Rattus norvegicus

23 known processes

Plcb4

phospholipase C, beta 4

(Aliases: RATBETA4AA,Beta4aa)

Plcb4 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
oxoacid metabolic process GO:0043436 290 0.064
carboxylic acid metabolic process GO:0019752 289 0.057
transmembrane transport GO:0055085 412 0.048
Rat
intracellular signal transduction GO:0035556 314 0.037
Rat
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.037
cellular amine metabolic process GO:0044106 38 0.037
carbohydrate derivative metabolic process GO:1901135 346 0.037
multicellular organismal signaling GO:0035637 44 0.036
rna biosynthetic process GO:0032774 380 0.035
macromolecular complex assembly GO:0065003 273 0.034
neurological system process GO:0050877 219 0.033
Rat Fly
negative regulation of macromolecule metabolic process GO:0010605 260 0.033
regulation of cell proliferation GO:0042127 359 0.033
Worm
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.032
protein phosphorylation GO:0006468 345 0.032
organic acid metabolic process GO:0006082 292 0.032
central nervous system development GO:0007417 311 0.031
action potential GO:0001508 54 0.031
inorganic cation transmembrane transport GO:0098662 202 0.030
Rat
cellular response to oxygen containing compound GO:1901701 386 0.030
cellular ketone metabolic process GO:0042180 51 0.029
inorganic ion transmembrane transport GO:0098660 229 0.029
Rat
regulation of cellular amine metabolic process GO:0033238 8 0.029
single organism biosynthetic process GO:0044711 342 0.028
Rat
positive regulation of gene expression GO:0010628 244 0.028
regulation of transcription dna templated GO:0006355 374 0.028
circulatory system process GO:0003013 183 0.027
protein complex subunit organization GO:0071822 302 0.027
neuronal action potential GO:0019228 35 0.027
rna metabolic process GO:0016070 406 0.026
lipid metabolic process GO:0006629 283 0.026
Rat Fly
transcription dna templated GO:0006351 377 0.026
response to decreased oxygen levels GO:0036293 237 0.026
metal ion transport GO:0030001 289 0.026
regulation of cellular ketone metabolic process GO:0010565 27 0.025
positive regulation of cellular biosynthetic process GO:0031328 295 0.025
Rat
cellular amino acid metabolic process GO:0006520 107 0.025
positive regulation of cell proliferation GO:0008284 249 0.025
regulation of membrane potential GO:0042391 110 0.025
regulation of rna biosynthetic process GO:2001141 381 0.024
regulation of rna metabolic process GO:0051252 391 0.024
protein complex assembly GO:0006461 263 0.024
cellular response to nitrogen compound GO:1901699 210 0.024
amine metabolic process GO:0009308 38 0.024
organophosphate metabolic process GO:0019637 370 0.024
Rat Fly
potassium ion transport GO:0006813 97 0.024
negative regulation of gene expression GO:0010629 199 0.024
cellular component biogenesis GO:0044085 368 0.023
regulation of cellular amino acid metabolic process GO:0006521 2 0.023
cation transmembrane transport GO:0098655 263 0.023
Rat
protein complex biogenesis GO:0070271 263 0.022
transcription from rna polymerase ii promoter GO:0006366 252 0.022
cation transport GO:0006812 382 0.022
muscle system process GO:0003012 115 0.022
cellular response to hormone stimulus GO:0032870 247 0.022
chemical homeostasis GO:0048878 292 0.022
Rat
macromolecular complex subunit organization GO:0043933 339 0.022
blood circulation GO:0008015 183 0.022
positive regulation of cell development GO:0010720 176 0.022
head development GO:0060322 247 0.022
positive regulation of multicellular organismal process GO:0051240 387 0.022
Rat
positive regulation of biosynthetic process GO:0009891 319 0.021
Rat
ion transmembrane transport GO:0034220 365 0.021
Rat
cellular response to organonitrogen compound GO:0071417 197 0.021
single organism catabolic process GO:0044712 283 0.021
Rat
regulation of nucleic acid templated transcription GO:1903506 380 0.021
negative regulation of metabolic process GO:0009892 331 0.021
monovalent inorganic cation transport GO:0015672 172 0.021
regulation of phosphorylation GO:0042325 248 0.021
positive regulation of molecular function GO:0044093 230 0.021
response to nutrient levels GO:0031667 370 0.021
cellular component assembly GO:0022607 360 0.020
regulation of cell development GO:0060284 263 0.020
Fly
positive regulation of cellular amine metabolic process GO:0033240 3 0.020
response to extracellular stimulus GO:0009991 380 0.020
positive regulation of neurogenesis GO:0050769 165 0.020
response to inorganic substance GO:0010035 377 0.019
Rat
transmission of nerve impulse GO:0019226 42 0.019
response to carbohydrate GO:0009743 183 0.019
Rat
regulation of programmed cell death GO:0043067 341 0.019
Fly
homeostatic process GO:0042592 331 0.019
Rat Fly
cell projection organization GO:0030030 302 0.019
cellular lipid metabolic process GO:0044255 208 0.019
Rat Fly
secretion GO:0046903 307 0.019
Rat Worm
response to oxygen levels GO:0070482 265 0.019
Rat
rhythmic process GO:0048511 156 0.018
Fly
muscle contraction GO:0006936 88 0.018
regulation of protein modification process GO:0031399 194 0.018
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.018
cell cell signaling GO:0007267 335 0.017
Worm
neuron projection development GO:0031175 273 0.017
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.017
regulation of system process GO:0044057 208 0.017
reproductive process GO:0022414 372 0.017
Worm
negative regulation of cellular metabolic process GO:0031324 281 0.017
regulation of protein phosphorylation GO:0001932 183 0.017
nucleobase containing small molecule metabolic process GO:0055086 316 0.017
response to acid chemical GO:0001101 222 0.017
Rat
cellular chemical homeostasis GO:0055082 247 0.017
Rat
response to monosaccharide GO:0034284 159 0.017
Rat
synaptic transmission GO:0007268 235 0.017
Worm
cellular response to endogenous stimulus GO:0071495 377 0.017
nucleoside phosphate metabolic process GO:0006753 283 0.016
ensheathment of neurons GO:0007272 40 0.016
cellular ion homeostasis GO:0006873 184 0.016
Rat
cellular homeostasis GO:0019725 252 0.016
Rat
ribose phosphate metabolic process GO:0019693 235 0.016
regulation of metal ion transport GO:0010959 118 0.016
positive regulation of nervous system development GO:0051962 178 0.016
purine ribonucleotide metabolic process GO:0009150 227 0.016
regulation of molecular function GO:0065009 398 0.016
Rat
response to estrogen GO:0043627 232 0.016
positive regulation of phosphorus metabolic process GO:0010562 262 0.016
Rat
purine containing compound metabolic process GO:0072521 253 0.015
ras protein signal transduction GO:0007265 29 0.015
metal ion homeostasis GO:0055065 186 0.015
Rat
organelle organization GO:0006996 266 0.015
Worm
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.015
response to hypoxia GO:0001666 231 0.015
purine nucleotide metabolic process GO:0006163 229 0.015
regulation of secretion GO:0051046 224 0.015
Rat Worm
response to wounding GO:0009611 254 0.015
response to growth factor GO:0070848 189 0.015
positive regulation of developmental process GO:0051094 283 0.015
nucleotide metabolic process GO:0009117 279 0.014
positive regulation of cell differentiation GO:0045597 217 0.014
brain development GO:0007420 247 0.014
cellular response to peptide GO:1901653 133 0.014
response to purine containing compound GO:0014074 126 0.014
Rat
negative regulation of molecular function GO:0044092 133 0.014
cellular divalent inorganic cation homeostasis GO:0072503 162 0.014
Rat
signal release GO:0023061 145 0.014
Worm
divalent inorganic cation homeostasis GO:0072507 165 0.014
Rat
anatomical structure morphogenesis GO:0009653 298 0.014
Fly
inflammatory response GO:0006954 150 0.014
regulation of nervous system development GO:0051960 264 0.014
response to peptide GO:1901652 292 0.014
Rat
positive regulation of cellular component organization GO:0051130 200 0.014
carbohydrate derivative biosynthetic process GO:1901137 124 0.014
glycosyl compound metabolic process GO:1901657 182 0.014
positive regulation of cellular component movement GO:0051272 102 0.014
Rat
protein heterooligomerization GO:0051291 89 0.014
regulation of cellular localization GO:0060341 263 0.014
Rat Worm
positive regulation of cell projection organization GO:0031346 111 0.014
protein oligomerization GO:0051259 191 0.013
nitrogen compound transport GO:0071705 229 0.013
Rat Worm
ion homeostasis GO:0050801 212 0.013
Rat
mesoderm development GO:0007498 2 0.013
multicellular organismal reproductive process GO:0048609 233 0.013
Worm
calcium ion homeostasis GO:0055074 162 0.013
Rat
reproduction GO:0000003 245 0.013
Worm
negative regulation of biosynthetic process GO:0009890 168 0.013
regulation of blood circulation GO:1903522 110 0.013
regulation of muscle system process GO:0090257 79 0.013
positive regulation of transport GO:0051050 245 0.013
Rat Worm
adult locomotory behavior GO:0008344 4 0.013
Fly
organonitrogen compound catabolic process GO:1901565 179 0.013
ribonucleoside metabolic process GO:0009119 174 0.013
tissue development GO:0009888 252 0.013
neuron development GO:0048666 286 0.013
small gtpase mediated signal transduction GO:0007264 36 0.013
negative regulation of protein metabolic process GO:0051248 114 0.013
negative regulation of nucleic acid templated transcription GO:1903507 117 0.013
single organism reproductive process GO:0044702 297 0.013
Worm
cellular cation homeostasis GO:0030003 180 0.013
Rat
actin filament based process GO:0030029 86 0.013
regulation of ion transmembrane transport GO:0034765 121 0.013
Rat
regulation of multicellular organismal development GO:2000026 376 0.013
Fly
regulation of phosphate metabolic process GO:0019220 349 0.013
Rat
purine nucleoside metabolic process GO:0042278 169 0.013
regulation of apoptotic process GO:0042981 335 0.012
ribonucleotide metabolic process GO:0009259 231 0.012
cellular component movement GO:0006928 248 0.012
Rat
secretion by cell GO:0032940 248 0.012
Rat Worm
response to ethanol GO:0045471 162 0.012
regulation of neurogenesis GO:0050767 247 0.012
nucleic acid templated transcription GO:0097659 379 0.012
regulation of cellular catabolic process GO:0031329 101 0.012
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.012
multicellular organism growth GO:0035264 1 0.012
calcium ion transport GO:0006816 131 0.012
Rat
cellular metal ion homeostasis GO:0006875 172 0.012
Rat
negative regulation of transcription dna templated GO:0045892 116 0.012
organic substance catabolic process GO:1901575 316 0.012
Rat Worm
response to nutrient GO:0007584 248 0.012
positive regulation of cytosolic calcium ion concentration GO:0007204 122 0.012
Rat
oxidation reduction process GO:0055114 304 0.012
regeneration GO:0031099 163 0.012
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.012
regulation of signal transduction GO:0009966 318 0.012
Fly
response to glucose GO:0009749 136 0.012
cell migration GO:0016477 197 0.012
Rat
axis specification GO:0009798 4 0.012
single organism organelle organization GO:1902589 180 0.012
response to oxidative stress GO:0006979 186 0.012
Rat
positive regulation of neuron differentiation GO:0045666 126 0.012
positive regulation of rna metabolic process GO:0051254 203 0.011
regulation of homeostatic process GO:0032844 101 0.011
regulation of cellular component movement GO:0051270 150 0.011
Rat
regulation of anatomical structure size GO:0090066 135 0.011
regulation of transmembrane transport GO:0034762 122 0.011
Rat
establishment of protein localization GO:0045184 141 0.011
Rat
reactive oxygen species metabolic process GO:0072593 37 0.011
negative regulation of cell death GO:0060548 229 0.011
Fly
response to hexose GO:0009746 144 0.011
divalent metal ion transport GO:0070838 132 0.011
Rat
response to metal ion GO:0010038 253 0.011
Rat
neuron projection morphogenesis GO:0048812 122 0.011
response to vitamin GO:0033273 131 0.011
male mating behavior GO:0060179 3 0.011
Worm
regulation of secretion by cell GO:1903530 208 0.011
Rat Worm
glucose homeostasis GO:0042593 75 0.011
multicellular organism reproduction GO:0032504 233 0.011
Worm
regulation of neuron death GO:1901214 115 0.011
neuron apoptotic process GO:0051402 88 0.011
peptidyl amino acid modification GO:0018193 126 0.011
positive regulation of response to stimulus GO:0048584 285 0.011
eye morphogenesis GO:0048592 4 0.011
Fly
monocarboxylic acid metabolic process GO:0032787 152 0.011
positive regulation of rna biosynthetic process GO:1902680 197 0.011
regulation of cell differentiation GO:0045595 320 0.011
Fly
cation homeostasis GO:0055080 195 0.011
Rat
regulation of hormone levels GO:0010817 187 0.011
cell adhesion GO:0007155 110 0.011
phasic smooth muscle contraction GO:0014821 3 0.011
aging GO:0007568 241 0.011
Worm
purine containing compound catabolic process GO:0072523 138 0.011
maintenance of location GO:0051235 17 0.011
regulation of ion transmembrane transporter activity GO:0032412 48 0.011
Rat
behavior GO:0007610 205 0.011
Rat Worm Fly
neuron death GO:0070997 127 0.010
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.010
organophosphate biosynthetic process GO:0090407 143 0.010
Rat
multi multicellular organism process GO:0044706 138 0.010
Worm
positive regulation of nucleic acid templated transcription GO:1903508 197 0.010
regulation of cellular component organization GO:0051128 368 0.010
Worm
biological adhesion GO:0022610 110 0.010
single organism behavior GO:0044708 130 0.010
Rat Fly
myelination GO:0042552 39 0.010
regulation of nucleoside metabolic process GO:0009118 66 0.010
heterocycle catabolic process GO:0046700 167 0.010
ribonucleoside triphosphate catabolic process GO:0009203 122 0.010
regulation of cellular protein metabolic process GO:0032268 267 0.010
regulation of catabolic process GO:0009894 113 0.010
regulation of nucleotide metabolic process GO:0006140 117 0.010

Plcb4 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.033
nervous system disease DOID:863 0 0.033
sensory system disease DOID:0050155 0 0.015
eye and adnexa disease DOID:1492 0 0.012
eye disease DOID:5614 0 0.012
cardiovascular system disease DOID:1287 0 0.010