Rattus norvegicus

0 known processes

Slc12a8

solute carrier family 12 (potassium/chloride transporters), member 8

(Aliases: Ccc9)

Slc12a8 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
cation transport GO:0006812 382 0.118
Rat
positive regulation of cellular biosynthetic process GO:0031328 295 0.067
positive regulation of cell proliferation GO:0008284 249 0.058
intracellular signal transduction GO:0035556 314 0.057
secretion by cell GO:0032940 248 0.055
regulation of programmed cell death GO:0043067 341 0.051
metal ion transport GO:0030001 289 0.045
Rat
positive regulation of multicellular organismal process GO:0051240 387 0.044
nitrogen compound transport GO:0071705 229 0.043
positive regulation of cell differentiation GO:0045597 217 0.042
homeostatic process GO:0042592 331 0.041
Rat
transmembrane transport GO:0055085 412 0.041
Rat
cellular response to oxygen containing compound GO:1901701 386 0.039
oxoacid metabolic process GO:0043436 290 0.037
response to inorganic substance GO:0010035 377 0.036
neuron differentiation GO:0030182 368 0.036
neuron projection development GO:0031175 273 0.036
rna biosynthetic process GO:0032774 380 0.036
response to extracellular stimulus GO:0009991 380 0.034
cellular ion homeostasis GO:0006873 184 0.034
regulation of transcription dna templated GO:0006355 374 0.033
rna metabolic process GO:0016070 406 0.033
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.033
secretion GO:0046903 307 0.033
neuron development GO:0048666 286 0.032
cellular amino acid metabolic process GO:0006520 107 0.032
organic acid metabolic process GO:0006082 292 0.032
regulation of nervous system development GO:0051960 264 0.032
regulation of apoptotic process GO:0042981 335 0.032
regulation of multicellular organismal development GO:2000026 376 0.031
response to carbohydrate GO:0009743 183 0.031
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.030
negative regulation of metabolic process GO:0009892 331 0.030
brain development GO:0007420 247 0.030
programmed cell death GO:0012501 392 0.030
cellular chemical homeostasis GO:0055082 247 0.030
calcium ion transport GO:0006816 131 0.030
chemical homeostasis GO:0048878 292 0.030
anatomical structure morphogenesis GO:0009653 298 0.030
positive regulation of developmental process GO:0051094 283 0.029
regulation of secretion GO:0051046 224 0.029
regulation of rna biosynthetic process GO:2001141 381 0.029
catabolic process GO:0009056 351 0.029
cellular homeostasis GO:0019725 252 0.028
Rat
tissue development GO:0009888 252 0.028
regulation of molecular function GO:0065009 398 0.028
cell projection organization GO:0030030 302 0.028
regulation of neuron differentiation GO:0045664 208 0.028
cellular ketone metabolic process GO:0042180 51 0.028
apoptotic process GO:0006915 381 0.028
positive regulation of cell development GO:0010720 176 0.027
response to nutrient levels GO:0031667 370 0.027
carboxylic acid metabolic process GO:0019752 289 0.027
organelle organization GO:0006996 266 0.026
regulation of cell proliferation GO:0042127 359 0.026
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.026
positive regulation of transcription dna templated GO:0045893 197 0.026
positive regulation of biosynthetic process GO:0009891 319 0.026
hormone secretion GO:0046879 115 0.025
cellular response to lipid GO:0071396 201 0.025
organic anion transport GO:0015711 132 0.025
single organism catabolic process GO:0044712 283 0.025
regulation of cell development GO:0060284 263 0.025
response to estrogen GO:0043627 232 0.025
regulation of cellular component organization GO:0051128 368 0.025
positive regulation of nucleic acid templated transcription GO:1903508 197 0.024
single organism reproductive process GO:0044702 297 0.024
positive regulation of cellular component organization GO:0051130 200 0.024
regulation of rna metabolic process GO:0051252 391 0.024
positive regulation of rna metabolic process GO:0051254 203 0.024
amine metabolic process GO:0009308 38 0.023
multi organism reproductive process GO:0044703 262 0.023
anion transport GO:0006820 178 0.023
Rat
protein phosphorylation GO:0006468 345 0.023
transcription dna templated GO:0006351 377 0.023
regulation of cellular protein metabolic process GO:0032268 267 0.023
regulation of cellular ketone metabolic process GO:0010565 27 0.023
organic acid transport GO:0015849 116 0.023
regulation of cell differentiation GO:0045595 320 0.023
response to monosaccharide GO:0034284 159 0.023
negative regulation of cell communication GO:0010648 158 0.022
positive regulation of cell communication GO:0010647 271 0.022
positive regulation of neurogenesis GO:0050769 165 0.022
positive regulation of nervous system development GO:0051962 178 0.022
response to metal ion GO:0010038 253 0.022
response to growth factor GO:0070848 189 0.022
positive regulation of rna biosynthetic process GO:1902680 197 0.021
cellular amine metabolic process GO:0044106 38 0.021
negative regulation of gene expression GO:0010629 199 0.021
positive regulation of gene expression GO:0010628 244 0.021
positive regulation of phosphorylation GO:0042327 177 0.021
cellular component biogenesis GO:0044085 368 0.020
regulation of nucleic acid templated transcription GO:1903506 380 0.020
regulation of protein metabolic process GO:0051246 289 0.020
tongue morphogenesis GO:0043587 3 0.020
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.020
regulation of cellular amino acid metabolic process GO:0006521 2 0.020
transcription from rna polymerase ii promoter GO:0006366 252 0.020
macromolecular complex subunit organization GO:0043933 339 0.020
multicellular organismal reproductive process GO:0048609 233 0.020
organic substance catabolic process GO:1901575 316 0.019
response to peptide hormone GO:0043434 278 0.019
cellular component movement GO:0006928 248 0.019
negative regulation of programmed cell death GO:0043069 183 0.018
response to hexose GO:0009746 144 0.018
response to radiation GO:0009314 137 0.018
regulation of anatomical structure morphogenesis GO:0022603 141 0.018
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.018
positive regulation of neuron differentiation GO:0045666 126 0.018
reproductive process GO:0022414 372 0.018
head development GO:0060322 247 0.018
cellular component assembly GO:0022607 360 0.018
positive regulation of cell projection organization GO:0031346 111 0.018
regulation of catalytic activity GO:0050790 304 0.017
synaptic transmission GO:0007268 235 0.017
cellular catabolic process GO:0044248 295 0.017
ion homeostasis GO:0050801 212 0.017
nucleic acid templated transcription GO:0097659 379 0.017
response to acid chemical GO:0001101 222 0.017
macromolecule localization GO:0033036 252 0.017
Rat
regulation of phosphorylation GO:0042325 248 0.017
inorganic ion transmembrane transport GO:0098660 229 0.017
Rat
regulation of neurogenesis GO:0050767 247 0.017
glycosyl compound metabolic process GO:1901657 182 0.017
negative regulation of macromolecule metabolic process GO:0010605 260 0.017
signal transduction by phosphorylation GO:0023014 144 0.017
organic hydroxy compound metabolic process GO:1901615 115 0.016
regeneration GO:0031099 163 0.016
central nervous system development GO:0007417 311 0.016
protein complex subunit organization GO:0071822 302 0.016
regulation of secretion by cell GO:1903530 208 0.016
reproduction GO:0000003 245 0.016
positive regulation of response to stimulus GO:0048584 285 0.016
spermatogenesis GO:0007283 99 0.016
protein localization GO:0008104 191 0.016
Rat
regulation of protein phosphorylation GO:0001932 183 0.016
negative regulation of nucleic acid templated transcription GO:1903507 117 0.016
aging GO:0007568 241 0.016
Rat
regulation of hormone secretion GO:0046883 106 0.015
response to nutrient GO:0007584 248 0.015
positive regulation of molecular function GO:0044093 230 0.015
macromolecular complex assembly GO:0065003 273 0.015
response to glucose GO:0009749 136 0.015
regulation of cell motility GO:2000145 131 0.015
negative regulation of cellular metabolic process GO:0031324 281 0.015
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.015
regulation of signal transduction GO:0009966 318 0.015
cellular response to organic cyclic compound GO:0071407 202 0.014
epithelial cell differentiation GO:0030855 71 0.014
cellular response to growth factor stimulus GO:0071363 162 0.014
positive regulation of cell death GO:0010942 184 0.014
cell cell signaling GO:0007267 335 0.014
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.014
regulation of mapk cascade GO:0043408 116 0.014
regulation of phosphorus metabolic process GO:0051174 349 0.014
positive regulation of cellular amine metabolic process GO:0033240 3 0.014
multicellular organism reproduction GO:0032504 233 0.014
regulation of cell projection organization GO:0031344 175 0.014
response to oxidative stress GO:0006979 186 0.014
cellular divalent inorganic cation homeostasis GO:0072503 162 0.014
aromatic compound catabolic process GO:0019439 168 0.014
regulation of neuron projection development GO:0010975 161 0.014
amide transport GO:0042886 105 0.014
nucleobase containing compound catabolic process GO:0034655 152 0.014
response to peptide GO:1901652 292 0.014
regulation of membrane potential GO:0042391 110 0.014
lipid transport GO:0006869 61 0.014
response to wounding GO:0009611 254 0.014
cellular cation homeostasis GO:0030003 180 0.013
regulation of phosphate metabolic process GO:0019220 349 0.013
organophosphate metabolic process GO:0019637 370 0.013
cation transmembrane transport GO:0098655 263 0.013
Rat
positive regulation of programmed cell death GO:0043068 157 0.013
calcium ion homeostasis GO:0055074 162 0.013
carbohydrate homeostasis GO:0033500 75 0.013
positive regulation of transport GO:0051050 245 0.013
regulation of ion transmembrane transport GO:0034765 121 0.013
protein complex assembly GO:0006461 263 0.013
negative regulation of cell death GO:0060548 229 0.013
protein complex biogenesis GO:0070271 263 0.013
regulation of intracellular signal transduction GO:1902531 218 0.013
sexual reproduction GO:0019953 148 0.013
cellular calcium ion homeostasis GO:0006874 160 0.013
peptide secretion GO:0002790 86 0.013
positive regulation of protein metabolic process GO:0051247 178 0.012
reproductive system development GO:0061458 128 0.012
cell motility GO:0048870 202 0.012
ras protein signal transduction GO:0007265 29 0.012
hematopoietic progenitor cell differentiation GO:0002244 2 0.012
small gtpase mediated signal transduction GO:0007264 36 0.012
positive regulation of neuron projection development GO:0010976 99 0.012
cellular response to stress GO:0033554 269 0.012
positive regulation of signaling GO:0023056 270 0.012
glucose homeostasis GO:0042593 75 0.012
response to oxygen levels GO:0070482 265 0.012
peptide transport GO:0015833 97 0.012
alcohol metabolic process GO:0006066 77 0.012
nucleotide catabolic process GO:0009166 139 0.012
locomotion GO:0040011 237 0.012
metal ion homeostasis GO:0055065 186 0.012
divalent inorganic cation transport GO:0072511 134 0.012
single organism organelle organization GO:1902589 180 0.012
regulation of cellular localization GO:0060341 263 0.012
alpha amino acid metabolic process GO:1901605 71 0.012
positive regulation of secretion by cell GO:1903532 128 0.012
signal release GO:0023061 145 0.012
ion transmembrane transport GO:0034220 365 0.012
Rat
cellular nitrogen compound catabolic process GO:0044270 163 0.012
nucleobase containing small molecule metabolic process GO:0055086 316 0.011
female pregnancy GO:0007565 122 0.011
male gamete generation GO:0048232 99 0.011
positive regulation of mapk cascade GO:0043410 92 0.011
positive regulation of apoptotic process GO:0043065 154 0.011
chromosome segregation GO:0007059 2 0.011
circulatory system development GO:0072359 134 0.011
mapk cascade GO:0000165 140 0.011
positive regulation of phosphorus metabolic process GO:0010562 262 0.011
positive regulation of protein modification process GO:0031401 142 0.011
sensory organ development GO:0007423 74 0.011
sex differentiation GO:0007548 113 0.011
negative regulation of signaling GO:0023057 157 0.011
reproductive structure development GO:0048608 128 0.011
lipid localization GO:0010876 62 0.011
cellular response to alcohol GO:0097306 87 0.011
eye morphogenesis GO:0048592 4 0.011
regulation of cellular component biogenesis GO:0044087 86 0.011
negative regulation of apoptotic process GO:0043066 181 0.011
regulation of hormone levels GO:0010817 187 0.011
nucleotide metabolic process GO:0009117 279 0.011
urogenital system development GO:0001655 78 0.011
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.011
carboxylic acid transport GO:0046942 115 0.011
inorganic cation transmembrane transport GO:0098662 202 0.011
Rat
gamete generation GO:0007276 124 0.011
calcium ion transmembrane transport GO:0070588 70 0.011
lipid metabolic process GO:0006629 283 0.011
Rat
ribose phosphate metabolic process GO:0019693 235 0.011
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.011
regulation of proteasomal protein catabolic process GO:0061136 4 0.010
heterocycle catabolic process GO:0046700 167 0.010
divalent metal ion transport GO:0070838 132 0.010
positive regulation of secretion GO:0051047 140 0.010
organic cyclic compound catabolic process GO:1901361 175 0.010
regulation of cellular amine metabolic process GO:0033238 8 0.010
sensory perception GO:0007600 101 0.010
regulation of organelle organization GO:0033043 80 0.010
regulation of locomotion GO:0040012 148 0.010
purine containing compound metabolic process GO:0072521 253 0.010
carbohydrate derivative metabolic process GO:1901135 346 0.010
developmental process involved in reproduction GO:0003006 159 0.010
dendrite development GO:0016358 72 0.010
positive regulation of cellular component biogenesis GO:0044089 55 0.010
oxidation reduction process GO:0055114 304 0.010
positive regulation of cellular protein metabolic process GO:0032270 167 0.010
forebrain development GO:0030900 98 0.010

Slc12a8 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.038
nervous system disease DOID:863 0 0.038
sensory system disease DOID:0050155 0 0.022
disease of metabolism DOID:0014667 0 0.015
central nervous system disease DOID:331 0 0.011
inherited metabolic disorder DOID:655 0 0.011