Rattus norvegicus

0 known processes

P4ha2

prolyl 4-hydroxylase, alpha polypeptide II

P4ha2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
macromolecular complex subunit organization GO:0043933 339 0.077
rna biosynthetic process GO:0032774 380 0.075
response to hypoxia GO:0001666 231 0.061
reproductive process GO:0022414 372 0.060
regulation of rna biosynthetic process GO:2001141 381 0.060
regulation of transcription dna templated GO:0006355 374 0.059
regulation of rna metabolic process GO:0051252 391 0.058
nucleic acid templated transcription GO:0097659 379 0.056
regulation of apoptotic process GO:0042981 335 0.055
response to oxygen levels GO:0070482 265 0.054
negative regulation of macromolecule metabolic process GO:0010605 260 0.053
regulation of cell proliferation GO:0042127 359 0.053
cellular response to oxygen containing compound GO:1901701 386 0.052
regulation of nucleic acid templated transcription GO:1903506 380 0.052
cellular component assembly GO:0022607 360 0.052
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.051
negative regulation of gene expression GO:0010629 199 0.050
organelle organization GO:0006996 266 0.050
response to estrogen GO:0043627 232 0.049
response to estradiol GO:0032355 164 0.048
nucleoside phosphate metabolic process GO:0006753 283 0.048
ribonucleotide metabolic process GO:0009259 231 0.048
nucleotide metabolic process GO:0009117 279 0.048
carbohydrate derivative metabolic process GO:1901135 346 0.047
negative regulation of cellular metabolic process GO:0031324 281 0.047
cellular response to organonitrogen compound GO:0071417 197 0.046
transcription dna templated GO:0006351 377 0.046
central nervous system development GO:0007417 311 0.046
rna metabolic process GO:0016070 406 0.046
negative regulation of metabolic process GO:0009892 331 0.046
protein complex subunit organization GO:0071822 302 0.045
cellular component biogenesis GO:0044085 368 0.045
response to decreased oxygen levels GO:0036293 237 0.045
regulation of cellular component organization GO:0051128 368 0.044
organophosphate metabolic process GO:0019637 370 0.043
negative regulation of cellular biosynthetic process GO:0031327 161 0.043
response to other organism GO:0051707 220 0.043
positive regulation of cell differentiation GO:0045597 217 0.042
apoptotic process GO:0006915 381 0.042
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.042
transcription from rna polymerase ii promoter GO:0006366 252 0.041
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.041
response to peptide GO:1901652 292 0.040
homeostatic process GO:0042592 331 0.039
regulation of cell differentiation GO:0045595 320 0.038
purine nucleotide metabolic process GO:0006163 229 0.038
nucleobase containing small molecule metabolic process GO:0055086 316 0.036
positive regulation of cell development GO:0010720 176 0.036
regulation of multicellular organismal development GO:2000026 376 0.036
regulation of cell development GO:0060284 263 0.035
cellular response to endogenous stimulus GO:0071495 377 0.035
organic acid metabolic process GO:0006082 292 0.035
Mouse
ribose phosphate metabolic process GO:0019693 235 0.035
purine ribonucleotide metabolic process GO:0009150 227 0.035
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.035
regulation of cellular localization GO:0060341 263 0.034
nitrogen compound transport GO:0071705 229 0.034
multicellular organism reproduction GO:0032504 233 0.034
purine containing compound metabolic process GO:0072521 253 0.034
cellular response to stress GO:0033554 269 0.033
response to inorganic substance GO:0010035 377 0.033
negative regulation of rna metabolic process GO:0051253 123 0.032
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.032
regulation of phosphorus metabolic process GO:0051174 349 0.032
regulation of programmed cell death GO:0043067 341 0.032
multi organism reproductive process GO:0044703 262 0.032
neuron differentiation GO:0030182 368 0.032
negative regulation of rna biosynthetic process GO:1902679 118 0.031
cellular catabolic process GO:0044248 295 0.031
programmed cell death GO:0012501 392 0.031
regulation of catalytic activity GO:0050790 304 0.031
cellular ketone metabolic process GO:0042180 51 0.031
cardiovascular system development GO:0072358 134 0.030
blood circulation GO:0008015 183 0.030
positive regulation of gene expression GO:0010628 244 0.030
organophosphate catabolic process GO:0046434 148 0.030
response to glucocorticoid GO:0051384 223 0.030
intracellular signal transduction GO:0035556 314 0.030
single organism reproductive process GO:0044702 297 0.029
positive regulation of developmental process GO:0051094 283 0.029
single organism catabolic process GO:0044712 283 0.029
regulation of molecular function GO:0065009 398 0.029
positive regulation of response to stimulus GO:0048584 285 0.028
secretion GO:0046903 307 0.028
protein complex assembly GO:0006461 263 0.028
organic substance catabolic process GO:1901575 316 0.027
positive regulation of biosynthetic process GO:0009891 319 0.027
amine metabolic process GO:0009308 38 0.027
negative regulation of cell communication GO:0010648 158 0.026
regulation of neuron differentiation GO:0045664 208 0.026
neuron projection development GO:0031175 273 0.025
response to extracellular stimulus GO:0009991 380 0.025
macromolecular complex assembly GO:0065003 273 0.025
g protein coupled receptor signaling pathway GO:0007186 242 0.025
positive regulation of cellular component organization GO:0051130 200 0.025
cellular amine metabolic process GO:0044106 38 0.024
regulation of phosphate metabolic process GO:0019220 349 0.024
cellular response to hormone stimulus GO:0032870 247 0.024
regulation of nervous system development GO:0051960 264 0.024
response to bacterium GO:0009617 200 0.024
regulation of cellular amino acid metabolic process GO:0006521 2 0.024
single organism biosynthetic process GO:0044711 342 0.024
response to carbohydrate GO:0009743 183 0.024
positive regulation of signaling GO:0023056 270 0.024
regulation of neurogenesis GO:0050767 247 0.024
positive regulation of cellular biosynthetic process GO:0031328 295 0.023
response to biotic stimulus GO:0009607 226 0.023
positive regulation of neurogenesis GO:0050769 165 0.023
protein oligomerization GO:0051259 191 0.023
positive regulation of cellular amine metabolic process GO:0033240 3 0.023
purine nucleoside metabolic process GO:0042278 169 0.023
cellular cation homeostasis GO:0030003 180 0.023
response to ketone GO:1901654 182 0.023
heterocycle catabolic process GO:0046700 167 0.023
enzyme linked receptor protein signaling pathway GO:0007167 116 0.023
response to nutrient levels GO:0031667 370 0.023
regulation of signal transduction GO:0009966 318 0.023
glycosyl compound metabolic process GO:1901657 182 0.022
response to oxidative stress GO:0006979 186 0.022
cellular response to nitrogen compound GO:1901699 210 0.022
negative regulation of apoptotic process GO:0043066 181 0.022
protein complex biogenesis GO:0070271 263 0.022
response to peptide hormone GO:0043434 278 0.022
regulation of intracellular signal transduction GO:1902531 218 0.022
positive regulation of cell communication GO:0010647 271 0.022
negative regulation of signaling GO:0023057 157 0.022
response to metal ion GO:0010038 253 0.021
regulation of nucleotide metabolic process GO:0006140 117 0.021
positive regulation of molecular function GO:0044093 230 0.021
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.021
secretion by cell GO:0032940 248 0.021
ion transmembrane transport GO:0034220 365 0.021
vesicle mediated transport GO:0016192 181 0.021
oxidation reduction process GO:0055114 304 0.021
Mouse Rat Worm
cell projection organization GO:0030030 302 0.021
nucleoside catabolic process GO:0009164 126 0.021
purine nucleoside catabolic process GO:0006152 124 0.021
negative regulation of transcription dna templated GO:0045892 116 0.020
regulation of cellular ketone metabolic process GO:0010565 27 0.020
response to external biotic stimulus GO:0043207 221 0.020
regulation of hormone levels GO:0010817 187 0.020
response to reactive oxygen species GO:0000302 120 0.020
renal system development GO:0072001 67 0.020
head development GO:0060322 247 0.020
purine ribonucleoside metabolic process GO:0046128 168 0.020
negative regulation of biosynthetic process GO:0009890 168 0.020
organonitrogen compound biosynthetic process GO:1901566 167 0.020
negative regulation of programmed cell death GO:0043069 183 0.020
chemical homeostasis GO:0048878 292 0.020
circulatory system process GO:0003013 183 0.020
response to corticosteroid GO:0031960 235 0.020
anatomical structure morphogenesis GO:0009653 298 0.019
oxoacid metabolic process GO:0043436 290 0.019
Mouse
protein homooligomerization GO:0051260 91 0.019
response to growth factor GO:0070848 189 0.019
regulation of cellular amine metabolic process GO:0033238 8 0.019
positive regulation of programmed cell death GO:0043068 157 0.019
carboxylic acid metabolic process GO:0019752 289 0.019
Mouse
cellular nitrogen compound catabolic process GO:0044270 163 0.019
regulation of purine nucleotide metabolic process GO:1900542 115 0.019
response to wounding GO:0009611 254 0.019
cellular response to growth factor stimulus GO:0071363 162 0.019
positive regulation of multicellular organismal process GO:0051240 387 0.019
negative regulation of nucleic acid templated transcription GO:1903507 117 0.019
positive regulation of cell proliferation GO:0008284 249 0.019
hormone secretion GO:0046879 115 0.019
purine containing compound catabolic process GO:0072523 138 0.019
hormone transport GO:0009914 121 0.019
response to hexose GO:0009746 144 0.018
protein localization GO:0008104 191 0.018
cellular response to organic cyclic compound GO:0071407 202 0.018
macromolecule localization GO:0033036 252 0.018
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.018
negative regulation of cell death GO:0060548 229 0.018
organic cyclic compound catabolic process GO:1901361 175 0.018
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.018
cellular homeostasis GO:0019725 252 0.018
cellular chemical homeostasis GO:0055082 247 0.018
reproduction GO:0000003 245 0.018
regulation of neuron projection development GO:0010975 161 0.018
positive regulation of nervous system development GO:0051962 178 0.018
neuron development GO:0048666 286 0.018
positive regulation of transcription dna templated GO:0045893 197 0.018
cellular amino acid metabolic process GO:0006520 107 0.017
Mouse
catabolic process GO:0009056 351 0.017
single organism intracellular transport GO:1902582 166 0.017
aging GO:0007568 241 0.017
brain development GO:0007420 247 0.017
bmp signaling pathway GO:0030509 4 0.017
nucleoside triphosphate metabolic process GO:0009141 144 0.017
regulation of response to external stimulus GO:0032101 106 0.017
ribonucleoside triphosphate metabolic process GO:0009199 141 0.017
regulation of canonical wnt signaling pathway GO:0060828 4 0.017
cellular macromolecule localization GO:0070727 122 0.017
regulation of blood pressure GO:0008217 83 0.017
heart morphogenesis GO:0003007 3 0.017
developmental process involved in reproduction GO:0003006 159 0.017
purine ribonucleoside triphosphate metabolic process GO:0009205 140 0.017
response to alkaloid GO:0043279 132 0.017
nucleoside phosphate biosynthetic process GO:1901293 102 0.017
vascular process in circulatory system GO:0003018 96 0.016
response to glucose GO:0009749 136 0.016
circulatory system development GO:0072359 134 0.016
ion homeostasis GO:0050801 212 0.016
regulation of smooth muscle cell proliferation GO:0048660 75 0.016
cation transport GO:0006812 382 0.016
transmembrane transport GO:0055085 412 0.016
lipid metabolic process GO:0006629 283 0.016
carbohydrate derivative catabolic process GO:1901136 147 0.016
cellular ion homeostasis GO:0006873 184 0.016
purine nucleoside triphosphate metabolic process GO:0009144 141 0.016
intracellular transport GO:0046907 185 0.016
urogenital system development GO:0001655 78 0.016
carbohydrate metabolic process GO:0005975 130 0.016
anion transport GO:0006820 178 0.015
reproductive structure development GO:0048608 128 0.015
positive regulation of apoptotic process GO:0043065 154 0.015
negative regulation of signal transduction GO:0009968 83 0.015
response to monosaccharide GO:0034284 159 0.015
positive regulation of transport GO:0051050 245 0.015
behavior GO:0007610 205 0.015
metal ion homeostasis GO:0055065 186 0.015
purine nucleoside triphosphate catabolic process GO:0009146 122 0.015
protein phosphorylation GO:0006468 345 0.015
carbohydrate derivative biosynthetic process GO:1901137 124 0.015
nucleoside triphosphate catabolic process GO:0009143 123 0.015
synaptic transmission GO:0007268 235 0.015
regulation of system process GO:0044057 208 0.015
regulation of hydrolase activity GO:0051336 143 0.015
positive regulation of nucleic acid templated transcription GO:1903508 197 0.015
cellular response to peptide GO:1901653 133 0.015
single organism organelle organization GO:1902589 180 0.015
muscle cell proliferation GO:0033002 84 0.015
muscle contraction GO:0006936 88 0.015
sexual reproduction GO:0019953 148 0.015
organonitrogen compound catabolic process GO:1901565 179 0.015
female pregnancy GO:0007565 122 0.015
negative regulation of cellular protein metabolic process GO:0032269 106 0.015
regulation of anatomical structure size GO:0090066 135 0.015
positive regulation of phosphate metabolic process GO:0045937 262 0.015
organ regeneration GO:0031100 101 0.014
signal release GO:0023061 145 0.014
gastrulation GO:0007369 2 0.014
development of primary sexual characteristics GO:0045137 107 0.014
positive regulation of cytosolic calcium ion concentration GO:0007204 122 0.014
divalent inorganic cation transport GO:0072511 134 0.014
positive regulation of catalytic activity GO:0043085 184 0.014
negative regulation of protein metabolic process GO:0051248 114 0.014
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.014
reproductive system development GO:0061458 128 0.014
gamete generation GO:0007276 124 0.014
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 85 0.014
positive regulation of rna biosynthetic process GO:1902680 197 0.014
cellular lipid metabolic process GO:0044255 208 0.014
positive regulation of phosphorylation GO:0042327 177 0.014
response to mineralocorticoid GO:0051385 49 0.014
nucleoside phosphate catabolic process GO:1901292 140 0.014
negative regulation of molecular function GO:0044092 133 0.014
positive regulation of neuron differentiation GO:0045666 126 0.014
synaptic growth at neuromuscular junction GO:0051124 1 0.014
purine nucleotide catabolic process GO:0006195 136 0.014
response to vitamin GO:0033273 131 0.014
positive regulation of signal transduction GO:0009967 175 0.014
smooth muscle cell proliferation GO:0048659 77 0.014
cellular protein localization GO:0034613 122 0.014
sex differentiation GO:0007548 113 0.014
actin cytoskeleton organization GO:0030036 73 0.014
regulation of catabolic process GO:0009894 113 0.013
regulation of phosphorylation GO:0042325 248 0.013
nucleotide catabolic process GO:0009166 139 0.013
aromatic compound catabolic process GO:0019439 168 0.013
positive regulation of neuron projection development GO:0010976 99 0.013
divalent inorganic cation homeostasis GO:0072507 165 0.013
positive regulation of smooth muscle cell proliferation GO:0048661 51 0.013
small gtpase mediated signal transduction GO:0007264 36 0.013
ribonucleoside metabolic process GO:0009119 174 0.013
regulation of secretion by cell GO:1903530 208 0.013
cellular metal ion homeostasis GO:0006875 172 0.013
response to acid chemical GO:0001101 222 0.013
cellular carbohydrate metabolic process GO:0044262 72 0.013
purine ribonucleotide catabolic process GO:0009154 136 0.013
regulation of cellular protein metabolic process GO:0032268 267 0.013
metal ion transport GO:0030001 289 0.013
cell type specific apoptotic process GO:0097285 134 0.013
single organism cellular localization GO:1902580 102 0.013
regulation of fat cell differentiation GO:0045598 3 0.013
carbohydrate homeostasis GO:0033500 75 0.013
nucleobase containing compound catabolic process GO:0034655 152 0.013
positive regulation of rna metabolic process GO:0051254 203 0.013
cellular response to lipid GO:0071396 201 0.013
glycosyl compound catabolic process GO:1901658 126 0.013
taxis GO:0042330 67 0.013
nucleoside metabolic process GO:0009116 179 0.013
purine ribonucleoside catabolic process GO:0046130 124 0.013
regulation of secretion GO:0051046 224 0.013
reactive oxygen species metabolic process GO:0072593 37 0.013
cytosolic calcium ion homeostasis GO:0051480 140 0.013
hormone metabolic process GO:0042445 69 0.012
negative regulation of developmental process GO:0051093 125 0.012
response to nutrient GO:0007584 248 0.012
regeneration GO:0031099 163 0.012
regulation of cell projection organization GO:0031344 175 0.012
glucose homeostasis GO:0042593 75 0.012
axis specification GO:0009798 4 0.012
cytoplasmic transport GO:0016482 115 0.012
negative regulation of secretion GO:0051048 82 0.012
nucleotide biosynthetic process GO:0009165 98 0.012
positive regulation of phosphorus metabolic process GO:0010562 262 0.012
stress activated protein kinase signaling cascade GO:0031098 37 0.012
negative regulation of response to stimulus GO:0048585 155 0.012
cellular response to oxidative stress GO:0034599 76 0.012
lipid storage GO:0019915 1 0.012
multi multicellular organism process GO:0044706 138 0.012
positive regulation of endothelial cell migration GO:0010595 4 0.012
kidney development GO:0001822 67 0.012
cellular component movement GO:0006928 248 0.012
organophosphate biosynthetic process GO:0090407 143 0.012
purine ribonucleoside triphosphate catabolic process GO:0009207 122 0.012
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090101 2 0.012
calcium ion homeostasis GO:0055074 162 0.012
organic anion transport GO:0015711 132 0.012
negative regulation of multicellular organismal process GO:0051241 203 0.012
peptide hormone secretion GO:0030072 84 0.012
cation homeostasis GO:0055080 195 0.011
amide transport GO:0042886 105 0.011
response to transition metal nanoparticle GO:1990267 122 0.011
male gamete generation GO:0048232 99 0.011
multicellular organism growth GO:0035264 1 0.011
regulation of response to stress GO:0080134 126 0.011
ribonucleoside triphosphate catabolic process GO:0009203 122 0.011
response to ammonium ion GO:0060359 71 0.011
ras protein signal transduction GO:0007265 29 0.011
inflammatory response GO:0006954 150 0.011
response to starvation GO:0042594 59 0.011
calcium ion transport GO:0006816 131 0.011
cytokine biosynthetic process GO:0042089 3 0.011
mapk cascade GO:0000165 140 0.011
ribonucleoside monophosphate metabolic process GO:0009161 88 0.011
axon development GO:0061564 96 0.011
regulation of peptide transport GO:0090087 87 0.011
positive regulation of cell projection organization GO:0031346 111 0.011
positive regulation of cell death GO:0010942 184 0.011
regulation of body fluid levels GO:0050878 90 0.011
growth GO:0040007 165 0.011
response to radiation GO:0009314 137 0.011
negative regulation of catalytic activity GO:0043086 103 0.011
response to electrical stimulus GO:0051602 56 0.011
response to purine containing compound GO:0014074 126 0.011
peptide transport GO:0015833 97 0.011
response to hydrogen peroxide GO:0042542 89 0.011
anterior posterior pattern specification GO:0009952 1 0.011
single organism carbohydrate metabolic process GO:0044723 118 0.011
positive regulation of nucleotide metabolic process GO:0045981 91 0.011
protein transport GO:0015031 132 0.011
regulation of cellular catabolic process GO:0031329 101 0.011
organic acid transport GO:0015849 116 0.011
negative regulation of transport GO:0051051 136 0.011
gonad development GO:0008406 104 0.010
actin filament based process GO:0030029 86 0.010
establishment of protein localization GO:0045184 141 0.010
response to mechanical stimulus GO:0009612 134 0.010
regulation of bmp signaling pathway GO:0030510 2 0.010
regulation of response to wounding GO:1903034 69 0.010
chromosome segregation GO:0007059 2 0.010
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.010
regulation of protein modification process GO:0031399 194 0.010
spermatogenesis GO:0007283 99 0.010
cellular calcium ion homeostasis GO:0006874 160 0.010
regulation of nucleotide catabolic process GO:0030811 65 0.010
response to temperature stimulus GO:0009266 94 0.010
negative regulation of canonical wnt signaling pathway GO:0090090 4 0.010
formation of primary germ layer GO:0001704 1 0.010
purine containing compound biosynthetic process GO:0072522 85 0.010
regulation of muscle system process GO:0090257 79 0.010
mesoderm development GO:0007498 2 0.010
small molecule biosynthetic process GO:0044283 124 0.010
generation of precursor metabolites and energy GO:0006091 62 0.010
ribonucleotide catabolic process GO:0009261 136 0.010
cellular response to external stimulus GO:0071496 118 0.010

P4ha2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.026
nervous system disease DOID:863 0 0.026
central nervous system disease DOID:331 0 0.013
musculoskeletal system disease DOID:17 0 0.011
sensory system disease DOID:0050155 0 0.011