Rattus norvegicus

0 known processes

Sh3bp5

SH3-domain binding protein 5 (BTK-associated)

(Aliases: Sab,Vesp18,SH3BP-5)

Sh3bp5 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
anatomical structure morphogenesis GO:0009653 298 0.103
regulation of transcription dna templated GO:0006355 374 0.102
transcription dna templated GO:0006351 377 0.086
nucleic acid templated transcription GO:0097659 379 0.076
apoptotic process GO:0006915 381 0.068
regulation of rna metabolic process GO:0051252 391 0.068
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.067
positive regulation of multicellular organismal process GO:0051240 387 0.067
regulation of apoptotic process GO:0042981 335 0.066
regulation of rna biosynthetic process GO:2001141 381 0.066
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.064
protein phosphorylation GO:0006468 345 0.063
Human Mouse
cellular amino acid metabolic process GO:0006520 107 0.061
negative regulation of cell death GO:0060548 229 0.060
neuron differentiation GO:0030182 368 0.058
rna biosynthetic process GO:0032774 380 0.057
regulation of locomotion GO:0040012 148 0.054
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.052
negative regulation of signaling GO:0023057 157 0.050
regulation of multicellular organismal development GO:2000026 376 0.050
regulation of programmed cell death GO:0043067 341 0.049
response to wounding GO:0009611 254 0.047
regulation of protein modification process GO:0031399 194 0.047
Human Mouse
rna metabolic process GO:0016070 406 0.047
neuron development GO:0048666 286 0.045
regulation of nucleic acid templated transcription GO:1903506 380 0.044
negative regulation of cellular metabolic process GO:0031324 281 0.043
Human Mouse
regulation of neuron differentiation GO:0045664 208 0.042
transcription from rna polymerase ii promoter GO:0006366 252 0.041
positive regulation of cell migration GO:0030335 96 0.041
regulation of cell migration GO:0030334 128 0.040
neuron projection development GO:0031175 273 0.040
regulation of cell differentiation GO:0045595 320 0.038
programmed cell death GO:0012501 392 0.037
carboxylic acid metabolic process GO:0019752 289 0.037
positive regulation of biosynthetic process GO:0009891 319 0.037
positive regulation of developmental process GO:0051094 283 0.036
positive regulation of response to stimulus GO:0048584 285 0.036
regulation of catalytic activity GO:0050790 304 0.034
Human Mouse
cellular response to oxygen containing compound GO:1901701 386 0.034
regeneration GO:0031099 163 0.034
regulation of molecular function GO:0065009 398 0.033
Human Mouse
regulation of intracellular signal transduction GO:1902531 218 0.033
cellular nitrogen compound catabolic process GO:0044270 163 0.033
regulation of signal transduction GO:0009966 318 0.033
neuron projection morphogenesis GO:0048812 122 0.033
cellular amine metabolic process GO:0044106 38 0.033
cellular ketone metabolic process GO:0042180 51 0.032
neuron apoptotic process GO:0051402 88 0.032
oxoacid metabolic process GO:0043436 290 0.032
regulation of nervous system development GO:0051960 264 0.032
cellular catabolic process GO:0044248 295 0.032
carbohydrate derivative metabolic process GO:1901135 346 0.032
regulation of protein phosphorylation GO:0001932 183 0.032
Human Mouse
positive regulation of phosphorus metabolic process GO:0010562 262 0.031
nucleoside phosphate metabolic process GO:0006753 283 0.031
positive regulation of gene expression GO:0010628 244 0.031
regulation of phosphorylation GO:0042325 248 0.031
Human Mouse
positive regulation of cellular biosynthetic process GO:0031328 295 0.031
negative regulation of apoptotic process GO:0043066 181 0.031
organic acid metabolic process GO:0006082 292 0.030
catabolic process GO:0009056 351 0.030
regulation of cellular amino acid metabolic process GO:0006521 2 0.030
cellular response to stress GO:0033554 269 0.030
amine metabolic process GO:0009308 38 0.030
cellular response to endogenous stimulus GO:0071495 377 0.030
cell projection organization GO:0030030 302 0.029
homeostatic process GO:0042592 331 0.029
regulation of cellular component movement GO:0051270 150 0.029
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 85 0.029
response to growth factor GO:0070848 189 0.028
ribose phosphate metabolic process GO:0019693 235 0.028
positive regulation of molecular function GO:0044093 230 0.028
response to inorganic substance GO:0010035 377 0.028
organophosphate metabolic process GO:0019637 370 0.028
cell migration GO:0016477 197 0.028
regulation of phosphorus metabolic process GO:0051174 349 0.028
Human Mouse
response to oxygen levels GO:0070482 265 0.028
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.028
positive regulation of cell motility GO:2000147 97 0.027
tissue development GO:0009888 252 0.027
single organism catabolic process GO:0044712 283 0.027
regulation of cell proliferation GO:0042127 359 0.027
cell type specific apoptotic process GO:0097285 134 0.027
positive regulation of neurogenesis GO:0050769 165 0.027
organic substance catabolic process GO:1901575 316 0.027
lipid metabolic process GO:0006629 283 0.026
negative regulation of programmed cell death GO:0043069 183 0.026
cellular component movement GO:0006928 248 0.026
purine nucleoside triphosphate catabolic process GO:0009146 122 0.026
central nervous system development GO:0007417 311 0.026
nucleotide metabolic process GO:0009117 279 0.026
single organism reproductive process GO:0044702 297 0.026
ribonucleotide metabolic process GO:0009259 231 0.026
regulation of system process GO:0044057 208 0.026
response to decreased oxygen levels GO:0036293 237 0.025
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.025
positive regulation of cell differentiation GO:0045597 217 0.025
regulation of cell development GO:0060284 263 0.025
cellular component morphogenesis GO:0032989 155 0.025
positive regulation of rna biosynthetic process GO:1902680 197 0.025
heart contraction GO:0060047 57 0.025
response to peptide hormone GO:0043434 278 0.025
response to metal ion GO:0010038 253 0.025
regulation of cellular amine metabolic process GO:0033238 8 0.025
regulation of neuron projection development GO:0010975 161 0.025
regulation of cellular ketone metabolic process GO:0010565 27 0.024
positive regulation of phosphate metabolic process GO:0045937 262 0.024
circulatory system process GO:0003013 183 0.024
organic cyclic compound catabolic process GO:1901361 175 0.024
enzyme linked receptor protein signaling pathway GO:0007167 116 0.024
regulation of membrane potential GO:0042391 110 0.024
response to nutrient levels GO:0031667 370 0.024
developmental growth GO:0048589 100 0.024
regulation of response to stress GO:0080134 126 0.024
cellular response to organic cyclic compound GO:0071407 202 0.023
positive regulation of cellular component movement GO:0051272 102 0.023
locomotion GO:0040011 237 0.023
ribonucleoside metabolic process GO:0009119 174 0.023
intracellular signal transduction GO:0035556 314 0.023
Human
positive regulation of cell communication GO:0010647 271 0.023
heterocycle catabolic process GO:0046700 167 0.023
ras protein signal transduction GO:0007265 29 0.023
nucleoside catabolic process GO:0009164 126 0.023
response to carbohydrate GO:0009743 183 0.023
ribonucleoside catabolic process GO:0042454 126 0.022
cell projection morphogenesis GO:0048858 123 0.022
negative regulation of metabolic process GO:0009892 331 0.022
Human Mouse
neuron death GO:0070997 127 0.022
positive regulation of cellular amine metabolic process GO:0033240 3 0.022
muscle system process GO:0003012 115 0.022
positive regulation of signaling GO:0023056 270 0.022
positive regulation of nervous system development GO:0051962 178 0.022
regulation of cellular protein metabolic process GO:0032268 267 0.022
Human Mouse
regulation of phosphate metabolic process GO:0019220 349 0.021
Human Mouse
cellular lipid metabolic process GO:0044255 208 0.021
regulation of anatomical structure morphogenesis GO:0022603 141 0.021
positive regulation of cell proliferation GO:0008284 249 0.021
positive regulation of nucleic acid templated transcription GO:1903508 197 0.021
purine containing compound metabolic process GO:0072521 253 0.021
response to extracellular stimulus GO:0009991 380 0.021
ribonucleoside triphosphate catabolic process GO:0009203 122 0.021
positive regulation of neuron projection development GO:0010976 99 0.020
positive regulation of phosphorylation GO:0042327 177 0.020
purine containing compound catabolic process GO:0072523 138 0.020
aromatic compound catabolic process GO:0019439 168 0.020
regulation of cellular component organization GO:0051128 368 0.020
establishment of tissue polarity GO:0007164 2 0.020
regulation of protein metabolic process GO:0051246 289 0.020
Human Mouse
negative regulation of cell communication GO:0010648 158 0.020
cell part morphogenesis GO:0032990 123 0.020
regulation of transferase activity GO:0051338 123 0.020
Human Mouse
negative regulation of response to stimulus GO:0048585 155 0.020
vesicle mediated transport GO:0016192 181 0.019
regulation of hormone levels GO:0010817 187 0.019
positive regulation of protein modification process GO:0031401 142 0.019
purine ribonucleoside triphosphate catabolic process GO:0009207 122 0.019
cellular response to growth factor stimulus GO:0071363 162 0.019
regulation of catabolic process GO:0009894 113 0.019
response to glucose GO:0009749 136 0.019
chemical homeostasis GO:0048878 292 0.019
positive regulation of neuron differentiation GO:0045666 126 0.019
purine ribonucleoside metabolic process GO:0046128 168 0.019
embryonic pattern specification GO:0009880 1 0.019
head development GO:0060322 247 0.019
positive regulation of intracellular signal transduction GO:1902533 138 0.019
organonitrogen compound catabolic process GO:1901565 179 0.019
ion transmembrane transport GO:0034220 365 0.019
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.018
positive regulation of cell development GO:0010720 176 0.018
positive regulation of transcription dna templated GO:0045893 197 0.018
regulation of cell projection organization GO:0031344 175 0.018
regulation of cell motility GO:2000145 131 0.018
localization of cell GO:0051674 202 0.018
multicellular organismal reproductive process GO:0048609 233 0.018
positive regulation of axon guidance GO:1902669 3 0.018
purine nucleoside catabolic process GO:0006152 124 0.018
single organism biosynthetic process GO:0044711 342 0.018
nitrogen compound transport GO:0071705 229 0.018
cellular chemical homeostasis GO:0055082 247 0.018
response to hypoxia GO:0001666 231 0.018
regulation of protein kinase activity GO:0045859 105 0.018
Human Mouse
growth GO:0040007 165 0.018
regulation of neurogenesis GO:0050767 247 0.017
ion homeostasis GO:0050801 212 0.017
response to nutrient GO:0007584 248 0.017
small gtpase mediated signal transduction GO:0007264 36 0.017
reproduction GO:0000003 245 0.017
purine nucleotide metabolic process GO:0006163 229 0.017
ribonucleoside triphosphate metabolic process GO:0009199 141 0.017
muscle structure development GO:0061061 87 0.017
transmembrane transport GO:0055085 412 0.017
response to acid chemical GO:0001101 222 0.017
nucleoside phosphate catabolic process GO:1901292 140 0.017
wound healing GO:0042060 122 0.017
negative regulation of macromolecule metabolic process GO:0010605 260 0.017
Human Mouse
nucleobase containing small molecule metabolic process GO:0055086 316 0.016
reproductive process GO:0022414 372 0.016
positive regulation of tor signaling GO:0032008 2 0.016
negative regulation of developmental process GO:0051093 125 0.016
cellular homeostasis GO:0019725 252 0.016
regulation of immune system process GO:0002682 123 0.016
cell cell signaling GO:0007267 335 0.016
regulation of secretion by cell GO:1903530 208 0.016
purine nucleoside triphosphate metabolic process GO:0009144 141 0.016
regulation of response to external stimulus GO:0032101 106 0.016
anterior posterior pattern specification GO:0009952 1 0.016
regulation of blood circulation GO:1903522 110 0.016
purine ribonucleoside catabolic process GO:0046130 124 0.016
positive regulation of rna metabolic process GO:0051254 203 0.016
brain development GO:0007420 247 0.016
multi organism reproductive process GO:0044703 262 0.016
response to reactive oxygen species GO:0000302 120 0.016
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.016
regulation of neuron apoptotic process GO:0043523 83 0.016
purine ribonucleotide catabolic process GO:0009154 136 0.016
axis specification GO:0009798 4 0.015
cellular response to organonitrogen compound GO:0071417 197 0.015
purine nucleoside metabolic process GO:0042278 169 0.015
cell morphogenesis involved in differentiation GO:0000904 119 0.015
single organism organelle organization GO:1902589 180 0.015
response to hexose GO:0009746 144 0.015
response to bacterium GO:0009617 200 0.015
positive regulation of protein phosphorylation GO:0001934 135 0.015
positive regulation of endothelial cell migration GO:0010595 4 0.015
carbohydrate derivative catabolic process GO:1901136 147 0.015
regulation of hydrolase activity GO:0051336 143 0.015
cell motility GO:0048870 202 0.015
cation transport GO:0006812 382 0.015
action potential GO:0001508 54 0.015
glycosyl compound catabolic process GO:1901658 126 0.015
regulation of canonical wnt signaling pathway GO:0060828 4 0.015
regulation of synaptic transmission GO:0050804 141 0.015
single organism intracellular transport GO:1902582 166 0.015
positive regulation of cellular component organization GO:0051130 200 0.015
positive regulation of apoptotic process GO:0043065 154 0.015
synaptic transmission GO:0007268 235 0.015
positive regulation of immune system process GO:0002684 90 0.015
positive regulation of ion transport GO:0043270 94 0.014
organophosphate catabolic process GO:0046434 148 0.014
positive regulation of catalytic activity GO:0043085 184 0.014
regulation of cell morphogenesis involved in differentiation GO:0010769 72 0.014
positive regulation of protein metabolic process GO:0051247 178 0.014
positive regulation of cell death GO:0010942 184 0.014
negative regulation of protein metabolic process GO:0051248 114 0.014
Human Mouse
response to monosaccharide GO:0034284 159 0.014
negative regulation of gene expression GO:0010629 199 0.014
regulation of kinase activity GO:0043549 117 0.014
Human Mouse
regulation of anatomical structure size GO:0090066 135 0.014
chromosome segregation GO:0007059 2 0.014
regulation of ion transport GO:0043269 245 0.014
nucleobase containing compound catabolic process GO:0034655 152 0.014
purine ribonucleotide metabolic process GO:0009150 227 0.014
response to mechanical stimulus GO:0009612 134 0.014
nucleoside metabolic process GO:0009116 179 0.014
cellular component assembly GO:0022607 360 0.014
negative regulation of multicellular organismal process GO:0051241 203 0.014
cell morphogenesis involved in neuron differentiation GO:0048667 106 0.014
response to estrogen GO:0043627 232 0.014
positive regulation of transferase activity GO:0051347 81 0.014
blood circulation GO:0008015 183 0.014
cellular response to nitrogen compound GO:1901699 210 0.014
carboxylic acid transport GO:0046942 115 0.013
negative regulation of transport GO:0051051 136 0.013
heart development GO:0007507 72 0.013
negative regulation of cell differentiation GO:0045596 99 0.013
heart process GO:0003015 57 0.013
cell morphogenesis GO:0000902 142 0.013
regulation of nucleoside metabolic process GO:0009118 66 0.013
nucleotide catabolic process GO:0009166 139 0.013
organ morphogenesis GO:0009887 75 0.013
positive regulation of kinase activity GO:0033674 77 0.013
amide transport GO:0042886 105 0.013
heart morphogenesis GO:0003007 3 0.013
positive regulation of cell projection organization GO:0031346 111 0.013
gland development GO:0048732 155 0.013
multicellular organism reproduction GO:0032504 233 0.013
forebrain development GO:0030900 98 0.013
positive regulation of signal transduction GO:0009967 175 0.013
cation transmembrane transport GO:0098655 263 0.013
carbohydrate derivative biosynthetic process GO:1901137 124 0.013
macromolecular complex subunit organization GO:0043933 339 0.013
single organism carbohydrate metabolic process GO:0044723 118 0.013
positive regulation of cellular protein metabolic process GO:0032270 167 0.013
cardiac chamber development GO:0003205 1 0.013
cellular response to hormone stimulus GO:0032870 247 0.013
organic anion transport GO:0015711 132 0.013
cellular response to lipid GO:0071396 201 0.013
positive regulation of mapk cascade GO:0043410 92 0.013
nucleoside triphosphate catabolic process GO:0009143 123 0.012
organonitrogen compound biosynthetic process GO:1901566 167 0.012
response to peptide GO:1901652 292 0.012
metal ion transport GO:0030001 289 0.012
response to lipopolysaccharide GO:0032496 191 0.012
response to ketone GO:1901654 182 0.012
cellular ion homeostasis GO:0006873 184 0.012
signal transduction by phosphorylation GO:0023014 144 0.012
circulatory system development GO:0072359 134 0.012
response to ethanol GO:0045471 162 0.012
response to oxidative stress GO:0006979 186 0.012
regulation of cellular localization GO:0060341 263 0.012
organelle organization GO:0006996 266 0.012
cellular calcium ion homeostasis GO:0006874 160 0.012
purine ribonucleoside triphosphate metabolic process GO:0009205 140 0.012
nucleoside triphosphate metabolic process GO:0009141 144 0.012
negative regulation of cellular biosynthetic process GO:0031327 161 0.012
positive regulation of nucleotide metabolic process GO:0045981 91 0.012
peptide transport GO:0015833 97 0.012
sexual reproduction GO:0019953 148 0.012
response to calcium ion GO:0051592 59 0.012
spermatogenesis GO:0007283 99 0.012
calcium ion homeostasis GO:0055074 162 0.012
negative regulation of cellular protein metabolic process GO:0032269 106 0.011
Human Mouse
positive regulation of locomotion GO:0040017 102 0.011
cellular component biogenesis GO:0044085 368 0.011
positive regulation of mesenchymal cell proliferation GO:0002053 4 0.011
salivary gland morphogenesis GO:0007435 1 0.011
negative regulation of rna metabolic process GO:0051253 123 0.011
secretion by cell GO:0032940 248 0.011
dendrite development GO:0016358 72 0.011
macromolecule localization GO:0033036 252 0.011
defense response GO:0006952 194 0.011
negative regulation of extrinsic apoptotic signaling pathway GO:2001237 4 0.011
synaptic growth at neuromuscular junction GO:0051124 1 0.011
response to other organism GO:0051707 220 0.011
cell growth GO:0016049 104 0.011
macromolecular complex assembly GO:0065003 273 0.011
anion transport GO:0006820 178 0.011
protein oligomerization GO:0051259 191 0.011
neurological system process GO:0050877 219 0.011
metal ion homeostasis GO:0055065 186 0.011
rhythmic process GO:0048511 156 0.011
regulation of heart contraction GO:0008016 48 0.011
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.011
response to hydrogen peroxide GO:0042542 89 0.011
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.011
positive regulation of cytosolic calcium ion concentration GO:0007204 122 0.011
neuronal action potential GO:0019228 35 0.010
regulation of mapk cascade GO:0043408 116 0.010
telencephalon development GO:0021537 62 0.010
response to glucocorticoid GO:0051384 223 0.010
cellular divalent inorganic cation homeostasis GO:0072503 162 0.010
regulation of cell growth GO:0001558 85 0.010
protein complex biogenesis GO:0070271 263 0.010
male gamete generation GO:0048232 99 0.010
response to radiation GO:0009314 137 0.010
negative regulation of biosynthetic process GO:0009890 168 0.010
regulation of neuron death GO:1901214 115 0.010
gastrulation GO:0007369 2 0.010
multicellular organismal signaling GO:0035637 44 0.010
response to biotic stimulus GO:0009607 226 0.010
regulation of peptide transport GO:0090087 87 0.010
negative regulation of molecular function GO:0044092 133 0.010
Human Mouse
actin filament based process GO:0030029 86 0.010
response to fatty acid GO:0070542 65 0.010
response to corticosteroid GO:0031960 235 0.010
axonogenesis GO:0007409 71 0.010
regulation of dendrite development GO:0050773 59 0.010

Sh3bp5 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
musculoskeletal system disease DOID:17 0 0.014
disease of anatomical entity DOID:7 0 0.014
disease of metabolism DOID:0014667 0 0.014
muscular disease DOID:0080000 0 0.011
myopathy DOID:423 0 0.011
muscle tissue disease DOID:66 0 0.011
inherited metabolic disorder DOID:655 0 0.011
nervous system disease DOID:863 0 0.011