Rattus norvegicus

0 known processes

Plekhm2

pleckstrin homology domain containing, family M (with RUN domain) member 2

Plekhm2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
single organism catabolic process GO:0044712 283 0.063
positive regulation of nervous system development GO:0051962 178 0.057
brain development GO:0007420 247 0.050
regulation of phosphorus metabolic process GO:0051174 349 0.046
protein phosphorylation GO:0006468 345 0.046
regulation of cell differentiation GO:0045595 320 0.045
central nervous system development GO:0007417 311 0.044
catabolic process GO:0009056 351 0.043
regulation of phosphorylation GO:0042325 248 0.042
cell projection organization GO:0030030 302 0.042
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.040
cellular amino acid metabolic process GO:0006520 107 0.039
ion homeostasis GO:0050801 212 0.038
macromolecular complex subunit organization GO:0043933 339 0.037
head development GO:0060322 247 0.036
positive regulation of cell communication GO:0010647 271 0.036
multi organism reproductive process GO:0044703 262 0.035
cellular chemical homeostasis GO:0055082 247 0.033
cell cell signaling GO:0007267 335 0.033
single organism reproductive process GO:0044702 297 0.033
regulation of cell development GO:0060284 263 0.032
positive regulation of multicellular organismal process GO:0051240 387 0.032
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.032
reproductive process GO:0022414 372 0.031
regulation of protein metabolic process GO:0051246 289 0.030
response to hypoxia GO:0001666 231 0.030
positive regulation of cellular biosynthetic process GO:0031328 295 0.029
regulation of protein modification process GO:0031399 194 0.029
cellular response to oxygen containing compound GO:1901701 386 0.028
cellular amine metabolic process GO:0044106 38 0.028
rna metabolic process GO:0016070 406 0.028
positive regulation of neurogenesis GO:0050769 165 0.028
regulation of cell proliferation GO:0042127 359 0.028
regulation of signal transduction GO:0009966 318 0.028
positive regulation of phosphorylation GO:0042327 177 0.027
positive regulation of cellular component organization GO:0051130 200 0.027
regulation of protein phosphorylation GO:0001932 183 0.027
positive regulation of developmental process GO:0051094 283 0.027
cell morphogenesis involved in differentiation GO:0000904 119 0.027
nucleoside phosphate metabolic process GO:0006753 283 0.026
organophosphate metabolic process GO:0019637 370 0.026
rhythmic process GO:0048511 156 0.026
neuron projection development GO:0031175 273 0.025
response to growth factor GO:0070848 189 0.025
regulation of neurogenesis GO:0050767 247 0.025
positive regulation of cell differentiation GO:0045597 217 0.025
neuron differentiation GO:0030182 368 0.024
chemosensory behavior GO:0007635 2 0.024
transcription dna templated GO:0006351 377 0.024
regulation of neuron projection development GO:0010975 161 0.024
transmembrane transport GO:0055085 412 0.024
rna biosynthetic process GO:0032774 380 0.024
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.024
regulation of vesicle mediated transport GO:0060627 81 0.024
positive regulation of phosphorus metabolic process GO:0010562 262 0.023
regulation of cellular amino acid metabolic process GO:0006521 2 0.023
positive regulation of signaling GO:0023056 270 0.023
response to cytokine GO:0034097 215 0.023
regulation of transferase activity GO:0051338 123 0.023
positive regulation of cellular amine metabolic process GO:0033240 3 0.022
nucleic acid templated transcription GO:0097659 379 0.022
positive regulation of protein modification process GO:0031401 142 0.022
nucleotide metabolic process GO:0009117 279 0.022
purine ribonucleotide metabolic process GO:0009150 227 0.022
regulation of molecular function GO:0065009 398 0.022
positive regulation of biosynthetic process GO:0009891 319 0.022
divalent inorganic cation homeostasis GO:0072507 165 0.022
ribose phosphate metabolic process GO:0019693 235 0.022
positive regulation of protein metabolic process GO:0051247 178 0.021
multicellular organismal reproductive process GO:0048609 233 0.021
positive regulation of cell development GO:0010720 176 0.021
positive regulation of signal transduction GO:0009967 175 0.021
ribonucleotide metabolic process GO:0009259 231 0.021
secretion GO:0046903 307 0.021
tissue remodeling GO:0048771 40 0.021
positive regulation of molecular function GO:0044093 230 0.021
positive regulation of cellular protein metabolic process GO:0032270 167 0.021
regulation of secretion by cell GO:1903530 208 0.020
macromolecule localization GO:0033036 252 0.020
regulation of multicellular organismal development GO:2000026 376 0.020
regulation of transcription dna templated GO:0006355 374 0.020
purine containing compound metabolic process GO:0072521 253 0.020
cellular homeostasis GO:0019725 252 0.020
cellular calcium ion homeostasis GO:0006874 160 0.020
regulation of cellular amine metabolic process GO:0033238 8 0.020
cellular ion homeostasis GO:0006873 184 0.020
cellular divalent inorganic cation homeostasis GO:0072503 162 0.020
negative regulation of cellular metabolic process GO:0031324 281 0.019
secretion by cell GO:0032940 248 0.019
anterior posterior pattern specification GO:0009952 1 0.019
positive regulation of response to stimulus GO:0048584 285 0.019
regulation of mapk cascade GO:0043408 116 0.019
cellular metal ion homeostasis GO:0006875 172 0.019
response to heat GO:0009408 60 0.019
bmp signaling pathway GO:0030509 4 0.019
positive regulation of transport GO:0051050 245 0.019
neuron development GO:0048666 286 0.019
response to corticosteroid GO:0031960 235 0.019
negative regulation of metabolic process GO:0009892 331 0.019
microtubule organizing center organization GO:0031023 1 0.019
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.019
single organism carbohydrate metabolic process GO:0044723 118 0.019
regulation of nucleic acid templated transcription GO:1903506 380 0.019
heart morphogenesis GO:0003007 3 0.018
organic acid metabolic process GO:0006082 292 0.018
regulation of nervous system development GO:0051960 264 0.018
regulation of cellular localization GO:0060341 263 0.018
neuronal action potential GO:0019228 35 0.018
biological adhesion GO:0022610 110 0.018
organic substance catabolic process GO:1901575 316 0.018
positive regulation of rna biosynthetic process GO:1902680 197 0.018
divalent inorganic cation transport GO:0072511 134 0.018
axis specification GO:0009798 4 0.018
metal ion homeostasis GO:0055065 186 0.018
metal ion transport GO:0030001 289 0.018
response to extracellular stimulus GO:0009991 380 0.018
amine metabolic process GO:0009308 38 0.018
hair follicle development GO:0001942 2 0.018
regulation of cellular component organization GO:0051128 368 0.018
calcium ion homeostasis GO:0055074 162 0.017
anatomical structure morphogenesis GO:0009653 298 0.017
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.017
positive regulation of phosphate metabolic process GO:0045937 262 0.017
negative regulation of multicellular organismal process GO:0051241 203 0.017
carbohydrate derivative metabolic process GO:1901135 346 0.017
regulation of immune system process GO:0002682 123 0.017
response to inorganic substance GO:0010035 377 0.017
chemical homeostasis GO:0048878 292 0.017
regulation of cellular ketone metabolic process GO:0010565 27 0.017
female pregnancy GO:0007565 122 0.017
development of primary sexual characteristics GO:0045137 107 0.017
regulation of secretion GO:0051046 224 0.017
ribose phosphate biosynthetic process GO:0046390 87 0.017
regulation of phosphate metabolic process GO:0019220 349 0.017
proteolysis GO:0006508 175 0.017
protein oligomerization GO:0051259 191 0.017
multicellular organism reproduction GO:0032504 233 0.017
b cell mediated immunity GO:0019724 4 0.016
regulation of membrane potential GO:0042391 110 0.016
response to carbohydrate GO:0009743 183 0.016
intracellular signal transduction GO:0035556 314 0.016
maintenance of protein location in plasma membrane GO:0072660 1 0.016
carbohydrate catabolic process GO:0016052 40 0.016
oxoacid metabolic process GO:0043436 290 0.016
cellular component assembly GO:0022607 360 0.016
negative regulation of secretion by cell GO:1903531 72 0.016
oxidation reduction process GO:0055114 304 0.016
carboxylic acid metabolic process GO:0019752 289 0.016
positive regulation of protein phosphorylation GO:0001934 135 0.016
homeostatic process GO:0042592 331 0.015
circulatory system process GO:0003013 183 0.015
regulation of hydrolase activity GO:0051336 143 0.015
regulation of rna biosynthetic process GO:2001141 381 0.015
organelle organization GO:0006996 266 0.015
regulation of cellular protein metabolic process GO:0032268 267 0.015
cellular carbohydrate metabolic process GO:0044262 72 0.015
cell adhesion GO:0007155 110 0.015
response to ketone GO:1901654 182 0.015
response to hexose GO:0009746 144 0.015
carbohydrate metabolic process GO:0005975 130 0.014
regulation of purine nucleotide metabolic process GO:1900542 115 0.014
cellular response to nitrogen compound GO:1901699 210 0.014
regulation of cell projection organization GO:0031344 175 0.014
regulation of nucleotide metabolic process GO:0006140 117 0.014
peptidyl tyrosine modification GO:0018212 72 0.014
gastrulation GO:0007369 2 0.014
reproductive system development GO:0061458 128 0.014
nucleoside phosphate biosynthetic process GO:1901293 102 0.014
single organism intracellular transport GO:1902582 166 0.014
activation of protein kinase activity GO:0032147 47 0.014
response to oxygen levels GO:0070482 265 0.014
protein heterooligomerization GO:0051291 89 0.014
salivary gland development GO:0007431 3 0.014
neuron death GO:0070997 127 0.014
positive regulation of gene expression GO:0010628 244 0.014
positive regulation of cell proliferation GO:0008284 249 0.014
positive regulation of catalytic activity GO:0043085 184 0.014
positive regulation of neuron differentiation GO:0045666 126 0.014
positive regulation of rna metabolic process GO:0051254 203 0.014
regulation of homeostatic process GO:0032844 101 0.014
vesicle mediated transport GO:0016192 181 0.014
response to temperature stimulus GO:0009266 94 0.014
response to monosaccharide GO:0034284 159 0.014
lipid modification GO:0030258 52 0.014
gliogenesis GO:0042063 93 0.014
divalent metal ion transport GO:0070838 132 0.013
regulation of apoptotic process GO:0042981 335 0.013
cellular response to endogenous stimulus GO:0071495 377 0.013
positive regulation of transcription dna templated GO:0045893 197 0.013
embryonic pattern specification GO:0009880 1 0.013
response to decreased oxygen levels GO:0036293 237 0.013
positive regulation of neuron projection development GO:0010976 99 0.013
purine nucleoside metabolic process GO:0042278 169 0.013
response to oxidative stress GO:0006979 186 0.013
cellular response to hormone stimulus GO:0032870 247 0.013
regulation of neuron death GO:1901214 115 0.013
reproduction GO:0000003 245 0.013
nucleobase containing small molecule metabolic process GO:0055086 316 0.013
organ morphogenesis GO:0009887 75 0.013
sequestering of calcium ion GO:0051208 8 0.013
protein complex assembly GO:0006461 263 0.013
synaptic transmission GO:0007268 235 0.013
protein complex biogenesis GO:0070271 263 0.013
synaptic growth at neuromuscular junction GO:0051124 1 0.013
eye morphogenesis GO:0048592 4 0.013
carbohydrate derivative biosynthetic process GO:1901137 124 0.013
cellular ketone metabolic process GO:0042180 51 0.013
transmission of nerve impulse GO:0019226 42 0.013
positive regulation of programmed cell death GO:0043068 157 0.013
activation of cysteine type endopeptidase activity GO:0097202 4 0.013
positive regulation of mapk cascade GO:0043410 92 0.013
protein localization GO:0008104 191 0.013
nitrogen compound transport GO:0071705 229 0.013
positive regulation of kinase activity GO:0033674 77 0.013
negative regulation of cellular component organization GO:0051129 83 0.013
detection of chemical stimulus involved in sensory perception of bitter taste GO:0001580 4 0.013
regulation of system process GO:0044057 208 0.013
response to nutrient levels GO:0031667 370 0.013
positive regulation of apoptotic process GO:0043065 154 0.013
multi multicellular organism process GO:0044706 138 0.013
sensory perception GO:0007600 101 0.013
positive regulation of cytosolic calcium ion concentration GO:0007204 122 0.013
purine nucleotide metabolic process GO:0006163 229 0.013
negative regulation of cell communication GO:0010648 158 0.013
cytosolic calcium ion homeostasis GO:0051480 140 0.013
purine ribonucleotide biosynthetic process GO:0009152 81 0.013
developmental process involved in reproduction GO:0003006 159 0.012
regulation of protein transport GO:0051223 68 0.012
negative regulation of gene expression GO:0010629 199 0.012
cellular response to external stimulus GO:0071496 118 0.012
multicellular organismal signaling GO:0035637 44 0.012
regulation of kinase activity GO:0043549 117 0.012
cellular response to growth factor stimulus GO:0071363 162 0.012
cellular macromolecule localization GO:0070727 122 0.012
sensory perception of pain GO:0019233 73 0.012
regulation of cytokine production GO:0001817 56 0.012
signal transduction by phosphorylation GO:0023014 144 0.012
regulation of catalytic activity GO:0050790 304 0.012
gonad development GO:0008406 104 0.012
multicellular organism growth GO:0035264 1 0.012
regulation of rna metabolic process GO:0051252 391 0.012
phosphatidylinositol dephosphorylation GO:0046856 4 0.012
negative regulation of molecular function GO:0044092 133 0.012
heterocycle catabolic process GO:0046700 167 0.012
gamete generation GO:0007276 124 0.012
positive regulation of endothelial cell migration GO:0010595 4 0.012
hair cycle GO:0042633 3 0.012
neuron projection morphogenesis GO:0048812 122 0.012
carbohydrate derivative catabolic process GO:1901136 147 0.012
cell cell signaling involved in cell fate commitment GO:0045168 2 0.012
regulation of synaptic transmission GO:0050804 141 0.012
response to glucose GO:0009749 136 0.012
cellular cation homeostasis GO:0030003 180 0.012
hepaticobiliary system development GO:0061008 90 0.012
macromolecular complex assembly GO:0065003 273 0.012
cellular lipid metabolic process GO:0044255 208 0.012
ribonucleoside metabolic process GO:0009119 174 0.012
maintenance of location GO:0051235 17 0.012
negative regulation of catalytic activity GO:0043086 103 0.012
regulation of programmed cell death GO:0043067 341 0.012
establishment of tissue polarity GO:0007164 2 0.012
positive regulation of nucleic acid templated transcription GO:1903508 197 0.012
generation of precursor metabolites and energy GO:0006091 62 0.012
response to peptide GO:1901652 292 0.012
regulation of anatomical structure size GO:0090066 135 0.012
salivary gland morphogenesis GO:0007435 1 0.011
response to peptide hormone GO:0043434 278 0.011
intracellular transport GO:0046907 185 0.011
negative regulation of transport GO:0051051 136 0.011
action potential GO:0001508 54 0.011
immunoglobulin mediated immune response GO:0016064 4 0.011
nucleoside phosphate catabolic process GO:1901292 140 0.011
cell morphogenesis GO:0000902 142 0.011
negative regulation of signaling GO:0023057 157 0.011
regulation of bmp signaling pathway GO:0030510 2 0.011
purine ribonucleotide catabolic process GO:0009154 136 0.011
g protein coupled receptor signaling pathway GO:0007186 242 0.011
inflammatory response GO:0006954 150 0.011
regulation of protein kinase activity GO:0045859 105 0.011
positive regulation of protein kinase activity GO:0045860 73 0.011
cellular nitrogen compound catabolic process GO:0044270 163 0.011
cell junction organization GO:0034330 21 0.011
response to external biotic stimulus GO:0043207 221 0.011
ribonucleotide biosynthetic process GO:0009260 85 0.011
cyclic nucleotide metabolic process GO:0009187 80 0.011
gtp metabolic process GO:0046039 72 0.011
single organism carbohydrate catabolic process GO:0044724 40 0.011
cellular component biogenesis GO:0044085 368 0.011
regulation of ion transport GO:0043269 245 0.011
establishment of protein localization GO:0045184 141 0.011
positive regulation of lipid kinase activity GO:0090218 2 0.011
glial cell differentiation GO:0010001 65 0.011
regulation of endocytosis GO:0030100 42 0.011
glycosyl compound metabolic process GO:1901657 182 0.011
membrane organization GO:0061024 94 0.011
epithelium development GO:0060429 96 0.011
mesoderm development GO:0007498 2 0.010
sequestering of metal ion GO:0051238 9 0.010
forebrain development GO:0030900 98 0.010
regulation of map kinase activity GO:0043405 53 0.010
cellular response to ketone GO:1901655 51 0.010
ras protein signal transduction GO:0007265 29 0.010
anion transport GO:0006820 178 0.010
wound healing GO:0042060 122 0.010
neuromuscular process GO:0050905 2 0.010
regulation of gtpase activity GO:0043087 57 0.010
cation homeostasis GO:0055080 195 0.010
purine containing compound biosynthetic process GO:0072522 85 0.010
signal release GO:0023061 145 0.010
regulation of blood vessel size GO:0050880 89 0.010
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.010
cyclic nucleotide biosynthetic process GO:0009190 63 0.010
spermatogenesis GO:0007283 99 0.010
regulation of hormone levels GO:0010817 187 0.010
negative regulation of phosphate metabolic process GO:0045936 80 0.010
positive regulation of cell death GO:0010942 184 0.010
programmed cell death GO:0012501 392 0.010
negative regulation of secretion GO:0051048 82 0.010
cellular catabolic process GO:0044248 295 0.010

Plekhm2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.013
nervous system disease DOID:863 0 0.013