Rattus norvegicus

0 known processes

Pde8a

phosphodiesterase 8A

(Aliases: RNPDE8A)

Pde8a biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
carboxylic acid metabolic process GO:0019752 289 0.070
response to nutrient levels GO:0031667 370 0.049
response to extracellular stimulus GO:0009991 380 0.047
organic acid metabolic process GO:0006082 292 0.045
programmed cell death GO:0012501 392 0.041
amine metabolic process GO:0009308 38 0.041
transcription dna templated GO:0006351 377 0.039
oxoacid metabolic process GO:0043436 290 0.039
lipid metabolic process GO:0006629 283 0.039
negative regulation of macromolecule metabolic process GO:0010605 260 0.038
catabolic process GO:0009056 351 0.035
Rat
response to nutrient GO:0007584 248 0.035
regulation of molecular function GO:0065009 398 0.033
cellular catabolic process GO:0044248 295 0.033
Rat
cellular ketone metabolic process GO:0042180 51 0.033
regulation of cellular ketone metabolic process GO:0010565 27 0.032
single organism biosynthetic process GO:0044711 342 0.032
cellular amine metabolic process GO:0044106 38 0.032
regulation of cellular amino acid metabolic process GO:0006521 2 0.032
cellular amino acid metabolic process GO:0006520 107 0.031
cellular lipid metabolic process GO:0044255 208 0.031
nucleobase containing small molecule metabolic process GO:0055086 316 0.030
Rat
regulation of programmed cell death GO:0043067 341 0.030
regulation of cellular localization GO:0060341 263 0.030
Rat
intracellular signal transduction GO:0035556 314 0.029
Rat
secretion GO:0046903 307 0.029
Rat
negative regulation of metabolic process GO:0009892 331 0.028
eye morphogenesis GO:0048592 4 0.028
reproductive process GO:0022414 372 0.028
secretion by cell GO:0032940 248 0.028
Rat
homeostatic process GO:0042592 331 0.028
macromolecular complex assembly GO:0065003 273 0.027
regulation of secretion by cell GO:1903530 208 0.027
Rat
regulation of cellular amine metabolic process GO:0033238 8 0.027
rna metabolic process GO:0016070 406 0.027
cellular response to endogenous stimulus GO:0071495 377 0.026
tissue development GO:0009888 252 0.026
Fly
protein complex biogenesis GO:0070271 263 0.026
apoptotic process GO:0006915 381 0.026
regulation of rna biosynthetic process GO:2001141 381 0.025
neuron development GO:0048666 286 0.025
negative regulation of multicellular organismal process GO:0051241 203 0.025
neuron differentiation GO:0030182 368 0.025
regulation of transcription dna templated GO:0006355 374 0.025
protein complex assembly GO:0006461 263 0.024
negative regulation of cellular metabolic process GO:0031324 281 0.024
response to inorganic substance GO:0010035 377 0.024
Rat
positive regulation of multicellular organismal process GO:0051240 387 0.024
carbohydrate derivative metabolic process GO:1901135 346 0.024
Rat
cellular component assembly GO:0022607 360 0.024
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.023
central nervous system development GO:0007417 311 0.023
single organism catabolic process GO:0044712 283 0.023
Rat
regulation of apoptotic process GO:0042981 335 0.023
cellular homeostasis GO:0019725 252 0.023
macromolecular complex subunit organization GO:0043933 339 0.023
nucleic acid templated transcription GO:0097659 379 0.023
transcription from rna polymerase ii promoter GO:0006366 252 0.023
multicellular organism growth GO:0035264 1 0.023
cellular response to stress GO:0033554 269 0.023
cellular component biogenesis GO:0044085 368 0.023
protein oligomerization GO:0051259 191 0.022
multicellular organismal reproductive process GO:0048609 233 0.022
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.022
regulation of phosphate metabolic process GO:0019220 349 0.022
regulation of cell development GO:0060284 263 0.022
organophosphate metabolic process GO:0019637 370 0.022
Rat
protein complex subunit organization GO:0071822 302 0.022
aging GO:0007568 241 0.022
ion homeostasis GO:0050801 212 0.022
brain development GO:0007420 247 0.021
multi organism reproductive process GO:0044703 262 0.021
positive regulation of nucleic acid templated transcription GO:1903508 197 0.021
cell cell signaling GO:0007267 335 0.021
Rat
regulation of cellular component organization GO:0051128 368 0.021
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.021
protein phosphorylation GO:0006468 345 0.021
cation transport GO:0006812 382 0.021
chemical homeostasis GO:0048878 292 0.021
response to estrogen GO:0043627 232 0.020
fatty acid metabolic process GO:0006631 99 0.020
organic hydroxy compound metabolic process GO:1901615 115 0.020
neurological system process GO:0050877 219 0.020
Rat
positive regulation of cell differentiation GO:0045597 217 0.020
anion transport GO:0006820 178 0.020
cellular response to oxygen containing compound GO:1901701 386 0.019
regulation of protein metabolic process GO:0051246 289 0.019
response to decreased oxygen levels GO:0036293 237 0.019
regulation of rna metabolic process GO:0051252 391 0.019
multicellular organism reproduction GO:0032504 233 0.019
lipid biosynthetic process GO:0008610 128 0.019
regulation of secretion GO:0051046 224 0.019
Rat
axis specification GO:0009798 4 0.019
response to peptide hormone GO:0043434 278 0.019
nucleoside phosphate metabolic process GO:0006753 283 0.019
Rat
purine ribonucleotide metabolic process GO:0009150 227 0.019
Rat
negative regulation of cell death GO:0060548 229 0.019
purine containing compound metabolic process GO:0072521 253 0.019
Rat
regulation of phosphorus metabolic process GO:0051174 349 0.019
negative regulation of programmed cell death GO:0043069 183 0.019
positive regulation of biosynthetic process GO:0009891 319 0.019
regulation of multicellular organismal development GO:2000026 376 0.019
regulation of protein modification process GO:0031399 194 0.018
cellular ion homeostasis GO:0006873 184 0.018
cellular response to nitrogen compound GO:1901699 210 0.018
regulation of cell differentiation GO:0045595 320 0.018
head development GO:0060322 247 0.018
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.018
regulation of nucleic acid templated transcription GO:1903506 380 0.018
positive regulation of developmental process GO:0051094 283 0.018
transmembrane transport GO:0055085 412 0.018
negative regulation of molecular function GO:0044092 133 0.018
regulation of nervous system development GO:0051960 264 0.018
cation homeostasis GO:0055080 195 0.018
positive regulation of cell development GO:0010720 176 0.017
circadian rhythm GO:0007623 88 0.017
reproduction GO:0000003 245 0.017
regulation of intracellular signal transduction GO:1902531 218 0.017
cell projection organization GO:0030030 302 0.017
regulation of signal transduction GO:0009966 318 0.017
positive regulation of cell death GO:0010942 184 0.017
response to metal ion GO:0010038 253 0.017
Rat
positive regulation of cellular amine metabolic process GO:0033240 3 0.017
positive regulation of transcription dna templated GO:0045893 197 0.017
response to hypoxia GO:0001666 231 0.017
circulatory system process GO:0003013 183 0.017
rhythmic process GO:0048511 156 0.017
proteolysis GO:0006508 175 0.016
nucleotide metabolic process GO:0009117 279 0.016
Rat
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.016
cellular chemical homeostasis GO:0055082 247 0.016
cellular response to peptide GO:1901653 133 0.016
heart morphogenesis GO:0003007 3 0.016
cellular response to organic cyclic compound GO:0071407 202 0.016
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.016
cellular response to growth factor stimulus GO:0071363 162 0.016
positive regulation of nervous system development GO:0051962 178 0.016
response to peptide GO:1901652 292 0.016
cellular cation homeostasis GO:0030003 180 0.016
defense response GO:0006952 194 0.016
cellular response to organonitrogen compound GO:0071417 197 0.016
neuron projection development GO:0031175 273 0.016
single organism reproductive process GO:0044702 297 0.015
positive regulation of molecular function GO:0044093 230 0.015
response to oxygen levels GO:0070482 265 0.015
nitrogen compound transport GO:0071705 229 0.015
Rat
response to oxidative stress GO:0006979 186 0.015
organonitrogen compound biosynthetic process GO:1901566 167 0.015
negative regulation of transport GO:0051051 136 0.015
Rat
regulation of anatomical structure size GO:0090066 135 0.015
regulation of protein phosphorylation GO:0001932 183 0.015
regulation of catalytic activity GO:0050790 304 0.015
negative regulation of signaling GO:0023057 157 0.015
Rat
response to biotic stimulus GO:0009607 226 0.015
organic substance catabolic process GO:1901575 316 0.015
Rat
rna biosynthetic process GO:0032774 380 0.015
positive regulation of signaling GO:0023056 270 0.015
positive regulation of neurogenesis GO:0050769 165 0.015
regulation of neurogenesis GO:0050767 247 0.014
metal ion transport GO:0030001 289 0.014
response to transition metal nanoparticle GO:1990267 122 0.014
positive regulation of cell communication GO:0010647 271 0.014
regulation of hormone levels GO:0010817 187 0.014
Rat
neuron death GO:0070997 127 0.014
response to acid chemical GO:0001101 222 0.014
behavior GO:0007610 205 0.014
organonitrogen compound catabolic process GO:1901565 179 0.014
Rat
positive regulation of cell projection organization GO:0031346 111 0.014
dna metabolic process GO:0006259 96 0.014
dephosphorylation GO:0016311 98 0.014
positive regulation of cellular biosynthetic process GO:0031328 295 0.014
mesoderm development GO:0007498 2 0.014
Fly
positive regulation of rna metabolic process GO:0051254 203 0.014
positive regulation of neuron differentiation GO:0045666 126 0.014
regulation of hydrolase activity GO:0051336 143 0.014
inorganic ion transmembrane transport GO:0098660 229 0.014
monocarboxylic acid metabolic process GO:0032787 152 0.014
regulation of system process GO:0044057 208 0.014
positive regulation of transport GO:0051050 245 0.014
regulation of neuron differentiation GO:0045664 208 0.014
regulation of cellular protein metabolic process GO:0032268 267 0.014
regulation of membrane potential GO:0042391 110 0.014
response to external biotic stimulus GO:0043207 221 0.014
chromosome segregation GO:0007059 2 0.014
response to ethanol GO:0045471 162 0.013
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.013
cellular divalent inorganic cation homeostasis GO:0072503 162 0.013
sensory perception GO:0007600 101 0.013
Rat
response to alkaloid GO:0043279 132 0.013
negative regulation of protein metabolic process GO:0051248 114 0.013
ion transmembrane transport GO:0034220 365 0.013
regulation of cell proliferation GO:0042127 359 0.013
heterocycle catabolic process GO:0046700 167 0.013
Rat
positive regulation of response to stimulus GO:0048584 285 0.013
response to estradiol GO:0032355 164 0.013
blood circulation GO:0008015 183 0.013
response to cytokine GO:0034097 215 0.013
negative regulation of apoptotic process GO:0043066 181 0.013
alcohol metabolic process GO:0006066 77 0.013
inorganic cation transmembrane transport GO:0098662 202 0.013
divalent inorganic cation homeostasis GO:0072507 165 0.013
response to bacterium GO:0009617 200 0.013
monovalent inorganic cation transport GO:0015672 172 0.013
negative regulation of cell communication GO:0010648 158 0.013
Rat
negative regulation of gene expression GO:0010629 199 0.013
regulation of hormone secretion GO:0046883 106 0.012
Rat
embryonic pattern specification GO:0009880 1 0.012
protein heterooligomerization GO:0051291 89 0.012
positive regulation of neuron projection development GO:0010976 99 0.012
metal ion homeostasis GO:0055065 186 0.012
regulation of neuron projection development GO:0010975 161 0.012
response to purine containing compound GO:0014074 126 0.012
protein autophosphorylation GO:0046777 66 0.012
sensory organ development GO:0007423 74 0.012
developmental process involved in reproduction GO:0003006 159 0.012
positive regulation of rna biosynthetic process GO:1902680 197 0.012
purine nucleotide metabolic process GO:0006163 229 0.012
Rat
synaptic transmission GO:0007268 235 0.012
response to glucose GO:0009749 136 0.012
positive regulation of phosphorylation GO:0042327 177 0.012
anion transmembrane transport GO:0098656 77 0.012
hormone transport GO:0009914 121 0.012
Rat
anterior posterior pattern specification GO:0009952 1 0.012
ribose phosphate metabolic process GO:0019693 235 0.012
Rat
positive regulation of signal transduction GO:0009967 175 0.012
membrane organization GO:0061024 94 0.012
anatomical structure morphogenesis GO:0009653 298 0.012
positive regulation of apoptotic process GO:0043065 154 0.012
small molecule biosynthetic process GO:0044283 124 0.012
signal release GO:0023061 145 0.012
Rat
vesicle mediated transport GO:0016192 181 0.012
calcium ion homeostasis GO:0055074 162 0.012
cellular metal ion homeostasis GO:0006875 172 0.012
aromatic compound catabolic process GO:0019439 168 0.012
Rat
positive regulation of programmed cell death GO:0043068 157 0.012
hepaticobiliary system development GO:0061008 90 0.011
regulation of kinase activity GO:0043549 117 0.011
positive regulation of protein modification process GO:0031401 142 0.011
regulation of cell projection organization GO:0031344 175 0.011
mechanoreceptor differentiation GO:0042490 2 0.011
gastrulation GO:0007369 2 0.011
ras protein signal transduction GO:0007265 29 0.011
positive regulation of phosphorus metabolic process GO:0010562 262 0.011
negative regulation of catalytic activity GO:0043086 103 0.011
negative regulation of cellular biosynthetic process GO:0031327 161 0.011
positive regulation of gene expression GO:0010628 244 0.011
intracellular transport GO:0046907 185 0.011
response to growth factor GO:0070848 189 0.011
peptidyl amino acid modification GO:0018193 126 0.011
regulation of canonical wnt signaling pathway GO:0060828 4 0.011
macromolecule localization GO:0033036 252 0.011
response to carbohydrate GO:0009743 183 0.011
cellular response to peptide hormone stimulus GO:0071375 120 0.011
positive regulation of cellular component organization GO:0051130 200 0.011
heart development GO:0007507 72 0.011
nucleoside metabolic process GO:0009116 179 0.011
protein localization GO:0008104 191 0.011
positive regulation of secretion GO:0051047 140 0.011
ribonucleotide metabolic process GO:0009259 231 0.011
Rat
response to other organism GO:0051707 220 0.011
cytosolic calcium ion homeostasis GO:0051480 140 0.011
sexual reproduction GO:0019953 148 0.011
amide transport GO:0042886 105 0.011
Rat
positive regulation of cellular protein metabolic process GO:0032270 167 0.011
response to monosaccharide GO:0034284 159 0.011
negative regulation of biosynthetic process GO:0009890 168 0.011
organophosphate catabolic process GO:0046434 148 0.010
Rat
lipid storage GO:0019915 1 0.010
response to hexose GO:0009746 144 0.010
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.010
positive regulation of catalytic activity GO:0043085 184 0.010
organic anion transport GO:0015711 132 0.010
camera type eye development GO:0043010 48 0.010
defense response to gram negative bacterium GO:0050829 3 0.010
cellular response to cytokine stimulus GO:0071345 127 0.010
regulation of peptide transport GO:0090087 87 0.010
Rat

Pde8a disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.044
nervous system disease DOID:863 0 0.044
sensory system disease DOID:0050155 0 0.022
eye and adnexa disease DOID:1492 0 0.022
eye disease DOID:5614 0 0.022
disease of metabolism DOID:0014667 0 0.017
inherited metabolic disorder DOID:655 0 0.014
central nervous system disease DOID:331 0 0.014
disease of cellular proliferation DOID:14566 0 0.013
cancer DOID:162 0 0.011
retinal disease DOID:5679 0 0.011
organ system cancer DOID:0050686 0 0.011
cardiovascular system disease DOID:1287 0 0.010