Rattus norvegicus

0 known processes

Lgmn

legumain

(Aliases: Prsc1,MGC105274)

Lgmn biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
oxoacid metabolic process GO:0043436 290 0.149
organic acid metabolic process GO:0006082 292 0.130
growth GO:0040007 165 0.117
programmed cell death GO:0012501 392 0.114
response to nutrient levels GO:0031667 370 0.105
carboxylic acid metabolic process GO:0019752 289 0.101
cellular response to endogenous stimulus GO:0071495 377 0.100
response to estradiol GO:0032355 164 0.092
response to glucocorticoid GO:0051384 223 0.088
reproductive process GO:0022414 372 0.079
response to peptide hormone GO:0043434 278 0.076
regulation of system process GO:0044057 208 0.073
regulation of programmed cell death GO:0043067 341 0.071
response to estrogen GO:0043627 232 0.070
response to extracellular stimulus GO:0009991 380 0.070
regulation of cellular component organization GO:0051128 368 0.068
response to peptide GO:1901652 292 0.064
response to corticosteroid GO:0031960 235 0.064
response to biotic stimulus GO:0009607 226 0.061
cellular response to hormone stimulus GO:0032870 247 0.060
cell projection organization GO:0030030 302 0.060
response to monosaccharide GO:0034284 159 0.058
multicellular organism reproduction GO:0032504 233 0.058
response to wounding GO:0009611 254 0.057
positive regulation of cell proliferation GO:0008284 249 0.056
response to ethanol GO:0045471 162 0.056
cellular amino acid metabolic process GO:0006520 107 0.054
tissue development GO:0009888 252 0.054
cation transport GO:0006812 382 0.053
regulation of neuron differentiation GO:0045664 208 0.052
regulation of leukocyte activation GO:0002694 45 0.051
response to external biotic stimulus GO:0043207 221 0.051
cellular response to organic cyclic compound GO:0071407 202 0.050
amine metabolic process GO:0009308 38 0.050
lymphocyte activation GO:0046649 43 0.050
vesicle mediated transport GO:0016192 181 0.050
multi organism reproductive process GO:0044703 262 0.049
cellular response to oxygen containing compound GO:1901701 386 0.047
wound healing GO:0042060 122 0.046
organic substance catabolic process GO:1901575 316 0.046
regulation of cellular ketone metabolic process GO:0010565 27 0.046
regulation of vesicle mediated transport GO:0060627 81 0.045
response to carbohydrate GO:0009743 183 0.045
positive regulation of transport GO:0051050 245 0.045
single organism biosynthetic process GO:0044711 342 0.045
organic acid biosynthetic process GO:0016053 83 0.045
regulation of locomotion GO:0040012 148 0.045
cellular response to nitrogen compound GO:1901699 210 0.045
anatomical structure morphogenesis GO:0009653 298 0.045
response to inorganic substance GO:0010035 377 0.044
reproductive structure development GO:0048608 128 0.044
single organism reproductive process GO:0044702 297 0.044
reproduction GO:0000003 245 0.043
regulation of cell proliferation GO:0042127 359 0.043
regulation of cell differentiation GO:0045595 320 0.043
regulation of cellular component movement GO:0051270 150 0.042
small molecule biosynthetic process GO:0044283 124 0.041
positive regulation of multicellular organismal process GO:0051240 387 0.040
anion transport GO:0006820 178 0.040
regulation of cellular amino acid metabolic process GO:0006521 2 0.040
response to oxygen levels GO:0070482 265 0.040
cell activation GO:0001775 97 0.039
organic acid transport GO:0015849 116 0.039
nucleic acid templated transcription GO:0097659 379 0.038
positive regulation of response to stimulus GO:0048584 285 0.037
urogenital system development GO:0001655 78 0.037
apoptotic process GO:0006915 381 0.037
response to other organism GO:0051707 220 0.037
regulation of transcription dna templated GO:0006355 374 0.037
response to hexose GO:0009746 144 0.037
developmental process involved in reproduction GO:0003006 159 0.037
cellular amine metabolic process GO:0044106 38 0.037
regulation of secretion GO:0051046 224 0.037
organic anion transport GO:0015711 132 0.036
kidney development GO:0001822 67 0.036
cellular ketone metabolic process GO:0042180 51 0.036
regulation of cellular localization GO:0060341 263 0.036
response to acid chemical GO:0001101 222 0.036
secretion GO:0046903 307 0.036
catabolic process GO:0009056 351 0.036
synaptic transmission GO:0007268 235 0.035
cellular response to external stimulus GO:0071496 118 0.035
biological adhesion GO:0022610 110 0.035
homeostatic process GO:0042592 331 0.035
single organism catabolic process GO:0044712 283 0.035
regulation of cell motility GO:2000145 131 0.034
aging GO:0007568 241 0.034
regulation of nucleic acid templated transcription GO:1903506 380 0.034
response to bacterium GO:0009617 200 0.034
nitrogen compound transport GO:0071705 229 0.033
regulation of cell development GO:0060284 263 0.033
negative regulation of cell death GO:0060548 229 0.033
regulation of nervous system development GO:0051960 264 0.033
regulation of multicellular organismal development GO:2000026 376 0.033
regulation of secretion by cell GO:1903530 208 0.033
multicellular organismal reproductive process GO:0048609 233 0.033
regulation of cellular protein metabolic process GO:0032268 267 0.032
response to glucose GO:0009749 136 0.032
regulation of apoptotic process GO:0042981 335 0.032
blood circulation GO:0008015 183 0.032
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.031
regulation of ion transport GO:0043269 245 0.031
secretion by cell GO:0032940 248 0.031
cellular response to stress GO:0033554 269 0.031
reproductive system development GO:0061458 128 0.031
response to cytokine GO:0034097 215 0.031
metal ion transport GO:0030001 289 0.030
response to molecule of bacterial origin GO:0002237 194 0.030
positive regulation of biosynthetic process GO:0009891 319 0.030
carboxylic acid biosynthetic process GO:0046394 83 0.030
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.030
neuron differentiation GO:0030182 368 0.030
cell growth GO:0016049 104 0.030
locomotion GO:0040011 237 0.029
sexual reproduction GO:0019953 148 0.029
positive regulation of cell motility GO:2000147 97 0.029
developmental growth GO:0048589 100 0.029
regulation of neurogenesis GO:0050767 247 0.029
cellular response to glucocorticoid stimulus GO:0071385 68 0.029
single organism carbohydrate catabolic process GO:0044724 40 0.029
regulation of protein modification process GO:0031399 194 0.029
response to mechanical stimulus GO:0009612 134 0.028
intracellular signal transduction GO:0035556 314 0.028
regulation of rna metabolic process GO:0051252 391 0.028
regulation of cell migration GO:0030334 128 0.028
cellular lipid metabolic process GO:0044255 208 0.028
positive regulation of cellular component movement GO:0051272 102 0.028
regulation of signal transduction GO:0009966 318 0.028
protein phosphorylation GO:0006468 345 0.027
transcription from rna polymerase ii promoter GO:0006366 252 0.027
transcription dna templated GO:0006351 377 0.027
cellular chemical homeostasis GO:0055082 247 0.027
response to oxidative stress GO:0006979 186 0.027
negative regulation of cellular biosynthetic process GO:0031327 161 0.027
neuron projection development GO:0031175 273 0.027
negative regulation of metabolic process GO:0009892 331 0.027
regulation of hormone levels GO:0010817 187 0.027
cellular response to mechanical stimulus GO:0071260 48 0.027
immunoglobulin mediated immune response GO:0016064 4 0.026
positive regulation of nervous system development GO:0051962 178 0.026
leukocyte activation GO:0045321 76 0.026
cell type specific apoptotic process GO:0097285 134 0.026
monocarboxylic acid metabolic process GO:0032787 152 0.026
cellular catabolic process GO:0044248 295 0.026
regulation of cellular amine metabolic process GO:0033238 8 0.026
carbohydrate derivative metabolic process GO:1901135 346 0.026
positive regulation of cell differentiation GO:0045597 217 0.025
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.025
b cell mediated immunity GO:0019724 4 0.025
epithelium development GO:0060429 96 0.025
organic hydroxy compound metabolic process GO:1901615 115 0.025
negative regulation of multicellular organismal process GO:0051241 203 0.025
gamete generation GO:0007276 124 0.024
positive regulation of cell communication GO:0010647 271 0.024
organophosphate metabolic process GO:0019637 370 0.024
carboxylic acid transport GO:0046942 115 0.024
regulation of protein metabolic process GO:0051246 289 0.024
response to lipopolysaccharide GO:0032496 191 0.024
intracellular transport GO:0046907 185 0.024
response to hypoxia GO:0001666 231 0.024
regulation of catalytic activity GO:0050790 304 0.024
cellular response to corticosteroid stimulus GO:0071384 69 0.024
rna biosynthetic process GO:0032774 380 0.024
regulation of cell activation GO:0050865 50 0.023
mononuclear cell proliferation GO:0032943 29 0.023
regulation of metal ion transport GO:0010959 118 0.023
single organism carbohydrate metabolic process GO:0044723 118 0.023
female pregnancy GO:0007565 122 0.023
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.023
response to nutrient GO:0007584 248 0.023
central nervous system development GO:0007417 311 0.023
proteolysis GO:0006508 175 0.023
cell morphogenesis GO:0000902 142 0.023
positive regulation of cellular biosynthetic process GO:0031328 295 0.023
signal release GO:0023061 145 0.023
regulation of immunoglobulin production GO:0002637 4 0.023
cell cell signaling GO:0007267 335 0.022
regulation of growth GO:0040008 105 0.022
multicellular organism growth GO:0035264 1 0.022
regulation of protein phosphorylation GO:0001932 183 0.022
macromolecule localization GO:0033036 252 0.022
regulation of immune system process GO:0002682 123 0.022
cellular component morphogenesis GO:0032989 155 0.022
negative regulation of macromolecule metabolic process GO:0010605 260 0.022
positive regulation of signaling GO:0023056 270 0.022
negative regulation of programmed cell death GO:0043069 183 0.022
cellular response to organonitrogen compound GO:0071417 197 0.022
negative regulation of cellular metabolic process GO:0031324 281 0.021
negative regulation of apoptotic process GO:0043066 181 0.021
response to growth factor GO:0070848 189 0.021
hormone transport GO:0009914 121 0.021
hematopoietic progenitor cell differentiation GO:0002244 2 0.021
regulation of phosphorylation GO:0042325 248 0.021
regulation of cell growth GO:0001558 85 0.021
lipid metabolic process GO:0006629 283 0.021
positive regulation of cellular component organization GO:0051130 200 0.021
protein oligomerization GO:0051259 191 0.021
carbohydrate metabolic process GO:0005975 130 0.021
negative regulation of biosynthetic process GO:0009890 168 0.021
transmembrane transport GO:0055085 412 0.021
positive regulation of cellular amine metabolic process GO:0033240 3 0.021
lymphocyte proliferation GO:0046651 29 0.020
single organism intracellular transport GO:1902582 166 0.020
muscle cell proliferation GO:0033002 84 0.020
positive regulation of protein modification process GO:0031401 142 0.020
reactive oxygen species metabolic process GO:0072593 37 0.020
regulation of response to stress GO:0080134 126 0.019
regulation of neuron projection development GO:0010975 161 0.019
ion transmembrane transport GO:0034220 365 0.019
cell migration GO:0016477 197 0.019
cellular component biogenesis GO:0044085 368 0.019
regulation of rna biosynthetic process GO:2001141 381 0.019
cellular response to growth factor stimulus GO:0071363 162 0.019
circulatory system process GO:0003013 183 0.019
oxidation reduction process GO:0055114 304 0.019
neuron death GO:0070997 127 0.019
rna metabolic process GO:0016070 406 0.019
monovalent inorganic cation transport GO:0015672 172 0.019
interleukin 12 production GO:0032615 3 0.019
negative regulation of nucleic acid templated transcription GO:1903507 117 0.019
chemical homeostasis GO:0048878 292 0.019
negative regulation of gene expression GO:0010629 199 0.018
regulation of cell projection organization GO:0031344 175 0.018
cellular component assembly GO:0022607 360 0.018
behavior GO:0007610 205 0.018
multi multicellular organism process GO:0044706 138 0.018
organonitrogen compound biosynthetic process GO:1901566 167 0.018
signal transduction by phosphorylation GO:0023014 144 0.018
positive regulation of developmental process GO:0051094 283 0.018
regulation of blood pressure GO:0008217 83 0.018
response to reactive oxygen species GO:0000302 120 0.018
macromolecular complex assembly GO:0065003 273 0.018
response to organophosphorus GO:0046683 102 0.018
negative regulation of signaling GO:0023057 157 0.018
brain development GO:0007420 247 0.018
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.018
positive regulation of phosphorylation GO:0042327 177 0.018
positive regulation of molecular function GO:0044093 230 0.018
localization of cell GO:0051674 202 0.018
cellular response to reactive oxygen species GO:0034614 55 0.017
negative regulation of cell communication GO:0010648 158 0.017
cellular response to peptide GO:1901653 133 0.017
lipid biosynthetic process GO:0008610 128 0.017
defense response GO:0006952 194 0.017
cell adhesion GO:0007155 110 0.017
positive regulation of nucleic acid templated transcription GO:1903508 197 0.017
cytokine production GO:0001816 61 0.017
fatty acid metabolic process GO:0006631 99 0.017
positive regulation of protein metabolic process GO:0051247 178 0.017
regulation of anatomical structure size GO:0090066 135 0.017
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 85 0.017
hepaticobiliary system development GO:0061008 90 0.017
negative regulation of molecular function GO:0044092 133 0.017
dna metabolic process GO:0006259 96 0.017
organ morphogenesis GO:0009887 75 0.017
positive regulation of signal transduction GO:0009967 175 0.017
protein localization GO:0008104 191 0.016
regulation of cell adhesion GO:0030155 52 0.016
immune system process GO:0002376 204 0.016
regulation of anatomical structure morphogenesis GO:0022603 141 0.016
fatty acid biosynthetic process GO:0006633 33 0.016
leukocyte proliferation GO:0070661 29 0.016
protein complex biogenesis GO:0070271 263 0.016
regulation of phosphate metabolic process GO:0019220 349 0.016
positive regulation of neuron differentiation GO:0045666 126 0.016
protein complex assembly GO:0006461 263 0.016
spermatogenesis GO:0007283 99 0.016
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.016
response to decreased oxygen levels GO:0036293 237 0.016
cellular modified amino acid metabolic process GO:0006575 61 0.016
regulation of neuron death GO:1901214 115 0.016
negative regulation of cell proliferation GO:0008285 119 0.016
positive regulation of rna metabolic process GO:0051254 203 0.016
epithelial cell differentiation GO:0030855 71 0.016
inflammatory response GO:0006954 150 0.015
muscle system process GO:0003012 115 0.015
cellular response to abiotic stimulus GO:0071214 85 0.015
multicellular organismal homeostasis GO:0048871 49 0.015
salivary gland development GO:0007431 3 0.015
cellular response to steroid hormone stimulus GO:0071383 93 0.015
regulation of response to external stimulus GO:0032101 106 0.015
amino acid transport GO:0006865 70 0.015
positive regulation of cell development GO:0010720 176 0.015
cell projection morphogenesis GO:0048858 123 0.015
cellular homeostasis GO:0019725 252 0.015
autophagic cell death GO:0048102 4 0.015
regeneration GO:0031099 163 0.015
smooth muscle cell proliferation GO:0048659 77 0.015
positive regulation of secretion GO:0051047 140 0.015
nucleotide metabolic process GO:0009117 279 0.015
positive regulation of gene expression GO:0010628 244 0.015
negative regulation of transport GO:0051051 136 0.015
response to hydrogen peroxide GO:0042542 89 0.015
positive regulation of endothelial cell migration GO:0010595 4 0.015
regulation of cytokine production GO:0001817 56 0.015
sex differentiation GO:0007548 113 0.015
membrane organization GO:0061024 94 0.015
motor neuron axon guidance GO:0008045 1 0.015
renal system development GO:0072001 67 0.014
positive regulation of cellular protein metabolic process GO:0032270 167 0.014
positive regulation of phosphorus metabolic process GO:0010562 262 0.014
positive regulation of smooth muscle cell proliferation GO:0048661 51 0.014
cell substrate adhesion GO:0031589 29 0.014
regulation of organelle organization GO:0033043 80 0.014
positive regulation of cell migration GO:0030335 96 0.014
head development GO:0060322 247 0.014
gonad development GO:0008406 104 0.014
negative regulation of secretion by cell GO:1903531 72 0.014
response to insulin GO:0032868 133 0.014
immune response regulating signaling pathway GO:0002764 19 0.014
cellular response to extracellular stimulus GO:0031668 73 0.014
amide transport GO:0042886 105 0.014
response to purine containing compound GO:0014074 126 0.014
tissue regeneration GO:0042246 36 0.014
leukocyte mediated immunity GO:0002443 28 0.014
g protein coupled receptor signaling pathway GO:0007186 242 0.013
regulation of blood vessel size GO:0050880 89 0.013
regulation of molecular function GO:0065009 398 0.013
cellular response to peptide hormone stimulus GO:0071375 120 0.013
organelle organization GO:0006996 266 0.013
negative regulation of protein metabolic process GO:0051248 114 0.013
positive regulation of cell projection organization GO:0031346 111 0.013
salivary gland morphogenesis GO:0007435 1 0.013
regulation of body fluid levels GO:0050878 90 0.013
protein complex subunit organization GO:0071822 302 0.013
positive regulation of protein phosphorylation GO:0001934 135 0.013
positive regulation of neurogenesis GO:0050769 165 0.013
regulation of phosphorus metabolic process GO:0051174 349 0.013
negative regulation of response to stimulus GO:0048585 155 0.013
positive regulation of phosphate metabolic process GO:0045937 262 0.013
cell morphogenesis involved in neuron differentiation GO:0048667 106 0.013
regulation of muscle system process GO:0090257 79 0.013
cellular response to alcohol GO:0097306 87 0.013
alcohol metabolic process GO:0006066 77 0.013
organonitrogen compound catabolic process GO:1901565 179 0.013
positive regulation of programmed cell death GO:0043068 157 0.013
steroid metabolic process GO:0008202 73 0.013
neuron apoptotic process GO:0051402 88 0.013
single organism cellular localization GO:1902580 102 0.013
regulation of membrane potential GO:0042391 110 0.012
mesoderm development GO:0007498 2 0.012
embryonic pattern specification GO:0009880 1 0.012
fatty acid derivative metabolic process GO:1901568 38 0.012
muscle tissue development GO:0060537 58 0.012
synaptic vesicle endocytosis GO:0048488 4 0.012
monocarboxylic acid biosynthetic process GO:0072330 48 0.012
positive regulation of cell death GO:0010942 184 0.012
nucleoside phosphate biosynthetic process GO:1901293 102 0.012
peptide hormone secretion GO:0030072 84 0.012
regulation of tube size GO:0035150 89 0.012
anterior posterior pattern specification GO:0009952 1 0.012
positive regulation of transcription dna templated GO:0045893 197 0.012
cellular response to insulin stimulus GO:0032869 81 0.012
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.012
regulation of reactive oxygen species metabolic process GO:2000377 26 0.012
neurological system process GO:0050877 219 0.012
negative regulation of secretion GO:0051048 82 0.012
insulin secretion GO:0030073 69 0.012
gland development GO:0048732 155 0.012
single organismal cell cell adhesion GO:0016337 42 0.012
cellular component movement GO:0006928 248 0.012
regulation of mapk cascade GO:0043408 116 0.012
mapk cascade GO:0000165 140 0.012
regulation of cell morphogenesis involved in differentiation GO:0010769 72 0.012
hormone secretion GO:0046879 115 0.012
neuron development GO:0048666 286 0.012
cell activation involved in immune response GO:0002263 16 0.012
neuron projection morphogenesis GO:0048812 122 0.012
regulation of epithelial cell proliferation GO:0050678 49 0.012
muscle organ development GO:0007517 50 0.012
regulation of homotypic cell cell adhesion GO:0034110 4 0.012
circulatory system development GO:0072359 134 0.012
heart morphogenesis GO:0003007 3 0.012
respiratory system development GO:0060541 45 0.011
response to metal ion GO:0010038 253 0.011
regulation of hormone secretion GO:0046883 106 0.011
ribose phosphate metabolic process GO:0019693 235 0.011
calcium ion transport GO:0006816 131 0.011
cytokine biosynthetic process GO:0042089 3 0.011
endocytosis GO:0006897 84 0.011
development of primary sexual characteristics GO:0045137 107 0.011
regulation of lipid biosynthetic process GO:0046890 38 0.011
positive regulation of neuron projection development GO:0010976 99 0.011
response to activity GO:0014823 73 0.011
vascular process in circulatory system GO:0003018 96 0.011
cellular amide metabolic process GO:0043603 44 0.011
response to starvation GO:0042594 59 0.011
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.011
liver development GO:0001889 90 0.011
positive regulation of immune system process GO:0002684 90 0.011
cellular response to oxidative stress GO:0034599 76 0.011
positive regulation of kinase activity GO:0033674 77 0.011
cell motility GO:0048870 202 0.011
organelle localization GO:0051640 55 0.011
cellular response to lipid GO:0071396 201 0.011
cell morphogenesis involved in differentiation GO:0000904 119 0.011
positive regulation of locomotion GO:0040017 102 0.011
response to fatty acid GO:0070542 65 0.011
regulation of b cell mediated immunity GO:0002712 2 0.011
regulation of response to wounding GO:1903034 69 0.011
exocytosis GO:0006887 60 0.011
regulation of endocytosis GO:0030100 42 0.011
macromolecular complex subunit organization GO:0043933 339 0.011
multicellular organismal signaling GO:0035637 44 0.011
axis specification GO:0009798 4 0.011
ion homeostasis GO:0050801 212 0.011
negative regulation of rna biosynthetic process GO:1902679 118 0.011
regulation of immune response GO:0050776 55 0.010
regulation of ion transmembrane transport GO:0034765 121 0.010
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.010
muscle contraction GO:0006936 88 0.010
tube development GO:0035295 89 0.010
protein maturation GO:0051604 68 0.010
establishment of organelle localization GO:0051656 37 0.010
positive regulation of transferase activity GO:0051347 81 0.010
single organism organelle organization GO:1902589 180 0.010
hair cycle process GO:0022405 2 0.010
regulation of synaptic transmission GO:0050804 141 0.010
decidualization GO:0046697 14 0.010
negative regulation of cellular protein metabolic process GO:0032269 106 0.010
gastrulation GO:0007369 2 0.010
negative regulation of neuron death GO:1901215 69 0.010
regulation of cell morphogenesis GO:0022604 77 0.010
negative regulation of cellular component organization GO:0051129 83 0.010
negative regulation of neurogenesis GO:0050768 78 0.010

Lgmn disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.068
musculoskeletal system disease DOID:17 0 0.068
nervous system disease DOID:863 0 0.045
disease of metabolism DOID:0014667 0 0.027
inherited metabolic disorder DOID:655 0 0.026
sensory system disease DOID:0050155 0 0.018
connective tissue disease DOID:65 0 0.013
immune system disease DOID:2914 0 0.012
central nervous system disease DOID:331 0 0.011