Rattus norvegicus

54 known processes

Neu1

sialidase 1 (lysosomal sialidase)

Neu1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
organic anion transport GO:0015711 132 0.098
intracellular signal transduction GO:0035556 314 0.081
response to nutrient levels GO:0031667 370 0.079
catabolic process GO:0009056 351 0.070
anion transport GO:0006820 178 0.066
response to extracellular stimulus GO:0009991 380 0.059
response to external biotic stimulus GO:0043207 221 0.059
response to biotic stimulus GO:0009607 226 0.050
cellular response to oxygen containing compound GO:1901701 386 0.050
carboxylic acid metabolic process GO:0019752 289 0.049
cellular catabolic process GO:0044248 295 0.049
response to corticosteroid GO:0031960 235 0.047
response to glucocorticoid GO:0051384 223 0.046
cellular response to stress GO:0033554 269 0.046
response to other organism GO:0051707 220 0.046
oxoacid metabolic process GO:0043436 290 0.042
cellular amino acid metabolic process GO:0006520 107 0.040
organic acid metabolic process GO:0006082 292 0.040
response to carbohydrate GO:0009743 183 0.037
single organism catabolic process GO:0044712 283 0.036
response to lipopolysaccharide GO:0032496 191 0.036
secretion GO:0046903 307 0.035
positive regulation of apoptotic process GO:0043065 154 0.035
regulation of cellular amino acid metabolic process GO:0006521 2 0.033
regulation of cellular protein metabolic process GO:0032268 267 0.032
aging GO:0007568 241 0.032
carboxylic acid transport GO:0046942 115 0.032
carbohydrate derivative metabolic process GO:1901135 346 0.031
response to monosaccharide GO:0034284 159 0.031
regulation of cellular ketone metabolic process GO:0010565 27 0.031
macromolecular complex subunit organization GO:0043933 339 0.031
regulation of programmed cell death GO:0043067 341 0.031
response to decreased oxygen levels GO:0036293 237 0.031
regulation of intracellular signal transduction GO:1902531 218 0.030
chemical homeostasis GO:0048878 292 0.030
positive regulation of programmed cell death GO:0043068 157 0.029
protein complex subunit organization GO:0071822 302 0.029
regulation of system process GO:0044057 208 0.029
response to nutrient GO:0007584 248 0.029
cellular ketone metabolic process GO:0042180 51 0.029
nucleotide metabolic process GO:0009117 279 0.028
regulation of hormone levels GO:0010817 187 0.028
neuron projection development GO:0031175 273 0.028
organic substance catabolic process GO:1901575 316 0.028
regulation of secretion GO:0051046 224 0.027
organophosphate catabolic process GO:0046434 148 0.027
regulation of cellular amine metabolic process GO:0033238 8 0.027
nucleoside phosphate metabolic process GO:0006753 283 0.026
positive regulation of cell death GO:0010942 184 0.026
organelle organization GO:0006996 266 0.026
regulation of apoptotic process GO:0042981 335 0.026
positive regulation of cell communication GO:0010647 271 0.026
response to molecule of bacterial origin GO:0002237 194 0.026
purine containing compound metabolic process GO:0072521 253 0.026
cellular amine metabolic process GO:0044106 38 0.025
positive regulation of catalytic activity GO:0043085 184 0.024
response to estradiol GO:0032355 164 0.024
cation homeostasis GO:0055080 195 0.024
apoptotic process GO:0006915 381 0.024
organic acid transport GO:0015849 116 0.024
positive regulation of rna metabolic process GO:0051254 203 0.024
response to metal ion GO:0010038 253 0.023
head development GO:0060322 247 0.023
cellular response to endogenous stimulus GO:0071495 377 0.023
reproductive process GO:0022414 372 0.023
regulation of cellular component organization GO:0051128 368 0.023
protein localization GO:0008104 191 0.023
response to cytokine GO:0034097 215 0.023
small gtpase mediated signal transduction GO:0007264 36 0.022
hormone transport GO:0009914 121 0.022
homeostatic process GO:0042592 331 0.022
regulation of catalytic activity GO:0050790 304 0.022
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.022
response to peptide GO:1901652 292 0.021
macromolecule localization GO:0033036 252 0.021
neuron development GO:0048666 286 0.021
response to glucose GO:0009749 136 0.021
response to oxidative stress GO:0006979 186 0.021
cation transport GO:0006812 382 0.021
response to inorganic substance GO:0010035 377 0.021
response to bacterium GO:0009617 200 0.021
neurological system process GO:0050877 219 0.021
positive regulation of response to stimulus GO:0048584 285 0.021
response to ketone GO:1901654 182 0.020
neuron differentiation GO:0030182 368 0.020
multi organism reproductive process GO:0044703 262 0.020
ras protein signal transduction GO:0007265 29 0.020
lipid localization GO:0010876 62 0.020
multicellular organism reproduction GO:0032504 233 0.020
positive regulation of molecular function GO:0044093 230 0.020
positive regulation of signal transduction GO:0009967 175 0.020
regulation of signal transduction GO:0009966 318 0.020
nucleotide catabolic process GO:0009166 139 0.020
amino acid transport GO:0006865 70 0.020
signal release GO:0023061 145 0.020
lipid transport GO:0006869 61 0.019
positive regulation of phosphorus metabolic process GO:0010562 262 0.019
organonitrogen compound catabolic process GO:1901565 179 0.019
nucleobase containing compound catabolic process GO:0034655 152 0.019
response to hypoxia GO:0001666 231 0.019
tissue development GO:0009888 252 0.019
programmed cell death GO:0012501 392 0.019
reproduction GO:0000003 245 0.019
regulation of neuron projection development GO:0010975 161 0.018
cellular response to external stimulus GO:0071496 118 0.018
nucleobase containing small molecule metabolic process GO:0055086 316 0.018
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.018
regulation of secretion by cell GO:1903530 208 0.018
cellular homeostasis GO:0019725 252 0.018
single organism reproductive process GO:0044702 297 0.018
multicellular organism growth GO:0035264 1 0.018
cellular cation homeostasis GO:0030003 180 0.018
alpha amino acid metabolic process GO:1901605 71 0.018
positive regulation of cellular amine metabolic process GO:0033240 3 0.018
inorganic ion transmembrane transport GO:0098660 229 0.017
response to acid chemical GO:0001101 222 0.017
nitrogen compound transport GO:0071705 229 0.017
regulation of membrane potential GO:0042391 110 0.017
cellular chemical homeostasis GO:0055082 247 0.017
regulation of cell differentiation GO:0045595 320 0.017
multicellular organismal reproductive process GO:0048609 233 0.017
positive regulation of cellular component organization GO:0051130 200 0.017
cellular response to organonitrogen compound GO:0071417 197 0.017
ribose phosphate metabolic process GO:0019693 235 0.017
response to radiation GO:0009314 137 0.017
transmembrane transport GO:0055085 412 0.017
regulation of hydrolase activity GO:0051336 143 0.017
regulation of rna metabolic process GO:0051252 391 0.016
response to hexose GO:0009746 144 0.016
ion homeostasis GO:0050801 212 0.016
heterocycle catabolic process GO:0046700 167 0.016
regulation of molecular function GO:0065009 398 0.016
response to oxygen levels GO:0070482 265 0.016
anatomical structure morphogenesis GO:0009653 298 0.016
protein oligomerization GO:0051259 191 0.016
response to temperature stimulus GO:0009266 94 0.016
response to toxic substance GO:0009636 133 0.016
protein complex assembly GO:0006461 263 0.016
regulation of protein metabolic process GO:0051246 289 0.016
positive regulation of phosphate metabolic process GO:0045937 262 0.016
positive regulation of biosynthetic process GO:0009891 319 0.016
secretion by cell GO:0032940 248 0.016
ribonucleoside catabolic process GO:0042454 126 0.016
regulation of cellular response to stress GO:0080135 49 0.015
proteolysis GO:0006508 175 0.015
purine nucleotide catabolic process GO:0006195 136 0.015
lipid metabolic process GO:0006629 283 0.015
nucleoside phosphate catabolic process GO:1901292 140 0.015
cellular response to hormone stimulus GO:0032870 247 0.015
neuronal action potential GO:0019228 35 0.015
cellular component biogenesis GO:0044085 368 0.015
regulation of transcription dna templated GO:0006355 374 0.015
organic cyclic compound catabolic process GO:1901361 175 0.015
response to wounding GO:0009611 254 0.015
regulation of body fluid levels GO:0050878 90 0.015
defense response GO:0006952 194 0.015
regulation of phosphorus metabolic process GO:0051174 349 0.015
cellular response to extracellular stimulus GO:0031668 73 0.015
response to peptide hormone GO:0043434 278 0.015
positive regulation of protein phosphorylation GO:0001934 135 0.014
positive regulation of cellular protein metabolic process GO:0032270 167 0.014
cellular response to organic cyclic compound GO:0071407 202 0.014
positive regulation of signaling GO:0023056 270 0.014
regulation of kinase activity GO:0043549 117 0.014
response to vitamin GO:0033273 131 0.014
aromatic compound catabolic process GO:0019439 168 0.014
metal ion transport GO:0030001 289 0.014
nucleic acid templated transcription GO:0097659 379 0.014
regulation of cellular localization GO:0060341 263 0.014
amine metabolic process GO:0009308 38 0.014
positive regulation of protein metabolic process GO:0051247 178 0.014
negative regulation of metabolic process GO:0009892 331 0.014
monocarboxylic acid transport GO:0015718 52 0.013
positive regulation of transferase activity GO:0051347 81 0.013
cellular component assembly GO:0022607 360 0.013
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.013
regulation of protein modification process GO:0031399 194 0.013
localization of cell GO:0051674 202 0.013
negative regulation of cellular protein metabolic process GO:0032269 106 0.013
cell adhesion GO:0007155 110 0.013
membrane organization GO:0061024 94 0.013
transcription from rna polymerase ii promoter GO:0006366 252 0.013
oligopeptide transport GO:0006857 4 0.013
nucleoside triphosphate catabolic process GO:0009143 123 0.013
female pregnancy GO:0007565 122 0.013
cation transmembrane transport GO:0098655 263 0.013
nucleoside triphosphate metabolic process GO:0009141 144 0.013
glycosyl compound metabolic process GO:1901657 182 0.013
cellular amide metabolic process GO:0043603 44 0.013
purine nucleotide metabolic process GO:0006163 229 0.013
response to mechanical stimulus GO:0009612 134 0.013
cellular ion homeostasis GO:0006873 184 0.013
regulation of cell projection organization GO:0031344 175 0.013
protein phosphorylation GO:0006468 345 0.013
positive regulation of intracellular signal transduction GO:1902533 138 0.013
negative regulation of signaling GO:0023057 157 0.013
single organism biosynthetic process GO:0044711 342 0.013
positive regulation of cellular catabolic process GO:0031331 71 0.012
metal ion homeostasis GO:0055065 186 0.012
response to starvation GO:0042594 59 0.012
single organism organelle organization GO:1902589 180 0.012
response to ethanol GO:0045471 162 0.012
brain development GO:0007420 247 0.012
cellular response to nitrogen compound GO:1901699 210 0.012
response to estrogen GO:0043627 232 0.012
single organism membrane organization GO:0044802 74 0.012
response to heat GO:0009408 60 0.012
peptide transport GO:0015833 97 0.012
lipid storage GO:0019915 1 0.012
purine ribonucleotide metabolic process GO:0009150 227 0.012
anterior posterior pattern specification GO:0009952 1 0.012
cellular nitrogen compound catabolic process GO:0044270 163 0.012
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.012
cell projection organization GO:0030030 302 0.012
negative regulation of transport GO:0051051 136 0.012
regulation of protein kinase activity GO:0045859 105 0.012
response to purine containing compound GO:0014074 126 0.012
regulation of cellular component biogenesis GO:0044087 86 0.012
negative regulation of macromolecule metabolic process GO:0010605 260 0.012
purine nucleoside metabolic process GO:0042278 169 0.012
organophosphate metabolic process GO:0019637 370 0.011
gastrulation GO:0007369 2 0.011
hormone secretion GO:0046879 115 0.011
positive regulation of cell differentiation GO:0045597 217 0.011
cellular response to insulin stimulus GO:0032869 81 0.011
monovalent inorganic cation transport GO:0015672 172 0.011
regulation of transferase activity GO:0051338 123 0.011
axis specification GO:0009798 4 0.011
positive regulation of protein modification process GO:0031401 142 0.011
rna biosynthetic process GO:0032774 380 0.011
negative regulation of gene expression GO:0010629 199 0.011
regulation of cellular catabolic process GO:0031329 101 0.011
divalent inorganic cation homeostasis GO:0072507 165 0.011
purine ribonucleotide catabolic process GO:0009154 136 0.011
cellular response to lipid GO:0071396 201 0.011
regulation of nucleic acid templated transcription GO:1903506 380 0.011
antibiotic transport GO:0042891 2 0.011
gamete generation GO:0007276 124 0.011
rna metabolic process GO:0016070 406 0.011
sexual reproduction GO:0019953 148 0.011
protein complex biogenesis GO:0070271 263 0.011
toxin transport GO:1901998 3 0.011
dna metabolic process GO:0006259 96 0.011
negative regulation of protein metabolic process GO:0051248 114 0.011
cellular response to peptide GO:1901653 133 0.011
cytosolic calcium ion homeostasis GO:0051480 140 0.010
carboxylic acid biosynthetic process GO:0046394 83 0.010
macromolecular complex assembly GO:0065003 273 0.010
ion transmembrane transport GO:0034220 365 0.010
amide transport GO:0042886 105 0.010
regulation of growth GO:0040008 105 0.010
regulation of multicellular organismal development GO:2000026 376 0.010
cholesterol homeostasis GO:0042632 3 0.010
growth GO:0040007 165 0.010
synaptic transmission GO:0007268 235 0.010
response to reactive oxygen species GO:0000302 120 0.010
purine ribonucleoside catabolic process GO:0046130 124 0.010
positive regulation of phosphorylation GO:0042327 177 0.010

Neu1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.036
disease of anatomical entity DOID:7 0 0.028
nervous system disease DOID:863 0 0.028
inherited metabolic disorder DOID:655 0 0.028
musculoskeletal system disease DOID:17 0 0.021
bone disease DOID:0080001 0 0.012
connective tissue disease DOID:65 0 0.012
central nervous system disease DOID:331 0 0.011
brain disease DOID:936 0 0.011