Rattus norvegicus

52 known processes

Guca2b

guanylate cyclase activator 2B

Guca2b biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
lipid metabolic process GO:0006629 283 0.352
response to peptide GO:1901652 292 0.221
response to nutrient levels GO:0031667 370 0.208
response to other organism GO:0051707 220 0.174
regulation of locomotion GO:0040012 148 0.162
protein complex subunit organization GO:0071822 302 0.158
neuron differentiation GO:0030182 368 0.138
response to insulin GO:0032868 133 0.136
response to external biotic stimulus GO:0043207 221 0.133
positive regulation of cellular biosynthetic process GO:0031328 295 0.121
carboxylic acid metabolic process GO:0019752 289 0.112
regulation of cell development GO:0060284 263 0.110
regulation of cellular localization GO:0060341 263 0.109
regulation of nervous system development GO:0051960 264 0.099
positive regulation of multicellular organismal process GO:0051240 387 0.098
protein localization GO:0008104 191 0.095
cell cell signaling GO:0007267 335 0.094
positive regulation of transport GO:0051050 245 0.090
response to lipopolysaccharide GO:0032496 191 0.085
response to bacterium GO:0009617 200 0.081
anatomical structure morphogenesis GO:0009653 298 0.081
cellular response to endogenous stimulus GO:0071495 377 0.081
growth GO:0040007 165 0.081
response to extracellular stimulus GO:0009991 380 0.080
positive regulation of nervous system development GO:0051962 178 0.077
neuron projection development GO:0031175 273 0.076
response to carbohydrate GO:0009743 183 0.076
cellular component assembly GO:0022607 360 0.073
positive regulation of catalytic activity GO:0043085 184 0.072
head development GO:0060322 247 0.071
regulation of protein modification process GO:0031399 194 0.071
regulation of protein metabolic process GO:0051246 289 0.070
gland development GO:0048732 155 0.068
cellular lipid metabolic process GO:0044255 208 0.067
cellular ketone metabolic process GO:0042180 51 0.066
cellular response to oxygen containing compound GO:1901701 386 0.066
response to corticosteroid GO:0031960 235 0.065
response to peptide hormone GO:0043434 278 0.065
regulation of phosphorus metabolic process GO:0051174 349 0.065
macromolecular complex subunit organization GO:0043933 339 0.064
regulation of molecular function GO:0065009 398 0.062
regulation of lipid metabolic process GO:0019216 68 0.062
regulation of multicellular organismal development GO:2000026 376 0.062
cellular response to stress GO:0033554 269 0.061
cellular response to lipid GO:0071396 201 0.061
oxoacid metabolic process GO:0043436 290 0.060
cellular response to extracellular stimulus GO:0031668 73 0.060
central nervous system development GO:0007417 311 0.058
cellular response to hormone stimulus GO:0032870 247 0.058
response to oxidative stress GO:0006979 186 0.057
cytoskeleton organization GO:0007010 111 0.057
regulation of catalytic activity GO:0050790 304 0.056
regulation of cell migration GO:0030334 128 0.056
regulation of neuron death GO:1901214 115 0.055
positive regulation of developmental process GO:0051094 283 0.055
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.055
organic substance catabolic process GO:1901575 316 0.055
positive regulation of molecular function GO:0044093 230 0.054
transcription from rna polymerase ii promoter GO:0006366 252 0.053
positive regulation of cell communication GO:0010647 271 0.053
regulation of cell differentiation GO:0045595 320 0.052
neuron development GO:0048666 286 0.052
neuron death GO:0070997 127 0.051
organophosphate metabolic process GO:0019637 370 0.050
positive regulation of intracellular signal transduction GO:1902533 138 0.050
cellular component movement GO:0006928 248 0.049
regulation of cell motility GO:2000145 131 0.048
response to nutrient GO:0007584 248 0.048
regulation of neurogenesis GO:0050767 247 0.047
cellular response to nitrogen compound GO:1901699 210 0.047
regulation of secretion GO:0051046 224 0.046
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.045
hormone biosynthetic process GO:0042446 25 0.045
heterocycle catabolic process GO:0046700 167 0.044
response to glucocorticoid GO:0051384 223 0.044
regulation of neuron differentiation GO:0045664 208 0.043
regulation of cellular amino acid metabolic process GO:0006521 2 0.042
cellular response to organic cyclic compound GO:0071407 202 0.042
regulation of cellular component organization GO:0051128 368 0.040
response to ethanol GO:0045471 162 0.040
regulation of intracellular signal transduction GO:1902531 218 0.040
positive regulation of biosynthetic process GO:0009891 319 0.039
regulation of cellular ketone metabolic process GO:0010565 27 0.039
positive regulation of protein metabolic process GO:0051247 178 0.039
positive regulation of synaptic transmission GO:0050806 62 0.038
response to organophosphorus GO:0046683 102 0.038
response to hexose GO:0009746 144 0.037
cellular response to peptide GO:1901653 133 0.037
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.037
cellular component biogenesis GO:0044085 368 0.036
sodium ion transport GO:0006814 82 0.036
cellular response to organonitrogen compound GO:0071417 197 0.035
positive regulation of nucleic acid templated transcription GO:1903508 197 0.035
response to molecule of bacterial origin GO:0002237 194 0.035
single organism carbohydrate metabolic process GO:0044723 118 0.035
intracellular signal transduction GO:0035556 314 0.035
carboxylic acid transport GO:0046942 115 0.035
synaptic growth at neuromuscular junction GO:0051124 1 0.035
regulation of system process GO:0044057 208 0.035
cell projection organization GO:0030030 302 0.034
response to estradiol GO:0032355 164 0.033
organic acid metabolic process GO:0006082 292 0.033
regulation of transcription dna templated GO:0006355 374 0.033
positive regulation of cellular protein metabolic process GO:0032270 167 0.033
positive regulation of cell proliferation GO:0008284 249 0.033
carbohydrate derivative metabolic process GO:1901135 346 0.033
Mouse
regulation of ion transport GO:0043269 245 0.033
positive regulation of cell differentiation GO:0045597 217 0.033
actin filament based process GO:0030029 86 0.032
cation transmembrane transport GO:0098655 263 0.032
tissue development GO:0009888 252 0.032
organonitrogen compound catabolic process GO:1901565 179 0.031
macromolecule localization GO:0033036 252 0.031
regulation of rna biosynthetic process GO:2001141 381 0.031
positive regulation of rna metabolic process GO:0051254 203 0.031
positive regulation of phosphate metabolic process GO:0045937 262 0.030
single organism behavior GO:0044708 130 0.030
secretion GO:0046903 307 0.030
Mouse
organophosphate catabolic process GO:0046434 148 0.030
actin cytoskeleton organization GO:0030036 73 0.030
positive regulation of neurogenesis GO:0050769 165 0.030
organelle organization GO:0006996 266 0.030
response to growth factor GO:0070848 189 0.030
single organism biosynthetic process GO:0044711 342 0.029
cellular response to oxidative stress GO:0034599 76 0.029
regulation of kinase activity GO:0043549 117 0.029
cation transport GO:0006812 382 0.029
macromolecular complex assembly GO:0065003 273 0.029
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.029
regulation of phosphate metabolic process GO:0019220 349 0.028
peptidyl amino acid modification GO:0018193 126 0.028
nitrogen compound transport GO:0071705 229 0.028
lipid biosynthetic process GO:0008610 128 0.027
response to purine containing compound GO:0014074 126 0.027
cellular homeostasis GO:0019725 252 0.027
positive regulation of phosphorus metabolic process GO:0010562 262 0.027
nucleoside metabolic process GO:0009116 179 0.027
response to acid chemical GO:0001101 222 0.027
brain development GO:0007420 247 0.027
positive regulation of cellular amine metabolic process GO:0033240 3 0.027
regulation of neuron projection development GO:0010975 161 0.027
ion homeostasis GO:0050801 212 0.026
protein oligomerization GO:0051259 191 0.026
single organism catabolic process GO:0044712 283 0.026
response to camp GO:0051591 91 0.026
response to biotic stimulus GO:0009607 226 0.026
cellular response to alcohol GO:0097306 87 0.026
response to hypoxia GO:0001666 231 0.025
gliogenesis GO:0042063 93 0.025
catabolic process GO:0009056 351 0.025
inflammatory response GO:0006954 150 0.025
secretion by cell GO:0032940 248 0.025
regulation of secretion by cell GO:1903530 208 0.025
actin filament organization GO:0007015 42 0.025
ras protein signal transduction GO:0007265 29 0.025
regeneration GO:0031099 163 0.025
positive regulation of cellular component organization GO:0051130 200 0.025
rna biosynthetic process GO:0032774 380 0.025
cellular catabolic process GO:0044248 295 0.024
response to reactive oxygen species GO:0000302 120 0.024
transmembrane transport GO:0055085 412 0.024
rna metabolic process GO:0016070 406 0.024
reproductive process GO:0022414 372 0.024
cell activation GO:0001775 97 0.024
regulation of rna metabolic process GO:0051252 391 0.024
vesicle mediated transport GO:0016192 181 0.024
response to inorganic substance GO:0010035 377 0.024
response to monosaccharide GO:0034284 159 0.023
cellular carbohydrate metabolic process GO:0044262 72 0.023
lipid modification GO:0030258 52 0.023
blood circulation GO:0008015 183 0.023
Mouse
motor neuron axon guidance GO:0008045 1 0.023
actin filament bundle organization GO:0061572 19 0.023
metal ion transport GO:0030001 289 0.022
nucleic acid templated transcription GO:0097659 379 0.022
carboxylic acid biosynthetic process GO:0046394 83 0.022
regulation of cytoskeleton organization GO:0051493 49 0.022
epithelial cell proliferation GO:0050673 54 0.022
cellular response to lipopolysaccharide GO:0071222 55 0.022
neurological system process GO:0050877 219 0.022
response to alkaloid GO:0043279 132 0.022
protein phosphorylation GO:0006468 345 0.022
negative regulation of cell death GO:0060548 229 0.022
response to metal ion GO:0010038 253 0.021
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.021
multicellular organism reproduction GO:0032504 233 0.021
amine metabolic process GO:0009308 38 0.021
positive regulation of cell motility GO:2000147 97 0.021
localization of cell GO:0051674 202 0.021
regulation of lipid biosynthetic process GO:0046890 38 0.021
response to interleukin 1 GO:0070555 55 0.021
regulation of hormone levels GO:0010817 187 0.021
aging GO:0007568 241 0.021
cell growth GO:0016049 104 0.021
heart morphogenesis GO:0003007 3 0.021
cellular amine metabolic process GO:0044106 38 0.020
response to radiation GO:0009314 137 0.020
protein complex assembly GO:0006461 263 0.020
regulation of cellular component biogenesis GO:0044087 86 0.020
vasoconstriction GO:0042310 54 0.020
glial cell differentiation GO:0010001 65 0.020
positive regulation of transferase activity GO:0051347 81 0.020
positive regulation of response to stimulus GO:0048584 285 0.020
positive regulation of transcription dna templated GO:0045893 197 0.020
cellular response to vitamin e GO:0071306 3 0.020
positive regulation of protein modification process GO:0031401 142 0.020
positive regulation of cell migration GO:0030335 96 0.019
positive regulation of gene expression GO:0010628 244 0.019
axis specification GO:0009798 4 0.019
small gtpase mediated signal transduction GO:0007264 36 0.019
inorganic cation transmembrane transport GO:0098662 202 0.019
carbohydrate biosynthetic process GO:0016051 42 0.019
positive regulation of rna biosynthetic process GO:1902680 197 0.019
hormone metabolic process GO:0042445 69 0.019
cellular chemical homeostasis GO:0055082 247 0.019
organic acid transport GO:0015849 116 0.019
cytosolic calcium ion homeostasis GO:0051480 140 0.019
telencephalon development GO:0021537 62 0.019
positive regulation of signaling GO:0023056 270 0.019
cytokine biosynthetic process GO:0042089 3 0.018
synaptic transmission GO:0007268 235 0.018
regulation of signal transduction GO:0009966 318 0.018
regulation of actin filament based process GO:0032970 42 0.018
aromatic compound catabolic process GO:0019439 168 0.018
positive regulation of catabolic process GO:0009896 78 0.018
protein heterooligomerization GO:0051291 89 0.018
chemical homeostasis GO:0048878 292 0.018
organic anion transport GO:0015711 132 0.018
positive regulation of phosphorylation GO:0042327 177 0.018
embryo development GO:0009790 49 0.017
cellular ion homeostasis GO:0006873 184 0.017
peptide biosynthetic process GO:0043043 3 0.017
response to starvation GO:0042594 59 0.017
cellular divalent inorganic cation homeostasis GO:0072503 162 0.017
regulation of cellular protein metabolic process GO:0032268 267 0.017
nucleoside triphosphate metabolic process GO:0009141 144 0.017
muscle structure development GO:0061061 87 0.017
cellular response to biotic stimulus GO:0071216 59 0.017
nucleoside triphosphate catabolic process GO:0009143 123 0.017
regulation of phosphorylation GO:0042325 248 0.017
negative regulation of neuron death GO:1901215 69 0.017
response to retinoic acid GO:0032526 63 0.017
response to hydrogen peroxide GO:0042542 89 0.017
phospholipid metabolic process GO:0006644 61 0.017
cellular response to growth factor stimulus GO:0071363 162 0.016
steroid metabolic process GO:0008202 73 0.016
regulation of transferase activity GO:0051338 123 0.016
cellular amino acid metabolic process GO:0006520 107 0.016
response to estrogen GO:0043627 232 0.016
cell motility GO:0048870 202 0.016
sensory organ development GO:0007423 74 0.016
regulation of cellular component movement GO:0051270 150 0.016
purine nucleoside triphosphate metabolic process GO:0009144 141 0.016
cell migration GO:0016477 197 0.015
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.015
defense response GO:0006952 194 0.015
regulation of hormone secretion GO:0046883 106 0.015
cellular nitrogen compound catabolic process GO:0044270 163 0.015
carbohydrate homeostasis GO:0033500 75 0.015
cellular response to interleukin 1 GO:0071347 37 0.015
behavior GO:0007610 205 0.015
developmental growth GO:0048589 100 0.015
g protein coupled receptor signaling pathway GO:0007186 242 0.015
organic hydroxy compound transport GO:0015850 77 0.015
homeostatic process GO:0042592 331 0.015
regulation of protein phosphorylation GO:0001932 183 0.015
regulation of establishment of protein localization GO:0070201 69 0.015
rhythmic process GO:0048511 156 0.015
macromolecule catabolic process GO:0009057 58 0.014
negative regulation of metabolic process GO:0009892 331 0.014
positive regulation of apoptotic process GO:0043065 154 0.014
nucleobase containing compound catabolic process GO:0034655 152 0.014
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.014
positive regulation of neuron differentiation GO:0045666 126 0.014
circulatory system process GO:0003013 183 0.014
Mouse
regulation of protein transport GO:0051223 68 0.014
regulation of catabolic process GO:0009894 113 0.014
proteolysis GO:0006508 175 0.014
striated muscle tissue development GO:0014706 58 0.014
carbohydrate metabolic process GO:0005975 130 0.014
cell adhesion GO:0007155 110 0.014
regulation of cell proliferation GO:0042127 359 0.014
multicellular organismal reproductive process GO:0048609 233 0.014
monosaccharide metabolic process GO:0005996 61 0.014
positive regulation of locomotion GO:0040017 102 0.014
response to decreased oxygen levels GO:0036293 237 0.013
response to transition metal nanoparticle GO:1990267 122 0.013
regulation of cellular catabolic process GO:0031329 101 0.013
intracellular protein transport GO:0006886 79 0.013
positive regulation of cellular component movement GO:0051272 102 0.013
anion transport GO:0006820 178 0.013
protein complex biogenesis GO:0070271 263 0.013
regulation of organelle organization GO:0033043 80 0.013
regulation of cellular amine metabolic process GO:0033238 8 0.013
circadian regulation of gene expression GO:0032922 3 0.013
glucan metabolic process GO:0044042 23 0.013
sodium ion transmembrane transport GO:0035725 67 0.013
transcription dna templated GO:0006351 377 0.013
positive regulation of kinase activity GO:0033674 77 0.013
ribonucleoside triphosphate metabolic process GO:0009199 141 0.013
spermatogenesis GO:0007283 99 0.013
digestive system development GO:0055123 41 0.013
glucose homeostasis GO:0042593 75 0.013
positive regulation of insulin secretion GO:0032024 36 0.013
rho protein signal transduction GO:0007266 11 0.013
response to vitamin e GO:0033197 24 0.013
positive regulation of secretion by cell GO:1903532 128 0.012
purine nucleotide catabolic process GO:0006195 136 0.012
circadian rhythm GO:0007623 88 0.012
cardiovascular system development GO:0072358 134 0.012
monocarboxylic acid metabolic process GO:0032787 152 0.012
positive regulation of neuron projection development GO:0010976 99 0.012
positive regulation of cellular catabolic process GO:0031331 71 0.012
response to nicotine GO:0035094 51 0.012
purine ribonucleoside catabolic process GO:0046130 124 0.012
organ morphogenesis GO:0009887 75 0.012
cellular protein localization GO:0034613 122 0.012
dendrite development GO:0016358 72 0.012
response to fibroblast growth factor GO:0071774 29 0.012
ion transmembrane transport GO:0034220 365 0.012
purine nucleoside catabolic process GO:0006152 124 0.012
locomotion GO:0040011 237 0.012
cholesterol homeostasis GO:0042632 3 0.012
cell morphogenesis involved in neuron differentiation GO:0048667 106 0.012
chemotaxis GO:0006935 66 0.012
positive regulation of cell development GO:0010720 176 0.012
dna metabolic process GO:0006259 96 0.012
purine nucleoside metabolic process GO:0042278 169 0.012
nucleoside monophosphate catabolic process GO:0009125 56 0.011
regulation of pancreatic stellate cell proliferation GO:2000229 2 0.011
generation of precursor metabolites and energy GO:0006091 62 0.011
regulation of nucleic acid templated transcription GO:1903506 380 0.011
regulation of protein localization GO:0032880 81 0.011
negative regulation of cellular protein metabolic process GO:0032269 106 0.011
neural crest cell migration GO:0001755 1 0.011
wound healing GO:0042060 122 0.011
response to fungicide GO:0060992 20 0.011
positive regulation of secretion GO:0051047 140 0.011
multi organism reproductive process GO:0044703 262 0.011
regulation of dendrite development GO:0050773 59 0.011
regulation of cytokine biosynthetic process GO:0042035 3 0.011
neural crest cell development GO:0014032 2 0.011
biological adhesion GO:0022610 110 0.011
liver development GO:0001889 90 0.011
regulation of protein kinase activity GO:0045859 105 0.011
regulation of fat cell differentiation GO:0045598 3 0.011
response to electrical stimulus GO:0051602 56 0.011
vitamin d receptor signaling pathway GO:0070561 1 0.011
nucleobase containing small molecule metabolic process GO:0055086 316 0.011
regulation of cell projection organization GO:0031344 175 0.011
response to glucose GO:0009749 136 0.011
peptidyl tyrosine phosphorylation GO:0018108 72 0.011
intracellular transport GO:0046907 185 0.011
nucleoside phosphate catabolic process GO:1901292 140 0.011
response to cocaine GO:0042220 39 0.011
calcium ion transmembrane transport GO:0070588 70 0.011
axon development GO:0061564 96 0.011
programmed cell death GO:0012501 392 0.011
peptidyl tyrosine modification GO:0018212 72 0.010
positive regulation of protein kinase activity GO:0045860 73 0.010
purine nucleoside triphosphate catabolic process GO:0009146 122 0.010
negative regulation of macromolecule metabolic process GO:0010605 260 0.010
cellular response to molecule of bacterial origin GO:0071219 56 0.010
vascular process in circulatory system GO:0003018 96 0.010
positive regulation of cellular component biogenesis GO:0044089 55 0.010
negative regulation of signaling GO:0023057 157 0.010
nucleotide catabolic process GO:0009166 139 0.010
regulation of peptide secretion GO:0002791 82 0.010
cell morphogenesis involved in differentiation GO:0000904 119 0.010
neuropeptide signaling pathway GO:0007218 29 0.010

Guca2b disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.020
disease of anatomical entity DOID:7 0 0.016
musculoskeletal system disease DOID:17 0 0.016
connective tissue disease DOID:65 0 0.016
bone disease DOID:0080001 0 0.013
nervous system disease DOID:863 0 0.010