Rattus norvegicus

6 known processes

Pex6

peroxisomal biogenesis factor 6

(Aliases: Paf-2,Paf2)

Pex6 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
organic acid metabolic process GO:0006082 292 0.191
carboxylic acid metabolic process GO:0019752 289 0.190
single organism biosynthetic process GO:0044711 342 0.159
oxoacid metabolic process GO:0043436 290 0.152
regulation of rna biosynthetic process GO:2001141 381 0.128
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.113
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.103
regulation of transcription dna templated GO:0006355 374 0.102
rna metabolic process GO:0016070 406 0.097
regulation of nucleic acid templated transcription GO:1903506 380 0.097
nucleic acid templated transcription GO:0097659 379 0.095
rna biosynthetic process GO:0032774 380 0.090
regulation of molecular function GO:0065009 398 0.086
positive regulation of nucleic acid templated transcription GO:1903508 197 0.085
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.082
positive regulation of biosynthetic process GO:0009891 319 0.080
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.080
positive regulation of cellular biosynthetic process GO:0031328 295 0.078
neuron differentiation GO:0030182 368 0.076
transcription from rna polymerase ii promoter GO:0006366 252 0.076
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.075
response to extracellular stimulus GO:0009991 380 0.074
programmed cell death GO:0012501 392 0.072
regulation of rna metabolic process GO:0051252 391 0.072
lipid biosynthetic process GO:0008610 128 0.069
response to nutrient levels GO:0031667 370 0.069
positive regulation of rna biosynthetic process GO:1902680 197 0.064
positive regulation of transcription dna templated GO:0045893 197 0.063
transcription dna templated GO:0006351 377 0.063
positive regulation of gene expression GO:0010628 244 0.057
cellular amino acid metabolic process GO:0006520 107 0.056
lipid metabolic process GO:0006629 283 0.053
cellular ketone metabolic process GO:0042180 51 0.049
protein complex assembly GO:0006461 263 0.049
positive regulation of rna metabolic process GO:0051254 203 0.047
protein phosphorylation GO:0006468 345 0.047
cellular component biogenesis GO:0044085 368 0.046
regulation of programmed cell death GO:0043067 341 0.046
monocarboxylic acid metabolic process GO:0032787 152 0.045
regulation of cellular ketone metabolic process GO:0010565 27 0.045
negative regulation of cell death GO:0060548 229 0.045
cellular component movement GO:0006928 248 0.045
central nervous system development GO:0007417 311 0.044
carbohydrate derivative metabolic process GO:1901135 346 0.044
Human Yeast
carboxylic acid biosynthetic process GO:0046394 83 0.043
regulation of phosphorus metabolic process GO:0051174 349 0.042
nucleobase containing small molecule metabolic process GO:0055086 316 0.042
Human Yeast
apoptotic process GO:0006915 381 0.041
protein complex biogenesis GO:0070271 263 0.040
regulation of protein metabolic process GO:0051246 289 0.040
intracellular signal transduction GO:0035556 314 0.038
response to peptide GO:1901652 292 0.038
negative regulation of macromolecule metabolic process GO:0010605 260 0.037
cellular lipid metabolic process GO:0044255 208 0.037
catabolic process GO:0009056 351 0.037
Human Yeast
response to nutrient GO:0007584 248 0.037
fatty acid metabolic process GO:0006631 99 0.037
negative regulation of gene expression GO:0010629 199 0.036
regulation of multicellular organismal development GO:2000026 376 0.035
organic acid biosynthetic process GO:0016053 83 0.035
negative regulation of metabolic process GO:0009892 331 0.035
macromolecular complex assembly GO:0065003 273 0.035
regulation of apoptotic process GO:0042981 335 0.035
small molecule biosynthetic process GO:0044283 124 0.034
organic substance catabolic process GO:1901575 316 0.034
Human Yeast
organonitrogen compound biosynthetic process GO:1901566 167 0.033
response to wounding GO:0009611 254 0.032
negative regulation of cellular metabolic process GO:0031324 281 0.032
positive regulation of molecular function GO:0044093 230 0.031
oxidation reduction process GO:0055114 304 0.031
response to inorganic substance GO:0010035 377 0.031
cell projection organization GO:0030030 302 0.031
positive regulation of cell communication GO:0010647 271 0.031
regulation of signal transduction GO:0009966 318 0.030
neuron projection development GO:0031175 273 0.030
cellular component assembly GO:0022607 360 0.030
nitrogen compound transport GO:0071705 229 0.030
regulation of catalytic activity GO:0050790 304 0.029
amine metabolic process GO:0009308 38 0.029
negative regulation of programmed cell death GO:0043069 183 0.029
localization of cell GO:0051674 202 0.029
regulation of cellular amino acid metabolic process GO:0006521 2 0.029
negative regulation of molecular function GO:0044092 133 0.029
single organism catabolic process GO:0044712 283 0.029
Human Yeast
cofactor metabolic process GO:0051186 95 0.029
cellular amine metabolic process GO:0044106 38 0.029
cellular catabolic process GO:0044248 295 0.028
Human Yeast
anatomical structure morphogenesis GO:0009653 298 0.028
nucleotide metabolic process GO:0009117 279 0.028
Human Yeast
response to metal ion GO:0010038 253 0.028
regulation of cellular amine metabolic process GO:0033238 8 0.028
regulation of cell proliferation GO:0042127 359 0.028
purine containing compound metabolic process GO:0072521 253 0.028
Human Yeast
organophosphate metabolic process GO:0019637 370 0.027
Human Yeast
positive regulation of programmed cell death GO:0043068 157 0.027
regulation of protein modification process GO:0031399 194 0.027
aging GO:0007568 241 0.026
Yeast
regulation of cellular localization GO:0060341 263 0.026
positive regulation of phosphorylation GO:0042327 177 0.026
proteolysis GO:0006508 175 0.026
cellular response to oxygen containing compound GO:1901701 386 0.026
nucleoside metabolic process GO:0009116 179 0.025
Human Yeast
regulation of protein phosphorylation GO:0001932 183 0.025
positive regulation of phosphate metabolic process GO:0045937 262 0.025
positive regulation of signal transduction GO:0009967 175 0.025
regulation of nervous system development GO:0051960 264 0.025
positive regulation of apoptotic process GO:0043065 154 0.025
ribose phosphate metabolic process GO:0019693 235 0.024
Human Yeast
intracellular transport GO:0046907 185 0.024
Human Yeast
regulation of cell development GO:0060284 263 0.024
negative regulation of signaling GO:0023057 157 0.024
nucleoside phosphate metabolic process GO:0006753 283 0.024
Human Yeast
purine nucleotide metabolic process GO:0006163 229 0.024
Human Yeast
negative regulation of transcription dna templated GO:0045892 116 0.024
positive regulation of response to stimulus GO:0048584 285 0.024
positive regulation of cell death GO:0010942 184 0.024
macromolecular complex subunit organization GO:0043933 339 0.024
positive regulation of signaling GO:0023056 270 0.024
negative regulation of response to stimulus GO:0048585 155 0.024
protein oligomerization GO:0051259 191 0.024
cellular response to peptide hormone stimulus GO:0071375 120 0.023
response to carbohydrate GO:0009743 183 0.023
regulation of phosphorylation GO:0042325 248 0.023
growth GO:0040007 165 0.023
negative regulation of rna metabolic process GO:0051253 123 0.023
regulation of intracellular signal transduction GO:1902531 218 0.022
response to acid chemical GO:0001101 222 0.022
immune response GO:0006955 104 0.022
carbohydrate metabolic process GO:0005975 130 0.022
cellular response to hormone stimulus GO:0032870 247 0.022
positive regulation of multicellular organismal process GO:0051240 387 0.022
response to peptide hormone GO:0043434 278 0.022
regulation of hydrolase activity GO:0051336 143 0.022
response to oxidative stress GO:0006979 186 0.022
peptidyl amino acid modification GO:0018193 126 0.022
response to corticosteroid GO:0031960 235 0.022
cellular response to peptide GO:1901653 133 0.022
negative regulation of biosynthetic process GO:0009890 168 0.022
negative regulation of rna biosynthetic process GO:1902679 118 0.022
regulation of cell differentiation GO:0045595 320 0.021
neuron development GO:0048666 286 0.021
homeostatic process GO:0042592 331 0.021
positive regulation of catalytic activity GO:0043085 184 0.021
negative regulation of nucleic acid templated transcription GO:1903507 117 0.021
response to external biotic stimulus GO:0043207 221 0.021
g protein coupled receptor signaling pathway GO:0007186 242 0.021
purine ribonucleotide metabolic process GO:0009150 227 0.021
Human Yeast
secretion by cell GO:0032940 248 0.021
cellular response to lipid GO:0071396 201 0.020
negative regulation of cell communication GO:0010648 158 0.020
sulfur compound metabolic process GO:0006790 70 0.020
regulation of lipid metabolic process GO:0019216 68 0.020
single organism reproductive process GO:0044702 297 0.020
regulation of anatomical structure size GO:0090066 135 0.020
positive regulation of cellular amine metabolic process GO:0033240 3 0.020
regulation of hormone levels GO:0010817 187 0.020
locomotion GO:0040011 237 0.020
heart morphogenesis GO:0003007 3 0.020
regulation of cell projection organization GO:0031344 175 0.019
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.019
organophosphate biosynthetic process GO:0090407 143 0.019
response to mechanical stimulus GO:0009612 134 0.019
peptide transport GO:0015833 97 0.019
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.019
glycosyl compound metabolic process GO:1901657 182 0.019
Human Yeast
positive regulation of intracellular signal transduction GO:1902533 138 0.019
protein complex subunit organization GO:0071822 302 0.019
enzyme linked receptor protein signaling pathway GO:0007167 116 0.019
cellular component morphogenesis GO:0032989 155 0.019
response to oxygen levels GO:0070482 265 0.018
regulation of secretion by cell GO:1903530 208 0.018
positive regulation of developmental process GO:0051094 283 0.018
regulation of cellular protein metabolic process GO:0032268 267 0.018
negative regulation of multicellular organismal process GO:0051241 203 0.018
regulation of neuron differentiation GO:0045664 208 0.018
cell type specific apoptotic process GO:0097285 134 0.018
reproductive process GO:0022414 372 0.018
positive regulation of transferase activity GO:0051347 81 0.018
ribonucleoside metabolic process GO:0009119 174 0.018
Human Yeast
coenzyme metabolic process GO:0006732 86 0.018
organic cyclic compound catabolic process GO:1901361 175 0.018
Human Yeast
regulation of locomotion GO:0040012 148 0.018
response to glucose GO:0009749 136 0.018
monosaccharide metabolic process GO:0005996 61 0.018
response to hypoxia GO:0001666 231 0.018
carboxylic acid transport GO:0046942 115 0.018
macromolecule localization GO:0033036 252 0.018
Human Yeast
negative regulation of cellular protein metabolic process GO:0032269 106 0.018
cell cell signaling GO:0007267 335 0.017
organic acid transport GO:0015849 116 0.017
positive regulation of transport GO:0051050 245 0.017
organonitrogen compound catabolic process GO:1901565 179 0.017
Human Yeast
response to biotic stimulus GO:0009607 226 0.017
nucleotide catabolic process GO:0009166 139 0.017
Human Yeast
nucleoside triphosphate metabolic process GO:0009141 144 0.017
Human Yeast
response to lipopolysaccharide GO:0032496 191 0.017
secretion GO:0046903 307 0.017
cellular response to growth factor stimulus GO:0071363 162 0.017
cellular nitrogen compound catabolic process GO:0044270 163 0.017
Human Yeast
organophosphate catabolic process GO:0046434 148 0.017
Human Yeast
cell motility GO:0048870 202 0.017
regulation of cellular component organization GO:0051128 368 0.017
positive regulation of phosphorus metabolic process GO:0010562 262 0.017
regulation of cell migration GO:0030334 128 0.017
positive regulation of protein metabolic process GO:0051247 178 0.017
developmental process involved in reproduction GO:0003006 159 0.017
brain development GO:0007420 247 0.017
blood circulation GO:0008015 183 0.017
response to other organism GO:0051707 220 0.017
negative regulation of apoptotic process GO:0043066 181 0.017
regulation of anatomical structure morphogenesis GO:0022603 141 0.016
gonad development GO:0008406 104 0.016
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.016
hexose metabolic process GO:0019318 58 0.016
cell morphogenesis involved in neuron differentiation GO:0048667 106 0.016
cation transport GO:0006812 382 0.016
single organism intracellular transport GO:1902582 166 0.016
Human Yeast
cell morphogenesis involved in differentiation GO:0000904 119 0.016
sex differentiation GO:0007548 113 0.016
negative regulation of cellular biosynthetic process GO:0031327 161 0.016
response to reactive oxygen species GO:0000302 120 0.016
positive regulation of cell differentiation GO:0045597 217 0.016
cellular response to endogenous stimulus GO:0071495 377 0.016
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.016
negative regulation of transcription from rna polymerase ii promoter GO:0000122 75 0.016
carbohydrate derivative catabolic process GO:1901136 147 0.015
Human Yeast
multicellular organismal reproductive process GO:0048609 233 0.015
cellular response to external stimulus GO:0071496 118 0.015
positive regulation of protein phosphorylation GO:0001934 135 0.015
glycosyl compound catabolic process GO:1901658 126 0.015
Human Yeast
response to organophosphorus GO:0046683 102 0.015
purine ribonucleotide biosynthetic process GO:0009152 81 0.015
regulation of g0 to g1 transition GO:0070316 3 0.015
multicellular organism growth GO:0035264 1 0.015
nucleoside phosphate biosynthetic process GO:1901293 102 0.015
head development GO:0060322 247 0.015
ras protein signal transduction GO:0007265 29 0.015
negative regulation of phosphorus metabolic process GO:0010563 80 0.015
transmembrane transport GO:0055085 412 0.015
Human Yeast
cellular response to nitrogen compound GO:1901699 210 0.014
single organism carbohydrate metabolic process GO:0044723 118 0.014
regulation of phosphate metabolic process GO:0019220 349 0.014
positive regulation of cell proliferation GO:0008284 249 0.014
circulatory system process GO:0003013 183 0.014
intracellular protein transport GO:0006886 79 0.014
Human Yeast
protein autophosphorylation GO:0046777 66 0.014
negative regulation of cell proliferation GO:0008285 119 0.014
heterocycle catabolic process GO:0046700 167 0.014
Human Yeast
ribonucleoside catabolic process GO:0042454 126 0.014
Human Yeast
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.014
purine containing compound biosynthetic process GO:0072522 85 0.014
regulation of system process GO:0044057 208 0.014
nucleotide biosynthetic process GO:0009165 98 0.014
purine nucleoside metabolic process GO:0042278 169 0.014
Human Yeast
reproduction GO:0000003 245 0.014
cell migration GO:0016477 197 0.014
small gtpase mediated signal transduction GO:0007264 36 0.014
cellular response to insulin stimulus GO:0032869 81 0.014
positive regulation of cellular component organization GO:0051130 200 0.014
negative regulation of protein metabolic process GO:0051248 114 0.014
anion transport GO:0006820 178 0.014
positive regulation of protein modification process GO:0031401 142 0.014
negative regulation of catalytic activity GO:0043086 103 0.014
organelle organization GO:0006996 266 0.014
nucleocytoplasmic transport GO:0006913 48 0.013
protein localization GO:0008104 191 0.013
Human Yeast
hormone transport GO:0009914 121 0.013
positive regulation of cell development GO:0010720 176 0.013
nucleoside phosphate catabolic process GO:1901292 140 0.013
Human Yeast
nuclear transport GO:0051169 49 0.013
regulation of neuron projection development GO:0010975 161 0.013
response to purine containing compound GO:0014074 126 0.013
regulation of protein transport GO:0051223 68 0.013
response to molecule of bacterial origin GO:0002237 194 0.013
regulation of hormone secretion GO:0046883 106 0.013
defense response GO:0006952 194 0.013
regulation of peptide transport GO:0090087 87 0.013
purine containing compound catabolic process GO:0072523 138 0.013
Human Yeast
response to growth factor GO:0070848 189 0.013
regulation of homeostatic process GO:0032844 101 0.013
amide transport GO:0042886 105 0.013
ion transmembrane transport GO:0034220 365 0.013
cell morphogenesis GO:0000902 142 0.013
positive regulation of nf kappab import into nucleus GO:0042346 2 0.013
response to insulin GO:0032868 133 0.013
nucleoside catabolic process GO:0009164 126 0.013
Human Yeast
neuron projection morphogenesis GO:0048812 122 0.013
response to bacterium GO:0009617 200 0.013
antigen receptor mediated signaling pathway GO:0050851 1 0.013
regulation of membrane potential GO:0042391 110 0.013
regulation of cell motility GO:2000145 131 0.013
response to glucocorticoid GO:0051384 223 0.013
immune system process GO:0002376 204 0.013
regulation of growth GO:0040008 105 0.013
carbohydrate derivative biosynthetic process GO:1901137 124 0.013
glucose metabolic process GO:0006006 52 0.013
positive regulation of nervous system development GO:0051962 178 0.013
metal ion transport GO:0030001 289 0.013
regulation of kinase activity GO:0043549 117 0.012
regulation of lipid biosynthetic process GO:0046890 38 0.012
tissue development GO:0009888 252 0.012
cellular homeostasis GO:0019725 252 0.012
regulation of immune system process GO:0002682 123 0.012
behavior GO:0007610 205 0.012
response to decreased oxygen levels GO:0036293 237 0.012
synaptic transmission GO:0007268 235 0.012
response to monosaccharide GO:0034284 159 0.012
regulation of purine nucleotide metabolic process GO:1900542 115 0.012
establishment of protein localization GO:0045184 141 0.012
Human Yeast
regulation of neurogenesis GO:0050767 247 0.012
cellular response to cytokine stimulus GO:0071345 127 0.012
positive regulation of neuron differentiation GO:0045666 126 0.012
protein import GO:0017038 37 0.012
Human Yeast
signal release GO:0023061 145 0.012
ribose phosphate biosynthetic process GO:0046390 87 0.012
cellular response to stress GO:0033554 269 0.012
response to transition metal nanoparticle GO:1990267 122 0.012
reproductive system development GO:0061458 128 0.012
chemical homeostasis GO:0048878 292 0.012
negative regulation of transport GO:0051051 136 0.012
synaptic growth at neuromuscular junction GO:0051124 1 0.012
development of primary sexual characteristics GO:0045137 107 0.012
organic anion transport GO:0015711 132 0.012
nucleoside triphosphate catabolic process GO:0009143 123 0.012
Human Yeast
cellular response to abiotic stimulus GO:0071214 85 0.012
response to cytokine GO:0034097 215 0.012
positive regulation of cell migration GO:0030335 96 0.012
developmental growth GO:0048589 100 0.012
hormone secretion GO:0046879 115 0.011
reactive oxygen species biosynthetic process GO:1903409 8 0.011
cellular modified amino acid metabolic process GO:0006575 61 0.011
rhythmic process GO:0048511 156 0.011
positive regulation of immune system process GO:0002684 90 0.011
negative regulation of innate immune response GO:0045824 4 0.011
regeneration GO:0031099 163 0.011
regulation of transferase activity GO:0051338 123 0.011
cyclic nucleotide metabolic process GO:0009187 80 0.011
regulation of protein kinase activity GO:0045859 105 0.011
positive regulation of secretion by cell GO:1903532 128 0.011
regulation of secretion GO:0051046 224 0.011
response to vitamin GO:0033273 131 0.011
regulation of cellular component biogenesis GO:0044087 86 0.011
regulation of nucleotide metabolic process GO:0006140 117 0.011
single organism behavior GO:0044708 130 0.011
embryonic pattern specification GO:0009880 1 0.011
axis specification GO:0009798 4 0.011
protein processing GO:0016485 68 0.011
regulation of peptide secretion GO:0002791 82 0.011
positive regulation of neurogenesis GO:0050769 165 0.011
regulation of immunoglobulin production GO:0002637 4 0.011
fatty acid biosynthetic process GO:0006633 33 0.011
positive regulation of purine nucleotide metabolic process GO:1900544 91 0.011
single organism nuclear import GO:1902593 35 0.011
ribonucleotide biosynthetic process GO:0009260 85 0.011
reproductive structure development GO:0048608 128 0.011
regulation of blood circulation GO:1903522 110 0.011
monocarboxylic acid biosynthetic process GO:0072330 48 0.010
cellular response to organonitrogen compound GO:0071417 197 0.010
cognition GO:0050890 92 0.010
heart development GO:0007507 72 0.010
regulation of protein localization GO:0032880 81 0.010
nucleobase containing compound catabolic process GO:0034655 152 0.010
Human Yeast
adult locomotory behavior GO:0008344 4 0.010
protein import into nucleus GO:0006606 35 0.010
urogenital system development GO:0001655 78 0.010
actin filament based process GO:0030029 86 0.010
multicellular organism reproduction GO:0032504 233 0.010
purine nucleoside triphosphate metabolic process GO:0009144 141 0.010
Human Yeast
negative regulation of phosphate metabolic process GO:0045936 80 0.010

Pex6 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.028
nervous system disease DOID:863 0 0.028
disease of metabolism DOID:0014667 0 0.016
inherited metabolic disorder DOID:655 0 0.014
central nervous system disease DOID:331 0 0.013