Rattus norvegicus

0 known processes

Apc2

adenomatosis polyposis coli 2

Apc2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
neuron differentiation GO:0030182 368 0.103
Rat
regulation of rna metabolic process GO:0051252 391 0.080
homeostatic process GO:0042592 331 0.069
regulation of nucleic acid templated transcription GO:1903506 380 0.068
regulation of cellular component organization GO:0051128 368 0.065
neuron development GO:0048666 286 0.063
Rat
head development GO:0060322 247 0.063
cellular homeostasis GO:0019725 252 0.062
rna metabolic process GO:0016070 406 0.061
brain development GO:0007420 247 0.061
central nervous system development GO:0007417 311 0.059
nucleic acid templated transcription GO:0097659 379 0.057
regulation of rna biosynthetic process GO:2001141 381 0.052
regulation of cell differentiation GO:0045595 320 0.050
transcription dna templated GO:0006351 377 0.050
rna biosynthetic process GO:0032774 380 0.047
chemical homeostasis GO:0048878 292 0.047
cation transmembrane transport GO:0098655 263 0.046
cellular component assembly GO:0022607 360 0.046
neuron projection development GO:0031175 273 0.045
Rat
regulation of ion transport GO:0043269 245 0.044
organophosphate metabolic process GO:0019637 370 0.043
anatomical structure morphogenesis GO:0009653 298 0.043
metal ion homeostasis GO:0055065 186 0.042
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.042
cellular metal ion homeostasis GO:0006875 172 0.041
intracellular signal transduction GO:0035556 314 0.041
transcription from rna polymerase ii promoter GO:0006366 252 0.041
regulation of multicellular organismal development GO:2000026 376 0.040
calcium ion homeostasis GO:0055074 162 0.040
regulation of nervous system development GO:0051960 264 0.040
cellular component movement GO:0006928 248 0.040
cation homeostasis GO:0055080 195 0.040
regulation of transcription dna templated GO:0006355 374 0.038
response to metal ion GO:0010038 253 0.038
regulation of neuron differentiation GO:0045664 208 0.037
ion transmembrane transport GO:0034220 365 0.037
nucleobase containing small molecule metabolic process GO:0055086 316 0.037
regulation of cell development GO:0060284 263 0.036
cellular ion homeostasis GO:0006873 184 0.036
carboxylic acid metabolic process GO:0019752 289 0.036
Rat
negative regulation of metabolic process GO:0009892 331 0.035
organelle organization GO:0006996 266 0.035
programmed cell death GO:0012501 392 0.034
single organism catabolic process GO:0044712 283 0.034
positive regulation of multicellular organismal process GO:0051240 387 0.034
locomotion GO:0040011 237 0.034
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.033
rhythmic process GO:0048511 156 0.032
cell projection organization GO:0030030 302 0.032
Rat
cellular divalent inorganic cation homeostasis GO:0072503 162 0.032
cation transport GO:0006812 382 0.032
inorganic cation transmembrane transport GO:0098662 202 0.032
cellular chemical homeostasis GO:0055082 247 0.031
ion homeostasis GO:0050801 212 0.031
apoptotic process GO:0006915 381 0.031
amine metabolic process GO:0009308 38 0.031
Rat
cellular calcium ion homeostasis GO:0006874 160 0.030
positive regulation of cellular biosynthetic process GO:0031328 295 0.030
transmembrane transport GO:0055085 412 0.029
positive regulation of phosphate metabolic process GO:0045937 262 0.029
positive regulation of cell differentiation GO:0045597 217 0.029
regulation of cellular ketone metabolic process GO:0010565 27 0.029
Rat
response to nutrient levels GO:0031667 370 0.029
single organism intracellular transport GO:1902582 166 0.029
Human
nucleoside triphosphate catabolic process GO:0009143 123 0.028
response to inorganic substance GO:0010035 377 0.028
cellular amine metabolic process GO:0044106 38 0.028
Rat
cellular amino acid metabolic process GO:0006520 107 0.027
Rat
positive regulation of ion transport GO:0043270 94 0.027
purine nucleotide metabolic process GO:0006163 229 0.026
response to extracellular stimulus GO:0009991 380 0.026
protein complex subunit organization GO:0071822 302 0.026
nucleoside phosphate metabolic process GO:0006753 283 0.026
carbohydrate derivative metabolic process GO:1901135 346 0.026
cell motility GO:0048870 202 0.026
cellular response to endogenous stimulus GO:0071495 377 0.026
Rat
regulation of apoptotic process GO:0042981 335 0.026
cell projection morphogenesis GO:0048858 123 0.026
regulation of molecular function GO:0065009 398 0.026
multicellular organism reproduction GO:0032504 233 0.025
inorganic ion transmembrane transport GO:0098660 229 0.025
glycosyl compound metabolic process GO:1901657 182 0.025
positive regulation of biosynthetic process GO:0009891 319 0.025
divalent inorganic cation homeostasis GO:0072507 165 0.024
regulation of cell projection organization GO:0031344 175 0.024
reproduction GO:0000003 245 0.024
reproductive process GO:0022414 372 0.024
cellular component biogenesis GO:0044085 368 0.024
cellular response to hormone stimulus GO:0032870 247 0.024
positive regulation of cell development GO:0010720 176 0.024
anatomical structure formation involved in morphogenesis GO:0048646 83 0.024
cell migration GO:0016477 197 0.024
positive regulation of cell projection organization GO:0031346 111 0.024
positive regulation of neurogenesis GO:0050769 165 0.024
regulation of cellular amine metabolic process GO:0033238 8 0.024
Rat
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.024
negative regulation of cellular biosynthetic process GO:0031327 161 0.024
multi organism reproductive process GO:0044703 262 0.023
protein phosphorylation GO:0006468 345 0.023
regeneration GO:0031099 163 0.023
macromolecular complex subunit organization GO:0043933 339 0.023
cell cell signaling GO:0007267 335 0.023
circulatory system development GO:0072359 134 0.023
regulation of neuron projection development GO:0010975 161 0.023
cell part morphogenesis GO:0032990 123 0.023
negative regulation of cell communication GO:0010648 158 0.023
Human
single organism reproductive process GO:0044702 297 0.023
regulation of sodium ion transmembrane transporter activity GO:2000649 4 0.023
cytosolic calcium ion homeostasis GO:0051480 140 0.023
positive regulation of cell death GO:0010942 184 0.023
regulation of anatomical structure morphogenesis GO:0022603 141 0.023
response to nutrient GO:0007584 248 0.023
cellular ketone metabolic process GO:0042180 51 0.023
Rat
monovalent inorganic cation transport GO:0015672 172 0.022
purine containing compound metabolic process GO:0072521 253 0.022
positive regulation of response to stimulus GO:0048584 285 0.022
protein complex assembly GO:0006461 263 0.022
organic substance catabolic process GO:1901575 316 0.022
oxoacid metabolic process GO:0043436 290 0.022
Rat
positive regulation of nucleic acid templated transcription GO:1903508 197 0.022
protein complex biogenesis GO:0070271 263 0.022
macromolecule localization GO:0033036 252 0.022
Human
ras protein signal transduction GO:0007265 29 0.022
cellular component morphogenesis GO:0032989 155 0.022
appendage morphogenesis GO:0035107 4 0.022
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.022
g protein coupled receptor signaling pathway GO:0007186 242 0.022
cellular cation homeostasis GO:0030003 180 0.022
negative regulation of cellular metabolic process GO:0031324 281 0.021
response to growth factor GO:0070848 189 0.021
Rat
metal ion transport GO:0030001 289 0.021
cellular response to lipid GO:0071396 201 0.021
positive regulation of developmental process GO:0051094 283 0.021
neuron projection morphogenesis GO:0048812 122 0.021
multicellular organismal reproductive process GO:0048609 233 0.021
cardiovascular system development GO:0072358 134 0.021
catabolic process GO:0009056 351 0.021
purine ribonucleotide metabolic process GO:0009150 227 0.021
lipid metabolic process GO:0006629 283 0.021
negative regulation of gene expression GO:0010629 199 0.020
organonitrogen compound catabolic process GO:1901565 179 0.020
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.020
regulation of cell morphogenesis involved in differentiation GO:0010769 72 0.020
nucleotide metabolic process GO:0009117 279 0.020
sexual reproduction GO:0019953 148 0.020
forebrain development GO:0030900 98 0.020
positive regulation of neuron projection development GO:0010976 99 0.020
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.020
negative regulation of biosynthetic process GO:0009890 168 0.020
single organism biosynthetic process GO:0044711 342 0.020
regulation of cellular amino acid metabolic process GO:0006521 2 0.020
Rat
positive regulation of nervous system development GO:0051962 178 0.019
localization of cell GO:0051674 202 0.019
negative regulation of macromolecule metabolic process GO:0010605 260 0.019
ribonucleoside triphosphate catabolic process GO:0009203 122 0.019
negative regulation of rna biosynthetic process GO:1902679 118 0.019
regulation of signal transduction GO:0009966 318 0.019
Human
macromolecular complex assembly GO:0065003 273 0.019
behavior GO:0007610 205 0.019
positive regulation of gene expression GO:0010628 244 0.019
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.019
regulation of metal ion transport GO:0010959 118 0.019
protein oligomerization GO:0051259 191 0.019
cell morphogenesis GO:0000902 142 0.019
learning or memory GO:0007611 90 0.018
synaptic transmission GO:0007268 235 0.018
heart morphogenesis GO:0003007 3 0.018
positive regulation of neuron differentiation GO:0045666 126 0.018
positive regulation of rna biosynthetic process GO:1902680 197 0.018
ribose phosphate metabolic process GO:0019693 235 0.018
response to hypoxia GO:0001666 231 0.018
negative regulation of nucleic acid templated transcription GO:1903507 117 0.018
positive regulation of transcription dna templated GO:0045893 197 0.018
cellular response to organic cyclic compound GO:0071407 202 0.018
neurotransmitter uptake GO:0001504 3 0.018
response to carbohydrate GO:0009743 183 0.018
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.018
response to acid chemical GO:0001101 222 0.018
purine nucleotide catabolic process GO:0006195 136 0.018
positive regulation of rna metabolic process GO:0051254 203 0.018
nucleobase containing compound catabolic process GO:0034655 152 0.018
negative regulation of multicellular organismal process GO:0051241 203 0.018
secretion GO:0046903 307 0.017
positive regulation of cytosolic calcium ion concentration GO:0007204 122 0.017
response to oxidative stress GO:0006979 186 0.017
regulation of phosphate metabolic process GO:0019220 349 0.017
regulation of cell proliferation GO:0042127 359 0.017
neurological system process GO:0050877 219 0.017
cellular response to stress GO:0033554 269 0.017
ribonucleotide metabolic process GO:0009259 231 0.017
positive regulation of phosphorus metabolic process GO:0010562 262 0.017
positive regulation of cellular amine metabolic process GO:0033240 3 0.017
response to monosaccharide GO:0034284 159 0.017
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.017
positive regulation of signaling GO:0023056 270 0.017
small gtpase mediated signal transduction GO:0007264 36 0.016
organic cyclic compound catabolic process GO:1901361 175 0.016
carbohydrate derivative biosynthetic process GO:1901137 124 0.016
divalent inorganic cation transport GO:0072511 134 0.016
organic acid metabolic process GO:0006082 292 0.016
Rat
purine nucleoside metabolic process GO:0042278 169 0.016
aromatic compound catabolic process GO:0019439 168 0.016
adult locomotory behavior GO:0008344 4 0.016
regulation of transmembrane transport GO:0034762 122 0.016
regulation of neurogenesis GO:0050767 247 0.016
cellular response to growth factor stimulus GO:0071363 162 0.016
Rat
anion transport GO:0006820 178 0.016
response to reactive oxygen species GO:0000302 120 0.016
cell communication involved in cardiac conduction GO:0086065 2 0.016
positive regulation of cellular component organization GO:0051130 200 0.016
telencephalon development GO:0021537 62 0.015
cellular response to oxygen containing compound GO:1901701 386 0.015
potassium ion transport GO:0006813 97 0.015
leukocyte cell cell adhesion GO:0007159 4 0.015
regulation of membrane potential GO:0042391 110 0.015
nitrogen compound transport GO:0071705 229 0.015
positive regulation of phosphorylation GO:0042327 177 0.015
cellular response to external stimulus GO:0071496 118 0.015
nucleoside metabolic process GO:0009116 179 0.015
sodium ion transport GO:0006814 82 0.015
regulation of cellular component movement GO:0051270 150 0.015
cellular catabolic process GO:0044248 295 0.015
organophosphate catabolic process GO:0046434 148 0.015
axis specification GO:0009798 4 0.015
positive regulation of catalytic activity GO:0043085 184 0.015
tissue development GO:0009888 252 0.015
embryonic appendage morphogenesis GO:0035113 4 0.014
cell morphogenesis involved in differentiation GO:0000904 119 0.014
cellular nitrogen compound catabolic process GO:0044270 163 0.014
negative regulation of transcription dna templated GO:0045892 116 0.014
ribonucleoside metabolic process GO:0009119 174 0.014
divalent metal ion transport GO:0070838 132 0.014
growth GO:0040007 165 0.014
regulation of hormone levels GO:0010817 187 0.014
nucleotide catabolic process GO:0009166 139 0.014
negative regulation of rna metabolic process GO:0051253 123 0.014
organic acid transport GO:0015849 116 0.014
purine ribonucleoside catabolic process GO:0046130 124 0.014
ribonucleoside triphosphate metabolic process GO:0009199 141 0.014
positive regulation of signal transduction GO:0009967 175 0.014
regulation of cellular localization GO:0060341 263 0.014
Human
muscle contraction GO:0006936 88 0.014
regulation of ion transmembrane transporter activity GO:0032412 48 0.014
single organism behavior GO:0044708 130 0.014
calcium ion transport GO:0006816 131 0.014
regulation of cellular protein metabolic process GO:0032268 267 0.014
amide transport GO:0042886 105 0.014
purine nucleoside triphosphate metabolic process GO:0009144 141 0.014
regulation of protein metabolic process GO:0051246 289 0.014
response to decreased oxygen levels GO:0036293 237 0.014
glycosyl compound catabolic process GO:1901658 126 0.013
positive regulation of transport GO:0051050 245 0.013
cognition GO:0050890 92 0.013
regulation of anatomical structure size GO:0090066 135 0.013
response to estradiol GO:0032355 164 0.013
respiratory gaseous exchange GO:0007585 4 0.013
axon development GO:0061564 96 0.013
ribonucleotide biosynthetic process GO:0009260 85 0.013
axonogenesis GO:0007409 71 0.013
regulation of cell morphogenesis GO:0022604 77 0.013
organic anion transport GO:0015711 132 0.013
response to alkaloid GO:0043279 132 0.013
developmental process involved in reproduction GO:0003006 159 0.013
ribonucleotide catabolic process GO:0009261 136 0.013
response to ketone GO:1901654 182 0.013
response to hydrogen peroxide GO:0042542 89 0.013
regulation of phosphorylation GO:0042325 248 0.013
neuromuscular process GO:0050905 2 0.013
gland development GO:0048732 155 0.013
regulation of intracellular signal transduction GO:1902531 218 0.012
regulation of transmembrane transporter activity GO:0022898 49 0.012
response to estrogen GO:0043627 232 0.012
regulation of phosphorus metabolic process GO:0051174 349 0.012
regulation of secretion by cell GO:1903530 208 0.012
secretion by cell GO:0032940 248 0.012
dephosphorylation GO:0016311 98 0.012
aging GO:0007568 241 0.012
male gamete generation GO:0048232 99 0.012
cell cell signaling involved in cell fate commitment GO:0045168 2 0.012
regulation of transporter activity GO:0032409 50 0.012
bmp signaling pathway GO:0030509 4 0.012
positive regulation of intracellular signal transduction GO:1902533 138 0.012
purine ribonucleoside triphosphate catabolic process GO:0009207 122 0.012
cellular response to nitrogen compound GO:1901699 210 0.012
heart contraction GO:0060047 57 0.012
nucleoside phosphate biosynthetic process GO:1901293 102 0.012
negative regulation of transport GO:0051051 136 0.012
Human
ribose phosphate biosynthetic process GO:0046390 87 0.012
single organism organelle organization GO:1902589 180 0.012
cardiac conduction GO:0061337 2 0.012
response to other organism GO:0051707 220 0.012
protein homooligomerization GO:0051260 91 0.012
peptidyl amino acid modification GO:0018193 126 0.012
protein localization GO:0008104 191 0.012
Human
motor neuron axon guidance GO:0008045 1 0.012
neuronal action potential GO:0019228 35 0.012
nucleoside phosphate catabolic process GO:1901292 140 0.012
sex differentiation GO:0007548 113 0.011
oligopeptide transport GO:0006857 4 0.011
sodium ion transmembrane transport GO:0035725 67 0.011
cardiac chamber development GO:0003205 1 0.011
organ regeneration GO:0031100 101 0.011
regulation of catalytic activity GO:0050790 304 0.011
cell morphogenesis involved in neuron differentiation GO:0048667 106 0.011
response to wounding GO:0009611 254 0.011
response to glucose GO:0009749 136 0.011
positive regulation of molecular function GO:0044093 230 0.011
positive regulation of programmed cell death GO:0043068 157 0.011
ribonucleoside catabolic process GO:0042454 126 0.011
protein transport GO:0015031 132 0.011
Human
eye morphogenesis GO:0048592 4 0.011
muscle structure development GO:0061061 87 0.011
cellular response to acid chemical GO:0071229 75 0.011
positive regulation of apoptotic process GO:0043065 154 0.011
regulation of programmed cell death GO:0043067 341 0.011
regulation of response to stress GO:0080134 126 0.011
purine ribonucleoside metabolic process GO:0046128 168 0.011
cellular response to organonitrogen compound GO:0071417 197 0.011
gamete generation GO:0007276 124 0.011
negative regulation of cell proliferation GO:0008285 119 0.011
response to peptide hormone GO:0043434 278 0.011
regulation of cell migration GO:0030334 128 0.011
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.011
limb morphogenesis GO:0035108 4 0.011
mesoderm development GO:0007498 2 0.011
response to glucocorticoid GO:0051384 223 0.011
negative regulation of neuron differentiation GO:0045665 62 0.011
nucleoside triphosphate metabolic process GO:0009141 144 0.011
regulation of growth GO:0040008 105 0.011
sensory perception GO:0007600 101 0.011
positive regulation of cellular protein metabolic process GO:0032270 167 0.011
response to purine containing compound GO:0014074 126 0.011
cytoplasmic transport GO:0016482 115 0.011
Human
cellular component maintenance GO:0043954 4 0.011
heterocycle catabolic process GO:0046700 167 0.011
spermatogenesis GO:0007283 99 0.011
lipid biosynthetic process GO:0008610 128 0.011
response to mechanical stimulus GO:0009612 134 0.011
regulation of system process GO:0044057 208 0.010
response to vitamin GO:0033273 131 0.010
multi multicellular organism process GO:0044706 138 0.010
gastrulation GO:0007369 2 0.010
response to camp GO:0051591 91 0.010
centrosome cycle GO:0007098 1 0.010
sequestering of calcium ion GO:0051208 8 0.010
positive regulation of protein metabolic process GO:0051247 178 0.010
response to increased oxygen levels GO:0036296 45 0.010
regulation of transcription regulatory region dna binding GO:2000677 4 0.010
hepaticobiliary system development GO:0061008 90 0.010
organ formation GO:0048645 3 0.010
regulation of hydrolase activity GO:0051336 143 0.010
regulation of tube size GO:0035150 89 0.010
dendrite development GO:0016358 72 0.010
response to radiation GO:0009314 137 0.010
muscle tissue development GO:0060537 58 0.010
circadian rhythm GO:0007623 88 0.010
mitotic spindle organization GO:0007052 2 0.010
circulatory system process GO:0003013 183 0.010
response to hexose GO:0009746 144 0.010
neuron death GO:0070997 127 0.010
peptide hormone secretion GO:0030072 84 0.010

Apc2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.037
nervous system disease DOID:863 0 0.037
central nervous system disease DOID:331 0 0.029
brain disease DOID:936 0 0.029
disease of cellular proliferation DOID:14566 0 0.015
cancer DOID:162 0 0.015
organ system cancer DOID:0050686 0 0.014
epilepsy syndrome DOID:1826 0 0.012
electroclinical syndrome DOID:0050701 0 0.012
musculoskeletal system disease DOID:17 0 0.011
myopathy DOID:423 0 0.011
muscular disease DOID:0080000 0 0.011
muscular dystrophy DOID:9884 0 0.011
muscle tissue disease DOID:66 0 0.011