Rattus norvegicus

104 known processes

Adrbk2

adrenergic, beta, receptor kinase 2

(Aliases: Grk3)

Adrbk2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
ion transmembrane transport GO:0034220 365 0.638
striated muscle contraction GO:0006941 44 0.285
regulation of cellular localization GO:0060341 263 0.249
regulation of secretion by cell GO:1903530 208 0.231
secretion by cell GO:0032940 248 0.228
regulation of hormone levels GO:0010817 187 0.178
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.152
carboxylic acid metabolic process GO:0019752 289 0.147
regulation of molecular function GO:0065009 398 0.145
positive regulation of secretion by cell GO:1903532 128 0.143
regulation of amine transport GO:0051952 54 0.140
neuron differentiation GO:0030182 368 0.139
transmembrane transport GO:0055085 412 0.120
inorganic ion transmembrane transport GO:0098660 229 0.119
neurological system process GO:0050877 219 0.119
cellular response to organic cyclic compound GO:0071407 202 0.118
regulation of nucleic acid templated transcription GO:1903506 380 0.112
catecholamine transport GO:0051937 37 0.110
regulation of hormone secretion GO:0046883 106 0.109
organic acid metabolic process GO:0006082 292 0.104
cellular component assembly GO:0022607 360 0.103
response to alkaloid GO:0043279 132 0.101
negative regulation of immune system process GO:0002683 39 0.101
response to metal ion GO:0010038 253 0.099
positive regulation of rna metabolic process GO:0051254 203 0.095
cell cell signaling GO:0007267 335 0.094
cellular component movement GO:0006928 248 0.092
cation transport GO:0006812 382 0.091
synaptic transmission GO:0007268 235 0.089
hormone transport GO:0009914 121 0.088
oxoacid metabolic process GO:0043436 290 0.088
secretion GO:0046903 307 0.086
positive regulation of cellular biosynthetic process GO:0031328 295 0.082
regulation of synaptic transmission GO:0050804 141 0.082
inorganic cation transmembrane transport GO:0098662 202 0.080
negative regulation of natural killer cell mediated immunity GO:0002716 4 0.075
cellular amino acid metabolic process GO:0006520 107 0.072
organic hydroxy compound transport GO:0015850 77 0.072
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.071
calcium ion transmembrane transport GO:0070588 70 0.070
muscle contraction GO:0006936 88 0.069
regulation of multicellular organismal development GO:2000026 376 0.069
positive regulation of cell communication GO:0010647 271 0.068
positive regulation of cell proliferation GO:0008284 249 0.065
protein complex biogenesis GO:0070271 263 0.064
anatomical structure morphogenesis GO:0009653 298 0.060
nucleic acid templated transcription GO:0097659 379 0.060
rna metabolic process GO:0016070 406 0.060
nitrogen compound transport GO:0071705 229 0.059
regulation of intracellular signal transduction GO:1902531 218 0.058
negative regulation of signaling GO:0023057 157 0.057
positive regulation of amine transport GO:0051954 26 0.056
protein complex assembly GO:0006461 263 0.055
amino acid transport GO:0006865 70 0.053
macromolecular complex subunit organization GO:0043933 339 0.052
cellular response to growth factor stimulus GO:0071363 162 0.051
rhythmic process GO:0048511 156 0.051
cellular component biogenesis GO:0044085 368 0.050
positive regulation of biosynthetic process GO:0009891 319 0.049
prostate gland epithelium morphogenesis GO:0060740 2 0.049
neurotransmitter transport GO:0006836 42 0.049
protein complex subunit organization GO:0071822 302 0.049
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.049
positive regulation of rna biosynthetic process GO:1902680 197 0.048
cellular carbohydrate metabolic process GO:0044262 72 0.047
vesicle mediated transport GO:0016192 181 0.047
regulation of transcription dna templated GO:0006355 374 0.047
positive regulation of nucleic acid templated transcription GO:1903508 197 0.045
behavior GO:0007610 205 0.045
negative regulation of cellular metabolic process GO:0031324 281 0.044
protein oligomerization GO:0051259 191 0.044
anion transport GO:0006820 178 0.044
divalent metal ion transport GO:0070838 132 0.044
signal release GO:0023061 145 0.044
regulation of signal transduction GO:0009966 318 0.044
heart process GO:0003015 57 0.043
regulation of programmed cell death GO:0043067 341 0.042
single organism behavior GO:0044708 130 0.042
membrane organization GO:0061024 94 0.042
transcription from rna polymerase ii promoter GO:0006366 252 0.042
striated muscle tissue development GO:0014706 58 0.042
prostate gland morphogenesis GO:0060512 2 0.042
response to external biotic stimulus GO:0043207 221 0.040
sensory perception GO:0007600 101 0.040
neuron projection development GO:0031175 273 0.039
response to nutrient GO:0007584 248 0.039
neuron development GO:0048666 286 0.039
positive regulation of gene expression GO:0010628 244 0.038
central nervous system development GO:0007417 311 0.038
amine transport GO:0015837 57 0.038
positive regulation of transcription dna templated GO:0045893 197 0.038
synaptic vesicle localization GO:0097479 24 0.037
regulation of ion transport GO:0043269 245 0.037
macromolecular complex assembly GO:0065003 273 0.037
amine metabolic process GO:0009308 38 0.037
neuron projection morphogenesis GO:0048812 122 0.037
positive regulation of transport GO:0051050 245 0.037
negative regulation of immune response to tumor cell GO:0002838 2 0.037
cell projection organization GO:0030030 302 0.036
negative regulation of vesicle fusion GO:0031339 2 0.036
positive regulation of synaptic transmission GO:0050806 62 0.036
regulation of system process GO:0044057 208 0.035
cellular response to nitrogen compound GO:1901699 210 0.035
cellular response to lipid GO:0071396 201 0.035
negative regulation of response to stimulus GO:0048585 155 0.035
single organism carbohydrate metabolic process GO:0044723 118 0.034
positive regulation of programmed cell death GO:0043068 157 0.034
positive regulation of secretion GO:0051047 140 0.034
regulation of blood circulation GO:1903522 110 0.034
organophosphate biosynthetic process GO:0090407 143 0.034
intracellular signal transduction GO:0035556 314 0.034
cellular ketone metabolic process GO:0042180 51 0.033
negative regulation of signal transduction GO:0009968 83 0.033
single organism reproductive process GO:0044702 297 0.033
cation transmembrane transport GO:0098655 263 0.033
response to inorganic substance GO:0010035 377 0.033
negative regulation of cell communication GO:0010648 158 0.033
protein heterooligomerization GO:0051291 89 0.033
cellular amine metabolic process GO:0044106 38 0.033
metal ion transport GO:0030001 289 0.032
regulation of peptide transport GO:0090087 87 0.032
macromolecule localization GO:0033036 252 0.032
carbohydrate metabolic process GO:0005975 130 0.032
negative regulation of metabolic process GO:0009892 331 0.032
regulation of peptide hormone secretion GO:0090276 80 0.032
positive regulation of multicellular organismal process GO:0051240 387 0.032
positive regulation of cellular component organization GO:0051130 200 0.032
cellular response to endogenous stimulus GO:0071495 377 0.032
regulation of phosphorus metabolic process GO:0051174 349 0.031
regulation of rna metabolic process GO:0051252 391 0.031
transcription dna templated GO:0006351 377 0.031
response to amine GO:0014075 46 0.031
carboxylic acid transport GO:0046942 115 0.030
regulation of cell proliferation GO:0042127 359 0.030
rna biosynthetic process GO:0032774 380 0.030
monoamine transport GO:0015844 43 0.029
negative regulation of innate immune response GO:0045824 4 0.029
regulation of cellular amino acid metabolic process GO:0006521 2 0.029
cell migration GO:0016477 197 0.029
negative regulation of cell proliferation GO:0008285 119 0.029
response to estrogen GO:0043627 232 0.029
positive regulation of signaling GO:0023056 270 0.029
endoplasmic reticulum to cytosol transport GO:1903513 4 0.028
response to cocaine GO:0042220 39 0.028
regulation of protein metabolic process GO:0051246 289 0.028
brain development GO:0007420 247 0.028
enzyme linked receptor protein signaling pathway GO:0007167 116 0.028
small molecule biosynthetic process GO:0044283 124 0.028
muscle system process GO:0003012 115 0.028
cellular response to organonitrogen compound GO:0071417 197 0.028
regulation of response to stress GO:0080134 126 0.028
neuron neuron synaptic transmission GO:0007270 60 0.028
single organism membrane organization GO:0044802 74 0.028
regulation of cellular protein metabolic process GO:0032268 267 0.027
cellular lipid metabolic process GO:0044255 208 0.027
response to ethanol GO:0045471 162 0.027
release of sequestered calcium ion into cytosol by sarcoplasmic reticulum GO:0014808 4 0.027
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.027
head development GO:0060322 247 0.027
regulation of cellular ketone metabolic process GO:0010565 27 0.026
regulation of catecholamine secretion GO:0050433 32 0.026
establishment of protein localization GO:0045184 141 0.026
synapse organization GO:0050808 46 0.026
regulation of transmembrane transporter activity GO:0022898 49 0.026
negative regulation of transport GO:0051051 136 0.026
regulation of secretion GO:0051046 224 0.025
gland development GO:0048732 155 0.025
muscle structure development GO:0061061 87 0.025
response to glucocorticoid GO:0051384 223 0.025
regulation of cell development GO:0060284 263 0.025
regulation of ion transmembrane transport GO:0034765 121 0.024
defecation GO:0030421 1 0.024
cognition GO:0050890 92 0.024
negative regulation of defense response GO:0031348 19 0.024
response to hypoxia GO:0001666 231 0.024
cell part morphogenesis GO:0032990 123 0.023
cellular response to peptide GO:1901653 133 0.023
cellular response to oxygen containing compound GO:1901701 386 0.023
cell projection morphogenesis GO:0048858 123 0.023
positive regulation of developmental process GO:0051094 283 0.023
peptide hormone secretion GO:0030072 84 0.023
cellular protein localization GO:0034613 122 0.023
regulation of neurogenesis GO:0050767 247 0.023
regulation of organic acid transport GO:0032890 35 0.023
sarcoplasmic reticulum calcium ion transport GO:0070296 8 0.023
regulation of anatomical structure morphogenesis GO:0022603 141 0.023
cytoplasmic transport GO:0016482 115 0.022
tripeptide transport GO:0042939 2 0.022
monosaccharide metabolic process GO:0005996 61 0.022
apoptotic process GO:0006915 381 0.022
regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum GO:0010880 4 0.022
regulation of ion transmembrane transporter activity GO:0032412 48 0.022
protein homooligomerization GO:0051260 91 0.022
peptide transport GO:0015833 97 0.022
carbohydrate catabolic process GO:0016052 40 0.022
regulation of lipid metabolic process GO:0019216 68 0.022
regulation of membrane potential GO:0042391 110 0.022
regulation of muscle contraction GO:0006937 53 0.022
regulation of peptide secretion GO:0002791 82 0.021
calcium ion transport from endoplasmic reticulum to cytosol GO:1903514 4 0.021
regulation of transporter activity GO:0032409 50 0.021
cell cycle GO:0007049 101 0.021
cellular macromolecule localization GO:0070727 122 0.021
positive regulation of protein modification process GO:0031401 142 0.021
neuron death GO:0070997 127 0.021
positive regulation of signal transduction GO:0009967 175 0.021
calcium ion transport GO:0006816 131 0.021
positive regulation of intracellular signal transduction GO:1902533 138 0.021
regulation of muscle system process GO:0090257 79 0.021
mesoderm development GO:0007498 2 0.021
regulation of neuron projection development GO:0010975 161 0.021
tissue development GO:0009888 252 0.021
glycerolipid metabolic process GO:0046486 67 0.021
neuromuscular process GO:0050905 2 0.021
regulation of cellular amine metabolic process GO:0033238 8 0.021
phasic smooth muscle contraction GO:0014821 3 0.020
response to nutrient levels GO:0031667 370 0.020
amide transport GO:0042886 105 0.020
lipid metabolic process GO:0006629 283 0.020
positive regulation of catecholamine secretion GO:0033605 13 0.020
programmed cell death GO:0012501 392 0.020
cardiac muscle contraction GO:0060048 27 0.020
formation of primary germ layer GO:0001704 1 0.020
multicellular organism reproduction GO:0032504 233 0.020
positive regulation of neurogenesis GO:0050769 165 0.020
response to other organism GO:0051707 220 0.020
response to activity GO:0014823 73 0.020
regulation of neurological system process GO:0031644 43 0.020
response to oxygen levels GO:0070482 265 0.020
response to ammonium ion GO:0060359 71 0.020
muscle tissue development GO:0060537 58 0.020
regulation of rna biosynthetic process GO:2001141 381 0.020
peptidyl amino acid modification GO:0018193 126 0.020
positive regulation of phosphorus metabolic process GO:0010562 262 0.019
blood circulation GO:0008015 183 0.019
protein localization to membrane GO:0072657 36 0.019
positive regulation of the force of heart contraction by epinephrine GO:0003059 1 0.019
growth GO:0040007 165 0.019
positive regulation of cell death GO:0010942 184 0.019
immune response GO:0006955 104 0.019
dendrite development GO:0016358 72 0.019
response to extracellular stimulus GO:0009991 380 0.019
establishment or maintenance of transmembrane electrochemical gradient GO:0010248 1 0.019
regeneration GO:0031099 163 0.019
anatomical structure formation involved in morphogenesis GO:0048646 83 0.019
cellular response to cytokine stimulus GO:0071345 127 0.018
regulation of cell projection organization GO:0031344 175 0.018
cellular response to peptide hormone stimulus GO:0071375 120 0.018
regulation of protein modification process GO:0031399 194 0.018
organonitrogen compound biosynthetic process GO:1901566 167 0.018
negative regulation of developmental process GO:0051093 125 0.018
regulation of insulin secretion GO:0050796 65 0.018
response to decreased oxygen levels GO:0036293 237 0.018
divalent inorganic cation transport GO:0072511 134 0.018
response to wounding GO:0009611 254 0.018
endoplasmic reticulum membrane organization GO:0090158 1 0.018
detection of stimulus GO:0051606 24 0.018
oxidation reduction process GO:0055114 304 0.018
heart contraction GO:0060047 57 0.018
regulation of mapk cascade GO:0043408 116 0.018
cellular response to hormone stimulus GO:0032870 247 0.018
response to peptide GO:1901652 292 0.018
hemopoiesis GO:0030097 34 0.017
regulation of phosphorylation GO:0042325 248 0.017
organic acid transport GO:0015849 116 0.017
peptide secretion GO:0002790 86 0.017
endocytosis GO:0006897 84 0.017
positive regulation of phosphate metabolic process GO:0045937 262 0.017
regulation of catalytic activity GO:0050790 304 0.017
developmental induction GO:0031128 2 0.017
regulation of phosphate metabolic process GO:0019220 349 0.017
homeostatic process GO:0042592 331 0.017
organ induction GO:0001759 1 0.017
insulin secretion GO:0030073 69 0.017
single organism cellular localization GO:1902580 102 0.017
negative regulation of secretion by cell GO:1903531 72 0.017
calcium ion dependent exocytosis of neurotransmitter GO:0048791 2 0.017
positive regulation of the force of heart contraction by epinephrine norepinephrine GO:0001997 2 0.017
regulation of postsynaptic membrane potential GO:0060078 25 0.017
regulation of cell differentiation GO:0045595 320 0.017
negative regulation of nucleic acid templated transcription GO:1903507 117 0.017
lipid modification GO:0030258 52 0.017
positive regulation of kinase activity GO:0033674 77 0.017
wound healing GO:0042060 122 0.017
single organism carbohydrate catabolic process GO:0044724 40 0.017
negative regulation of vascular permeability GO:0043116 3 0.017
positive regulation of cell projection organization GO:0031346 111 0.017
positive regulation of cellular amine metabolic process GO:0033240 3 0.016
protein phosphorylation GO:0006468 345 0.016
adenylate cyclase modulating g protein coupled receptor signaling pathway GO:0007188 51 0.016
response to growth factor GO:0070848 189 0.016
regulation of carbohydrate metabolic process GO:0006109 41 0.016
response to ketone GO:1901654 182 0.016
response to peptide hormone GO:0043434 278 0.016
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.016
multicellular organismal signaling GO:0035637 44 0.016
positive regulation of phosphorylation GO:0042327 177 0.016
positive regulation of protein kinase activity GO:0045860 73 0.016
negative regulation of collagen biosynthetic process GO:0032966 4 0.016
positive regulation of molecular function GO:0044093 230 0.016
negative regulation of secretion GO:0051048 82 0.015
response to nicotine GO:0035094 51 0.015
regulation of cardiac muscle contraction GO:0055117 17 0.015
response to acid chemical GO:0001101 222 0.015
positive regulation of glutamate secretion GO:0014049 8 0.015
transmission of nerve impulse GO:0019226 42 0.015
defense response GO:0006952 194 0.015
catabolic process GO:0009056 351 0.015
positive regulation of protein metabolic process GO:0051247 178 0.015
multi organism reproductive process GO:0044703 262 0.015
establishment of organelle localization GO:0051656 37 0.015
skeletal muscle organ development GO:0060538 33 0.015
neutrophil apoptotic process GO:0001781 4 0.015
endoplasmic reticulum organization GO:0007029 1 0.015
regulation of apoptotic process GO:0042981 335 0.015
response to transition metal nanoparticle GO:1990267 122 0.015
cellular component morphogenesis GO:0032989 155 0.015
endomembrane system organization GO:0010256 48 0.015
behavioral response to nicotine GO:0035095 2 0.015
positive regulation of apoptotic process GO:0043065 154 0.015
negative regulation of hormone secretion GO:0046888 46 0.014
regulation of protein phosphorylation GO:0001932 183 0.014
regulation of nervous system development GO:0051960 264 0.014
skeletal muscle tissue development GO:0007519 31 0.014
response to blue light GO:0009637 1 0.014
catecholamine secretion GO:0050432 33 0.014
cellular modified amino acid metabolic process GO:0006575 61 0.014
organelle organization GO:0006996 266 0.014
monovalent inorganic cation transport GO:0015672 172 0.014
sequestering of calcium ion GO:0051208 8 0.014
lipid biosynthetic process GO:0008610 128 0.014
regulation of cellular carbohydrate metabolic process GO:0010675 39 0.014
startle response GO:0001964 2 0.014
single organism catabolic process GO:0044712 283 0.014
negative regulation of programmed cell death GO:0043069 183 0.014
regulation of cation channel activity GO:2001257 23 0.014
negative regulation of natural killer cell mediated cytotoxicity GO:0045953 4 0.014
hexose metabolic process GO:0019318 58 0.014
neuronal action potential GO:0019228 35 0.013
adult locomotory behavior GO:0008344 4 0.013
reproduction GO:0000003 245 0.013
response to toxic substance GO:0009636 133 0.013
learning GO:0007612 33 0.013
organic hydroxy compound metabolic process GO:1901615 115 0.013
cellular divalent inorganic cation homeostasis GO:0072503 162 0.013
detection of calcium ion GO:0005513 1 0.013
regulation of cell growth GO:0001558 85 0.013
telencephalon development GO:0021537 62 0.013
anion transmembrane transport GO:0098656 77 0.013
positive regulation of cell differentiation GO:0045597 217 0.013
regulation of calcium ion transport GO:0051924 77 0.013
regulation of synaptic plasticity GO:0048167 70 0.013
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.013
negative regulation of gene expression GO:0010629 199 0.013
regulation of heart contraction GO:0008016 48 0.013
lipid oxidation GO:0034440 30 0.013
neurotransmitter gated ion channel clustering GO:0072578 3 0.013
regulation of immune response GO:0050776 55 0.013
single organism biosynthetic process GO:0044711 342 0.013
developmental growth GO:0048589 100 0.013
circulatory system development GO:0072359 134 0.013
regulation of neurotransmitter secretion GO:0046928 19 0.013
protein localization GO:0008104 191 0.013
circadian regulation of gene expression GO:0032922 3 0.013
sequestering of metal ion GO:0051238 9 0.013
regulation of kinase activity GO:0043549 117 0.013
positive regulation of mapk cascade GO:0043410 92 0.013
defense response to gram negative bacterium GO:0050829 3 0.012
cation homeostasis GO:0055080 195 0.012
regulation of cardiac muscle contraction by calcium ion signaling GO:0010882 3 0.012
cellular carbohydrate catabolic process GO:0044275 20 0.012
action potential GO:0001508 54 0.012
positive regulation of ion transport GO:0043270 94 0.012
single organism organelle organization GO:1902589 180 0.012
response to calcium ion GO:0051592 59 0.012
detection of chemical stimulus GO:0009593 10 0.012
response to mechanical stimulus GO:0009612 134 0.012
angiogenesis GO:0001525 53 0.012
smooth muscle contraction GO:0006939 37 0.012
regulation of cellular component movement GO:0051270 150 0.012
organic anion transport GO:0015711 132 0.012
urinary tract smooth muscle contraction GO:0014848 4 0.011
limb morphogenesis GO:0035108 4 0.011
synaptic transmission glycinergic GO:0060012 2 0.011
respiratory gaseous exchange GO:0007585 4 0.011
reproductive process GO:0022414 372 0.011
synaptic vesicle transport GO:0048489 23 0.011
single organism intracellular transport GO:1902582 166 0.011
localization of cell GO:0051674 202 0.011
gliogenesis GO:0042063 93 0.011
glucose metabolic process GO:0006006 52 0.011
alcohol biosynthetic process GO:0046165 38 0.011
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.011
negative regulation of chronic inflammatory response GO:0002677 2 0.011
cellular response to glucocorticoid stimulus GO:0071385 68 0.011
regulation of establishment of protein localization GO:0070201 69 0.011
positive regulation of peptide secretion GO:0002793 52 0.011
positive regulation of long term synaptic potentiation GO:1900273 4 0.011
hepaticobiliary system development GO:0061008 90 0.011
regulation of neurotransmitter transport GO:0051588 21 0.011
response to monosaccharide GO:0034284 159 0.011
negative regulation of transcription from rna polymerase ii promoter GO:0000122 75 0.011
intracellular receptor signaling pathway GO:0030522 35 0.011
learning or memory GO:0007611 90 0.011
regulation of embryonic development GO:0045995 2 0.011
response to estradiol GO:0032355 164 0.011
adenylate cyclase inhibiting serotonin receptor signaling pathway GO:0007198 1 0.010
small gtpase mediated signal transduction GO:0007264 36 0.010
regulation of monooxygenase activity GO:0032768 8 0.010
cellular response to steroid hormone stimulus GO:0071383 93 0.010
negative regulation of neuron projection development GO:0010977 46 0.010
sex differentiation GO:0007548 113 0.010
negative regulation of mitotic cell cycle phase transition GO:1901991 3 0.010
cell morphogenesis involved in neuron differentiation GO:0048667 106 0.010
epithelial cell proliferation GO:0050673 54 0.010
renin secretion into blood stream GO:0002001 1 0.010
negative regulation of neuron death GO:1901215 69 0.010
regulation of homeostatic process GO:0032844 101 0.010
heart development GO:0007507 72 0.010
response to amphetamine GO:0001975 25 0.010

Adrbk2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.016
musculoskeletal system disease DOID:17 0 0.016
central nervous system disease DOID:331 0 0.015
nervous system disease DOID:863 0 0.015
disease of cellular proliferation DOID:14566 0 0.010