Rattus norvegicus

25 known processes

C1qb

complement component 1, q subcomponent, B chain

C1qb biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
programmed cell death GO:0012501 392 0.639
negative regulation of immune system process GO:0002683 39 0.638
regulation of cell proliferation GO:0042127 359 0.274
response to metal ion GO:0010038 253 0.229
immune system process GO:0002376 204 0.214
leukocyte mediated immunity GO:0002443 28 0.205
immune effector process GO:0002252 53 0.198
regulation of myeloid cell differentiation GO:0045637 12 0.186
cellular response to oxygen containing compound GO:1901701 386 0.186
aging GO:0007568 241 0.170
response to extracellular stimulus GO:0009991 380 0.162
antigen processing and presentation of peptide antigen GO:0048002 2 0.147
cellular response to organic cyclic compound GO:0071407 202 0.135
defense response GO:0006952 194 0.116
negative regulation of multicellular organismal process GO:0051241 203 0.111
cellular response to endogenous stimulus GO:0071495 377 0.111
response to acid chemical GO:0001101 222 0.106
complement activation GO:0006956 11 0.106
response to corticosteroid GO:0031960 235 0.104
response to nutrient levels GO:0031667 370 0.101
response to glucocorticoid GO:0051384 223 0.093
regulation of cell differentiation GO:0045595 320 0.092
kidney development GO:0001822 67 0.090
response to external biotic stimulus GO:0043207 221 0.089
positive regulation of multicellular organismal process GO:0051240 387 0.086
regulation of immune system process GO:0002682 123 0.085
lipoxygenase pathway GO:0019372 6 0.082
response to axon injury GO:0048678 59 0.082
negative regulation of apoptotic process GO:0043066 181 0.080
tissue remodeling GO:0048771 40 0.077
response to retinoic acid GO:0032526 63 0.071
response to wounding GO:0009611 254 0.068
neurological system process GO:0050877 219 0.068
regulation of tolerance induction to nonself antigen GO:0002655 1 0.064
response to cytokine GO:0034097 215 0.063
antigen processing and presentation of peptide antigen via mhc class ii GO:0002495 1 0.063
negative regulation of myeloid cell differentiation GO:0045638 3 0.062
response to other organism GO:0051707 220 0.062
brain development GO:0007420 247 0.061
immune response GO:0006955 104 0.060
negative regulation of programmed cell death GO:0043069 183 0.060
immunoglobulin mediated immune response GO:0016064 4 0.060
cellular response to growth factor stimulus GO:0071363 162 0.059
regulation of multicellular organismal development GO:2000026 376 0.059
inflammatory cell apoptotic process GO:0006925 5 0.057
negative regulation of cell death GO:0060548 229 0.055
negative regulation of developmental process GO:0051093 125 0.054
head development GO:0060322 247 0.053
negative regulation of cell differentiation GO:0045596 99 0.051
myeloid cell apoptotic process GO:0033028 6 0.048
metanephros development GO:0001656 14 0.048
cellular response to stress GO:0033554 269 0.048
response to peptide GO:1901652 292 0.047
response to hexose GO:0009746 144 0.046
cellular response to lipid GO:0071396 201 0.045
central nervous system development GO:0007417 311 0.042
response to vitamin GO:0033273 131 0.041
regulation of cell activation GO:0050865 50 0.041
response to glucose GO:0009749 136 0.041
apoptotic process GO:0006915 381 0.041
cellular component assembly GO:0022607 360 0.041
antigen processing and presentation of peptide or polysaccharide antigen via mhc class ii GO:0002504 1 0.040
regulation of mononuclear cell proliferation GO:0032944 26 0.040
positive regulation of neurogenesis GO:0050769 165 0.040
homeostatic process GO:0042592 331 0.040
regulation of immune response GO:0050776 55 0.039
negative regulation of collagen metabolic process GO:0010713 4 0.036
positive regulation of developmental process GO:0051094 283 0.035
macromolecular complex assembly GO:0065003 273 0.033
reproductive process GO:0022414 372 0.033
negative regulation of gene expression GO:0010629 199 0.033
cellular response to external stimulus GO:0071496 118 0.031
response to camp GO:0051591 91 0.031
regulation of nervous system development GO:0051960 264 0.030
response to carbohydrate GO:0009743 183 0.029
negative regulation of innate immune response GO:0045824 4 0.028
response to inorganic substance GO:0010035 377 0.028
negative regulation of cell proliferation GO:0008285 119 0.028
positive regulation of cell differentiation GO:0045597 217 0.028
tissue development GO:0009888 252 0.027
neuron development GO:0048666 286 0.027
antigen processing and presentation of exogenous peptide antigen via mhc class ii GO:0019886 1 0.027
sex differentiation GO:0007548 113 0.026
regulation of t cell activation GO:0050863 23 0.026
antigen processing and presentation GO:0019882 2 0.026
regulation of neuron projection development GO:0010975 161 0.026
positive regulation of hydrolase activity GO:0051345 86 0.025
positive regulation of neuron projection development GO:0010976 99 0.025
regulation of catalytic activity GO:0050790 304 0.025
regulation of epithelial cell proliferation GO:0050678 49 0.024
response to growth factor GO:0070848 189 0.024
negative regulation of response to stimulus GO:0048585 155 0.024
negative regulation of neuron death GO:1901215 69 0.023
development of primary sexual characteristics GO:0045137 107 0.023
cellular response to molecule of bacterial origin GO:0071219 56 0.023
regulation of cellular component organization GO:0051128 368 0.023
monovalent inorganic cation transport GO:0015672 172 0.022
regulation of leukocyte proliferation GO:0070663 26 0.022
regulation of programmed cell death GO:0043067 341 0.022
positive regulation of immune system process GO:0002684 90 0.022
lymphocyte proliferation GO:0046651 29 0.022
regulation of neurogenesis GO:0050767 247 0.022
regulation of cell migration GO:0030334 128 0.021
protein complex biogenesis GO:0070271 263 0.021
fc epsilon receptor signaling pathway GO:0038095 1 0.021
humoral immune response GO:0006959 12 0.021
response to monosaccharide GO:0034284 159 0.021
reactive oxygen species metabolic process GO:0072593 37 0.020
positive regulation of cell projection organization GO:0031346 111 0.020
cellular response to alcohol GO:0097306 87 0.020
innate immune response GO:0045087 35 0.020
cellular catabolic process GO:0044248 295 0.020
positive regulation of neuron differentiation GO:0045666 126 0.020
regulation of cellular protein metabolic process GO:0032268 267 0.020
protein complex assembly GO:0006461 263 0.020
nucleobase containing small molecule metabolic process GO:0055086 316 0.020
cellular amine metabolic process GO:0044106 38 0.020
vesicle mediated transport GO:0016192 181 0.019
triglyceride homeostasis GO:0070328 2 0.019
cellular response to cytokine stimulus GO:0071345 127 0.019
reproduction GO:0000003 245 0.019
positive regulation of cell migration GO:0030335 96 0.019
intracellular signal transduction GO:0035556 314 0.019
neuron apoptotic process GO:0051402 88 0.019
response to nutrient GO:0007584 248 0.019
ovulation cycle GO:0042698 67 0.018
monocarboxylic acid metabolic process GO:0032787 152 0.018
cellular response to extracellular stimulus GO:0031668 73 0.018
response to interferon gamma GO:0034341 20 0.018
cell projection organization GO:0030030 302 0.018
chemical homeostasis GO:0048878 292 0.018
regulation of apoptotic process GO:0042981 335 0.018
multicellular organismal reproductive process GO:0048609 233 0.018
ribonucleotide metabolic process GO:0009259 231 0.017
glucose homeostasis GO:0042593 75 0.017
immune system development GO:0002520 41 0.017
negative regulation of lymphocyte activation GO:0051250 10 0.017
response to estradiol GO:0032355 164 0.017
regulation of lymphocyte activation GO:0051249 34 0.017
macromolecular complex subunit organization GO:0043933 339 0.017
response to ethanol GO:0045471 162 0.017
regulation of cell morphogenesis involved in differentiation GO:0010769 72 0.017
regulation of cell development GO:0060284 263 0.016
b cell mediated immunity GO:0019724 4 0.016
neuron projection development GO:0031175 273 0.016
positive regulation of cell development GO:0010720 176 0.016
regulation of neuron differentiation GO:0045664 208 0.016
negative regulation of fibrinolysis GO:0051918 2 0.016
sequestering of metal ion GO:0051238 9 0.016
regulation of cellular amine metabolic process GO:0033238 8 0.016
cellular chemical homeostasis GO:0055082 247 0.016
salivary gland development GO:0007431 3 0.016
smooth muscle cell migration GO:0014909 36 0.016
neutrophil apoptotic process GO:0001781 4 0.016
cellular response to inorganic substance GO:0071241 65 0.016
growth GO:0040007 165 0.016
positive regulation of nervous system development GO:0051962 178 0.015
oxoacid metabolic process GO:0043436 290 0.015
potassium ion transmembrane transport GO:0071805 71 0.015
positive regulation of cellular component movement GO:0051272 102 0.015
cell proliferation involved in heart morphogenesis GO:0061323 2 0.015
neuron differentiation GO:0030182 368 0.015
cell migration GO:0016477 197 0.015
carbohydrate homeostasis GO:0033500 75 0.014
inflammatory response GO:0006954 150 0.014
regulation of response to stress GO:0080134 126 0.014
regulation of cell projection organization GO:0031344 175 0.014
cation transport GO:0006812 382 0.014
carbohydrate derivative catabolic process GO:1901136 147 0.014
cation homeostasis GO:0055080 195 0.014
positive regulation of cellular component organization GO:0051130 200 0.014
negative regulation of humoral immune response GO:0002921 4 0.014
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 13 0.014
regeneration GO:0031099 163 0.014
intermediate filament organization GO:0045109 1 0.014
response to estrogen GO:0043627 232 0.014
regulation of lymphocyte proliferation GO:0050670 26 0.014
regulation of locomotion GO:0040012 148 0.014
reproductive structure development GO:0048608 128 0.013
neuron death GO:0070997 127 0.013
carboxylic acid metabolic process GO:0019752 289 0.013
negative regulation of response to external stimulus GO:0032102 37 0.013
regulation of heart morphogenesis GO:2000826 2 0.013
acylglycerol homeostasis GO:0055090 2 0.013
rhythmic process GO:0048511 156 0.013
single organism catabolic process GO:0044712 283 0.013
regulation of homeostatic process GO:0032844 101 0.013
sex determination GO:0007530 2 0.013
regulation of leukocyte mediated immunity GO:0002703 19 0.013
ribose phosphate metabolic process GO:0019693 235 0.013
behavior GO:0007610 205 0.013
negative regulation of defense response GO:0031348 19 0.013
regulation of phosphorylation GO:0042325 248 0.013
negative regulation of neutrophil apoptotic process GO:0033030 3 0.013
regulation of acute inflammatory response GO:0002673 23 0.013
single organism biosynthetic process GO:0044711 342 0.012
cellular response to biotic stimulus GO:0071216 59 0.012
negative regulation of protein metabolic process GO:0051248 114 0.012
humoral immune response mediated by circulating immunoglobulin GO:0002455 2 0.012
tolerance induction to nonself antigen GO:0002462 2 0.012
positive regulation of phosphorus metabolic process GO:0010562 262 0.012
response to organophosphorus GO:0046683 102 0.012
mapk cascade GO:0000165 140 0.012
cell growth GO:0016049 104 0.012
negative regulation of homeostatic process GO:0032845 47 0.012
fatty acid metabolic process GO:0006631 99 0.012
regulation of leukocyte chemotaxis GO:0002688 12 0.012
hepaticobiliary system development GO:0061008 90 0.012
renal system development GO:0072001 67 0.012
diet induced thermogenesis GO:0002024 1 0.012
cell activation GO:0001775 97 0.011
negative regulation of leukocyte apoptotic process GO:2000107 4 0.011
locomotion GO:0040011 237 0.011
positive regulation of interleukin 2 production GO:0032743 1 0.011
antigen processing and presentation of exogenous peptide antigen GO:0002478 1 0.011
mast cell mediated immunity GO:0002448 10 0.011
cellular response to monosaccharide stimulus GO:0071326 67 0.011
localization of cell GO:0051674 202 0.011
cardiovascular system development GO:0072358 134 0.011
regulation of cellular ketone metabolic process GO:0010565 27 0.011
positive regulation of reactive oxygen species metabolic process GO:2000379 16 0.011
cellular protein complex assembly GO:0043623 44 0.011
bone remodeling GO:0046849 23 0.011
cellular response to hormone stimulus GO:0032870 247 0.011
negative regulation of cellular protein metabolic process GO:0032269 106 0.011
multi multicellular organism process GO:0044706 138 0.011
adaptive immune response GO:0002250 14 0.011
lipid storage GO:0019915 1 0.011
regulation of system process GO:0044057 208 0.011
positive regulation of response to stimulus GO:0048584 285 0.010
cellular response to organonitrogen compound GO:0071417 197 0.010
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.010
dorsal ventral pattern formation GO:0009953 4 0.010
response to peptide hormone GO:0043434 278 0.010
hematopoietic progenitor cell differentiation GO:0002244 2 0.010
bone resorption GO:0045453 18 0.010
carbohydrate derivative metabolic process GO:1901135 346 0.010
single organism reproductive process GO:0044702 297 0.010
de novo protein folding GO:0006458 2 0.010
sexual reproduction GO:0019953 148 0.010
proteolysis GO:0006508 175 0.010
positive regulation of cell proliferation GO:0008284 249 0.010
cellular response to nutrient levels GO:0031669 60 0.010
nucleoside catabolic process GO:0009164 126 0.010
cellular response to hexose stimulus GO:0071331 65 0.010
cellular response to lipopolysaccharide GO:0071222 55 0.010

C1qb disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
artery disease DOID:0050828 0 0.170
cerebrovascular disease DOID:6713 0 0.170
disease of anatomical entity DOID:7 0 0.170
vascular disease DOID:178 0 0.170
cardiovascular system disease DOID:1287 0 0.170
skin disease DOID:37 0 0.086
integumentary system disease DOID:16 0 0.086
musculoskeletal system disease DOID:17 0 0.010
connective tissue disease DOID:65 0 0.010