Rattus norvegicus

0 known processes

Trib3

tribbles homolog 3 (Drosophila)

(Aliases: NIPK)

Trib3 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
regulation of nucleic acid templated transcription GO:1903506 380 0.105
Human Mouse
response to nutrient GO:0007584 248 0.077
cation transport GO:0006812 382 0.072
transcription dna templated GO:0006351 377 0.069
Human
regulation of transcription dna templated GO:0006355 374 0.065
Human
nucleic acid templated transcription GO:0097659 379 0.062
Human Mouse
transcription from rna polymerase ii promoter GO:0006366 252 0.062
regulation of rna metabolic process GO:0051252 391 0.061
Human Mouse
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.057
cellular catabolic process GO:0044248 295 0.049
Fly
intracellular signal transduction GO:0035556 314 0.048
Human
reproductive process GO:0022414 372 0.045
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.045
response to cytokine GO:0034097 215 0.044
regulation of rna biosynthetic process GO:2001141 381 0.044
Human Mouse
response to nutrient levels GO:0031667 370 0.043
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.043
response to toxic substance GO:0009636 133 0.042
cellular response to endogenous stimulus GO:0071495 377 0.042
Mouse
transmembrane transport GO:0055085 412 0.041
regulation of hormone levels GO:0010817 187 0.041
response to extracellular stimulus GO:0009991 380 0.040
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.039
response to light stimulus GO:0009416 52 0.038
rna metabolic process GO:0016070 406 0.038
Human Mouse
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.037
Human
anion transmembrane transport GO:0098656 77 0.037
response to ketone GO:1901654 182 0.037
regulation of cell differentiation GO:0045595 320 0.036
Mouse
response to hypoxia GO:0001666 231 0.036
catabolic process GO:0009056 351 0.036
Fly
anion transport GO:0006820 178 0.035
lipid metabolic process GO:0006629 283 0.035
Mouse
response to inorganic substance GO:0010035 377 0.034
carbohydrate derivative metabolic process GO:1901135 346 0.034
carboxylic acid metabolic process GO:0019752 289 0.034
Mouse
regulation of secretion GO:0051046 224 0.031
amino acid transmembrane transport GO:0003333 33 0.031
cellular response to nitrogen compound GO:1901699 210 0.030
Mouse
positive regulation of nucleic acid templated transcription GO:1903508 197 0.030
nucleobase containing small molecule metabolic process GO:0055086 316 0.030
cellular component assembly GO:0022607 360 0.029
negative regulation of macromolecule metabolic process GO:0010605 260 0.029
Human Mouse
response to purine containing compound GO:0014074 126 0.029
negative regulation of metabolic process GO:0009892 331 0.028
Human Mouse
ion transmembrane transport GO:0034220 365 0.027
regulation of catalytic activity GO:0050790 304 0.027
Human Mouse
rhythmic process GO:0048511 156 0.027
response to metal ion GO:0010038 253 0.027
rna biosynthetic process GO:0032774 380 0.027
Human Mouse
cellular response to stress GO:0033554 269 0.027
Human
alpha amino acid metabolic process GO:1901605 71 0.027
g protein coupled receptor signaling pathway GO:0007186 242 0.027
response to radiation GO:0009314 137 0.026
cellular response to hormone stimulus GO:0032870 247 0.026
Mouse
oxidation reduction process GO:0055114 304 0.026
negative regulation of transcription dna templated GO:0045892 116 0.025
Human
oxoacid metabolic process GO:0043436 290 0.025
Mouse
organophosphate metabolic process GO:0019637 370 0.025
hexose metabolic process GO:0019318 58 0.025
nitrogen compound transport GO:0071705 229 0.025
regulation of apoptotic process GO:0042981 335 0.025
negative regulation of cellular metabolic process GO:0031324 281 0.025
Human Mouse
secretion by cell GO:0032940 248 0.025
negative regulation of cellular biosynthetic process GO:0031327 161 0.025
Human Mouse
positive regulation of transcription dna templated GO:0045893 197 0.024
positive regulation of biosynthetic process GO:0009891 319 0.024
carbohydrate metabolic process GO:0005975 130 0.024
purine containing compound metabolic process GO:0072521 253 0.024
cellular homeostasis GO:0019725 252 0.024
regulation of molecular function GO:0065009 398 0.023
Human Mouse
central nervous system development GO:0007417 311 0.023
regulation of cellular localization GO:0060341 263 0.023
carboxylic acid transport GO:0046942 115 0.023
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.023
Human Mouse
programmed cell death GO:0012501 392 0.023
Human
multi organism reproductive process GO:0044703 262 0.023
nucleoside metabolic process GO:0009116 179 0.022
negative regulation of rna metabolic process GO:0051253 123 0.022
Human Mouse
purine nucleotide metabolic process GO:0006163 229 0.022
negative regulation of nucleic acid templated transcription GO:1903507 117 0.022
Human Mouse
head development GO:0060322 247 0.022
positive regulation of cellular biosynthetic process GO:0031328 295 0.022
negative regulation of biosynthetic process GO:0009890 168 0.022
Human Mouse
regulation of signal transduction GO:0009966 318 0.022
Human
nucleotide metabolic process GO:0009117 279 0.022
positive regulation of rna biosynthetic process GO:1902680 197 0.022
purine ribonucleotide metabolic process GO:0009150 227 0.022
response to other organism GO:0051707 220 0.021
steroid metabolic process GO:0008202 73 0.021
l alpha amino acid transmembrane transport GO:1902475 15 0.021
circadian rhythm GO:0007623 88 0.021
response to estrogen GO:0043627 232 0.021
macromolecular complex assembly GO:0065003 273 0.021
cation transmembrane transport GO:0098655 263 0.021
cellular ketone metabolic process GO:0042180 51 0.021
Mouse
branched chain amino acid transport GO:0015803 2 0.021
nucleoside phosphate metabolic process GO:0006753 283 0.021
negative regulation of signaling GO:0023057 157 0.021
reproduction GO:0000003 245 0.021
organic acid metabolic process GO:0006082 292 0.021
Mouse
neuron differentiation GO:0030182 368 0.021
cellular chemical homeostasis GO:0055082 247 0.021
single organism biosynthetic process GO:0044711 342 0.020
Mouse
negative regulation of gene expression GO:0010629 199 0.020
Human
positive regulation of gene expression GO:0010628 244 0.020
small gtpase mediated signal transduction GO:0007264 36 0.020
protein homooligomerization GO:0051260 91 0.020
axis specification GO:0009798 4 0.020
organonitrogen compound catabolic process GO:1901565 179 0.019
response to decreased oxygen levels GO:0036293 237 0.019
regulation of cell development GO:0060284 263 0.019
organic substance catabolic process GO:1901575 316 0.019
Fly
purine nucleoside triphosphate metabolic process GO:0009144 141 0.019
metal ion homeostasis GO:0055065 186 0.019
small molecule biosynthetic process GO:0044283 124 0.019
Mouse
heterocycle catabolic process GO:0046700 167 0.018
multicellular organismal reproductive process GO:0048609 233 0.018
monosaccharide metabolic process GO:0005996 61 0.018
negative regulation of cell development GO:0010721 82 0.018
ribonucleotide metabolic process GO:0009259 231 0.017
regulation of phosphorus metabolic process GO:0051174 349 0.017
Human Mouse
neuron development GO:0048666 286 0.017
response to corticosterone GO:0051412 40 0.017
negative regulation of cell death GO:0060548 229 0.017
developmental process involved in reproduction GO:0003006 159 0.017
negative regulation of programmed cell death GO:0043069 183 0.017
single organism catabolic process GO:0044712 283 0.017
cellular response to organonitrogen compound GO:0071417 197 0.017
Mouse
glucose metabolic process GO:0006006 52 0.017
cellular cation homeostasis GO:0030003 180 0.017
positive regulation of molecular function GO:0044093 230 0.017
Mouse
glycosyl compound metabolic process GO:1901657 182 0.017
hormone metabolic process GO:0042445 69 0.017
negative regulation of apoptotic process GO:0043066 181 0.017
regulation of programmed cell death GO:0043067 341 0.016
cellular response to cytokine stimulus GO:0071345 127 0.016
sexual reproduction GO:0019953 148 0.016
response to alkaloid GO:0043279 132 0.016
regulation of phosphate metabolic process GO:0019220 349 0.016
Human Mouse
amino acid transport GO:0006865 70 0.016
organic cyclic compound catabolic process GO:1901361 175 0.016
nucleobase containing compound catabolic process GO:0034655 152 0.016
establishment of protein localization GO:0045184 141 0.016
regulation of cellular protein metabolic process GO:0032268 267 0.016
Human Mouse Fly
multicellular organism reproduction GO:0032504 233 0.016
cellular amine metabolic process GO:0044106 38 0.016
reproductive system development GO:0061458 128 0.016
aromatic compound catabolic process GO:0019439 168 0.016
positive regulation of cellular catabolic process GO:0031331 71 0.016
Fly
organ regeneration GO:0031100 101 0.016
ribonucleoside metabolic process GO:0009119 174 0.016
multicellular organism growth GO:0035264 1 0.016
metal ion transport GO:0030001 289 0.016
lipid biosynthetic process GO:0008610 128 0.016
Mouse
protein complex biogenesis GO:0070271 263 0.016
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.015
response to insulin GO:0032868 133 0.015
Mouse
regulation of protein metabolic process GO:0051246 289 0.015
Human Mouse Fly
single organism carbohydrate metabolic process GO:0044723 118 0.015
positive regulation of cell death GO:0010942 184 0.015
response to vitamin GO:0033273 131 0.015
negative regulation of transport GO:0051051 136 0.015
positive regulation of apoptotic process GO:0043065 154 0.015
energy derivation by oxidation of organic compounds GO:0015980 46 0.015
apoptotic process GO:0006915 381 0.015
Human
regeneration GO:0031099 163 0.015
single organism reproductive process GO:0044702 297 0.015
secretion GO:0046903 307 0.015
protein phosphorylation GO:0006468 345 0.015
Human Mouse
response to oxygen levels GO:0070482 265 0.015
macromolecular complex subunit organization GO:0043933 339 0.015
cellular divalent inorganic cation homeostasis GO:0072503 162 0.014
response to estradiol GO:0032355 164 0.014
hormone secretion GO:0046879 115 0.014
regulation of nervous system development GO:0051960 264 0.014
regulation of intracellular signal transduction GO:1902531 218 0.014
Human
cofactor metabolic process GO:0051186 95 0.014
organic anion transport GO:0015711 132 0.014
response to acid chemical GO:0001101 222 0.014
cellular ion homeostasis GO:0006873 184 0.014
negative regulation of multicellular organismal process GO:0051241 203 0.014
cellular component biogenesis GO:0044085 368 0.014
regulation of purine nucleotide metabolic process GO:1900542 115 0.014
positive regulation of transport GO:0051050 245 0.014
purine ribonucleoside triphosphate metabolic process GO:0009205 140 0.014
brain development GO:0007420 247 0.014
protein oligomerization GO:0051259 191 0.014
positive regulation of multicellular organismal process GO:0051240 387 0.014
reactive oxygen species biosynthetic process GO:1903409 8 0.014
carbohydrate derivative catabolic process GO:1901136 147 0.014
cellular response to oxygen containing compound GO:1901701 386 0.013
Mouse
macromolecule localization GO:0033036 252 0.013
regulation of cellular ketone metabolic process GO:0010565 27 0.013
Mouse
generation of precursor metabolites and energy GO:0006091 62 0.013
positive regulation of neurogenesis GO:0050769 165 0.013
ribose phosphate metabolic process GO:0019693 235 0.013
cellular hormone metabolic process GO:0034754 49 0.013
reproductive structure development GO:0048608 128 0.013
response to camp GO:0051591 91 0.013
gland development GO:0048732 155 0.013
divalent inorganic cation homeostasis GO:0072507 165 0.013
chemical homeostasis GO:0048878 292 0.013
purine nucleotide catabolic process GO:0006195 136 0.013
purine nucleoside metabolic process GO:0042278 169 0.013
ribonucleoside catabolic process GO:0042454 126 0.013
cellular amino acid metabolic process GO:0006520 107 0.013
ras protein signal transduction GO:0007265 29 0.013
regulation of catabolic process GO:0009894 113 0.013
Fly
regulation of neuron projection development GO:0010975 161 0.013
response to peptide GO:1901652 292 0.012
Mouse
protein localization GO:0008104 191 0.012
cellular metal ion homeostasis GO:0006875 172 0.012
response to ammonium ion GO:0060359 71 0.012
negative regulation of catalytic activity GO:0043086 103 0.012
Human Mouse
regulation of neuron differentiation GO:0045664 208 0.012
ion homeostasis GO:0050801 212 0.012
reactive nitrogen species metabolic process GO:2001057 1 0.012
reactive oxygen species metabolic process GO:0072593 37 0.012
amide transport GO:0042886 105 0.012
response to oxidative stress GO:0006979 186 0.012
positive regulation of hydrolase activity GO:0051345 86 0.012
sulfur compound metabolic process GO:0006790 70 0.012
regulation of secretion by cell GO:1903530 208 0.012
regulation of phosphorylation GO:0042325 248 0.012
Human Mouse
positive regulation of response to stimulus GO:0048584 285 0.012
cellular macromolecule localization GO:0070727 122 0.012
hormone transport GO:0009914 121 0.012
regulation of gtpase activity GO:0043087 57 0.012
synaptic growth at neuromuscular junction GO:0051124 1 0.012
regulation of cellular amino acid metabolic process GO:0006521 2 0.012
coenzyme metabolic process GO:0006732 86 0.012
cellular response to alcohol GO:0097306 87 0.012
positive regulation of secretion by cell GO:1903532 128 0.012
negative regulation of rna biosynthetic process GO:1902679 118 0.011
Human Mouse
negative regulation of transcription from rna polymerase ii promoter GO:0000122 75 0.011
response to glucocorticoid GO:0051384 223 0.011
positive regulation of cell development GO:0010720 176 0.011
cell cycle GO:0007049 101 0.011
Fly
protein complex assembly GO:0006461 263 0.011
organophosphate biosynthetic process GO:0090407 143 0.011
purine ribonucleotide catabolic process GO:0009154 136 0.011
regulation of cellular amine metabolic process GO:0033238 8 0.011
purine ribonucleoside metabolic process GO:0046128 168 0.011
glycogen metabolic process GO:0005977 23 0.011
defense response GO:0006952 194 0.011
positive regulation of purine nucleotide metabolic process GO:1900544 91 0.011
regulation of multicellular organismal development GO:2000026 376 0.011
purine containing compound catabolic process GO:0072523 138 0.011
heart morphogenesis GO:0003007 3 0.011
peptide hormone secretion GO:0030072 84 0.011
organelle organization GO:0006996 266 0.011
Fly
response to hexose GO:0009746 144 0.011
cation homeostasis GO:0055080 195 0.011
cellular glucan metabolic process GO:0006073 23 0.011
cellular response to organic cyclic compound GO:0071407 202 0.011
response to monosaccharide GO:0034284 159 0.011
regulation of nucleotide metabolic process GO:0006140 117 0.011
locomotor rhythm GO:0045475 1 0.011
regulation of nucleotide catabolic process GO:0030811 65 0.011
neurological system process GO:0050877 219 0.011
nucleoside triphosphate metabolic process GO:0009141 144 0.011
regulation of neurogenesis GO:0050767 247 0.011
response to temperature stimulus GO:0009266 94 0.011
cellular protein localization GO:0034613 122 0.011
maintenance of location GO:0051235 17 0.011
multi multicellular organism process GO:0044706 138 0.011
tissue development GO:0009888 252 0.011
positive regulation of nervous system development GO:0051962 178 0.011
peptide transport GO:0015833 97 0.010
steroid biosynthetic process GO:0006694 48 0.010
amine metabolic process GO:0009308 38 0.010
chromosome segregation GO:0007059 2 0.010
divalent inorganic cation transport GO:0072511 134 0.010
bmp signaling pathway GO:0030509 4 0.010
negative regulation of response to stimulus GO:0048585 155 0.010
blood circulation GO:0008015 183 0.010
negative regulation of cell communication GO:0010648 158 0.010
cellular nitrogen compound catabolic process GO:0044270 163 0.010
conditioned taste aversion GO:0001661 2 0.010
negative regulation of cell differentiation GO:0045596 99 0.010
Mouse
regulation of purine nucleotide catabolic process GO:0033121 65 0.010
cell redox homeostasis GO:0045454 1 0.010
regulation of fat cell differentiation GO:0045598 3 0.010
Mouse
regulation of reactive oxygen species biosynthetic process GO:1903426 5 0.010
regulation of hydrolase activity GO:0051336 143 0.010
leucine transport GO:0015820 2 0.010
development of primary sexual characteristics GO:0045137 107 0.010
behavior GO:0007610 205 0.010
regulation of synaptic transmission GO:0050804 141 0.010
response to organophosphorus GO:0046683 102 0.010
positive regulation of nucleotide metabolic process GO:0045981 91 0.010
mesoderm development GO:0007498 2 0.010
positive regulation of cellular amine metabolic process GO:0033240 3 0.010
glucan metabolic process GO:0044042 23 0.010

Trib3 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
sensory system disease DOID:0050155 0 0.031
disease of anatomical entity DOID:7 0 0.031
eye and adnexa disease DOID:1492 0 0.031
nervous system disease DOID:863 0 0.031
eye disease DOID:5614 0 0.014
disease of metabolism DOID:0014667 0 0.014
myopathy DOID:423 0 0.012
muscular disease DOID:0080000 0 0.012
musculoskeletal system disease DOID:17 0 0.012
muscle tissue disease DOID:66 0 0.012
inherited metabolic disorder DOID:655 0 0.011