Rattus norvegicus

0 known processes

Dync1h1

dynein cytoplasmic 1 heavy chain 1

(Aliases: Dnch1,Dnchc1)

Dync1h1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
macromolecular complex subunit organization GO:0043933 339 0.427
Mouse
organelle organization GO:0006996 266 0.313
Mouse
head development GO:0060322 247 0.232
single organism organelle organization GO:1902589 180 0.216
protein complex subunit organization GO:0071822 302 0.199
organophosphate metabolic process GO:0019637 370 0.191
mitotic spindle organization GO:0007052 2 0.141
protein complex biogenesis GO:0070271 263 0.129
microtubule cytoskeleton organization GO:0000226 25 0.125
cytoskeleton organization GO:0007010 111 0.124
transcription from rna polymerase ii promoter GO:0006366 252 0.122
cellular component biogenesis GO:0044085 368 0.113
Mouse
reproductive process GO:0022414 372 0.112
catabolic process GO:0009056 351 0.110
organic substance catabolic process GO:1901575 316 0.109
multicellular organismal water homeostasis GO:0050891 4 0.109
purine ribonucleoside catabolic process GO:0046130 124 0.108
intracellular transport GO:0046907 185 0.108
single organism intracellular transport GO:1902582 166 0.106
single organism cellular localization GO:1902580 102 0.106
macromolecule localization GO:0033036 252 0.099
cellular component movement GO:0006928 248 0.099
single organism catabolic process GO:0044712 283 0.094
single organism membrane organization GO:0044802 74 0.088
cellular lipid metabolic process GO:0044255 208 0.087
organelle localization GO:0051640 55 0.085
lipid metabolic process GO:0006629 283 0.084
cellular catabolic process GO:0044248 295 0.080
spindle organization GO:0007051 2 0.079
vesicle mediated transport GO:0016192 181 0.079
regulation of cell proliferation GO:0042127 359 0.074
purine ribonucleotide metabolic process GO:0009150 227 0.070
protein localization to chromosome centromeric region GO:0071459 1 0.070
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.069
positive regulation of nucleotide metabolic process GO:0045981 91 0.068
protein complex assembly GO:0006461 263 0.068
nucleoside triphosphate catabolic process GO:0009143 123 0.067
protein localization GO:0008104 191 0.065
neuron differentiation GO:0030182 368 0.064
response to nutrient levels GO:0031667 370 0.062
organophosphate catabolic process GO:0046434 148 0.061
regulation of nucleoside metabolic process GO:0009118 66 0.061
purine ribonucleoside triphosphate metabolic process GO:0009205 140 0.061
glycosyl compound catabolic process GO:1901658 126 0.060
regulation of rna metabolic process GO:0051252 391 0.060
ribonucleotide catabolic process GO:0009261 136 0.060
regulation of axonogenesis GO:0050770 37 0.059
central nervous system development GO:0007417 311 0.059
establishment of organelle localization GO:0051656 37 0.058
developmental growth GO:0048589 100 0.056
regulation of membrane potential GO:0042391 110 0.056
positive regulation of purine nucleotide metabolic process GO:1900544 91 0.055
response to extracellular stimulus GO:0009991 380 0.055
membrane organization GO:0061024 94 0.054
nucleoside phosphate metabolic process GO:0006753 283 0.054
nucleotide metabolic process GO:0009117 279 0.053
carboxylic acid metabolic process GO:0019752 289 0.052
nucleoside metabolic process GO:0009116 179 0.052
purine nucleoside metabolic process GO:0042278 169 0.052
apoptotic process GO:0006915 381 0.051
brain development GO:0007420 247 0.051
purine ribonucleoside triphosphate catabolic process GO:0009207 122 0.051
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.050
anatomical structure morphogenesis GO:0009653 298 0.050
regulation of rna biosynthetic process GO:2001141 381 0.050
glycosyl compound metabolic process GO:1901657 182 0.050
protein oligomerization GO:0051259 191 0.049
macromolecular complex assembly GO:0065003 273 0.049
Mouse
glycerolipid metabolic process GO:0046486 67 0.049
cellular response to oxidative stress GO:0034599 76 0.048
regulation of purine nucleotide catabolic process GO:0033121 65 0.047
nucleoside phosphate catabolic process GO:1901292 140 0.047
small gtpase mediated signal transduction GO:0007264 36 0.046
response to nutrient GO:0007584 248 0.046
axon cargo transport GO:0008088 1 0.045
cytoplasmic transport GO:0016482 115 0.045
organonitrogen compound catabolic process GO:1901565 179 0.043
response to metal ion GO:0010038 253 0.043
organic cyclic compound catabolic process GO:1901361 175 0.043
rna biosynthetic process GO:0032774 380 0.043
rna metabolic process GO:0016070 406 0.041
regulation of nucleotide catabolic process GO:0030811 65 0.041
g protein coupled receptor signaling pathway GO:0007186 242 0.041
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.040
purine nucleoside catabolic process GO:0006152 124 0.039
positive regulation of nucleoside metabolic process GO:0045979 55 0.039
cellular response to stress GO:0033554 269 0.038
lipid biosynthetic process GO:0008610 128 0.037
multicellular organismal signaling GO:0035637 44 0.037
cellular macromolecule localization GO:0070727 122 0.036
regulation of neurogenesis GO:0050767 247 0.036
cellular divalent inorganic cation homeostasis GO:0072503 162 0.036
hepaticobiliary system development GO:0061008 90 0.036
nucleobase containing small molecule metabolic process GO:0055086 316 0.036
regulation of gtpase activity GO:0043087 57 0.035
epithelium development GO:0060429 96 0.035
cell fate determination GO:0001709 2 0.034
positive regulation of catabolic process GO:0009896 78 0.034
ras protein signal transduction GO:0007265 29 0.034
ribose phosphate metabolic process GO:0019693 235 0.034
protein ubiquitination GO:0016567 28 0.034
transcription dna templated GO:0006351 377 0.034
regulation of body fluid levels GO:0050878 90 0.033
guanosine containing compound metabolic process GO:1901068 74 0.033
purine containing compound catabolic process GO:0072523 138 0.033
protein heterooligomerization GO:0051291 89 0.032
positive regulation of programmed cell death GO:0043068 157 0.032
cellular protein localization GO:0034613 122 0.032
defense response GO:0006952 194 0.031
intracellular signal transduction GO:0035556 314 0.031
liver development GO:0001889 90 0.030
aromatic compound catabolic process GO:0019439 168 0.030
regulation of neural precursor cell proliferation GO:2000177 16 0.030
purine nucleoside triphosphate catabolic process GO:0009146 122 0.030
regulation of ras gtpase activity GO:0032318 32 0.029
positive regulation of nucleic acid templated transcription GO:1903508 197 0.029
programmed cell death GO:0012501 392 0.029
cell cell signaling GO:0007267 335 0.029
regulation of cellular catabolic process GO:0031329 101 0.029
reproduction GO:0000003 245 0.028
protein modification by small protein conjugation or removal GO:0070647 35 0.028
ribonucleoside triphosphate metabolic process GO:0009199 141 0.028
inorganic ion transmembrane transport GO:0098660 229 0.028
carbohydrate derivative metabolic process GO:1901135 346 0.028
positive regulation of transport GO:0051050 245 0.028
cellular nitrogen compound catabolic process GO:0044270 163 0.028
tissue development GO:0009888 252 0.028
nucleobase containing compound catabolic process GO:0034655 152 0.027
nucleotide catabolic process GO:0009166 139 0.027
intracellular protein transport GO:0006886 79 0.027
purine ribonucleoside metabolic process GO:0046128 168 0.027
immune system process GO:0002376 204 0.026
positive regulation of nervous system development GO:0051962 178 0.026
organic hydroxy compound metabolic process GO:1901615 115 0.026
cellular response to growth factor stimulus GO:0071363 162 0.026
regulation of molecular function GO:0065009 398 0.025
norepinephrine transport GO:0015874 18 0.025
phosphatidylinositol dephosphorylation GO:0046856 4 0.025
cellular macromolecular complex assembly GO:0034622 58 0.025
Mouse
ribonucleoside catabolic process GO:0042454 126 0.025
sequestering of calcium ion GO:0051208 8 0.025
phospholipid metabolic process GO:0006644 61 0.025
cellular response to endogenous stimulus GO:0071495 377 0.025
synaptic transmission GO:0007268 235 0.025
positive regulation of cellular catabolic process GO:0031331 71 0.024
adult locomotory behavior GO:0008344 4 0.024
glycerophospholipid metabolic process GO:0006650 47 0.024
regulation of nucleic acid templated transcription GO:1903506 380 0.024
secretion by cell GO:0032940 248 0.024
synaptic growth at neuromuscular junction GO:0051124 1 0.024
positive regulation of biosynthetic process GO:0009891 319 0.024
multi organism reproductive process GO:0044703 262 0.023
purine nucleotide metabolic process GO:0006163 229 0.023
sequestering of metal ion GO:0051238 9 0.023
carbohydrate derivative catabolic process GO:1901136 147 0.023
neuronal ion channel clustering GO:0045161 3 0.023
nucleocytoplasmic transport GO:0006913 48 0.023
regulation of cell differentiation GO:0045595 320 0.022
purine nucleoside triphosphate metabolic process GO:0009144 141 0.022
positive regulation of cell development GO:0010720 176 0.022
regulation of catabolic process GO:0009894 113 0.022
positive regulation of cellular biosynthetic process GO:0031328 295 0.022
growth GO:0040007 165 0.022
nitrogen compound transport GO:0071705 229 0.022
regulation of apoptotic process GO:0042981 335 0.022
cell morphogenesis involved in neuron differentiation GO:0048667 106 0.022
cellular metal ion homeostasis GO:0006875 172 0.021
neural precursor cell proliferation GO:0061351 23 0.021
positive regulation of cell differentiation GO:0045597 217 0.021
multicellular organism reproduction GO:0032504 233 0.021
response to estradiol GO:0032355 164 0.021
cation transport GO:0006812 382 0.021
ribonucleotide metabolic process GO:0009259 231 0.021
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.021
action potential GO:0001508 54 0.021
forebrain development GO:0030900 98 0.021
ribonucleoside triphosphate catabolic process GO:0009203 122 0.020
sexual reproduction GO:0019953 148 0.020
positive regulation of transcription dna templated GO:0045893 197 0.020
response to lipopolysaccharide GO:0032496 191 0.020
purine containing compound metabolic process GO:0072521 253 0.020
multicellular organismal reproductive process GO:0048609 233 0.020
positive regulation of multicellular organismal process GO:0051240 387 0.020
protein tetramerization GO:0051262 38 0.020
regulation of multicellular organismal development GO:2000026 376 0.019
purine ribonucleoside monophosphate catabolic process GO:0009169 55 0.019
neuron development GO:0048666 286 0.019
signal release GO:0023061 145 0.019
protein ubiquitination involved in ubiquitin dependent protein catabolic process GO:0042787 3 0.019
chemical homeostasis GO:0048878 292 0.019
nucleoside triphosphate metabolic process GO:0009141 144 0.019
transmembrane transport GO:0055085 412 0.019
regulation of hydrolase activity GO:0051336 143 0.019
positive regulation of gene expression GO:0010628 244 0.019
regulation of proteasomal protein catabolic process GO:0061136 4 0.019
positive regulation of purine nucleotide catabolic process GO:0033123 53 0.019
positive regulation of cellular component organization GO:0051130 200 0.019
gtp metabolic process GO:0046039 72 0.019
response to growth factor GO:0070848 189 0.018
mitotic cell cycle process GO:1903047 35 0.018
regulation of cell growth GO:0001558 85 0.018
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.018
endomembrane system organization GO:0010256 48 0.018
cation homeostasis GO:0055080 195 0.018
positive regulation of nucleotide catabolic process GO:0030813 53 0.018
cardiovascular system development GO:0072358 134 0.018
regeneration GO:0031099 163 0.018
regulation of response to stress GO:0080134 126 0.018
synaptic transmission gabaergic GO:0051932 22 0.018
epithelial cell differentiation GO:0030855 71 0.018
purine ribonucleotide catabolic process GO:0009154 136 0.017
lipid modification GO:0030258 52 0.017
alcohol metabolic process GO:0006066 77 0.017
protein phosphorylation GO:0006468 345 0.017
negative regulation of metabolic process GO:0009892 331 0.017
regulation of cell development GO:0060284 263 0.017
heterocycle catabolic process GO:0046700 167 0.017
neuromuscular process GO:0050905 2 0.017
regulation of cellular component organization GO:0051128 368 0.017
stem cell division GO:0017145 4 0.017
eye morphogenesis GO:0048592 4 0.017
positive regulation of gtpase activity GO:0043547 47 0.017
cellular amine metabolic process GO:0044106 38 0.017
purine nucleotide catabolic process GO:0006195 136 0.017
negative regulation of organ growth GO:0046621 3 0.017
cell projection organization GO:0030030 302 0.017
gland development GO:0048732 155 0.017
establishment of protein localization GO:0045184 141 0.016
limb morphogenesis GO:0035108 4 0.016
retrograde axon cargo transport GO:0008090 1 0.016
proteolysis GO:0006508 175 0.016
cellular homeostasis GO:0019725 252 0.016
gtp catabolic process GO:0006184 71 0.016
nucleic acid transport GO:0050657 3 0.016
response to oxidative stress GO:0006979 186 0.016
negative regulation of neurogenesis GO:0050768 78 0.016
regulation of transcription dna templated GO:0006355 374 0.016
nucleic acid templated transcription GO:0097659 379 0.016
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 85 0.016
cellular response to nitrogen compound GO:1901699 210 0.016
positive regulation of calcium ion transport GO:0051928 36 0.015
positive regulation of rna metabolic process GO:0051254 203 0.015
ion homeostasis GO:0050801 212 0.015
regulation of hormone levels GO:0010817 187 0.015
vasculogenesis GO:0001570 3 0.015
insulin like growth factor receptor signaling pathway GO:0048009 3 0.015
neuron projection development GO:0031175 273 0.015
embryonic limb morphogenesis GO:0030326 4 0.015
regulation of catalytic activity GO:0050790 304 0.015
response to cadmium ion GO:0046686 35 0.015
protein transport GO:0015031 132 0.015
metal ion homeostasis GO:0055065 186 0.015
negative regulation of cellular response to insulin stimulus GO:1900077 11 0.015
chromatin assembly or disassembly GO:0006333 1 0.015
protein prenylation GO:0018342 4 0.015
inorganic cation transmembrane transport GO:0098662 202 0.015
regulation of neuron differentiation GO:0045664 208 0.015
cation transmembrane transport GO:0098655 263 0.015
cellular component morphogenesis GO:0032989 155 0.014
cellular component assembly GO:0022607 360 0.014
Mouse
cell cycle process GO:0022402 57 0.014
positive regulation of cell death GO:0010942 184 0.014
ribonucleoside metabolic process GO:0009119 174 0.014
carbohydrate metabolic process GO:0005975 130 0.014
axonogenesis GO:0007409 71 0.014
regulation of programmed cell death GO:0043067 341 0.014
regulation of gtp catabolic process GO:0033124 58 0.014
cell morphogenesis involved in differentiation GO:0000904 119 0.014
artery development GO:0060840 3 0.014
acute inflammatory response GO:0002526 58 0.014
divalent inorganic cation homeostasis GO:0072507 165 0.014
negative regulation of signaling GO:0023057 157 0.014
negative regulation of cellular component organization GO:0051129 83 0.013
regulation of small gtpase mediated signal transduction GO:0051056 48 0.013
regulation of phosphate metabolic process GO:0019220 349 0.013
anterior posterior pattern specification GO:0009952 1 0.013
regulation of nucleotide metabolic process GO:0006140 117 0.013
microtubule anchoring GO:0034453 1 0.013
regulation of response to external stimulus GO:0032101 106 0.013
positive regulation of catalytic activity GO:0043085 184 0.013
regulation of neuron projection development GO:0010975 161 0.013
cell projection morphogenesis GO:0048858 123 0.013
regulation of system process GO:0044057 208 0.013
protein geranylgeranylation GO:0018344 4 0.013
asymmetric stem cell division GO:0098722 2 0.013
actin cytoskeleton organization GO:0030036 73 0.013
positive regulation of neuron differentiation GO:0045666 126 0.013
negative regulation of developmental process GO:0051093 125 0.013
positive regulation of gtp catabolic process GO:0033126 48 0.013
aging GO:0007568 241 0.013
spermatogenesis GO:0007283 99 0.013
regulation of growth GO:0040008 105 0.013
cellular protein complex assembly GO:0043623 44 0.013
regulation of locomotion GO:0040012 148 0.013
regulation of cellular amino acid metabolic process GO:0006521 2 0.012
response to toxic substance GO:0009636 133 0.012
multicellular organism growth GO:0035264 1 0.012
rna localization GO:0006403 4 0.012
endosomal transport GO:0016197 14 0.012
monoamine transport GO:0015844 43 0.012
negative regulation of innate immune response GO:0045824 4 0.012
single organism reproductive process GO:0044702 297 0.012
endosome to lysosome transport GO:0008333 6 0.012
cellular response to oxygen containing compound GO:1901701 386 0.012
response to inorganic substance GO:0010035 377 0.012
response to insulin GO:0032868 133 0.012
protein homooligomerization GO:0051260 91 0.012
receptor mediated endocytosis GO:0006898 42 0.012
choline transport GO:0015871 4 0.012
hormone secretion GO:0046879 115 0.012
cell cycle GO:0007049 101 0.012
inorganic anion transport GO:0015698 41 0.012
endocytosis GO:0006897 84 0.011
cellular ion homeostasis GO:0006873 184 0.011
chromosome organization GO:0051276 36 0.011
protein modification by small protein conjugation GO:0032446 31 0.011
regulation of microtubule based process GO:0032886 14 0.011
localization of cell GO:0051674 202 0.011
guanosine containing compound catabolic process GO:1901069 71 0.011
positive regulation of phosphorus metabolic process GO:0010562 262 0.011
neurotransmitter gated ion channel clustering GO:0072578 3 0.011
hepatocyte growth factor receptor signaling pathway GO:0048012 1 0.011
organophosphate biosynthetic process GO:0090407 143 0.011
positive regulation of homeostatic process GO:0032846 49 0.011
angioblast cell migration GO:0035476 1 0.011
positive regulation of ion transport GO:0043270 94 0.011
neuronal stem cell division GO:0036445 1 0.011
regulation of cell morphogenesis involved in differentiation GO:0010769 72 0.011
gamete generation GO:0007276 124 0.011
negative regulation of cell development GO:0010721 82 0.011
transmission of nerve impulse GO:0019226 42 0.011
gliogenesis GO:0042063 93 0.011
small molecule catabolic process GO:0044282 59 0.011
amine metabolic process GO:0009308 38 0.011
chromosome segregation GO:0007059 2 0.011
ion transmembrane transport GO:0034220 365 0.011
negative regulation of multicellular organismal process GO:0051241 203 0.011
nuclear import GO:0051170 35 0.011
cellular response to organonitrogen compound GO:0071417 197 0.011
regulation of purine nucleotide metabolic process GO:1900542 115 0.011
cellular chemical homeostasis GO:0055082 247 0.011
cellular component maintenance GO:0043954 4 0.011
negative regulation of nervous system development GO:0051961 79 0.011
regulation of cellular component movement GO:0051270 150 0.011
necroptotic process GO:0070266 2 0.010
single organism biosynthetic process GO:0044711 342 0.010
single organism carbohydrate catabolic process GO:0044724 40 0.010
negative regulation of vascular permeability GO:0043116 3 0.010
monocarboxylic acid metabolic process GO:0032787 152 0.010
male gamete generation GO:0048232 99 0.010
oxoacid metabolic process GO:0043436 290 0.010
metal ion transport GO:0030001 289 0.010
negative regulation of cell communication GO:0010648 158 0.010
calcium ion transport into cytosol GO:0060402 38 0.010
positive regulation of cell projection organization GO:0031346 111 0.010
rho protein signal transduction GO:0007266 11 0.010
response to decreased oxygen levels GO:0036293 237 0.010

Dync1h1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
epilepsy syndrome DOID:1826 0 0.312
central nervous system disease DOID:331 0 0.312
brain disease DOID:936 0 0.312
disease of anatomical entity DOID:7 0 0.312
nervous system disease DOID:863 0 0.312
electroclinical syndrome DOID:0050701 0 0.063
idiopathic generalized epilepsy DOID:1827 0 0.057
neonatal period electroclinical syndrome DOID:0050702 0 0.012
ohtahara syndrome DOID:0050709 0 0.012