Rattus norvegicus

48 known processes

Tle3

transducin-like enhancer of split 3 (E(sp1) homolog, Drosophila)

(Aliases: Esp3)

Tle3 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
transcription dna templated GO:0006351 377 0.099
rna metabolic process GO:0016070 406 0.098
regulation of rna biosynthetic process GO:2001141 381 0.096
regulation of rna metabolic process GO:0051252 391 0.065
positive regulation of multicellular organismal process GO:0051240 387 0.064
regulation of multicellular organismal development GO:2000026 376 0.061
Worm
regulation of transcription dna templated GO:0006355 374 0.059
cellular response to endogenous stimulus GO:0071495 377 0.055
cellular response to oxygen containing compound GO:1901701 386 0.054
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.053
rna biosynthetic process GO:0032774 380 0.049
neuron differentiation GO:0030182 368 0.049
Worm Fly
transcription from rna polymerase ii promoter GO:0006366 252 0.048
Fly
regulation of nucleic acid templated transcription GO:1903506 380 0.048
reproductive process GO:0022414 372 0.047
Worm
nucleic acid templated transcription GO:0097659 379 0.047
locomotion GO:0040011 237 0.046
Worm
organic acid metabolic process GO:0006082 292 0.045
Zebrafish
negative regulation of metabolic process GO:0009892 331 0.044
Fly
response to peptide hormone GO:0043434 278 0.044
carboxylic acid metabolic process GO:0019752 289 0.044
Zebrafish
negative regulation of biosynthetic process GO:0009890 168 0.043
Fly
positive regulation of biosynthetic process GO:0009891 319 0.043
response to peptide GO:1901652 292 0.042
regulation of signal transduction GO:0009966 318 0.042
Fly
central nervous system development GO:0007417 311 0.041
neuron development GO:0048666 286 0.041
Worm Fly
organic substance catabolic process GO:1901575 316 0.040
catabolic process GO:0009056 351 0.039
cell projection organization GO:0030030 302 0.038
Worm Fly
intracellular signal transduction GO:0035556 314 0.038
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.037
cellular response to nitrogen compound GO:1901699 210 0.036
regulation of nervous system development GO:0051960 264 0.035
Worm
response to cytokine GO:0034097 215 0.035
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.035
Fly
positive regulation of developmental process GO:0051094 283 0.034
response to acid chemical GO:0001101 222 0.034
lipid metabolic process GO:0006629 283 0.034
Zebrafish
negative regulation of cellular metabolic process GO:0031324 281 0.033
Fly
positive regulation of cellular biosynthetic process GO:0031328 295 0.033
regulation of cell development GO:0060284 263 0.033
Worm
negative regulation of macromolecule metabolic process GO:0010605 260 0.033
Fly
protein complex subunit organization GO:0071822 302 0.032
Fly
neuron projection development GO:0031175 273 0.032
Worm Fly
macromolecular complex subunit organization GO:0043933 339 0.031
Fly
regulation of proteasomal protein catabolic process GO:0061136 4 0.030
regulation of catalytic activity GO:0050790 304 0.030
regulation of neurogenesis GO:0050767 247 0.030
Worm
cellular ketone metabolic process GO:0042180 51 0.030
Zebrafish
response to insulin GO:0032868 133 0.030
cellular amino acid metabolic process GO:0006520 107 0.030
oxoacid metabolic process GO:0043436 290 0.030
Zebrafish
regulation of cellular amine metabolic process GO:0033238 8 0.029
positive regulation of cell proliferation GO:0008284 249 0.029
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.029
positive regulation of response to stimulus GO:0048584 285 0.029
multi organism reproductive process GO:0044703 262 0.029
Worm
head development GO:0060322 247 0.029
anatomical structure morphogenesis GO:0009653 298 0.029
Worm Fly
negative regulation of cellular biosynthetic process GO:0031327 161 0.028
Fly
positive regulation of rna biosynthetic process GO:1902680 197 0.028
response to metal ion GO:0010038 253 0.028
negative regulation of transcription dna templated GO:0045892 116 0.028
Fly
regulation of phosphorus metabolic process GO:0051174 349 0.028
transmembrane transport GO:0055085 412 0.027
response to wounding GO:0009611 254 0.027
chemical homeostasis GO:0048878 292 0.027
brain development GO:0007420 247 0.027
regulation of cell differentiation GO:0045595 320 0.027
Worm
cellular catabolic process GO:0044248 295 0.027
organophosphate metabolic process GO:0019637 370 0.027
carbohydrate derivative metabolic process GO:1901135 346 0.027
response to inorganic substance GO:0010035 377 0.027
reproduction GO:0000003 245 0.027
Worm
regulation of molecular function GO:0065009 398 0.027
ion transmembrane transport GO:0034220 365 0.026
response to oxygen levels GO:0070482 265 0.026
regulation of cellular ketone metabolic process GO:0010565 27 0.026
Zebrafish
response to external biotic stimulus GO:0043207 221 0.026
response to extracellular stimulus GO:0009991 380 0.026
negative regulation of multicellular organismal process GO:0051241 203 0.026
cell motility GO:0048870 202 0.025
positive regulation of gene expression GO:0010628 244 0.025
positive regulation of cell differentiation GO:0045597 217 0.025
positive regulation of molecular function GO:0044093 230 0.025
cellular component movement GO:0006928 248 0.025
regulation of cellular amino acid metabolic process GO:0006521 2 0.025
amine metabolic process GO:0009308 38 0.025
cellular response to organonitrogen compound GO:0071417 197 0.025
cation transport GO:0006812 382 0.024
cellular response to growth factor stimulus GO:0071363 162 0.024
organelle organization GO:0006996 266 0.024
Fly
regulation of protein metabolic process GO:0051246 289 0.024
defense response GO:0006952 194 0.024
cellular component biogenesis GO:0044085 368 0.024
localization of cell GO:0051674 202 0.024
protein complex biogenesis GO:0070271 263 0.024
oxidation reduction process GO:0055114 304 0.023
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.023
Fly
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.023
Fly
cellular response to stress GO:0033554 269 0.023
protein phosphorylation GO:0006468 345 0.023
cellular response to organic cyclic compound GO:0071407 202 0.023
positive regulation of transcription dna templated GO:0045893 197 0.023
regulation of apoptotic process GO:0042981 335 0.023
tissue development GO:0009888 252 0.023
cellular amine metabolic process GO:0044106 38 0.023
regulation of cellular protein metabolic process GO:0032268 267 0.023
cellular response to lipid GO:0071396 201 0.022
single organism catabolic process GO:0044712 283 0.022
regulation of cell proliferation GO:0042127 359 0.022
macromolecule localization GO:0033036 252 0.022
cell morphogenesis involved in differentiation GO:0000904 119 0.022
Worm Fly
cell cell signaling GO:0007267 335 0.021
Worm Fly
response to nutrient levels GO:0031667 370 0.021
response to growth factor GO:0070848 189 0.021
small gtpase mediated signal transduction GO:0007264 36 0.021
ras protein signal transduction GO:0007265 29 0.021
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.020
Fly
protein transport GO:0015031 132 0.020
cellular response to cytokine stimulus GO:0071345 127 0.020
homeostatic process GO:0042592 331 0.020
single organism reproductive process GO:0044702 297 0.020
Worm
cellular lipid metabolic process GO:0044255 208 0.020
Zebrafish
protein complex assembly GO:0006461 263 0.020
regulation of neuron projection development GO:0010975 161 0.020
Worm
response to biotic stimulus GO:0009607 226 0.019
response to oxidative stress GO:0006979 186 0.019
negative regulation of rna biosynthetic process GO:1902679 118 0.019
Fly
nitrogen compound transport GO:0071705 229 0.019
regulation of cellular catabolic process GO:0031329 101 0.019
multicellular organismal reproductive process GO:0048609 233 0.019
Worm
regulation of programmed cell death GO:0043067 341 0.019
negative regulation of cell differentiation GO:0045596 99 0.019
multicellular organism reproduction GO:0032504 233 0.019
Worm
sexual reproduction GO:0019953 148 0.019
Worm
regulation of cellular component movement GO:0051270 150 0.019
response to bacterium GO:0009617 200 0.019
neuron projection morphogenesis GO:0048812 122 0.018
Worm Fly
positive regulation of signaling GO:0023056 270 0.018
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.018
apoptotic process GO:0006915 381 0.018
macromolecular complex assembly GO:0065003 273 0.018
establishment of protein localization GO:0045184 141 0.018
tube development GO:0035295 89 0.018
nucleoside phosphate metabolic process GO:0006753 283 0.018
cellular response to peptide hormone stimulus GO:0071375 120 0.018
response to molecule of bacterial origin GO:0002237 194 0.018
regulation of cellular component organization GO:0051128 368 0.018
Worm
regulation of phosphate metabolic process GO:0019220 349 0.018
nucleobase containing small molecule metabolic process GO:0055086 316 0.018
single organism organelle organization GO:1902589 180 0.018
Fly
ribose phosphate metabolic process GO:0019693 235 0.018
b cell differentiation GO:0030183 2 0.018
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.018
Fly
inflammatory response GO:0006954 150 0.018
positive regulation of cell development GO:0010720 176 0.017
protein oligomerization GO:0051259 191 0.017
aging GO:0007568 241 0.017
positive regulation of nervous system development GO:0051962 178 0.017
response to glucose GO:0009749 136 0.017
positive regulation of apoptotic process GO:0043065 154 0.017
single organism biosynthetic process GO:0044711 342 0.017
Zebrafish
regulation of cell projection organization GO:0031344 175 0.017
Worm
regulation of intracellular signal transduction GO:1902531 218 0.017
cell part morphogenesis GO:0032990 123 0.017
Worm Fly
negative regulation of gene expression GO:0010629 199 0.017
Fly
secretion GO:0046903 307 0.017
programmed cell death GO:0012501 392 0.016
positive regulation of nucleic acid templated transcription GO:1903508 197 0.016
response to other organism GO:0051707 220 0.016
ion homeostasis GO:0050801 212 0.016
monocarboxylic acid metabolic process GO:0032787 152 0.016
Zebrafish
positive regulation of neurogenesis GO:0050769 165 0.016
growth GO:0040007 165 0.016
heterocycle catabolic process GO:0046700 167 0.016
cellular divalent inorganic cation homeostasis GO:0072503 162 0.016
lipid biosynthetic process GO:0008610 128 0.016
Zebrafish
positive regulation of catalytic activity GO:0043085 184 0.016
negative regulation of developmental process GO:0051093 125 0.016
negative regulation of nucleic acid templated transcription GO:1903507 117 0.016
Fly
protein localization GO:0008104 191 0.016
eye morphogenesis GO:0048592 4 0.015
spindle organization GO:0007051 2 0.015
proteolysis GO:0006508 175 0.015
small molecule biosynthetic process GO:0044283 124 0.015
Zebrafish
response to corticosteroid GO:0031960 235 0.015
regulation of immune system process GO:0002682 123 0.015
gland development GO:0048732 155 0.015
cellular nitrogen compound catabolic process GO:0044270 163 0.015
negative regulation of cell death GO:0060548 229 0.015
nucleoside metabolic process GO:0009116 179 0.015
enzyme linked receptor protein signaling pathway GO:0007167 116 0.015
cellular component assembly GO:0022607 360 0.015
secretion by cell GO:0032940 248 0.015
single organism intracellular transport GO:1902582 166 0.015
positive regulation of phosphorus metabolic process GO:0010562 262 0.015
positive regulation of rna metabolic process GO:0051254 203 0.015
positive regulation of mesenchymal cell proliferation GO:0002053 4 0.015
cell adhesion GO:0007155 110 0.015
regulation of cell motility GO:2000145 131 0.015
regulation of system process GO:0044057 208 0.015
positive regulation of cellular amine metabolic process GO:0033240 3 0.015
cation homeostasis GO:0055080 195 0.014
cellular response to hormone stimulus GO:0032870 247 0.014
positive regulation of cell communication GO:0010647 271 0.014
cellular response to peptide GO:1901653 133 0.014
response to radiation GO:0009314 137 0.014
multi multicellular organism process GO:0044706 138 0.014
anion transport GO:0006820 178 0.014
cell projection morphogenesis GO:0048858 123 0.014
Worm Fly
purine ribonucleoside metabolic process GO:0046128 168 0.014
negative regulation of innate immune response GO:0045824 4 0.014
dendrite development GO:0016358 72 0.014
Fly
regulation of synaptic transmission GO:0050804 141 0.014
positive regulation of programmed cell death GO:0043068 157 0.014
response to estrogen GO:0043627 232 0.014
calcium ion transport GO:0006816 131 0.014
behavior GO:0007610 205 0.014
carbohydrate derivative biosynthetic process GO:1901137 124 0.014
gastrulation GO:0007369 2 0.014
glycosyl compound metabolic process GO:1901657 182 0.014
regulation of neuron differentiation GO:0045664 208 0.014
Worm
adult locomotory behavior GO:0008344 4 0.014
response to decreased oxygen levels GO:0036293 237 0.014
multicellular organism growth GO:0035264 1 0.014
regulation of catabolic process GO:0009894 113 0.013
negative regulation of transcription from rna polymerase ii promoter GO:0000122 75 0.013
Fly
organic cyclic compound catabolic process GO:1901361 175 0.013
cytokine biosynthetic process GO:0042089 3 0.013
rhythmic process GO:0048511 156 0.013
regulation of neuron death GO:1901214 115 0.013
regeneration GO:0031099 163 0.013
cellular chemical homeostasis GO:0055082 247 0.013
cellular homeostasis GO:0019725 252 0.013
negative regulation of molecular function GO:0044092 133 0.013
response to carbohydrate GO:0009743 183 0.013
regulation of response to stress GO:0080134 126 0.013
purine ribonucleotide metabolic process GO:0009150 227 0.013
response to hypoxia GO:0001666 231 0.013
cellular cation homeostasis GO:0030003 180 0.013
ribonucleotide metabolic process GO:0009259 231 0.013
cytoskeleton organization GO:0007010 111 0.013
Fly
response to lipopolysaccharide GO:0032496 191 0.013
carbohydrate metabolic process GO:0005975 130 0.013
purine containing compound metabolic process GO:0072521 253 0.013
positive regulation of protein metabolic process GO:0051247 178 0.013
cellular protein localization GO:0034613 122 0.013
negative regulation of protein metabolic process GO:0051248 114 0.013
regulation of hydrolase activity GO:0051336 143 0.013
intracellular transport GO:0046907 185 0.013
establishment of tissue polarity GO:0007164 2 0.013
cellular response to insulin stimulus GO:0032869 81 0.013
regulation of locomotion GO:0040012 148 0.013
salivary gland development GO:0007431 3 0.013
limb morphogenesis GO:0035108 4 0.013
immune system development GO:0002520 41 0.013
Zebrafish
positive regulation of cell death GO:0010942 184 0.013
forebrain development GO:0030900 98 0.013
axon development GO:0061564 96 0.013
Worm
nucleotide metabolic process GO:0009117 279 0.013
regulation of growth GO:0040008 105 0.013
synaptic transmission GO:0007268 235 0.012
Worm
negative regulation of rna metabolic process GO:0051253 123 0.012
Fly
intracellular protein transport GO:0006886 79 0.012
ribonucleoside catabolic process GO:0042454 126 0.012
regulation of secretion GO:0051046 224 0.012
circulatory system development GO:0072359 134 0.012
regulation of body fluid levels GO:0050878 90 0.012
positive regulation of transport GO:0051050 245 0.012
positive regulation of neuron differentiation GO:0045666 126 0.012
response to hexose GO:0009746 144 0.012
divalent inorganic cation homeostasis GO:0072507 165 0.012
negative regulation of neurogenesis GO:0050768 78 0.012
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.012
axis specification GO:0009798 4 0.012
inorganic ion transmembrane transport GO:0098660 229 0.012
cell migration GO:0016477 197 0.012
cellular response to acid chemical GO:0071229 75 0.012
regulation of phosphorylation GO:0042325 248 0.012
cellular ion homeostasis GO:0006873 184 0.012
regulation of cellular localization GO:0060341 263 0.012
negative regulation of nervous system development GO:0051961 79 0.012
cellular macromolecule localization GO:0070727 122 0.012
calcium ion homeostasis GO:0055074 162 0.012
peptidyl tyrosine phosphorylation GO:0018108 72 0.012
regulation of cytokine production GO:0001817 56 0.012
metal ion transport GO:0030001 289 0.012
regulation of secretion by cell GO:1903530 208 0.012
negative regulation of apoptotic process GO:0043066 181 0.012
dephosphorylation GO:0016311 98 0.012
aromatic compound catabolic process GO:0019439 168 0.012
embryonic pattern specification GO:0009880 1 0.012
insulin like growth factor receptor signaling pathway GO:0048009 3 0.011
sex differentiation GO:0007548 113 0.011
Worm
ribonucleoside metabolic process GO:0009119 174 0.011
nucleoside triphosphate metabolic process GO:0009141 144 0.011
response to estradiol GO:0032355 164 0.011
positive regulation of cellular component movement GO:0051272 102 0.011
carbohydrate derivative catabolic process GO:1901136 147 0.011
response to monosaccharide GO:0034284 159 0.011
response to tumor necrosis factor GO:0034612 56 0.011
regulation of purine nucleotide metabolic process GO:1900542 115 0.011
organonitrogen compound catabolic process GO:1901565 179 0.011
immune system process GO:0002376 204 0.011
Zebrafish
urogenital system development GO:0001655 78 0.011
peptidyl amino acid modification GO:0018193 126 0.011
response to nutrient GO:0007584 248 0.011
purine nucleoside metabolic process GO:0042278 169 0.011
gamete generation GO:0007276 124 0.011
Worm
positive regulation of cellular component organization GO:0051130 200 0.011
cation transmembrane transport GO:0098655 263 0.011
negative regulation of immune system process GO:0002683 39 0.011
metal ion homeostasis GO:0055065 186 0.011
cell morphogenesis GO:0000902 142 0.011
Worm Fly
reproductive system development GO:0061458 128 0.011
Worm
negative regulation of response to stimulus GO:0048585 155 0.011
Fly
protein targeting GO:0006605 61 0.011
regulation of reactive oxygen species biosynthetic process GO:1903426 5 0.011
positive regulation of signal transduction GO:0009967 175 0.011
negative regulation of catalytic activity GO:0043086 103 0.011
positive regulation of phosphate metabolic process GO:0045937 262 0.011
circulatory system process GO:0003013 183 0.011
regulation of protein phosphorylation GO:0001932 183 0.011
anterior posterior pattern specification GO:0009952 1 0.011
organic acid transport GO:0015849 116 0.010
cellular response to external stimulus GO:0071496 118 0.010
cardiovascular system development GO:0072358 134 0.010
purine ribonucleoside triphosphate metabolic process GO:0009205 140 0.010
regulation of anatomical structure size GO:0090066 135 0.010
purine nucleotide metabolic process GO:0006163 229 0.010
immune response GO:0006955 104 0.010
camera type eye morphogenesis GO:0048593 2 0.010
negative regulation of phosphate metabolic process GO:0045936 80 0.010
regulation of anatomical structure morphogenesis GO:0022603 141 0.010
Worm
male gamete generation GO:0048232 99 0.010
regulation of immunoglobulin secretion GO:0051023 1 0.010
cell activation GO:0001775 97 0.010
divalent metal ion transport GO:0070838 132 0.010
positive regulation of cell projection organization GO:0031346 111 0.010
regulation of ion transport GO:0043269 245 0.010
development of primary sexual characteristics GO:0045137 107 0.010
Worm
carboxylic acid transport GO:0046942 115 0.010
actin cytoskeleton organization GO:0030036 73 0.010
Fly
cytokine production GO:0001816 61 0.010
regulation of cell migration GO:0030334 128 0.010

Tle3 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.017
nervous system disease DOID:863 0 0.017