Rattus norvegicus

0 known processes

Nepn

nephrocan

(Aliases: RGD1307755)

Nepn biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
transmembrane transport GO:0055085 412 0.128
response to nutrient GO:0007584 248 0.106
response to extracellular stimulus GO:0009991 380 0.097
programmed cell death GO:0012501 392 0.096
organic substance catabolic process GO:1901575 316 0.087
response to peptide GO:1901652 292 0.085
apoptotic process GO:0006915 381 0.079
regulation of cellular component movement GO:0051270 150 0.074
macromolecular complex subunit organization GO:0043933 339 0.068
regulation of cellular protein metabolic process GO:0032268 267 0.066
response to bacterium GO:0009617 200 0.064
response to wounding GO:0009611 254 0.060
cellular response to endogenous stimulus GO:0071495 377 0.058
catabolic process GO:0009056 351 0.058
negative regulation of cell death GO:0060548 229 0.055
immune system process GO:0002376 204 0.055
negative regulation of metabolic process GO:0009892 331 0.055
regulation of protein metabolic process GO:0051246 289 0.055
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.055
positive regulation of cellular component movement GO:0051272 102 0.054
response to hypoxia GO:0001666 231 0.053
response to nutrient levels GO:0031667 370 0.053
aging GO:0007568 241 0.053
tissue development GO:0009888 252 0.052
response to decreased oxygen levels GO:0036293 237 0.051
neuron differentiation GO:0030182 368 0.050
cellular component movement GO:0006928 248 0.049
response to molecule of bacterial origin GO:0002237 194 0.049
cation transport GO:0006812 382 0.049
regulation of cell development GO:0060284 263 0.048
biological adhesion GO:0022610 110 0.048
proteolysis GO:0006508 175 0.046
negative regulation of multicellular organismal process GO:0051241 203 0.046
cell migration GO:0016477 197 0.046
amine metabolic process GO:0009308 38 0.046
rna metabolic process GO:0016070 406 0.045
regulation of apoptotic process GO:0042981 335 0.044
positive regulation of molecular function GO:0044093 230 0.044
regulation of cell proliferation GO:0042127 359 0.044
cell motility GO:0048870 202 0.043
positive regulation of biosynthetic process GO:0009891 319 0.042
transcription dna templated GO:0006351 377 0.042
anatomical structure morphogenesis GO:0009653 298 0.042
regulation of molecular function GO:0065009 398 0.042
wound healing GO:0042060 122 0.042
rna biosynthetic process GO:0032774 380 0.041
nucleic acid templated transcription GO:0097659 379 0.041
cellular amino acid metabolic process GO:0006520 107 0.041
response to oxidative stress GO:0006979 186 0.041
cellular response to hormone stimulus GO:0032870 247 0.041
single organism biosynthetic process GO:0044711 342 0.041
response to external biotic stimulus GO:0043207 221 0.040
response to acid chemical GO:0001101 222 0.040
response to lipopolysaccharide GO:0032496 191 0.040
response to peptide hormone GO:0043434 278 0.040
growth GO:0040007 165 0.039
regulation of transcription dna templated GO:0006355 374 0.039
response to oxygen levels GO:0070482 265 0.039
regeneration GO:0031099 163 0.039
macromolecular complex assembly GO:0065003 273 0.037
response to biotic stimulus GO:0009607 226 0.035
positive regulation of cell proliferation GO:0008284 249 0.035
homeostatic process GO:0042592 331 0.035
positive regulation of gene expression GO:0010628 244 0.035
positive regulation of cell communication GO:0010647 271 0.034
cellular amine metabolic process GO:0044106 38 0.034
organonitrogen compound catabolic process GO:1901565 179 0.034
regulation of cell differentiation GO:0045595 320 0.033
protein complex assembly GO:0006461 263 0.033
response to cytokine GO:0034097 215 0.033
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.033
positive regulation of cellular biosynthetic process GO:0031328 295 0.033
positive regulation of developmental process GO:0051094 283 0.033
response to vitamin GO:0033273 131 0.032
response to organophosphorus GO:0046683 102 0.032
positive regulation of response to stimulus GO:0048584 285 0.032
negative regulation of apoptotic process GO:0043066 181 0.032
organic acid metabolic process GO:0006082 292 0.032
regulation of programmed cell death GO:0043067 341 0.032
regulation of nucleic acid templated transcription GO:1903506 380 0.032
regulation of locomotion GO:0040012 148 0.031
regulation of system process GO:0044057 208 0.030
response to inorganic substance GO:0010035 377 0.030
positive regulation of phosphate metabolic process GO:0045937 262 0.030
regulation of neuron death GO:1901214 115 0.030
positive regulation of protein metabolic process GO:0051247 178 0.029
developmental growth GO:0048589 100 0.029
localization of cell GO:0051674 202 0.029
cellular response to oxidative stress GO:0034599 76 0.029
chemical homeostasis GO:0048878 292 0.029
response to glucocorticoid GO:0051384 223 0.028
regulation of multicellular organismal development GO:2000026 376 0.028
regulation of cellular amine metabolic process GO:0033238 8 0.028
metal ion transport GO:0030001 289 0.028
oxoacid metabolic process GO:0043436 290 0.027
locomotion GO:0040011 237 0.027
regulation of anatomical structure morphogenesis GO:0022603 141 0.027
cellular homeostasis GO:0019725 252 0.027
negative regulation of neuron death GO:1901215 69 0.027
response to purine containing compound GO:0014074 126 0.027
central nervous system development GO:0007417 311 0.027
response to hexose GO:0009746 144 0.027
regulation of catalytic activity GO:0050790 304 0.027
positive regulation of catalytic activity GO:0043085 184 0.027
cellular response to nitrogen compound GO:1901699 210 0.027
regulation of cellular component organization GO:0051128 368 0.026
response to other organism GO:0051707 220 0.026
regulation of cell projection organization GO:0031344 175 0.026
regulation of cellular ketone metabolic process GO:0010565 27 0.026
positive regulation of cellular amine metabolic process GO:0033240 3 0.025
multi organism reproductive process GO:0044703 262 0.025
positive regulation of cell differentiation GO:0045597 217 0.025
regulation of rna metabolic process GO:0051252 391 0.025
regulation of rna biosynthetic process GO:2001141 381 0.025
cellular response to steroid hormone stimulus GO:0071383 93 0.025
neuron death GO:0070997 127 0.025
regulation of hormone levels GO:0010817 187 0.024
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.024
brain development GO:0007420 247 0.024
response to insulin GO:0032868 133 0.024
response to corticosteroid GO:0031960 235 0.024
neuron projection development GO:0031175 273 0.024
neuron development GO:0048666 286 0.024
regulation of cell motility GO:2000145 131 0.024
cellular component biogenesis GO:0044085 368 0.024
cellular response to organonitrogen compound GO:0071417 197 0.024
response to estrogen GO:0043627 232 0.024
cellular component assembly GO:0022607 360 0.023
cellular catabolic process GO:0044248 295 0.023
protein phosphorylation GO:0006468 345 0.023
regulation of neuron differentiation GO:0045664 208 0.023
cellular response to growth factor stimulus GO:0071363 162 0.023
protein maturation GO:0051604 68 0.023
response to carbohydrate GO:0009743 183 0.023
regulation of cellular amino acid metabolic process GO:0006521 2 0.023
cellular chemical homeostasis GO:0055082 247 0.022
positive regulation of phosphorus metabolic process GO:0010562 262 0.022
cellular response to stress GO:0033554 269 0.022
cellular response to oxygen containing compound GO:1901701 386 0.022
negative regulation of molecular function GO:0044092 133 0.022
regulation of neurogenesis GO:0050767 247 0.022
response to camp GO:0051591 91 0.022
blood circulation GO:0008015 183 0.022
intracellular signal transduction GO:0035556 314 0.022
regulation of protein phosphorylation GO:0001932 183 0.022
positive regulation of cellular protein metabolic process GO:0032270 167 0.022
regulation of secretion GO:0051046 224 0.022
cellular ketone metabolic process GO:0042180 51 0.022
cell activation GO:0001775 97 0.022
negative regulation of gene expression GO:0010629 199 0.022
regulation of protein modification process GO:0031399 194 0.021
negative regulation of developmental process GO:0051093 125 0.021
regulation of protein maturation GO:1903317 50 0.021
response to reactive oxygen species GO:0000302 120 0.021
negative regulation of macromolecule metabolic process GO:0010605 260 0.021
positive regulation of protein modification process GO:0031401 142 0.021
response to glucose GO:0009749 136 0.021
regulation of proteolysis GO:0030162 66 0.021
negative regulation of cellular metabolic process GO:0031324 281 0.021
sex differentiation GO:0007548 113 0.021
peptidyl amino acid modification GO:0018193 126 0.021
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.021
regulation of epithelial cell proliferation GO:0050678 49 0.021
regulation of phosphorus metabolic process GO:0051174 349 0.021
response to ethanol GO:0045471 162 0.021
regulation of phosphorylation GO:0042325 248 0.021
cell growth GO:0016049 104 0.021
small molecule biosynthetic process GO:0044283 124 0.021
embryonic appendage morphogenesis GO:0035113 4 0.020
neurological system process GO:0050877 219 0.020
negative regulation of programmed cell death GO:0043069 183 0.020
carboxylic acid metabolic process GO:0019752 289 0.020
multicellular organismal reproductive process GO:0048609 233 0.020
negative regulation of protein metabolic process GO:0051248 114 0.020
regulation of ion transport GO:0043269 245 0.020
regulation of secretion by cell GO:1903530 208 0.020
rhythmic process GO:0048511 156 0.020
regulation of hydrolase activity GO:0051336 143 0.019
cellular response to peptide GO:1901653 133 0.019
regulation of cell morphogenesis GO:0022604 77 0.019
head development GO:0060322 247 0.019
protein complex subunit organization GO:0071822 302 0.019
peptidyl tyrosine modification GO:0018212 72 0.019
regulation of cell morphogenesis involved in differentiation GO:0010769 72 0.019
smooth muscle cell proliferation GO:0048659 77 0.019
positive regulation of phosphorylation GO:0042327 177 0.019
ion transmembrane transport GO:0034220 365 0.019
cardiovascular system development GO:0072358 134 0.019
positive regulation of rna biosynthetic process GO:1902680 197 0.019
regulation of cell migration GO:0030334 128 0.019
regulation of signal transduction GO:0009966 318 0.018
muscle tissue development GO:0060537 58 0.018
regulation of phosphate metabolic process GO:0019220 349 0.018
carbohydrate metabolic process GO:0005975 130 0.018
single organism catabolic process GO:0044712 283 0.018
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.018
reproductive structure development GO:0048608 128 0.018
reactive oxygen species metabolic process GO:0072593 37 0.018
cellular response to organic cyclic compound GO:0071407 202 0.018
positive regulation of programmed cell death GO:0043068 157 0.018
regulation of growth GO:0040008 105 0.018
regulation of nervous system development GO:0051960 264 0.018
regulation of blood circulation GO:1903522 110 0.018
muscle structure development GO:0061061 87 0.018
carbohydrate derivative metabolic process GO:1901135 346 0.018
cation homeostasis GO:0055080 195 0.018
response to monosaccharide GO:0034284 159 0.018
reproductive process GO:0022414 372 0.018
positive regulation of transport GO:0051050 245 0.018
circulatory system process GO:0003013 183 0.018
muscle cell proliferation GO:0033002 84 0.017
cell cell signaling GO:0007267 335 0.017
positive regulation of signal transduction GO:0009967 175 0.017
positive regulation of cell development GO:0010720 176 0.017
positive regulation of transcription dna templated GO:0045893 197 0.017
regulation of response to external stimulus GO:0032101 106 0.017
actin filament based process GO:0030029 86 0.017
regulation of response to wounding GO:1903034 69 0.017
peptidyl tyrosine phosphorylation GO:0018108 72 0.017
multi multicellular organism process GO:0044706 138 0.017
protein oligomerization GO:0051259 191 0.017
renal system development GO:0072001 67 0.016
reactive oxygen species biosynthetic process GO:1903409 8 0.016
positive regulation of hydrolase activity GO:0051345 86 0.016
positive regulation of smooth muscle cell proliferation GO:0048661 51 0.016
positive regulation of protein phosphorylation GO:0001934 135 0.016
protein complex biogenesis GO:0070271 263 0.016
single organism reproductive process GO:0044702 297 0.016
cellular component morphogenesis GO:0032989 155 0.016
cell adhesion GO:0007155 110 0.016
positive regulation of nucleic acid templated transcription GO:1903508 197 0.016
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.016
positive regulation of neuron differentiation GO:0045666 126 0.016
development of primary sexual characteristics GO:0045137 107 0.016
response to chromate GO:0046687 3 0.016
cell morphogenesis involved in differentiation GO:0000904 119 0.015
reproduction GO:0000003 245 0.015
cellular response to reactive oxygen species GO:0034614 55 0.015
cell projection organization GO:0030030 302 0.015
multicellular organismal signaling GO:0035637 44 0.015
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.015
cellular response to external stimulus GO:0071496 118 0.015
positive regulation of secretion by cell GO:1903532 128 0.015
negative regulation of protein maturation GO:1903318 47 0.015
regulation of intracellular signal transduction GO:1902531 218 0.015
regulation of blood vessel size GO:0050880 89 0.015
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.015
positive regulation of neurogenesis GO:0050769 165 0.015
inorganic ion transmembrane transport GO:0098660 229 0.015
response to hydrogen peroxide GO:0042542 89 0.015
regulation of anatomical structure size GO:0090066 135 0.015
cellular response to corticosteroid stimulus GO:0071384 69 0.015
response to axon injury GO:0048678 59 0.014
response to estradiol GO:0032355 164 0.014
multicellular organism reproduction GO:0032504 233 0.014
transcription from rna polymerase ii promoter GO:0006366 252 0.014
protein heterooligomerization GO:0051291 89 0.014
regulation of reactive oxygen species metabolic process GO:2000377 26 0.014
neuron projection morphogenesis GO:0048812 122 0.014
positive regulation of nervous system development GO:0051962 178 0.014
positive regulation of apoptotic process GO:0043065 154 0.014
muscle system process GO:0003012 115 0.014
regulation of membrane potential GO:0042391 110 0.014
secretion GO:0046903 307 0.014
response to mechanical stimulus GO:0009612 134 0.014
immune response GO:0006955 104 0.014
secretion by cell GO:0032940 248 0.014
nucleobase containing small molecule metabolic process GO:0055086 316 0.013
organ regeneration GO:0031100 101 0.013
organic hydroxy compound metabolic process GO:1901615 115 0.013
action potential GO:0001508 54 0.013
positive regulation of rna metabolic process GO:0051254 203 0.013
regulation of neuron projection development GO:0010975 161 0.013
glucose homeostasis GO:0042593 75 0.013
positive regulation of kinase activity GO:0033674 77 0.013
positive regulation of multicellular organismal process GO:0051240 387 0.013
epithelium development GO:0060429 96 0.013
response to amino acid GO:0043200 75 0.013
response to transition metal nanoparticle GO:1990267 122 0.013
cell morphogenesis GO:0000902 142 0.013
regulation of amine transport GO:0051952 54 0.013
gliogenesis GO:0042063 93 0.013
transmission of nerve impulse GO:0019226 42 0.013
axon development GO:0061564 96 0.013
negative regulation of peptidase activity GO:0010466 38 0.013
cell part morphogenesis GO:0032990 123 0.012
ion homeostasis GO:0050801 212 0.012
regulation of transferase activity GO:0051338 123 0.012
response to activity GO:0014823 73 0.012
cellular response to lipid GO:0071396 201 0.012
protein processing GO:0016485 68 0.012
response to growth factor GO:0070848 189 0.012
negative regulation of catalytic activity GO:0043086 103 0.012
male sex differentiation GO:0046661 64 0.012
regulation of peptidase activity GO:0052547 55 0.012
purine nucleoside metabolic process GO:0042278 169 0.012
positive regulation of transferase activity GO:0051347 81 0.012
nitrogen compound transport GO:0071705 229 0.012
cellular response to peptide hormone stimulus GO:0071375 120 0.012
cellular lipid metabolic process GO:0044255 208 0.012
regulation of stem cell differentiation GO:2000736 2 0.012
circadian rhythm GO:0007623 88 0.012
limb morphogenesis GO:0035108 4 0.012
response to toxic substance GO:0009636 133 0.012
male gonad development GO:0008584 59 0.012
metal ion homeostasis GO:0055065 186 0.012
ras protein signal transduction GO:0007265 29 0.012
regulation of immunoglobulin production GO:0002637 4 0.012
organonitrogen compound biosynthetic process GO:1901566 167 0.011
defense response GO:0006952 194 0.011
negative regulation of cell differentiation GO:0045596 99 0.011
divalent inorganic cation homeostasis GO:0072507 165 0.011
small gtpase mediated signal transduction GO:0007264 36 0.011
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.011
monovalent inorganic cation transport GO:0015672 172 0.011
negative regulation of neuron apoptotic process GO:0043524 45 0.011
single organism organelle organization GO:1902589 180 0.011
ovulation cycle GO:0042698 67 0.011
signal release GO:0023061 145 0.011
response to metal ion GO:0010038 253 0.011
extracellular matrix constituent secretion GO:0070278 4 0.011
organophosphate metabolic process GO:0019637 370 0.011
organic cyclic compound catabolic process GO:1901361 175 0.011
cellular nitrogen compound catabolic process GO:0044270 163 0.011
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 85 0.011
small molecule catabolic process GO:0044282 59 0.011
striated muscle tissue development GO:0014706 58 0.011
regulation of kinase activity GO:0043549 117 0.011
regulation of smooth muscle cell proliferation GO:0048660 75 0.011
response to hyperoxia GO:0055093 45 0.011
cellular divalent inorganic cation homeostasis GO:0072503 162 0.011
dna metabolic process GO:0006259 96 0.011
hormone metabolic process GO:0042445 69 0.011
regulation of immune system process GO:0002682 123 0.011
positive regulation of cellular component organization GO:0051130 200 0.011
positive regulation of protein kinase activity GO:0045860 73 0.011
anion transport GO:0006820 178 0.011
detection of chemical stimulus involved in sensory perception of bitter taste GO:0001580 4 0.010
synaptic transmission GO:0007268 235 0.010
reactive nitrogen species metabolic process GO:2001057 1 0.010
negative regulation of cellular protein metabolic process GO:0032269 106 0.010
cellular cation homeostasis GO:0030003 180 0.010
c21 steroid hormone metabolic process GO:0008207 14 0.010
cellular ion homeostasis GO:0006873 184 0.010
cytoskeleton organization GO:0007010 111 0.010
epithelial cell differentiation GO:0030855 71 0.010
positive regulation of cell death GO:0010942 184 0.010
neuronal action potential GO:0019228 35 0.010
regulation of cell activation GO:0050865 50 0.010
anatomical structure formation involved in morphogenesis GO:0048646 83 0.010

Nepn disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.017
nervous system disease DOID:863 0 0.017
integumentary system disease DOID:16 0 0.015