Rattus norvegicus

48 known processes

Pros1

protein S (alpha)

Pros1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cellular catabolic process GO:0044248 295 0.351
organic substance catabolic process GO:1901575 316 0.275
single organism catabolic process GO:0044712 283 0.241
response to inorganic substance GO:0010035 377 0.210
neurological system process GO:0050877 219 0.190
homeostatic process GO:0042592 331 0.176
cognition GO:0050890 92 0.157
response to nutrient levels GO:0031667 370 0.152
regulation of cellular component organization GO:0051128 368 0.144
tissue development GO:0009888 252 0.139
secretion by cell GO:0032940 248 0.137
aging GO:0007568 241 0.135
secretion GO:0046903 307 0.127
regulation of catalytic activity GO:0050790 304 0.121
positive regulation of molecular function GO:0044093 230 0.115
regulation of secretion by cell GO:1903530 208 0.114
oxoacid metabolic process GO:0043436 290 0.112
catabolic process GO:0009056 351 0.111
response to metal ion GO:0010038 253 0.109
response to extracellular stimulus GO:0009991 380 0.107
regulation of hydrolase activity GO:0051336 143 0.105
regulation of nervous system development GO:0051960 264 0.105
aromatic compound catabolic process GO:0019439 168 0.102
response to molecule of bacterial origin GO:0002237 194 0.102
response to lipopolysaccharide GO:0032496 191 0.101
response to corticosteroid GO:0031960 235 0.094
regulation of cellular protein metabolic process GO:0032268 267 0.093
learning or memory GO:0007611 90 0.093
response to external biotic stimulus GO:0043207 221 0.092
single organism carbohydrate metabolic process GO:0044723 118 0.091
lipid metabolic process GO:0006629 283 0.090
carbohydrate metabolic process GO:0005975 130 0.087
positive regulation of response to stimulus GO:0048584 285 0.086
positive regulation of cellular component organization GO:0051130 200 0.086
multicellular organism reproduction GO:0032504 233 0.085
apoptotic process GO:0006915 381 0.077
carboxylic acid metabolic process GO:0019752 289 0.077
response to bacterium GO:0009617 200 0.077
proteolysis GO:0006508 175 0.076
response to cobalt ion GO:0032025 12 0.074
carbohydrate derivative metabolic process GO:1901135 346 0.073
response to glucocorticoid GO:0051384 223 0.071
behavior GO:0007610 205 0.070
positive regulation of secretion GO:0051047 140 0.070
response to nutrient GO:0007584 248 0.069
defense response GO:0006952 194 0.068
cellular homeostasis GO:0019725 252 0.068
regulation of molecular function GO:0065009 398 0.068
regulation of multicellular organismal development GO:2000026 376 0.067
regulation of phosphate metabolic process GO:0019220 349 0.066
positive regulation of cell communication GO:0010647 271 0.065
inflammatory response GO:0006954 150 0.065
negative regulation of programmed cell death GO:0043069 183 0.065
regulation of hormone levels GO:0010817 187 0.063
neuron projection development GO:0031175 273 0.063
heterocycle catabolic process GO:0046700 167 0.062
organophosphate metabolic process GO:0019637 370 0.062
regulation of protein metabolic process GO:0051246 289 0.062
nucleobase containing small molecule metabolic process GO:0055086 316 0.061
regulation of cell development GO:0060284 263 0.061
multicellular organismal reproductive process GO:0048609 233 0.060
response to transition metal nanoparticle GO:1990267 122 0.059
regulation of cell differentiation GO:0045595 320 0.059
anatomical structure morphogenesis GO:0009653 298 0.058
chemical homeostasis GO:0048878 292 0.056
monosaccharide metabolic process GO:0005996 61 0.055
regulation of cellular localization GO:0060341 263 0.051
intracellular signal transduction GO:0035556 314 0.050
regulation of secretion GO:0051046 224 0.050
coumarin catabolic process GO:0046226 3 0.049
positive regulation of secretion by cell GO:1903532 128 0.049
g protein coupled receptor signaling pathway GO:0007186 242 0.049
negative regulation of cell death GO:0060548 229 0.049
organic cyclic compound catabolic process GO:1901361 175 0.048
growth GO:0040007 165 0.048
organonitrogen compound biosynthetic process GO:1901566 167 0.048
regulation of neuron differentiation GO:0045664 208 0.048
organic acid metabolic process GO:0006082 292 0.048
rna biosynthetic process GO:0032774 380 0.047
positive regulation of signaling GO:0023056 270 0.047
response to ethanol GO:0045471 162 0.047
programmed cell death GO:0012501 392 0.046
positive regulation of cell death GO:0010942 184 0.045
tube development GO:0035295 89 0.045
response to acid chemical GO:0001101 222 0.044
neuron death GO:0070997 127 0.044
neuron development GO:0048666 286 0.044
immune system process GO:0002376 204 0.043
peptidyl amino acid modification GO:0018193 126 0.043
immune response GO:0006955 104 0.043
response to alkaloid GO:0043279 132 0.043
regulation of cell proliferation GO:0042127 359 0.043
regulation of apoptotic process GO:0042981 335 0.043
cellular response to acid chemical GO:0071229 75 0.042
response to biotic stimulus GO:0009607 226 0.042
signal transduction by phosphorylation GO:0023014 144 0.041
regulation of signal transduction GO:0009966 318 0.041
organonitrogen compound catabolic process GO:1901565 179 0.041
regulation of ion transport GO:0043269 245 0.041
cellular response to external stimulus GO:0071496 118 0.040
regulation of neuron projection development GO:0010975 161 0.040
cellular response to lipid GO:0071396 201 0.039
negative regulation of metabolic process GO:0009892 331 0.038
positive regulation of cellular protein metabolic process GO:0032270 167 0.038
gland development GO:0048732 155 0.038
regulation of neurogenesis GO:0050767 247 0.037
glycosyl compound catabolic process GO:1901658 126 0.037
regulation of programmed cell death GO:0043067 341 0.037
cation transport GO:0006812 382 0.036
neuron differentiation GO:0030182 368 0.036
metal ion transport GO:0030001 289 0.036
cellular amino acid metabolic process GO:0006520 107 0.035
single organism biosynthetic process GO:0044711 342 0.034
positive regulation of transport GO:0051050 245 0.034
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.034
cell projection organization GO:0030030 302 0.033
negative regulation of signaling GO:0023057 157 0.033
reproductive process GO:0022414 372 0.033
positive regulation of neuron differentiation GO:0045666 126 0.033
divalent inorganic cation homeostasis GO:0072507 165 0.032
response to estradiol GO:0032355 164 0.032
single organism reproductive process GO:0044702 297 0.032
locomotion GO:0040011 237 0.032
rna metabolic process GO:0016070 406 0.032
localization of cell GO:0051674 202 0.032
response to camp GO:0051591 91 0.032
enzyme linked receptor protein signaling pathway GO:0007167 116 0.032
positive regulation of catalytic activity GO:0043085 184 0.032
development of primary sexual characteristics GO:0045137 107 0.032
response to amino acid GO:0043200 75 0.031
regulation of cell projection organization GO:0031344 175 0.031
multi organism reproductive process GO:0044703 262 0.031
cellular response to oxygen containing compound GO:1901701 386 0.031
cellular response to organonitrogen compound GO:0071417 197 0.030
negative regulation of protein metabolic process GO:0051248 114 0.030
positive regulation of programmed cell death GO:0043068 157 0.030
positive regulation of nervous system development GO:0051962 178 0.030
phenylpropanoid catabolic process GO:0046271 3 0.030
response to wounding GO:0009611 254 0.030
regulation of phosphorus metabolic process GO:0051174 349 0.029
nucleic acid templated transcription GO:0097659 379 0.029
reproductive system development GO:0061458 128 0.029
negative regulation of apoptotic process GO:0043066 181 0.029
signal release GO:0023061 145 0.029
eye morphogenesis GO:0048592 4 0.028
positive regulation of developmental process GO:0051094 283 0.028
positive regulation of phosphorus metabolic process GO:0010562 262 0.027
cellular response to peptide GO:1901653 133 0.027
regulation of neuron death GO:1901214 115 0.027
response to other organism GO:0051707 220 0.027
axon development GO:0061564 96 0.027
response to estrogen GO:0043627 232 0.027
insulin like growth factor receptor signaling pathway GO:0048009 3 0.026
positive regulation of cytokine secretion GO:0050715 9 0.026
carbohydrate derivative catabolic process GO:1901136 147 0.026
purine nucleotide metabolic process GO:0006163 229 0.026
purine containing compound metabolic process GO:0072521 253 0.026
regulation of rna metabolic process GO:0051252 391 0.026
positive regulation of phosphate metabolic process GO:0045937 262 0.026
response to ketone GO:1901654 182 0.026
cellular response to hormone stimulus GO:0032870 247 0.025
positive regulation of protein metabolic process GO:0051247 178 0.025
cellular component assembly GO:0022607 360 0.025
positive regulation of neurogenesis GO:0050769 165 0.025
protein maturation GO:0051604 68 0.025
negative regulation of response to stimulus GO:0048585 155 0.024
gonad development GO:0008406 104 0.024
positive regulation of cell projection organization GO:0031346 111 0.024
response to organophosphorus GO:0046683 102 0.024
response to purine containing compound GO:0014074 126 0.024
memory GO:0007613 54 0.024
negative regulation of signal transduction GO:0009968 83 0.024
organelle organization GO:0006996 266 0.024
cellular chemical homeostasis GO:0055082 247 0.024
regulation of growth GO:0040008 105 0.024
regulation of locomotion GO:0040012 148 0.024
single organism intracellular transport GO:1902582 166 0.023
negative regulation of multicellular organismal process GO:0051241 203 0.023
eye development GO:0001654 50 0.023
cellular amide metabolic process GO:0043603 44 0.023
negative regulation of macromolecule metabolic process GO:0010605 260 0.023
positive regulation of hydrolase activity GO:0051345 86 0.023
synaptic transmission GO:0007268 235 0.023
regulation of cellular catabolic process GO:0031329 101 0.023
cellular calcium ion homeostasis GO:0006874 160 0.022
response to peptide hormone GO:0043434 278 0.022
positive regulation of signal transduction GO:0009967 175 0.022
cellular response to endogenous stimulus GO:0071495 377 0.022
anion transport GO:0006820 178 0.022
positive regulation of biosynthetic process GO:0009891 319 0.022
macromolecule catabolic process GO:0009057 58 0.022
positive regulation of multicellular organismal process GO:0051240 387 0.022
positive regulation of cell development GO:0010720 176 0.022
positive regulation of cell proliferation GO:0008284 249 0.022
sex differentiation GO:0007548 113 0.022
feeding behavior GO:0007631 53 0.022
single organism organelle organization GO:1902589 180 0.022
organ morphogenesis GO:0009887 75 0.021
protein processing GO:0016485 68 0.021
positive regulation of immune system process GO:0002684 90 0.021
purine ribonucleotide metabolic process GO:0009150 227 0.021
small molecule catabolic process GO:0044282 59 0.021
calcium ion homeostasis GO:0055074 162 0.021
regulation of intracellular signal transduction GO:1902531 218 0.021
positive regulation of neuron projection development GO:0010976 99 0.021
negative regulation of cell communication GO:0010648 158 0.021
hormone secretion GO:0046879 115 0.021
heart morphogenesis GO:0003007 3 0.021
cell migration GO:0016477 197 0.021
cellular response to organic cyclic compound GO:0071407 202 0.021
respiratory system development GO:0060541 45 0.021
cellular modified amino acid metabolic process GO:0006575 61 0.020
cellular metal ion homeostasis GO:0006875 172 0.020
positive regulation of cellular biosynthetic process GO:0031328 295 0.020
cation homeostasis GO:0055080 195 0.020
single organism behavior GO:0044708 130 0.020
ribose phosphate metabolic process GO:0019693 235 0.020
regulation of peptide hormone secretion GO:0090276 80 0.020
mapk cascade GO:0000165 140 0.020
response to hexose GO:0009746 144 0.020
metal ion homeostasis GO:0055065 186 0.020
positive regulation of apoptotic process GO:0043065 154 0.020
positive regulation of cellular catabolic process GO:0031331 71 0.020
nucleoside metabolic process GO:0009116 179 0.020
reproduction GO:0000003 245 0.020
regulation of nucleic acid templated transcription GO:1903506 380 0.020
positive regulation of protein modification process GO:0031401 142 0.019
cellular lipid metabolic process GO:0044255 208 0.019
negative regulation of developmental process GO:0051093 125 0.019
positive regulation of cellular amine metabolic process GO:0033240 3 0.019
cell type specific apoptotic process GO:0097285 134 0.019
positive regulation of cell differentiation GO:0045597 217 0.019
response to glucose GO:0009749 136 0.019
monocarboxylic acid metabolic process GO:0032787 152 0.019
nucleobase containing compound catabolic process GO:0034655 152 0.019
nitrogen compound transport GO:0071705 229 0.019
regulation of peptide transport GO:0090087 87 0.019
regulation of proteolysis GO:0030162 66 0.019
response to peptide GO:1901652 292 0.019
macromolecule localization GO:0033036 252 0.018
small gtpase mediated signal transduction GO:0007264 36 0.018
cellular component movement GO:0006928 248 0.018
positive regulation of homeostatic process GO:0032846 49 0.018
response to fatty acid GO:0070542 65 0.018
response to vitamin GO:0033273 131 0.018
positive regulation of nucleic acid templated transcription GO:1903508 197 0.018
sexual reproduction GO:0019953 148 0.018
cell cell signaling GO:0007267 335 0.018
regulation of fat cell differentiation GO:0045598 3 0.018
rhythmic process GO:0048511 156 0.018
ribonucleoside metabolic process GO:0009119 174 0.018
nucleoside phosphate metabolic process GO:0006753 283 0.018
transcription dna templated GO:0006351 377 0.018
ribonucleotide metabolic process GO:0009259 231 0.018
regulation of rna biosynthetic process GO:2001141 381 0.018
negative regulation of gene expression GO:0010629 199 0.018
male gamete generation GO:0048232 99 0.017
regulation of vesicle mediated transport GO:0060627 81 0.017
hormone transport GO:0009914 121 0.017
response to hypoxia GO:0001666 231 0.017
organophosphate catabolic process GO:0046434 148 0.017
ovulation cycle GO:0042698 67 0.017
purine nucleoside metabolic process GO:0042278 169 0.017
cellular response to alcohol GO:0097306 87 0.017
sensory perception GO:0007600 101 0.017
negative regulation of phosphate metabolic process GO:0045936 80 0.017
sequestering of metal ion GO:0051238 9 0.017
regulation of peptidase activity GO:0052547 55 0.017
head development GO:0060322 247 0.017
negative regulation of cellular metabolic process GO:0031324 281 0.017
organic acid transport GO:0015849 116 0.017
protein phosphorylation GO:0006468 345 0.016
cellular ketone metabolic process GO:0042180 51 0.016
renal response to blood flow involved in circulatory renin angiotensin regulation of systemic arterial blood pressure GO:0001999 1 0.016
carbohydrate derivative biosynthetic process GO:1901137 124 0.016
regulation of bmp signaling pathway GO:0030510 2 0.016
positive regulation of transferase activity GO:0051347 81 0.016
peptide metabolic process GO:0006518 32 0.016
regulation of cell migration GO:0030334 128 0.016
nucleoside triphosphate catabolic process GO:0009143 123 0.016
response to cytokine GO:0034097 215 0.016
cellular response to hexose stimulus GO:0071331 65 0.016
transmission of nerve impulse GO:0019226 42 0.016
lung development GO:0030324 43 0.016
cardiovascular system development GO:0072358 134 0.016
negative regulation of molecular function GO:0044092 133 0.016
cell motility GO:0048870 202 0.016
response to toxic substance GO:0009636 133 0.016
positive regulation of phosphorylation GO:0042327 177 0.016
negative regulation of cell proliferation GO:0008285 119 0.016
cytokine production GO:0001816 61 0.015
response to retinoic acid GO:0032526 63 0.015
response to nicotine GO:0035094 51 0.015
regulation of cellular amine metabolic process GO:0033238 8 0.015
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.015
benzene containing compound metabolic process GO:0042537 22 0.015
positive regulation of protein transport GO:0051222 41 0.015
developmental growth GO:0048589 100 0.015
circulatory system development GO:0072359 134 0.015
divalent metal ion transport GO:0070838 132 0.015
cellular divalent inorganic cation homeostasis GO:0072503 162 0.015
cellular response to peptide hormone stimulus GO:0071375 120 0.015
amine metabolic process GO:0009308 38 0.015
regulation of phosphorylation GO:0042325 248 0.015
cellular cation homeostasis GO:0030003 180 0.014
peptide secretion GO:0002790 86 0.014
purine ribonucleoside catabolic process GO:0046130 124 0.014
cell growth GO:0016049 104 0.014
cellular ion homeostasis GO:0006873 184 0.014
digestive system development GO:0055123 41 0.014
positive regulation of cellular component movement GO:0051272 102 0.014
sensory organ development GO:0007423 74 0.014
purine nucleotide catabolic process GO:0006195 136 0.014
generation of precursor metabolites and energy GO:0006091 62 0.014
cytoplasmic transport GO:0016482 115 0.014
developmental process involved in reproduction GO:0003006 159 0.014
embryonic pattern specification GO:0009880 1 0.014
spermatogenesis GO:0007283 99 0.014
vasculature development GO:0001944 70 0.014
nucleoside phosphate catabolic process GO:1901292 140 0.014
hexose metabolic process GO:0019318 58 0.014
vesicle mediated transport GO:0016192 181 0.014
epithelium development GO:0060429 96 0.014
intracellular transport GO:0046907 185 0.014
protein complex assembly GO:0006461 263 0.014
regulation of cellular ketone metabolic process GO:0010565 27 0.014
mitotic sister chromatid separation GO:0051306 1 0.014
cellular response to molecule of bacterial origin GO:0071219 56 0.014
positive regulation of protein kinase activity GO:0045860 73 0.014
regulation of body fluid levels GO:0050878 90 0.014
brain development GO:0007420 247 0.013
positive regulation of catabolic process GO:0009896 78 0.013
regulation of synaptic transmission GO:0050804 141 0.013
regulation of peptide secretion GO:0002791 82 0.013
ion homeostasis GO:0050801 212 0.013
regulation of immune system process GO:0002682 123 0.013
purine containing compound catabolic process GO:0072523 138 0.013
multicellular organismal homeostasis GO:0048871 49 0.013
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.013
wound healing GO:0042060 122 0.013
nucleotide metabolic process GO:0009117 279 0.013
cellular amine metabolic process GO:0044106 38 0.013
cellular nitrogen compound catabolic process GO:0044270 163 0.013
cytokine secretion GO:0050663 15 0.013
exocytosis GO:0006887 60 0.013
cellular component biogenesis GO:0044085 368 0.013
ribose phosphate biosynthetic process GO:0046390 87 0.013
organic acid catabolic process GO:0016054 49 0.013
negative regulation of neuron death GO:1901215 69 0.013
neuron apoptotic process GO:0051402 88 0.013
negative regulation of phosphorus metabolic process GO:0010563 80 0.013
regulation of establishment of protein localization GO:0070201 69 0.013
calcium ion transport GO:0006816 131 0.013
cellular response to cytokine stimulus GO:0071345 127 0.012
acute inflammatory response GO:0002526 58 0.012
positive regulation of immune response GO:0050778 42 0.012
positive regulation of rna biosynthetic process GO:1902680 197 0.012
positive regulation of kinase activity GO:0033674 77 0.012
regulation of kinase activity GO:0043549 117 0.012
renin secretion into blood stream GO:0002001 1 0.012
immune effector process GO:0002252 53 0.012
ras protein signal transduction GO:0007265 29 0.012
gamete generation GO:0007276 124 0.012
response to carbohydrate GO:0009743 183 0.012
regulation of lipid metabolic process GO:0019216 68 0.012
regulation of response to external stimulus GO:0032101 106 0.012
regulation of protein localization GO:0032880 81 0.012
peptide transport GO:0015833 97 0.012
macromolecular complex subunit organization GO:0043933 339 0.012
protein complex biogenesis GO:0070271 263 0.012
peptide hormone secretion GO:0030072 84 0.011
luteolysis GO:0001554 5 0.011
regulation of protein modification process GO:0031399 194 0.011
negative regulation of cellular protein metabolic process GO:0032269 106 0.011
cellular response to metal ion GO:0071248 55 0.011
rho protein signal transduction GO:0007266 11 0.011
response to starvation GO:0042594 59 0.011
positive regulation of hemostasis GO:1900048 4 0.011
regulation of metal ion transport GO:0010959 118 0.011
respiratory tube development GO:0030323 43 0.011
ribonucleoside triphosphate metabolic process GO:0009199 141 0.011
glial cell differentiation GO:0010001 65 0.011
leukocyte mediated immunity GO:0002443 28 0.011
cardiac chamber development GO:0003205 1 0.011
positive regulation of lipid catabolic process GO:0050996 4 0.011
acute phase response GO:0006953 20 0.011
regulation of immune response GO:0050776 55 0.011
purine containing compound biosynthetic process GO:0072522 85 0.011
response to oxidative stress GO:0006979 186 0.011
ossification GO:0001503 70 0.011
anatomical structure formation involved in morphogenesis GO:0048646 83 0.011
cellular response to steroid hormone stimulus GO:0071383 93 0.011
protein localization GO:0008104 191 0.011
cellular response to insulin stimulus GO:0032869 81 0.011
ribonucleotide catabolic process GO:0009261 136 0.011
regulation of catabolic process GO:0009894 113 0.011
regulation of hormone secretion GO:0046883 106 0.011
peptide biosynthetic process GO:0043043 3 0.011
activation of cysteine type endopeptidase activity GO:0097202 4 0.011
ribonucleoside catabolic process GO:0042454 126 0.011
positive regulation of hormone secretion GO:0046887 65 0.011
heart development GO:0007507 72 0.011
regulation of transcription dna templated GO:0006355 374 0.011
liver development GO:0001889 90 0.011
female sex differentiation GO:0046660 59 0.010
positive regulation of transcription dna templated GO:0045893 197 0.010
amide transport GO:0042886 105 0.010
carboxylic acid transport GO:0046942 115 0.010
innate immune response GO:0045087 35 0.010
leukocyte activation GO:0045321 76 0.010
negative regulation of protein processing GO:0010955 47 0.010
lipid biosynthetic process GO:0008610 128 0.010
energy derivation by oxidation of organic compounds GO:0015980 46 0.010
reproductive structure development GO:0048608 128 0.010
positive regulation of gene expression GO:0010628 244 0.010
response to tumor necrosis factor GO:0034612 56 0.010
regulation of cell growth GO:0001558 85 0.010
ion transmembrane transport GO:0034220 365 0.010

Pros1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.055
inherited metabolic disorder DOID:655 0 0.046
disease of anatomical entity DOID:7 0 0.029
nervous system disease DOID:863 0 0.029
gastrointestinal system disease DOID:77 0 0.027
integumentary system disease DOID:16 0 0.017
sensory system disease DOID:0050155 0 0.012
eye and adnexa disease DOID:1492 0 0.012
eye disease DOID:5614 0 0.012