Rattus norvegicus

0 known processes

Oas2

2'-5' oligoadenylate synthetase 2

Oas2 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
protein phosphorylation GO:0006468 345 0.041
cellular amino acid metabolic process GO:0006520 107 0.039
organic acid metabolic process GO:0006082 292 0.036
oxoacid metabolic process GO:0043436 290 0.034
carboxylic acid metabolic process GO:0019752 289 0.034
cellular ketone metabolic process GO:0042180 51 0.032
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.032
intracellular signal transduction GO:0035556 314 0.032
regulation of cellular amino acid metabolic process GO:0006521 2 0.031
macromolecular complex subunit organization GO:0043933 339 0.030
regulation of protein metabolic process GO:0051246 289 0.030
amine metabolic process GO:0009308 38 0.030
regulation of cellular amine metabolic process GO:0033238 8 0.030
regulation of rna metabolic process GO:0051252 391 0.030
cellular amine metabolic process GO:0044106 38 0.030
response to nutrient levels GO:0031667 370 0.029
rna biosynthetic process GO:0032774 380 0.029
transcription dna templated GO:0006351 377 0.029
regulation of nucleic acid templated transcription GO:1903506 380 0.029
neuron differentiation GO:0030182 368 0.029
regulation of molecular function GO:0065009 398 0.029
organophosphate metabolic process GO:0019637 370 0.028
cellular component biogenesis GO:0044085 368 0.028
regulation of phosphate metabolic process GO:0019220 349 0.028
regulation of cellular ketone metabolic process GO:0010565 27 0.028
regulation of phosphorus metabolic process GO:0051174 349 0.028
regulation of transcription dna templated GO:0006355 374 0.028
programmed cell death GO:0012501 392 0.028
homeostatic process GO:0042592 331 0.028
regulation of cellular protein metabolic process GO:0032268 267 0.028
cellular response to endogenous stimulus GO:0071495 377 0.028
single organism biosynthetic process GO:0044711 342 0.028
response to extracellular stimulus GO:0009991 380 0.027
response to inorganic substance GO:0010035 377 0.027
negative regulation of metabolic process GO:0009892 331 0.027
apoptotic process GO:0006915 381 0.027
neuron projection development GO:0031175 273 0.027
regulation of programmed cell death GO:0043067 341 0.027
rna metabolic process GO:0016070 406 0.027
cell projection organization GO:0030030 302 0.027
cellular response to oxygen containing compound GO:1901701 386 0.026
carbohydrate derivative metabolic process GO:1901135 346 0.026
regulation of phosphorylation GO:0042325 248 0.026
regulation of cellular component organization GO:0051128 368 0.026
nucleic acid templated transcription GO:0097659 379 0.025
positive regulation of cellular biosynthetic process GO:0031328 295 0.025
cellular component assembly GO:0022607 360 0.025
regulation of rna biosynthetic process GO:2001141 381 0.025
reproductive process GO:0022414 372 0.025
organelle organization GO:0006996 266 0.025
regulation of apoptotic process GO:0042981 335 0.025
macromolecular complex assembly GO:0065003 273 0.024
negative regulation of cellular metabolic process GO:0031324 281 0.024
positive regulation of biosynthetic process GO:0009891 319 0.024
positive regulation of multicellular organismal process GO:0051240 387 0.024
cation transport GO:0006812 382 0.024
cellular response to stress GO:0033554 269 0.024
multi organism reproductive process GO:0044703 262 0.024
cellular component movement GO:0006928 248 0.024
regulation of multicellular organismal development GO:2000026 376 0.024
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.023
positive regulation of response to stimulus GO:0048584 285 0.023
single organism reproductive process GO:0044702 297 0.023
protein complex assembly GO:0006461 263 0.023
negative regulation of natural killer cell mediated cytotoxicity GO:0045953 4 0.023
positive regulation of cell proliferation GO:0008284 249 0.023
regulation of signal transduction GO:0009966 318 0.023
protein complex subunit organization GO:0071822 302 0.023
transmembrane transport GO:0055085 412 0.023
chemical homeostasis GO:0048878 292 0.023
reproduction GO:0000003 245 0.023
regulation of cell differentiation GO:0045595 320 0.022
central nervous system development GO:0007417 311 0.022
response to oxygen levels GO:0070482 265 0.022
positive regulation of developmental process GO:0051094 283 0.022
negative regulation of natural killer cell mediated immunity GO:0002716 4 0.022
regulation of protein modification process GO:0031399 194 0.022
regulation of protein phosphorylation GO:0001932 183 0.022
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.022
regulation of cell proliferation GO:0042127 359 0.021
protein complex biogenesis GO:0070271 263 0.021
cellular homeostasis GO:0019725 252 0.021
defense response GO:0006952 194 0.021
response to hypoxia GO:0001666 231 0.021
negative regulation of macromolecule metabolic process GO:0010605 260 0.021
nucleobase containing small molecule metabolic process GO:0055086 316 0.021
neuron development GO:0048666 286 0.021
response to decreased oxygen levels GO:0036293 237 0.021
positive regulation of phosphorus metabolic process GO:0010562 262 0.021
g protein coupled receptor signaling pathway GO:0007186 242 0.020
cellular response to organonitrogen compound GO:0071417 197 0.020
response to nutrient GO:0007584 248 0.020
cellular chemical homeostasis GO:0055082 247 0.020
nucleoside phosphate metabolic process GO:0006753 283 0.020
regulation of neurogenesis GO:0050767 247 0.020
brain development GO:0007420 247 0.020
metal ion transport GO:0030001 289 0.020
positive regulation of phosphate metabolic process GO:0045937 262 0.020
positive regulation of gene expression GO:0010628 244 0.020
positive regulation of cellular amine metabolic process GO:0033240 3 0.020
immune system process GO:0002376 204 0.020
regulation of cellular localization GO:0060341 263 0.020
cellular response to nitrogen compound GO:1901699 210 0.019
neurological system process GO:0050877 219 0.019
regulation of catalytic activity GO:0050790 304 0.019
multicellular organismal reproductive process GO:0048609 233 0.019
secretion GO:0046903 307 0.019
head development GO:0060322 247 0.019
negative regulation of innate immune response GO:0045824 4 0.019
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.019
catabolic process GO:0009056 351 0.019
cellular catabolic process GO:0044248 295 0.019
aging GO:0007568 241 0.019
nucleotide metabolic process GO:0009117 279 0.019
response to peptide GO:1901652 292 0.019
cellular ion homeostasis GO:0006873 184 0.019
regulation of nervous system development GO:0051960 264 0.019
regulation of intracellular signal transduction GO:1902531 218 0.019
regulation of cell development GO:0060284 263 0.018
response to estrogen GO:0043627 232 0.018
transcription from rna polymerase ii promoter GO:0006366 252 0.018
positive regulation of cell death GO:0010942 184 0.018
response to growth factor GO:0070848 189 0.018
response to oxidative stress GO:0006979 186 0.018
response to wounding GO:0009611 254 0.018
lipid metabolic process GO:0006629 283 0.018
multicellular organism reproduction GO:0032504 233 0.018
cell cell signaling GO:0007267 335 0.018
positive regulation of rna metabolic process GO:0051254 203 0.018
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.018
response to peptide hormone GO:0043434 278 0.018
response to acid chemical GO:0001101 222 0.018
cation homeostasis GO:0055080 195 0.018
positive regulation of rna biosynthetic process GO:1902680 197 0.018
response to ketone GO:1901654 182 0.018
cellular response to hormone stimulus GO:0032870 247 0.018
positive regulation of molecular function GO:0044093 230 0.018
response to cytokine GO:0034097 215 0.018
ion transmembrane transport GO:0034220 365 0.018
purine containing compound metabolic process GO:0072521 253 0.018
inorganic ion transmembrane transport GO:0098660 229 0.018
regulation of secretion by cell GO:1903530 208 0.017
macromolecule localization GO:0033036 252 0.017
positive regulation of protein metabolic process GO:0051247 178 0.017
ribose phosphate metabolic process GO:0019693 235 0.017
negative regulation of cell death GO:0060548 229 0.017
regulation of neuron differentiation GO:0045664 208 0.017
response to corticosteroid GO:0031960 235 0.017
cellular cation homeostasis GO:0030003 180 0.017
purine nucleotide metabolic process GO:0006163 229 0.017
positive regulation of phosphorylation GO:0042327 177 0.017
positive regulation of signaling GO:0023056 270 0.017
response to metal ion GO:0010038 253 0.017
metal ion homeostasis GO:0055065 186 0.017
cell motility GO:0048870 202 0.017
locomotion GO:0040011 237 0.017
cation transmembrane transport GO:0098655 263 0.017
single organism catabolic process GO:0044712 283 0.017
protein oligomerization GO:0051259 191 0.017
secretion by cell GO:0032940 248 0.017
positive regulation of cell differentiation GO:0045597 217 0.017
single organism organelle organization GO:1902589 180 0.016
anatomical structure morphogenesis GO:0009653 298 0.016
cellular calcium ion homeostasis GO:0006874 160 0.016
positive regulation of cell communication GO:0010647 271 0.016
positive regulation of cellular component organization GO:0051130 200 0.016
gland development GO:0048732 155 0.016
positive regulation of cellular protein metabolic process GO:0032270 167 0.016
ion homeostasis GO:0050801 212 0.016
positive regulation of transcription dna templated GO:0045893 197 0.016
cellular divalent inorganic cation homeostasis GO:0072503 162 0.016
response to carbohydrate GO:0009743 183 0.016
blood circulation GO:0008015 183 0.016
ras protein signal transduction GO:0007265 29 0.016
small gtpase mediated signal transduction GO:0007264 36 0.016
positive regulation of cell development GO:0010720 176 0.016
negative regulation of gene expression GO:0010629 199 0.015
purine ribonucleotide metabolic process GO:0009150 227 0.015
localization of cell GO:0051674 202 0.015
anterior posterior pattern specification GO:0009952 1 0.015
negative regulation of cell communication GO:0010648 158 0.015
positive regulation of programmed cell death GO:0043068 157 0.015
cellular response to growth factor stimulus GO:0071363 162 0.015
nitrogen compound transport GO:0071705 229 0.015
negative regulation of programmed cell death GO:0043069 183 0.015
negative regulation of response to stimulus GO:0048585 155 0.015
organophosphate biosynthetic process GO:0090407 143 0.015
positive regulation of nucleic acid templated transcription GO:1903508 197 0.015
response to external biotic stimulus GO:0043207 221 0.015
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.015
calcium ion homeostasis GO:0055074 162 0.015
response to glucocorticoid GO:0051384 223 0.015
developmental process involved in reproduction GO:0003006 159 0.015
divalent inorganic cation homeostasis GO:0072507 165 0.015
ribonucleotide metabolic process GO:0009259 231 0.015
immune response GO:0006955 104 0.015
response to ethanol GO:0045471 162 0.015
cellular metal ion homeostasis GO:0006875 172 0.015
regulation of secretion GO:0051046 224 0.015
positive regulation of apoptotic process GO:0043065 154 0.015
organic substance catabolic process GO:1901575 316 0.015
intracellular transport GO:0046907 185 0.015
regeneration GO:0031099 163 0.015
regulation of system process GO:0044057 208 0.014
regulation of neuron projection development GO:0010975 161 0.014
sexual reproduction GO:0019953 148 0.014
heart morphogenesis GO:0003007 3 0.014
positive regulation of nervous system development GO:0051962 178 0.014
positive regulation of protein modification process GO:0031401 142 0.014
negative regulation of apoptotic process GO:0043066 181 0.014
inflammatory response GO:0006954 150 0.014
axis specification GO:0009798 4 0.014
cell migration GO:0016477 197 0.014
organonitrogen compound biosynthetic process GO:1901566 167 0.014
negative regulation of signaling GO:0023057 157 0.014
circulatory system process GO:0003013 183 0.014
regulation of cell projection organization GO:0031344 175 0.014
carbohydrate derivative biosynthetic process GO:1901137 124 0.014
response to molecule of bacterial origin GO:0002237 194 0.014
response to toxic substance GO:0009636 133 0.014
negative regulation of molecular function GO:0044092 133 0.014
response to bacterium GO:0009617 200 0.014
regulation of anatomical structure size GO:0090066 135 0.014
positive regulation of intracellular signal transduction GO:1902533 138 0.014
positive regulation of catalytic activity GO:0043085 184 0.014
positive regulation of transport GO:0051050 245 0.014
cellular response to organic cyclic compound GO:0071407 202 0.014
synaptic transmission GO:0007268 235 0.014
regulation of hormone levels GO:0010817 187 0.013
negative regulation of biosynthetic process GO:0009890 168 0.013
cytosolic calcium ion homeostasis GO:0051480 140 0.013
negative regulation of multicellular organismal process GO:0051241 203 0.013
regulation of kinase activity GO:0043549 117 0.013
regulation of transferase activity GO:0051338 123 0.013
single organism intracellular transport GO:1902582 166 0.013
muscle system process GO:0003012 115 0.013
growth GO:0040007 165 0.013
response to biotic stimulus GO:0009607 226 0.013
multi multicellular organism process GO:0044706 138 0.013
cellular response to cytokine stimulus GO:0071345 127 0.013
positive regulation of neurogenesis GO:0050769 165 0.013
response to vitamin GO:0033273 131 0.013
small molecule biosynthetic process GO:0044283 124 0.013
oxidation reduction process GO:0055114 304 0.013
positive regulation of protein phosphorylation GO:0001934 135 0.013
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.013
heterocycle catabolic process GO:0046700 167 0.013
cellular protein localization GO:0034613 122 0.013
organic cyclic compound catabolic process GO:1901361 175 0.013
positive regulation of neuron differentiation GO:0045666 126 0.013
nucleobase containing compound catabolic process GO:0034655 152 0.013
nucleoside metabolic process GO:0009116 179 0.013
female pregnancy GO:0007565 122 0.013
monovalent inorganic cation transport GO:0015672 172 0.013
gamete generation GO:0007276 124 0.013
response to reactive oxygen species GO:0000302 120 0.013
protein localization GO:0008104 191 0.013
carbohydrate metabolic process GO:0005975 130 0.013
signal release GO:0023061 145 0.013
proteolysis GO:0006508 175 0.013
behavior GO:0007610 205 0.013
tissue development GO:0009888 252 0.013
response to other organism GO:0051707 220 0.013
single organism carbohydrate metabolic process GO:0044723 118 0.013
regulation of response to stress GO:0080134 126 0.013
cellular lipid metabolic process GO:0044255 208 0.013
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.012
response to monosaccharide GO:0034284 159 0.012
response to mechanical stimulus GO:0009612 134 0.012
response to hexose GO:0009746 144 0.012
cellular nitrogen compound catabolic process GO:0044270 163 0.012
regulation of immune system process GO:0002682 123 0.012
negative regulation of protein metabolic process GO:0051248 114 0.012
negative regulation of cellular biosynthetic process GO:0031327 161 0.012
gastrulation GO:0007369 2 0.012
action potential GO:0001508 54 0.012
peptidyl amino acid modification GO:0018193 126 0.012
response to radiation GO:0009314 137 0.012
ribonucleoside metabolic process GO:0009119 174 0.012
regulation of membrane potential GO:0042391 110 0.012
regulation of protein kinase activity GO:0045859 105 0.012
response to glucose GO:0009749 136 0.012
rhythmic process GO:0048511 156 0.012
purine ribonucleoside metabolic process GO:0046128 168 0.012
cellular response to peptide GO:1901653 133 0.012
negative regulation of transport GO:0051051 136 0.012
response to lipopolysaccharide GO:0032496 191 0.012
actin filament based process GO:0030029 86 0.012
cellular component morphogenesis GO:0032989 155 0.012
reproductive structure development GO:0048608 128 0.012
regulation of locomotion GO:0040012 148 0.012
cell activation GO:0001775 97 0.012
vascular process in circulatory system GO:0003018 96 0.012
anion transport GO:0006820 178 0.012
response to estradiol GO:0032355 164 0.012
cell type specific apoptotic process GO:0097285 134 0.012
negative regulation of rna metabolic process GO:0051253 123 0.012
reproductive system development GO:0061458 128 0.012
reactive nitrogen species metabolic process GO:2001057 1 0.012
negative regulation of cellular protein metabolic process GO:0032269 106 0.012
eye morphogenesis GO:0048592 4 0.012
cellular response to lipid GO:0071396 201 0.012
reactive oxygen species biosynthetic process GO:1903409 8 0.011
circulatory system development GO:0072359 134 0.011
organic hydroxy compound metabolic process GO:1901615 115 0.011
purine nucleoside metabolic process GO:0042278 169 0.011
positive regulation of signal transduction GO:0009967 175 0.011
glycosyl compound metabolic process GO:1901657 182 0.011
positive regulation of cytosolic calcium ion concentration GO:0007204 122 0.011
hormone transport GO:0009914 121 0.011
response to transition metal nanoparticle GO:1990267 122 0.011
positive regulation of secretion by cell GO:1903532 128 0.011
regulation of anatomical structure morphogenesis GO:0022603 141 0.011
organonitrogen compound catabolic process GO:1901565 179 0.011
protein transport GO:0015031 132 0.011
membrane organization GO:0061024 94 0.011
regulation of blood circulation GO:1903522 110 0.011
cellular macromolecule localization GO:0070727 122 0.011
cardiovascular system development GO:0072358 134 0.011
sex differentiation GO:0007548 113 0.011
wound healing GO:0042060 122 0.011
negative regulation of catalytic activity GO:0043086 103 0.011
limb morphogenesis GO:0035108 4 0.011
spermatogenesis GO:0007283 99 0.011
organ regeneration GO:0031100 101 0.011
cell morphogenesis GO:0000902 142 0.011
cytoplasmic transport GO:0016482 115 0.011
inorganic cation transmembrane transport GO:0098662 202 0.011
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.011
response to alkaloid GO:0043279 132 0.011
establishment of protein localization GO:0045184 141 0.011
divalent inorganic cation transport GO:0072511 134 0.011
appendage morphogenesis GO:0035107 4 0.011
cellular response to external stimulus GO:0071496 118 0.011
regulation of canonical wnt signaling pathway GO:0060828 4 0.011
regulation of hydrolase activity GO:0051336 143 0.011
reactive oxygen species metabolic process GO:0072593 37 0.011
cell morphogenesis involved in differentiation GO:0000904 119 0.011
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.011
purine containing compound catabolic process GO:0072523 138 0.011
hormone secretion GO:0046879 115 0.011
positive regulation of cell projection organization GO:0031346 111 0.011
sensory perception GO:0007600 101 0.011
lipid storage GO:0019915 1 0.011
cytoskeleton organization GO:0007010 111 0.011
aromatic compound catabolic process GO:0019439 168 0.011
negative regulation of rna biosynthetic process GO:1902679 118 0.011
organophosphate catabolic process GO:0046434 148 0.010
regulation of cell migration GO:0030334 128 0.010
cytokine biosynthetic process GO:0042089 3 0.010
cell projection morphogenesis GO:0048858 123 0.010
mapk cascade GO:0000165 140 0.010
nucleotide catabolic process GO:0009166 139 0.010
embryonic pattern specification GO:0009880 1 0.010
chromosome segregation GO:0007059 2 0.010
salivary gland development GO:0007431 3 0.010
development of primary sexual characteristics GO:0045137 107 0.010
regulation of ion transport GO:0043269 245 0.010
sequestering of metal ion GO:0051238 9 0.010
positive regulation of secretion GO:0051047 140 0.010
negative regulation of cell cycle phase transition GO:1901988 4 0.010
embryonic skeletal system morphogenesis GO:0048704 3 0.010
dna metabolic process GO:0006259 96 0.010
negative regulation of nucleic acid templated transcription GO:1903507 117 0.010
signal transduction by phosphorylation GO:0023014 144 0.010
leukocyte cell cell adhesion GO:0007159 4 0.010
nucleotide biosynthetic process GO:0009165 98 0.010
regulation of neuron death GO:1901214 115 0.010
lipid biosynthetic process GO:0008610 128 0.010
regulation of cellular component movement GO:0051270 150 0.010
neuron death GO:0070997 127 0.010

Oas2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.024
nervous system disease DOID:863 0 0.024
musculoskeletal system disease DOID:17 0 0.014
sensory system disease DOID:0050155 0 0.013
central nervous system disease DOID:331 0 0.011
disease of metabolism DOID:0014667 0 0.011