Rattus norvegicus

0 known processes

LOC691289

similar to serine (or cysteine) proteinase inhibitor, clade B, member 1a

LOC691289 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cellular response to endogenous stimulus GO:0071495 377 0.268
circulatory system process GO:0003013 183 0.174
response to glucocorticoid GO:0051384 223 0.133
neurological system process GO:0050877 219 0.129
tissue development GO:0009888 252 0.090
response to extracellular stimulus GO:0009991 380 0.086
intracellular signal transduction GO:0035556 314 0.084
response to hypoxia GO:0001666 231 0.079
regulation of apoptotic process GO:0042981 335 0.074
regulation of multicellular organismal development GO:2000026 376 0.070
cellular response to organonitrogen compound GO:0071417 197 0.070
response to nutrient levels GO:0031667 370 0.065
cellular response to cytokine stimulus GO:0071345 127 0.063
positive regulation of response to stimulus GO:0048584 285 0.061
homeostatic process GO:0042592 331 0.060
response to peptide GO:1901652 292 0.060
positive regulation of cell proliferation GO:0008284 249 0.058
regulation of hormone levels GO:0010817 187 0.057
cellular response to organic cyclic compound GO:0071407 202 0.057
regulation of cell proliferation GO:0042127 359 0.056
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.054
blood circulation GO:0008015 183 0.053
positive regulation of programmed cell death GO:0043068 157 0.053
response to decreased oxygen levels GO:0036293 237 0.053
negative regulation of multicellular organismal process GO:0051241 203 0.053
regulation of cellular component organization GO:0051128 368 0.051
central nervous system development GO:0007417 311 0.048
regulation of cellular localization GO:0060341 263 0.048
cellular component assembly GO:0022607 360 0.048
regulation of intracellular signal transduction GO:1902531 218 0.047
negative regulation of metabolic process GO:0009892 331 0.044
cellular ketone metabolic process GO:0042180 51 0.044
positive regulation of phosphorus metabolic process GO:0010562 262 0.043
growth GO:0040007 165 0.043
cellular component biogenesis GO:0044085 368 0.042
cellular chemical homeostasis GO:0055082 247 0.041
chemical homeostasis GO:0048878 292 0.040
amine metabolic process GO:0009308 38 0.040
negative regulation of cell death GO:0060548 229 0.039
organic acid metabolic process GO:0006082 292 0.039
cellular amino acid metabolic process GO:0006520 107 0.038
cellular ion homeostasis GO:0006873 184 0.038
cellular response to nitrogen compound GO:1901699 210 0.038
cellular amine metabolic process GO:0044106 38 0.037
cell projection organization GO:0030030 302 0.037
positive regulation of signal transduction GO:0009967 175 0.037
rhythmic process GO:0048511 156 0.037
secretion by cell GO:0032940 248 0.035
positive regulation of multicellular organismal process GO:0051240 387 0.035
positive regulation of signaling GO:0023056 270 0.035
cellular cation homeostasis GO:0030003 180 0.035
response to peptide hormone GO:0043434 278 0.034
cellular homeostasis GO:0019725 252 0.034
positive regulation of phosphate metabolic process GO:0045937 262 0.034
cation transport GO:0006812 382 0.034
carboxylic acid metabolic process GO:0019752 289 0.033
response to inorganic substance GO:0010035 377 0.033
oxoacid metabolic process GO:0043436 290 0.032
cytokine production GO:0001816 61 0.030
response to monosaccharide GO:0034284 159 0.030
cellular response to growth factor stimulus GO:0071363 162 0.029
metal ion homeostasis GO:0055065 186 0.029
regulation of cellular amino acid metabolic process GO:0006521 2 0.029
aging GO:0007568 241 0.029
single organism biosynthetic process GO:0044711 342 0.028
action potential GO:0001508 54 0.028
nucleobase containing small molecule metabolic process GO:0055086 316 0.028
cation homeostasis GO:0055080 195 0.028
cellular metal ion homeostasis GO:0006875 172 0.028
positive regulation of cell death GO:0010942 184 0.027
lipid metabolic process GO:0006629 283 0.027
organic hydroxy compound metabolic process GO:1901615 115 0.027
programmed cell death GO:0012501 392 0.026
response to hexose GO:0009746 144 0.026
transmission of nerve impulse GO:0019226 42 0.026
positive regulation of developmental process GO:0051094 283 0.026
regulation of cellular amine metabolic process GO:0033238 8 0.026
divalent inorganic cation transport GO:0072511 134 0.026
lipid biosynthetic process GO:0008610 128 0.026
positive regulation of apoptotic process GO:0043065 154 0.025
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.025
calcium ion transport GO:0006816 131 0.025
single organism reproductive process GO:0044702 297 0.025
calcium ion homeostasis GO:0055074 162 0.025
response to oxygen levels GO:0070482 265 0.024
regulation of phosphate metabolic process GO:0019220 349 0.024
apoptotic process GO:0006915 381 0.023
positive regulation of cell development GO:0010720 176 0.023
response to cytokine GO:0034097 215 0.023
negative regulation of natural killer cell mediated cytotoxicity GO:0045953 4 0.022
negative regulation of biosynthetic process GO:0009890 168 0.022
positive regulation of gene expression GO:0010628 244 0.022
regulation of programmed cell death GO:0043067 341 0.022
inorganic ion transmembrane transport GO:0098660 229 0.022
ribose phosphate metabolic process GO:0019693 235 0.022
cellular response to lipid GO:0071396 201 0.022
response to corticosteroid GO:0031960 235 0.022
positive regulation of neuron projection development GO:0010976 99 0.021
response to purine containing compound GO:0014074 126 0.021
cellular response to oxygen containing compound GO:1901701 386 0.021
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.021
development of primary sexual characteristics GO:0045137 107 0.021
response to carbohydrate GO:0009743 183 0.021
positive regulation of cell communication GO:0010647 271 0.020
metal ion transport GO:0030001 289 0.020
response to lipopolysaccharide GO:0032496 191 0.020
alcohol metabolic process GO:0006066 77 0.020
response to estrogen GO:0043627 232 0.020
positive regulation of cellular component organization GO:0051130 200 0.020
negative regulation of macromolecule metabolic process GO:0010605 260 0.020
regulation of blood circulation GO:1903522 110 0.020
response to growth factor GO:0070848 189 0.020
rna metabolic process GO:0016070 406 0.019
nucleic acid templated transcription GO:0097659 379 0.019
positive regulation of cellular biosynthetic process GO:0031328 295 0.019
purine ribonucleotide metabolic process GO:0009150 227 0.019
negative regulation of cell development GO:0010721 82 0.019
regulation of signal transduction GO:0009966 318 0.019
developmental growth GO:0048589 100 0.019
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.019
sex differentiation GO:0007548 113 0.018
ion homeostasis GO:0050801 212 0.018
gamete generation GO:0007276 124 0.018
triglyceride homeostasis GO:0070328 2 0.018
multicellular organismal reproductive process GO:0048609 233 0.017
sensory perception GO:0007600 101 0.017
positive regulation of molecular function GO:0044093 230 0.017
positive regulation of biosynthetic process GO:0009891 319 0.017
protein complex subunit organization GO:0071822 302 0.017
purine nucleotide metabolic process GO:0006163 229 0.017
positive regulation of cell projection organization GO:0031346 111 0.017
regulation of membrane potential GO:0042391 110 0.017
cellular response to stress GO:0033554 269 0.017
neuronal action potential GO:0019228 35 0.016
response to nutrient GO:0007584 248 0.016
neuron development GO:0048666 286 0.016
response to external biotic stimulus GO:0043207 221 0.016
regulation of rna biosynthetic process GO:2001141 381 0.016
cellular component movement GO:0006928 248 0.016
inorganic cation transmembrane transport GO:0098662 202 0.016
cellular divalent inorganic cation homeostasis GO:0072503 162 0.016
brain development GO:0007420 247 0.016
ovulation cycle GO:0042698 67 0.016
regulation of cell differentiation GO:0045595 320 0.015
nucleotide metabolic process GO:0009117 279 0.015
macromolecular complex subunit organization GO:0043933 339 0.015
embryonic pattern specification GO:0009880 1 0.015
positive regulation of cellular amine metabolic process GO:0033240 3 0.015
cellular response to steroid hormone stimulus GO:0071383 93 0.015
cellular response to glucocorticoid stimulus GO:0071385 68 0.015
regulation of protein metabolic process GO:0051246 289 0.015
neuron differentiation GO:0030182 368 0.015
mapk cascade GO:0000165 140 0.015
peptidyl tyrosine phosphorylation GO:0018108 72 0.015
ribose phosphate biosynthetic process GO:0046390 87 0.015
developmental process involved in reproduction GO:0003006 159 0.015
immune effector process GO:0002252 53 0.015
catabolic process GO:0009056 351 0.015
divalent inorganic cation homeostasis GO:0072507 165 0.014
reproductive process GO:0022414 372 0.014
enzyme linked receptor protein signaling pathway GO:0007167 116 0.014
protein complex biogenesis GO:0070271 263 0.014
g protein coupled receptor signaling pathway GO:0007186 242 0.014
regeneration GO:0031099 163 0.014
regulation of neurogenesis GO:0050767 247 0.014
response to molecule of bacterial origin GO:0002237 194 0.014
regulation of cellular ketone metabolic process GO:0010565 27 0.014
nitrogen compound transport GO:0071705 229 0.014
small molecule biosynthetic process GO:0044283 124 0.014
regulation of synaptic transmission GO:0050804 141 0.014
cellular response to external stimulus GO:0071496 118 0.014
cytokine biosynthetic process GO:0042089 3 0.014
positive regulation of cytosolic calcium ion concentration GO:0007204 122 0.014
anion transport GO:0006820 178 0.014
transmembrane transport GO:0055085 412 0.014
regulation of cell development GO:0060284 263 0.013
nucleoside phosphate biosynthetic process GO:1901293 102 0.013
muscle cell proliferation GO:0033002 84 0.013
maintenance of location GO:0051235 17 0.013
response to starvation GO:0042594 59 0.013
purine containing compound metabolic process GO:0072521 253 0.013
transcription dna templated GO:0006351 377 0.013
response to amino acid GO:0043200 75 0.013
regulation of calcium ion transport GO:0051924 77 0.013
ribonucleotide metabolic process GO:0009259 231 0.013
positive regulation of cell differentiation GO:0045597 217 0.013
renin angiotensin regulation of aldosterone production GO:0002018 3 0.013
single organism catabolic process GO:0044712 283 0.013
cellular response to oxygen levels GO:0071453 60 0.013
reactive oxygen species biosynthetic process GO:1903409 8 0.013
leukocyte mediated immunity GO:0002443 28 0.013
multicellular organism reproduction GO:0032504 233 0.012
sequestering of metal ion GO:0051238 9 0.012
cell morphogenesis GO:0000902 142 0.012
regulation of anatomical structure size GO:0090066 135 0.012
regulation of molecular function GO:0065009 398 0.012
inflammatory response GO:0006954 150 0.012
response to bacterium GO:0009617 200 0.012
reproduction GO:0000003 245 0.012
cell part morphogenesis GO:0032990 123 0.012
immune response GO:0006955 104 0.012
carbohydrate derivative biosynthetic process GO:1901137 124 0.012
regulation of immunoglobulin production GO:0002637 4 0.012
nucleoside phosphate metabolic process GO:0006753 283 0.012
negative regulation of apoptotic process GO:0043066 181 0.012
reproductive structure development GO:0048608 128 0.012
regulation of anatomical structure morphogenesis GO:0022603 141 0.012
organophosphate biosynthetic process GO:0090407 143 0.012
regulation of tube size GO:0035150 89 0.012
cardiovascular system development GO:0072358 134 0.012
negative regulation of cellular metabolic process GO:0031324 281 0.012
multicellular organismal signaling GO:0035637 44 0.011
positive regulation of transcription dna templated GO:0045893 197 0.011
response to ethanol GO:0045471 162 0.011
asymmetric protein localization GO:0008105 2 0.011
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.011
negative regulation of defecation GO:2000293 1 0.011
positive regulation of transport GO:0051050 245 0.011
regulation of system process GO:0044057 208 0.011
organ formation GO:0048645 3 0.011
regulation of transcription dna templated GO:0006355 374 0.011
cell growth GO:0016049 104 0.011
cellular response to hormone stimulus GO:0032870 247 0.011
renal system development GO:0072001 67 0.011
response to radiation GO:0009314 137 0.011
single organism organelle organization GO:1902589 180 0.011
reactive nitrogen species metabolic process GO:2001057 1 0.011
nucleotide biosynthetic process GO:0009165 98 0.011
secretion GO:0046903 307 0.011
organic acid transport GO:0015849 116 0.010
wound healing GO:0042060 122 0.010
protein oligomerization GO:0051259 191 0.010
purine containing compound biosynthetic process GO:0072522 85 0.010
lipid storage GO:0019915 1 0.010
regulation of leukocyte proliferation GO:0070663 26 0.010
regulation of growth GO:0040008 105 0.010
defense response GO:0006952 194 0.010
negative regulation of cellular biosynthetic process GO:0031327 161 0.010
regulation of reactive oxygen species metabolic process GO:2000377 26 0.010
potassium ion transmembrane transport GO:0071805 71 0.010
organophosphate metabolic process GO:0019637 370 0.010
organic hydroxy compound biosynthetic process GO:1901617 51 0.010
regulation of neuron projection development GO:0010975 161 0.010
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.010
carbohydrate derivative metabolic process GO:1901135 346 0.010
cell cell signaling GO:0007267 335 0.010
response to mechanical stimulus GO:0009612 134 0.010
negative regulation of gene expression GO:0010629 199 0.010

LOC691289 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of cellular proliferation DOID:14566 0 0.022
organ system cancer DOID:0050686 0 0.019
cancer DOID:162 0 0.019
colon carcinoma DOID:1520 0 0.012
gastrointestinal system cancer DOID:3119 0 0.012
intestinal cancer DOID:10155 0 0.012
colorectal cancer DOID:9256 0 0.012
colon cancer DOID:219 0 0.012
large intestine cancer DOID:5672 0 0.012
disease of anatomical entity DOID:7 0 0.011
nervous system disease DOID:863 0 0.011
endocrine system disease DOID:28 0 0.011