Rattus norvegicus

0 known processes

Myl12b

myosin, light chain 12B, regulatory

(Aliases: Mrlc2,Mylc2b,Mrlcb)

Myl12b biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
nucleotide metabolic process GO:0009117 279 0.156
organophosphate metabolic process GO:0019637 370 0.134
single organism intracellular transport GO:1902582 166 0.130
Fly
purine containing compound catabolic process GO:0072523 138 0.128
cell motility GO:0048870 202 0.124
Fly
actin cytoskeleton organization GO:0030036 73 0.097
Fly
organonitrogen compound catabolic process GO:1901565 179 0.093
cellular component assembly GO:0022607 360 0.091
ribonucleoside triphosphate catabolic process GO:0009203 122 0.087
macromolecule localization GO:0033036 252 0.085
localization of cell GO:0051674 202 0.083
Fly
cellular component movement GO:0006928 248 0.082
Fly
cellular macromolecule localization GO:0070727 122 0.081
ribonucleotide metabolic process GO:0009259 231 0.080
intracellular transport GO:0046907 185 0.077
Fly
response to peptide GO:1901652 292 0.077
protein complex biogenesis GO:0070271 263 0.076
nucleoside phosphate metabolic process GO:0006753 283 0.075
protein transport GO:0015031 132 0.075
protein complex assembly GO:0006461 263 0.072
cellular component biogenesis GO:0044085 368 0.071
small gtpase mediated signal transduction GO:0007264 36 0.068
purine ribonucleoside triphosphate metabolic process GO:0009205 140 0.065
nitrogen compound transport GO:0071705 229 0.064
ribonucleotide catabolic process GO:0009261 136 0.064
cell migration GO:0016477 197 0.063
Fly
regulation of intracellular signal transduction GO:1902531 218 0.062
organelle organization GO:0006996 266 0.062
Fly
organic cyclic compound catabolic process GO:1901361 175 0.061
regulation of phosphate metabolic process GO:0019220 349 0.060
ribose phosphate metabolic process GO:0019693 235 0.060
vesicle mediated transport GO:0016192 181 0.060
nucleobase containing small molecule metabolic process GO:0055086 316 0.059
regulation of cellular localization GO:0060341 263 0.059
purine nucleoside catabolic process GO:0006152 124 0.058
protein phosphorylation GO:0006468 345 0.058
carboxylic acid metabolic process GO:0019752 289 0.057
cell cell signaling GO:0007267 335 0.057
regulation of cellular component movement GO:0051270 150 0.057
negative regulation of macromolecule metabolic process GO:0010605 260 0.056
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.056
regulation of signal transduction GO:0009966 318 0.056
purine ribonucleoside metabolic process GO:0046128 168 0.056
regulation of cellular component organization GO:0051128 368 0.056
Mouse Fly
macromolecular complex assembly GO:0065003 273 0.054
ribonucleoside catabolic process GO:0042454 126 0.054
nucleoside metabolic process GO:0009116 179 0.053
nucleoside triphosphate catabolic process GO:0009143 123 0.052
regulation of locomotion GO:0040012 148 0.052
purine containing compound metabolic process GO:0072521 253 0.051
protein localization GO:0008104 191 0.051
cellular response to stress GO:0033554 269 0.050
synaptic transmission GO:0007268 235 0.050
cellular protein localization GO:0034613 122 0.049
cellular nitrogen compound catabolic process GO:0044270 163 0.049
negative regulation of metabolic process GO:0009892 331 0.049
guanosine containing compound metabolic process GO:1901068 74 0.048
organophosphate catabolic process GO:0046434 148 0.048
nucleobase containing compound catabolic process GO:0034655 152 0.047
aromatic compound catabolic process GO:0019439 168 0.047
single organism cellular localization GO:1902580 102 0.047
nucleoside triphosphate metabolic process GO:0009141 144 0.047
regulation of cell development GO:0060284 263 0.046
ras protein signal transduction GO:0007265 29 0.046
positive regulation of response to stimulus GO:0048584 285 0.046
regulation of molecular function GO:0065009 398 0.045
cation transport GO:0006812 382 0.045
hormone secretion GO:0046879 115 0.045
heterocycle catabolic process GO:0046700 167 0.045
neuron projection development GO:0031175 273 0.044
positive regulation of cell communication GO:0010647 271 0.044
regulation of hormone levels GO:0010817 187 0.044
response to oxidative stress GO:0006979 186 0.043
positive regulation of cell proliferation GO:0008284 249 0.043
programmed cell death GO:0012501 392 0.043
cellular homeostasis GO:0019725 252 0.043
positive regulation of cellular component organization GO:0051130 200 0.042
response to metal ion GO:0010038 253 0.042
nucleoside phosphate catabolic process GO:1901292 140 0.042
regulation of nucleic acid templated transcription GO:1903506 380 0.041
reproductive process GO:0022414 372 0.041
Fly
protein targeting GO:0006605 61 0.041
cellular amine metabolic process GO:0044106 38 0.041
positive regulation of signaling GO:0023056 270 0.041
purine nucleoside metabolic process GO:0042278 169 0.041
immune system process GO:0002376 204 0.041
Rat
epithelium development GO:0060429 96 0.040
Fly
cytoplasmic transport GO:0016482 115 0.040
Fly
response to peptide hormone GO:0043434 278 0.040
positive regulation of transport GO:0051050 245 0.040
cellular response to oxygen containing compound GO:1901701 386 0.039
rna biosynthetic process GO:0032774 380 0.039
purine nucleoside triphosphate metabolic process GO:0009144 141 0.039
response to corticosteroid GO:0031960 235 0.038
carbohydrate derivative metabolic process GO:1901135 346 0.038
nucleic acid templated transcription GO:0097659 379 0.038
hormone transport GO:0009914 121 0.038
regulation of phosphorylation GO:0042325 248 0.038
macromolecular complex subunit organization GO:0043933 339 0.038
cellular response to organonitrogen compound GO:0071417 197 0.038
purine ribonucleotide metabolic process GO:0009150 227 0.037
cellular chemical homeostasis GO:0055082 247 0.037
protein complex subunit organization GO:0071822 302 0.037
cellular response to hormone stimulus GO:0032870 247 0.037
rna metabolic process GO:0016070 406 0.037
regulation of cell motility GO:2000145 131 0.037
positive regulation of phosphate metabolic process GO:0045937 262 0.036
nucleoside catabolic process GO:0009164 126 0.036
single organism catabolic process GO:0044712 283 0.036
transcription dna templated GO:0006351 377 0.036
catabolic process GO:0009056 351 0.036
positive regulation of developmental process GO:0051094 283 0.036
chemical homeostasis GO:0048878 292 0.036
negative regulation of cellular metabolic process GO:0031324 281 0.035
cellular catabolic process GO:0044248 295 0.035
response to decreased oxygen levels GO:0036293 237 0.035
actin filament based process GO:0030029 86 0.035
Fly
response to glucocorticoid GO:0051384 223 0.035
regulation of protein phosphorylation GO:0001932 183 0.034
positive regulation of intracellular signal transduction GO:1902533 138 0.034
positive regulation of molecular function GO:0044093 230 0.034
protein oligomerization GO:0051259 191 0.034
glycosyl compound metabolic process GO:1901657 182 0.034
intracellular protein transport GO:0006886 79 0.034
cellular lipid metabolic process GO:0044255 208 0.034
cellular ketone metabolic process GO:0042180 51 0.034
regulation of multicellular organismal development GO:2000026 376 0.033
signal release GO:0023061 145 0.033
intracellular signal transduction GO:0035556 314 0.033
positive regulation of multicellular organismal process GO:0051240 387 0.033
regulation of neurogenesis GO:0050767 247 0.033
cytoskeleton organization GO:0007010 111 0.032
Fly
membrane organization GO:0061024 94 0.032
regulation of nervous system development GO:0051960 264 0.032
regulation of rna metabolic process GO:0051252 391 0.032
regulation of phosphorus metabolic process GO:0051174 349 0.032
g protein coupled receptor signaling pathway GO:0007186 242 0.031
regulation of protein metabolic process GO:0051246 289 0.031
purine nucleotide catabolic process GO:0006195 136 0.031
carbohydrate derivative catabolic process GO:1901136 147 0.031
purine ribonucleoside triphosphate catabolic process GO:0009207 122 0.031
organic acid metabolic process GO:0006082 292 0.030
positive regulation of cell development GO:0010720 176 0.030
neuron differentiation GO:0030182 368 0.030
Fly
response to growth factor GO:0070848 189 0.030
endocytosis GO:0006897 84 0.029
regulation of programmed cell death GO:0043067 341 0.029
apoptotic process GO:0006915 381 0.029
regulation of cell morphogenesis GO:0022604 77 0.029
Mouse
positive regulation of phosphorus metabolic process GO:0010562 262 0.029
cellular response to endogenous stimulus GO:0071495 377 0.028
lipid metabolic process GO:0006629 283 0.028
purine ribonucleotide catabolic process GO:0009154 136 0.028
purine ribonucleoside catabolic process GO:0046130 124 0.028
regulation of ion transport GO:0043269 245 0.028
positive regulation of biosynthetic process GO:0009891 319 0.028
nucleotide catabolic process GO:0009166 139 0.028
regulation of catalytic activity GO:0050790 304 0.028
establishment of protein localization GO:0045184 141 0.028
cellular amino acid metabolic process GO:0006520 107 0.028
negative regulation of biosynthetic process GO:0009890 168 0.027
multicellular organismal reproductive process GO:0048609 233 0.027
Fly
single organism reproductive process GO:0044702 297 0.026
Fly
positive regulation of protein phosphorylation GO:0001934 135 0.026
immune response GO:0006955 104 0.026
Rat
amine metabolic process GO:0009308 38 0.026
positive regulation of cytosolic calcium ion concentration GO:0007204 122 0.026
secretion GO:0046903 307 0.026
cellular response to nitrogen compound GO:1901699 210 0.025
reproduction GO:0000003 245 0.025
Fly
glycosyl compound catabolic process GO:1901658 126 0.025
metal ion homeostasis GO:0055065 186 0.025
response to hypoxia GO:0001666 231 0.025
oxoacid metabolic process GO:0043436 290 0.025
divalent inorganic cation homeostasis GO:0072507 165 0.025
purine nucleotide metabolic process GO:0006163 229 0.025
ribonucleoside metabolic process GO:0009119 174 0.025
negative regulation of multicellular organismal process GO:0051241 203 0.025
regulation of transcription dna templated GO:0006355 374 0.024
regulation of cellular ketone metabolic process GO:0010565 27 0.024
regulation of apoptotic process GO:0042981 335 0.024
response to ethanol GO:0045471 162 0.024
positive regulation of cellular protein metabolic process GO:0032270 167 0.024
tissue development GO:0009888 252 0.023
Rat Fly
response to inorganic substance GO:0010035 377 0.023
regulation of system process GO:0044057 208 0.023
negative regulation of phosphate metabolic process GO:0045936 80 0.023
negative regulation of response to stimulus GO:0048585 155 0.023
dna metabolic process GO:0006259 96 0.023
positive regulation of cellular biosynthetic process GO:0031328 295 0.023
regulation of cellular amine metabolic process GO:0033238 8 0.023
regulation of cell proliferation GO:0042127 359 0.023
regulation of cell differentiation GO:0045595 320 0.023
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.022
cell morphogenesis involved in differentiation GO:0000904 119 0.022
Fly
behavior GO:0007610 205 0.022
regulation of cellular amino acid metabolic process GO:0006521 2 0.022
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.022
single organism organelle organization GO:1902589 180 0.022
Fly
homeostatic process GO:0042592 331 0.022
signal transduction by phosphorylation GO:0023014 144 0.022
anatomical structure morphogenesis GO:0009653 298 0.022
Mouse Fly
multi organism reproductive process GO:0044703 262 0.022
Fly
phospholipid metabolic process GO:0006644 61 0.022
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.022
gtp metabolic process GO:0046039 72 0.022
gtp catabolic process GO:0006184 71 0.022
positive regulation of cellular amine metabolic process GO:0033240 3 0.021
cytoskeleton dependent cytokinesis GO:0061640 2 0.021
Fly
regulation of anatomical structure size GO:0090066 135 0.021
Fly
regulation of protein localization GO:0032880 81 0.021
positive regulation of cell differentiation GO:0045597 217 0.021
locomotion GO:0040011 237 0.021
Fly
cellular calcium ion homeostasis GO:0006874 160 0.021
guanosine containing compound catabolic process GO:1901069 71 0.020
peptide transport GO:0015833 97 0.020
negative regulation of phosphorylation GO:0042326 57 0.020
mapk cascade GO:0000165 140 0.020
regulation of anatomical structure morphogenesis GO:0022603 141 0.020
Mouse
positive regulation of phosphorylation GO:0042327 177 0.020
transmembrane transport GO:0055085 412 0.020
response to oxygen levels GO:0070482 265 0.020
positive regulation of cell death GO:0010942 184 0.020
histamine secretion involved in inflammatory response GO:0002441 3 0.020
ion homeostasis GO:0050801 212 0.020
negative regulation of protein metabolic process GO:0051248 114 0.019
purine nucleoside triphosphate catabolic process GO:0009146 122 0.019
calcium ion homeostasis GO:0055074 162 0.019
ribonucleoside triphosphate metabolic process GO:0009199 141 0.019
cation homeostasis GO:0055080 195 0.019
regulation of response to stress GO:0080134 126 0.019
metal ion transport GO:0030001 289 0.019
response to cytokine GO:0034097 215 0.019
regulation of secretion GO:0051046 224 0.019
positive regulation of cell migration GO:0030335 96 0.019
response to carbohydrate GO:0009743 183 0.018
wound healing GO:0042060 122 0.018
Fly
cellular response to insulin stimulus GO:0032869 81 0.018
head development GO:0060322 247 0.018
response to acid chemical GO:0001101 222 0.018
cytosolic calcium ion homeostasis GO:0051480 140 0.018
regulation of cellular protein metabolic process GO:0032268 267 0.018
positive regulation of immune system process GO:0002684 90 0.018
axis specification GO:0009798 4 0.018
neuron development GO:0048666 286 0.018
regulation of immune system process GO:0002682 123 0.018
response to wounding GO:0009611 254 0.018
Fly
regulation of vesicle mediated transport GO:0060627 81 0.018
regulation of organelle organization GO:0033043 80 0.018
Fly
positive regulation of cell motility GO:2000147 97 0.017
positive regulation of protein modification process GO:0031401 142 0.017
muscle cell proliferation GO:0033002 84 0.017
amide transport GO:0042886 105 0.017
organic substance catabolic process GO:1901575 316 0.017
anterior posterior pattern specification GO:0009952 1 0.017
Fly
biological adhesion GO:0022610 110 0.017
regulation of neuron differentiation GO:0045664 208 0.017
protein localization to organelle GO:0033365 57 0.017
cellular cation homeostasis GO:0030003 180 0.017
regulation of mapk cascade GO:0043408 116 0.017
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.017
regulation of cell migration GO:0030334 128 0.017
peptide secretion GO:0002790 86 0.017
positive regulation of cellular component movement GO:0051272 102 0.016
positive regulation of gene expression GO:0010628 244 0.016
circulatory system development GO:0072359 134 0.016
protein localization to membrane GO:0072657 36 0.016
inflammatory response GO:0006954 150 0.016
positive regulation of programmed cell death GO:0043068 157 0.016
regulation of protein modification process GO:0031399 194 0.016
cell morphogenesis involved in neuron differentiation GO:0048667 106 0.016
cellular response to organic cyclic compound GO:0071407 202 0.016
negative regulation of cell death GO:0060548 229 0.016
negative regulation of gene expression GO:0010629 199 0.016
cell morphogenesis GO:0000902 142 0.016
Mouse Fly
adult locomotory behavior GO:0008344 4 0.016
regulation of embryonic development GO:0045995 2 0.016
growth GO:0040007 165 0.016
Fly
single organism membrane organization GO:0044802 74 0.016
cellular response to cytokine stimulus GO:0071345 127 0.016
negative regulation of cellular protein metabolic process GO:0032269 106 0.016
regulation of erk1 and erk2 cascade GO:0070372 41 0.016
muscle system process GO:0003012 115 0.016
sensory perception GO:0007600 101 0.016
regulation of smooth muscle cell proliferation GO:0048660 75 0.015
organelle localization GO:0051640 55 0.015
Fly
cell projection organization GO:0030030 302 0.015
Fly
tube development GO:0035295 89 0.015
Fly
response to estrogen GO:0043627 232 0.015
regulation of metal ion transport GO:0010959 118 0.015
cell junction maintenance GO:0034331 1 0.015
cell adhesion GO:0007155 110 0.015
central nervous system development GO:0007417 311 0.015
defense response GO:0006952 194 0.015
protein heterooligomerization GO:0051291 89 0.015
regulation of body fluid levels GO:0050878 90 0.015
regulation of cellular component biogenesis GO:0044087 86 0.015
rna localization GO:0006403 4 0.015
response to insulin GO:0032868 133 0.015
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.015
endomembrane system organization GO:0010256 48 0.014
negative regulation of cell proliferation GO:0008285 119 0.014
cellular metal ion homeostasis GO:0006875 172 0.014
leukocyte activation GO:0045321 76 0.014
ion transmembrane transport GO:0034220 365 0.014
embryonic pattern specification GO:0009880 1 0.014
response to nutrient levels GO:0031667 370 0.014
cell type specific apoptotic process GO:0097285 134 0.014
cell activation GO:0001775 97 0.014
monovalent inorganic cation transport GO:0015672 172 0.014
positive regulation of apoptotic process GO:0043065 154 0.014
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.014
synaptic growth at neuromuscular junction GO:0051124 1 0.014
response to bacterium GO:0009617 200 0.014
negative regulation of programmed cell death GO:0043069 183 0.013
establishment of protein localization to membrane GO:0090150 16 0.013
regulation of cell morphogenesis involved in differentiation GO:0010769 72 0.013
regulation of dna metabolic process GO:0051052 60 0.013
positive regulation of mapk cascade GO:0043410 92 0.013
cellular ion homeostasis GO:0006873 184 0.013
regulation of secretion by cell GO:1903530 208 0.013
cellular component morphogenesis GO:0032989 155 0.013
Mouse Fly
regulation of nucleotide metabolic process GO:0006140 117 0.013
negative regulation of molecular function GO:0044092 133 0.013
brain development GO:0007420 247 0.013
regulation of hormone secretion GO:0046883 106 0.013
organophosphate biosynthetic process GO:0090407 143 0.013
positive regulation of catalytic activity GO:0043085 184 0.013
negative regulation of transport GO:0051051 136 0.013
morphogenesis of embryonic epithelium GO:0016331 3 0.013
spermatogenesis GO:0007283 99 0.013
divalent metal ion transport GO:0070838 132 0.013
negative regulation of signaling GO:0023057 157 0.013
regulation of protein transport GO:0051223 68 0.013
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.013
sexual reproduction GO:0019953 148 0.013
Fly
regulation of establishment of protein localization GO:0070201 69 0.013
negative regulation of cellular biosynthetic process GO:0031327 161 0.013
regulation of neuron projection development GO:0010975 161 0.013
nucleoside monophosphate metabolic process GO:0009123 93 0.012
negative regulation of phosphorus metabolic process GO:0010563 80 0.012
somatic stem cell division GO:0048103 2 0.012
neurological system process GO:0050877 219 0.012
secretion by cell GO:0032940 248 0.012
multicellular organism reproduction GO:0032504 233 0.012
Fly
divalent inorganic cation transport GO:0072511 134 0.012
axon development GO:0061564 96 0.012
regulation of neuron death GO:1901214 115 0.012
negative regulation of catalytic activity GO:0043086 103 0.012
glutamate receptor signaling pathway GO:0007215 43 0.012
negative regulation of nucleic acid templated transcription GO:1903507 117 0.012
response to radiation GO:0009314 137 0.012
calcium ion transport GO:0006816 131 0.012
stem cell division GO:0017145 4 0.012
smooth muscle cell proliferation GO:0048659 77 0.012
embryo development GO:0009790 49 0.012
Fly
angiogenesis GO:0001525 53 0.012
regulation of response to wounding GO:1903034 69 0.012
regulation of transferase activity GO:0051338 123 0.012
positive regulation of nervous system development GO:0051962 178 0.012
response to monosaccharide GO:0034284 159 0.012
cellular response to hydroperoxide GO:0071447 2 0.012
regulation of synaptic transmission GO:0050804 141 0.012
positive regulation of protein metabolic process GO:0051247 178 0.012
negative regulation of apoptotic process GO:0043066 181 0.012
reactive oxygen species metabolic process GO:0072593 37 0.012
icosanoid metabolic process GO:0006690 38 0.011
regulation of cell projection organization GO:0031344 175 0.011
regulation of cell maturation GO:1903429 3 0.011
regulation of intracellular protein transport GO:0033157 34 0.011
response to calcium ion GO:0051592 59 0.011
regulation of muscle system process GO:0090257 79 0.011
atp metabolic process GO:0046034 72 0.011
cellular macromolecular complex assembly GO:0034622 58 0.011
positive regulation of reactive oxygen species biosynthetic process GO:1903428 2 0.011
neuron death GO:0070997 127 0.011
regulation of rna biosynthetic process GO:2001141 381 0.011
response to hydrogen peroxide GO:0042542 89 0.011
purine nucleoside monophosphate metabolic process GO:0009126 84 0.011
positive regulation of neurogenesis GO:0050769 165 0.011
positive regulation of reactive oxygen species metabolic process GO:2000379 16 0.011
cellular divalent inorganic cation homeostasis GO:0072503 162 0.011
cellular response to peptide hormone stimulus GO:0071375 120 0.011
asymmetric stem cell division GO:0098722 2 0.011
actin cytoskeleton reorganization GO:0031532 8 0.011
response to biotic stimulus GO:0009607 226 0.011
detection of visible light GO:0009584 3 0.011
male gamete generation GO:0048232 99 0.011
negative regulation of rna metabolic process GO:0051253 123 0.011
cell cycle process GO:0022402 57 0.011
Fly
response to other organism GO:0051707 220 0.011
ribonucleoside monophosphate metabolic process GO:0009161 88 0.010
single organism biosynthetic process GO:0044711 342 0.010
cortical actin cytoskeleton organization GO:0030866 2 0.010
negative regulation of mitotic cell cycle phase transition GO:1901991 3 0.010
peptide hormone secretion GO:0030072 84 0.010
positive regulation of rna metabolic process GO:0051254 203 0.010
reactive nitrogen species metabolic process GO:2001057 1 0.010
positive regulation of transferase activity GO:0051347 81 0.010
regulation of kinase activity GO:0043549 117 0.010
immune effector process GO:0002252 53 0.010
exocytosis GO:0006887 60 0.010

Myl12b disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.019
nervous system disease DOID:863 0 0.019
central nervous system disease DOID:331 0 0.010