Rattus norvegicus

0 known processes

Cox4i2

cytochrome c oxidase subunit IV isoform 2

(Aliases: Cox4b,CoxIV-2)

Cox4i2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
tissue development GO:0009888 252 0.345
response to peptide hormone GO:0043434 278 0.266
response to inorganic substance GO:0010035 377 0.261
response to carbohydrate GO:0009743 183 0.208
regulation of heart contraction GO:0008016 48 0.202
programmed cell death GO:0012501 392 0.193
apoptotic process GO:0006915 381 0.191
response to hypoxia GO:0001666 231 0.171
muscle system process GO:0003012 115 0.141
cellular component assembly GO:0022607 360 0.138
cellular response to oxygen containing compound GO:1901701 386 0.135
regulation of cell differentiation GO:0045595 320 0.130
response to oxygen levels GO:0070482 265 0.128
response to nutrient GO:0007584 248 0.128
Rat
cellular component biogenesis GO:0044085 368 0.123
heart morphogenesis GO:0003007 3 0.122
homeostatic process GO:0042592 331 0.122
monovalent inorganic cation transport GO:0015672 172 0.121
response to metal ion GO:0010038 253 0.111
response to extracellular stimulus GO:0009991 380 0.107
Rat
defecation GO:0030421 1 0.104
regulation of blood pressure GO:0008217 83 0.104
heart contraction GO:0060047 57 0.103
cation transport GO:0006812 382 0.100
regulation of cell proliferation GO:0042127 359 0.097
macromolecular complex assembly GO:0065003 273 0.095
organ morphogenesis GO:0009887 75 0.089
gland development GO:0048732 155 0.084
rhythmic process GO:0048511 156 0.083
macromolecular complex subunit organization GO:0043933 339 0.081
response to decreased oxygen levels GO:0036293 237 0.081
blood circulation GO:0008015 183 0.081
organelle organization GO:0006996 266 0.080
protein complex assembly GO:0006461 263 0.080
response to transition metal nanoparticle GO:1990267 122 0.080
response to peptide GO:1901652 292 0.076
regulation of programmed cell death GO:0043067 341 0.075
cellular response to stress GO:0033554 269 0.075
response to estrogen GO:0043627 232 0.075
regulation of cellular component organization GO:0051128 368 0.075
cardiovascular system development GO:0072358 134 0.072
positive regulation of multicellular organismal process GO:0051240 387 0.071
central nervous system development GO:0007417 311 0.070
response to ketone GO:1901654 182 0.070
epithelium development GO:0060429 96 0.070
cellular response to nitrogen compound GO:1901699 210 0.069
reproductive process GO:0022414 372 0.066
cytoskeleton organization GO:0007010 111 0.065
response to cocaine GO:0042220 39 0.065
cellular response to lipid GO:0071396 201 0.063
response to alkaloid GO:0043279 132 0.061
regulation of system process GO:0044057 208 0.061
positive regulation of transport GO:0051050 245 0.061
transmembrane transport GO:0055085 412 0.061
response to wounding GO:0009611 254 0.059
response to glucocorticoid GO:0051384 223 0.058
protein complex biogenesis GO:0070271 263 0.058
response to nutrient levels GO:0031667 370 0.057
Rat
regulation of blood circulation GO:1903522 110 0.056
response to acid chemical GO:0001101 222 0.053
response to monosaccharide GO:0034284 159 0.053
cellular response to peptide GO:1901653 133 0.052
response to corticosteroid GO:0031960 235 0.052
metal ion transport GO:0030001 289 0.052
response to purine containing compound GO:0014074 126 0.051
regulation of cell development GO:0060284 263 0.051
protein complex subunit organization GO:0071822 302 0.051
multicellular organism reproduction GO:0032504 233 0.049
response to cytokine GO:0034097 215 0.049
negative regulation of cell proliferation GO:0008285 119 0.048
negative regulation of cell death GO:0060548 229 0.047
response to hexose GO:0009746 144 0.047
reproduction GO:0000003 245 0.047
cellular response to acid chemical GO:0071229 75 0.045
negative regulation of multicellular organismal process GO:0051241 203 0.045
protein heterooligomerization GO:0051291 89 0.045
response to other organism GO:0051707 220 0.045
positive regulation of cell differentiation GO:0045597 217 0.044
muscle tissue development GO:0060537 58 0.044
positive regulation of biosynthetic process GO:0009891 319 0.042
head development GO:0060322 247 0.042
negative regulation of apoptotic process GO:0043066 181 0.041
neurological system process GO:0050877 219 0.041
multi organism reproductive process GO:0044703 262 0.040
rna metabolic process GO:0016070 406 0.040
regulation of cellular component movement GO:0051270 150 0.040
positive regulation of cellular component organization GO:0051130 200 0.039
response to electrical stimulus GO:0051602 56 0.039
reproductive system development GO:0061458 128 0.039
positive regulation of developmental process GO:0051094 283 0.039
negative regulation of programmed cell death GO:0043069 183 0.038
response to retinoic acid GO:0032526 63 0.038
regulation of blood vessel size GO:0050880 89 0.038
brain development GO:0007420 247 0.037
circulatory system process GO:0003013 183 0.036
negative regulation of macromolecule metabolic process GO:0010605 260 0.035
regulation of apoptotic process GO:0042981 335 0.035
positive regulation of signaling GO:0023056 270 0.035
regulation of stem cell differentiation GO:2000736 2 0.034
calcium ion homeostasis GO:0055074 162 0.034
developmental process involved in reproduction GO:0003006 159 0.033
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.033
negative regulation of protein metabolic process GO:0051248 114 0.033
ion transmembrane transport GO:0034220 365 0.033
muscle structure development GO:0061061 87 0.032
catabolic process GO:0009056 351 0.032
positive regulation of gene expression GO:0010628 244 0.032
multicellular organismal reproductive process GO:0048609 233 0.032
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.032
potassium ion transport GO:0006813 97 0.032
organic substance catabolic process GO:1901575 316 0.031
protein oligomerization GO:0051259 191 0.031
regulation of molecular function GO:0065009 398 0.031
intracellular transport GO:0046907 185 0.030
cellular homeostasis GO:0019725 252 0.030
female pregnancy GO:0007565 122 0.029
multi multicellular organism process GO:0044706 138 0.028
positive regulation of peptide secretion GO:0002793 52 0.028
cellular component movement GO:0006928 248 0.028
glial cell differentiation GO:0010001 65 0.028
regulation of ion homeostasis GO:2000021 63 0.028
anterior posterior pattern specification GO:0009952 1 0.027
immune system process GO:0002376 204 0.027
response to calcium ion GO:0051592 59 0.027
positive regulation of peptide hormone secretion GO:0090277 50 0.027
regulation of organ formation GO:0003156 2 0.027
negative regulation of signaling GO:0023057 157 0.027
cardiac chamber development GO:0003205 1 0.026
action potential GO:0001508 54 0.026
cellular chemical homeostasis GO:0055082 247 0.026
cell cycle GO:0007049 101 0.026
positive regulation of transcription dna templated GO:0045893 197 0.026
response to ethanol GO:0045471 162 0.026
chemical homeostasis GO:0048878 292 0.025
response to vitamin GO:0033273 131 0.025
carbohydrate homeostasis GO:0033500 75 0.025
aging GO:0007568 241 0.025
single organism carbohydrate metabolic process GO:0044723 118 0.025
heart development GO:0007507 72 0.025
potassium ion transmembrane transport GO:0071805 71 0.025
negative regulation of metabolic process GO:0009892 331 0.025
positive regulation of blood circulation GO:1903524 65 0.025
blood vessel morphogenesis GO:0048514 58 0.025
circulatory system development GO:0072359 134 0.025
proteolysis GO:0006508 175 0.025
regulation of secretion by cell GO:1903530 208 0.024
transcription dna templated GO:0006351 377 0.024
positive regulation of secretion GO:0051047 140 0.024
regulation of ion transport GO:0043269 245 0.024
purine containing compound metabolic process GO:0072521 253 0.024
single organism biosynthetic process GO:0044711 342 0.024
excretion GO:0007588 24 0.024
regulation of rna biosynthetic process GO:2001141 381 0.024
rna biosynthetic process GO:0032774 380 0.023
positive regulation of secretion by cell GO:1903532 128 0.023
endocrine system development GO:0035270 30 0.023
regulation of rna metabolic process GO:0051252 391 0.023
carbohydrate metabolic process GO:0005975 130 0.022
positive regulation of rna metabolic process GO:0051254 203 0.022
muscle contraction GO:0006936 88 0.022
epithelial cell differentiation GO:0030855 71 0.022
negative regulation of cellular metabolic process GO:0031324 281 0.022
regulation of peptide secretion GO:0002791 82 0.022
single organism intracellular transport GO:1902582 166 0.021
regeneration GO:0031099 163 0.021
development of primary sexual characteristics GO:0045137 107 0.021
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.021
renal system development GO:0072001 67 0.021
positive regulation of molecular function GO:0044093 230 0.021
vasoconstriction GO:0042310 54 0.021
positive regulation of cell proliferation GO:0008284 249 0.021
cellular response to organic cyclic compound GO:0071407 202 0.021
response to nicotine GO:0035094 51 0.021
positive regulation of cell death GO:0010942 184 0.021
positive regulation of nucleic acid templated transcription GO:1903508 197 0.021
reproductive structure development GO:0048608 128 0.020
carboxylic acid transport GO:0046942 115 0.020
heart process GO:0003015 57 0.020
sexual reproduction GO:0019953 148 0.020
cellular response to hormone stimulus GO:0032870 247 0.020
positive regulation of rna biosynthetic process GO:1902680 197 0.020
actin filament based process GO:0030029 86 0.020
cell adhesion GO:0007155 110 0.020
regulation of cellular amine metabolic process GO:0033238 8 0.020
positive regulation of programmed cell death GO:0043068 157 0.020
response to camp GO:0051591 91 0.020
secretion by cell GO:0032940 248 0.019
regulation of membrane potential GO:0042391 110 0.019
inorganic ion transmembrane transport GO:0098660 229 0.019
cellular catabolic process GO:0044248 295 0.019
oxoacid metabolic process GO:0043436 290 0.019
regulation of epithelial cell proliferation GO:0050678 49 0.019
cell cell junction organization GO:0045216 20 0.019
single organism behavior GO:0044708 130 0.019
anatomical structure formation involved in morphogenesis GO:0048646 83 0.019
nucleic acid templated transcription GO:0097659 379 0.019
single organism organelle organization GO:1902589 180 0.019
response to organophosphorus GO:0046683 102 0.019
single organism reproductive process GO:0044702 297 0.019
regulation of fat cell differentiation GO:0045598 3 0.018
peptide secretion GO:0002790 86 0.018
peptide hormone secretion GO:0030072 84 0.018
response to glucose GO:0009749 136 0.018
regulation of cellular component biogenesis GO:0044087 86 0.018
carboxylic acid biosynthetic process GO:0046394 83 0.018
regulation of growth GO:0040008 105 0.018
positive regulation of cellular biosynthetic process GO:0031328 295 0.018
regulation of endothelial cell differentiation GO:0045601 4 0.018
regulation of metal ion transport GO:0010959 118 0.018
cellular response to peptide hormone stimulus GO:0071375 120 0.018
vascular process in circulatory system GO:0003018 96 0.018
regulation of immune system process GO:0002682 123 0.017
negative regulation of cell communication GO:0010648 158 0.017
cellular response to retinoic acid GO:0071300 27 0.017
biological adhesion GO:0022610 110 0.017
regulation of neurogenesis GO:0050767 247 0.017
regulation of secretion GO:0051046 224 0.017
sensory organ development GO:0007423 74 0.016
regulation of cell migration GO:0030334 128 0.016
blood vessel development GO:0001568 69 0.016
cell type specific apoptotic process GO:0097285 134 0.016
cell projection organization GO:0030030 302 0.016
cellular response to hexose stimulus GO:0071331 65 0.016
response to fatty acid GO:0070542 65 0.016
regulation of transcription dna templated GO:0006355 374 0.016
positive regulation of lipid kinase activity GO:0090218 2 0.016
response to zinc ion GO:0010043 39 0.016
regulation of response to external stimulus GO:0032101 106 0.016
organic acid metabolic process GO:0006082 292 0.016
negative regulation of follicle stimulating hormone secretion GO:0046882 3 0.016
response to oxidative stress GO:0006979 186 0.016
defense response GO:0006952 194 0.016
regulation of muscle system process GO:0090257 79 0.016
regulation of nucleic acid templated transcription GO:1903506 380 0.016
cardiac ventricle development GO:0003231 1 0.016
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.015
sequestering of metal ion GO:0051238 9 0.015
epithelial cell proliferation GO:0050673 54 0.015
regulation of anatomical structure size GO:0090066 135 0.015
positive regulation of heart contraction GO:0045823 15 0.015
cellular ion homeostasis GO:0006873 184 0.015
response to insulin GO:0032868 133 0.015
cellular potassium ion transport GO:0071804 72 0.015
organic hydroxy compound metabolic process GO:1901615 115 0.015
gliogenesis GO:0042063 93 0.015
striated muscle contraction GO:0006941 44 0.015
response to biotic stimulus GO:0009607 226 0.015
regulation of multicellular organismal development GO:2000026 376 0.015
positive regulation of dopamine secretion GO:0033603 8 0.015
response to external biotic stimulus GO:0043207 221 0.015
glucose homeostasis GO:0042593 75 0.014
smooth muscle cell migration GO:0014909 36 0.014
regulation of tube size GO:0035150 89 0.014
negative regulation of response to stimulus GO:0048585 155 0.014
response to ammonium ion GO:0060359 71 0.014
amide transport GO:0042886 105 0.014
regulation of phagocytosis engulfment GO:0060099 4 0.014
cellular response to monosaccharide stimulus GO:0071326 67 0.014
positive regulation of cellular amine metabolic process GO:0033240 3 0.014
cation homeostasis GO:0055080 195 0.014
positive regulation of cell development GO:0010720 176 0.014
regulation of catabolic process GO:0009894 113 0.014
actin cytoskeleton organization GO:0030036 73 0.014
regulation of neuron differentiation GO:0045664 208 0.014
circadian rhythm GO:0007623 88 0.014
regulation of response to stress GO:0080134 126 0.013
carbohydrate derivative biosynthetic process GO:1901137 124 0.013
regulation of defense response GO:0031347 68 0.013
metal ion homeostasis GO:0055065 186 0.013
regulation of cellular localization GO:0060341 263 0.013
gastric motility GO:0035482 3 0.013
cellular response to abiotic stimulus GO:0071214 85 0.013
vesicle mediated transport GO:0016192 181 0.013
spindle organization GO:0007051 2 0.013
oxidation reduction process GO:0055114 304 0.013
regulation of ion transmembrane transport GO:0034765 121 0.013
secretion GO:0046903 307 0.013
cellular amine metabolic process GO:0044106 38 0.013
gamete generation GO:0007276 124 0.013
regulation of anatomical structure morphogenesis GO:0022603 141 0.013
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.013
cellular metal ion homeostasis GO:0006875 172 0.013
regulation of homeostatic process GO:0032844 101 0.013
cell junction organization GO:0034330 21 0.013
sensory perception GO:0007600 101 0.012
negative regulation of g protein coupled receptor protein signaling pathway GO:0045744 15 0.012
regulation of cell adhesion GO:0030155 52 0.012
smooth muscle cell proliferation GO:0048659 77 0.012
hepaticobiliary system development GO:0061008 90 0.012
cellular divalent inorganic cation homeostasis GO:0072503 162 0.012
pro t cell differentiation GO:0002572 1 0.012
negative regulation of signal transduction GO:0009968 83 0.012
cellular response to carbohydrate stimulus GO:0071322 72 0.012
regulation of peptide transport GO:0090087 87 0.012
nucleotide metabolic process GO:0009117 279 0.012
ossification GO:0001503 70 0.012
cytoplasmic transport GO:0016482 115 0.012
behavior GO:0007610 205 0.012
regulation of smooth muscle cell migration GO:0014910 36 0.012
vasculature development GO:0001944 70 0.012
regulation of cell motility GO:2000145 131 0.012
positive regulation of hepatocyte differentiation GO:0070368 2 0.012
positive regulation of ion transport GO:0043270 94 0.012
cellular response to glucose stimulus GO:0071333 65 0.012
locomotor rhythm GO:0045475 1 0.012
regulation of catalytic activity GO:0050790 304 0.012
neuron differentiation GO:0030182 368 0.012
carbohydrate derivative metabolic process GO:1901135 346 0.012
positive regulation of cell motility GO:2000147 97 0.012
carboxylic acid metabolic process GO:0019752 289 0.012
anatomical structure morphogenesis GO:0009653 298 0.012
cellular lipid metabolic process GO:0044255 208 0.012
response to osmotic stress GO:0006970 42 0.011
divalent inorganic cation homeostasis GO:0072507 165 0.011
cellular amino acid metabolic process GO:0006520 107 0.011
skeletal system development GO:0001501 41 0.011
positive regulation of fibroblast proliferation GO:0048146 15 0.011
positive regulation of voltage gated calcium channel activity GO:1901387 1 0.011
male gonad development GO:0008584 59 0.011
amine metabolic process GO:0009308 38 0.011
synapse assembly GO:0007416 29 0.011
response to amino acid GO:0043200 75 0.011
negative regulation of gene expression GO:0010629 199 0.011
cellular response to external stimulus GO:0071496 118 0.011
locomotory exploration behavior GO:0035641 1 0.011
response to progesterone GO:0032570 48 0.011
urogenital system development GO:0001655 78 0.011
cyclic nucleotide metabolic process GO:0009187 80 0.011
regulation of signal transduction GO:0009966 318 0.011
cell morphogenesis GO:0000902 142 0.011
regulation of smooth muscle cell proliferation GO:0048660 75 0.011
regulation of protein metabolic process GO:0051246 289 0.011
cellular glucose homeostasis GO:0001678 66 0.011
neuron fate commitment GO:0048663 4 0.011
single organism catabolic process GO:0044712 283 0.011
male gamete generation GO:0048232 99 0.011
cellular calcium ion homeostasis GO:0006874 160 0.011
sodium ion transport GO:0006814 82 0.011
regulation of phosphorus metabolic process GO:0051174 349 0.011
positive regulation of apoptotic process GO:0043065 154 0.011
cellular response to inorganic substance GO:0071241 65 0.011
fibroblast proliferation GO:0048144 22 0.010
synaptic transmission GO:0007268 235 0.010
regulation of protein localization GO:0032880 81 0.010
development of primary male sexual characteristics GO:0046546 59 0.010
smooth muscle contraction GO:0006939 37 0.010
negative regulation of biosynthetic process GO:0009890 168 0.010
positive regulation of phosphate metabolic process GO:0045937 262 0.010
response to toxic substance GO:0009636 133 0.010
cardiac muscle tissue morphogenesis GO:0055008 1 0.010
regulation of metanephros development GO:0072215 4 0.010
protein localization GO:0008104 191 0.010
skeletal muscle cell differentiation GO:0035914 2 0.010

Cox4i2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.119
nervous system disease DOID:863 0 0.119
sensory system disease DOID:0050155 0 0.112
eye and adnexa disease DOID:1492 0 0.112
eye disease DOID:5614 0 0.112
retinal disease DOID:5679 0 0.023
central nervous system disease DOID:331 0 0.015