0006412 35 0.017
nucleoside phosphate catabolic process GO:1901292 140 0.017
pyrimidine nucleoside triphosphate biosynthetic process GO:0009148 3 0.017
localization of cell GO:0051674 202 0.017
nucleobase containing small molecule metabolic process GO:0055086 316 0.017
positive regulation of multicellular organismal process GO:0051240 387 0.017
nuclear import GO:0051170 35 0.016
gland development GO:0048732 155 0.016
positive regulation of cellular catabolic process GO:0031331 71 0.016
muscle organ morphogenesis GO:0048644 1 0.016
regulation of nucleotide catabolic process GO:0030811 65 0.016
cation homeostasis GO:0055080 195 0.016
regulation of cell projection organization GO:0031344 175 0.016
catabolic process GO:0009056 351 0.015
carbohydrate derivative biosynthetic process GO:1901137 124 0.015
regulation of protein metabolic process GO:0051246 289 0.015
regulation of immune system process GO:0002682 123 0.015
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 7 0.015
biological adhesion GO:0022610 110 0.015
sensory organ development GO:0007423 74 0.015
organonitrogen compound catabolic process GO:1901565 179 0.015
cellular biogenic amine biosynthetic process GO:0042401 4 0.015
peptidyl amino acid modification GO:0018193 126 0.015
nuclear transport GO:0051169 49 0.015
triglyceride homeostasis GO:0070328 2 0.015
pyrimidine nucleoside triphosphate metabolic process GO:0009147 4 0.015
cell growth GO:0016049 104 0.015
negative regulation of myeloid cell differentiation GO:0045638 3 0.014
regulation of molecular function GO:0065009 398 0.014
protein oligomerization GO:0051259 191 0.014
regulation of nucleic acid templated transcription GO:1903506 380 0.014
purine nucleoside triphosphate metabolic process GO:0009144 141 0.014
cellular metal ion homeostasis GO:0006875 172 0.014
regulation of nucleoside metabolic process GO:0009118 66 0.014
negative regulation of cell differentiation GO:0045596 99 0.013
positive regulation of gtp catabolic process GO:0033126 48 0.013
positive regulation of transcription dna templated GO:0045893 197 0.013
regulation of hydrolase activity GO:0051336 143 0.013
regulation of cell differentiation GO:0045595 320 0.013
regulation of cell migration GO:0030334 128 0.013
cation transport GO:0006812 382 0.013
regulation of locomotion GO:0040012 148 0.013
coenzyme metabolic process GO:0006732 86 0.013
cellular macromolecule catabolic process GO:0044265 29 0.013
er to golgi vesicle mediated transport GO:0006888 10 0.013
cell motility GO:0048870 202 0.013
regulation of rna metabolic process GO:0051252 391 0.013
intracellular signal transduction GO:0035556 314 0.013
positive regulation of catabolic process GO:0009896 78 0.013
regulation of canonical wnt signaling pathway GO:0060828 4 0.012
positive regulation of actin filament polymerization GO:0030838 5 0.012
ribonucleotide biosynthetic process GO:0009260 85 0.012
regulation of cellular amino acid metabolic process GO:0006521 2 0.012
acylglycerol homeostasis GO:0055090 2 0.012
amino acid transport GO:0006865 70 0.012
purine nucleoside metabolic process GO:0042278 169 0.012
purine nucleoside biosynthetic process GO:0042451 21 0.012
male gamete generation GO:0048232 99 0.012
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.012
g protein coupled receptor signaling pathway GO:0007186 242 0.012
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.012
cardiocyte differentiation GO:0035051 22 0.012
cellular amino acid metabolic process GO:0006520 107 0.012
negative regulation of nucleic acid templated transcription GO:1903507 117 0.012
developmental growth GO:0048589 100 0.012
cellular response to stress GO:0033554 269 0.012
cellular nitrogen compound catabolic process GO:0044270 163 0.011
regulation of cellular component size GO:0032535 51 0.011
regulation of rna biosynthetic process GO:2001141 381 0.011
regulation of cell motility GO:2000145 131 0.011
organ morphogenesis GO:0009887 75 0.011
regulation of actin nucleation GO:0051125 2 0.011
regulation of cellular localization GO:0060341 263 0.011
spermatogenesis GO:0007283 99 0.011
negative regulation of gene expression GO:0010629 199 0.011
regulation of ubiquitin protein transferase activity GO:0051438 1 0.011
regulation of vesicle mediated transport GO:0060627 81 0.011
aromatic compound catabolic process GO:0019439 168 0.011
regulation of actin filament based process GO:0032970 42 0.011
purine nucleoside monophosphate biosynthetic process GO:0009127 20 0.011
regulation of cell morphogenesis GO:0022604 77 0.011
regulation of synaptic plasticity GO:0048167 70 0.011
cellular ion homeostasis GO:0006873 184 0.011
purine containing compound catabolic process GO:0072523 138 0.011
positive regulation of transferase activity GO:0051347 81 0.011
regulation of protein kinase activity GO:0045859 105 0.011
organelle fission GO:0048285 25 0.011
regulation of myeloid leukocyte differentiation GO:0002761 12 0.010
positive regulation of cell proliferation GO:0008284 249 0.010
striated muscle cell differentiation GO:0051146 39 0.010
synaptic transmission GO:0007268 235 0.010
angiogenesis GO:0001525 53 0.010
macroautophagy GO:0016236 4 0.010
purine nucleoside monophosphate metabolic process GO:0009126 84 0.010
regulation of intracellular signal transduction GO:1902531 218 0.010
neuron death GO:0070997 127 0.010
positive regulation of purine nucleotide metabolic process GO:1900544 91 0.010
positive regulation of rna metabolic process GO:0051254 203 0.010
cellular response to extracellular stimulus GO:0031668 73 0.010
cation transmembrane transport GO:0098655 263 0.010
cardiac cell development GO:0055006 16 0.010
hemopoiesis GO:0030097 34 0.010
carboxylic acid transport GO:0046942 115 0.010
regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032434 3 0.010
single organism catabolic process GO:0044712 283 0.010

Eif5a disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.053
nervous system disease DOID:863 0 0.053
cancer DOID:162 0 0.020
disease of cellular proliferation DOID:14566 0 0.020
organ system cancer DOID:0050686 0 0.020