Rattus norvegicus

0 known processes

Fto

fat mass and obesity associated

(Aliases: RGD1305121)

Fto biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
oxoacid metabolic process GO:0043436 290 0.063
regulation of neurogenesis GO:0050767 247 0.050
regulation of multicellular organismal development GO:2000026 376 0.049
cellular ketone metabolic process GO:0042180 51 0.044
regulation of cellular amino acid metabolic process GO:0006521 2 0.040
regulation of cell projection organization GO:0031344 175 0.039
cellular component movement GO:0006928 248 0.038
regulation of cellular ketone metabolic process GO:0010565 27 0.038
cellular amino acid metabolic process GO:0006520 107 0.038
regulation of neuron projection development GO:0010975 161 0.037
single organism biosynthetic process GO:0044711 342 0.037
regulation of cellular amine metabolic process GO:0033238 8 0.036
response to nutrient levels GO:0031667 370 0.035
homeostatic process GO:0042592 331 0.035
cell projection organization GO:0030030 302 0.034
amine metabolic process GO:0009308 38 0.033
organic acid metabolic process GO:0006082 292 0.033
reproductive process GO:0022414 372 0.032
positive regulation of multicellular organismal process GO:0051240 387 0.032
regulation of cell differentiation GO:0045595 320 0.032
protein phosphorylation GO:0006468 345 0.031
positive regulation of response to stimulus GO:0048584 285 0.031
positive regulation of neurogenesis GO:0050769 165 0.031
chemical homeostasis GO:0048878 292 0.030
neuron projection development GO:0031175 273 0.030
protein complex biogenesis GO:0070271 263 0.030
positive regulation of neuron projection development GO:0010976 99 0.030
cellular amine metabolic process GO:0044106 38 0.029
cation transmembrane transport GO:0098655 263 0.029
transcription from rna polymerase ii promoter GO:0006366 252 0.028
central nervous system development GO:0007417 311 0.027
neuron differentiation GO:0030182 368 0.026
cation homeostasis GO:0055080 195 0.026
regulation of cell proliferation GO:0042127 359 0.026
regulation of nervous system development GO:0051960 264 0.025
ion transmembrane transport GO:0034220 365 0.025
positive regulation of cellular component organization GO:0051130 200 0.025
neuron development GO:0048666 286 0.025
transmembrane transport GO:0055085 412 0.025
intracellular transport GO:0046907 185 0.025
tissue development GO:0009888 252 0.025
regulation of cell development GO:0060284 263 0.024
growth GO:0040007 165 0.024
positive regulation of developmental process GO:0051094 283 0.024
nucleic acid templated transcription GO:0097659 379 0.024
positive regulation of cell development GO:0010720 176 0.024
cation transport GO:0006812 382 0.024
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.024
positive regulation of cell differentiation GO:0045597 217 0.024
carboxylic acid metabolic process GO:0019752 289 0.023
cellular chemical homeostasis GO:0055082 247 0.023
positive regulation of nervous system development GO:0051962 178 0.021
divalent inorganic cation homeostasis GO:0072507 165 0.021
ion homeostasis GO:0050801 212 0.021
regulation of anatomical structure morphogenesis GO:0022603 141 0.021
cellular ion homeostasis GO:0006873 184 0.021
regulation of cellular component organization GO:0051128 368 0.021
positive regulation of cell projection organization GO:0031346 111 0.021
cellular cation homeostasis GO:0030003 180 0.021
nitrogen compound transport GO:0071705 229 0.021
calcium ion homeostasis GO:0055074 162 0.020
positive regulation of rna metabolic process GO:0051254 203 0.020
eye morphogenesis GO:0048592 4 0.020
positive regulation of neuron differentiation GO:0045666 126 0.020
regulation of neuron differentiation GO:0045664 208 0.020
positive regulation of phosphorus metabolic process GO:0010562 262 0.020
aging GO:0007568 241 0.019
cellular homeostasis GO:0019725 252 0.019
regulation of signal transduction GO:0009966 318 0.019
regulation of phosphate metabolic process GO:0019220 349 0.019
cellular component biogenesis GO:0044085 368 0.018
cellular metal ion homeostasis GO:0006875 172 0.018
rna biosynthetic process GO:0032774 380 0.018
immune response GO:0006955 104 0.018
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.018
positive regulation of cellular biosynthetic process GO:0031328 295 0.018
multicellular organism growth GO:0035264 1 0.018
single organism intracellular transport GO:1902582 166 0.018
metal ion homeostasis GO:0055065 186 0.018
regulation of rna metabolic process GO:0051252 391 0.018
regulation of protein modification process GO:0031399 194 0.018
inorganic ion transmembrane transport GO:0098660 229 0.017
intracellular signal transduction GO:0035556 314 0.017
positive regulation of cellular amine metabolic process GO:0033240 3 0.017
response to peptide GO:1901652 292 0.017
regulation of cell morphogenesis involved in differentiation GO:0010769 72 0.017
cell growth GO:0016049 104 0.017
cellular divalent inorganic cation homeostasis GO:0072503 162 0.017
reproduction GO:0000003 245 0.017
cell cell signaling GO:0007267 335 0.017
small molecule biosynthetic process GO:0044283 124 0.017
positive regulation of phosphate metabolic process GO:0045937 262 0.017
cell cycle GO:0007049 101 0.017
brain development GO:0007420 247 0.017
positive regulation of signaling GO:0023056 270 0.017
regulation of phosphorus metabolic process GO:0051174 349 0.016
inorganic cation transmembrane transport GO:0098662 202 0.016
positive regulation of cell communication GO:0010647 271 0.016
response to carbohydrate GO:0009743 183 0.016
cellular calcium ion homeostasis GO:0006874 160 0.016
positive regulation of biosynthetic process GO:0009891 319 0.016
regulation of phosphorylation GO:0042325 248 0.015
protein transport GO:0015031 132 0.015
cellular response to nitrogen compound GO:1901699 210 0.015
response to extracellular stimulus GO:0009991 380 0.015
regulation of rna biosynthetic process GO:2001141 381 0.015
regulation of cellular protein metabolic process GO:0032268 267 0.015
negative regulation of cell communication GO:0010648 158 0.015
negative regulation of cellular metabolic process GO:0031324 281 0.014
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.014
positive regulation of molecular function GO:0044093 230 0.014
cell migration GO:0016477 197 0.014
regulation of dendrite development GO:0050773 59 0.014
cellular response to growth factor stimulus GO:0071363 162 0.014
positive regulation of rna biosynthetic process GO:1902680 197 0.014
protein oligomerization GO:0051259 191 0.014
secretion GO:0046903 307 0.014
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.014
response to growth factor GO:0070848 189 0.014
rna metabolic process GO:0016070 406 0.014
positive regulation of signal transduction GO:0009967 175 0.014
monocarboxylic acid metabolic process GO:0032787 152 0.014
protein complex assembly GO:0006461 263 0.013
negative regulation of transport GO:0051051 136 0.013
cell morphogenesis involved in differentiation GO:0000904 119 0.013
nucleotide metabolic process GO:0009117 279 0.013
lipid metabolic process GO:0006629 283 0.013
peptidyl amino acid modification GO:0018193 126 0.013
nucleobase containing small molecule metabolic process GO:0055086 316 0.013
response to oxygen levels GO:0070482 265 0.013
calcium ion transport GO:0006816 131 0.013
regulation of protein phosphorylation GO:0001932 183 0.013
cytoskeleton dependent cytokinesis GO:0061640 2 0.013
positive regulation of cell proliferation GO:0008284 249 0.013
positive regulation of ion transport GO:0043270 94 0.013
cytosolic calcium ion homeostasis GO:0051480 140 0.013
transcription dna templated GO:0006351 377 0.013
epithelium development GO:0060429 96 0.013
regulation of cell morphogenesis GO:0022604 77 0.013
single organism reproductive process GO:0044702 297 0.013
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 85 0.013
response to nutrient GO:0007584 248 0.013
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.013
positive regulation of nucleic acid templated transcription GO:1903508 197 0.013
secretion by cell GO:0032940 248 0.013
carbohydrate derivative biosynthetic process GO:1901137 124 0.013
single organism carbohydrate metabolic process GO:0044723 118 0.013
cellular component assembly GO:0022607 360 0.013
negative regulation of cell proliferation GO:0008285 119 0.013
mitotic spindle organization GO:0007052 2 0.013
ras protein signal transduction GO:0007265 29 0.013
regulation of molecular function GO:0065009 398 0.012
lipid biosynthetic process GO:0008610 128 0.012
establishment of tissue polarity GO:0007164 2 0.012
protein localization GO:0008104 191 0.012
negative regulation of metabolic process GO:0009892 331 0.012
negative regulation of neuron differentiation GO:0045665 62 0.012
enzyme linked receptor protein signaling pathway GO:0007167 116 0.012
cell morphogenesis involved in neuron differentiation GO:0048667 106 0.012
response to wounding GO:0009611 254 0.012
regulation of transcription dna templated GO:0006355 374 0.012
spindle organization GO:0007051 2 0.012
macromolecular complex subunit organization GO:0043933 339 0.012
neuron projection morphogenesis GO:0048812 122 0.012
multicellular organism reproduction GO:0032504 233 0.012
cellular carbohydrate metabolic process GO:0044262 72 0.012
regulation of cellular localization GO:0060341 263 0.012
regulation of protein metabolic process GO:0051246 289 0.012
positive regulation of cellular protein metabolic process GO:0032270 167 0.012
nucleoside phosphate metabolic process GO:0006753 283 0.012
positive regulation of intracellular signal transduction GO:1902533 138 0.012
response to vitamin GO:0033273 131 0.012
multicellular organismal reproductive process GO:0048609 233 0.012
carbohydrate derivative metabolic process GO:1901135 346 0.012
organophosphate biosynthetic process GO:0090407 143 0.012
negative regulation of cellular protein metabolic process GO:0032269 106 0.012
negative regulation of response to stimulus GO:0048585 155 0.012
regulation of nucleic acid templated transcription GO:1903506 380 0.012
divalent inorganic cation transport GO:0072511 134 0.012
regulation of metal ion transport GO:0010959 118 0.012
negative regulation of protein import into nucleus translocation GO:0033159 1 0.011
regulation of catalytic activity GO:0050790 304 0.011
regulation of ion transport GO:0043269 245 0.011
negative regulation of macromolecule metabolic process GO:0010605 260 0.011
maintenance of location GO:0051235 17 0.011
dendrite development GO:0016358 72 0.011
positive regulation of gene expression GO:0010628 244 0.011
adult locomotory behavior GO:0008344 4 0.011
microtubule organizing center organization GO:0031023 1 0.011
carbohydrate metabolic process GO:0005975 130 0.011
metal ion transport GO:0030001 289 0.011
defense response GO:0006952 194 0.011
response to organophosphorus GO:0046683 102 0.011
regulation of hormone levels GO:0010817 187 0.011
neuromuscular process GO:0050905 2 0.011
regulation of protein kinase activity GO:0045859 105 0.011
catabolic process GO:0009056 351 0.011
positive regulation of protein metabolic process GO:0051247 178 0.011
cellular response to oxygen containing compound GO:1901701 386 0.011
cellular response to stress GO:0033554 269 0.011
endomembrane system organization GO:0010256 48 0.011
regulation of anatomical structure size GO:0090066 135 0.011
positive regulation of catalytic activity GO:0043085 184 0.010
cell cell signaling involved in cell fate commitment GO:0045168 2 0.010
negative regulation of programmed cell death GO:0043069 183 0.010
response to acid chemical GO:0001101 222 0.010
regulation of membrane potential GO:0042391 110 0.010
blood circulation GO:0008015 183 0.010
regulation of growth GO:0040008 105 0.010
response to inorganic substance GO:0010035 377 0.010
apoptotic process GO:0006915 381 0.010
macromolecular complex assembly GO:0065003 273 0.010
lipid storage GO:0019915 1 0.010
response to radiation GO:0009314 137 0.010
regulation of apoptotic process GO:0042981 335 0.010
neuronal action potential GO:0019228 35 0.010
axon development GO:0061564 96 0.010
circulatory system process GO:0003013 183 0.010
inflammatory response GO:0006954 150 0.010
positive regulation of programmed cell death GO:0043068 157 0.010

Fto disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.017
disease of anatomical entity DOID:7 0 0.015
nervous system disease DOID:863 0 0.015
musculoskeletal system disease DOID:17 0 0.014
central nervous system disease DOID:331 0 0.011