Rattus norvegicus

0 known processes

Nphp4

nephronophthisis 4 (juvenile) homolog (human)

(Aliases: MGC125230)

Nphp4 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
protein complex biogenesis GO:0070271 263 0.068
cell projection morphogenesis GO:0048858 123 0.067
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.064
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.063
cellular component morphogenesis GO:0032989 155 0.060
neuron differentiation GO:0030182 368 0.055
cellular component biogenesis GO:0044085 368 0.052
cellular component assembly GO:0022607 360 0.051
cell morphogenesis involved in neuron differentiation GO:0048667 106 0.049
axon development GO:0061564 96 0.049
cell projection organization GO:0030030 302 0.048
neuron development GO:0048666 286 0.047
carboxylic acid metabolic process GO:0019752 289 0.047
oxoacid metabolic process GO:0043436 290 0.047
cell morphogenesis involved in differentiation GO:0000904 119 0.046
negative regulation of macromolecule metabolic process GO:0010605 260 0.046
negative regulation of cellular biosynthetic process GO:0031327 161 0.044
regulation of cellular component organization GO:0051128 368 0.044
negative regulation of cellular metabolic process GO:0031324 281 0.044
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.040
regulation of molecular function GO:0065009 398 0.039
positive regulation of biosynthetic process GO:0009891 319 0.039
intracellular signal transduction GO:0035556 314 0.038
rna metabolic process GO:0016070 406 0.037
rna biosynthetic process GO:0032774 380 0.037
anterior posterior pattern specification GO:0009952 1 0.036
macromolecular complex assembly GO:0065003 273 0.036
neuron projection development GO:0031175 273 0.034
nucleic acid templated transcription GO:0097659 379 0.034
positive regulation of cellular biosynthetic process GO:0031328 295 0.034
response to corticosteroid GO:0031960 235 0.034
positive regulation of transport GO:0051050 245 0.033
cellular amine metabolic process GO:0044106 38 0.033
regulation of rna metabolic process GO:0051252 391 0.033
transcription dna templated GO:0006351 377 0.033
negative regulation of metabolic process GO:0009892 331 0.032
organic acid metabolic process GO:0006082 292 0.032
cell cell signaling GO:0007267 335 0.032
regulation of nucleic acid templated transcription GO:1903506 380 0.032
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.031
cell morphogenesis GO:0000902 142 0.030
regulation of cell differentiation GO:0045595 320 0.030
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.030
negative regulation of rna metabolic process GO:0051253 123 0.030
neuron projection morphogenesis GO:0048812 122 0.030
cellular catabolic process GO:0044248 295 0.029
regulation of cellular localization GO:0060341 263 0.029
negative regulation of rna biosynthetic process GO:1902679 118 0.029
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.028
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.028
positive regulation of cellular component organization GO:0051130 200 0.027
organophosphate metabolic process GO:0019637 370 0.027
intracellular transport GO:0046907 185 0.027
catabolic process GO:0009056 351 0.027
positive regulation of molecular function GO:0044093 230 0.027
developmental process involved in reproduction GO:0003006 159 0.026
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 85 0.026
muscle structure development GO:0061061 87 0.026
organelle organization GO:0006996 266 0.026
negative regulation of transcription dna templated GO:0045892 116 0.026
nitrogen compound transport GO:0071705 229 0.026
protein complex assembly GO:0006461 263 0.026
protein phosphorylation GO:0006468 345 0.026
response to metal ion GO:0010038 253 0.026
cell cycle GO:0007049 101 0.026
tissue development GO:0009888 252 0.026
negative regulation of biosynthetic process GO:0009890 168 0.025
positive regulation of multicellular organismal process GO:0051240 387 0.025
negative regulation of gene expression GO:0010629 199 0.025
negative regulation of nucleic acid templated transcription GO:1903507 117 0.025
regulation of cellular amino acid metabolic process GO:0006521 2 0.024
chemical homeostasis GO:0048878 292 0.024
single organism organelle organization GO:1902589 180 0.024
regulation of secretion by cell GO:1903530 208 0.024
nucleoside phosphate metabolic process GO:0006753 283 0.024
regulation of catalytic activity GO:0050790 304 0.024
positive regulation of rna biosynthetic process GO:1902680 197 0.023
cellular response to stress GO:0033554 269 0.023
cell part morphogenesis GO:0032990 123 0.023
cellular homeostasis GO:0019725 252 0.023
vesicle mediated transport GO:0016192 181 0.023
central nervous system development GO:0007417 311 0.023
positive regulation of gene expression GO:0010628 244 0.022
heart morphogenesis GO:0003007 3 0.022
single organism catabolic process GO:0044712 283 0.022
reproductive process GO:0022414 372 0.022
embryonic pattern specification GO:0009880 1 0.022
single organism biosynthetic process GO:0044711 342 0.022
regulation of phosphate metabolic process GO:0019220 349 0.022
regulation of ion transport GO:0043269 245 0.022
response to oxidative stress GO:0006979 186 0.022
cellular nitrogen compound catabolic process GO:0044270 163 0.022
amine metabolic process GO:0009308 38 0.022
positive regulation of nucleic acid templated transcription GO:1903508 197 0.022
regulation of hormone levels GO:0010817 187 0.021
cellular amino acid metabolic process GO:0006520 107 0.021
axonogenesis GO:0007409 71 0.021
macromolecular complex subunit organization GO:0043933 339 0.021
regulation of multicellular organismal development GO:2000026 376 0.021
regulation of cell projection organization GO:0031344 175 0.021
positive regulation of cell proliferation GO:0008284 249 0.021
axis specification GO:0009798 4 0.021
regulation of transcription dna templated GO:0006355 374 0.021
anatomical structure morphogenesis GO:0009653 298 0.021
macromolecule localization GO:0033036 252 0.020
single organism intracellular transport GO:1902582 166 0.020
protein complex subunit organization GO:0071822 302 0.020
regulation of neuron projection development GO:0010975 161 0.020
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.020
regulation of rna biosynthetic process GO:2001141 381 0.020
organic substance catabolic process GO:1901575 316 0.020
response to inorganic substance GO:0010035 377 0.019
regulation of phosphorus metabolic process GO:0051174 349 0.019
response to cytokine GO:0034097 215 0.019
apoptotic process GO:0006915 381 0.019
eye morphogenesis GO:0048592 4 0.019
regulation of protein metabolic process GO:0051246 289 0.019
multicellular organismal reproductive process GO:0048609 233 0.019
protein oligomerization GO:0051259 191 0.019
positive regulation of rna metabolic process GO:0051254 203 0.018
regulation of signal transduction GO:0009966 318 0.018
lipid metabolic process GO:0006629 283 0.018
peptide secretion GO:0002790 86 0.018
regulation of ion transmembrane transport GO:0034765 121 0.018
protein localization GO:0008104 191 0.018
positive regulation of transcription dna templated GO:0045893 197 0.018
response to wounding GO:0009611 254 0.017
positive regulation of cell development GO:0010720 176 0.017
wound healing GO:0042060 122 0.017
cellular ketone metabolic process GO:0042180 51 0.017
response to nutrient GO:0007584 248 0.017
positive regulation of neuron differentiation GO:0045666 126 0.017
cytoplasmic transport GO:0016482 115 0.017
cellular component movement GO:0006928 248 0.017
secretion GO:0046903 307 0.017
signal release GO:0023061 145 0.017
gamete generation GO:0007276 124 0.017
salivary gland morphogenesis GO:0007435 1 0.017
regulation of cell morphogenesis GO:0022604 77 0.016
programmed cell death GO:0012501 392 0.016
regulation of cellular amine metabolic process GO:0033238 8 0.016
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.016
positive regulation of signal transduction GO:0009967 175 0.016
regulation of neuron differentiation GO:0045664 208 0.016
small gtpase mediated signal transduction GO:0007264 36 0.016
amide transport GO:0042886 105 0.016
response to glucose GO:0009749 136 0.016
response to hexose GO:0009746 144 0.016
positive regulation of cellular amine metabolic process GO:0033240 3 0.016
reproduction GO:0000003 245 0.016
positive regulation of phosphorus metabolic process GO:0010562 262 0.016
regulation of cellular ketone metabolic process GO:0010565 27 0.015
cellular response to growth factor stimulus GO:0071363 162 0.015
regulation of cell development GO:0060284 263 0.015
organic cyclic compound catabolic process GO:1901361 175 0.015
carbohydrate derivative metabolic process GO:1901135 346 0.015
locomotion GO:0040011 237 0.015
organic hydroxy compound metabolic process GO:1901615 115 0.015
ion transmembrane transport GO:0034220 365 0.015
positive regulation of nervous system development GO:0051962 178 0.015
regulation of insulin secretion GO:0050796 65 0.015
positive regulation of cell communication GO:0010647 271 0.015
nucleotide metabolic process GO:0009117 279 0.014
establishment of protein localization GO:0045184 141 0.014
regulation of catabolic process GO:0009894 113 0.014
regulation of peptide secretion GO:0002791 82 0.014
single organism reproductive process GO:0044702 297 0.014
positive regulation of developmental process GO:0051094 283 0.014
enzyme linked receptor protein signaling pathway GO:0007167 116 0.014
positive regulation of cell differentiation GO:0045597 217 0.014
heterocycle catabolic process GO:0046700 167 0.014
ion homeostasis GO:0050801 212 0.014
single organism carbohydrate metabolic process GO:0044723 118 0.014
response to carbohydrate GO:0009743 183 0.014
cellular response to cytokine stimulus GO:0071345 127 0.014
cellular metal ion homeostasis GO:0006875 172 0.014
cellular response to endogenous stimulus GO:0071495 377 0.014
positive regulation of cell death GO:0010942 184 0.014
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.014
transmembrane transport GO:0055085 412 0.014
meiotic cell cycle process GO:1903046 3 0.014
regulation of hydrolase activity GO:0051336 143 0.014
positive regulation of catalytic activity GO:0043085 184 0.014
cardiac chamber development GO:0003205 1 0.014
regulation of transmembrane transport GO:0034762 122 0.013
ras protein signal transduction GO:0007265 29 0.013
positive regulation of neurogenesis GO:0050769 165 0.013
regulation of metal ion transport GO:0010959 118 0.013
dna metabolic process GO:0006259 96 0.013
inorganic ion transmembrane transport GO:0098660 229 0.013
protein transport GO:0015031 132 0.013
establishment of tissue polarity GO:0007164 2 0.013
calcium ion homeostasis GO:0055074 162 0.013
fatty acid metabolic process GO:0006631 99 0.013
regulation of anatomical structure morphogenesis GO:0022603 141 0.013
negative regulation of cellular component organization GO:0051129 83 0.013
striated muscle tissue development GO:0014706 58 0.013
regulation of nervous system development GO:0051960 264 0.013
transmission of nerve impulse GO:0019226 42 0.013
regulation of cell cycle GO:0051726 73 0.013
response to vitamin GO:0033273 131 0.013
positive regulation of secretion GO:0051047 140 0.013
hormone transport GO:0009914 121 0.013
metal ion transport GO:0030001 289 0.013
regulation of secretion GO:0051046 224 0.013
response to extracellular stimulus GO:0009991 380 0.013
regulation of cellular protein metabolic process GO:0032268 267 0.012
positive regulation of response to stimulus GO:0048584 285 0.012
lipid biosynthetic process GO:0008610 128 0.012
positive regulation of cell projection organization GO:0031346 111 0.012
regulation of intracellular signal transduction GO:1902531 218 0.012
regulation of phosphorylation GO:0042325 248 0.012
muscle tissue development GO:0060537 58 0.012
purine ribonucleotide metabolic process GO:0009150 227 0.012
regulation of embryonic development GO:0045995 2 0.012
regulation of organelle organization GO:0033043 80 0.012
negative regulation of developmental process GO:0051093 125 0.012
reproductive system development GO:0061458 128 0.012
response to decreased oxygen levels GO:0036293 237 0.012
negative regulation of cell development GO:0010721 82 0.012
positive regulation of secretion by cell GO:1903532 128 0.012
cell cycle checkpoint GO:0000075 2 0.012
response to glucocorticoid GO:0051384 223 0.012
regulation of peptide hormone secretion GO:0090276 80 0.012
cell growth GO:0016049 104 0.012
multi organism reproductive process GO:0044703 262 0.012
peptide hormone secretion GO:0030072 84 0.012
growth GO:0040007 165 0.012
divalent metal ion transport GO:0070838 132 0.012
response to monosaccharide GO:0034284 159 0.012
cellular response to external stimulus GO:0071496 118 0.012
positive regulation of phosphate metabolic process GO:0045937 262 0.012
regulation of programmed cell death GO:0043067 341 0.012
response to nutrient levels GO:0031667 370 0.012
insulin secretion GO:0030073 69 0.012
anatomical structure formation involved in morphogenesis GO:0048646 83 0.012
monocarboxylic acid metabolic process GO:0032787 152 0.012
hormone secretion GO:0046879 115 0.012
syncytium formation by plasma membrane fusion GO:0000768 3 0.011
secretion by cell GO:0032940 248 0.011
olfactory behavior GO:0042048 2 0.011
brain development GO:0007420 247 0.011
rna localization GO:0006403 4 0.011
gastrulation GO:0007369 2 0.011
regulation of hormone secretion GO:0046883 106 0.011
peptidyl amino acid modification GO:0018193 126 0.011
regulation of apoptotic process GO:0042981 335 0.011
transcription from rna polymerase ii promoter GO:0006366 252 0.011
regulation of peptide transport GO:0090087 87 0.011
positive regulation of protein phosphorylation GO:0001934 135 0.011
negative regulation of cell death GO:0060548 229 0.011
organonitrogen compound catabolic process GO:1901565 179 0.011
response to growth factor GO:0070848 189 0.011
multicellular organism growth GO:0035264 1 0.011
regulation of transferase activity GO:0051338 123 0.011
limb morphogenesis GO:0035108 4 0.011
negative regulation of transport GO:0051051 136 0.011
development of primary sexual characteristics GO:0045137 107 0.011
dendrite development GO:0016358 72 0.011
positive regulation of signaling GO:0023056 270 0.011
regulation of purine nucleotide metabolic process GO:1900542 115 0.011
cilium morphogenesis GO:0060271 2 0.011
response to molecule of bacterial origin GO:0002237 194 0.011
synaptic transmission GO:0007268 235 0.011
positive regulation of protein metabolic process GO:0051247 178 0.011
female gonad development GO:0008585 53 0.011
negative regulation of signaling GO:0023057 157 0.011
nucleobase containing small molecule metabolic process GO:0055086 316 0.011
response to axon injury GO:0048678 59 0.011
cellular cation homeostasis GO:0030003 180 0.010
purine nucleotide catabolic process GO:0006195 136 0.010
chemotaxis GO:0006935 66 0.010
inorganic cation transmembrane transport GO:0098662 202 0.010
negative regulation of catalytic activity GO:0043086 103 0.010
retina morphogenesis in camera type eye GO:0060042 1 0.010
myoblast fusion GO:0007520 2 0.010
response to reactive oxygen species GO:0000302 120 0.010
aromatic compound catabolic process GO:0019439 168 0.010
nucleoside phosphate catabolic process GO:1901292 140 0.010
syncytium formation GO:0006949 4 0.010
negative regulation of programmed cell death GO:0043069 183 0.010
regulation of proteasomal protein catabolic process GO:0061136 4 0.010
cellular response to oxygen containing compound GO:1901701 386 0.010
cell type specific apoptotic process GO:0097285 134 0.010
proteolysis GO:0006508 175 0.010
cell cell signaling involved in cell fate commitment GO:0045168 2 0.010
developmental growth GO:0048589 100 0.010
response to acid chemical GO:0001101 222 0.010
divalent inorganic cation homeostasis GO:0072507 165 0.010
cardiac ventricle development GO:0003231 1 0.010

Nphp4 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.044
nervous system disease DOID:863 0 0.044
sensory system disease DOID:0050155 0 0.026
eye and adnexa disease DOID:1492 0 0.021
eye disease DOID:5614 0 0.021
musculoskeletal system disease DOID:17 0 0.017
retinal disease DOID:5679 0 0.014