Rattus norvegicus

16 known processes

Hgs

hepatocyte growth factor-regulated tyrosine kinase substrate

(Aliases: Hrs)

Hgs biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
vesicle mediated transport GO:0016192 181 0.110
single organism intracellular transport GO:1902582 166 0.074
positive regulation of cell communication GO:0010647 271 0.074
cell projection organization GO:0030030 302 0.069
neuron development GO:0048666 286 0.062
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.054
regulation of phosphorus metabolic process GO:0051174 349 0.052
carboxylic acid metabolic process GO:0019752 289 0.052
nitrogen compound transport GO:0071705 229 0.051
regulation of phosphate metabolic process GO:0019220 349 0.050
carbohydrate derivative metabolic process GO:1901135 346 0.049
regulation of multicellular organismal development GO:2000026 376 0.048
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.043
programmed cell death GO:0012501 392 0.042
regulation of rna metabolic process GO:0051252 391 0.041
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.040
spindle organization GO:0007051 2 0.038
intracellular signal transduction GO:0035556 314 0.038
response to peptide hormone GO:0043434 278 0.038
positive regulation of signaling GO:0023056 270 0.038
macromolecule localization GO:0033036 252 0.037
cellular catabolic process GO:0044248 295 0.037
ribonucleotide metabolic process GO:0009259 231 0.037
positive regulation of phosphorus metabolic process GO:0010562 262 0.037
regulation of molecular function GO:0065009 398 0.036
purine ribonucleoside metabolic process GO:0046128 168 0.035
cellular component assembly GO:0022607 360 0.035
regulation of cell differentiation GO:0045595 320 0.035
nucleobase containing small molecule metabolic process GO:0055086 316 0.035
positive regulation of catalytic activity GO:0043085 184 0.035
cellular component movement GO:0006928 248 0.035
rna metabolic process GO:0016070 406 0.034
regulation of catalytic activity GO:0050790 304 0.034
regulation of neurogenesis GO:0050767 247 0.034
regulation of nervous system development GO:0051960 264 0.034
regulation of catabolic process GO:0009894 113 0.033
purine nucleoside metabolic process GO:0042278 169 0.033
tissue development GO:0009888 252 0.033
regulation of hydrolase activity GO:0051336 143 0.032
positive regulation of molecular function GO:0044093 230 0.032
response to inorganic substance GO:0010035 377 0.032
ribose phosphate metabolic process GO:0019693 235 0.031
negative regulation of macromolecule metabolic process GO:0010605 260 0.031
regulation of nucleotide catabolic process GO:0030811 65 0.031
organic substance catabolic process GO:1901575 316 0.031
regulation of cellular ketone metabolic process GO:0010565 27 0.030
nucleoside phosphate metabolic process GO:0006753 283 0.030
purine containing compound metabolic process GO:0072521 253 0.029
intracellular transport GO:0046907 185 0.029
central nervous system development GO:0007417 311 0.029
positive regulation of purine nucleotide metabolic process GO:1900544 91 0.029
reproductive process GO:0022414 372 0.029
catabolic process GO:0009056 351 0.028
regulation of mrna splicing via spliceosome GO:0048024 3 0.028
purine nucleoside triphosphate metabolic process GO:0009144 141 0.028
nucleoside triphosphate catabolic process GO:0009143 123 0.027
tube development GO:0035295 89 0.027
amine metabolic process GO:0009308 38 0.027
neuron differentiation GO:0030182 368 0.027
divalent inorganic cation transport GO:0072511 134 0.027
neuron projection development GO:0031175 273 0.027
ribonucleotide catabolic process GO:0009261 136 0.027
regulation of cellular localization GO:0060341 263 0.026
apoptotic process GO:0006915 381 0.026
regulation of apoptotic process GO:0042981 335 0.026
regulation of nucleic acid templated transcription GO:1903506 380 0.026
regulation of phosphorylation GO:0042325 248 0.025
anatomical structure morphogenesis GO:0009653 298 0.025
response to other organism GO:0051707 220 0.025
positive regulation of phosphate metabolic process GO:0045937 262 0.025
heterocycle catabolic process GO:0046700 167 0.025
positive regulation of transcription dna templated GO:0045893 197 0.024
response to metal ion GO:0010038 253 0.024
guanosine containing compound metabolic process GO:1901068 74 0.024
regulation of cellular amino acid metabolic process GO:0006521 2 0.024
purine ribonucleoside triphosphate metabolic process GO:0009205 140 0.024
purine ribonucleotide catabolic process GO:0009154 136 0.024
establishment of vesicle localization GO:0051650 31 0.024
response to acid chemical GO:0001101 222 0.023
response to peptide GO:1901652 292 0.023
positive regulation of response to stimulus GO:0048584 285 0.023
purine ribonucleotide metabolic process GO:0009150 227 0.023
nucleotide metabolic process GO:0009117 279 0.023
organic acid metabolic process GO:0006082 292 0.023
organonitrogen compound catabolic process GO:1901565 179 0.023
cellular component biogenesis GO:0044085 368 0.023
cellular amine metabolic process GO:0044106 38 0.023
negative regulation of metabolic process GO:0009892 331 0.023
protein phosphorylation GO:0006468 345 0.022
secretion GO:0046903 307 0.022
response to wounding GO:0009611 254 0.022
protein complex biogenesis GO:0070271 263 0.022
organic cyclic compound catabolic process GO:1901361 175 0.022
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.022
single organism catabolic process GO:0044712 283 0.021
cellular amino acid metabolic process GO:0006520 107 0.021
gtp metabolic process GO:0046039 72 0.021
purine nucleoside catabolic process GO:0006152 124 0.021
g protein coupled receptor signaling pathway GO:0007186 242 0.021
protein complex assembly GO:0006461 263 0.021
organelle organization GO:0006996 266 0.021
glycosyl compound catabolic process GO:1901658 126 0.021
regulation of cellular amine metabolic process GO:0033238 8 0.021
positive regulation of cell proliferation GO:0008284 249 0.020
positive regulation of rna metabolic process GO:0051254 203 0.020
cation transmembrane transport GO:0098655 263 0.020
glycosyl compound metabolic process GO:1901657 182 0.020
growth GO:0040007 165 0.020
oxoacid metabolic process GO:0043436 290 0.020
regulation of cellular component organization GO:0051128 368 0.020
positive regulation of cellular component organization GO:0051130 200 0.020
positive regulation of protein metabolic process GO:0051247 178 0.020
response to biotic stimulus GO:0009607 226 0.020
cell part morphogenesis GO:0032990 123 0.020
cellular ketone metabolic process GO:0042180 51 0.020
regulation of purine nucleotide catabolic process GO:0033121 65 0.020
regeneration GO:0031099 163 0.020
positive regulation of cellular biosynthetic process GO:0031328 295 0.019
cation transport GO:0006812 382 0.019
purine nucleotide catabolic process GO:0006195 136 0.019
regulation of neuron differentiation GO:0045664 208 0.019
aging GO:0007568 241 0.019
purine ribonucleoside catabolic process GO:0046130 124 0.019
purine nucleotide metabolic process GO:0006163 229 0.019
neural crest cell development GO:0014032 2 0.019
regulation of purine nucleotide metabolic process GO:1900542 115 0.019
nucleoside triphosphate metabolic process GO:0009141 144 0.019
regulation of signal transduction GO:0009966 318 0.019
purine ribonucleoside triphosphate catabolic process GO:0009207 122 0.019
cell adhesion GO:0007155 110 0.019
aromatic compound catabolic process GO:0019439 168 0.019
positive regulation of nucleoside metabolic process GO:0045979 55 0.019
response to estradiol GO:0032355 164 0.019
epithelium development GO:0060429 96 0.019
biological adhesion GO:0022610 110 0.018
regulation of cell projection organization GO:0031344 175 0.018
nucleic acid templated transcription GO:0097659 379 0.018
positive regulation of nucleotide metabolic process GO:0045981 91 0.018
cellular response to organonitrogen compound GO:0071417 197 0.018
metal ion transport GO:0030001 289 0.018
positive regulation of phosphorylation GO:0042327 177 0.018
response to nutrient levels GO:0031667 370 0.018
axis specification GO:0009798 4 0.018
positive regulation of developmental process GO:0051094 283 0.018
alternative mrna splicing via spliceosome GO:0000380 4 0.018
ribonucleoside triphosphate metabolic process GO:0009199 141 0.018
macromolecular complex assembly GO:0065003 273 0.018
regulation of cell development GO:0060284 263 0.017
embryonic pattern specification GO:0009880 1 0.017
divalent metal ion transport GO:0070838 132 0.017
multicellular organismal reproductive process GO:0048609 233 0.017
multi organism reproductive process GO:0044703 262 0.017
response to extracellular stimulus GO:0009991 380 0.017
nucleoside metabolic process GO:0009116 179 0.017
secretion by cell GO:0032940 248 0.017
multicellular organism reproduction GO:0032504 233 0.017
response to external biotic stimulus GO:0043207 221 0.017
monocarboxylic acid metabolic process GO:0032787 152 0.017
positive regulation of transport GO:0051050 245 0.017
response to lipopolysaccharide GO:0032496 191 0.017
synaptic vesicle endocytosis GO:0048488 4 0.017
single organism reproductive process GO:0044702 297 0.017
regulation of cell motility GO:2000145 131 0.016
regulation of transcription dna templated GO:0006355 374 0.016
reproduction GO:0000003 245 0.016
positive regulation of hydrolase activity GO:0051345 86 0.016
regulation of neuron projection development GO:0010975 161 0.016
protein complex subunit organization GO:0071822 302 0.016
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.016
nucleobase containing compound catabolic process GO:0034655 152 0.016
transmembrane transport GO:0055085 412 0.016
sexual reproduction GO:0019953 148 0.016
response to bacterium GO:0009617 200 0.016
ras protein signal transduction GO:0007265 29 0.016
cellular response to oxygen containing compound GO:1901701 386 0.016
response to oxidative stress GO:0006979 186 0.016
protein oligomerization GO:0051259 191 0.016
anterior posterior pattern specification GO:0009952 1 0.016
regulation of protein metabolic process GO:0051246 289 0.015
response to amino acid GO:0043200 75 0.015
rna biosynthetic process GO:0032774 380 0.015
immune system process GO:0002376 204 0.015
gtp catabolic process GO:0006184 71 0.015
regulation of system process GO:0044057 208 0.015
lipid metabolic process GO:0006629 283 0.015
positive regulation of cellular amine metabolic process GO:0033240 3 0.015
regulation of secretion by cell GO:1903530 208 0.015
cell morphogenesis GO:0000902 142 0.015
synaptic transmission GO:0007268 235 0.015
regulation of vesicle mediated transport GO:0060627 81 0.015
negative regulation of multicellular organismal process GO:0051241 203 0.015
neurological system process GO:0050877 219 0.014
neuron death GO:0070997 127 0.014
regulation of gtpase activity GO:0043087 57 0.014
developmental process involved in reproduction GO:0003006 159 0.014
regulation of gtp catabolic process GO:0033124 58 0.014
response to molecule of bacterial origin GO:0002237 194 0.014
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.014
positive regulation of biosynthetic process GO:0009891 319 0.014
ribonucleoside triphosphate catabolic process GO:0009203 122 0.014
response to transition metal nanoparticle GO:1990267 122 0.014
response to monosaccharide GO:0034284 159 0.014
response to nutrient GO:0007584 248 0.014
ribonucleoside metabolic process GO:0009119 174 0.014
carbohydrate derivative catabolic process GO:1901136 147 0.014
chemical homeostasis GO:0048878 292 0.014
regulation of programmed cell death GO:0043067 341 0.014
protein localization GO:0008104 191 0.014
positive regulation of gtpase activity GO:0043547 47 0.014
positive regulation of gene expression GO:0010628 244 0.014
head development GO:0060322 247 0.014
positive regulation of signal transduction GO:0009967 175 0.013
organic anion transport GO:0015711 132 0.013
regulation of alternative mrna splicing via spliceosome GO:0000381 2 0.013
guanosine containing compound catabolic process GO:1901069 71 0.013
positive regulation of nervous system development GO:0051962 178 0.013
regulation of protein phosphorylation GO:0001932 183 0.013
cell projection morphogenesis GO:0048858 123 0.013
positive regulation of cell differentiation GO:0045597 217 0.013
regulation of rna biosynthetic process GO:2001141 381 0.013
cellular macromolecule localization GO:0070727 122 0.013
gamete generation GO:0007276 124 0.013
carboxylic acid transport GO:0046942 115 0.013
multicellular organism growth GO:0035264 1 0.013
purine containing compound catabolic process GO:0072523 138 0.013
regulation of nucleotide metabolic process GO:0006140 117 0.013
response to oxygen levels GO:0070482 265 0.013
cell motility GO:0048870 202 0.013
negative regulation of innate immune response GO:0045824 4 0.013
positive regulation of secretion by cell GO:1903532 128 0.013
regulation of ion transport GO:0043269 245 0.013
response to ethanol GO:0045471 162 0.013
hormone secretion GO:0046879 115 0.013
regulation of cellular protein metabolic process GO:0032268 267 0.013
positive regulation of purine nucleotide catabolic process GO:0033123 53 0.013
cellular response to stress GO:0033554 269 0.013
negative regulation of developmental process GO:0051093 125 0.013
negative regulation of cellular metabolic process GO:0031324 281 0.013
positive regulation of nucleotide catabolic process GO:0030813 53 0.013
immune response GO:0006955 104 0.013
macromolecular complex subunit organization GO:0043933 339 0.012
rna localization GO:0006403 4 0.012
cellular response to lipid GO:0071396 201 0.012
small gtpase mediated signal transduction GO:0007264 36 0.012
cellular divalent inorganic cation homeostasis GO:0072503 162 0.012
regulation of cell proliferation GO:0042127 359 0.012
oxidation reduction process GO:0055114 304 0.012
localization of cell GO:0051674 202 0.012
organophosphate metabolic process GO:0019637 370 0.012
maintenance of location GO:0051235 17 0.012
single organism cellular localization GO:1902580 102 0.012
positive regulation of neurogenesis GO:0050769 165 0.012
neural crest cell differentiation GO:0014033 2 0.012
mrna metabolic process GO:0016071 20 0.012
cellular response to nitrogen compound GO:1901699 210 0.012
response to hypoxia GO:0001666 231 0.012
female pregnancy GO:0007565 122 0.012
brain development GO:0007420 247 0.012
regulation of transferase activity GO:0051338 123 0.011
response to decreased oxygen levels GO:0036293 237 0.011
mitotic spindle organization GO:0007052 2 0.011
intracellular protein transport GO:0006886 79 0.011
negative regulation of cell death GO:0060548 229 0.011
cytoplasmic transport GO:0016482 115 0.011
cell cell signaling GO:0007267 335 0.011
regulation of intracellular signal transduction GO:1902531 218 0.011
negative regulation of gene expression GO:0010629 199 0.011
negative regulation of apoptotic process GO:0043066 181 0.011
circadian regulation of gene expression GO:0032922 3 0.011
positive regulation of multicellular organismal process GO:0051240 387 0.011
peptidyl tyrosine modification GO:0018212 72 0.011
negative regulation of programmed cell death GO:0043069 183 0.011
cellular chemical homeostasis GO:0055082 247 0.011
cellular homeostasis GO:0019725 252 0.011
regulation of nucleoside metabolic process GO:0009118 66 0.011
enzyme linked receptor protein signaling pathway GO:0007167 116 0.011
purine nucleoside triphosphate catabolic process GO:0009146 122 0.011
cellular ion homeostasis GO:0006873 184 0.011
negative regulation of rna splicing GO:0033119 3 0.011
lens development in camera type eye GO:0002088 13 0.011
ion transmembrane transport GO:0034220 365 0.011
positive regulation of cell development GO:0010720 176 0.011
cellular nitrogen compound catabolic process GO:0044270 163 0.011
synaptic growth at neuromuscular junction GO:0051124 1 0.011
cytoskeleton organization GO:0007010 111 0.011
muscle contraction GO:0006936 88 0.010
cellular lipid metabolic process GO:0044255 208 0.010
negative regulation of transport GO:0051051 136 0.010
muscle system process GO:0003012 115 0.010
positive regulation of rna biosynthetic process GO:1902680 197 0.010
signal transduction by phosphorylation GO:0023014 144 0.010
single organism membrane organization GO:0044802 74 0.010

Hgs disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.023
nervous system disease DOID:863 0 0.023
musculoskeletal system disease DOID:17 0 0.011
central nervous system disease DOID:331 0 0.010
neuromuscular disease DOID:440 0 0.010
charcot marie tooth disease type 2 DOID:0050539 0 0.010
charcot marie tooth disease DOID:10595 0 0.010
neuropathy DOID:870 0 0.010