Rattus norvegicus

67 known processes

Slco1b3

solute carrier organic anion transporter family, member 1b3

(Aliases: Oatp4,Slc21a10,Slco1b2,OATP-4,rlst-1)

Slco1b3 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
response to cesium ion GO:0010164 2 0.291
carboxylic acid metabolic process GO:0019752 289 0.206
Rat
response to biotic stimulus GO:0009607 226 0.192
chlorinated hydrocarbon metabolic process GO:0042196 4 0.172
oxoacid metabolic process GO:0043436 290 0.166
Rat
lipid metabolic process GO:0006629 283 0.164
fatty acid metabolic process GO:0006631 99 0.147
drug metabolic process GO:0017144 11 0.136
acyl coa metabolic process GO:0006637 28 0.119
naphthalene metabolic process GO:0018931 2 0.114
response to external biotic stimulus GO:0043207 221 0.109
organic acid metabolic process GO:0006082 292 0.103
Rat
naphthalene containing compound metabolic process GO:0090420 2 0.090
response to nutrient levels GO:0031667 370 0.089
monocarboxylic acid metabolic process GO:0032787 152 0.088
cellular amino acid metabolic process GO:0006520 107 0.081
Rat
single organism catabolic process GO:0044712 283 0.080
cellular catabolic process GO:0044248 295 0.075
regulation of serine type endopeptidase activity GO:1900003 1 0.074
small molecule catabolic process GO:0044282 59 0.072
regulation of protein metabolic process GO:0051246 289 0.070
carboxylic acid transport GO:0046942 115 0.066
oxidation reduction process GO:0055114 304 0.065
lipid biosynthetic process GO:0008610 128 0.064
response to other organism GO:0051707 220 0.061
organic substance catabolic process GO:1901575 316 0.061
anion transport GO:0006820 178 0.061
positive regulation of molecular function GO:0044093 230 0.060
response to extracellular stimulus GO:0009991 380 0.059
lipid localization GO:0010876 62 0.058
regulation of multicellular organismal development GO:2000026 376 0.057
regulation of cell development GO:0060284 263 0.057
linoleic acid metabolic process GO:0043651 4 0.053
protein complex biogenesis GO:0070271 263 0.052
female pregnancy GO:0007565 122 0.052
negative regulation of serine type endopeptidase activity GO:1900004 1 0.051
negative regulation of serine type peptidase activity GO:1902572 1 0.051
catabolic process GO:0009056 351 0.050
macromolecule localization GO:0033036 252 0.050
positive regulation of multicellular organismal process GO:0051240 387 0.050
halogenated hydrocarbon metabolic process GO:0042197 4 0.049
exogenous drug catabolic process GO:0042738 1 0.049
macromolecular complex subunit organization GO:0043933 339 0.047
response to nutrient GO:0007584 248 0.047
macromolecular complex assembly GO:0065003 273 0.047
positive regulation of nervous system development GO:0051962 178 0.047
secretion by cell GO:0032940 248 0.047
regulation of cellular ketone metabolic process GO:0010565 27 0.046
negative regulation of cellular metabolic process GO:0031324 281 0.045
response to ketone GO:1901654 182 0.044
jak stat cascade GO:0007259 26 0.044
cellular component assembly GO:0022607 360 0.044
regulation of hormone levels GO:0010817 187 0.043
Rat
regulation of nervous system development GO:0051960 264 0.042
chemical homeostasis GO:0048878 292 0.042
protein phosphorylation GO:0006468 345 0.042
alkaloid metabolic process GO:0009820 3 0.042
response to hypoxia GO:0001666 231 0.042
nicotine metabolic process GO:0018933 1 0.041
organic hydroxy compound metabolic process GO:1901615 115 0.041
Rat
negative regulation of metabolic process GO:0009892 331 0.040
lipid transport GO:0006869 61 0.039
regulation of neurogenesis GO:0050767 247 0.039
cellular lipid metabolic process GO:0044255 208 0.039
4 nitrophenol metabolic process GO:0018960 1 0.039
thioester metabolic process GO:0035383 28 0.039
response to decreased oxygen levels GO:0036293 237 0.038
reactive nitrogen species metabolic process GO:2001057 1 0.037
cellular response to stress GO:0033554 269 0.037
cellular amine metabolic process GO:0044106 38 0.037
lipid catabolic process GO:0016042 46 0.036
regulation of cell differentiation GO:0045595 320 0.036
establishment or maintenance of transmembrane electrochemical gradient GO:0010248 1 0.036
sterol homeostasis GO:0055092 3 0.035
response to oxygen levels GO:0070482 265 0.035
liver development GO:0001889 90 0.035
positive regulation of programmed cell death GO:0043068 157 0.035
glutathione transport GO:0034635 2 0.034
sodium independent organic anion transport GO:0043252 2 0.034
response to lipopolysaccharide GO:0032496 191 0.034
cellular component biogenesis GO:0044085 368 0.034
regulation of gluconeogenesis GO:0006111 4 0.034
response to peptide hormone GO:0043434 278 0.033
store operated calcium entry GO:0002115 2 0.033
regulation of serine type peptidase activity GO:1902571 1 0.033
negative regulation of cell differentiation GO:0045596 99 0.033
cellular carbohydrate metabolic process GO:0044262 72 0.033
sulfur compound metabolic process GO:0006790 70 0.032
reproductive structure development GO:0048608 128 0.032
amine metabolic process GO:0009308 38 0.031
regulation of cellular localization GO:0060341 263 0.031
organic acid catabolic process GO:0016054 49 0.031
organic acid transport GO:0015849 116 0.031
protein complex assembly GO:0006461 263 0.030
regulation of cell projection organization GO:0031344 175 0.030
regulation of neuron projection development GO:0010975 161 0.030
long chain fatty acid metabolic process GO:0001676 32 0.030
regulation of molecular function GO:0065009 398 0.030
lauric acid metabolic process GO:0048252 4 0.029
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.029
regulation of neuron differentiation GO:0045664 208 0.029
toxin catabolic process GO:0009407 1 0.028
chemosensory behavior GO:0007635 2 0.028
sorbitol biosynthetic process GO:0006061 1 0.028
retinal metabolic process GO:0042574 3 0.028
calcitriol biosynthetic process from calciol GO:0036378 2 0.027
response to vitamin GO:0033273 131 0.027
positive regulation of neurogenesis GO:0050769 165 0.027
trichloroethylene metabolic process GO:0018979 1 0.027
cellular lipid catabolic process GO:0044242 37 0.027
protein homooligomerization GO:0051260 91 0.027
hormone metabolic process GO:0042445 69 0.027
Rat
cellular ketone metabolic process GO:0042180 51 0.027
growth GO:0040007 165 0.027
regulation of cell proliferation GO:0042127 359 0.026
steroid metabolic process GO:0008202 73 0.026
regulation of cellular protein metabolic process GO:0032268 267 0.026
positive regulation of developmental process GO:0051094 283 0.026
acute inflammatory response GO:0002526 58 0.025
negative regulation of cell proliferation GO:0008285 119 0.025
negative regulation of cellular biosynthetic process GO:0031327 161 0.025
response to peptide GO:1901652 292 0.025
carboxylic acid catabolic process GO:0046395 49 0.025
response to food GO:0032094 27 0.025
single organism biosynthetic process GO:0044711 342 0.025
transmembrane transport GO:0055085 412 0.025
artery smooth muscle contraction GO:0014824 4 0.024
regulation of cellular amino acid metabolic process GO:0006521 2 0.024
olfactory learning GO:0008355 1 0.024
negative regulation of developmental process GO:0051093 125 0.024
olfactory behavior GO:0042048 2 0.024
gland development GO:0048732 155 0.024
hepaticobiliary system development GO:0061008 90 0.024
behavior GO:0007610 205 0.024
response to xenobiotic stimulus GO:0009410 23 0.023
positive regulation of cellular biosynthetic process GO:0031328 295 0.023
regulation of phosphorylation GO:0042325 248 0.023
fluorene metabolic process GO:0018917 1 0.023
multi organism reproductive process GO:0044703 262 0.022
response to bacterium GO:0009617 200 0.022
carboxylic acid biosynthetic process GO:0046394 83 0.022
reproductive process GO:0022414 372 0.022
cellular chemical homeostasis GO:0055082 247 0.022
positive regulation of protein kinase activity GO:0045860 73 0.022
positive regulation of protein metabolic process GO:0051247 178 0.022
protein complex subunit organization GO:0071822 302 0.022
organic acid biosynthetic process GO:0016053 83 0.022
vesicle mediated transport GO:0016192 181 0.022
drug catabolic process GO:0042737 1 0.022
protein oligomerization GO:0051259 191 0.022
regulation of cellular amine metabolic process GO:0033238 8 0.022
regulation of transcription dna templated GO:0006355 374 0.021
positive regulation of phosphorylation GO:0042327 177 0.021
response to chromate GO:0046687 3 0.021
hormone biosynthetic process GO:0042446 25 0.021
secretion GO:0046903 307 0.021
antibiotic transport GO:0042891 2 0.021
regulation of intracellular signal transduction GO:1902531 218 0.020
response to corticosteroid GO:0031960 235 0.020
regulation of protein kinase activity GO:0045859 105 0.020
acylglycerol metabolic process GO:0006639 21 0.020
neuron development GO:0048666 286 0.020
lipid storage GO:0019915 1 0.020
intracellular transport GO:0046907 185 0.020
epoxygenase p450 pathway GO:0019373 1 0.019
response to metal ion GO:0010038 253 0.019
fatty acid derivative metabolic process GO:1901568 38 0.019
positive regulation of transport GO:0051050 245 0.019
response to glucocorticoid GO:0051384 223 0.019
icosanoid metabolic process GO:0006690 38 0.019
establishment of protein localization GO:0045184 141 0.019
regulation of secretion by cell GO:1903530 208 0.019
sorbitol metabolic process GO:0006060 1 0.019
single organism intracellular transport GO:1902582 166 0.019
developmental process involved in reproduction GO:0003006 159 0.019
cellular response to reactive oxygen species GO:0034614 55 0.019
steroid biosynthetic process GO:0006694 48 0.018
regulation of catalytic activity GO:0050790 304 0.018
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.018
organonitrogen compound catabolic process GO:1901565 179 0.018
benzene containing compound metabolic process GO:0042537 22 0.018
multicellular organism growth GO:0035264 1 0.018
organic cyclic compound catabolic process GO:1901361 175 0.018
regulation of reactive oxygen species biosynthetic process GO:1903426 5 0.018
reactive oxygen species biosynthetic process GO:1903409 8 0.018
extracellular matrix constituent secretion GO:0070278 4 0.018
circadian rhythm GO:0007623 88 0.017
response to temperature stimulus GO:0009266 94 0.017
regulation of cellular component organization GO:0051128 368 0.017
alpha amino acid metabolic process GO:1901605 71 0.017
head development GO:0060322 247 0.017
regulation of protein modification process GO:0031399 194 0.017
lipid oxidation GO:0034440 30 0.017
negative regulation of macromolecule metabolic process GO:0010605 260 0.017
negative regulation of catalytic activity GO:0043086 103 0.017
response to cadmium ion GO:0046686 35 0.017
reactive oxygen species metabolic process GO:0072593 37 0.017
positive regulation of intracellular signal transduction GO:1902533 138 0.017
ion transmembrane transport GO:0034220 365 0.017
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.017
protein maturation GO:0051604 68 0.017
male mating behavior GO:0060179 3 0.016
positive regulation of signal transduction GO:0009967 175 0.016
negative regulation of gluconeogenesis GO:0045721 1 0.016
arachidonic acid metabolic process GO:0019369 20 0.016
protein transport GO:0015031 132 0.016
negative regulation of natural killer cell mediated cytotoxicity directed against tumor cell target GO:0002859 1 0.016
cellular homeostasis GO:0019725 252 0.016
detection of chemical stimulus involved in sensory perception of bitter taste GO:0001580 4 0.016
indolalkylamine metabolic process GO:0006586 5 0.016
response to purine containing compound GO:0014074 126 0.016
organic anion transport GO:0015711 132 0.016
embryo implantation GO:0007566 15 0.016
negative regulation of molecular function GO:0044092 133 0.015
homeostatic process GO:0042592 331 0.015
positive regulation of protein modification process GO:0031401 142 0.015
axis specification GO:0009798 4 0.015
divalent metal ion transport GO:0070838 132 0.015
response to ddt GO:0046680 1 0.015
positive regulation of gene expression GO:0010628 244 0.015
regulation of protein maturation GO:1903317 50 0.015
response to molecule of fungal origin GO:0002238 3 0.015
inflammatory response GO:0006954 150 0.015
acute phase response GO:0006953 20 0.015
activation of immune response GO:0002253 26 0.015
small molecule biosynthetic process GO:0044283 124 0.015
regulation of rna biosynthetic process GO:2001141 381 0.015
hexitol biosynthetic process GO:0019406 1 0.014
positive regulation of cell proliferation GO:0008284 249 0.014
regulation of plasma lipoprotein particle levels GO:0097006 3 0.014
response to molecule of bacterial origin GO:0002237 194 0.014
response to reactive oxygen species GO:0000302 120 0.014
regulation of jak stat cascade GO:0046425 21 0.014
fatty acid beta oxidation GO:0006635 22 0.014
positive regulation of response to stimulus GO:0048584 285 0.014
regulation of extracellular matrix constituent secretion GO:0003330 2 0.014
cation transport GO:0006812 382 0.014
coenzyme metabolic process GO:0006732 86 0.014
rna metabolic process GO:0016070 406 0.014
neuron differentiation GO:0030182 368 0.014
transcription dna templated GO:0006351 377 0.014
positive regulation of cellular protein metabolic process GO:0032270 167 0.014
negative regulation of biosynthetic process GO:0009890 168 0.013
positive regulation of cell communication GO:0010647 271 0.013
monocarboxylic acid transport GO:0015718 52 0.013
monocarboxylic acid catabolic process GO:0072329 28 0.013
estrogen metabolic process GO:0008210 11 0.013
ribonucleotide metabolic process GO:0009259 231 0.013
regulation of fibrinolysis GO:0051917 2 0.013
alcohol metabolic process GO:0006066 77 0.013
metal ion transport GO:0030001 289 0.013
proteolysis GO:0006508 175 0.013
cellular response to oxidative stress GO:0034599 76 0.013
carbohydrate derivative metabolic process GO:1901135 346 0.013
organ regeneration GO:0031100 101 0.013
Rat
regulation of growth GO:0040008 105 0.013
regulation of hydrolase activity GO:0051336 143 0.013
glycerolipid metabolic process GO:0046486 67 0.013
metal ion homeostasis GO:0055065 186 0.013
phenylpropanoid catabolic process GO:0046271 3 0.013
nitrogen compound transport GO:0071705 229 0.013
peptidyl tyrosine phosphorylation GO:0018108 72 0.013
carnitine transport GO:0015879 1 0.013
protein processing GO:0016485 68 0.013
maintenance of location GO:0051235 17 0.013
regulation of transferase activity GO:0051338 123 0.013
glycosyl compound metabolic process GO:1901657 182 0.013
negative regulation of multicellular organismal process GO:0051241 203 0.013
multi multicellular organism process GO:0044706 138 0.013
regulation of lipid biosynthetic process GO:0046890 38 0.013
endocytosis GO:0006897 84 0.013
regulation of anatomical structure size GO:0090066 135 0.013
peptidyl amino acid modification GO:0018193 126 0.013
positive regulation of cell development GO:0010720 176 0.013
unsaturated fatty acid metabolic process GO:0033559 39 0.013
hormone transport GO:0009914 121 0.013
Rat
positive regulation of cell differentiation GO:0045597 217 0.012
signal release GO:0023061 145 0.012
natural killer cell mediated immune response to tumor cell GO:0002423 1 0.012
small gtpase mediated signal transduction GO:0007264 36 0.012
drug transmembrane transport GO:0006855 13 0.012
tripeptide transport GO:0042939 2 0.012
positive regulation of cellular amine metabolic process GO:0033240 3 0.012
neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 3 0.012
positive regulation of biosynthetic process GO:0009891 319 0.012
nucleic acid templated transcription GO:0097659 379 0.012
positive regulation of protein phosphorylation GO:0001934 135 0.012
aromatic compound catabolic process GO:0019439 168 0.012
neuron projection development GO:0031175 273 0.012
intracellular signal transduction GO:0035556 314 0.012
positive regulation of lipid metabolic process GO:0045834 33 0.012
cofactor metabolic process GO:0051186 95 0.012
sensory perception of bitter taste GO:0050913 4 0.012
negative regulation of innate immune response GO:0045824 4 0.012
cytoplasmic transport GO:0016482 115 0.012
single organism reproductive process GO:0044702 297 0.012
cellular cation homeostasis GO:0030003 180 0.012
cation transmembrane transport GO:0098655 263 0.012
positive regulation of jak stat cascade GO:0046427 19 0.012
positive regulation of apoptotic process GO:0043065 154 0.012
negative regulation of natural killer cell mediated cytotoxicity GO:0045953 4 0.012
cation homeostasis GO:0055080 195 0.012
purine containing compound metabolic process GO:0072521 253 0.012
negative regulation of gene expression GO:0010629 199 0.012
developmental growth GO:0048589 100 0.012
cell projection organization GO:0030030 302 0.011
negative regulation of phosphorus metabolic process GO:0010563 80 0.011
cardiovascular system development GO:0072358 134 0.011
calcium ion transport GO:0006816 131 0.011
activation of protein kinase activity GO:0032147 47 0.011
serine family amino acid metabolic process GO:0009069 12 0.011
blood circulation GO:0008015 183 0.011
cellular response to alcohol GO:0097306 87 0.011
inorganic ion transmembrane transport GO:0098660 229 0.011
regulation of calcium ion transport GO:0051924 77 0.011
isoprenoid metabolic process GO:0006720 45 0.011
positive regulation of reactive oxygen species biosynthetic process GO:1903428 2 0.011
organic hydroxy compound biosynthetic process GO:1901617 51 0.011
development of primary female sexual characteristics GO:0046545 56 0.011
cellular hormone metabolic process GO:0034754 49 0.011
positive regulation of neuron projection development GO:0010976 99 0.011
angiotensin mediated drinking behavior GO:0003051 2 0.011
toxin transport GO:1901998 3 0.011
negative regulation of cellular component organization GO:0051129 83 0.011
heart morphogenesis GO:0003007 3 0.011
response to activity GO:0014823 73 0.011
aromatic amino acid family catabolic process GO:0009074 7 0.011
multicellular organism reproduction GO:0032504 233 0.011
reproduction GO:0000003 245 0.011
sensory perception GO:0007600 101 0.011
cellular nitrogen compound catabolic process GO:0044270 163 0.011
regulation of phosphorus metabolic process GO:0051174 349 0.011
response to radiation GO:0009314 137 0.011
organophosphate catabolic process GO:0046434 148 0.011
insecticide metabolic process GO:0017143 4 0.011
response to organophosphorus GO:0046683 102 0.011
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.011
catenin import into nucleus GO:0035411 1 0.011
oligopeptide transport GO:0006857 4 0.011
monosaccharide metabolic process GO:0005996 61 0.011
ribose phosphate metabolic process GO:0019693 235 0.010
negative regulation of cellular protein metabolic process GO:0032269 106 0.010
rhythmic process GO:0048511 156 0.010
regulation of immune response to tumor cell GO:0002837 3 0.010
rna biosynthetic process GO:0032774 380 0.010
cellular response to oxygen containing compound GO:1901701 386 0.010
brain renin angiotensin system GO:0002035 3 0.010
coumarin catabolic process GO:0046226 3 0.010
oxidative demethylation GO:0070989 2 0.010
terpenoid metabolic process GO:0006721 37 0.010
regulation of vesicle mediated transport GO:0060627 81 0.010
biphenyl catabolic process GO:0070980 2 0.010
positive regulation of secretion GO:0051047 140 0.010
positive regulation of catalytic activity GO:0043085 184 0.010
regulation of natural killer cell mediated immune response to tumor cell GO:0002855 1 0.010
response to ethanol GO:0045471 162 0.010
cell migration GO:0016477 197 0.010
response to heat GO:0009408 60 0.010

Slco1b3 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.020
inherited metabolic disorder DOID:655 0 0.020
artery disease DOID:0050828 0 0.019
disease of anatomical entity DOID:7 0 0.019
vascular disease DOID:178 0 0.019
cardiovascular system disease DOID:1287 0 0.019
hypertension DOID:10763 0 0.017