Rattus norvegicus

0 known processes

Sh3bp4

SH3-domain binding protein 4

(Aliases: MAGI)

Sh3bp4 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
tissue development GO:0009888 252 0.102
regulation of cell proliferation GO:0042127 359 0.082
Human
regulation of phosphorylation GO:0042325 248 0.081
protein phosphorylation GO:0006468 345 0.079
cellular component movement GO:0006928 248 0.075
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.064
regulation of phosphate metabolic process GO:0019220 349 0.064
Human
regulation of signal transduction GO:0009966 318 0.062
Human
regulation of molecular function GO:0065009 398 0.062
Human
response to extracellular stimulus GO:0009991 380 0.060
organic acid metabolic process GO:0006082 292 0.060
intracellular signal transduction GO:0035556 314 0.059
Human
regulation of cellular protein metabolic process GO:0032268 267 0.057
regulation of programmed cell death GO:0043067 341 0.057
regulation of nucleic acid templated transcription GO:1903506 380 0.055
regulation of phosphorus metabolic process GO:0051174 349 0.053
Human
positive regulation of biosynthetic process GO:0009891 319 0.051
reproductive process GO:0022414 372 0.051
locomotion GO:0040011 237 0.050
nucleic acid templated transcription GO:0097659 379 0.050
oxoacid metabolic process GO:0043436 290 0.049
regulation of protein modification process GO:0031399 194 0.049
negative regulation of cellular metabolic process GO:0031324 281 0.049
Human
carboxylic acid metabolic process GO:0019752 289 0.048
positive regulation of cell proliferation GO:0008284 249 0.048
cellular response to oxygen containing compound GO:1901701 386 0.048
Human
regulation of cell differentiation GO:0045595 320 0.047
anatomical structure morphogenesis GO:0009653 298 0.046
localization of cell GO:0051674 202 0.046
regulation of nervous system development GO:0051960 264 0.046
regulation of protein metabolic process GO:0051246 289 0.045
transcription dna templated GO:0006351 377 0.045
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.044
regulation of cellular component organization GO:0051128 368 0.044
Human
negative regulation of macromolecule metabolic process GO:0010605 260 0.044
regulation of intracellular signal transduction GO:1902531 218 0.043
Human
rna metabolic process GO:0016070 406 0.042
regulation of neurogenesis GO:0050767 247 0.042
regulation of cellular ketone metabolic process GO:0010565 27 0.042
single organism intracellular transport GO:1902582 166 0.041
positive regulation of response to stimulus GO:0048584 285 0.041
cellular response to stress GO:0033554 269 0.041
neuron differentiation GO:0030182 368 0.040
carbohydrate derivative metabolic process GO:1901135 346 0.039
Human
positive regulation of cellular protein metabolic process GO:0032270 167 0.039
single organism biosynthetic process GO:0044711 342 0.038
positive regulation of cellular biosynthetic process GO:0031328 295 0.038
organelle organization GO:0006996 266 0.038
cellular component biogenesis GO:0044085 368 0.037
positive regulation of protein metabolic process GO:0051247 178 0.037
regulation of multicellular organismal development GO:2000026 376 0.037
positive regulation of developmental process GO:0051094 283 0.037
positive regulation of gene expression GO:0010628 244 0.036
single organism reproductive process GO:0044702 297 0.036
cellular component assembly GO:0022607 360 0.035
cell projection organization GO:0030030 302 0.035
regulation of rna metabolic process GO:0051252 391 0.035
cellular amino acid metabolic process GO:0006520 107 0.034
cell migration GO:0016477 197 0.034
regulation of cellular amine metabolic process GO:0033238 8 0.034
cellular ketone metabolic process GO:0042180 51 0.034
positive regulation of signal transduction GO:0009967 175 0.034
regulation of protein phosphorylation GO:0001932 183 0.034
rna biosynthetic process GO:0032774 380 0.033
catabolic process GO:0009056 351 0.033
Human
response to estrogen GO:0043627 232 0.033
glycosyl compound metabolic process GO:1901657 182 0.033
Human
positive regulation of rna metabolic process GO:0051254 203 0.032
regulation of apoptotic process GO:0042981 335 0.032
single organism catabolic process GO:0044712 283 0.032
Human
regulation of cellular amino acid metabolic process GO:0006521 2 0.032
positive regulation of phosphate metabolic process GO:0045937 262 0.032
positive regulation of signaling GO:0023056 270 0.031
protein complex assembly GO:0006461 263 0.031
regulation of rna biosynthetic process GO:2001141 381 0.031
response to oxygen levels GO:0070482 265 0.031
purine ribonucleotide metabolic process GO:0009150 227 0.031
Human
positive regulation of intracellular signal transduction GO:1902533 138 0.031
regulation of transcription dna templated GO:0006355 374 0.031
neuron projection development GO:0031175 273 0.031
cellular amine metabolic process GO:0044106 38 0.030
cell morphogenesis involved in differentiation GO:0000904 119 0.030
positive regulation of mesenchymal cell proliferation GO:0002053 4 0.030
regulation of establishment of planar polarity GO:0090175 2 0.030
cell motility GO:0048870 202 0.029
positive regulation of phosphorus metabolic process GO:0010562 262 0.029
intracellular transport GO:0046907 185 0.029
neuron development GO:0048666 286 0.029
regulation of cell projection organization GO:0031344 175 0.029
positive regulation of phosphorylation GO:0042327 177 0.029
response to nutrient GO:0007584 248 0.029
amine metabolic process GO:0009308 38 0.028
cation transport GO:0006812 382 0.028
organophosphate metabolic process GO:0019637 370 0.028
Human
macromolecule localization GO:0033036 252 0.028
Human
purine containing compound metabolic process GO:0072521 253 0.028
Human
cellular response to lipid GO:0071396 201 0.028
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.028
positive regulation of protein modification process GO:0031401 142 0.028
positive regulation of rna biosynthetic process GO:1902680 197 0.027
cell part morphogenesis GO:0032990 123 0.027
regulation of ion transport GO:0043269 245 0.027
cell morphogenesis GO:0000902 142 0.027
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.027
response to acid chemical GO:0001101 222 0.027
Human
regulation of mapk cascade GO:0043408 116 0.027
heart morphogenesis GO:0003007 3 0.026
transcription from rna polymerase ii promoter GO:0006366 252 0.026
establishment of protein localization GO:0045184 141 0.026
gastrulation GO:0007369 2 0.026
cell projection morphogenesis GO:0048858 123 0.026
response to hypoxia GO:0001666 231 0.026
positive regulation of apoptotic process GO:0043065 154 0.026
ribose phosphate metabolic process GO:0019693 235 0.026
Human
small gtpase mediated signal transduction GO:0007264 36 0.026
muscle tissue development GO:0060537 58 0.026
positive regulation of molecular function GO:0044093 230 0.026
response to decreased oxygen levels GO:0036293 237 0.025
multi organism reproductive process GO:0044703 262 0.025
positive regulation of multicellular organismal process GO:0051240 387 0.025
positive regulation of nucleic acid templated transcription GO:1903508 197 0.025
macromolecular complex subunit organization GO:0043933 339 0.025
response to growth factor GO:0070848 189 0.025
negative regulation of gene expression GO:0010629 199 0.025
regulation of response to stress GO:0080134 126 0.025
regulation of neuron differentiation GO:0045664 208 0.025
negative regulation of developmental process GO:0051093 125 0.025
positive regulation of cell communication GO:0010647 271 0.024
protein transport GO:0015031 132 0.024
negative regulation of metabolic process GO:0009892 331 0.024
Human
regeneration GO:0031099 163 0.024
cellular component morphogenesis GO:0032989 155 0.024
response to peptide hormone GO:0043434 278 0.024
multicellular organism reproduction GO:0032504 233 0.024
positive regulation of protein phosphorylation GO:0001934 135 0.024
cardiovascular system development GO:0072358 134 0.024
enzyme linked receptor protein signaling pathway GO:0007167 116 0.024
immune response GO:0006955 104 0.024
positive regulation of cellular component organization GO:0051130 200 0.023
regulation of locomotion GO:0040012 148 0.023
response to nutrient levels GO:0031667 370 0.023
protein oligomerization GO:0051259 191 0.023
protein localization GO:0008104 191 0.023
Human
cellular macromolecule localization GO:0070727 122 0.023
Human
renal system development GO:0072001 67 0.023
ribonucleotide metabolic process GO:0009259 231 0.023
Human
macromolecular complex assembly GO:0065003 273 0.022
apoptotic process GO:0006915 381 0.022
negative regulation of signaling GO:0023057 157 0.022
Human
multicellular organismal reproductive process GO:0048609 233 0.022
immune system process GO:0002376 204 0.022
cellular response to organic cyclic compound GO:0071407 202 0.022
ras protein signal transduction GO:0007265 29 0.022
anterior posterior pattern specification GO:0009952 1 0.022
negative regulation of cell communication GO:0010648 158 0.022
Human
biological adhesion GO:0022610 110 0.022
cellular protein localization GO:0034613 122 0.021
Human
positive regulation of cell differentiation GO:0045597 217 0.021
reproductive system development GO:0061458 128 0.021
regulation of neuron projection development GO:0010975 161 0.021
nucleobase containing small molecule metabolic process GO:0055086 316 0.021
Human
programmed cell death GO:0012501 392 0.021
establishment of tissue polarity GO:0007164 2 0.021
regulation of anatomical structure size GO:0090066 135 0.021
central nervous system development GO:0007417 311 0.021
reproductive structure development GO:0048608 128 0.021
nucleotide metabolic process GO:0009117 279 0.021
Human
response to estradiol GO:0032355 164 0.021
growth GO:0040007 165 0.021
Human
multi multicellular organism process GO:0044706 138 0.021
embryonic pattern specification GO:0009880 1 0.021
purine containing compound catabolic process GO:0072523 138 0.021
Human
positive regulation of transcription dna templated GO:0045893 197 0.020
purine ribonucleoside metabolic process GO:0046128 168 0.020
Human
nucleoside phosphate metabolic process GO:0006753 283 0.020
Human
purine nucleoside triphosphate catabolic process GO:0009146 122 0.020
Human
positive regulation of neurogenesis GO:0050769 165 0.020
head development GO:0060322 247 0.020
negative regulation of cell death GO:0060548 229 0.020
circulatory system development GO:0072359 134 0.019
mesoderm development GO:0007498 2 0.019
protein complex biogenesis GO:0070271 263 0.019
transmembrane transport GO:0055085 412 0.019
positive regulation of catalytic activity GO:0043085 184 0.019
regulation of nucleotide metabolic process GO:0006140 117 0.019
Human
response to other organism GO:0051707 220 0.019
aging GO:0007568 241 0.019
cellular catabolic process GO:0044248 295 0.019
Human
positive regulation of programmed cell death GO:0043068 157 0.019
cellular response to growth factor stimulus GO:0071363 162 0.019
organic substance catabolic process GO:1901575 316 0.019
Human
protein complex subunit organization GO:0071822 302 0.019
response to mechanical stimulus GO:0009612 134 0.019
regulation of immune system process GO:0002682 123 0.019
single organism organelle organization GO:1902589 180 0.019
regulation of cell development GO:0060284 263 0.019
response to biotic stimulus GO:0009607 226 0.019
cation homeostasis GO:0055080 195 0.019
wound healing GO:0042060 122 0.018
axonogenesis GO:0007409 71 0.018
negative regulation of cellular biosynthetic process GO:0031327 161 0.018
multicellular organismal signaling GO:0035637 44 0.018
negative regulation of nucleic acid templated transcription GO:1903507 117 0.018
regulation of anatomical structure morphogenesis GO:0022603 141 0.018
regulation of system process GO:0044057 208 0.018
muscle system process GO:0003012 115 0.018
negative regulation of multicellular organismal process GO:0051241 203 0.018
neuron projection morphogenesis GO:0048812 122 0.018
positive regulation of nervous system development GO:0051962 178 0.018
carbohydrate derivative catabolic process GO:1901136 147 0.018
Human
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.018
peptidyl amino acid modification GO:0018193 126 0.018
brain development GO:0007420 247 0.018
regulation of neuron death GO:1901214 115 0.018
cardiac chamber development GO:0003205 1 0.018
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.018
positive regulation of cell development GO:0010720 176 0.018
response to vitamin GO:0033273 131 0.018
positive regulation of cell death GO:0010942 184 0.018
response to inorganic substance GO:0010035 377 0.018
response to peptide GO:1901652 292 0.018
nucleoside metabolic process GO:0009116 179 0.018
Human
intracellular protein transport GO:0006886 79 0.018
ribonucleoside metabolic process GO:0009119 174 0.017
Human
regulation of cellular catabolic process GO:0031329 101 0.017
Human
response to wounding GO:0009611 254 0.017
cellular homeostasis GO:0019725 252 0.017
regulation of cellular localization GO:0060341 263 0.017
negative regulation of cell proliferation GO:0008285 119 0.017
Human
lipid metabolic process GO:0006629 283 0.017
positive regulation of catabolic process GO:0009896 78 0.017
Human
positive regulation of cellular amine metabolic process GO:0033240 3 0.017
chemical homeostasis GO:0048878 292 0.017
purine ribonucleoside triphosphate metabolic process GO:0009205 140 0.017
Human
regulation of mesenchymal cell proliferation GO:0010464 4 0.017
cellular response to organonitrogen compound GO:0071417 197 0.017
Human
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.017
regulation of catalytic activity GO:0050790 304 0.017
Human
reproduction GO:0000003 245 0.017
regulation of cell migration GO:0030334 128 0.017
purine ribonucleoside catabolic process GO:0046130 124 0.017
Human
ion transmembrane transport GO:0034220 365 0.017
cell cell signaling GO:0007267 335 0.017
vesicle mediated transport GO:0016192 181 0.017
regulation of catabolic process GO:0009894 113 0.016
Human
regulation of cellular component movement GO:0051270 150 0.016
axis specification GO:0009798 4 0.016
negative regulation of biosynthetic process GO:0009890 168 0.016
regulation of transferase activity GO:0051338 123 0.016
cellular response to external stimulus GO:0071496 118 0.016
developmental growth GO:0048589 100 0.016
organophosphate catabolic process GO:0046434 148 0.016
Human
cytoplasmic transport GO:0016482 115 0.016
ion homeostasis GO:0050801 212 0.016
signal transduction by phosphorylation GO:0023014 144 0.016
axon development GO:0061564 96 0.016
cell morphogenesis involved in neuron differentiation GO:0048667 106 0.015
homeostatic process GO:0042592 331 0.015
neurological system process GO:0050877 219 0.015
organ morphogenesis GO:0009887 75 0.015
gland development GO:0048732 155 0.015
negative regulation of rna biosynthetic process GO:1902679 118 0.015
response to glucocorticoid GO:0051384 223 0.015
cell adhesion GO:0007155 110 0.015
defense response GO:0006952 194 0.015
urogenital system development GO:0001655 78 0.015
negative regulation of programmed cell death GO:0043069 183 0.015
cardiac ventricle development GO:0003231 1 0.015
anatomical structure formation involved in morphogenesis GO:0048646 83 0.015
organonitrogen compound catabolic process GO:1901565 179 0.015
Human
action potential GO:0001508 54 0.015
rhythmic process GO:0048511 156 0.015
cellular nitrogen compound catabolic process GO:0044270 163 0.015
Human
heterocycle catabolic process GO:0046700 167 0.015
Human
cellular chemical homeostasis GO:0055082 247 0.015
neuron death GO:0070997 127 0.015
positive regulation of mapk cascade GO:0043410 92 0.015
tube development GO:0035295 89 0.015
positive regulation of transport GO:0051050 245 0.014
regulation of cell motility GO:2000145 131 0.014
mesenchymal cell proliferation GO:0010463 4 0.014
response to external biotic stimulus GO:0043207 221 0.014
response to purine containing compound GO:0014074 126 0.014
regulation of membrane potential GO:0042391 110 0.014
negative regulation of transcription dna templated GO:0045892 116 0.014
negative regulation of response to stimulus GO:0048585 155 0.014
Human
negative regulation of protein phosphorylation GO:0001933 44 0.014
inorganic cation transmembrane transport GO:0098662 202 0.014
metal ion transport GO:0030001 289 0.014
developmental process involved in reproduction GO:0003006 159 0.014
glycosyl compound catabolic process GO:1901658 126 0.014
Human
ribonucleoside triphosphate catabolic process GO:0009203 122 0.014
Human
cell cycle GO:0007049 101 0.014
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.014
Human
reactive oxygen species metabolic process GO:0072593 37 0.014
bmp signaling pathway GO:0030509 4 0.014
cellular response to alcohol GO:0097306 87 0.014
wnt signaling pathway planar cell polarity pathway GO:0060071 2 0.014
regulation of cellular component size GO:0032535 51 0.014
epithelium development GO:0060429 96 0.014
single organism cellular localization GO:1902580 102 0.014
ribonucleoside triphosphate metabolic process GO:0009199 141 0.014
Human
muscle contraction GO:0006936 88 0.014
mapk cascade GO:0000165 140 0.014
inorganic ion transmembrane transport GO:0098660 229 0.014
cell fate determination GO:0001709 2 0.013
regulation of cell morphogenesis involved in differentiation GO:0010769 72 0.013
secretion by cell GO:0032940 248 0.013
ribonucleoside catabolic process GO:0042454 126 0.013
Human
response to ketone GO:1901654 182 0.013
coenzyme metabolic process GO:0006732 86 0.013
response to carbohydrate GO:0009743 183 0.013
purine nucleotide metabolic process GO:0006163 229 0.013
Human
nucleotide catabolic process GO:0009166 139 0.013
Human
negative regulation of cellular component organization GO:0051129 83 0.013
cellular response to abiotic stimulus GO:0071214 85 0.013
negative regulation of protein metabolic process GO:0051248 114 0.013
regulation of canonical wnt signaling pathway GO:0060828 4 0.013
cellular cation homeostasis GO:0030003 180 0.013
ossification GO:0001503 70 0.013
regulation of cell morphogenesis GO:0022604 77 0.013
aromatic compound catabolic process GO:0019439 168 0.012
Human
positive regulation of purine nucleotide metabolic process GO:1900544 91 0.012
dna metabolic process GO:0006259 96 0.012
synaptic growth at neuromuscular junction GO:0051124 1 0.012
organ formation GO:0048645 3 0.012
non canonical wnt signaling pathway GO:0035567 3 0.012
synaptic transmission GO:0007268 235 0.012
regulation of kinase activity GO:0043549 117 0.012
negative regulation of phosphate metabolic process GO:0045936 80 0.012
Human
nucleoside catabolic process GO:0009164 126 0.012
Human
blood circulation GO:0008015 183 0.012
regulation of neuron apoptotic process GO:0043523 83 0.012
response to metal ion GO:0010038 253 0.012
guanosine containing compound metabolic process GO:1901068 74 0.012
Human
negative regulation of cellular protein metabolic process GO:0032269 106 0.012
anion transport GO:0006820 178 0.012
single organism cell adhesion GO:0098602 46 0.012
purine nucleoside triphosphate metabolic process GO:0009144 141 0.012
Human
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 85 0.012
circulatory system process GO:0003013 183 0.012
ribonucleotide catabolic process GO:0009261 136 0.012
Human
positive regulation of cell projection organization GO:0031346 111 0.012
dephosphorylation GO:0016311 98 0.012
negative regulation of phosphorus metabolic process GO:0010563 80 0.012
Human
oxidation reduction process GO:0055114 304 0.012
regulation of stem cell differentiation GO:2000736 2 0.012
regulation of cellular component biogenesis GO:0044087 86 0.012
divalent inorganic cation transport GO:0072511 134 0.012
cellular response to hormone stimulus GO:0032870 247 0.012
response to oxidative stress GO:0006979 186 0.012
cellular response to nitrogen compound GO:1901699 210 0.012
Human
divalent metal ion transport GO:0070838 132 0.012
establishment of planar polarity GO:0001736 1 0.012
morphogenesis of a polarized epithelium GO:0001738 1 0.012
regulation of vesicle mediated transport GO:0060627 81 0.012
regulation of hydrolase activity GO:0051336 143 0.012
Human
negative regulation of canonical wnt signaling pathway GO:0090090 4 0.012
muscle structure development GO:0061061 87 0.012
secretion GO:0046903 307 0.012
salivary gland development GO:0007431 3 0.012
gamete generation GO:0007276 124 0.012
membrane organization GO:0061024 94 0.012
negative regulation of apoptotic process GO:0043066 181 0.012
cellular response to biotic stimulus GO:0071216 59 0.012
positive regulation of purine nucleotide catabolic process GO:0033123 53 0.012
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090101 2 0.012
female pregnancy GO:0007565 122 0.012
sexual reproduction GO:0019953 148 0.011
actin filament based process GO:0030029 86 0.011
metal ion homeostasis GO:0055065 186 0.011
sex differentiation GO:0007548 113 0.011
negative regulation of innate immune response GO:0045824 4 0.011
positive regulation of cellular catabolic process GO:0031331 71 0.011
Human
regulation of blood circulation GO:1903522 110 0.011
heart development GO:0007507 72 0.011
organophosphate biosynthetic process GO:0090407 143 0.011
formation of primary germ layer GO:0001704 1 0.011
cellular response to steroid hormone stimulus GO:0071383 93 0.011
monocarboxylic acid metabolic process GO:0032787 152 0.011
regulation of proteasomal protein catabolic process GO:0061136 4 0.011
nucleobase containing compound catabolic process GO:0034655 152 0.011
Human
striated muscle tissue development GO:0014706 58 0.011
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.011
calcium ion transport GO:0006816 131 0.011
response to camp GO:0051591 91 0.011
reactive nitrogen species metabolic process GO:2001057 1 0.011
positive regulation of neuron differentiation GO:0045666 126 0.011
divalent inorganic cation homeostasis GO:0072507 165 0.011
monovalent inorganic cation transport GO:0015672 172 0.011
response to monosaccharide GO:0034284 159 0.011
nucleoside triphosphate metabolic process GO:0009141 144 0.011
Human
cellular response to oxidative stress GO:0034599 76 0.011
response to corticosteroid GO:0031960 235 0.011
purine nucleoside metabolic process GO:0042278 169 0.011
Human
sensory organ development GO:0007423 74 0.011
neuronal action potential GO:0019228 35 0.011
response to hexose GO:0009746 144 0.011
salivary gland morphogenesis GO:0007435 1 0.011
positive regulation of cell motility GO:2000147 97 0.011
regulation of reactive oxygen species metabolic process GO:2000377 26 0.011
chemotaxis GO:0006935 66 0.011
cellular divalent inorganic cation homeostasis GO:0072503 162 0.011
organic cyclic compound catabolic process GO:1901361 175 0.010
Human
spindle organization GO:0007051 2 0.010
cation transmembrane transport GO:0098655 263 0.010
negative regulation of transport GO:0051051 136 0.010
cellular response to endogenous stimulus GO:0071495 377 0.010
Human
protein localization to organelle GO:0033365 57 0.010
Human
response to toxic substance GO:0009636 133 0.010
regulation of tube size GO:0035150 89 0.010
purine ribonucleoside triphosphate catabolic process GO:0009207 122 0.010
Human
embryonic axis specification GO:0000578 1 0.010
regulation of muscle system process GO:0090257 79 0.010
negative regulation of molecular function GO:0044092 133 0.010
Human
proteolysis GO:0006508 175 0.010
adult locomotory behavior GO:0008344 4 0.010
purine ribonucleotide catabolic process GO:0009154 136 0.010
Human
regulation of cell adhesion GO:0030155 52 0.010

Sh3bp4 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.017
nervous system disease DOID:863 0 0.017
disease of metabolism DOID:0014667 0 0.014
inherited metabolic disorder DOID:655 0 0.014