Rattus norvegicus

0 known processes

Fam126b

family with sequence similarity 126, member B

(Aliases: MGC116143,RGD1309752)

Fam126b biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
regulation of nucleic acid templated transcription GO:1903506 380 0.430
rna metabolic process GO:0016070 406 0.340
locomotion GO:0040011 237 0.255
regulation of rna metabolic process GO:0051252 391 0.251
rna biosynthetic process GO:0032774 380 0.224
nucleic acid templated transcription GO:0097659 379 0.198
protein phosphorylation GO:0006468 345 0.186
transcription from rna polymerase ii promoter GO:0006366 252 0.184
catabolic process GO:0009056 351 0.173
positive regulation of phosphate metabolic process GO:0045937 262 0.170
lipid biosynthetic process GO:0008610 128 0.170
transcription dna templated GO:0006351 377 0.133
regulation of rna biosynthetic process GO:2001141 381 0.133
regulation of phosphate metabolic process GO:0019220 349 0.128
positive regulation of rna metabolic process GO:0051254 203 0.126
negative regulation of nucleic acid templated transcription GO:1903507 117 0.119
central nervous system development GO:0007417 311 0.117
negative regulation of metabolic process GO:0009892 331 0.115
regulation of signal transduction GO:0009966 318 0.113
regulation of cellular protein metabolic process GO:0032268 267 0.113
negative regulation of cellular biosynthetic process GO:0031327 161 0.113
regulation of transcription dna templated GO:0006355 374 0.110
regulation of phosphorylation GO:0042325 248 0.109
organic acid metabolic process GO:0006082 292 0.106
positive regulation of phosphorylation GO:0042327 177 0.101
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.092
carboxylic acid metabolic process GO:0019752 289 0.092
negative regulation of biosynthetic process GO:0009890 168 0.087
monosaccharide metabolic process GO:0005996 61 0.083
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.081
positive regulation of phosphorus metabolic process GO:0010562 262 0.081
regulation of phosphorus metabolic process GO:0051174 349 0.074
oxoacid metabolic process GO:0043436 290 0.073
lipid metabolic process GO:0006629 283 0.073
carbohydrate derivative metabolic process GO:1901135 346 0.071
mapk cascade GO:0000165 140 0.069
positive regulation of signal transduction GO:0009967 175 0.067
regulation of mapk cascade GO:0043408 116 0.065
cellular component movement GO:0006928 248 0.065
regulation of cellular ketone metabolic process GO:0010565 27 0.064
regulation of protein metabolic process GO:0051246 289 0.064
protein complex assembly GO:0006461 263 0.064
protein oligomerization GO:0051259 191 0.062
chemical homeostasis GO:0048878 292 0.062
single organism reproductive process GO:0044702 297 0.059
negative regulation of cellular metabolic process GO:0031324 281 0.057
single organism biosynthetic process GO:0044711 342 0.057
positive regulation of secretion GO:0051047 140 0.057
positive regulation of transcription dna templated GO:0045893 197 0.057
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.057
circadian regulation of gene expression GO:0032922 3 0.056
protein complex biogenesis GO:0070271 263 0.056
macromolecular complex assembly GO:0065003 273 0.056
negative regulation of response to stimulus GO:0048585 155 0.055
head development GO:0060322 247 0.055
cellular hormone metabolic process GO:0034754 49 0.055
positive regulation of molecular function GO:0044093 230 0.055
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.055
brain development GO:0007420 247 0.055
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.054
positive regulation of rna biosynthetic process GO:1902680 197 0.053
homeostatic process GO:0042592 331 0.053
negative regulation of gene expression GO:0010629 199 0.053
cellular ketone metabolic process GO:0042180 51 0.050
regulation of molecular function GO:0065009 398 0.048
g protein coupled receptor signaling pathway GO:0007186 242 0.047
amine metabolic process GO:0009308 38 0.046
positive regulation of nucleic acid templated transcription GO:1903508 197 0.046
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.045
regulation of protein modification process GO:0031399 194 0.045
positive regulation of response to stimulus GO:0048584 285 0.044
positive regulation of protein modification process GO:0031401 142 0.044
behavior GO:0007610 205 0.044
positive regulation of gene expression GO:0010628 244 0.044
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.044
regulation of protein phosphorylation GO:0001932 183 0.044
protein autophosphorylation GO:0046777 66 0.043
negative regulation of cell communication GO:0010648 158 0.042
regulation of cellular amine metabolic process GO:0033238 8 0.041
positive regulation of biosynthetic process GO:0009891 319 0.041
organic substance catabolic process GO:1901575 316 0.041
negative regulation of signaling GO:0023057 157 0.040
macromolecule localization GO:0033036 252 0.040
carbohydrate catabolic process GO:0016052 40 0.040
regulation of catalytic activity GO:0050790 304 0.040
regulation of multicellular organismal development GO:2000026 376 0.039
signal transduction by phosphorylation GO:0023014 144 0.039
response to wounding GO:0009611 254 0.039
multicellular organism reproduction GO:0032504 233 0.039
secretion by cell GO:0032940 248 0.039
negative regulation of rna metabolic process GO:0051253 123 0.038
female sex differentiation GO:0046660 59 0.038
macromolecular complex subunit organization GO:0043933 339 0.037
wnt signaling pathway planar cell polarity pathway GO:0060071 2 0.037
stress activated protein kinase signaling cascade GO:0031098 37 0.037
regulation of catabolic process GO:0009894 113 0.037
neurological system process GO:0050877 219 0.037
development of primary sexual characteristics GO:0045137 107 0.036
reproductive process GO:0022414 372 0.036
reproductive structure development GO:0048608 128 0.035
negative regulation of macromolecule metabolic process GO:0010605 260 0.035
positive regulation of cellular biosynthetic process GO:0031328 295 0.035
regulation of lipid metabolic process GO:0019216 68 0.035
regulation of apoptotic process GO:0042981 335 0.034
cellular amine metabolic process GO:0044106 38 0.034
fructose 2 6 bisphosphate metabolic process GO:0006003 2 0.034
regeneration GO:0031099 163 0.034
response to inorganic substance GO:0010035 377 0.033
carbohydrate metabolic process GO:0005975 130 0.033
single organism carbohydrate metabolic process GO:0044723 118 0.033
cellular response to endogenous stimulus GO:0071495 377 0.032
aging GO:0007568 241 0.032
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.032
regulation of protein kinase activity GO:0045859 105 0.032
cellular response to stress GO:0033554 269 0.031
glutamate receptor signaling pathway GO:0007215 43 0.030
synaptic growth at neuromuscular junction GO:0051124 1 0.030
gonad development GO:0008406 104 0.030
positive regulation of cellular protein metabolic process GO:0032270 167 0.030
localization of cell GO:0051674 202 0.030
positive regulation of intracellular signal transduction GO:1902533 138 0.029
positive regulation of protein metabolic process GO:0051247 178 0.029
purine containing compound metabolic process GO:0072521 253 0.029
organophosphate metabolic process GO:0019637 370 0.029
response to corticosteroid GO:0031960 235 0.029
cell migration GO:0016477 197 0.029
cellular component biogenesis GO:0044085 368 0.029
reproduction GO:0000003 245 0.028
regulation of g protein coupled receptor protein signaling pathway GO:0008277 28 0.028
nucleobase containing small molecule metabolic process GO:0055086 316 0.028
nucleotide metabolic process GO:0009117 279 0.028
monocarboxylic acid metabolic process GO:0032787 152 0.028
negative regulation of signal transduction GO:0009968 83 0.028
multicellular organismal reproductive process GO:0048609 233 0.027
hexose metabolic process GO:0019318 58 0.027
jnk cascade GO:0007254 28 0.027
negative regulation of protein metabolic process GO:0051248 114 0.027
regulation of cellular amino acid metabolic process GO:0006521 2 0.027
neuron death GO:0070997 127 0.027
regulation of response to stress GO:0080134 126 0.027
cellular response to growth factor stimulus GO:0071363 162 0.026
response to glucocorticoid GO:0051384 223 0.026
single organism carbohydrate catabolic process GO:0044724 40 0.026
negative regulation of phosphorus metabolic process GO:0010563 80 0.026
regulation of system process GO:0044057 208 0.025
regulation of mrna splicing via spliceosome GO:0048024 3 0.025
oxidation reduction process GO:0055114 304 0.025
response to nutrient levels GO:0031667 370 0.025
intracellular receptor signaling pathway GO:0030522 35 0.025
c21 steroid hormone metabolic process GO:0008207 14 0.025
cell motility GO:0048870 202 0.025
alternative mrna splicing via spliceosome GO:0000380 4 0.024
maintenance of location GO:0051235 17 0.024
cellular macromolecule localization GO:0070727 122 0.024
ribose phosphate metabolic process GO:0019693 235 0.024
response to starvation GO:0042594 59 0.024
intracellular signal transduction GO:0035556 314 0.023
intracellular protein transport GO:0006886 79 0.023
positive regulation of developmental process GO:0051094 283 0.023
response to temperature stimulus GO:0009266 94 0.023
response to growth factor GO:0070848 189 0.023
cell type specific apoptotic process GO:0097285 134 0.023
hormone transport GO:0009914 121 0.023
hormone secretion GO:0046879 115 0.023
cation transport GO:0006812 382 0.023
cellular component assembly GO:0022607 360 0.022
cellular response to nitrogen compound GO:1901699 210 0.022
cellular protein localization GO:0034613 122 0.022
protein heterooligomerization GO:0051291 89 0.022
camera type eye development GO:0043010 48 0.022
stress activated mapk cascade GO:0051403 35 0.022
ribonucleotide metabolic process GO:0009259 231 0.022
regulation of jnk cascade GO:0046328 19 0.022
cellular amino acid metabolic process GO:0006520 107 0.022
regulation of behavior GO:0050795 61 0.022
positive regulation of cellular amine metabolic process GO:0033240 3 0.022
secretion GO:0046903 307 0.021
regulation of ion transport GO:0043269 245 0.021
inorganic cation transmembrane transport GO:0098662 202 0.021
divalent metal ion transport GO:0070838 132 0.021
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.021
vesicle mediated transport GO:0016192 181 0.021
single organism catabolic process GO:0044712 283 0.021
inorganic ion transmembrane transport GO:0098660 229 0.021
positive regulation of catalytic activity GO:0043085 184 0.021
regulation of cell development GO:0060284 263 0.021
cellular response to oxygen containing compound GO:1901701 386 0.020
sequestering of triglyceride GO:0030730 1 0.020
erk1 and erk2 cascade GO:0070371 48 0.020
organic cyclic compound catabolic process GO:1901361 175 0.020
cation homeostasis GO:0055080 195 0.020
hormone metabolic process GO:0042445 69 0.020
protein localization GO:0008104 191 0.020
cyclic nucleotide metabolic process GO:0009187 80 0.019
positive regulation of catabolic process GO:0009896 78 0.019
adult locomotory behavior GO:0008344 4 0.019
cellular ion homeostasis GO:0006873 184 0.019
small gtpase mediated signal transduction GO:0007264 36 0.019
signal release GO:0023061 145 0.019
positive regulation of cell communication GO:0010647 271 0.019
developmental process involved in reproduction GO:0003006 159 0.019
single organism organelle organization GO:1902589 180 0.019
regulation of hormone levels GO:0010817 187 0.019
cell cycle process GO:0022402 57 0.019
cellular divalent inorganic cation homeostasis GO:0072503 162 0.018
pyruvate metabolic process GO:0006090 27 0.018
peptidyl amino acid modification GO:0018193 126 0.018
programmed cell death GO:0012501 392 0.018
cellular homeostasis GO:0019725 252 0.018
positive regulation of mapk cascade GO:0043410 92 0.018
protein complex subunit organization GO:0071822 302 0.017
response to metal ion GO:0010038 253 0.017
response to peptide GO:1901652 292 0.017
positive regulation of signaling GO:0023056 270 0.017
cellular carbohydrate metabolic process GO:0044262 72 0.017
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.017
organ regeneration GO:0031100 101 0.017
regulation of locomotion GO:0040012 148 0.017
multi organism reproductive process GO:0044703 262 0.017
positive regulation of kinase activity GO:0033674 77 0.017
negative regulation of transport GO:0051051 136 0.017
protein transport GO:0015031 132 0.017
steroid biosynthetic process GO:0006694 48 0.016
response to peptide hormone GO:0043434 278 0.016
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.016
single organism cellular localization GO:1902580 102 0.016
regulation of transferase activity GO:0051338 123 0.016
negative regulation of neuron death GO:1901215 69 0.016
positive regulation of protein phosphorylation GO:0001934 135 0.016
response to decreased oxygen levels GO:0036293 237 0.016
regulation of protein serine threonine kinase activity GO:0071900 64 0.016
retinal metabolic process GO:0042574 3 0.016
negative regulation of apoptotic process GO:0043066 181 0.016
organelle organization GO:0006996 266 0.015
cofactor metabolic process GO:0051186 95 0.015
regulation of cellular catabolic process GO:0031329 101 0.015
development of primary female sexual characteristics GO:0046545 56 0.015
nucleobase containing compound catabolic process GO:0034655 152 0.015
response to ketone GO:1901654 182 0.015
positive regulation of protein serine threonine kinase activity GO:0071902 52 0.015
response to cytokine GO:0034097 215 0.015
calcium ion transport GO:0006816 131 0.015
intracellular transport GO:0046907 185 0.015
alcohol metabolic process GO:0006066 77 0.015
negative regulation of phosphate metabolic process GO:0045936 80 0.015
wound healing GO:0042060 122 0.015
response to estrogen GO:0043627 232 0.015
negative regulation of cellular protein metabolic process GO:0032269 106 0.015
apoptotic process GO:0006915 381 0.015
reactive nitrogen species metabolic process GO:2001057 1 0.015
cellular catabolic process GO:0044248 295 0.014
dephosphorylation GO:0016311 98 0.014
establishment of protein localization GO:0045184 141 0.014
single organism intracellular transport GO:1902582 166 0.014
cytokine production GO:0001816 61 0.014
positive regulation of cell proliferation GO:0008284 249 0.014
nucleoside phosphate metabolic process GO:0006753 283 0.014
organophosphate biosynthetic process GO:0090407 143 0.014
positive regulation of multicellular organismal process GO:0051240 387 0.014
negative regulation of programmed cell death GO:0043069 183 0.014
mitotic cell cycle process GO:1903047 35 0.014
regulation of intracellular signal transduction GO:1902531 218 0.014
regulation of cellular response to stress GO:0080135 49 0.014
activation of protein kinase b activity GO:0032148 3 0.014
organic hydroxy compound metabolic process GO:1901615 115 0.014
sex differentiation GO:0007548 113 0.014
regulation of neuron apoptotic process GO:0043523 83 0.014
regulation of stress activated mapk cascade GO:0032872 23 0.014
lipid storage GO:0019915 1 0.013
positive regulation of transferase activity GO:0051347 81 0.013
sexual reproduction GO:0019953 148 0.013
developmental growth GO:0048589 100 0.013
cellular chemical homeostasis GO:0055082 247 0.013
regulation of circadian rhythm GO:0042752 27 0.013
response to glucose GO:0009749 136 0.013
negative regulation of g protein coupled receptor protein signaling pathway GO:0045744 15 0.013
regulation of carbohydrate metabolic process GO:0006109 41 0.013
calcium ion transmembrane transport GO:0070588 70 0.013
carbohydrate homeostasis GO:0033500 75 0.013
angiogenesis GO:0001525 53 0.013
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 27 0.013
regulation of cellular localization GO:0060341 263 0.013
response to insulin GO:0032868 133 0.013
metal ion transport GO:0030001 289 0.013
sensory perception GO:0007600 101 0.013
regulation of reactive oxygen species biosynthetic process GO:1903426 5 0.012
negative regulation of rna splicing GO:0033119 3 0.012
cellular cation homeostasis GO:0030003 180 0.012
regulation of establishment of protein localization GO:0070201 69 0.012
protein tetramerization GO:0051262 38 0.012
glucose homeostasis GO:0042593 75 0.012
cellular lipid metabolic process GO:0044255 208 0.012
regulation of kinase activity GO:0043549 117 0.012
response to oxidative stress GO:0006979 186 0.012
purine nucleotide metabolic process GO:0006163 229 0.012
regulation of developmental growth GO:0048638 45 0.012
response to extracellular stimulus GO:0009991 380 0.012
negative adaptation of signaling pathway GO:0022401 10 0.012
single organism behavior GO:0044708 130 0.012
divalent inorganic cation homeostasis GO:0072507 165 0.012
neural crest cell development GO:0014032 2 0.012
neuromuscular process GO:0050905 2 0.012
cellular nitrogen compound catabolic process GO:0044270 163 0.012
heterocycle catabolic process GO:0046700 167 0.012
glycosyl compound metabolic process GO:1901657 182 0.012
nitrogen compound transport GO:0071705 229 0.012
non canonical wnt signaling pathway GO:0035567 3 0.012
macromolecule catabolic process GO:0009057 58 0.012
sensory perception of light stimulus GO:0050953 3 0.011
response to biotic stimulus GO:0009607 226 0.011
fatty acid oxidation GO:0019395 29 0.011
negative regulation of stress activated protein kinase signaling cascade GO:0070303 4 0.011
organic anion transport GO:0015711 132 0.011
negative regulation of rna biosynthetic process GO:1902679 118 0.011
organ growth GO:0035265 24 0.011
ribonucleotide catabolic process GO:0009261 136 0.011
response to reactive oxygen species GO:0000302 120 0.011
purine containing compound biosynthetic process GO:0072522 85 0.011
nucleoside phosphate catabolic process GO:1901292 140 0.011
neuron differentiation GO:0030182 368 0.011
positive regulation of secretion by cell GO:1903532 128 0.011
cell adhesion GO:0007155 110 0.011
mitotic spindle organization GO:0007052 2 0.011
anion transport GO:0006820 178 0.011
cyclic purine nucleotide metabolic process GO:0052652 62 0.011
neuron development GO:0048666 286 0.011
positive regulation of cell differentiation GO:0045597 217 0.011
regulation of anatomical structure morphogenesis GO:0022603 141 0.011
anatomical structure morphogenesis GO:0009653 298 0.011
positive regulation of cellular catabolic process GO:0031331 71 0.010
regulation of embryonic development GO:0045995 2 0.010
cellular response to metal ion GO:0071248 55 0.010
nucleoside metabolic process GO:0009116 179 0.010
ras protein signal transduction GO:0007265 29 0.010
neuron apoptotic process GO:0051402 88 0.010
steroid metabolic process GO:0008202 73 0.010
cellular macromolecular complex assembly GO:0034622 58 0.010
sequestering of metal ion GO:0051238 9 0.010
negative regulation of phosphorylation GO:0042326 57 0.010
isoprenoid metabolic process GO:0006720 45 0.010
c21 steroid hormone biosynthetic process GO:0006700 10 0.010
response to hydrogen peroxide GO:0042542 89 0.010
purine ribonucleotide metabolic process GO:0009150 227 0.010
cellular response to nutrient levels GO:0031669 60 0.010
regulation of cell migration GO:0030334 128 0.010
phototransduction visible light GO:0007603 2 0.010
exploration behavior GO:0035640 1 0.010
response to alkaloid GO:0043279 132 0.010
response to hypoxia GO:0001666 231 0.010
axis specification GO:0009798 4 0.010
epiboly involved in wound healing GO:0090505 2 0.010
negative regulation of catalytic activity GO:0043086 103 0.010
aromatic compound catabolic process GO:0019439 168 0.010
negative regulation of neuron apoptotic process GO:0043524 45 0.010
sequestering of calcium ion GO:0051208 8 0.010

Fam126b disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.071
nervous system disease DOID:863 0 0.071
central nervous system disease DOID:331 0 0.030
sensory system disease DOID:0050155 0 0.014
eye and adnexa disease DOID:1492 0 0.014
eye disease DOID:5614 0 0.014
disease of metabolism DOID:0014667 0 0.014
substance dependence DOID:9973 0 0.012
substance related disorder DOID:303 0 0.012
disease of mental health DOID:150 0 0.012
brain disease DOID:936 0 0.011