Rattus norvegicus

107 known processes

Hgf

hepatocyte growth factor

(Aliases: HPTA)

Hgf biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
response to inorganic substance GO:0010035 377 0.175
Human
development of primary female sexual characteristics GO:0046545 56 0.168
regulation of programmed cell death GO:0043067 341 0.140
female gonad development GO:0008585 53 0.115
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.100
Human
reproductive process GO:0022414 372 0.092
Rat
regulation of signal transduction GO:0009966 318 0.092
Human Mouse
anatomical structure formation involved in morphogenesis GO:0048646 83 0.091
multicellular organismal reproductive process GO:0048609 233 0.082
Rat
response to oxygen levels GO:0070482 265 0.077
Rat
positive regulation of cellular biosynthetic process GO:0031328 295 0.075
Human
cell type specific apoptotic process GO:0097285 134 0.074
positive regulation of response to stimulus GO:0048584 285 0.072
negative regulation of metabolic process GO:0009892 331 0.072
Human
apoptotic process GO:0006915 381 0.070
regulation of rna biosynthetic process GO:2001141 381 0.068
positive regulation of phosphate metabolic process GO:0045937 262 0.068
Human Mouse
cell activation GO:0001775 97 0.068
regulation of nucleic acid templated transcription GO:1903506 380 0.067
neuron development GO:0048666 286 0.066
multicellular organism reproduction GO:0032504 233 0.065
Rat
feeding behavior GO:0007631 53 0.064
sexual reproduction GO:0019953 148 0.064
Rat
response to hypoxia GO:0001666 231 0.063
Rat
blood vessel morphogenesis GO:0048514 58 0.062
cyclic nucleotide metabolic process GO:0009187 80 0.062
female sex differentiation GO:0046660 59 0.059
intracellular signal transduction GO:0035556 314 0.058
Human Mouse
regulation of anatomical structure morphogenesis GO:0022603 141 0.058
cellular modified amino acid metabolic process GO:0006575 61 0.058
response to external biotic stimulus GO:0043207 221 0.056
Rat
circulatory system process GO:0003013 183 0.056
adenylate cyclase modulating g protein coupled receptor signaling pathway GO:0007188 51 0.055
g protein coupled receptor signaling pathway coupled to cyclic nucleotide second messenger GO:0007187 55 0.055
macromolecular complex subunit organization GO:0043933 339 0.054
regulation of system process GO:0044057 208 0.054
positive regulation of intracellular signal transduction GO:1902533 138 0.052
Human Mouse
homeostatic process GO:0042592 331 0.051
Rat
positive regulation of developmental process GO:0051094 283 0.050
cell cell signaling GO:0007267 335 0.050
Human Mouse Rat
regulation of blood pressure GO:0008217 83 0.050
positive regulation of transcription dna templated GO:0045893 197 0.049
leukocyte activation GO:0045321 76 0.049
lymphocyte activation GO:0046649 43 0.049
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.047
Human
cardiovascular system development GO:0072358 134 0.047
nucleoside phosphate metabolic process GO:0006753 283 0.046
response to metal ion GO:0010038 253 0.046
programmed cell death GO:0012501 392 0.046
response to growth factor GO:0070848 189 0.046
Human Rat
protein complex subunit organization GO:0071822 302 0.045
regulation of cellular component movement GO:0051270 150 0.044
Human Rat
limb morphogenesis GO:0035108 4 0.042
g protein coupled receptor signaling pathway GO:0007186 242 0.042
regulation of cell motility GO:2000145 131 0.042
Human Rat
nucleotide biosynthetic process GO:0009165 98 0.042
tissue development GO:0009888 252 0.041
Human Mouse Rat
positive regulation of gene expression GO:0010628 244 0.040
sex differentiation GO:0007548 113 0.040
regulation of leukocyte activation GO:0002694 45 0.040
circulatory system development GO:0072359 134 0.039
response to hexose GO:0009746 144 0.038
Rat
reproduction GO:0000003 245 0.038
Rat
response to corticosteroid GO:0031960 235 0.038
Rat
cellular response to nitrogen compound GO:1901699 210 0.037
Rat
ribonucleotide biosynthetic process GO:0009260 85 0.037
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.037
Human
regulation of catalytic activity GO:0050790 304 0.037
Human Mouse
single organism reproductive process GO:0044702 297 0.037
Rat
development of primary sexual characteristics GO:0045137 107 0.036
nucleoside phosphate biosynthetic process GO:1901293 102 0.036
positive regulation of protein metabolic process GO:0051247 178 0.036
Human Mouse
multi organism reproductive process GO:0044703 262 0.036
Rat
regulation of molecular function GO:0065009 398 0.035
Human Mouse
regulation of phosphate metabolic process GO:0019220 349 0.035
Human Mouse
regulation of apoptotic process GO:0042981 335 0.035
regulation of cell proliferation GO:0042127 359 0.034
Rat
response to extracellular stimulus GO:0009991 380 0.034
gamete generation GO:0007276 124 0.034
Rat
regulation of cellular protein metabolic process GO:0032268 267 0.034
Human Mouse
rna metabolic process GO:0016070 406 0.034
reproductive system development GO:0061458 128 0.033
cellular response to endogenous stimulus GO:0071495 377 0.033
Rat
positive regulation of cellular protein metabolic process GO:0032270 167 0.033
Human Mouse
cellular response to hexose stimulus GO:0071331 65 0.033
Rat
nucleotide metabolic process GO:0009117 279 0.032
cellular ketone metabolic process GO:0042180 51 0.032
cytokine production GO:0001816 61 0.032
macromolecule localization GO:0033036 252 0.032
aging GO:0007568 241 0.031
cellular component morphogenesis GO:0032989 155 0.031
Mouse
purine nucleotide metabolic process GO:0006163 229 0.031
rna biosynthetic process GO:0032774 380 0.031
defense response GO:0006952 194 0.031
cellular response to growth factor stimulus GO:0071363 162 0.030
Human Rat
positive regulation of protein serine threonine kinase activity GO:0071902 52 0.030
Mouse
positive regulation of biosynthetic process GO:0009891 319 0.029
Human
muscle cell differentiation GO:0042692 52 0.029
catabolic process GO:0009056 351 0.029
Rat
nucleic acid templated transcription GO:0097659 379 0.029
positive regulation of ion transport GO:0043270 94 0.029
female pregnancy GO:0007565 122 0.028
Rat
cellular response to oxygen containing compound GO:1901701 386 0.028
Human Rat
positive regulation of catalytic activity GO:0043085 184 0.028
Mouse
immune effector process GO:0002252 53 0.028
cellular component assembly GO:0022607 360 0.027
regulation of cellular localization GO:0060341 263 0.027
response to monosaccharide GO:0034284 159 0.027
Rat
cyclic nucleotide biosynthetic process GO:0009190 63 0.027
regulation of phosphorus metabolic process GO:0051174 349 0.027
Human Mouse
regulation of immune system process GO:0002682 123 0.026
cellular response to organonitrogen compound GO:0071417 197 0.026
Rat
positive regulation of cell projection organization GO:0031346 111 0.026
blood vessel development GO:0001568 69 0.026
negative regulation of cell proliferation GO:0008285 119 0.026
response to decreased oxygen levels GO:0036293 237 0.026
Rat
response to hydrogen peroxide GO:0042542 89 0.026
Human
positive regulation of rna biosynthetic process GO:1902680 197 0.025
actin cytoskeleton organization GO:0030036 73 0.025
spermatogenesis GO:0007283 99 0.025
Rat
locomotion GO:0040011 237 0.025
Human Zebrafish Rat
multicellular organism growth GO:0035264 1 0.025
response to biotic stimulus GO:0009607 226 0.025
Rat
cellular component movement GO:0006928 248 0.025
Human Zebrafish Rat
regulation of cell activation GO:0050865 50 0.025
calcium ion homeostasis GO:0055074 162 0.024
appendage morphogenesis GO:0035107 4 0.024
reproductive structure development GO:0048608 128 0.024
protein phosphorylation GO:0006468 345 0.024
Human Mouse
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.024
neuron differentiation GO:0030182 368 0.024
anatomical structure morphogenesis GO:0009653 298 0.024
ribonucleotide metabolic process GO:0009259 231 0.023
positive regulation of signal transduction GO:0009967 175 0.023
Human Mouse
positive regulation of immune system process GO:0002684 90 0.023
regulation of hydrolase activity GO:0051336 143 0.023
Human
gonad development GO:0008406 104 0.022
brain development GO:0007420 247 0.022
Zebrafish
cyclic purine nucleotide metabolic process GO:0052652 62 0.022
negative regulation of macromolecule metabolic process GO:0010605 260 0.022
Human
positive regulation of protein phosphorylation GO:0001934 135 0.022
Human Mouse
response to nutrient levels GO:0031667 370 0.022
protein complex biogenesis GO:0070271 263 0.022
cellular ion homeostasis GO:0006873 184 0.021
carbohydrate derivative metabolic process GO:1901135 346 0.021
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.021
vasculature development GO:0001944 70 0.021
cellular response to lipopolysaccharide GO:0071222 55 0.021
Rat
regulation of homeostatic process GO:0032844 101 0.021
purine nucleotide biosynthetic process GO:0006164 83 0.021
muscle structure development GO:0061061 87 0.021
camp biosynthetic process GO:0006171 47 0.020
localization of cell GO:0051674 202 0.020
Human Zebrafish Rat
response to glucose GO:0009749 136 0.020
Rat
regulation of metal ion transport GO:0010959 118 0.020
regulation of intracellular signal transduction GO:1902531 218 0.020
Human Mouse
morphogenesis of an epithelium GO:0002009 20 0.020
Human Mouse
negative regulation of cellular biosynthetic process GO:0031327 161 0.019
ion transmembrane transport GO:0034220 365 0.019
response to cytokine GO:0034097 215 0.019
synaptic transmission GO:0007268 235 0.019
Rat
insecticide metabolic process GO:0017143 4 0.019
positive regulation of phosphorus metabolic process GO:0010562 262 0.019
Human Mouse
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.019
positive regulation of immunoglobulin mediated immune response GO:0002891 2 0.019
positive regulation of cyclic nucleotide metabolic process GO:0030801 37 0.019
negative regulation of multicellular organismal process GO:0051241 203 0.019
regulation of cellular amine metabolic process GO:0033238 8 0.019
cytoskeleton organization GO:0007010 111 0.019
protein autophosphorylation GO:0046777 66 0.019
proteolysis GO:0006508 175 0.018
Human Rat
response to other organism GO:0051707 220 0.018
Rat
organophosphate metabolic process GO:0019637 370 0.018
protein complex assembly GO:0006461 263 0.018
actin filament based process GO:0030029 86 0.018
renal response to blood flow involved in circulatory renin angiotensin regulation of systemic arterial blood pressure GO:0001999 1 0.018
chemical homeostasis GO:0048878 292 0.018
Rat
developmental process involved in reproduction GO:0003006 159 0.018
lipid transport GO:0006869 61 0.018
purine ribonucleotide biosynthetic process GO:0009152 81 0.018
macromolecular complex assembly GO:0065003 273 0.018
sensory perception GO:0007600 101 0.018
regulation of transcription dna templated GO:0006355 374 0.018
carbohydrate homeostasis GO:0033500 75 0.018
Rat
transcription dna templated GO:0006351 377 0.018
organelle organization GO:0006996 266 0.018
Human
response to reactive oxygen species GO:0000302 120 0.018
Human
single organism biosynthetic process GO:0044711 342 0.017
positive regulation of phosphorylation GO:0042327 177 0.017
Human Mouse
secretion by cell GO:0032940 248 0.017
angiogenesis GO:0001525 53 0.017
cellular amino acid metabolic process GO:0006520 107 0.017
negative regulation of response to stimulus GO:0048585 155 0.017
Human Mouse
cellular response to glucocorticoid stimulus GO:0071385 68 0.017
Rat
cellular response to molecule of bacterial origin GO:0071219 56 0.017
Rat
lipid localization GO:0010876 62 0.017
protein homooligomerization GO:0051260 91 0.017
single organism organelle organization GO:1902589 180 0.017
cell motility GO:0048870 202 0.017
Human Zebrafish Rat
immune system process GO:0002376 204 0.017
regulation of locomotion GO:0040012 148 0.017
Human Rat
response to bacterium GO:0009617 200 0.017
Rat
response to acid chemical GO:0001101 222 0.016
cellular catabolic process GO:0044248 295 0.016
Rat
carbohydrate derivative biosynthetic process GO:1901137 124 0.016
ribose phosphate biosynthetic process GO:0046390 87 0.016
purine ribonucleotide metabolic process GO:0009150 227 0.016
sulfur amino acid metabolic process GO:0000096 9 0.016
immune response to tumor cell GO:0002418 3 0.016
protein heterooligomerization GO:0051291 89 0.016
tumor necrosis factor mediated signaling pathway GO:0033209 4 0.016
secretion GO:0046903 307 0.016
receptor metabolic process GO:0043112 18 0.016
positive regulation of cell differentiation GO:0045597 217 0.015
cellular response to oxidative stress GO:0034599 76 0.015
Human
small gtpase mediated signal transduction GO:0007264 36 0.015
intracellular transport GO:0046907 185 0.015
cholesterol homeostasis GO:0042632 3 0.015
purine containing compound biosynthetic process GO:0072522 85 0.015
regulation of behavior GO:0050795 61 0.015
defense response to gram negative bacterium GO:0050829 3 0.015
carboxylic acid metabolic process GO:0019752 289 0.015
regulation of protein modification process GO:0031399 194 0.015
Human Mouse
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.015
positive regulation of neuron projection development GO:0010976 99 0.015
positive regulation of immunoglobulin production GO:0002639 4 0.015
positive regulation of purine nucleotide biosynthetic process GO:1900373 36 0.015
positive regulation of cyclic nucleotide biosynthetic process GO:0030804 34 0.015
cellular metal ion homeostasis GO:0006875 172 0.015
protein oligomerization GO:0051259 191 0.015
fatty acid transport GO:0015908 25 0.015
hepaticobiliary system development GO:0061008 90 0.015
Mouse Rat
regulation of cellular amino acid metabolic process GO:0006521 2 0.014
positive regulation of cytokine production GO:0001819 42 0.014
positive regulation of cell activation GO:0050867 34 0.014
response to lipopolysaccharide GO:0032496 191 0.014
Rat
oxoacid metabolic process GO:0043436 290 0.014
positive regulation of signaling GO:0023056 270 0.014
Human Mouse
regulation of cellular ketone metabolic process GO:0010565 27 0.014
male gamete generation GO:0048232 99 0.014
Rat
regulation of response to external stimulus GO:0032101 106 0.014
response to molecule of bacterial origin GO:0002237 194 0.014
Rat
positive regulation of neurogenesis GO:0050769 165 0.014
cellular response to monosaccharide stimulus GO:0071326 67 0.014
Rat
embryonic pattern specification GO:0009880 1 0.014
organic acid metabolic process GO:0006082 292 0.014
potassium ion transport GO:0006813 97 0.014
positive regulation of cell proliferation GO:0008284 249 0.014
Rat
cellular amine metabolic process GO:0044106 38 0.014
positive regulation of b cell mediated immunity GO:0002714 2 0.014
regulation of phosphorylation GO:0042325 248 0.014
Human Mouse
cellular response to glucose stimulus GO:0071333 65 0.014
Rat
negative regulation of phosphate metabolic process GO:0045936 80 0.014
negative regulation of gene expression GO:0010629 199 0.014
Human
immune response GO:0006955 104 0.014
cellular response to metal ion GO:0071248 55 0.014
regulation of membrane potential GO:0042391 110 0.013
male sex differentiation GO:0046661 64 0.013
regulation of rna metabolic process GO:0051252 391 0.013
response to vitamin GO:0033273 131 0.013
response to radiation GO:0009314 137 0.013
rhythmic process GO:0048511 156 0.013
positive regulation of multicellular organismal process GO:0051240 387 0.013
amine metabolic process GO:0009308 38 0.013
regulation of canonical wnt signaling pathway GO:0060828 4 0.013
positive regulation of molecular function GO:0044093 230 0.013
Mouse
response to starvation GO:0042594 59 0.013
regulation of transmembrane transport GO:0034762 122 0.013
organophosphate biosynthetic process GO:0090407 143 0.012
neuron projection development GO:0031175 273 0.012
liver development GO:0001889 90 0.012
Mouse Rat
regulation of mapk cascade GO:0043408 116 0.012
Mouse
negative regulation of programmed cell death GO:0043069 183 0.012
positive regulation of humoral immune response GO:0002922 2 0.012
regulation of secretion by cell GO:1903530 208 0.012
glucose homeostasis GO:0042593 75 0.012
Rat
regeneration GO:0031099 163 0.012
regulation of muscle system process GO:0090257 79 0.012
eye morphogenesis GO:0048592 4 0.012
salivary gland development GO:0007431 3 0.012
Human Mouse
skeletal muscle tissue development GO:0007519 31 0.012
cell projection organization GO:0030030 302 0.012
single organism intracellular transport GO:1902582 166 0.012
response to estrogen GO:0043627 232 0.012
positive regulation of cell communication GO:0010647 271 0.012
Human Mouse
cgmp biosynthetic process GO:0006182 15 0.012
organic cyclic compound catabolic process GO:1901361 175 0.012
regulation of cellular catabolic process GO:0031329 101 0.012
nucleobase containing small molecule metabolic process GO:0055086 316 0.012
regulation of purine nucleotide biosynthetic process GO:1900371 46 0.012
epithelial cell differentiation GO:0030855 71 0.012
negative regulation of cellular protein metabolic process GO:0032269 106 0.012
Human
positive regulation of cellular component movement GO:0051272 102 0.012
Human Rat
ras protein signal transduction GO:0007265 29 0.012
sensory organ development GO:0007423 74 0.012
regulation of cellular response to stress GO:0080135 49 0.012
striated muscle contraction GO:0006941 44 0.012
cellular homeostasis GO:0019725 252 0.012
Rat
growth GO:0040007 165 0.012
Rat
receptor internalization GO:0031623 14 0.011
cellular response to alcohol GO:0097306 87 0.011
Rat
regulation of b cell mediated immunity GO:0002712 2 0.011
regulation of calcium ion transport GO:0051924 77 0.011
prostate gland morphogenesis GO:0060512 2 0.011
positive regulation of locomotion GO:0040017 102 0.011
Human Rat
regulation of hormone levels GO:0010817 187 0.011
negative regulation of cellular metabolic process GO:0031324 281 0.011
Human
regulation of isotype switching to igg isotypes GO:0048302 1 0.011
purine containing compound metabolic process GO:0072521 253 0.011
response to ketone GO:1901654 182 0.011
Rat
response to ammonium ion GO:0060359 71 0.011
Rat
regulation of reactive oxygen species metabolic process GO:2000377 26 0.011
Rat
negative regulation of phosphorus metabolic process GO:0010563 80 0.011
cellular process involved in reproduction in multicellular organism GO:0022412 35 0.011
regulation of transporter activity GO:0032409 50 0.011
positive regulation of apoptotic process GO:0043065 154 0.011
regulation of protein phosphorylation GO:0001932 183 0.011
Human Mouse
regulation of nucleotide metabolic process GO:0006140 117 0.011
anterior posterior pattern specification GO:0009952 1 0.011
t cell homeostasis GO:0043029 2 0.011
signal transduction by phosphorylation GO:0023014 144 0.011
Mouse
single organism carbohydrate metabolic process GO:0044723 118 0.011
purine ribonucleoside catabolic process GO:0046130 124 0.011
positive regulation of reactive oxygen species metabolic process GO:2000379 16 0.011
Rat
b cell mediated immunity GO:0019724 4 0.011
regulation of cytoskeleton organization GO:0051493 49 0.011
response to activity GO:0014823 73 0.011
Rat
response to insulin GO:0032868 133 0.010
regulation of nucleotide biosynthetic process GO:0030808 47 0.010
cellular response to inorganic substance GO:0071241 65 0.010
regulation of ion transmembrane transport GO:0034765 121 0.010
biological adhesion GO:0022610 110 0.010
organonitrogen compound catabolic process GO:1901565 179 0.010
regulation of immune response to tumor cell GO:0002837 3 0.010
central nervous system development GO:0007417 311 0.010
Zebrafish
platelet aggregation GO:0070527 4 0.010
positive regulation of transport GO:0051050 245 0.010
cation homeostasis GO:0055080 195 0.010
small molecule biosynthetic process GO:0044283 124 0.010
multicellular organismal homeostasis GO:0048871 49 0.010
regulation of actin filament based process GO:0032970 42 0.010
cellular response to carbohydrate stimulus GO:0071322 72 0.010
Rat
positive regulation of camp metabolic process GO:0030816 31 0.010
regulation of dendrite development GO:0050773 59 0.010
striated muscle tissue development GO:0014706 58 0.010
divalent metal ion transport GO:0070838 132 0.010

Hgf disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.026
disease of anatomical entity DOID:7 0 0.017
Human
cardiovascular system disease DOID:1287 0 0.017
cancer DOID:162 0 0.016
disease of cellular proliferation DOID:14566 0 0.016
musculoskeletal system disease DOID:17 0 0.013
artery disease DOID:0050828 0 0.011
vascular disease DOID:178 0 0.011