Rattus norvegicus

20 known processes

Eif4g1

eukaryotic translation initiation factor 4 gamma, 1

Eif4g1 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
rna biosynthetic process GO:0032774 380 0.101
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.078
regulation of transcription dna templated GO:0006355 374 0.077
nucleic acid templated transcription GO:0097659 379 0.057
regulation of nucleic acid templated transcription GO:1903506 380 0.052
neuron differentiation GO:0030182 368 0.052
regulation of rna metabolic process GO:0051252 391 0.052
rna metabolic process GO:0016070 406 0.048
transcription from rna polymerase ii promoter GO:0006366 252 0.038
response to extracellular stimulus GO:0009991 380 0.036
response to nutrient levels GO:0031667 370 0.034
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.031
cellular homeostasis GO:0019725 252 0.031
negative regulation of gene expression GO:0010629 199 0.031
positive regulation of gene expression GO:0010628 244 0.031
response to nutrient GO:0007584 248 0.030
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.030
regulation of rna biosynthetic process GO:2001141 381 0.029
single organism catabolic process GO:0044712 283 0.028
positive regulation of signaling GO:0023056 270 0.027
regulation of multicellular organismal development GO:2000026 376 0.027
positive regulation of nucleic acid templated transcription GO:1903508 197 0.027
positive regulation of biosynthetic process GO:0009891 319 0.027
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.026
single organism reproductive process GO:0044702 297 0.026
organophosphate catabolic process GO:0046434 148 0.026
cellular response to organonitrogen compound GO:0071417 197 0.026
carbohydrate derivative metabolic process GO:1901135 346 0.026
cellular response to stress GO:0033554 269 0.026
protein complex subunit organization GO:0071822 302 0.025
secretion GO:0046903 307 0.025
macromolecular complex assembly GO:0065003 273 0.025
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.024
growth GO:0040007 165 0.024
negative regulation of cell development GO:0010721 82 0.024
anion transport GO:0006820 178 0.024
chromatin assembly or disassembly GO:0006333 1 0.023
positive regulation of rna biosynthetic process GO:1902680 197 0.023
regulation of synaptic transmission GO:0050804 141 0.023
multi organism reproductive process GO:0044703 262 0.023
regulation of phosphate metabolic process GO:0019220 349 0.022
oxidation reduction process GO:0055114 304 0.022
negative regulation of developmental process GO:0051093 125 0.022
small gtpase mediated signal transduction GO:0007264 36 0.022
single organism carbohydrate metabolic process GO:0044723 118 0.022
negative regulation of rna metabolic process GO:0051253 123 0.022
positive regulation of cellular biosynthetic process GO:0031328 295 0.022
regulation of cell development GO:0060284 263 0.022
transcription dna templated GO:0006351 377 0.021
negative regulation of transcription from rna polymerase ii promoter GO:0000122 75 0.021
multicellular organism reproduction GO:0032504 233 0.021
response to vitamin GO:0033273 131 0.021
negative regulation of cellular biosynthetic process GO:0031327 161 0.020
negative regulation of metabolic process GO:0009892 331 0.020
cellular component biogenesis GO:0044085 368 0.020
purine nucleoside monophosphate metabolic process GO:0009126 84 0.020
multicellular organism growth GO:0035264 1 0.020
chemical homeostasis GO:0048878 292 0.020
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.020
positive regulation of phosphorus metabolic process GO:0010562 262 0.020
positive regulation of rna metabolic process GO:0051254 203 0.020
nucleoside phosphate metabolic process GO:0006753 283 0.019
cellular response to oxygen containing compound GO:1901701 386 0.019
regulation of phosphorus metabolic process GO:0051174 349 0.019
ribose phosphate metabolic process GO:0019693 235 0.019
organophosphate metabolic process GO:0019637 370 0.019
positive regulation of multicellular organismal process GO:0051240 387 0.018
negative regulation of rna biosynthetic process GO:1902679 118 0.018
cell cell signaling GO:0007267 335 0.018
protein oligomerization GO:0051259 191 0.018
regulation of cell proliferation GO:0042127 359 0.018
cellular response to nitrogen compound GO:1901699 210 0.018
positive regulation of developmental process GO:0051094 283 0.018
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.017
regulation of cell differentiation GO:0045595 320 0.017
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.017
protein complex assembly GO:0006461 263 0.017
secretion by cell GO:0032940 248 0.017
heart morphogenesis GO:0003007 3 0.017
cellular amine metabolic process GO:0044106 38 0.017
anatomical structure morphogenesis GO:0009653 298 0.017
protein complex biogenesis GO:0070271 263 0.017
heterocycle catabolic process GO:0046700 167 0.017
ion homeostasis GO:0050801 212 0.017
regulation of cellular amino acid metabolic process GO:0006521 2 0.017
establishment of protein localization GO:0045184 141 0.017
response to inorganic substance GO:0010035 377 0.017
cellular chemical homeostasis GO:0055082 247 0.017
rhythmic process GO:0048511 156 0.017
nucleotide metabolic process GO:0009117 279 0.016
ion transmembrane transport GO:0034220 365 0.016
regulation of protein phosphorylation GO:0001932 183 0.016
gliogenesis GO:0042063 93 0.016
intracellular transport GO:0046907 185 0.016
embryonic pattern specification GO:0009880 1 0.016
regulation of catalytic activity GO:0050790 304 0.016
carboxylic acid metabolic process GO:0019752 289 0.015
multicellular organismal signaling GO:0035637 44 0.015
regulation of stem cell differentiation GO:2000736 2 0.015
anion transmembrane transport GO:0098656 77 0.015
organic substance catabolic process GO:1901575 316 0.015
single organism intracellular transport GO:1902582 166 0.015
multicellular organismal reproductive process GO:0048609 233 0.015
dna metabolic process GO:0006259 96 0.015
negative regulation of nervous system development GO:0051961 79 0.015
ras protein signal transduction GO:0007265 29 0.015
cellular ketone metabolic process GO:0042180 51 0.015
cellular amino acid metabolic process GO:0006520 107 0.015
purine ribonucleoside monophosphate metabolic process GO:0009167 84 0.015
ribonucleotide metabolic process GO:0009259 231 0.015
amine metabolic process GO:0009308 38 0.014
purine nucleotide metabolic process GO:0006163 229 0.014
localization of cell GO:0051674 202 0.014
organelle organization GO:0006996 266 0.014
negative regulation of transcription dna templated GO:0045892 116 0.014
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.014
locomotion GO:0040011 237 0.014
positive regulation of transcription dna templated GO:0045893 197 0.014
cell morphogenesis involved in differentiation GO:0000904 119 0.014
positive regulation of nervous system development GO:0051962 178 0.014
tissue development GO:0009888 252 0.014
regulation of cellular component organization GO:0051128 368 0.014
transmission of nerve impulse GO:0019226 42 0.014
carbohydrate derivative biosynthetic process GO:1901137 124 0.014
glycosyl compound metabolic process GO:1901657 182 0.014
nucleoside monophosphate metabolic process GO:0009123 93 0.013
organic acid metabolic process GO:0006082 292 0.013
nucleoside metabolic process GO:0009116 179 0.013
cellular divalent inorganic cation homeostasis GO:0072503 162 0.013
positive regulation of cell communication GO:0010647 271 0.013
oxoacid metabolic process GO:0043436 290 0.013
circulatory system process GO:0003013 183 0.013
regulation of cell motility GO:2000145 131 0.013
circadian rhythm GO:0007623 88 0.013
response to purine containing compound GO:0014074 126 0.013
catabolic process GO:0009056 351 0.013
cellular macromolecule localization GO:0070727 122 0.013
sexual reproduction GO:0019953 148 0.013
negative regulation of mitotic cell cycle phase transition GO:1901991 3 0.013
macromolecular complex subunit organization GO:0043933 339 0.013
regulation of nervous system development GO:0051960 264 0.013
cellular component assembly GO:0022607 360 0.013
reactive oxygen species metabolic process GO:0072593 37 0.013
regulation of growth GO:0040008 105 0.013
homeostatic process GO:0042592 331 0.013
neuronal action potential GO:0019228 35 0.013
response to bacterium GO:0009617 200 0.012
regulation of cellular amine metabolic process GO:0033238 8 0.012
reactive oxygen species biosynthetic process GO:1903409 8 0.012
positive regulation of cell proliferation GO:0008284 249 0.012
response to growth factor GO:0070848 189 0.012
ribonucleoside metabolic process GO:0009119 174 0.012
negative regulation of cell cycle phase transition GO:1901988 4 0.012
axon development GO:0061564 96 0.012
purine containing compound metabolic process GO:0072521 253 0.012
mechanoreceptor differentiation GO:0042490 2 0.012
cellular response to growth factor stimulus GO:0071363 162 0.012
cell morphogenesis involved in neuron differentiation GO:0048667 106 0.012
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.012
cellular cation homeostasis GO:0030003 180 0.012
lymphocyte activation involved in immune response GO:0002285 3 0.012
regulation of smooth muscle cell proliferation GO:0048660 75 0.012
chromosome segregation GO:0007059 2 0.012
neuron development GO:0048666 286 0.012
regulation of secretion GO:0051046 224 0.011
lipid storage GO:0019915 1 0.011
negative regulation of cellular metabolic process GO:0031324 281 0.011
response to metal ion GO:0010038 253 0.011
rho protein signal transduction GO:0007266 11 0.011
ribonucleotide biosynthetic process GO:0009260 85 0.011
central nervous system development GO:0007417 311 0.011
nucleobase containing small molecule metabolic process GO:0055086 316 0.011
negative regulation of nephron tubule epithelial cell differentiation GO:0072183 1 0.011
ribonucleoside triphosphate metabolic process GO:0009199 141 0.011
reproductive system development GO:0061458 128 0.011
nucleoside triphosphate metabolic process GO:0009141 144 0.011
negative regulation of biosynthetic process GO:0009890 168 0.011
limb morphogenesis GO:0035108 4 0.011
peptide transport GO:0015833 97 0.011
purine nucleoside metabolic process GO:0042278 169 0.011
somatic stem cell maintenance GO:0035019 2 0.011
cellular nitrogen compound catabolic process GO:0044270 163 0.011
reproduction GO:0000003 245 0.011
positive regulation of cellular amine metabolic process GO:0033240 3 0.011
response to peptide hormone GO:0043434 278 0.011
behavior GO:0007610 205 0.011
positive regulation of protein modification process GO:0031401 142 0.011
monovalent inorganic cation transport GO:0015672 172 0.011
embryo development GO:0009790 49 0.011
ribonucleoside triphosphate catabolic process GO:0009203 122 0.011
positive regulation of cell differentiation GO:0045597 217 0.011
regulation of kinase activity GO:0043549 117 0.011
negative regulation of cell differentiation GO:0045596 99 0.011
establishment of tissue polarity GO:0007164 2 0.011
negative regulation of kidney development GO:0090185 2 0.011
negative regulation of metanephros development GO:0072217 2 0.011
cellular catabolic process GO:0044248 295 0.011
organonitrogen compound catabolic process GO:1901565 179 0.010
gastrulation GO:0007369 2 0.010
regulation of canonical wnt signaling pathway GO:0060828 4 0.010
positive regulation of transport GO:0051050 245 0.010
protein dna complex disassembly GO:0032986 1 0.010
reproductive process GO:0022414 372 0.010
metal ion homeostasis GO:0055065 186 0.010
regulation of cellular ketone metabolic process GO:0010565 27 0.010
nucleotide catabolic process GO:0009166 139 0.010
blood circulation GO:0008015 183 0.010
neurological system process GO:0050877 219 0.010
purine ribonucleotide metabolic process GO:0009150 227 0.010
regulation of protein import into nucleus GO:0042306 24 0.010
ribonucleoside monophosphate metabolic process GO:0009161 88 0.010
regulation of peptide transport GO:0090087 87 0.010
positive regulation of neurogenesis GO:0050769 165 0.010

Eif4g1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.020
nervous system disease DOID:863 0 0.020
muscular disease DOID:0080000 0 0.015
musculoskeletal system disease DOID:17 0 0.015
muscle tissue disease DOID:66 0 0.015
myopathy DOID:423 0 0.011
central nervous system disease DOID:331 0 0.011
disease of metabolism DOID:0014667 0 0.011