Rattus norvegicus

0 known processes

Smoc2

SPARC related modular calcium binding 2

Smoc2 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
cellular response to organic cyclic compound GO:0071407 202 0.139
cellular response to endogenous stimulus GO:0071495 377 0.108
response to corticosteroid GO:0031960 235 0.082
response to nutrient levels GO:0031667 370 0.081
response to estrogen GO:0043627 232 0.081
tissue development GO:0009888 252 0.079
response to acid chemical GO:0001101 222 0.071
response to extracellular stimulus GO:0009991 380 0.071
cellular response to oxygen containing compound GO:1901701 386 0.070
anatomical structure morphogenesis GO:0009653 298 0.070
cellular catabolic process GO:0044248 295 0.067
cardiovascular system development GO:0072358 134 0.067
organ regeneration GO:0031100 101 0.065
catabolic process GO:0009056 351 0.061
protein complex subunit organization GO:0071822 302 0.054
response to peptide hormone GO:0043434 278 0.047
response to inorganic substance GO:0010035 377 0.046
response to glucocorticoid GO:0051384 223 0.046
nucleoside phosphate metabolic process GO:0006753 283 0.045
regulation of multicellular organismal development GO:2000026 376 0.044
cellular component assembly GO:0022607 360 0.044
response to estradiol GO:0032355 164 0.044
cellular response to lipid GO:0071396 201 0.044
macromolecular complex subunit organization GO:0043933 339 0.044
carbohydrate derivative metabolic process GO:1901135 346 0.043
organic acid metabolic process GO:0006082 292 0.043
response to oxidative stress GO:0006979 186 0.041
regeneration GO:0031099 163 0.040
homeostatic process GO:0042592 331 0.040
biological adhesion GO:0022610 110 0.040
Mouse
rna biosynthetic process GO:0032774 380 0.040
cellular component biogenesis GO:0044085 368 0.038
wound healing GO:0042060 122 0.038
cell adhesion GO:0007155 110 0.038
Mouse
cellular response to stress GO:0033554 269 0.038
oxoacid metabolic process GO:0043436 290 0.038
aging GO:0007568 241 0.038
circulatory system development GO:0072359 134 0.037
limb morphogenesis GO:0035108 4 0.036
oxidation reduction process GO:0055114 304 0.036
central nervous system development GO:0007417 311 0.036
response to growth factor GO:0070848 189 0.036
regulation of cell differentiation GO:0045595 320 0.036
organ morphogenesis GO:0009887 75 0.035
urogenital system development GO:0001655 78 0.035
single organism catabolic process GO:0044712 283 0.035
cellular response to hormone stimulus GO:0032870 247 0.034
neuron differentiation GO:0030182 368 0.034
carboxylic acid metabolic process GO:0019752 289 0.034
organic substance catabolic process GO:1901575 316 0.033
chemical homeostasis GO:0048878 292 0.033
head development GO:0060322 247 0.032
positive regulation of molecular function GO:0044093 230 0.032
cellular response to growth factor stimulus GO:0071363 162 0.032
positive regulation of developmental process GO:0051094 283 0.031
macromolecular complex assembly GO:0065003 273 0.031
response to oxygen levels GO:0070482 265 0.031
regulation of programmed cell death GO:0043067 341 0.031
skeletal system development GO:0001501 41 0.031
apoptotic process GO:0006915 381 0.031
response to vitamin GO:0033273 131 0.030
metal ion transport GO:0030001 289 0.030
brain development GO:0007420 247 0.030
sensory organ development GO:0007423 74 0.029
protein phosphorylation GO:0006468 345 0.029
regulation of molecular function GO:0065009 398 0.029
protein complex assembly GO:0006461 263 0.029
regulation of rna metabolic process GO:0051252 391 0.029
regulation of apoptotic process GO:0042981 335 0.028
wnt signaling pathway planar cell polarity pathway GO:0060071 2 0.028
cellular ketone metabolic process GO:0042180 51 0.028
positive regulation of cell differentiation GO:0045597 217 0.028
response to nutrient GO:0007584 248 0.027
cell projection organization GO:0030030 302 0.027
programmed cell death GO:0012501 392 0.027
hormone metabolic process GO:0042445 69 0.027
cation homeostasis GO:0055080 195 0.027
neuron development GO:0048666 286 0.027
regulation of cellular component organization GO:0051128 368 0.027
regulation of phosphorus metabolic process GO:0051174 349 0.027
ion transmembrane transport GO:0034220 365 0.027
organophosphate metabolic process GO:0019637 370 0.027
appendage morphogenesis GO:0035107 4 0.027
positive regulation of programmed cell death GO:0043068 157 0.027
response to monosaccharide GO:0034284 159 0.027
reproduction GO:0000003 245 0.026
cellular component movement GO:0006928 248 0.026
response to ketone GO:1901654 182 0.026
cellular response to organonitrogen compound GO:0071417 197 0.026
response to peptide GO:1901652 292 0.026
reproductive system development GO:0061458 128 0.026
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.026
neuron projection development GO:0031175 273 0.026
positive regulation of catalytic activity GO:0043085 184 0.026
epithelial cell proliferation GO:0050673 54 0.026
nucleic acid templated transcription GO:0097659 379 0.025
nucleotide metabolic process GO:0009117 279 0.025
regulation of cellular protein metabolic process GO:0032268 267 0.025
eye morphogenesis GO:0048592 4 0.025
regulation of immune system process GO:0002682 123 0.025
cell motility GO:0048870 202 0.025
positive regulation of multicellular organismal process GO:0051240 387 0.025
multicellular organismal reproductive process GO:0048609 233 0.025
positive regulation of cell proliferation GO:0008284 249 0.025
regulation of catalytic activity GO:0050790 304 0.024
ribose phosphate metabolic process GO:0019693 235 0.024
nucleobase containing small molecule metabolic process GO:0055086 316 0.024
cellular amino acid metabolic process GO:0006520 107 0.024
renal system development GO:0072001 67 0.024
cellular response to alcohol GO:0097306 87 0.024
liver development GO:0001889 90 0.024
endothelial cell proliferation GO:0001935 20 0.024
organic cyclic compound catabolic process GO:1901361 175 0.023
response to glucose GO:0009749 136 0.023
localization of cell GO:0051674 202 0.023
regulation of neurogenesis GO:0050767 247 0.023
nucleoside triphosphate catabolic process GO:0009143 123 0.023
regulation of nervous system development GO:0051960 264 0.023
response to decreased oxygen levels GO:0036293 237 0.023
regulation of canonical wnt signaling pathway GO:0060828 4 0.023
positive regulation of phosphorus metabolic process GO:0010562 262 0.023
ribonucleoside metabolic process GO:0009119 174 0.023
regulation of cell proliferation GO:0042127 359 0.022
cation transport GO:0006812 382 0.022
glycosyl compound metabolic process GO:1901657 182 0.022
secretion GO:0046903 307 0.022
regulation of cellular ketone metabolic process GO:0010565 27 0.022
blood vessel development GO:0001568 69 0.022
organonitrogen compound catabolic process GO:1901565 179 0.022
negative regulation of macromolecule metabolic process GO:0010605 260 0.022
regulation of cell development GO:0060284 263 0.022
purine nucleotide metabolic process GO:0006163 229 0.022
cellular amine metabolic process GO:0044106 38 0.022
transmembrane transport GO:0055085 412 0.022
multicellular organism reproduction GO:0032504 233 0.021
positive regulation of rna biosynthetic process GO:1902680 197 0.021
response to wounding GO:0009611 254 0.021
single organism reproductive process GO:0044702 297 0.021
multi organism reproductive process GO:0044703 262 0.021
intracellular signal transduction GO:0035556 314 0.021
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.021
tube development GO:0035295 89 0.021
angiogenesis GO:0001525 53 0.021
protein complex biogenesis GO:0070271 263 0.021
regulation of cellular amino acid metabolic process GO:0006521 2 0.021
positive regulation of response to stimulus GO:0048584 285 0.020
nucleoside phosphate catabolic process GO:1901292 140 0.020
regulation of phosphorylation GO:0042325 248 0.020
cell morphogenesis GO:0000902 142 0.020
purine containing compound metabolic process GO:0072521 253 0.020
positive regulation of gene expression GO:0010628 244 0.020
purine nucleoside metabolic process GO:0042278 169 0.020
cellular lipid metabolic process GO:0044255 208 0.020
sex differentiation GO:0007548 113 0.020
reproductive process GO:0022414 372 0.020
positive regulation of phosphate metabolic process GO:0045937 262 0.020
embryonic appendage morphogenesis GO:0035113 4 0.020
purine ribonucleotide metabolic process GO:0009150 227 0.019
positive regulation of signaling GO:0023056 270 0.019
gland development GO:0048732 155 0.019
amine metabolic process GO:0009308 38 0.019
positive regulation of biosynthetic process GO:0009891 319 0.019
heterocycle catabolic process GO:0046700 167 0.019
regulation of cell migration GO:0030334 128 0.019
regulation of protein metabolic process GO:0051246 289 0.019
response to radiation GO:0009314 137 0.019
positive regulation of protein metabolic process GO:0051247 178 0.018
response to hypoxia GO:0001666 231 0.018
regulation of neuron differentiation GO:0045664 208 0.018
immune system process GO:0002376 204 0.018
developmental process involved in reproduction GO:0003006 159 0.018
blood circulation GO:0008015 183 0.018
regulation of rna biosynthetic process GO:2001141 381 0.018
embryonic limb morphogenesis GO:0030326 4 0.018
cell migration GO:0016477 197 0.018
non canonical wnt signaling pathway GO:0035567 3 0.018
regulation of cellular amine metabolic process GO:0033238 8 0.018
protein oligomerization GO:0051259 191 0.018
response to hydrogen peroxide GO:0042542 89 0.018
nucleoside metabolic process GO:0009116 179 0.018
response to carbohydrate GO:0009743 183 0.018
cellular response to acid chemical GO:0071229 75 0.017
mesoderm development GO:0007498 2 0.017
positive regulation of apoptotic process GO:0043065 154 0.017
cellular response to peptide GO:1901653 133 0.017
regulation of phosphate metabolic process GO:0019220 349 0.017
negative regulation of cell death GO:0060548 229 0.017
cellular cation homeostasis GO:0030003 180 0.017
protein homooligomerization GO:0051260 91 0.017
female pregnancy GO:0007565 122 0.017
cellular homeostasis GO:0019725 252 0.017
transcription from rna polymerase ii promoter GO:0006366 252 0.017
regulation of transcription dna templated GO:0006355 374 0.017
cytosolic calcium ion homeostasis GO:0051480 140 0.017
organelle organization GO:0006996 266 0.017
ras protein signal transduction GO:0007265 29 0.017
regulation of cellular component movement GO:0051270 150 0.017
positive regulation of phosphorylation GO:0042327 177 0.017
regulation of protein modification process GO:0031399 194 0.017
cellular response to nitrogen compound GO:1901699 210 0.016
purine ribonucleoside triphosphate metabolic process GO:0009205 140 0.016
signal transduction by phosphorylation GO:0023014 144 0.016
positive regulation of cellular component movement GO:0051272 102 0.016
purine ribonucleoside metabolic process GO:0046128 168 0.016
hepaticobiliary system development GO:0061008 90 0.016
regulation of signal transduction GO:0009966 318 0.016
positive regulation of cellular component organization GO:0051130 200 0.016
epithelium development GO:0060429 96 0.016
muscle tissue development GO:0060537 58 0.016
calcium ion homeostasis GO:0055074 162 0.016
regulation of protein kinase activity GO:0045859 105 0.016
anatomical structure formation involved in morphogenesis GO:0048646 83 0.016
ribonucleoside triphosphate metabolic process GO:0009199 141 0.016
negative regulation of response to stimulus GO:0048585 155 0.016
cation transmembrane transport GO:0098655 263 0.016
formation of primary germ layer GO:0001704 1 0.016
regulation of hormone levels GO:0010817 187 0.015
reproductive structure development GO:0048608 128 0.015
intracellular transport GO:0046907 185 0.015
ion homeostasis GO:0050801 212 0.015
skeletal muscle tissue development GO:0007519 31 0.015
g protein coupled receptor signaling pathway GO:0007186 242 0.015
kidney development GO:0001822 67 0.015
transcription dna templated GO:0006351 377 0.015
gastrulation GO:0007369 2 0.015
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.015
purine ribonucleotide catabolic process GO:0009154 136 0.015
regulation of cell motility GO:2000145 131 0.015
purine ribonucleoside catabolic process GO:0046130 124 0.015
regulation of intracellular signal transduction GO:1902531 218 0.015
response to ethanol GO:0045471 162 0.015
aromatic compound catabolic process GO:0019439 168 0.015
negative regulation of natural killer cell mediated cytotoxicity GO:0045953 4 0.015
circulatory system process GO:0003013 183 0.015
macromolecule localization GO:0033036 252 0.015
response to cytokine GO:0034097 215 0.015
divalent inorganic cation transport GO:0072511 134 0.015
proteolysis GO:0006508 175 0.015
cellular response to steroid hormone stimulus GO:0071383 93 0.015
organophosphate catabolic process GO:0046434 148 0.015
regulation of epithelial cell proliferation GO:0050678 49 0.015
carbohydrate derivative catabolic process GO:1901136 147 0.015
cellular metal ion homeostasis GO:0006875 172 0.015
inorganic ion transmembrane transport GO:0098660 229 0.015
muscle organ development GO:0007517 50 0.015
purine nucleotide catabolic process GO:0006195 136 0.014
positive regulation of neuron differentiation GO:0045666 126 0.014
regulation of system process GO:0044057 208 0.014
positive regulation of cell communication GO:0010647 271 0.014
positive regulation of neurogenesis GO:0050769 165 0.014
cellular nitrogen compound catabolic process GO:0044270 163 0.014
rhythmic process GO:0048511 156 0.014
cytoplasmic transport GO:0016482 115 0.014
ossification GO:0001503 70 0.014
gonad development GO:0008406 104 0.014
cellular response to extracellular stimulus GO:0031668 73 0.014
regulation of neuron projection development GO:0010975 161 0.014
multi multicellular organism process GO:0044706 138 0.014
striated muscle tissue development GO:0014706 58 0.014
cellular divalent inorganic cation homeostasis GO:0072503 162 0.014
establishment of protein localization GO:0045184 141 0.014
purine nucleoside catabolic process GO:0006152 124 0.014
purine ribonucleoside triphosphate catabolic process GO:0009207 122 0.014
vesicle mediated transport GO:0016192 181 0.014
cytoskeleton organization GO:0007010 111 0.014
negative regulation of programmed cell death GO:0043069 183 0.014
regulation of kinase activity GO:0043549 117 0.014
glycosyl compound catabolic process GO:1901658 126 0.014
positive regulation of cell migration GO:0030335 96 0.014
establishment of planar polarity GO:0001736 1 0.013
single organism intracellular transport GO:1902582 166 0.013
small gtpase mediated signal transduction GO:0007264 36 0.013
response to hexose GO:0009746 144 0.013
positive regulation of cell death GO:0010942 184 0.013
neuron projection morphogenesis GO:0048812 122 0.013
positive regulation of signal transduction GO:0009967 175 0.013
cellular response to abiotic stimulus GO:0071214 85 0.013
skeletal muscle organ development GO:0060538 33 0.013
blood vessel morphogenesis GO:0048514 58 0.013
regulation of transferase activity GO:0051338 123 0.013
vasculature development GO:0001944 70 0.013
cellular response to oxidative stress GO:0034599 76 0.013
hindlimb morphogenesis GO:0035137 2 0.013
regulation of nucleic acid templated transcription GO:1903506 380 0.013
regulation of anatomical structure morphogenesis GO:0022603 141 0.013
connective tissue development GO:0061448 33 0.013
regulation of protein phosphorylation GO:0001932 183 0.013
cellular chemical homeostasis GO:0055082 247 0.013
muscle cell proliferation GO:0033002 84 0.013
response to reactive oxygen species GO:0000302 120 0.013
positive regulation of cellular biosynthetic process GO:0031328 295 0.013
response to bacterium GO:0009617 200 0.013
positive regulation of transport GO:0051050 245 0.013
axis specification GO:0009798 4 0.013
response to testosterone GO:0033574 55 0.013
positive regulation of protein phosphorylation GO:0001934 135 0.013
positive regulation of protein modification process GO:0031401 142 0.013
mapk cascade GO:0000165 140 0.013
lung development GO:0030324 43 0.013
defense response GO:0006952 194 0.012
regulation of establishment of planar polarity GO:0090175 2 0.012
forebrain development GO:0030900 98 0.012
nucleotide catabolic process GO:0009166 139 0.012
cellular component morphogenesis GO:0032989 155 0.012
negative regulation of multicellular organismal process GO:0051241 203 0.012
negative regulation of innate immune response GO:0045824 4 0.012
regulation of locomotion GO:0040012 148 0.012
rna metabolic process GO:0016070 406 0.012
positive regulation of cell projection organization GO:0031346 111 0.012
negative regulation of biosynthetic process GO:0009890 168 0.012
single organism carbohydrate metabolic process GO:0044723 118 0.012
positive regulation of cellular protein metabolic process GO:0032270 167 0.012
cellular response to fluid shear stress GO:0071498 4 0.012
neuronal action potential GO:0019228 35 0.012
cellular response to external stimulus GO:0071496 118 0.012
regulation of cell projection organization GO:0031344 175 0.012
muscle structure development GO:0061061 87 0.012
negative regulation of metabolic process GO:0009892 331 0.012
nucleobase containing compound catabolic process GO:0034655 152 0.012
lipid metabolic process GO:0006629 283 0.012
cell growth GO:0016049 104 0.012
ribonucleotide metabolic process GO:0009259 231 0.012
divalent inorganic cation homeostasis GO:0072507 165 0.012
nucleoside catabolic process GO:0009164 126 0.012
heart development GO:0007507 72 0.011
morphogenesis of embryonic epithelium GO:0016331 3 0.011
camera type eye morphogenesis GO:0048593 2 0.011
purine nucleoside triphosphate metabolic process GO:0009144 141 0.011
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.011
metal ion homeostasis GO:0055065 186 0.011
positive regulation of ion transport GO:0043270 94 0.011
heart morphogenesis GO:0003007 3 0.011
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.011
nucleoside triphosphate metabolic process GO:0009141 144 0.011
locomotion GO:0040011 237 0.011
negative regulation of cellular metabolic process GO:0031324 281 0.011
cellular ion homeostasis GO:0006873 184 0.011
response to camp GO:0051591 91 0.011
secretion by cell GO:0032940 248 0.011
response to biotic stimulus GO:0009607 226 0.011
guanosine containing compound metabolic process GO:1901068 74 0.011
positive regulation of transcription dna templated GO:0045893 197 0.011
negative regulation of canonical wnt signaling pathway GO:0090090 4 0.011
anterior posterior pattern specification GO:0009952 1 0.011
monovalent inorganic cation transport GO:0015672 172 0.011
positive regulation of nervous system development GO:0051962 178 0.011
small molecule catabolic process GO:0044282 59 0.011
inorganic cation transmembrane transport GO:0098662 202 0.011
calcium ion transport GO:0006816 131 0.011
response to organophosphorus GO:0046683 102 0.011
ribonucleotide catabolic process GO:0009261 136 0.010
regulation of map kinase activity GO:0043405 53 0.010
palate development GO:0060021 2 0.010
sequestering of calcium ion GO:0051208 8 0.010
mechanoreceptor differentiation GO:0042490 2 0.010
positive regulation of cytosolic calcium ion concentration GO:0007204 122 0.010
response to transforming growth factor beta GO:0071559 46 0.010
response to mechanical stimulus GO:0009612 134 0.010
growth GO:0040007 165 0.010
purine nucleoside triphosphate catabolic process GO:0009146 122 0.010
positive regulation of cell development GO:0010720 176 0.010
negative regulation of cell communication GO:0010648 158 0.010
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.010
response to activity GO:0014823 73 0.010
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.010
regulation of catabolic process GO:0009894 113 0.010
coronary vasculature morphogenesis GO:0060977 3 0.010

Smoc2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.031
musculoskeletal system disease DOID:17 0 0.031
nervous system disease DOID:863 0 0.023
myopathy DOID:423 0 0.016
muscular disease DOID:0080000 0 0.016
muscle tissue disease DOID:66 0 0.016
sensory system disease DOID:0050155 0 0.012
connective tissue disease DOID:65 0 0.010