Rattus norvegicus

0 known processes

Appl1

adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1

(Aliases: RGD1309388)

Appl1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
regulation of protein metabolic process GO:0051246 289 0.227
regulation of molecular function GO:0065009 398 0.118
positive regulation of biosynthetic process GO:0009891 319 0.117
intracellular signal transduction GO:0035556 314 0.105
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.090
regulation of cell proliferation GO:0042127 359 0.090
nucleoside phosphate metabolic process GO:0006753 283 0.085
regulation of rna biosynthetic process GO:2001141 381 0.084
heterocycle catabolic process GO:0046700 167 0.074
protein complex assembly GO:0006461 263 0.072
macromolecular complex assembly GO:0065003 273 0.071
protein complex subunit organization GO:0071822 302 0.068
organelle organization GO:0006996 266 0.067
regulation of cellular protein metabolic process GO:0032268 267 0.066
regulation of nucleic acid templated transcription GO:1903506 380 0.066
nucleic acid templated transcription GO:0097659 379 0.062
cellular component assembly GO:0022607 360 0.061
positive regulation of phosphate metabolic process GO:0045937 262 0.061
regulation of rna metabolic process GO:0051252 391 0.060
regulation of apoptotic process GO:0042981 335 0.060
protein localization GO:0008104 191 0.059
Human
transcription dna templated GO:0006351 377 0.059
anterior posterior pattern specification GO:0009952 1 0.056
purine ribonucleotide metabolic process GO:0009150 227 0.055
cellular component biogenesis GO:0044085 368 0.054
cytoskeleton organization GO:0007010 111 0.053
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.052
positive regulation of cell proliferation GO:0008284 249 0.052
organonitrogen compound catabolic process GO:1901565 179 0.050
transcription from rna polymerase ii promoter GO:0006366 252 0.049
organic acid metabolic process GO:0006082 292 0.049
purine containing compound catabolic process GO:0072523 138 0.049
apoptotic process GO:0006915 381 0.047
oxoacid metabolic process GO:0043436 290 0.046
response to peptide GO:1901652 292 0.046
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.043
regulation of transcription dna templated GO:0006355 374 0.042
regulation of catalytic activity GO:0050790 304 0.041
neurological system process GO:0050877 219 0.041
positive regulation of phosphorus metabolic process GO:0010562 262 0.040
macromolecular complex subunit organization GO:0043933 339 0.040
positive regulation of rna biosynthetic process GO:1902680 197 0.040
protein complex biogenesis GO:0070271 263 0.040
positive regulation of catalytic activity GO:0043085 184 0.040
purine containing compound metabolic process GO:0072521 253 0.039
rna biosynthetic process GO:0032774 380 0.039
rna metabolic process GO:0016070 406 0.038
regulation of phosphate metabolic process GO:0019220 349 0.038
positive regulation of cellular biosynthetic process GO:0031328 295 0.038
positive regulation of molecular function GO:0044093 230 0.037
catabolic process GO:0009056 351 0.036
cellular response to hormone stimulus GO:0032870 247 0.036
positive regulation of gene expression GO:0010628 244 0.035
regulation of signal transduction GO:0009966 318 0.034
glycosyl compound metabolic process GO:1901657 182 0.034
purine ribonucleotide catabolic process GO:0009154 136 0.033
cellular component movement GO:0006928 248 0.033
cellular catabolic process GO:0044248 295 0.032
positive regulation of multicellular organismal process GO:0051240 387 0.032
nucleobase containing compound catabolic process GO:0034655 152 0.031
regulation of cellular amino acid metabolic process GO:0006521 2 0.031
positive regulation of nucleic acid templated transcription GO:1903508 197 0.031
nucleotide metabolic process GO:0009117 279 0.031
carbohydrate derivative catabolic process GO:1901136 147 0.030
positive regulation of rna metabolic process GO:0051254 203 0.030
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.030
organ regeneration GO:0031100 101 0.030
regulation of cellular localization GO:0060341 263 0.030
Human
positive regulation of cellular protein metabolic process GO:0032270 167 0.029
organic substance catabolic process GO:1901575 316 0.029
cellular protein complex assembly GO:0043623 44 0.029
positive regulation of cellular component organization GO:0051130 200 0.028
localization of cell GO:0051674 202 0.028
cell migration GO:0016477 197 0.028
regulation of cellular amine metabolic process GO:0033238 8 0.028
carbohydrate derivative metabolic process GO:1901135 346 0.028
cellular nitrogen compound catabolic process GO:0044270 163 0.028
anatomical structure morphogenesis GO:0009653 298 0.027
nucleoside metabolic process GO:0009116 179 0.027
nucleoside triphosphate catabolic process GO:0009143 123 0.026
negative regulation of metabolic process GO:0009892 331 0.026
regulation of secretion GO:0051046 224 0.026
nucleoside catabolic process GO:0009164 126 0.026
cell projection organization GO:0030030 302 0.026
purine ribonucleoside triphosphate metabolic process GO:0009205 140 0.026
programmed cell death GO:0012501 392 0.025
positive regulation of transcription dna templated GO:0045893 197 0.025
regulation of catabolic process GO:0009894 113 0.025
nucleobase containing small molecule metabolic process GO:0055086 316 0.025
cellular response to endogenous stimulus GO:0071495 377 0.025
cell motility GO:0048870 202 0.025
negative regulation of macromolecule metabolic process GO:0010605 260 0.025
organophosphate metabolic process GO:0019637 370 0.025
purine nucleotide metabolic process GO:0006163 229 0.025
positive regulation of phosphorylation GO:0042327 177 0.025
negative regulation of cellular metabolic process GO:0031324 281 0.025
regulation of phosphorus metabolic process GO:0051174 349 0.025
multicellular organism reproduction GO:0032504 233 0.025
single organism reproductive process GO:0044702 297 0.025
cellular amine metabolic process GO:0044106 38 0.024
nucleoside phosphate catabolic process GO:1901292 140 0.024
axis specification GO:0009798 4 0.024
aromatic compound catabolic process GO:0019439 168 0.024
ribose phosphate metabolic process GO:0019693 235 0.024
chromosome segregation GO:0007059 2 0.023
developmental process involved in reproduction GO:0003006 159 0.023
growth GO:0040007 165 0.023
regulation of system process GO:0044057 208 0.023
cellular macromolecular complex assembly GO:0034622 58 0.023
ribonucleotide metabolic process GO:0009259 231 0.022
positive regulation of protein metabolic process GO:0051247 178 0.022
protein phosphorylation GO:0006468 345 0.022
amine metabolic process GO:0009308 38 0.022
positive regulation of organelle organization GO:0010638 48 0.022
protein targeting GO:0006605 61 0.022
ribonucleoside catabolic process GO:0042454 126 0.022
response to cytokine GO:0034097 215 0.022
regulation of cell migration GO:0030334 128 0.021
cell cell signaling GO:0007267 335 0.021
central nervous system development GO:0007417 311 0.021
response to peptide hormone GO:0043434 278 0.021
regulation of cellular component organization GO:0051128 368 0.021
Human
response to glucocorticoid GO:0051384 223 0.021
response to decreased oxygen levels GO:0036293 237 0.021
response to wounding GO:0009611 254 0.021
nucleoside triphosphate metabolic process GO:0009141 144 0.020
synaptic transmission GO:0007268 235 0.020
regulation of protein phosphorylation GO:0001932 183 0.020
response to oxygen levels GO:0070482 265 0.020
purine ribonucleoside metabolic process GO:0046128 168 0.020
positive regulation of secretion GO:0051047 140 0.020
behavior GO:0007610 205 0.020
cellular response to oxygen containing compound GO:1901701 386 0.020
regulation of secretion by cell GO:1903530 208 0.020
regulation of multicellular organismal development GO:2000026 376 0.020
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.020
ribonucleoside triphosphate catabolic process GO:0009203 122 0.019
organic cyclic compound catabolic process GO:1901361 175 0.019
response to estrogen GO:0043627 232 0.019
positive regulation of kinase activity GO:0033674 77 0.019
purine nucleoside metabolic process GO:0042278 169 0.019
memory GO:0007613 54 0.019
reproduction GO:0000003 245 0.019
cell cycle GO:0007049 101 0.019
regulation of anatomical structure size GO:0090066 135 0.018
cellular response to nitrogen compound GO:1901699 210 0.018
negative regulation of biosynthetic process GO:0009890 168 0.018
positive regulation of transcription factor import into nucleus GO:0042993 4 0.018
male mating behavior GO:0060179 3 0.018
ras protein signal transduction GO:0007265 29 0.018
nucleotide catabolic process GO:0009166 139 0.018
cell cycle process GO:0022402 57 0.018
single organism cellular localization GO:1902580 102 0.018
Human
cellular response to peptide GO:1901653 133 0.017
positive regulation of transport GO:0051050 245 0.017
regulation of membrane potential GO:0042391 110 0.017
negative regulation of cell proliferation GO:0008285 119 0.017
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.017
positive regulation of protein phosphorylation GO:0001934 135 0.017
regulation of purine nucleotide metabolic process GO:1900542 115 0.017
embryonic pattern specification GO:0009880 1 0.017
positive regulation of cellular amine metabolic process GO:0033240 3 0.017
regulation of protein kinase activity GO:0045859 105 0.017
regulation of cellular component movement GO:0051270 150 0.016
carboxylic acid metabolic process GO:0019752 289 0.016
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.016
response to extracellular stimulus GO:0009991 380 0.016
regulation of cell projection organization GO:0031344 175 0.016
actin cytoskeleton organization GO:0030036 73 0.016
purine nucleoside triphosphate catabolic process GO:0009146 122 0.016
positive regulation of cellular component biogenesis GO:0044089 55 0.016
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.016
purine nucleoside catabolic process GO:0006152 124 0.015
negative regulation of protein metabolic process GO:0051248 114 0.015
purine nucleotide catabolic process GO:0006195 136 0.015
gtp catabolic process GO:0006184 71 0.015
response to radiation GO:0009314 137 0.015
negative regulation of cell differentiation GO:0045596 99 0.015
neuron projection development GO:0031175 273 0.015
positive regulation of developmental process GO:0051094 283 0.015
cell morphogenesis GO:0000902 142 0.015
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.015
cellular amino acid metabolic process GO:0006520 107 0.015
regulation of cell cycle GO:0051726 73 0.015
purine nucleoside triphosphate metabolic process GO:0009144 141 0.014
single organism organelle organization GO:1902589 180 0.014
regulation of hydrolase activity GO:0051336 143 0.014
synaptic growth at neuromuscular junction GO:0051124 1 0.014
positive regulation of nucleotide metabolic process GO:0045981 91 0.014
embryonic axis specification GO:0000578 1 0.014
purine ribonucleoside catabolic process GO:0046130 124 0.014
regulation of cellular ketone metabolic process GO:0010565 27 0.014
positive regulation of secretion by cell GO:1903532 128 0.014
reproductive process GO:0022414 372 0.014
regulation of cell development GO:0060284 263 0.014
negative regulation of apoptotic process GO:0043066 181 0.014
actin filament based process GO:0030029 86 0.014
regulation of locomotion GO:0040012 148 0.014
regulation of cell motility GO:2000145 131 0.014
aging GO:0007568 241 0.014
neuron differentiation GO:0030182 368 0.014
ribonucleoside metabolic process GO:0009119 174 0.013
cellular protein localization GO:0034613 122 0.013
Human
neuronal action potential GO:0019228 35 0.013
establishment of organelle localization GO:0051656 37 0.013
negative regulation of cellular protein metabolic process GO:0032269 106 0.013
centrosome cycle GO:0007098 1 0.013
bmp signaling pathway GO:0030509 4 0.013
regulation of intracellular signal transduction GO:1902531 218 0.013
microtubule based process GO:0007017 36 0.013
single organism biosynthetic process GO:0044711 342 0.013
regulation of cytoskeleton organization GO:0051493 49 0.013
negative regulation of multicellular organismal process GO:0051241 203 0.013
single organism catabolic process GO:0044712 283 0.013
regulation of protein modification process GO:0031399 194 0.013
response to carbohydrate GO:0009743 183 0.013
g protein coupled receptor signaling pathway GO:0007186 242 0.013
response to ketone GO:1901654 182 0.013
gamete generation GO:0007276 124 0.013
sexual reproduction GO:0019953 148 0.013
locomotion GO:0040011 237 0.013
glycosyl compound catabolic process GO:1901658 126 0.013
positive regulation of neurogenesis GO:0050769 165 0.012
positive regulation of apoptotic process GO:0043065 154 0.012
small molecule biosynthetic process GO:0044283 124 0.012
multicellular organismal signaling GO:0035637 44 0.012
regulation of smooth muscle cell proliferation GO:0048660 75 0.012
neuron development GO:0048666 286 0.012
negative regulation of response to stimulus GO:0048585 155 0.012
positive regulation of cell communication GO:0010647 271 0.012
response to hypoxia GO:0001666 231 0.012
positive regulation of smooth muscle cell proliferation GO:0048661 51 0.012
response to nutrient levels GO:0031667 370 0.012
organophosphate catabolic process GO:0046434 148 0.012
regulation of mapk cascade GO:0043408 116 0.012
regulation of phosphorylation GO:0042325 248 0.012
positive regulation of signaling GO:0023056 270 0.012
transmission of nerve impulse GO:0019226 42 0.012
multi organism reproductive process GO:0044703 262 0.012
regulation of cell morphogenesis GO:0022604 77 0.012
cellular ketone metabolic process GO:0042180 51 0.012
rna localization GO:0006403 4 0.012
positive regulation of hydrolase activity GO:0051345 86 0.012
intracellular transport GO:0046907 185 0.012
meiotic cell cycle process GO:1903046 3 0.012
centrosome organization GO:0051297 1 0.012
cytoplasmic transport GO:0016482 115 0.011
positive regulation of protein modification process GO:0031401 142 0.011
brain development GO:0007420 247 0.011
small gtpase mediated signal transduction GO:0007264 36 0.011
regulation of cellular component biogenesis GO:0044087 86 0.011
regulation of alternative mrna splicing via spliceosome GO:0000381 2 0.011
positive regulation of cell death GO:0010942 184 0.011
signal transduction by phosphorylation GO:0023014 144 0.011
olfactory learning GO:0008355 1 0.011
single organism behavior GO:0044708 130 0.011
proteolysis GO:0006508 175 0.011
regulation of growth GO:0040008 105 0.011
muscle cell proliferation GO:0033002 84 0.011
response to hexose GO:0009746 144 0.011
protein oligomerization GO:0051259 191 0.011
cell adhesion GO:0007155 110 0.011
response to corticosteroid GO:0031960 235 0.011
negative regulation of signaling GO:0023057 157 0.011
cellular response to cytokine stimulus GO:0071345 127 0.011
spindle organization GO:0007051 2 0.011
regulation of cellular component size GO:0032535 51 0.011
dendrite development GO:0016358 72 0.011
regulation of organelle organization GO:0033043 80 0.011
negative regulation of neurogenesis GO:0050768 78 0.011
olfactory behavior GO:0042048 2 0.010
regulation of nervous system development GO:0051960 264 0.010
negative regulation of cell development GO:0010721 82 0.010
nitrogen compound transport GO:0071705 229 0.010
multicellular organismal reproductive process GO:0048609 233 0.010
ribonucleoside triphosphate metabolic process GO:0009199 141 0.010
negative regulation of cell communication GO:0010648 158 0.010
regeneration GO:0031099 163 0.010
positive regulation of cytoskeleton organization GO:0051495 26 0.010
regulation of kinase activity GO:0043549 117 0.010
regulation of transferase activity GO:0051338 123 0.010
developmental growth GO:0048589 100 0.010
cellular response to peptide hormone stimulus GO:0071375 120 0.010
nucleosome organization GO:0034728 1 0.010
learning or memory GO:0007611 90 0.010
regulation of anatomical structure morphogenesis GO:0022603 141 0.010
positive regulation of programmed cell death GO:0043068 157 0.010

Appl1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.010
nervous system disease DOID:863 0 0.010