Rattus norvegicus

0 known processes

Mlph

melanophilin

Mlph biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
regulation of ion transport GO:0043269 245 0.177
metal ion transport GO:0030001 289 0.082
transmembrane transport GO:0055085 412 0.076
ion transmembrane transport GO:0034220 365 0.076
cation transport GO:0006812 382 0.073
cation transmembrane transport GO:0098655 263 0.069
chemical homeostasis GO:0048878 292 0.062
cellular homeostasis GO:0019725 252 0.050
intracellular signal transduction GO:0035556 314 0.048
reproduction GO:0000003 245 0.048
regulation of phosphorus metabolic process GO:0051174 349 0.047
regulation of molecular function GO:0065009 398 0.047
response to acid chemical GO:0001101 222 0.046
programmed cell death GO:0012501 392 0.042
response to metal ion GO:0010038 253 0.042
response to inorganic substance GO:0010035 377 0.042
synaptic transmission GO:0007268 235 0.041
reproductive process GO:0022414 372 0.041
positive regulation of ion transport GO:0043270 94 0.038
ion homeostasis GO:0050801 212 0.037
monovalent inorganic cation transport GO:0015672 172 0.034
single organism reproductive process GO:0044702 297 0.033
cellular metal ion homeostasis GO:0006875 172 0.033
homeostatic process GO:0042592 331 0.033
anion transport GO:0006820 178 0.033
regulation of phosphate metabolic process GO:0019220 349 0.032
cellular response to acid chemical GO:0071229 75 0.031
metal ion homeostasis GO:0055065 186 0.030
organic acid biosynthetic process GO:0016053 83 0.030
cellular component biogenesis GO:0044085 368 0.029
positive regulation of biosynthetic process GO:0009891 319 0.029
protein complex biogenesis GO:0070271 263 0.028
negative regulation of cell death GO:0060548 229 0.028
divalent metal ion transport GO:0070838 132 0.027
cellular cation homeostasis GO:0030003 180 0.027
cellular response to oxygen containing compound GO:1901701 386 0.027
regulation of cellular protein metabolic process GO:0032268 267 0.027
cellular component assembly GO:0022607 360 0.027
divalent inorganic cation transport GO:0072511 134 0.026
response to extracellular stimulus GO:0009991 380 0.026
protein complex assembly GO:0006461 263 0.026
protein phosphorylation GO:0006468 345 0.026
amine metabolic process GO:0009308 38 0.026
positive regulation of cellular biosynthetic process GO:0031328 295 0.026
regulation of metal ion transport GO:0010959 118 0.026
regulation of catalytic activity GO:0050790 304 0.026
protein oligomerization GO:0051259 191 0.026
cellular lipid metabolic process GO:0044255 208 0.025
negative regulation of response to stimulus GO:0048585 155 0.025
single organism biosynthetic process GO:0044711 342 0.025
nucleobase containing small molecule metabolic process GO:0055086 316 0.025
regulation of cell proliferation GO:0042127 359 0.024
single organism intracellular transport GO:1902582 166 0.024
regulation of ion transmembrane transport GO:0034765 121 0.024
organophosphate metabolic process GO:0019637 370 0.024
secretion GO:0046903 307 0.024
Rat
multi organism reproductive process GO:0044703 262 0.024
tongue morphogenesis GO:0043587 3 0.024
ribose phosphate metabolic process GO:0019693 235 0.024
calcium ion homeostasis GO:0055074 162 0.024
cellular ion homeostasis GO:0006873 184 0.024
negative regulation of metabolic process GO:0009892 331 0.023
cellular chemical homeostasis GO:0055082 247 0.023
regulation of transmembrane transport GO:0034762 122 0.022
multicellular organism reproduction GO:0032504 233 0.022
divalent inorganic cation homeostasis GO:0072507 165 0.022
negative regulation of cell communication GO:0010648 158 0.022
inorganic ion transmembrane transport GO:0098660 229 0.022
chromosome segregation GO:0007059 2 0.021
cellular divalent inorganic cation homeostasis GO:0072503 162 0.021
positive regulation of response to stimulus GO:0048584 285 0.021
macromolecular complex subunit organization GO:0043933 339 0.021
cell cycle GO:0007049 101 0.021
lipid metabolic process GO:0006629 283 0.021
protein localization GO:0008104 191 0.020
regulation of multicellular organismal development GO:2000026 376 0.020
cation homeostasis GO:0055080 195 0.020
positive regulation of protein metabolic process GO:0051247 178 0.020
apoptotic process GO:0006915 381 0.019
macromolecular complex assembly GO:0065003 273 0.019
response to wounding GO:0009611 254 0.019
regulation of cellular amino acid metabolic process GO:0006521 2 0.018
cytosolic calcium ion homeostasis GO:0051480 140 0.018
multicellular organismal reproductive process GO:0048609 233 0.018
negative regulation of secretion GO:0051048 82 0.017
regulation of cellular ketone metabolic process GO:0010565 27 0.017
regulation of cellular component organization GO:0051128 368 0.017
organic acid transport GO:0015849 116 0.017
intracellular transport GO:0046907 185 0.017
negative regulation of signaling GO:0023057 157 0.017
protein complex subunit organization GO:0071822 302 0.017
nitrogen compound transport GO:0071705 229 0.016
Rat
regulation of cellular amine metabolic process GO:0033238 8 0.016
central nervous system development GO:0007417 311 0.016
cellular response to endogenous stimulus GO:0071495 377 0.016
inorganic cation transmembrane transport GO:0098662 202 0.016
wound healing GO:0042060 122 0.016
organic anion transport GO:0015711 132 0.016
cellular amine metabolic process GO:0044106 38 0.016
negative regulation of transport GO:0051051 136 0.016
regulation of apoptotic process GO:0042981 335 0.016
carboxylic acid metabolic process GO:0019752 289 0.016
positive regulation of gene expression GO:0010628 244 0.016
regulation of protein phosphorylation GO:0001932 183 0.015
cellular calcium ion homeostasis GO:0006874 160 0.015
regulation of protein metabolic process GO:0051246 289 0.015
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.015
purine nucleotide metabolic process GO:0006163 229 0.014
sexual reproduction GO:0019953 148 0.014
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.014
negative regulation of programmed cell death GO:0043069 183 0.014
regulation of canonical wnt signaling pathway GO:0060828 4 0.014
regulation of transporter activity GO:0032409 50 0.014
negative regulation of signal transduction GO:0009968 83 0.014
meiotic cell cycle process GO:1903046 3 0.014
memory GO:0007613 54 0.014
macromolecule localization GO:0033036 252 0.014
response to bacterium GO:0009617 200 0.014
cellular response to stress GO:0033554 269 0.014
multi multicellular organism process GO:0044706 138 0.014
aging GO:0007568 241 0.014
sodium ion transport GO:0006814 82 0.014
response to molecule of bacterial origin GO:0002237 194 0.014
regulation of protein kinase activity GO:0045859 105 0.014
anterior posterior pattern specification GO:0009952 1 0.014
alcohol metabolic process GO:0006066 77 0.013
g protein coupled receptor signaling pathway GO:0007186 242 0.013
nucleotide metabolic process GO:0009117 279 0.013
heart morphogenesis GO:0003007 3 0.013
cell cell signaling GO:0007267 335 0.013
Rat
lipid biosynthetic process GO:0008610 128 0.013
positive regulation of cellular component organization GO:0051130 200 0.013
oxoacid metabolic process GO:0043436 290 0.013
regulation of body fluid levels GO:0050878 90 0.013
ras protein signal transduction GO:0007265 29 0.013
anion transmembrane transport GO:0098656 77 0.013
organelle organization GO:0006996 266 0.013
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.013
positive regulation of transcription dna templated GO:0045893 197 0.013
regulation of nucleic acid templated transcription GO:1903506 380 0.013
defense response GO:0006952 194 0.013
positive regulation of cell communication GO:0010647 271 0.013
Rat
small gtpase mediated signal transduction GO:0007264 36 0.013
telencephalon development GO:0021537 62 0.013
regulation of ion transmembrane transporter activity GO:0032412 48 0.013
cell projection organization GO:0030030 302 0.013
negative regulation of cellular metabolic process GO:0031324 281 0.013
positive regulation of cellular amine metabolic process GO:0033240 3 0.013
rhythmic process GO:0048511 156 0.013
negative regulation of multicellular organismal process GO:0051241 203 0.013
negative regulation of molecular function GO:0044092 133 0.012
regulation of transmembrane transporter activity GO:0022898 49 0.012
regulation of establishment of planar polarity GO:0090175 2 0.012
carbohydrate derivative metabolic process GO:1901135 346 0.012
carboxylic acid biosynthetic process GO:0046394 83 0.012
regulation of calcium ion transport GO:0051924 77 0.012
morphogenesis of a polarized epithelium GO:0001738 1 0.012
vesicle mediated transport GO:0016192 181 0.012
isoprenoid metabolic process GO:0006720 45 0.012
regulation of cell projection organization GO:0031344 175 0.012
mesoderm development GO:0007498 2 0.012
neuron differentiation GO:0030182 368 0.012
behavior GO:0007610 205 0.012
positive regulation of cytosolic calcium ion concentration GO:0007204 122 0.012
non canonical wnt signaling pathway GO:0035567 3 0.012
establishment of tissue polarity GO:0007164 2 0.012
regulation of membrane potential GO:0042391 110 0.012
regulation of signal transduction GO:0009966 318 0.012
organic cyclic compound catabolic process GO:1901361 175 0.011
response to transition metal nanoparticle GO:1990267 122 0.011
acid secretion GO:0046717 48 0.011
transmission of nerve impulse GO:0019226 42 0.011
rna biosynthetic process GO:0032774 380 0.011
cognition GO:0050890 92 0.011
positive regulation of phosphorylation GO:0042327 177 0.011
cellular macromolecule localization GO:0070727 122 0.011
positive regulation of phosphate metabolic process GO:0045937 262 0.011
circadian rhythm GO:0007623 88 0.011
regulation of hormone levels GO:0010817 187 0.011
Rat
regulation of purine nucleotide metabolic process GO:1900542 115 0.011
positive regulation of cell proliferation GO:0008284 249 0.011
regulation of synaptic transmission GO:0050804 141 0.011
response to nutrient levels GO:0031667 370 0.011
purine ribonucleotide metabolic process GO:0009150 227 0.011
regulation of hydrolase activity GO:0051336 143 0.011
regulation of anion transport GO:0044070 43 0.011
multicellular organismal signaling GO:0035637 44 0.011
positive regulation of molecular function GO:0044093 230 0.011
cell junction maintenance GO:0034331 1 0.011
response to nutrient GO:0007584 248 0.011
nucleic acid templated transcription GO:0097659 379 0.011
negative regulation of macromolecule metabolic process GO:0010605 260 0.011
guanosine containing compound catabolic process GO:1901069 71 0.011
neuron projection development GO:0031175 273 0.011
positive regulation of catalytic activity GO:0043085 184 0.010
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.010
negative regulation of gene expression GO:0010629 199 0.010
insulin like growth factor receptor signaling pathway GO:0048009 3 0.010
hormone metabolic process GO:0042445 69 0.010
organic acid metabolic process GO:0006082 292 0.010
single organism behavior GO:0044708 130 0.010
cytoplasmic transport GO:0016482 115 0.010
gamete generation GO:0007276 124 0.010
positive regulation of protein phosphorylation GO:0001934 135 0.010
catabolic process GO:0009056 351 0.010
cell part morphogenesis GO:0032990 123 0.010
regulation of reactive oxygen species biosynthetic process GO:1903426 5 0.010
regulation of nucleotide metabolic process GO:0006140 117 0.010
negative regulation of protein metabolic process GO:0051248 114 0.010
tissue regeneration GO:0042246 36 0.010

Mlph disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.011
disease of anatomical entity DOID:7 0 0.011
nervous system disease DOID:863 0 0.011