Rattus norvegicus

132 known processes

Casq2

calsequestrin 2 (cardiac muscle)

Casq2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cardiac muscle contraction GO:0060048 27 0.918
striated muscle contraction GO:0006941 44 0.824
muscle contraction GO:0006936 88 0.792
actin filament based movement GO:0030048 16 0.786
heart process GO:0003015 57 0.730
cardiac muscle tissue morphogenesis GO:0055008 1 0.716
actin mediated cell contraction GO:0070252 12 0.711
regulation of system process GO:0044057 208 0.675
cardiac ventricle development GO:0003231 1 0.655
regulation of cardiac muscle contraction by calcium ion signaling GO:0010882 3 0.647
blood circulation GO:0008015 183 0.564
heart contraction GO:0060047 57 0.563
regulation of muscle system process GO:0090257 79 0.529
heart morphogenesis GO:0003007 3 0.516
regulation of muscle contraction GO:0006937 53 0.511
cardiac chamber development GO:0003205 1 0.469
muscle system process GO:0003012 115 0.433
regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum GO:0010880 4 0.424
cardiac myofibril assembly GO:0055003 1 0.406
response to nutrient GO:0007584 248 0.305
response to mechanical stimulus GO:0009612 134 0.304
regulation of actin filament based movement GO:1903115 12 0.302
circulatory system process GO:0003013 183 0.288
single organism catabolic process GO:0044712 283 0.288
actin filament based process GO:0030029 86 0.275
heart development GO:0007507 72 0.271
endoplasmic reticulum to cytosol transport GO:1903513 4 0.268
glycosyl compound metabolic process GO:1901657 182 0.248
catabolic process GO:0009056 351 0.245
aromatic compound catabolic process GO:0019439 168 0.242
purine nucleoside monophosphate catabolic process GO:0009128 55 0.237
cardiovascular system development GO:0072358 134 0.235
regulation of striated muscle contraction GO:0006942 21 0.235
actin myosin filament sliding GO:0033275 2 0.232
striated muscle tissue development GO:0014706 58 0.230
Rat
carbohydrate derivative metabolic process GO:1901135 346 0.221
ribonucleoside triphosphate catabolic process GO:0009203 122 0.221
regulation of blood circulation GO:1903522 110 0.221
purine ribonucleoside monophosphate catabolic process GO:0009169 55 0.219
organophosphate metabolic process GO:0019637 370 0.216
muscle tissue development GO:0060537 58 0.211
Rat
cellular chemical homeostasis GO:0055082 247 0.206
homeostatic process GO:0042592 331 0.203
nucleoside triphosphate catabolic process GO:0009143 123 0.203
ribonucleoside catabolic process GO:0042454 126 0.199
organonitrogen compound catabolic process GO:1901565 179 0.199
response to decreased oxygen levels GO:0036293 237 0.199
calcium ion homeostasis GO:0055074 162 0.188
sarcoplasmic reticulum calcium ion transport GO:0070296 8 0.186
regulation of heart contraction GO:0008016 48 0.184
atp catabolic process GO:0006200 54 0.181
transmembrane transport GO:0055085 412 0.176
cation homeostasis GO:0055080 195 0.172
protein complex biogenesis GO:0070271 263 0.171
Human
inorganic ion transmembrane transport GO:0098660 229 0.170
metal ion homeostasis GO:0055065 186 0.169
purine nucleotide metabolic process GO:0006163 229 0.159
cellular catabolic process GO:0044248 295 0.152
response to muscle stretch GO:0035994 2 0.152
ventricular cardiac muscle cell action potential GO:0086005 2 0.148
regulation of hormone levels GO:0010817 187 0.148
response to heat GO:0009408 60 0.146
response to inorganic substance GO:0010035 377 0.143
nucleotide metabolic process GO:0009117 279 0.143
ribonucleotide catabolic process GO:0009261 136 0.137
cardiac muscle cell action potential GO:0086001 5 0.135
atp metabolic process GO:0046034 72 0.133
calcium ion transport from endoplasmic reticulum to cytosol GO:1903514 4 0.132
cytoskeleton organization GO:0007010 111 0.130
ribonucleotide metabolic process GO:0009259 231 0.130
cardiac muscle cell development GO:0055013 16 0.128
organic substance catabolic process GO:1901575 316 0.121
release of sequestered calcium ion into cytosol by sarcoplasmic reticulum GO:0014808 4 0.120
purine ribonucleotide catabolic process GO:0009154 136 0.119
cellular metal ion homeostasis GO:0006875 172 0.119
cellular homeostasis GO:0019725 252 0.119
nucleoside monophosphate catabolic process GO:0009125 56 0.118
ribonucleoside monophosphate catabolic process GO:0009158 55 0.117
cellular component assembly GO:0022607 360 0.117
Human
response to metal ion GO:0010038 253 0.115
nucleoside phosphate catabolic process GO:1901292 140 0.114
regulation of cardiac muscle contraction GO:0055117 17 0.113
inorganic cation transmembrane transport GO:0098662 202 0.112
muscle tissue morphogenesis GO:0060415 1 0.110
cellular component movement GO:0006928 248 0.110
organophosphate catabolic process GO:0046434 148 0.109
positive regulation of cytosolic calcium ion concentration GO:0007204 122 0.107
organic cyclic compound catabolic process GO:1901361 175 0.107
nucleoside catabolic process GO:0009164 126 0.106
purine nucleotide catabolic process GO:0006195 136 0.101
ribose phosphate metabolic process GO:0019693 235 0.101
cardiac conduction GO:0061337 2 0.100
anatomical structure morphogenesis GO:0009653 298 0.099
nucleoside triphosphate metabolic process GO:0009141 144 0.099
regulation of apoptotic process GO:0042981 335 0.097
purine ribonucleoside triphosphate metabolic process GO:0009205 140 0.096
multicellular organismal movement GO:0050879 17 0.095
cardiac muscle tissue development GO:0048738 26 0.093
apoptotic process GO:0006915 381 0.093
cellular cation homeostasis GO:0030003 180 0.090
purine ribonucleotide metabolic process GO:0009150 227 0.090
regulation of hormone secretion GO:0046883 106 0.090
purine containing compound catabolic process GO:0072523 138 0.088
cellular nitrogen compound catabolic process GO:0044270 163 0.087
regulation of ion transport GO:0043269 245 0.087
nucleobase containing small molecule metabolic process GO:0055086 316 0.087
purine nucleoside triphosphate catabolic process GO:0009146 122 0.085
tissue development GO:0009888 252 0.085
Rat
response to vitamin GO:0033273 131 0.084
response to corticosteroid GO:0031960 235 0.084
positive regulation of response to stimulus GO:0048584 285 0.082
response to nutrient levels GO:0031667 370 0.081
response to monosaccharide GO:0034284 159 0.081
response to growth factor GO:0070848 189 0.081
enzyme linked receptor protein signaling pathway GO:0007167 116 0.079
nucleotide catabolic process GO:0009166 139 0.078
heterocycle catabolic process GO:0046700 167 0.077
purine nucleoside monophosphate metabolic process GO:0009126 84 0.076
purine ribonucleoside triphosphate catabolic process GO:0009207 122 0.075
cellular divalent inorganic cation homeostasis GO:0072503 162 0.075
organelle organization GO:0006996 266 0.075
response to peptide GO:1901652 292 0.074
positive regulation of signal transduction GO:0009967 175 0.074
regulation of heart rate GO:0002027 16 0.074
Human
nucleoside phosphate metabolic process GO:0006753 283 0.073
tissue morphogenesis GO:0048729 22 0.072
purine nucleoside catabolic process GO:0006152 124 0.071
reproduction GO:0000003 245 0.070
response to extracellular stimulus GO:0009991 380 0.070
nitrogen compound transport GO:0071705 229 0.069
purine ribonucleoside monophosphate metabolic process GO:0009167 84 0.068
positive regulation of cell communication GO:0010647 271 0.067
ribonucleoside metabolic process GO:0009119 174 0.067
cellular response to endogenous stimulus GO:0071495 377 0.067
Human
nucleobase containing compound catabolic process GO:0034655 152 0.065
regulation of actin filament based process GO:0032970 42 0.064
single organism reproductive process GO:0044702 297 0.063
purine ribonucleoside catabolic process GO:0046130 124 0.063
muscle cell differentiation GO:0042692 52 0.062
cellular ion homeostasis GO:0006873 184 0.060
cellular component biogenesis GO:0044085 368 0.060
Human
purine containing compound metabolic process GO:0072521 253 0.058
carbohydrate derivative catabolic process GO:1901136 147 0.057
cellular calcium ion homeostasis GO:0006874 160 0.057
protein phosphorylation GO:0006468 345 0.057
single organism organelle organization GO:1902589 180 0.056
positive regulation of signaling GO:0023056 270 0.056
positive regulation of multicellular organismal process GO:0051240 387 0.056
response to oxygen levels GO:0070482 265 0.055
regeneration GO:0031099 163 0.055
circulatory system development GO:0072359 134 0.055
twitch skeletal muscle contraction GO:0014721 3 0.055
protein complex subunit organization GO:0071822 302 0.055
Human
muscle structure development GO:0061061 87 0.055
Rat
regulation of kinase activity GO:0043549 117 0.054
response to hypoxia GO:0001666 231 0.054
cardiac muscle cell contraction GO:0086003 10 0.054
skeletal muscle tissue development GO:0007519 31 0.053
Rat
multicellular organism reproduction GO:0032504 233 0.053
striated muscle cell development GO:0055002 26 0.053
cellular response to external stimulus GO:0071496 118 0.052
aging GO:0007568 241 0.052
purine ribonucleoside metabolic process GO:0046128 168 0.051
musculoskeletal movement GO:0050881 17 0.051
positive regulation of transport GO:0051050 245 0.051
response to hexose GO:0009746 144 0.051
regulation of metal ion transport GO:0010959 118 0.051
secretion by cell GO:0032940 248 0.050
macromolecular complex assembly GO:0065003 273 0.050
Human
regulation of cellular localization GO:0060341 263 0.050
purine nucleoside triphosphate metabolic process GO:0009144 141 0.050
regulation of ion transmembrane transport GO:0034765 121 0.050
hormone transport GO:0009914 121 0.049
cardiac muscle cell action potential involved in contraction GO:0086002 2 0.048
response to glucose GO:0009749 136 0.048
regulation of cellular catabolic process GO:0031329 101 0.048
response to vitamin d GO:0033280 34 0.048
regulation of cardiac muscle cell contraction GO:0086004 11 0.048
regulation of purine nucleotide metabolic process GO:1900542 115 0.047
cellular response to abiotic stimulus GO:0071214 85 0.047
regulation of phagocytosis engulfment GO:0060099 4 0.046
chemical homeostasis GO:0048878 292 0.046
response to temperature stimulus GO:0009266 94 0.045
hormone secretion GO:0046879 115 0.045
regulation of atpase activity GO:0043462 7 0.045
positive regulation of phosphate metabolic process GO:0045937 262 0.044
regulation of phosphate metabolic process GO:0019220 349 0.043
muscle organ development GO:0007517 50 0.042
Rat
muscle organ morphogenesis GO:0048644 1 0.042
intracellular signal transduction GO:0035556 314 0.042
carbohydrate metabolic process GO:0005975 130 0.041
locomotion GO:0040011 237 0.041
negative regulation of secretion GO:0051048 82 0.041
peptide hormone secretion GO:0030072 84 0.040
peptide metabolic process GO:0006518 32 0.040
regulation of transferase activity GO:0051338 123 0.040
divalent inorganic cation homeostasis GO:0072507 165 0.039
response to carbohydrate GO:0009743 183 0.039
cellular macromolecule localization GO:0070727 122 0.039
cell communication involved in cardiac conduction GO:0086065 2 0.038
cellular response to nitrogen compound GO:1901699 210 0.038
Human
response to estrogen GO:0043627 232 0.038
oxoacid metabolic process GO:0043436 290 0.037
developmental process involved in reproduction GO:0003006 159 0.037
vascular process in circulatory system GO:0003018 96 0.036
multicellular organismal reproductive process GO:0048609 233 0.036
cardiocyte differentiation GO:0035051 22 0.036
cellular potassium ion transport GO:0071804 72 0.036
regulation of secretion by cell GO:1903530 208 0.035
positive regulation of cellular component organization GO:0051130 200 0.035
reproductive structure development GO:0048608 128 0.034
ribonucleoside monophosphate metabolic process GO:0009161 88 0.034
regulation of sodium ion transmembrane transporter activity GO:2000649 4 0.034
signal release GO:0023061 145 0.034
purine nucleoside metabolic process GO:0042278 169 0.034
positive regulation of apoptotic process GO:0043065 154 0.034
insulin secretion GO:0030073 69 0.033
response to glucocorticoid GO:0051384 223 0.033
positive regulation of cell differentiation GO:0045597 217 0.033
vasodilation GO:0042311 44 0.031
actin cytoskeleton organization GO:0030036 73 0.031
positive regulation of gene expression GO:0010628 244 0.031
transcription dna templated GO:0006351 377 0.030
cation transport GO:0006812 382 0.030
response to peptide hormone GO:0043434 278 0.030
single organism carbohydrate metabolic process GO:0044723 118 0.030
lipid transport GO:0006869 61 0.030
cellular modified amino acid metabolic process GO:0006575 61 0.029
ion homeostasis GO:0050801 212 0.029
positive regulation of developmental process GO:0051094 283 0.029
cellular protein complex assembly GO:0043623 44 0.029
Human
cytosolic calcium ion homeostasis GO:0051480 140 0.029
regulation of peptide hormone secretion GO:0090276 80 0.028
macromolecule localization GO:0033036 252 0.028
regulation of tube size GO:0035150 89 0.028
cardiac cell development GO:0055006 16 0.028
skeletal muscle contraction GO:0003009 17 0.028
alcohol metabolic process GO:0006066 77 0.027
ion transmembrane transport GO:0034220 365 0.027
metal ion transport GO:0030001 289 0.027
cellular component morphogenesis GO:0032989 155 0.026
response to purine containing compound GO:0014074 126 0.026
Human
programmed cell death GO:0012501 392 0.026
muscle filament sliding GO:0030049 2 0.026
endothelium development GO:0003158 12 0.026
regulation of transmembrane transport GO:0034762 122 0.026
regulation of cellular component organization GO:0051128 368 0.026
regulation of cell differentiation GO:0045595 320 0.026
regulation of secretion GO:0051046 224 0.026
lipid metabolic process GO:0006629 283 0.026
positive regulation of cell death GO:0010942 184 0.026
cellular response to oxygen containing compound GO:1901701 386 0.025
cellular response to stress GO:0033554 269 0.025
regulation of programmed cell death GO:0043067 341 0.025
regulation of release of sequestered calcium ion into cytosol GO:0051279 18 0.025
regulation of cellular component movement GO:0051270 150 0.025
regulation of multicellular organismal development GO:2000026 376 0.024
positive regulation of protein serine threonine kinase activity GO:0071902 52 0.024
regulation of endocytosis GO:0030100 42 0.024
organonitrogen compound biosynthetic process GO:1901566 167 0.024
cellular response to alcohol GO:0097306 87 0.024
secretion GO:0046903 307 0.024
fat cell proliferation GO:0070341 2 0.024
positive regulation of protein metabolic process GO:0051247 178 0.023
muscle cell development GO:0055001 26 0.023
bmp signaling pathway GO:0030509 4 0.023
growth GO:0040007 165 0.023
regulation of cytoskeleton organization GO:0051493 49 0.023
ribonucleoside triphosphate metabolic process GO:0009199 141 0.023
negative regulation of apoptotic process GO:0043066 181 0.022
organophosphate biosynthetic process GO:0090407 143 0.022
response to ketone GO:1901654 182 0.022
cellular protein localization GO:0034613 122 0.022
response to acid chemical GO:0001101 222 0.022
cellular amine metabolic process GO:0044106 38 0.022
regulation of insulin secretion GO:0050796 65 0.022
cellular response to growth factor stimulus GO:0071363 162 0.022
glucose homeostasis GO:0042593 75 0.022
positive regulation of fat cell proliferation GO:0070346 1 0.022
negative regulation of signaling GO:0023057 157 0.021
cellular carbohydrate metabolic process GO:0044262 72 0.021
cellular response to peptide GO:1901653 133 0.021
cell projection organization GO:0030030 302 0.021
small gtpase mediated signal transduction GO:0007264 36 0.021
positive regulation of transmembrane transport GO:0034764 25 0.021
development of primary female sexual characteristics GO:0046545 56 0.021
organ morphogenesis GO:0009887 75 0.021
regulation of neurological system process GO:0031644 43 0.021
neuron apoptotic process GO:0051402 88 0.021
g protein coupled receptor signaling pathway GO:0007186 242 0.021
carbohydrate homeostasis GO:0033500 75 0.021
multicellular organismal signaling GO:0035637 44 0.021
membrane depolarization during action potential GO:0086010 1 0.020
chemotaxis GO:0006935 66 0.020
positive regulation of protein phosphorylation GO:0001934 135 0.020
negative regulation of transport GO:0051051 136 0.020
regulation of phosphorylation GO:0042325 248 0.020
response to calcium ion GO:0051592 59 0.020
regulation of membrane repolarization GO:0060306 1 0.020
organelle assembly GO:0070925 22 0.020
negative regulation of cellular metabolic process GO:0031324 281 0.020
regulation of catabolic process GO:0009894 113 0.020
positive regulation of brown fat cell proliferation GO:0070349 1 0.020
regulation of cell proliferation GO:0042127 359 0.020
rna biosynthetic process GO:0032774 380 0.019
carbohydrate derivative biosynthetic process GO:1901137 124 0.019
regulation of nervous system development GO:0051960 264 0.019
gamete generation GO:0007276 124 0.019
regulation of nucleic acid templated transcription GO:1903506 380 0.019
cellular response to peptide hormone stimulus GO:0071375 120 0.019
regulation of purine nucleotide catabolic process GO:0033121 65 0.019
skeletal muscle cell differentiation GO:0035914 2 0.019
regulation of molecular function GO:0065009 398 0.019
regulation of signal transduction GO:0009966 318 0.019
glycosyl compound catabolic process GO:1901658 126 0.019
cell projection morphogenesis GO:0048858 123 0.019
negative regulation of cell communication GO:0010648 158 0.019
positive regulation of peptide hormone secretion GO:0090277 50 0.019
cellular response to organonitrogen compound GO:0071417 197 0.019
Human
single organism biosynthetic process GO:0044711 342 0.019
cellular response to organic cyclic compound GO:0071407 202 0.019
Human
regulation of transporter activity GO:0032409 50 0.019
organ growth GO:0035265 24 0.018
tube development GO:0035295 89 0.018
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.018
response to estradiol GO:0032355 164 0.018
epithelium development GO:0060429 96 0.018
response to activity GO:0014823 73 0.018
defense response GO:0006952 194 0.018
regulation of blood vessel size GO:0050880 89 0.018
regulation of smooth muscle cell proliferation GO:0048660 75 0.018
positive regulation of ion transmembrane transport GO:0034767 24 0.018
cellular macromolecular complex assembly GO:0034622 58 0.018
Human
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.018
nucleic acid templated transcription GO:0097659 379 0.018
reproductive process GO:0022414 372 0.018
response to wounding GO:0009611 254 0.018
vesicle mediated transport GO:0016192 181 0.018
ras protein signal transduction GO:0007265 29 0.018
negative regulation of response to stimulus GO:0048585 155 0.018
cellular amino acid metabolic process GO:0006520 107 0.018
regulation of phosphorus metabolic process GO:0051174 349 0.018
regulation of catalytic activity GO:0050790 304 0.017
response to vitamin e GO:0033197 24 0.017
neuron differentiation GO:0030182 368 0.017
voluntary skeletal muscle contraction GO:0003010 3 0.017
cellular response to extracellular stimulus GO:0031668 73 0.017
cellular response to hormone stimulus GO:0032870 247 0.017
regulation of cellular component biogenesis GO:0044087 86 0.017
glucan metabolic process GO:0044042 23 0.017
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 27 0.017
stress activated protein kinase signaling cascade GO:0031098 37 0.017
organic acid metabolic process GO:0006082 292 0.017
female gonad development GO:0008585 53 0.017
sequestering of metal ion GO:0051238 9 0.017
Human Rat
regulation of immune system process GO:0002682 123 0.017
monovalent inorganic cation transport GO:0015672 172 0.017
regulation of anatomical structure size GO:0090066 135 0.016
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.016
maintenance of location GO:0051235 17 0.016
Human Rat
positive regulation of biosynthetic process GO:0009891 319 0.016
positive regulation of blood circulation GO:1903524 65 0.016
regulation of transcription dna templated GO:0006355 374 0.016
potassium ion transmembrane transport GO:0071805 71 0.016
leydig cell differentiation GO:0033327 8 0.016
signal transduction by phosphorylation GO:0023014 144 0.016
cation transmembrane transport GO:0098655 263 0.016
negative regulation of hormone secretion GO:0046888 46 0.016
male gamete generation GO:0048232 99 0.016
cell growth GO:0016049 104 0.016
axonogenesis GO:0007409 71 0.016
spermatogenesis GO:0007283 99 0.016
release of sequestered calcium ion into cytosol GO:0051209 25 0.016
protein oligomerization GO:0051259 191 0.016
ossification GO:0001503 70 0.015
developmental induction GO:0031128 2 0.015
macromolecular complex subunit organization GO:0043933 339 0.015
Human
positive regulation of transcription dna templated GO:0045893 197 0.015
erythrocyte differentiation GO:0030218 1 0.015
development of primary male sexual characteristics GO:0046546 59 0.015
positive regulation of protein kinase activity GO:0045860 73 0.015
protein homooligomerization GO:0051260 91 0.015
regulation of ion homeostasis GO:2000021 63 0.015
regulation of protein serine threonine kinase activity GO:0071900 64 0.015
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.015
reactive oxygen species metabolic process GO:0072593 37 0.015
negative regulation of cell growth involved in cardiac muscle cell development GO:0061052 1 0.015
striated muscle cell differentiation GO:0051146 39 0.015
smooth muscle cell proliferation GO:0048659 77 0.015
positive regulation of phosphorus metabolic process GO:0010562 262 0.015
positive regulation of kinase activity GO:0033674 77 0.015
sequestering of calcium ion GO:0051208 8 0.015
Human Rat
regulation of protein metabolic process GO:0051246 289 0.015
multi organism reproductive process GO:0044703 262 0.015
myosin filament assembly GO:0031034 1 0.015
cell migration GO:0016477 197 0.014
membrane depolarization during cardiac muscle cell action potential GO:0086012 1 0.014
calcium mediated signaling GO:0019722 23 0.014
nucleoside monophosphate metabolic process GO:0009123 93 0.014
regulation of blood pressure GO:0008217 83 0.014
organ induction GO:0001759 1 0.014
negative regulation of metabolic process GO:0009892 331 0.014
positive regulation of atpase activity GO:0032781 6 0.014
insulin like growth factor receptor signaling pathway GO:0048009 3 0.014
membrane organization GO:0061024 94 0.014
negative regulation of cell death GO:0060548 229 0.014
muscle cell proliferation GO:0033002 84 0.014
cellular polysaccharide metabolic process GO:0044264 23 0.014
positive regulation of protein modification process GO:0031401 142 0.014
regulation of intracellular signal transduction GO:1902531 218 0.014
regulation of ion transmembrane transporter activity GO:0032412 48 0.014
positive regulation of phagocytosis engulfment GO:0060100 4 0.014
sexual reproduction GO:0019953 148 0.014
response to external biotic stimulus GO:0043207 221 0.014
peptide secretion GO:0002790 86 0.014
transcription from rna polymerase ii promoter GO:0006366 252 0.013
rna metabolic process GO:0016070 406 0.013
response to reactive oxygen species GO:0000302 120 0.013
positive regulation of molecular function GO:0044093 230 0.013
energy derivation by oxidation of organic compounds GO:0015980 46 0.013
cellular response to nutrient levels GO:0031669 60 0.013
alcohol biosynthetic process GO:0046165 38 0.013
regulation of nucleoside metabolic process GO:0009118 66 0.013
regulation of calcium ion transport into cytosol GO:0010522 25 0.013
regulation of cell development GO:0060284 263 0.013
cellular response to ketone GO:1901655 51 0.013
cytosolic calcium ion transport GO:0060401 39 0.013
organic acid transport GO:0015849 116 0.013
positive regulation of cell projection organization GO:0031346 111 0.013
actin filament organization GO:0007015 42 0.013
response to insulin GO:0032868 133 0.013
embryonic hindlimb morphogenesis GO:0035116 2 0.013
regulation of protein phosphorylation GO:0001932 183 0.013
carbohydrate biosynthetic process GO:0016051 42 0.013
intracellular transport GO:0046907 185 0.013
amine metabolic process GO:0009308 38 0.013
regulation of rna metabolic process GO:0051252 391 0.013
response to ethanol GO:0045471 162 0.013
regulation of cell migration GO:0030334 128 0.013
negative regulation of organ growth GO:0046621 3 0.013
biological adhesion GO:0022610 110 0.013
limb morphogenesis GO:0035108 4 0.013
male germ line stem cell asymmetric division GO:0048133 1 0.013
positive regulation of mapk cascade GO:0043410 92 0.013
positive regulation of ion transport GO:0043270 94 0.013
cellular component assembly involved in morphogenesis GO:0010927 17 0.013
syncytium formation GO:0006949 4 0.012
negative regulation of secretion by cell GO:1903531 72 0.012
neuronal action potential GO:0019228 35 0.012
positive regulation of rna metabolic process GO:0051254 203 0.012
regulation of cellular amino acid metabolic process GO:0006521 2 0.012
neuron projection development GO:0031175 273 0.012
central nervous system development GO:0007417 311 0.012
tissue regeneration GO:0042246 36 0.012
cellular response to mechanical stimulus GO:0071260 48 0.012
positive regulation of nervous system development GO:0051962 178 0.012
regulation of stem cell differentiation GO:2000736 2 0.012
cellular glucan metabolic process GO:0006073 23 0.012
energy reserve metabolic process GO:0006112 25 0.012
sarcomere organization GO:0045214 6 0.012
developmental growth GO:0048589 100 0.012
potassium ion transport GO:0006813 97 0.012
negative regulation of signal transduction GO:0009968 83 0.012
response to alkaloid GO:0043279 132 0.012
Human
rhythmic process GO:0048511 156 0.012
positive regulation of rna biosynthetic process GO:1902680 197 0.012
cell cell signaling involved in cell fate commitment GO:0045168 2 0.012
endocrine hormone secretion GO:0060986 21 0.012
synaptic transmission GO:0007268 235 0.012

Casq2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.965
cardiovascular system disease DOID:1287 0 0.965
myopathy DOID:423 0 0.949
muscular disease DOID:0080000 0 0.949
musculoskeletal system disease DOID:17 0 0.949
muscle tissue disease DOID:66 0 0.949
heart disease DOID:114 0 0.924
cardiomyopathy DOID:0050700 0 0.924
intrinsic cardiomyopathy DOID:0060036 0 0.846
dilated cardiomyopathy DOID:12930 0 0.704
congenital heart disease DOID:1682 0 0.327
heart septal defect DOID:1681 0 0.327
hypertrophic cardiomyopathy DOID:11984 0 0.208
muscular dystrophy DOID:9884 0 0.134
long qt syndrome DOID:2843 0 0.043
disease of metabolism DOID:0014667 0 0.038
nervous system disease DOID:863 0 0.026
heart conduction disease DOID:10273 0 0.026
urinary system disease DOID:18 0 0.017
arrhythmogenic right ventricular cardiomyopathy DOID:0050431 0 0.017
nutrition disease DOID:374 0 0.016
acquired metabolic disease DOID:0060158 0 0.016
inherited metabolic disorder DOID:655 0 0.014
central nervous system disease DOID:331 0 0.013
obesity DOID:9970 0 0.013
overnutrition DOID:654 0 0.013