Rattus norvegicus

44 known processes

Idh3a

isocitrate dehydrogenase 3 (NAD+) alpha

Idh3a biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
oxoacid metabolic process GO:0043436 290 0.091
coenzyme metabolic process GO:0006732 86 0.085
nucleoside phosphate metabolic process GO:0006753 283 0.074
carboxylic acid metabolic process GO:0019752 289 0.070
organophosphate metabolic process GO:0019637 370 0.059
organic acid metabolic process GO:0006082 292 0.058
regulation of apoptotic process GO:0042981 335 0.053
organic substance catabolic process GO:1901575 316 0.042
programmed cell death GO:0012501 392 0.042
nucleobase containing small molecule metabolic process GO:0055086 316 0.042
regulation of programmed cell death GO:0043067 341 0.038
response to decreased oxygen levels GO:0036293 237 0.037
transmembrane transport GO:0055085 412 0.037
carbohydrate derivative metabolic process GO:1901135 346 0.036
single organism organelle organization GO:1902589 180 0.035
apoptotic process GO:0006915 381 0.034
rna metabolic process GO:0016070 406 0.033
purine nucleoside metabolic process GO:0042278 169 0.032
cation transport GO:0006812 382 0.030
single organism biosynthetic process GO:0044711 342 0.030
ion transmembrane transport GO:0034220 365 0.028
cofactor metabolic process GO:0051186 95 0.028
organelle organization GO:0006996 266 0.027
regulation of neuron apoptotic process GO:0043523 83 0.027
purine nucleotide metabolic process GO:0006163 229 0.026
alpha amino acid metabolic process GO:1901605 71 0.026
ribose phosphate metabolic process GO:0019693 235 0.025
cellular amine metabolic process GO:0044106 38 0.025
intracellular transport GO:0046907 185 0.025
response to oxygen levels GO:0070482 265 0.025
establishment of protein localization GO:0045184 141 0.025
nucleotide metabolic process GO:0009117 279 0.025
synaptic transmission GO:0007268 235 0.025
cellular protein localization GO:0034613 122 0.024
cellular response to stress GO:0033554 269 0.024
ribonucleoside metabolic process GO:0009119 174 0.024
regulation of cellular amine metabolic process GO:0033238 8 0.024
protein transport GO:0015031 132 0.024
response to temperature stimulus GO:0009266 94 0.023
transcription dna templated GO:0006351 377 0.023
amine metabolic process GO:0009308 38 0.023
cellular macromolecule localization GO:0070727 122 0.023
response to nutrient levels GO:0031667 370 0.023
homeostatic process GO:0042592 331 0.022
response to hypoxia GO:0001666 231 0.022
metal ion transport GO:0030001 289 0.022
pyruvate metabolic process GO:0006090 27 0.022
neuron death GO:0070997 127 0.022
cellular amino acid metabolic process GO:0006520 107 0.021
g protein coupled receptor signaling pathway GO:0007186 242 0.021
generation of precursor metabolites and energy GO:0006091 62 0.021
purine ribonucleoside metabolic process GO:0046128 168 0.021
cellular homeostasis GO:0019725 252 0.021
ribonucleoside monophosphate metabolic process GO:0009161 88 0.021
purine containing compound metabolic process GO:0072521 253 0.020
oxidation reduction process GO:0055114 304 0.019
nucleoside monophosphate metabolic process GO:0009123 93 0.019
glycosyl compound metabolic process GO:1901657 182 0.019
purine ribonucleotide metabolic process GO:0009150 227 0.019
regulation of neuron death GO:1901214 115 0.019
single organism catabolic process GO:0044712 283 0.019
regulation of transcription dna templated GO:0006355 374 0.018
regulation of cell proliferation GO:0042127 359 0.018
divalent metal ion transport GO:0070838 132 0.018
ribose phosphate biosynthetic process GO:0046390 87 0.018
regulation of cellular amino acid metabolic process GO:0006521 2 0.018
purine containing compound biosynthetic process GO:0072522 85 0.018
negative regulation of apoptotic process GO:0043066 181 0.017
positive regulation of molecular function GO:0044093 230 0.017
purine nucleoside monophosphate metabolic process GO:0009126 84 0.017
response to ethanol GO:0045471 162 0.017
proteolysis GO:0006508 175 0.017
catabolic process GO:0009056 351 0.017
small molecule biosynthetic process GO:0044283 124 0.017
purine ribonucleoside monophosphate metabolic process GO:0009167 84 0.017
behavior GO:0007610 205 0.017
nucleobase containing compound catabolic process GO:0034655 152 0.017
anatomical structure morphogenesis GO:0009653 298 0.017
cellular ketone metabolic process GO:0042180 51 0.017
response to extracellular stimulus GO:0009991 380 0.016
negative regulation of programmed cell death GO:0043069 183 0.016
response to acid chemical GO:0001101 222 0.016
regulation of rna biosynthetic process GO:2001141 381 0.016
negative regulation of cell death GO:0060548 229 0.016
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.016
response to glucose GO:0009749 136 0.016
head development GO:0060322 247 0.016
central nervous system development GO:0007417 311 0.016
response to monosaccharide GO:0034284 159 0.016
intracellular signal transduction GO:0035556 314 0.016
macromolecular complex subunit organization GO:0043933 339 0.016
response to carbohydrate GO:0009743 183 0.015
purine nucleoside triphosphate metabolic process GO:0009144 141 0.015
cell type specific apoptotic process GO:0097285 134 0.015
cofactor biosynthetic process GO:0051188 28 0.015
nucleic acid templated transcription GO:0097659 379 0.015
cellular response to oxygen containing compound GO:1901701 386 0.015
positive regulation of cell proliferation GO:0008284 249 0.015
organic acid biosynthetic process GO:0016053 83 0.015
regulation of multicellular organismal development GO:2000026 376 0.015
negative regulation of metabolic process GO:0009892 331 0.015
response to alkaloid GO:0043279 132 0.015
ribonucleotide biosynthetic process GO:0009260 85 0.015
secretion GO:0046903 307 0.015
carbohydrate derivative biosynthetic process GO:1901137 124 0.015
regulation of cellular protein metabolic process GO:0032268 267 0.014
nucleotide biosynthetic process GO:0009165 98 0.014
nucleoside phosphate biosynthetic process GO:1901293 102 0.014
reproduction GO:0000003 245 0.014
oxidoreduction coenzyme metabolic process GO:0006733 31 0.014
nucleoside metabolic process GO:0009116 179 0.014
cation transmembrane transport GO:0098655 263 0.014
regulation of protein metabolic process GO:0051246 289 0.014
growth GO:0040007 165 0.014
chemical homeostasis GO:0048878 292 0.013
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.013
regulation of catalytic activity GO:0050790 304 0.013
positive regulation of cellular biosynthetic process GO:0031328 295 0.013
regulation of molecular function GO:0065009 398 0.013
regulation of nervous system development GO:0051960 264 0.013
positive regulation of signaling GO:0023056 270 0.013
purine nucleotide biosynthetic process GO:0006164 83 0.013
gastrulation GO:0007369 2 0.013
regulation of cellular ketone metabolic process GO:0010565 27 0.013
regulation of membrane potential GO:0042391 110 0.013
response to hexose GO:0009746 144 0.013
calcium ion transport GO:0006816 131 0.013
response to nutrient GO:0007584 248 0.013
regulation of metal ion transport GO:0010959 118 0.013
positive regulation of cellular amine metabolic process GO:0033240 3 0.013
ribonucleotide metabolic process GO:0009259 231 0.013
cellular amino acid biosynthetic process GO:0008652 32 0.012
single organism intracellular transport GO:1902582 166 0.012
divalent inorganic cation transport GO:0072511 134 0.012
energy derivation by oxidation of organic compounds GO:0015980 46 0.012
negative regulation of macromolecule metabolic process GO:0010605 260 0.012
carbohydrate metabolic process GO:0005975 130 0.012
anterior posterior pattern specification GO:0009952 1 0.012
organophosphate biosynthetic process GO:0090407 143 0.012
positive regulation of biosynthetic process GO:0009891 319 0.012
regulation of neurogenesis GO:0050767 247 0.012
positive regulation of cell death GO:0010942 184 0.012
sulfur compound metabolic process GO:0006790 70 0.012
regulation of rna metabolic process GO:0051252 391 0.012
carbohydrate derivative catabolic process GO:1901136 147 0.012
dna metabolic process GO:0006259 96 0.012
positive regulation of apoptotic process GO:0043065 154 0.012
multicellular organismal reproductive process GO:0048609 233 0.012
anion transport GO:0006820 178 0.012
regulation of signal transduction GO:0009966 318 0.012
brain development GO:0007420 247 0.012
single organism cellular localization GO:1902580 102 0.012
ribonucleoside triphosphate metabolic process GO:0009199 141 0.012
carboxylic acid biosynthetic process GO:0046394 83 0.012
rna biosynthetic process GO:0032774 380 0.012
response to corticosteroid GO:0031960 235 0.012
pyridine containing compound metabolic process GO:0072524 32 0.011
organonitrogen compound catabolic process GO:1901565 179 0.011
inorganic cation transmembrane transport GO:0098662 202 0.011
positive regulation of transport GO:0051050 245 0.011
purine ribonucleotide catabolic process GO:0009154 136 0.011
cellular response to lipid GO:0071396 201 0.011
reproductive process GO:0022414 372 0.011
regulation of growth GO:0040008 105 0.011
cellular chemical homeostasis GO:0055082 247 0.011
blood circulation GO:0008015 183 0.011
dicarboxylic acid catabolic process GO:0043649 1 0.011
protein oligomerization GO:0051259 191 0.011
response to metal ion GO:0010038 253 0.011
glycosyl compound catabolic process GO:1901658 126 0.011
nitrogen compound transport GO:0071705 229 0.011
response to inorganic substance GO:0010035 377 0.011
cell cell signaling GO:0007267 335 0.011
cellular modified amino acid metabolic process GO:0006575 61 0.011
intracellular protein transport GO:0006886 79 0.011
cellular component assembly GO:0022607 360 0.011
response to oxidative stress GO:0006979 186 0.011
multicellular organism reproduction GO:0032504 233 0.011
regulation of cellular component organization GO:0051128 368 0.011
cellular catabolic process GO:0044248 295 0.011
response to toxic substance GO:0009636 133 0.011
neuron apoptotic process GO:0051402 88 0.011
cell cycle checkpoint GO:0000075 2 0.011
cellular response to hormone stimulus GO:0032870 247 0.010
protein localization GO:0008104 191 0.010
response to ketone GO:1901654 182 0.010
nucleoside triphosphate metabolic process GO:0009141 144 0.010
positive regulation of multicellular organismal process GO:0051240 387 0.010
positive regulation of developmental process GO:0051094 283 0.010
macromolecular complex assembly GO:0065003 273 0.010
negative regulation of mitotic cell cycle phase transition GO:1901991 3 0.010
multi organism reproductive process GO:0044703 262 0.010

Idh3a disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.048
nervous system disease DOID:863 0 0.048
central nervous system disease DOID:331 0 0.023
musculoskeletal system disease DOID:17 0 0.015