Rattus norvegicus

0 known processes

Kctd8

potassium channel tetramerisation domain containing 8

Kctd8 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
rna metabolic process GO:0016070 406 0.055
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.047
transcription dna templated GO:0006351 377 0.046
nucleic acid templated transcription GO:0097659 379 0.045
regulation of cell proliferation GO:0042127 359 0.043
regulation of transcription dna templated GO:0006355 374 0.042
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.042
cellular response to oxygen containing compound GO:1901701 386 0.041
regulation of nucleic acid templated transcription GO:1903506 380 0.041
regulation of multicellular organismal development GO:2000026 376 0.040
regulation of rna metabolic process GO:0051252 391 0.038
intracellular signal transduction GO:0035556 314 0.038
rna biosynthetic process GO:0032774 380 0.037
regulation of molecular function GO:0065009 398 0.036
oxoacid metabolic process GO:0043436 290 0.036
organic acid metabolic process GO:0006082 292 0.035
cellular response to endogenous stimulus GO:0071495 377 0.035
response to inorganic substance GO:0010035 377 0.034
reproductive process GO:0022414 372 0.033
Fly
nucleobase containing small molecule metabolic process GO:0055086 316 0.033
single organism reproductive process GO:0044702 297 0.033
chemical homeostasis GO:0048878 292 0.033
cellular component biogenesis GO:0044085 368 0.033
regulation of rna biosynthetic process GO:2001141 381 0.032
organophosphate metabolic process GO:0019637 370 0.032
regulation of phosphorus metabolic process GO:0051174 349 0.032
anatomical structure morphogenesis GO:0009653 298 0.032
carboxylic acid metabolic process GO:0019752 289 0.031
regulation of cell differentiation GO:0045595 320 0.031
positive regulation of biosynthetic process GO:0009891 319 0.030
multi organism reproductive process GO:0044703 262 0.030
Fly
homeostatic process GO:0042592 331 0.030
regulation of catalytic activity GO:0050790 304 0.029
response to nutrient levels GO:0031667 370 0.029
regulation of phosphate metabolic process GO:0019220 349 0.029
carbohydrate derivative metabolic process GO:1901135 346 0.029
cellular component assembly GO:0022607 360 0.029
regulation of programmed cell death GO:0043067 341 0.029
positive regulation of developmental process GO:0051094 283 0.029
transmembrane transport GO:0055085 412 0.029
amine metabolic process GO:0009308 38 0.029
cation transport GO:0006812 382 0.028
neuron differentiation GO:0030182 368 0.027
cellular amine metabolic process GO:0044106 38 0.027
positive regulation of phosphate metabolic process GO:0045937 262 0.027
transcription from rna polymerase ii promoter GO:0006366 252 0.027
cellular amino acid metabolic process GO:0006520 107 0.027
g protein coupled receptor signaling pathway GO:0007186 242 0.026
Mouse
organic substance catabolic process GO:1901575 316 0.026
nucleoside phosphate metabolic process GO:0006753 283 0.026
protein phosphorylation GO:0006468 345 0.026
reproduction GO:0000003 245 0.026
Fly
neuron projection development GO:0031175 273 0.026
positive regulation of cell proliferation GO:0008284 249 0.026
secretion GO:0046903 307 0.026
ion transmembrane transport GO:0034220 365 0.025
negative regulation of metabolic process GO:0009892 331 0.025
purine containing compound metabolic process GO:0072521 253 0.025
positive regulation of gene expression GO:0010628 244 0.025
regulation of cellular amine metabolic process GO:0033238 8 0.025
negative regulation of macromolecule metabolic process GO:0010605 260 0.025
positive regulation of multicellular organismal process GO:0051240 387 0.025
positive regulation of cellular biosynthetic process GO:0031328 295 0.025
cellular ketone metabolic process GO:0042180 51 0.025
cell cell signaling GO:0007267 335 0.025
nucleotide metabolic process GO:0009117 279 0.025
purine ribonucleotide metabolic process GO:0009150 227 0.025
catabolic process GO:0009056 351 0.025
regulation of apoptotic process GO:0042981 335 0.025
macromolecular complex subunit organization GO:0043933 339 0.025
regulation of cellular ketone metabolic process GO:0010565 27 0.025
regulation of cellular amino acid metabolic process GO:0006521 2 0.025
central nervous system development GO:0007417 311 0.024
single organism biosynthetic process GO:0044711 342 0.024
regulation of nervous system development GO:0051960 264 0.024
regulation of cell development GO:0060284 263 0.024
response to estrogen GO:0043627 232 0.024
regulation of cellular component organization GO:0051128 368 0.024
regulation of intracellular signal transduction GO:1902531 218 0.024
regulation of system process GO:0044057 208 0.024
positive regulation of response to stimulus GO:0048584 285 0.024
brain development GO:0007420 247 0.024
circulatory system process GO:0003013 183 0.024
response to oxygen levels GO:0070482 265 0.023
negative regulation of programmed cell death GO:0043069 183 0.023
negative regulation of cellular metabolic process GO:0031324 281 0.023
ribose phosphate metabolic process GO:0019693 235 0.023
ribonucleotide metabolic process GO:0009259 231 0.023
cellular chemical homeostasis GO:0055082 247 0.023
positive regulation of phosphorus metabolic process GO:0010562 262 0.023
response to peptide GO:1901652 292 0.023
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.023
apoptotic process GO:0006915 381 0.023
regulation of signal transduction GO:0009966 318 0.023
Mouse
positive regulation of molecular function GO:0044093 230 0.023
positive regulation of nucleic acid templated transcription GO:1903508 197 0.023
positive regulation of rna biosynthetic process GO:1902680 197 0.023
positive regulation of cell differentiation GO:0045597 217 0.023
positive regulation of rna metabolic process GO:0051254 203 0.023
ion homeostasis GO:0050801 212 0.023
regulation of neurogenesis GO:0050767 247 0.023
metal ion transport GO:0030001 289 0.022
cellular calcium ion homeostasis GO:0006874 160 0.022
response to extracellular stimulus GO:0009991 380 0.022
response to metal ion GO:0010038 253 0.022
positive regulation of catalytic activity GO:0043085 184 0.022
regulation of hormone levels GO:0010817 187 0.022
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.022
positive regulation of transcription dna templated GO:0045893 197 0.022
tissue development GO:0009888 252 0.022
regulation of secretion GO:0051046 224 0.022
cell projection organization GO:0030030 302 0.022
response to acid chemical GO:0001101 222 0.022
purine nucleotide metabolic process GO:0006163 229 0.022
secretion by cell GO:0032940 248 0.022
regulation of ion transport GO:0043269 245 0.022
organelle organization GO:0006996 266 0.021
regulation of protein metabolic process GO:0051246 289 0.021
lipid metabolic process GO:0006629 283 0.021
response to decreased oxygen levels GO:0036293 237 0.021
cation homeostasis GO:0055080 195 0.021
programmed cell death GO:0012501 392 0.021
neuron development GO:0048666 286 0.021
multicellular organismal reproductive process GO:0048609 233 0.021
Fly
negative regulation of multicellular organismal process GO:0051241 203 0.021
response to hypoxia GO:0001666 231 0.021
negative regulation of cell death GO:0060548 229 0.021
single organism catabolic process GO:0044712 283 0.021
blood circulation GO:0008015 183 0.021
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.021
head development GO:0060322 247 0.021
cellular homeostasis GO:0019725 252 0.021
positive regulation of nervous system development GO:0051962 178 0.021
positive regulation of neurogenesis GO:0050769 165 0.021
cellular component movement GO:0006928 248 0.021
cellular ion homeostasis GO:0006873 184 0.020
cellular cation homeostasis GO:0030003 180 0.020
cellular response to hormone stimulus GO:0032870 247 0.020
negative regulation of gene expression GO:0010629 199 0.020
neurological system process GO:0050877 219 0.020
regulation of cellular protein metabolic process GO:0032268 267 0.020
cellular response to nitrogen compound GO:1901699 210 0.020
nitrogen compound transport GO:0071705 229 0.020
cellular divalent inorganic cation homeostasis GO:0072503 162 0.020
cellular response to organonitrogen compound GO:0071417 197 0.020
cellular response to stress GO:0033554 269 0.019
positive regulation of cell development GO:0010720 176 0.019
macromolecular complex assembly GO:0065003 273 0.019
macromolecule localization GO:0033036 252 0.019
regulation of phosphorylation GO:0042325 248 0.019
positive regulation of cell communication GO:0010647 271 0.019
single organism organelle organization GO:1902589 180 0.019
calcium ion homeostasis GO:0055074 162 0.019
cellular metal ion homeostasis GO:0006875 172 0.019
negative regulation of cellular biosynthetic process GO:0031327 161 0.019
protein complex biogenesis GO:0070271 263 0.019
regulation of neuron differentiation GO:0045664 208 0.019
response to wounding GO:0009611 254 0.019
defense response GO:0006952 194 0.019
response to peptide hormone GO:0043434 278 0.018
cation transmembrane transport GO:0098655 263 0.018
response to growth factor GO:0070848 189 0.018
organonitrogen compound biosynthetic process GO:1901566 167 0.018
inorganic ion transmembrane transport GO:0098660 229 0.018
protein complex subunit organization GO:0071822 302 0.018
ras protein signal transduction GO:0007265 29 0.018
metal ion homeostasis GO:0055065 186 0.018
cellular response to lipid GO:0071396 201 0.018
regulation of cellular localization GO:0060341 263 0.018
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.018
protein complex assembly GO:0006461 263 0.018
negative regulation of biosynthetic process GO:0009890 168 0.018
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.018
multicellular organism reproduction GO:0032504 233 0.018
Fly
nucleoside metabolic process GO:0009116 179 0.018
hormone transport GO:0009914 121 0.018
intracellular transport GO:0046907 185 0.018
positive regulation of cellular amine metabolic process GO:0033240 3 0.018
positive regulation of signaling GO:0023056 270 0.018
response to nutrient GO:0007584 248 0.018
cytosolic calcium ion homeostasis GO:0051480 140 0.017
heart morphogenesis GO:0003007 3 0.017
cellular lipid metabolic process GO:0044255 208 0.017
regulation of protein modification process GO:0031399 194 0.017
response to carbohydrate GO:0009743 183 0.017
glycosyl compound metabolic process GO:1901657 182 0.017
aging GO:0007568 241 0.017
positive regulation of transport GO:0051050 245 0.017
muscle system process GO:0003012 115 0.017
positive regulation of cell death GO:0010942 184 0.017
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.017
nucleoside triphosphate metabolic process GO:0009141 144 0.017
ribonucleoside metabolic process GO:0009119 174 0.017
divalent inorganic cation homeostasis GO:0072507 165 0.017
regulation of protein phosphorylation GO:0001932 183 0.017
response to molecule of bacterial origin GO:0002237 194 0.017
single organism intracellular transport GO:1902582 166 0.017
regulation of secretion by cell GO:1903530 208 0.017
anterior posterior pattern specification GO:0009952 1 0.017
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.017
response to ethanol GO:0045471 162 0.017
anion transport GO:0006820 178 0.016
purine nucleoside metabolic process GO:0042278 169 0.016
negative regulation of cell proliferation GO:0008285 119 0.016
divalent inorganic cation transport GO:0072511 134 0.016
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.016
response to oxidative stress GO:0006979 186 0.016
cellular catabolic process GO:0044248 295 0.016
cell motility GO:0048870 202 0.016
purine ribonucleoside metabolic process GO:0046128 168 0.016
synaptic transmission GO:0007268 235 0.016
regulation of membrane potential GO:0042391 110 0.016
positive regulation of cellular component organization GO:0051130 200 0.016
divalent metal ion transport GO:0070838 132 0.016
developmental process involved in reproduction GO:0003006 159 0.016
localization of cell GO:0051674 202 0.016
response to other organism GO:0051707 220 0.016
positive regulation of cytosolic calcium ion concentration GO:0007204 122 0.016
organic cyclic compound catabolic process GO:1901361 175 0.016
negative regulation of apoptotic process GO:0043066 181 0.016
positive regulation of phosphorylation GO:0042327 177 0.016
response to glucose GO:0009749 136 0.015
calcium ion transport GO:0006816 131 0.015
negative regulation of cell communication GO:0010648 158 0.015
small gtpase mediated signal transduction GO:0007264 36 0.015
organonitrogen compound catabolic process GO:1901565 179 0.015
negative regulation of rna metabolic process GO:0051253 123 0.015
cellular response to growth factor stimulus GO:0071363 162 0.015
negative regulation of transcription dna templated GO:0045892 116 0.015
oxidation reduction process GO:0055114 304 0.015
protein oligomerization GO:0051259 191 0.015
cell migration GO:0016477 197 0.015
negative regulation of nucleic acid templated transcription GO:1903507 117 0.015
response to cytokine GO:0034097 215 0.015
heterocycle catabolic process GO:0046700 167 0.015
response to radiation GO:0009314 137 0.015
purine nucleoside triphosphate metabolic process GO:0009144 141 0.015
sexual reproduction GO:0019953 148 0.015
Fly
purine containing compound catabolic process GO:0072523 138 0.015
regulation of neuron projection development GO:0010975 161 0.015
rhythmic process GO:0048511 156 0.015
cellular nitrogen compound catabolic process GO:0044270 163 0.015
organophosphate biosynthetic process GO:0090407 143 0.015
regulation of blood circulation GO:1903522 110 0.015
response to corticosteroid GO:0031960 235 0.015
regulation of hydrolase activity GO:0051336 143 0.015
carbohydrate derivative biosynthetic process GO:1901137 124 0.015
response to estradiol GO:0032355 164 0.015
axis specification GO:0009798 4 0.015
aromatic compound catabolic process GO:0019439 168 0.015
gastrulation GO:0007369 2 0.014
response to ketone GO:1901654 182 0.014
response to biotic stimulus GO:0009607 226 0.014
response to external biotic stimulus GO:0043207 221 0.014
reproductive system development GO:0061458 128 0.014
response to lipopolysaccharide GO:0032496 191 0.014
positive regulation of protein metabolic process GO:0051247 178 0.014
negative regulation of response to stimulus GO:0048585 155 0.014
Fly
regulation of cell projection organization GO:0031344 175 0.014
signal release GO:0023061 145 0.014
cellular response to organic cyclic compound GO:0071407 202 0.014
response to glucocorticoid GO:0051384 223 0.014
female pregnancy GO:0007565 122 0.014
response to bacterium GO:0009617 200 0.014
locomotion GO:0040011 237 0.014
Fly
carbohydrate derivative catabolic process GO:1901136 147 0.014
gamete generation GO:0007276 124 0.014
positive regulation of neuron differentiation GO:0045666 126 0.014
inorganic cation transmembrane transport GO:0098662 202 0.014
nucleoside catabolic process GO:0009164 126 0.014
nucleoside phosphate catabolic process GO:1901292 140 0.014
response to hexose GO:0009746 144 0.014
cytoplasmic transport GO:0016482 115 0.014
immune system process GO:0002376 204 0.014
inflammatory response GO:0006954 150 0.014
mesoderm development GO:0007498 2 0.014
ribonucleoside triphosphate metabolic process GO:0009199 141 0.014
action potential GO:0001508 54 0.014
multi multicellular organism process GO:0044706 138 0.014
Fly
regulation of purine nucleotide metabolic process GO:1900542 115 0.014
muscle contraction GO:0006936 88 0.014
negative regulation of transport GO:0051051 136 0.013
regulation of metal ion transport GO:0010959 118 0.013
positive regulation of cell projection organization GO:0031346 111 0.013
purine ribonucleotide catabolic process GO:0009154 136 0.013
monovalent inorganic cation transport GO:0015672 172 0.013
negative regulation of rna biosynthetic process GO:1902679 118 0.013
purine nucleotide catabolic process GO:0006195 136 0.013
ribonucleoside catabolic process GO:0042454 126 0.013
regulation of synaptic transmission GO:0050804 141 0.013
regulation of nucleotide metabolic process GO:0006140 117 0.013
multicellular organismal signaling GO:0035637 44 0.013
positive regulation of apoptotic process GO:0043065 154 0.013
regulation of transferase activity GO:0051338 123 0.013
purine ribonucleoside triphosphate metabolic process GO:0009205 140 0.013
regulation of hormone secretion GO:0046883 106 0.013
regulation of cell migration GO:0030334 128 0.013
regulation of catabolic process GO:0009894 113 0.013
positive regulation of programmed cell death GO:0043068 157 0.013
regulation of neuron death GO:1901214 115 0.013
regulation of cellular component movement GO:0051270 150 0.013
reproductive structure development GO:0048608 128 0.013
cardiovascular system development GO:0072358 134 0.013
regulation of blood pressure GO:0008217 83 0.013
positive regulation of intracellular signal transduction GO:1902533 138 0.013
positive regulation of protein modification process GO:0031401 142 0.013
response to monosaccharide GO:0034284 159 0.013
positive regulation of purine nucleotide metabolic process GO:1900544 91 0.013
negative regulation of developmental process GO:0051093 125 0.013
negative regulation of molecular function GO:0044092 133 0.013
regulation of canonical wnt signaling pathway GO:0060828 4 0.013
regulation of kinase activity GO:0043549 117 0.013
ribonucleotide catabolic process GO:0009261 136 0.012
response to transition metal nanoparticle GO:1990267 122 0.012
purine nucleotide biosynthetic process GO:0006164 83 0.012
chromosome segregation GO:0007059 2 0.012
negative regulation of signaling GO:0023057 157 0.012
single organism carbohydrate metabolic process GO:0044723 118 0.012
nucleoside triphosphate catabolic process GO:0009143 123 0.012
purine ribonucleoside catabolic process GO:0046130 124 0.012
nucleotide catabolic process GO:0009166 139 0.012
positive regulation of cellular protein metabolic process GO:0032270 167 0.012
proteolysis GO:0006508 175 0.012
positive regulation of protein phosphorylation GO:0001934 135 0.012
nucleobase containing compound catabolic process GO:0034655 152 0.012
positive regulation of signal transduction GO:0009967 175 0.012
cellular response to alcohol GO:0097306 87 0.012
circulatory system development GO:0072359 134 0.012
ribonucleoside triphosphate catabolic process GO:0009203 122 0.012
regeneration GO:0031099 163 0.012
transmission of nerve impulse GO:0019226 42 0.012
organophosphate catabolic process GO:0046434 148 0.012
response to vitamin GO:0033273 131 0.012
positive regulation of secretion GO:0051047 140 0.012
glycosyl compound catabolic process GO:1901658 126 0.012
protein localization GO:0008104 191 0.012
regulation of anatomical structure morphogenesis GO:0022603 141 0.012
behavior GO:0007610 205 0.012
Fly
positive regulation of hydrolase activity GO:0051345 86 0.012
response to toxic substance GO:0009636 133 0.012
regulation of anatomical structure size GO:0090066 135 0.012
nucleotide biosynthetic process GO:0009165 98 0.012
signal transduction by phosphorylation GO:0023014 144 0.012
neuronal action potential GO:0019228 35 0.012
cellular response to steroid hormone stimulus GO:0071383 93 0.012
sensory perception GO:0007600 101 0.012
regulation of cell motility GO:2000145 131 0.012
peptide transport GO:0015833 97 0.012
positive regulation of nucleotide metabolic process GO:0045981 91 0.012
dna metabolic process GO:0006259 96 0.012
gland development GO:0048732 155 0.012
carbohydrate metabolic process GO:0005975 130 0.012
cellular response to peptide GO:1901653 133 0.012
peptidyl amino acid modification GO:0018193 126 0.012
purine ribonucleoside triphosphate catabolic process GO:0009207 122 0.012
regulation of cellular catabolic process GO:0031329 101 0.012
hormone secretion GO:0046879 115 0.012
mapk cascade GO:0000165 140 0.012
positive regulation of neuron projection development GO:0010976 99 0.011
ribose phosphate biosynthetic process GO:0046390 87 0.011
purine nucleoside catabolic process GO:0006152 124 0.011
establishment of protein localization GO:0045184 141 0.011
ribonucleotide biosynthetic process GO:0009260 85 0.011
growth GO:0040007 165 0.011
purine containing compound biosynthetic process GO:0072522 85 0.011
cell adhesion GO:0007155 110 0.011
protein transport GO:0015031 132 0.011
spindle organization GO:0007051 2 0.011
sex differentiation GO:0007548 113 0.011
amide transport GO:0042886 105 0.011
vascular process in circulatory system GO:0003018 96 0.011
eye morphogenesis GO:0048592 4 0.011
regulation of homeostatic process GO:0032844 101 0.011
reactive oxygen species metabolic process GO:0072593 37 0.011
organic anion transport GO:0015711 132 0.011
regulation of mapk cascade GO:0043408 116 0.011
monocarboxylic acid metabolic process GO:0032787 152 0.011
positive regulation of secretion by cell GO:1903532 128 0.011
negative regulation of protein metabolic process GO:0051248 114 0.011
response to reactive oxygen species GO:0000302 120 0.011
cellular response to cytokine stimulus GO:0071345 127 0.011
organ morphogenesis GO:0009887 75 0.011
regulation of body fluid levels GO:0050878 90 0.011
lipid storage GO:0019915 1 0.011
liver development GO:0001889 90 0.011
embryonic pattern specification GO:0009880 1 0.011
formation of primary germ layer GO:0001704 1 0.011
positive regulation of ion transport GO:0043270 94 0.011
heart contraction GO:0060047 57 0.011
purine ribonucleotide biosynthetic process GO:0009152 81 0.011
response to alkaloid GO:0043279 132 0.011
dephosphorylation GO:0016311 98 0.011
purine nucleoside triphosphate catabolic process GO:0009146 122 0.011
sequestering of calcium ion GO:0051208 8 0.011
peptide secretion GO:0002790 86 0.011
peptide hormone secretion GO:0030072 84 0.011
lipid biosynthetic process GO:0008610 128 0.011
negative regulation of innate immune response GO:0045824 4 0.011
forebrain development GO:0030900 98 0.011
regulation of response to stress GO:0080134 126 0.011
cellular response to acid chemical GO:0071229 75 0.011
sequestering of metal ion GO:0051238 9 0.010
maintenance of location GO:0051235 17 0.010
membrane organization GO:0061024 94 0.010
carboxylic acid transport GO:0046942 115 0.010
regulation of calcium ion transport GO:0051924 77 0.010
regulation of response to external stimulus GO:0032101 106 0.010
carbohydrate homeostasis GO:0033500 75 0.010
negative regulation of catalytic activity GO:0043086 103 0.010
regulation of immune system process GO:0002682 123 0.010
reactive oxygen species biosynthetic process GO:1903409 8 0.010
actin filament based process GO:0030029 86 0.010
cellular component morphogenesis GO:0032989 155 0.010
cell cell signaling involved in cell fate commitment GO:0045168 2 0.010
response to insulin GO:0032868 133 0.010
limb morphogenesis GO:0035108 4 0.010
nucleoside phosphate biosynthetic process GO:1901293 102 0.010
appendage morphogenesis GO:0035107 4 0.010
regulation of locomotion GO:0040012 148 0.010
Fly
rho protein signal transduction GO:0007266 11 0.010

Kctd8 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.033
nervous system disease DOID:863 0 0.033
musculoskeletal system disease DOID:17 0 0.023
sensory system disease DOID:0050155 0 0.016
central nervous system disease DOID:331 0 0.014
disease of metabolism DOID:0014667 0 0.012
myopathy DOID:423 0 0.012
muscular disease DOID:0080000 0 0.012
muscle tissue disease DOID:66 0 0.012
eye and adnexa disease DOID:1492 0 0.010
eye disease DOID:5614 0 0.010