Rattus norvegicus

34 known processes

Mdk

midkine

Mdk biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cellular amino acid metabolic process GO:0006520 107 0.186
response to corticosteroid GO:0031960 235 0.141
positive regulation of response to stimulus GO:0048584 285 0.107
head development GO:0060322 247 0.091
regulation of rna metabolic process GO:0051252 391 0.086
multi organism reproductive process GO:0044703 262 0.086
reproductive process GO:0022414 372 0.075
brain development GO:0007420 247 0.075
organic acid metabolic process GO:0006082 292 0.075
programmed cell death GO:0012501 392 0.073
central nervous system development GO:0007417 311 0.072
neuron differentiation GO:0030182 368 0.067
regulation of cellular protein metabolic process GO:0032268 267 0.065
cellular component biogenesis GO:0044085 368 0.064
response to cytokine GO:0034097 215 0.063
aging GO:0007568 241 0.063
regulation of catalytic activity GO:0050790 304 0.062
regulation of signal transduction GO:0009966 318 0.059
negative regulation of cell death GO:0060548 229 0.056
single organism reproductive process GO:0044702 297 0.055
response to glucocorticoid GO:0051384 223 0.053
regulation of cellular amino acid metabolic process GO:0006521 2 0.053
amine metabolic process GO:0009308 38 0.051
negative regulation of metabolic process GO:0009892 331 0.050
carboxylic acid metabolic process GO:0019752 289 0.049
response to estrogen GO:0043627 232 0.047
oxoacid metabolic process GO:0043436 290 0.047
response to inorganic substance GO:0010035 377 0.046
positive regulation of signal transduction GO:0009967 175 0.046
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.045
response to hypoxia GO:0001666 231 0.045
protein complex biogenesis GO:0070271 263 0.044
cellular amide metabolic process GO:0043603 44 0.044
rhythmic process GO:0048511 156 0.044
response to molecule of bacterial origin GO:0002237 194 0.044
rna metabolic process GO:0016070 406 0.044
regulation of cellular amine metabolic process GO:0033238 8 0.044
regulation of protein metabolic process GO:0051246 289 0.044
response to metal ion GO:0010038 253 0.042
negative regulation of cellular metabolic process GO:0031324 281 0.041
regulation of phosphorylation GO:0042325 248 0.041
positive regulation of cell communication GO:0010647 271 0.040
response to oxygen levels GO:0070482 265 0.039
positive regulation of developmental process GO:0051094 283 0.039
macromolecular complex assembly GO:0065003 273 0.039
regulation of programmed cell death GO:0043067 341 0.039
cell projection organization GO:0030030 302 0.039
reproduction GO:0000003 245 0.039
regulation of molecular function GO:0065009 398 0.038
rna biosynthetic process GO:0032774 380 0.037
multicellular organism reproduction GO:0032504 233 0.037
cellular amine metabolic process GO:0044106 38 0.037
negative regulation of gene expression GO:0010629 199 0.037
positive regulation of cell proliferation GO:0008284 249 0.036
positive regulation of cellular amine metabolic process GO:0033240 3 0.036
response to amino acid GO:0043200 75 0.036
anatomical structure morphogenesis GO:0009653 298 0.035
negative regulation of macromolecule metabolic process GO:0010605 260 0.035
response to nutrient levels GO:0031667 370 0.035
response to extracellular stimulus GO:0009991 380 0.035
response to acid chemical GO:0001101 222 0.034
response to peptide hormone GO:0043434 278 0.034
protein complex assembly GO:0006461 263 0.034
transcription from rna polymerase ii promoter GO:0006366 252 0.033
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.033
positive regulation of signaling GO:0023056 270 0.033
cellular response to stress GO:0033554 269 0.033
response to organophosphorus GO:0046683 102 0.032
regulation of neuron differentiation GO:0045664 208 0.032
cellular response to lipid GO:0071396 201 0.032
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.031
protein oligomerization GO:0051259 191 0.031
regulation of transcription dna templated GO:0006355 374 0.031
eye morphogenesis GO:0048592 4 0.031
cellular ketone metabolic process GO:0042180 51 0.030
gland development GO:0048732 155 0.030
response to peptide GO:1901652 292 0.030
embryonic appendage morphogenesis GO:0035113 4 0.030
positive regulation of erk1 and erk2 cascade GO:0070374 29 0.030
cellular response to external stimulus GO:0071496 118 0.029
nucleic acid templated transcription GO:0097659 379 0.029
response to interleukin 1 GO:0070555 55 0.028
regulation of apoptotic process GO:0042981 335 0.028
apoptotic process GO:0006915 381 0.028
female pregnancy GO:0007565 122 0.028
regulation of rna biosynthetic process GO:2001141 381 0.028
regulation of cell differentiation GO:0045595 320 0.028
response to decreased oxygen levels GO:0036293 237 0.028
positive regulation of phosphorus metabolic process GO:0010562 262 0.027
transmembrane transport GO:0055085 412 0.027
negative regulation of programmed cell death GO:0043069 183 0.026
positive regulation of multicellular organismal process GO:0051240 387 0.026
regulation of multicellular organismal development GO:2000026 376 0.026
positive regulation of cellular protein metabolic process GO:0032270 167 0.026
cellular response to oxygen containing compound GO:1901701 386 0.026
anterior posterior pattern specification GO:0009952 1 0.026
negative regulation of rna metabolic process GO:0051253 123 0.026
response to transition metal nanoparticle GO:1990267 122 0.025
regulation of neurogenesis GO:0050767 247 0.025
negative regulation of neuron apoptotic process GO:0043524 45 0.025
cellular component assembly GO:0022607 360 0.025
negative regulation of apoptotic process GO:0043066 181 0.025
cellular response to organic cyclic compound GO:0071407 202 0.025
response to ketone GO:1901654 182 0.024
developmental process involved in reproduction GO:0003006 159 0.024
intracellular signal transduction GO:0035556 314 0.024
positive regulation of epithelial cell proliferation GO:0050679 32 0.024
g protein coupled receptor signaling pathway GO:0007186 242 0.024
multicellular organismal reproductive process GO:0048609 233 0.023
positive regulation of phosphate metabolic process GO:0045937 262 0.023
regulation of cellular ketone metabolic process GO:0010565 27 0.023
regulation of phosphate metabolic process GO:0019220 349 0.022
reproductive structure development GO:0048608 128 0.022
regulation of synaptic plasticity GO:0048167 70 0.022
positive regulation of protein metabolic process GO:0051247 178 0.021
positive regulation of cell differentiation GO:0045597 217 0.021
transcription dna templated GO:0006351 377 0.021
multi multicellular organism process GO:0044706 138 0.021
cytokine production GO:0001816 61 0.021
retina morphogenesis in camera type eye GO:0060042 1 0.021
gonad development GO:0008406 104 0.021
positive regulation of neuron differentiation GO:0045666 126 0.020
cellular modified amino acid metabolic process GO:0006575 61 0.020
positive regulation of protein phosphorylation GO:0001934 135 0.020
macromolecular complex subunit organization GO:0043933 339 0.020
cellular response to organonitrogen compound GO:0071417 197 0.020
wound healing GO:0042060 122 0.020
neuron projection development GO:0031175 273 0.020
metal ion homeostasis GO:0055065 186 0.020
response to wounding GO:0009611 254 0.020
epithelial cell proliferation GO:0050673 54 0.020
ovulation cycle GO:0042698 67 0.020
protein complex subunit organization GO:0071822 302 0.020
homeostatic process GO:0042592 331 0.019
development of primary sexual characteristics GO:0045137 107 0.019
negative regulation of signal transduction GO:0009968 83 0.019
immune system process GO:0002376 204 0.019
response to nutrient GO:0007584 248 0.019
positive regulation of nervous system development GO:0051962 178 0.019
cellular response to interleukin 1 GO:0071347 37 0.019
positive regulation of secretion by cell GO:1903532 128 0.019
neuron development GO:0048666 286 0.019
tube development GO:0035295 89 0.019
metal ion transport GO:0030001 289 0.018
response to radiation GO:0009314 137 0.018
negative regulation of nucleic acid templated transcription GO:1903507 117 0.018
cellular response to steroid hormone stimulus GO:0071383 93 0.018
sensory organ development GO:0007423 74 0.018
regulation of canonical wnt signaling pathway GO:0060828 4 0.018
male sex differentiation GO:0046661 64 0.018
regulation of anatomical structure morphogenesis GO:0022603 141 0.018
biological adhesion GO:0022610 110 0.018
regulation of nervous system development GO:0051960 264 0.017
neural crest cell differentiation GO:0014033 2 0.017
cell cell signaling GO:0007267 335 0.017
regulation of synaptic transmission GO:0050804 141 0.017
respiratory system development GO:0060541 45 0.017
response to ethanol GO:0045471 162 0.017
lung development GO:0030324 43 0.017
negative regulation of signaling GO:0023057 157 0.017
embryonic limb morphogenesis GO:0030326 4 0.017
peptidyl amino acid modification GO:0018193 126 0.017
reproductive system development GO:0061458 128 0.017
positive regulation of cell death GO:0010942 184 0.017
secretion GO:0046903 307 0.017
protein maturation GO:0051604 68 0.017
wnt signaling pathway planar cell polarity pathway GO:0060071 2 0.017
regeneration GO:0031099 163 0.017
cellular response to nitrogen compound GO:1901699 210 0.017
negative regulation of cell communication GO:0010648 158 0.016
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.016
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.016
negative regulation of protein maturation GO:1903318 47 0.016
regulation of cell development GO:0060284 263 0.016
camera type eye morphogenesis GO:0048593 2 0.016
peptide metabolic process GO:0006518 32 0.016
axis specification GO:0009798 4 0.016
positive regulation of biosynthetic process GO:0009891 319 0.016
proteolysis GO:0006508 175 0.015
response to estradiol GO:0032355 164 0.015
negative regulation of developmental process GO:0051093 125 0.015
endothelial cell proliferation GO:0001935 20 0.015
regulation of cell projection organization GO:0031344 175 0.015
localization of cell GO:0051674 202 0.015
mesoderm development GO:0007498 2 0.015
regulation of nucleic acid templated transcription GO:1903506 380 0.015
organ regeneration GO:0031100 101 0.015
negative regulation of response to stimulus GO:0048585 155 0.015
purine ribonucleotide metabolic process GO:0009150 227 0.015
growth GO:0040007 165 0.015
appendage morphogenesis GO:0035107 4 0.015
female gonad development GO:0008585 53 0.015
regulation of protein modification process GO:0031399 194 0.015
cell type specific apoptotic process GO:0097285 134 0.015
chemical homeostasis GO:0048878 292 0.015
nucleoside phosphate metabolic process GO:0006753 283 0.015
response to lipopolysaccharide GO:0032496 191 0.014
cellular response to growth factor stimulus GO:0071363 162 0.014
regulation of phosphorus metabolic process GO:0051174 349 0.014
regulation of establishment of planar polarity GO:0090175 2 0.014
positive regulation of gene expression GO:0010628 244 0.014
muscle structure development GO:0061061 87 0.014
cell migration GO:0016477 197 0.014
response to mechanical stimulus GO:0009612 134 0.014
locomotion GO:0040011 237 0.014
secretion by cell GO:0032940 248 0.014
small gtpase mediated signal transduction GO:0007264 36 0.014
cellular response to cytokine stimulus GO:0071345 127 0.014
positive regulation of mapk cascade GO:0043410 92 0.014
embryonic pattern specification GO:0009880 1 0.014
response to other organism GO:0051707 220 0.013
catabolic process GO:0009056 351 0.013
response to carbohydrate GO:0009743 183 0.013
negative regulation of catalytic activity GO:0043086 103 0.013
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.013
positive regulation of cell development GO:0010720 176 0.013
negative regulation of peptidase activity GO:0010466 38 0.013
positive regulation of phosphorylation GO:0042327 177 0.013
negative regulation of endopeptidase activity GO:0010951 36 0.013
renal system development GO:0072001 67 0.013
regulation of cellular localization GO:0060341 263 0.013
circulatory system development GO:0072359 134 0.013
regulation of protein maturation GO:1903317 50 0.013
nucleotide metabolic process GO:0009117 279 0.013
cellular response to metal ion GO:0071248 55 0.013
cellular response to endogenous stimulus GO:0071495 377 0.013
response to vitamin GO:0033273 131 0.012
establishment of tissue polarity GO:0007164 2 0.012
synaptic transmission GO:0007268 235 0.012
regulation of body fluid levels GO:0050878 90 0.012
hair cycle process GO:0022405 2 0.012
embryonic axis specification GO:0000578 1 0.012
hair follicle development GO:0001942 2 0.012
negative regulation of cell differentiation GO:0045596 99 0.012
positive regulation of intracellular signal transduction GO:1902533 138 0.012
regulation of peptidase activity GO:0052547 55 0.012
camera type eye development GO:0043010 48 0.012
negative regulation of biosynthetic process GO:0009890 168 0.012
regulation of bmp signaling pathway GO:0030510 2 0.012
ion transmembrane transport GO:0034220 365 0.012
regulation of locomotion GO:0040012 148 0.012
cellular component movement GO:0006928 248 0.012
negative regulation of osteoblast differentiation GO:0045668 2 0.012
prostate gland morphogenesis GO:0060512 2 0.012
endocrine system development GO:0035270 30 0.012
regulation of cell proliferation GO:0042127 359 0.012
cellular response to extracellular stimulus GO:0031668 73 0.012
regulation of secretion by cell GO:1903530 208 0.012
positive regulation of protein modification process GO:0031401 142 0.012
digestive system development GO:0055123 41 0.011
negative regulation of cellular biosynthetic process GO:0031327 161 0.011
protein heterooligomerization GO:0051291 89 0.011
response to reactive oxygen species GO:0000302 120 0.011
gastrulation GO:0007369 2 0.011
gamete generation GO:0007276 124 0.011
negative regulation of protein metabolic process GO:0051248 114 0.011
signal transduction by phosphorylation GO:0023014 144 0.011
response to glucose GO:0009749 136 0.011
negative regulation of cellular protein metabolic process GO:0032269 106 0.011
positive regulation of cellular component organization GO:0051130 200 0.011
kidney development GO:0001822 67 0.011
ras protein signal transduction GO:0007265 29 0.011
regulation of intracellular signal transduction GO:1902531 218 0.011
retina development in camera type eye GO:0060041 27 0.011
regulation of cell projection size GO:0032536 1 0.011
osteoblast differentiation GO:0001649 26 0.011
response to monosaccharide GO:0034284 159 0.011
single organism biosynthetic process GO:0044711 342 0.011
palate development GO:0060021 2 0.011
positive regulation of rna metabolic process GO:0051254 203 0.011
cardiovascular system development GO:0072358 134 0.011
cell adhesion GO:0007155 110 0.011
tube formation GO:0035148 3 0.011
intestinal absorption GO:0050892 3 0.011
cellular response to inorganic substance GO:0071241 65 0.011
defense response GO:0006952 194 0.011
positive regulation of transport GO:0051050 245 0.011
negative regulation of molecular function GO:0044092 133 0.011
response to growth factor GO:0070848 189 0.010
regulation of cellular component organization GO:0051128 368 0.010
regulation of protein phosphorylation GO:0001932 183 0.010
regulation of mapk cascade GO:0043408 116 0.010
limb morphogenesis GO:0035108 4 0.010
cell growth GO:0016049 104 0.010
organelle organization GO:0006996 266 0.010
glucose homeostasis GO:0042593 75 0.010
regulation of growth GO:0040008 105 0.010

Mdk disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of cellular proliferation DOID:14566 0 0.030
cancer DOID:162 0 0.013
disease of anatomical entity DOID:7 0 0.012
gastrointestinal system disease DOID:77 0 0.012
vascular disease DOID:178 0 0.012
cardiovascular system disease DOID:1287 0 0.012