Rattus norvegicus

94 known processes

Rab8a

RAB8A, member RAS oncogene family

(Aliases: Mel,MGC124948,Rab8)

Rab8a biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
organelle organization GO:0006996 266 0.123
Human Yeast Zebrafish Rat
macromolecule localization GO:0033036 252 0.086
regulation of cellular component organization GO:0051128 368 0.073
Rat
negative regulation of cellular metabolic process GO:0031324 281 0.068
intracellular signal transduction GO:0035556 314 0.063
Rat
positive regulation of catalytic activity GO:0043085 184 0.059
nucleoside phosphate metabolic process GO:0006753 283 0.052
Human Yeast
carbohydrate derivative metabolic process GO:1901135 346 0.052
Human Yeast
organophosphate metabolic process GO:0019637 370 0.051
Human Yeast
cell projection organization GO:0030030 302 0.050
nucleoside metabolic process GO:0009116 179 0.049
Human Yeast
ribonucleoside metabolic process GO:0009119 174 0.046
Human Yeast
nucleoside phosphate catabolic process GO:1901292 140 0.045
Human Yeast
nucleobase containing small molecule metabolic process GO:0055086 316 0.044
Human Yeast
purine containing compound metabolic process GO:0072521 253 0.044
Human Yeast
reproduction GO:0000003 245 0.042
Yeast
nucleotide metabolic process GO:0009117 279 0.042
Human Yeast
organophosphate catabolic process GO:0046434 148 0.041
Human Yeast
regulation of plasma lipoprotein particle levels GO:0097006 3 0.041
macromolecular complex subunit organization GO:0043933 339 0.040
protein localization GO:0008104 191 0.040
response to peptide GO:1901652 292 0.039
transmembrane transport GO:0055085 412 0.038
response to peptide hormone GO:0043434 278 0.038
regulation of molecular function GO:0065009 398 0.036
homeostatic process GO:0042592 331 0.035
cellular component biogenesis GO:0044085 368 0.035
Human
single organism intracellular transport GO:1902582 166 0.035
Human Yeast
cellular response to oxygen containing compound GO:1901701 386 0.034
multicellular organismal reproductive process GO:0048609 233 0.034
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.033
purine ribonucleoside triphosphate metabolic process GO:0009205 140 0.033
Human Yeast
programmed cell death GO:0012501 392 0.033
protein complex subunit organization GO:0071822 302 0.032
positive regulation of transport GO:0051050 245 0.032
Rat
intracellular transport GO:0046907 185 0.032
Human Yeast
nitrogen compound transport GO:0071705 229 0.032
Rat
golgi vesicle transport GO:0048193 22 0.032
Human Yeast
catabolic process GO:0009056 351 0.032
Human Yeast
regulation of catalytic activity GO:0050790 304 0.031
positive regulation of molecular function GO:0044093 230 0.030
behavior GO:0007610 205 0.030
protein transport GO:0015031 132 0.030
cellular component morphogenesis GO:0032989 155 0.030
positive regulation of cell communication GO:0010647 271 0.029
Rat
negative regulation of metabolic process GO:0009892 331 0.029
purine nucleoside metabolic process GO:0042278 169 0.028
Human Yeast
regulation of multicellular organismal development GO:2000026 376 0.028
purine nucleotide metabolic process GO:0006163 229 0.028
Human Yeast
cellular response to stress GO:0033554 269 0.028
aromatic compound catabolic process GO:0019439 168 0.027
Human Yeast
nucleoside triphosphate catabolic process GO:0009143 123 0.027
Human Yeast
macromolecular complex assembly GO:0065003 273 0.027
response to extracellular stimulus GO:0009991 380 0.027
ribose phosphate metabolic process GO:0019693 235 0.027
Human Yeast
response to wounding GO:0009611 254 0.026
positive regulation of response to stimulus GO:0048584 285 0.026
rna metabolic process GO:0016070 406 0.026
cellular lipid metabolic process GO:0044255 208 0.025
single organism reproductive process GO:0044702 297 0.025
Yeast Rat
ribonucleoside triphosphate metabolic process GO:0009199 141 0.025
Human Yeast
neuron projection development GO:0031175 273 0.025
anion transport GO:0006820 178 0.025
lipid metabolic process GO:0006629 283 0.025
regulation of programmed cell death GO:0043067 341 0.025
neuron death GO:0070997 127 0.024
heterocycle catabolic process GO:0046700 167 0.024
Human Yeast
circulatory system process GO:0003013 183 0.024
organic anion transport GO:0015711 132 0.024
secretion GO:0046903 307 0.024
Human Yeast Rat
purine ribonucleotide metabolic process GO:0009150 227 0.024
Human Yeast
carbohydrate derivative biosynthetic process GO:1901137 124 0.024
cellular response to peptide hormone stimulus GO:0071375 120 0.024
positive regulation of intracellular signal transduction GO:1902533 138 0.023
ribonucleotide metabolic process GO:0009259 231 0.023
Human Yeast
protein complex biogenesis GO:0070271 263 0.023
nucleic acid templated transcription GO:0097659 379 0.023
regulation of vesicle mediated transport GO:0060627 81 0.022
anatomical structure morphogenesis GO:0009653 298 0.022
neurological system process GO:0050877 219 0.022
blood circulation GO:0008015 183 0.022
organophosphate biosynthetic process GO:0090407 143 0.022
cation transport GO:0006812 382 0.022
regulation of hormone levels GO:0010817 187 0.022
Rat
regulation of protein metabolic process GO:0051246 289 0.021
regulation of anatomical structure size GO:0090066 135 0.021
cellular chemical homeostasis GO:0055082 247 0.021
organic acid transport GO:0015849 116 0.021
response to inorganic substance GO:0010035 377 0.021
establishment of protein localization GO:0045184 141 0.021
regulation of intracellular signal transduction GO:1902531 218 0.021
apoptotic process GO:0006915 381 0.020
cellular catabolic process GO:0044248 295 0.020
Human Yeast
nucleobase containing compound catabolic process GO:0034655 152 0.020
Human Yeast
positive regulation of cellular biosynthetic process GO:0031328 295 0.020
cellular component assembly GO:0022607 360 0.020
Human
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.020
membrane organization GO:0061024 94 0.020
regulation of secretion GO:0051046 224 0.020
Rat
organic acid metabolic process GO:0006082 292 0.019
organic cyclic compound catabolic process GO:1901361 175 0.019
Human Yeast
neuron differentiation GO:0030182 368 0.019
organic substance catabolic process GO:1901575 316 0.019
Human Yeast
localization of cell GO:0051674 202 0.019
positive regulation of phosphate metabolic process GO:0045937 262 0.019
carboxylic acid metabolic process GO:0019752 289 0.019
carbohydrate metabolic process GO:0005975 130 0.019
head development GO:0060322 247 0.019
cell morphogenesis involved in differentiation GO:0000904 119 0.019
oxoacid metabolic process GO:0043436 290 0.019
neuron development GO:0048666 286 0.018
purine containing compound catabolic process GO:0072523 138 0.018
Human Yeast
positive regulation of biosynthetic process GO:0009891 319 0.018
cytoplasmic transport GO:0016482 115 0.018
Yeast
cell cycle GO:0007049 101 0.018
Yeast
lipid storage GO:0019915 1 0.018
atp metabolic process GO:0046034 72 0.018
anatomical structure formation involved in morphogenesis GO:0048646 83 0.018
Human Yeast
cellular ion homeostasis GO:0006873 184 0.018
response to metal ion GO:0010038 253 0.018
regulation of body fluid levels GO:0050878 90 0.018
cellular protein localization GO:0034613 122 0.017
wound healing GO:0042060 122 0.017
locomotion GO:0040011 237 0.017
transcription dna templated GO:0006351 377 0.017
single organism biosynthetic process GO:0044711 342 0.017
regulation of transcription dna templated GO:0006355 374 0.017
regulation of phosphate metabolic process GO:0019220 349 0.017
small gtpase mediated signal transduction GO:0007264 36 0.017
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.017
chemical homeostasis GO:0048878 292 0.017
cell projection morphogenesis GO:0048858 123 0.017
cellular homeostasis GO:0019725 252 0.016
regulation of cell proliferation GO:0042127 359 0.016
ion transmembrane transport GO:0034220 365 0.016
positive regulation of signaling GO:0023056 270 0.016
Rat
cellular response to endogenous stimulus GO:0071495 377 0.016
regulation of nucleic acid templated transcription GO:1903506 380 0.016
protein oligomerization GO:0051259 191 0.016
positive regulation of cellular component organization GO:0051130 200 0.016
Rat
single organism carbohydrate metabolic process GO:0044723 118 0.016
cellular component movement GO:0006928 248 0.016
purine ribonucleoside metabolic process GO:0046128 168 0.016
Human Yeast
positive regulation of cell death GO:0010942 184 0.016
regulation of cellular localization GO:0060341 263 0.016
Rat
plasma lipoprotein particle clearance GO:0034381 3 0.016
purine nucleotide catabolic process GO:0006195 136 0.016
Human Yeast
response to ethanol GO:0045471 162 0.015
single organism behavior GO:0044708 130 0.015
single organism organelle organization GO:1902589 180 0.015
Human Yeast Zebrafish Rat
negative regulation of signaling GO:0023057 157 0.015
regulation of phosphorus metabolic process GO:0051174 349 0.015
actin cytoskeleton organization GO:0030036 73 0.015
Rat
circadian regulation of gene expression GO:0032922 3 0.015
vesicle mediated transport GO:0016192 181 0.015
Human Yeast
purine nucleoside catabolic process GO:0006152 124 0.015
Human Yeast
mapk cascade GO:0000165 140 0.015
regulation of cell differentiation GO:0045595 320 0.015
epithelium development GO:0060429 96 0.015
Rat
metal ion transport GO:0030001 289 0.015
regulation of signal transduction GO:0009966 318 0.015
positive regulation of protein metabolic process GO:0051247 178 0.014
negative regulation of neurogenesis GO:0050768 78 0.014
sensory organ development GO:0007423 74 0.014
regulation of apoptotic process GO:0042981 335 0.014
organelle inheritance GO:0048308 2 0.014
Yeast
positive regulation of phosphorus metabolic process GO:0010562 262 0.014
ribonucleoside monophosphate metabolic process GO:0009161 88 0.014
cellular response to abiotic stimulus GO:0071214 85 0.014
regulation of homeostatic process GO:0032844 101 0.014
nucleotide catabolic process GO:0009166 139 0.014
Human Yeast
lipid localization GO:0010876 62 0.014
intracellular protein transport GO:0006886 79 0.014
regulation of rna biosynthetic process GO:2001141 381 0.014
organonitrogen compound catabolic process GO:1901565 179 0.014
Human Yeast
glycosyl compound metabolic process GO:1901657 182 0.014
Human Yeast
cellular cation homeostasis GO:0030003 180 0.014
male gamete generation GO:0048232 99 0.014
positive regulation of cell proliferation GO:0008284 249 0.014
gamete generation GO:0007276 124 0.013
cellular response to nitrogen compound GO:1901699 210 0.013
negative regulation of cellular component organization GO:0051129 83 0.013
ribonucleoside triphosphate catabolic process GO:0009203 122 0.013
Human Yeast
ras protein signal transduction GO:0007265 29 0.013
cellular response to organonitrogen compound GO:0071417 197 0.013
dna metabolic process GO:0006259 96 0.013
camera type eye development GO:0043010 48 0.013
response to ketone GO:1901654 182 0.013
cellular response to hormone stimulus GO:0032870 247 0.013
secretion by cell GO:0032940 248 0.013
Human Yeast Rat
regulation of response to external stimulus GO:0032101 106 0.013
positive regulation of developmental process GO:0051094 283 0.013
regulation of nervous system development GO:0051960 264 0.013
ion homeostasis GO:0050801 212 0.013
negative regulation of protein metabolic process GO:0051248 114 0.013
nucleoside monophosphate catabolic process GO:0009125 56 0.013
spermatogenesis GO:0007283 99 0.013
sexual reproduction GO:0019953 148 0.013
Yeast
sensory perception GO:0007600 101 0.013
protein phosphorylation GO:0006468 345 0.013
cellular ketone metabolic process GO:0042180 51 0.013
response to carbohydrate GO:0009743 183 0.013
cell cell signaling GO:0007267 335 0.013
response to corticosteroid GO:0031960 235 0.012
regulation of endocytosis GO:0030100 42 0.012
actin filament based process GO:0030029 86 0.012
Rat
cellular amino acid metabolic process GO:0006520 107 0.012
vesicle fusion with golgi apparatus GO:0048280 4 0.012
synaptic transmission GO:0007268 235 0.012
dna replication GO:0006260 37 0.012
growth GO:0040007 165 0.012
heart morphogenesis GO:0003007 3 0.012
eye morphogenesis GO:0048592 4 0.012
response to hexose GO:0009746 144 0.012
cellular macromolecule localization GO:0070727 122 0.012
isoprenoid metabolic process GO:0006720 45 0.012
response to glucose GO:0009749 136 0.012
regulation of rna metabolic process GO:0051252 391 0.012
response to growth factor GO:0070848 189 0.012
purine ribonucleoside catabolic process GO:0046130 124 0.012
Human Yeast
cellular nitrogen compound catabolic process GO:0044270 163 0.012
Human Yeast
cell part morphogenesis GO:0032990 123 0.012
regulation of organelle organization GO:0033043 80 0.012
response to acid chemical GO:0001101 222 0.012
nucleoside monophosphate metabolic process GO:0009123 93 0.012
cellular amine metabolic process GO:0044106 38 0.012
circadian rhythm GO:0007623 88 0.012
amine metabolic process GO:0009308 38 0.012
cation transmembrane transport GO:0098655 263 0.012
cytokinetic process GO:0032506 1 0.012
Yeast
nucleoside triphosphate metabolic process GO:0009141 144 0.012
Human Yeast
regulation of cell development GO:0060284 263 0.012
proteolysis GO:0006508 175 0.011
inorganic ion transmembrane transport GO:0098660 229 0.011
salivary gland morphogenesis GO:0007435 1 0.011
cytoskeleton dependent cytokinesis GO:0061640 2 0.011
eye development GO:0001654 50 0.011
cation homeostasis GO:0055080 195 0.011
axis specification GO:0009798 4 0.011
regulation of cellular protein metabolic process GO:0032268 267 0.011
g protein coupled receptor signaling pathway GO:0007186 242 0.011
multi organism reproductive process GO:0044703 262 0.011
Yeast
central nervous system development GO:0007417 311 0.011
negative regulation of transport GO:0051051 136 0.011
response to insulin GO:0032868 133 0.011
cellular metal ion homeostasis GO:0006875 172 0.011
carboxylic acid transport GO:0046942 115 0.011
regulation of meiotic cell cycle GO:0051445 3 0.011
regulation of purine nucleotide metabolic process GO:1900542 115 0.011
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.011
brain development GO:0007420 247 0.011
intra golgi vesicle mediated transport GO:0006891 3 0.011
cell morphogenesis GO:0000902 142 0.011
vesicle organization GO:0016050 29 0.011
Human Yeast
negative regulation of macromolecule metabolic process GO:0010605 260 0.011
regulation of secretion by cell GO:1903530 208 0.011
Rat
negative regulation of gene expression GO:0010629 199 0.011
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.011
gtp catabolic process GO:0006184 71 0.011
Human Yeast
lipid transport GO:0006869 61 0.010
positive regulation of phosphorylation GO:0042327 177 0.010
neural crest cell migration GO:0001755 1 0.010
multicellular organism reproduction GO:0032504 233 0.010
b cell differentiation GO:0030183 2 0.010
negative regulation of cell cycle phase transition GO:1901988 4 0.010
protein complex assembly GO:0006461 263 0.010
signal release GO:0023061 145 0.010
Rat
purine nucleoside triphosphate catabolic process GO:0009146 122 0.010
Human Yeast
reproductive process GO:0022414 372 0.010
Yeast Rat
response to nutrient levels GO:0031667 370 0.010
regulation of translation GO:0006417 27 0.010
regulation of nucleotide metabolic process GO:0006140 117 0.010
negative regulation of multicellular organismal process GO:0051241 203 0.010
rna localization GO:0006403 4 0.010
purine ribonucleotide catabolic process GO:0009154 136 0.010
Human Yeast
oxidation reduction process GO:0055114 304 0.010

Rab8a disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.057
nervous system disease DOID:863 0 0.057
sensory system disease DOID:0050155 0 0.032
musculoskeletal system disease DOID:17 0 0.014
central nervous system disease DOID:331 0 0.012