Rattus norvegicus

0 known processes

Spast

spastin

(Aliases: Spg4)

Spast biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
regulation of cellular component organization GO:0051128 368 0.111
Zebrafish Fly
protein complex biogenesis GO:0070271 263 0.109
Human
organic substance catabolic process GO:1901575 316 0.102
Human Fly
nucleic acid templated transcription GO:0097659 379 0.101
regulation of molecular function GO:0065009 398 0.099
macromolecular complex assembly GO:0065003 273 0.087
Human
neuron projection development GO:0031175 273 0.075
Zebrafish Fly
positive regulation of cellular biosynthetic process GO:0031328 295 0.071
single organism catabolic process GO:0044712 283 0.064
Human Fly
positive regulation of multicellular organismal process GO:0051240 387 0.061
Zebrafish Fly
macromolecular complex subunit organization GO:0043933 339 0.058
Human Zebrafish Fly
cellular catabolic process GO:0044248 295 0.055
Human Fly
organelle organization GO:0006996 266 0.054
Human Zebrafish Fly
rna metabolic process GO:0016070 406 0.053
cellular component biogenesis GO:0044085 368 0.050
Human Fly
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.048
rna biosynthetic process GO:0032774 380 0.048
protein complex subunit organization GO:0071822 302 0.046
Human Zebrafish Fly
regulation of phosphorus metabolic process GO:0051174 349 0.045
carbohydrate metabolic process GO:0005975 130 0.045
regulation of cellular protein metabolic process GO:0032268 267 0.044
positive regulation of rna metabolic process GO:0051254 203 0.043
regulation of cellular localization GO:0060341 263 0.043
aromatic compound catabolic process GO:0019439 168 0.042
Human Fly
organophosphate biosynthetic process GO:0090407 143 0.041
regulation of catabolic process GO:0009894 113 0.041
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.040
carbohydrate derivative metabolic process GO:1901135 346 0.040
Human Fly
protein phosphorylation GO:0006468 345 0.038
regulation of protein metabolic process GO:0051246 289 0.038
carboxylic acid metabolic process GO:0019752 289 0.036
cellular component assembly GO:0022607 360 0.035
Human Fly
organic acid metabolic process GO:0006082 292 0.035
neuronal action potential GO:0019228 35 0.035
cellular ketone metabolic process GO:0042180 51 0.035
cellular amine metabolic process GO:0044106 38 0.034
amine metabolic process GO:0009308 38 0.034
response to growth factor GO:0070848 189 0.034
oxoacid metabolic process GO:0043436 290 0.033
positive regulation of biosynthetic process GO:0009891 319 0.033
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.033
intracellular signal transduction GO:0035556 314 0.033
positive regulation of rna biosynthetic process GO:1902680 197 0.032
regulation of cellular amino acid metabolic process GO:0006521 2 0.032
positive regulation of cellular component organization GO:0051130 200 0.031
Zebrafish Fly
cellular response to stress GO:0033554 269 0.031
regulation of cellular ketone metabolic process GO:0010565 27 0.030
transcription from rna polymerase ii promoter GO:0006366 252 0.030
positive regulation of transcription dna templated GO:0045893 197 0.030
protein localization GO:0008104 191 0.030
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.029
catabolic process GO:0009056 351 0.029
Human Fly
intracellular transport GO:0046907 185 0.029
Human
regulation of cellular component biogenesis GO:0044087 86 0.029
Fly
negative regulation of transport GO:0051051 136 0.029
single organism biosynthetic process GO:0044711 342 0.028
central nervous system development GO:0007417 311 0.028
Zebrafish
transcription dna templated GO:0006351 377 0.028
cellular protein localization GO:0034613 122 0.028
cell projection organization GO:0030030 302 0.028
Zebrafish Fly
cellular amino acid metabolic process GO:0006520 107 0.028
response to inorganic substance GO:0010035 377 0.027
regulation of cellular amine metabolic process GO:0033238 8 0.027
neuron development GO:0048666 286 0.027
Zebrafish Fly
regulation of phosphate metabolic process GO:0019220 349 0.027
purine containing compound metabolic process GO:0072521 253 0.027
Human Fly
regulation of apoptotic process GO:0042981 335 0.026
Zebrafish
positive regulation of transcription factor import into nucleus GO:0042993 4 0.026
defense response GO:0006952 194 0.026
protein complex assembly GO:0006461 263 0.026
Human
regulation of protein phosphorylation GO:0001932 183 0.026
regulation of transcription dna templated GO:0006355 374 0.026
regulation of nucleic acid templated transcription GO:1903506 380 0.025
cellular macromolecule localization GO:0070727 122 0.025
positive regulation of cell differentiation GO:0045597 217 0.024
Zebrafish Fly
positive regulation of phosphate metabolic process GO:0045937 262 0.024
neuron differentiation GO:0030182 368 0.024
Zebrafish Fly
positive regulation of developmental process GO:0051094 283 0.024
Zebrafish Fly
negative regulation of metabolic process GO:0009892 331 0.023
cellular response to growth factor stimulus GO:0071363 162 0.023
positive regulation of neurogenesis GO:0050769 165 0.023
Zebrafish Fly
positive regulation of cell projection organization GO:0031346 111 0.023
Zebrafish Fly
regulation of catalytic activity GO:0050790 304 0.023
regulation of nervous system development GO:0051960 264 0.023
Zebrafish Fly
anatomical structure morphogenesis GO:0009653 298 0.022
Zebrafish Fly
positive regulation of molecular function GO:0044093 230 0.022
regulation of phosphorylation GO:0042325 248 0.022
lymphocyte homeostasis GO:0002260 2 0.021
positive regulation of transport GO:0051050 245 0.021
positive regulation of gene expression GO:0010628 244 0.021
chemical homeostasis GO:0048878 292 0.021
nucleobase containing small molecule metabolic process GO:0055086 316 0.021
Human Fly
single organism intracellular transport GO:1902582 166 0.020
Human
regulation of neuron projection development GO:0010975 161 0.020
Zebrafish Fly
regulation of neuron differentiation GO:0045664 208 0.020
Zebrafish Fly
macromolecule localization GO:0033036 252 0.020
single organism reproductive process GO:0044702 297 0.019
negative regulation of macromolecule metabolic process GO:0010605 260 0.019
cell motility GO:0048870 202 0.019
Fly
cell migration GO:0016477 197 0.019
Fly
cellular component movement GO:0006928 248 0.018
Fly
ribonucleotide metabolic process GO:0009259 231 0.018
Human Fly
cellular response to endogenous stimulus GO:0071495 377 0.018
regulation of protein modification process GO:0031399 194 0.018
neurological system process GO:0050877 219 0.018
enzyme linked receptor protein signaling pathway GO:0007167 116 0.018
response to metal ion GO:0010038 253 0.018
cellular protein complex assembly GO:0043623 44 0.018
negative regulation of cell communication GO:0010648 158 0.017
Fly
organonitrogen compound biosynthetic process GO:1901566 167 0.017
vesicle mediated transport GO:0016192 181 0.017
Human
reproductive process GO:0022414 372 0.017
cytoskeleton organization GO:0007010 111 0.017
Human Zebrafish Fly
protein targeting to nucleus GO:0044744 35 0.017
regulation of neurogenesis GO:0050767 247 0.017
Zebrafish Fly
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.017
locomotion GO:0040011 237 0.017
Fly
purine nucleotide metabolic process GO:0006163 229 0.017
Human Fly
cellular nitrogen compound catabolic process GO:0044270 163 0.017
Human Fly
lipid metabolic process GO:0006629 283 0.017
cell morphogenesis GO:0000902 142 0.017
Zebrafish Fly
negative regulation of cell death GO:0060548 229 0.017
Zebrafish
single organism cellular localization GO:1902580 102 0.016
peptidyl amino acid modification GO:0018193 126 0.016
reproduction GO:0000003 245 0.016
single organism organelle organization GO:1902589 180 0.016
Human Zebrafish Fly
spindle organization GO:0007051 2 0.016
negative regulation of transcription from rna polymerase ii promoter GO:0000122 75 0.016
positive regulation of protein metabolic process GO:0051247 178 0.016
regulation of cell differentiation GO:0045595 320 0.016
Zebrafish Fly
localization of cell GO:0051674 202 0.016
Fly
ribose phosphate metabolic process GO:0019693 235 0.016
Human Fly
regulation of rna biosynthetic process GO:2001141 381 0.016
glycerolipid metabolic process GO:0046486 67 0.016
negative regulation of rna metabolic process GO:0051253 123 0.016
protein localization to organelle GO:0033365 57 0.016
multicellular organismal reproductive process GO:0048609 233 0.016
sister chromatid segregation GO:0000819 1 0.015
Fly
multi organism reproductive process GO:0044703 262 0.015
carbohydrate derivative catabolic process GO:1901136 147 0.015
Human Fly
protein transport GO:0015031 132 0.015
positive regulation of cellular component movement GO:0051272 102 0.015
positive regulation of nucleic acid templated transcription GO:1903508 197 0.015
negative regulation of gene expression GO:0010629 199 0.015
cell cell signaling GO:0007267 335 0.015
Fly
regulation of system process GO:0044057 208 0.015
homeostatic process GO:0042592 331 0.015
positive regulation of cell communication GO:0010647 271 0.014
Fly
positive regulation of cell development GO:0010720 176 0.014
Zebrafish Fly
positive regulation of phosphorus metabolic process GO:0010562 262 0.014
regulation of cell projection organization GO:0031344 175 0.014
Zebrafish Fly
positive regulation of response to stimulus GO:0048584 285 0.014
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.014
ncrna processing GO:0034470 3 0.014
nitrogen compound transport GO:0071705 229 0.014
regulation of response to stress GO:0080134 126 0.014
nucleotide metabolic process GO:0009117 279 0.014
Human Fly
nucleobase containing compound catabolic process GO:0034655 152 0.014
Human Fly
regulation of cellular catabolic process GO:0031329 101 0.014
dna metabolic process GO:0006259 96 0.014
regulation of cellular component movement GO:0051270 150 0.014
positive regulation of cellular amine metabolic process GO:0033240 3 0.014
single organism carbohydrate metabolic process GO:0044723 118 0.014
regulation of multicellular organismal development GO:2000026 376 0.013
Zebrafish Fly
behavioral response to ethanol GO:0048149 1 0.013
nucleoside phosphate catabolic process GO:1901292 140 0.013
Human Fly
positive regulation of neuron differentiation GO:0045666 126 0.013
Zebrafish Fly
cellular cation homeostasis GO:0030003 180 0.013
ras protein signal transduction GO:0007265 29 0.013
regulation of cell development GO:0060284 263 0.013
Zebrafish Fly
small gtpase mediated signal transduction GO:0007264 36 0.013
organophosphate metabolic process GO:0019637 370 0.013
Human Fly
action potential GO:0001508 54 0.013
ion homeostasis GO:0050801 212 0.013
microtubule based process GO:0007017 36 0.013
Human Zebrafish Mouse Fly
transmission of nerve impulse GO:0019226 42 0.012
organophosphate catabolic process GO:0046434 148 0.012
Human Fly
cation homeostasis GO:0055080 195 0.012
response to other organism GO:0051707 220 0.012
positive regulation of phosphorylation GO:0042327 177 0.012
gamete generation GO:0007276 124 0.012
rho protein signal transduction GO:0007266 11 0.012
negative regulation of signaling GO:0023057 157 0.012
Fly
regulation of cell motility GO:2000145 131 0.012
negative regulation of multicellular organismal process GO:0051241 203 0.012
Fly
regulation of membrane potential GO:0042391 110 0.012
regulation of signal transduction GO:0009966 318 0.012
axon cargo transport GO:0008088 1 0.012
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.012
cellular homeostasis GO:0019725 252 0.012
cellular chemical homeostasis GO:0055082 247 0.011
head development GO:0060322 247 0.011
response to peptide hormone GO:0043434 278 0.011
organic cyclic compound catabolic process GO:1901361 175 0.011
Human Fly
heterocycle catabolic process GO:0046700 167 0.011
Human Fly
response to radiation GO:0009314 137 0.011
positive regulation of cell migration GO:0030335 96 0.011
glycosyl compound metabolic process GO:1901657 182 0.011
Human Fly
response to corticosteroid GO:0031960 235 0.011
hormone secretion GO:0046879 115 0.011
nucleoside phosphate metabolic process GO:0006753 283 0.011
Human Fly
signal release GO:0023061 145 0.011
multicellular organism reproduction GO:0032504 233 0.011
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.011
purine nucleoside catabolic process GO:0006152 124 0.011
Human Fly
regulation of programmed cell death GO:0043067 341 0.010
Zebrafish
purine ribonucleotide metabolic process GO:0009150 227 0.010
Human Fly
positive regulation of nervous system development GO:0051962 178 0.010
Zebrafish Fly
axis specification GO:0009798 4 0.010
regulation of intracellular transport GO:0032386 65 0.010
anatomical structure formation involved in morphogenesis GO:0048646 83 0.010
negative regulation of molecular function GO:0044092 133 0.010

Spast disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org