Rattus norvegicus

0 known processes

Reg4

regenerating islet-derived family, member 4

Reg4 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
rna biosynthetic process GO:0032774 380 0.048
nucleic acid templated transcription GO:0097659 379 0.045
neuron differentiation GO:0030182 368 0.044
rna metabolic process GO:0016070 406 0.042
transcription dna templated GO:0006351 377 0.042
regulation of multicellular organismal development GO:2000026 376 0.042
carboxylic acid metabolic process GO:0019752 289 0.041
programmed cell death GO:0012501 392 0.040
organic acid metabolic process GO:0006082 292 0.039
reproductive process GO:0022414 372 0.039
regulation of transcription dna templated GO:0006355 374 0.038
oxoacid metabolic process GO:0043436 290 0.037
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.037
positive regulation of multicellular organismal process GO:0051240 387 0.035
regulation of cell differentiation GO:0045595 320 0.035
cellular component assembly GO:0022607 360 0.035
positive regulation of biosynthetic process GO:0009891 319 0.035
regulation of cell proliferation GO:0042127 359 0.034
regulation of rna biosynthetic process GO:2001141 381 0.034
positive regulation of cellular biosynthetic process GO:0031328 295 0.034
regulation of cell development GO:0060284 263 0.034
anatomical structure morphogenesis GO:0009653 298 0.033
regulation of apoptotic process GO:0042981 335 0.033
regulation of neurogenesis GO:0050767 247 0.032
regulation of nervous system development GO:0051960 264 0.032
cellular amino acid metabolic process GO:0006520 107 0.032
regulation of nucleic acid templated transcription GO:1903506 380 0.032
response to extracellular stimulus GO:0009991 380 0.032
positive regulation of developmental process GO:0051094 283 0.031
negative regulation of metabolic process GO:0009892 331 0.031
cellular response to oxygen containing compound GO:1901701 386 0.031
regulation of rna metabolic process GO:0051252 391 0.031
cellular component movement GO:0006928 248 0.030
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.030
head development GO:0060322 247 0.030
cell projection organization GO:0030030 302 0.030
single organism reproductive process GO:0044702 297 0.030
response to nutrient levels GO:0031667 370 0.029
cellular component biogenesis GO:0044085 368 0.029
response to oxygen levels GO:0070482 265 0.029
cellular amine metabolic process GO:0044106 38 0.028
regulation of molecular function GO:0065009 398 0.028
intracellular signal transduction GO:0035556 314 0.028
neuron projection development GO:0031175 273 0.027
negative regulation of cellular metabolic process GO:0031324 281 0.027
regulation of signal transduction GO:0009966 318 0.027
response to inorganic substance GO:0010035 377 0.027
transcription from rna polymerase ii promoter GO:0006366 252 0.027
single organism biosynthetic process GO:0044711 342 0.027
apoptotic process GO:0006915 381 0.027
positive regulation of gene expression GO:0010628 244 0.027
response to acid chemical GO:0001101 222 0.027
response to hypoxia GO:0001666 231 0.026
homeostatic process GO:0042592 331 0.026
positive regulation of cell differentiation GO:0045597 217 0.026
chemical homeostasis GO:0048878 292 0.026
cellular ketone metabolic process GO:0042180 51 0.026
regulation of neuron differentiation GO:0045664 208 0.026
negative regulation of macromolecule metabolic process GO:0010605 260 0.026
organophosphate metabolic process GO:0019637 370 0.026
regulation of phosphorus metabolic process GO:0051174 349 0.026
regulation of cellular amino acid metabolic process GO:0006521 2 0.025
neurological system process GO:0050877 219 0.025
positive regulation of nervous system development GO:0051962 178 0.025
cation transport GO:0006812 382 0.025
response to peptide hormone GO:0043434 278 0.025
regulation of programmed cell death GO:0043067 341 0.025
central nervous system development GO:0007417 311 0.025
neuron development GO:0048666 286 0.025
positive regulation of rna metabolic process GO:0051254 203 0.025
regulation of cellular component organization GO:0051128 368 0.025
protein complex subunit organization GO:0071822 302 0.025
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.025
secretion GO:0046903 307 0.024
reproduction GO:0000003 245 0.024
negative regulation of gene expression GO:0010629 199 0.024
multicellular organismal reproductive process GO:0048609 233 0.024
macromolecular complex subunit organization GO:0043933 339 0.024
positive regulation of phosphorus metabolic process GO:0010562 262 0.024
regulation of cellular amine metabolic process GO:0033238 8 0.024
amine metabolic process GO:0009308 38 0.024
nucleobase containing small molecule metabolic process GO:0055086 316 0.024
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.024
brain development GO:0007420 247 0.024
cellular ion homeostasis GO:0006873 184 0.023
regulation of cellular ketone metabolic process GO:0010565 27 0.023
positive regulation of response to stimulus GO:0048584 285 0.023
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.023
transmembrane transport GO:0055085 412 0.023
negative regulation of cell death GO:0060548 229 0.023
multicellular organism reproduction GO:0032504 233 0.023
regulation of catalytic activity GO:0050790 304 0.023
cellular homeostasis GO:0019725 252 0.023
positive regulation of transcription dna templated GO:0045893 197 0.023
cellular response to endogenous stimulus GO:0071495 377 0.023
response to estrogen GO:0043627 232 0.023
localization of cell GO:0051674 202 0.023
regulation of cell projection organization GO:0031344 175 0.023
response to metal ion GO:0010038 253 0.023
carbohydrate derivative metabolic process GO:1901135 346 0.022
positive regulation of cell development GO:0010720 176 0.022
positive regulation of neurogenesis GO:0050769 165 0.022
multi organism reproductive process GO:0044703 262 0.022
negative regulation of transport GO:0051051 136 0.022
ion homeostasis GO:0050801 212 0.022
regulation of protein metabolic process GO:0051246 289 0.022
regulation of neuron projection development GO:0010975 161 0.022
positive regulation of phosphate metabolic process GO:0045937 262 0.022
regulation of phosphate metabolic process GO:0019220 349 0.022
cellular metal ion homeostasis GO:0006875 172 0.022
protein phosphorylation GO:0006468 345 0.021
oxidation reduction process GO:0055114 304 0.021
nucleotide metabolic process GO:0009117 279 0.021
locomotion GO:0040011 237 0.021
organelle organization GO:0006996 266 0.021
cell motility GO:0048870 202 0.021
positive regulation of cell communication GO:0010647 271 0.021
negative regulation of programmed cell death GO:0043069 183 0.021
cellular chemical homeostasis GO:0055082 247 0.021
regulation of cellular protein metabolic process GO:0032268 267 0.021
macromolecular complex assembly GO:0065003 273 0.021
cell migration GO:0016477 197 0.021
positive regulation of rna biosynthetic process GO:1902680 197 0.020
metal ion transport GO:0030001 289 0.020
positive regulation of cellular component organization GO:0051130 200 0.020
response to peptide GO:1901652 292 0.020
ion transmembrane transport GO:0034220 365 0.020
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.020
synaptic transmission GO:0007268 235 0.020
positive regulation of molecular function GO:0044093 230 0.020
positive regulation of nucleic acid templated transcription GO:1903508 197 0.020
lipid metabolic process GO:0006629 283 0.020
secretion by cell GO:0032940 248 0.020
regulation of cellular localization GO:0060341 263 0.020
organic substance catabolic process GO:1901575 316 0.020
nucleoside phosphate metabolic process GO:0006753 283 0.019
heart morphogenesis GO:0003007 3 0.019
cellular catabolic process GO:0044248 295 0.019
positive regulation of cell proliferation GO:0008284 249 0.019
g protein coupled receptor signaling pathway GO:0007186 242 0.019
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.019
ribose phosphate metabolic process GO:0019693 235 0.019
cellular response to nitrogen compound GO:1901699 210 0.019
response to nutrient GO:0007584 248 0.019
regulation of anatomical structure morphogenesis GO:0022603 141 0.019
cellular cation homeostasis GO:0030003 180 0.019
single organism catabolic process GO:0044712 283 0.019
cation homeostasis GO:0055080 195 0.019
axis specification GO:0009798 4 0.019
catabolic process GO:0009056 351 0.019
divalent inorganic cation homeostasis GO:0072507 165 0.019
positive regulation of signaling GO:0023056 270 0.019
positive regulation of apoptotic process GO:0043065 154 0.019
cell cell signaling GO:0007267 335 0.019
cellular divalent inorganic cation homeostasis GO:0072503 162 0.019
cellular response to organonitrogen compound GO:0071417 197 0.018
positive regulation of cell projection organization GO:0031346 111 0.018
anterior posterior pattern specification GO:0009952 1 0.018
macromolecule localization GO:0033036 252 0.018
regulation of cell migration GO:0030334 128 0.018
response to decreased oxygen levels GO:0036293 237 0.018
response to glucocorticoid GO:0051384 223 0.018
cellular calcium ion homeostasis GO:0006874 160 0.018
regulation of intracellular signal transduction GO:1902531 218 0.018
negative regulation of apoptotic process GO:0043066 181 0.017
regulation of membrane potential GO:0042391 110 0.017
cellular response to lipid GO:0071396 201 0.017
calcium ion homeostasis GO:0055074 162 0.017
regulation of cellular component movement GO:0051270 150 0.017
intracellular transport GO:0046907 185 0.017
positive regulation of neuron differentiation GO:0045666 126 0.017
regulation of secretion GO:0051046 224 0.017
blood circulation GO:0008015 183 0.017
protein complex biogenesis GO:0070271 263 0.017
protein oligomerization GO:0051259 191 0.017
cell morphogenesis involved in differentiation GO:0000904 119 0.017
protein complex assembly GO:0006461 263 0.017
cellular response to hormone stimulus GO:0032870 247 0.017
purine ribonucleotide metabolic process GO:0009150 227 0.017
response to cytokine GO:0034097 215 0.017
regulation of phosphorylation GO:0042325 248 0.017
negative regulation of biosynthetic process GO:0009890 168 0.017
response to oxidative stress GO:0006979 186 0.017
response to carbohydrate GO:0009743 183 0.017
regulation of secretion by cell GO:1903530 208 0.017
sexual reproduction GO:0019953 148 0.017
response to corticosteroid GO:0031960 235 0.017
tissue development GO:0009888 252 0.017
response to molecule of bacterial origin GO:0002237 194 0.016
response to growth factor GO:0070848 189 0.016
ras protein signal transduction GO:0007265 29 0.016
cellular response to cytokine stimulus GO:0071345 127 0.016
metal ion homeostasis GO:0055065 186 0.016
positive regulation of cellular amine metabolic process GO:0033240 3 0.016
aging GO:0007568 241 0.016
cation transmembrane transport GO:0098655 263 0.016
positive regulation of cell death GO:0010942 184 0.016
cellular component morphogenesis GO:0032989 155 0.016
nitrogen compound transport GO:0071705 229 0.016
response to ethanol GO:0045471 162 0.016
protein localization GO:0008104 191 0.016
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.016
circulatory system process GO:0003013 183 0.016
response to vitamin GO:0033273 131 0.016
positive regulation of programmed cell death GO:0043068 157 0.016
regulation of system process GO:0044057 208 0.015
positive regulation of phosphorylation GO:0042327 177 0.015
response to estradiol GO:0032355 164 0.015
response to lipopolysaccharide GO:0032496 191 0.015
cellular response to stress GO:0033554 269 0.015
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.015
response to radiation GO:0009314 137 0.015
proteolysis GO:0006508 175 0.015
cellular lipid metabolic process GO:0044255 208 0.015
positive regulation of catalytic activity GO:0043085 184 0.015
small gtpase mediated signal transduction GO:0007264 36 0.015
regulation of ion transport GO:0043269 245 0.015
purine containing compound metabolic process GO:0072521 253 0.015
negative regulation of multicellular organismal process GO:0051241 203 0.015
embryonic skeletal system development GO:0048706 3 0.015
positive regulation of neuron projection development GO:0010976 99 0.015
cytosolic calcium ion homeostasis GO:0051480 140 0.015
inorganic ion transmembrane transport GO:0098660 229 0.015
divalent inorganic cation transport GO:0072511 134 0.015
positive regulation of transport GO:0051050 245 0.015
response to alkaloid GO:0043279 132 0.015
cellular response to growth factor stimulus GO:0071363 162 0.014
response to wounding GO:0009611 254 0.014
circulatory system development GO:0072359 134 0.014
purine nucleotide metabolic process GO:0006163 229 0.014
nucleoside metabolic process GO:0009116 179 0.014
negative regulation of cellular biosynthetic process GO:0031327 161 0.014
gamete generation GO:0007276 124 0.014
chromosome segregation GO:0007059 2 0.014
positive regulation of signal transduction GO:0009967 175 0.014
positive regulation of intracellular signal transduction GO:1902533 138 0.014
positive regulation of protein metabolic process GO:0051247 178 0.014
positive regulation of cytosolic calcium ion concentration GO:0007204 122 0.014
response to ketone GO:1901654 182 0.014
defense response GO:0006952 194 0.014
purine nucleoside metabolic process GO:0042278 169 0.014
growth GO:0040007 165 0.014
divalent metal ion transport GO:0070838 132 0.014
neuron projection morphogenesis GO:0048812 122 0.014
single organism intracellular transport GO:1902582 166 0.014
cellular response to organic cyclic compound GO:0071407 202 0.014
establishment of protein localization GO:0045184 141 0.013
negative regulation of transcription dna templated GO:0045892 116 0.013
inorganic cation transmembrane transport GO:0098662 202 0.013
small molecule biosynthetic process GO:0044283 124 0.013
response to hexose GO:0009746 144 0.013
rhythmic process GO:0048511 156 0.013
sex differentiation GO:0007548 113 0.013
response to mechanical stimulus GO:0009612 134 0.013
regulation of hormone levels GO:0010817 187 0.013
transmission of nerve impulse GO:0019226 42 0.013
regulation of protein phosphorylation GO:0001932 183 0.013
developmental process involved in reproduction GO:0003006 159 0.013
cell part morphogenesis GO:0032990 123 0.013
cytoskeleton organization GO:0007010 111 0.013
protein transport GO:0015031 132 0.013
negative regulation of molecular function GO:0044092 133 0.013
response to monosaccharide GO:0034284 159 0.013
embryonic pattern specification GO:0009880 1 0.013
ribonucleotide metabolic process GO:0009259 231 0.013
regulation of hydrolase activity GO:0051336 143 0.013
positive regulation of protein modification process GO:0031401 142 0.013
negative regulation of nucleic acid templated transcription GO:1903507 117 0.013
regulation of locomotion GO:0040012 148 0.013
glycosyl compound metabolic process GO:1901657 182 0.013
muscle system process GO:0003012 115 0.013
response to glucose GO:0009749 136 0.013
behavior GO:0007610 205 0.013
actin filament based process GO:0030029 86 0.013
eye morphogenesis GO:0048592 4 0.013
negative regulation of cell communication GO:0010648 158 0.013
immune system process GO:0002376 204 0.013
female pregnancy GO:0007565 122 0.013
forebrain development GO:0030900 98 0.013
action potential GO:0001508 54 0.013
response to other organism GO:0051707 220 0.012
cellular macromolecule localization GO:0070727 122 0.012
response to bacterium GO:0009617 200 0.012
monovalent inorganic cation transport GO:0015672 172 0.012
negative regulation of rna metabolic process GO:0051253 123 0.012
regulation of synaptic transmission GO:0050804 141 0.012
cell adhesion GO:0007155 110 0.012
muscle structure development GO:0061061 87 0.012
organophosphate biosynthetic process GO:0090407 143 0.012
multi multicellular organism process GO:0044706 138 0.012
negative regulation of transcription from rna polymerase ii promoter GO:0000122 75 0.012
single organism carbohydrate metabolic process GO:0044723 118 0.012
cell projection morphogenesis GO:0048858 123 0.012
gland development GO:0048732 155 0.012
regulation of protein modification process GO:0031399 194 0.012
cell morphogenesis GO:0000902 142 0.012
spermatogenesis GO:0007283 99 0.012
development of primary sexual characteristics GO:0045137 107 0.012
cell morphogenesis involved in neuron differentiation GO:0048667 106 0.012
carbohydrate metabolic process GO:0005975 130 0.012
single organism behavior GO:0044708 130 0.012
positive regulation of cellular protein metabolic process GO:0032270 167 0.012
regulation of neuron death GO:1901214 115 0.012
gastrulation GO:0007369 2 0.012
organ morphogenesis GO:0009887 75 0.012
signal transduction by phosphorylation GO:0023014 144 0.012
neuronal action potential GO:0019228 35 0.012
carbohydrate derivative biosynthetic process GO:1901137 124 0.012
reactive oxygen species biosynthetic process GO:1903409 8 0.012
reproductive system development GO:0061458 128 0.012
positive regulation of secretion GO:0051047 140 0.012
regulation of canonical wnt signaling pathway GO:0060828 4 0.012
negative regulation of protein metabolic process GO:0051248 114 0.012
ribonucleoside metabolic process GO:0009119 174 0.012
learning or memory GO:0007611 90 0.012
neuron death GO:0070997 127 0.012
single organism organelle organization GO:1902589 180 0.012
cell type specific apoptotic process GO:0097285 134 0.012
cellular protein localization GO:0034613 122 0.011
multicellular organismal signaling GO:0035637 44 0.011
calcium ion transport GO:0006816 131 0.011
positive regulation of cell motility GO:2000147 97 0.011
cytoplasmic transport GO:0016482 115 0.011
gonad development GO:0008406 104 0.011
vesicle mediated transport GO:0016192 181 0.011
heterocycle catabolic process GO:0046700 167 0.011
regulation of nucleotide metabolic process GO:0006140 117 0.011
regulation of cell motility GO:2000145 131 0.011
negative regulation of developmental process GO:0051093 125 0.011
organonitrogen compound catabolic process GO:1901565 179 0.011
sensory perception GO:0007600 101 0.011
regeneration GO:0031099 163 0.011
embryonic skeletal system morphogenesis GO:0048704 3 0.011
reactive nitrogen species metabolic process GO:2001057 1 0.011
reproductive structure development GO:0048608 128 0.011
positive regulation of protein phosphorylation GO:0001934 135 0.011
response to transition metal nanoparticle GO:1990267 122 0.011
detection of chemical stimulus involved in sensory perception of bitter taste GO:0001580 4 0.011
reactive oxygen species metabolic process GO:0072593 37 0.011
negative regulation of response to stimulus GO:0048585 155 0.011
regulation of metal ion transport GO:0010959 118 0.011
cell cycle GO:0007049 101 0.011
male gamete generation GO:0048232 99 0.011
negative regulation of rna biosynthetic process GO:1902679 118 0.011
positive regulation of cellular component movement GO:0051272 102 0.011
organonitrogen compound biosynthetic process GO:1901566 167 0.011
cellular response to peptide GO:1901653 133 0.011
regulation of homeostatic process GO:0032844 101 0.011
regulation of purine nucleotide metabolic process GO:1900542 115 0.011
anion transport GO:0006820 178 0.011
negative regulation of signaling GO:0023057 157 0.011
cardiovascular system development GO:0072358 134 0.011
regulation of anatomical structure size GO:0090066 135 0.011
appendage morphogenesis GO:0035107 4 0.011
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.010
motor neuron axon guidance GO:0008045 1 0.010
purine ribonucleoside metabolic process GO:0046128 168 0.010
multicellular organism growth GO:0035264 1 0.010
cognition GO:0050890 92 0.010
response to activity GO:0014823 73 0.010
smooth muscle cell proliferation GO:0048659 77 0.010
regulation of protein kinase activity GO:0045859 105 0.010
negative regulation of cell proliferation GO:0008285 119 0.010
response to biotic stimulus GO:0009607 226 0.010
cell growth GO:0016049 104 0.010
regulation of reactive oxygen species metabolic process GO:2000377 26 0.010
sequestering of calcium ion GO:0051208 8 0.010
mapk cascade GO:0000165 140 0.010
regulation of transferase activity GO:0051338 123 0.010
sensory perception of pain GO:0019233 73 0.010
cellular nitrogen compound catabolic process GO:0044270 163 0.010
axon development GO:0061564 96 0.010
rna localization GO:0006403 4 0.010
lipid biosynthetic process GO:0008610 128 0.010
rho protein signal transduction GO:0007266 11 0.010
inflammatory response GO:0006954 150 0.010

Reg4 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.030
nervous system disease DOID:863 0 0.030
musculoskeletal system disease DOID:17 0 0.017
sensory system disease DOID:0050155 0 0.016
central nervous system disease DOID:331 0 0.014
eye and adnexa disease DOID:1492 0 0.013
disease of metabolism DOID:0014667 0 0.013
eye disease DOID:5614 0 0.011
connective tissue disease DOID:65 0 0.010