Rattus norvegicus

0 known processes

Psme1

proteasome (prosome, macropain) activator subunit 1

Psme1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
oxoacid metabolic process GO:0043436 290 0.308
cellular amino acid metabolic process GO:0006520 107 0.234
response to wounding GO:0009611 254 0.154
organic acid metabolic process GO:0006082 292 0.152
regulation of programmed cell death GO:0043067 341 0.137
cellular catabolic process GO:0044248 295 0.127
macromolecular complex subunit organization GO:0043933 339 0.126
carboxylic acid metabolic process GO:0019752 289 0.126
cellular response to stress GO:0033554 269 0.114
programmed cell death GO:0012501 392 0.107
catabolic process GO:0009056 351 0.104
immune system process GO:0002376 204 0.104
single organism biosynthetic process GO:0044711 342 0.099
response to nutrient levels GO:0031667 370 0.094
positive regulation of response to stimulus GO:0048584 285 0.086
macromolecular complex assembly GO:0065003 273 0.085
regulation of phosphate metabolic process GO:0019220 349 0.082
response to oxidative stress GO:0006979 186 0.077
protein complex subunit organization GO:0071822 302 0.072
oxidation reduction process GO:0055114 304 0.072
regulation of protein phosphorylation GO:0001932 183 0.072
response to metal ion GO:0010038 253 0.071
response to other organism GO:0051707 220 0.069
protein complex biogenesis GO:0070271 263 0.067
apoptotic process GO:0006915 381 0.066
protein phosphorylation GO:0006468 345 0.066
rna biosynthetic process GO:0032774 380 0.066
defense response GO:0006952 194 0.059
regulation of apoptotic process GO:0042981 335 0.058
proteolysis GO:0006508 175 0.056
response to inorganic substance GO:0010035 377 0.055
positive regulation of phosphorylation GO:0042327 177 0.053
neuron apoptotic process GO:0051402 88 0.052
cellular response to oxygen containing compound GO:1901701 386 0.052
regulation of cellular amino acid metabolic process GO:0006521 2 0.049
cellular amine metabolic process GO:0044106 38 0.049
amine metabolic process GO:0009308 38 0.048
response to biotic stimulus GO:0009607 226 0.047
negative regulation of apoptotic process GO:0043066 181 0.046
positive regulation of catalytic activity GO:0043085 184 0.046
regulation of transferase activity GO:0051338 123 0.046
positive regulation of cell proliferation GO:0008284 249 0.045
cellular component assembly GO:0022607 360 0.045
regulation of phosphorylation GO:0042325 248 0.044
regulation of molecular function GO:0065009 398 0.044
positive regulation of protein metabolic process GO:0051247 178 0.043
intracellular signal transduction GO:0035556 314 0.043
regulation of cell proliferation GO:0042127 359 0.043
positive regulation of developmental process GO:0051094 283 0.043
negative regulation of programmed cell death GO:0043069 183 0.042
regulation of signal transduction GO:0009966 318 0.041
regulation of neuron apoptotic process GO:0043523 83 0.041
lipid metabolic process GO:0006629 283 0.041
nucleobase containing small molecule metabolic process GO:0055086 316 0.040
positive regulation of multicellular organismal process GO:0051240 387 0.040
positive regulation of cell communication GO:0010647 271 0.039
intracellular protein transport GO:0006886 79 0.039
positive regulation of immune system process GO:0002684 90 0.038
cellular lipid metabolic process GO:0044255 208 0.038
positive regulation of signaling GO:0023056 270 0.038
positive regulation of cellular protein metabolic process GO:0032270 167 0.038
secretion GO:0046903 307 0.037
organic acid biosynthetic process GO:0016053 83 0.037
protein complex assembly GO:0006461 263 0.037
positive regulation of protein phosphorylation GO:0001934 135 0.037
homeostatic process GO:0042592 331 0.037
multicellular organismal reproductive process GO:0048609 233 0.037
cellular component biogenesis GO:0044085 368 0.036
reproductive process GO:0022414 372 0.036
regulation of protein modification process GO:0031399 194 0.036
response to extracellular stimulus GO:0009991 380 0.035
positive regulation of gene expression GO:0010628 244 0.035
cellular ketone metabolic process GO:0042180 51 0.035
positive regulation of programmed cell death GO:0043068 157 0.034
single organism reproductive process GO:0044702 297 0.034
regulation of nucleic acid templated transcription GO:1903506 380 0.034
regulation of transcription dna templated GO:0006355 374 0.034
response to peptide GO:1901652 292 0.034
immune response GO:0006955 104 0.033
protein oligomerization GO:0051259 191 0.033
regulation of secretion by cell GO:1903530 208 0.033
regulation of phosphorus metabolic process GO:0051174 349 0.033
regulation of cellular protein metabolic process GO:0032268 267 0.033
organic substance catabolic process GO:1901575 316 0.033
regulation of intracellular signal transduction GO:1902531 218 0.033
gamete generation GO:0007276 124 0.032
cation homeostasis GO:0055080 195 0.032
response to hydrogen peroxide GO:0042542 89 0.031
positive regulation of cellular biosynthetic process GO:0031328 295 0.031
multicellular organism reproduction GO:0032504 233 0.031
negative regulation of cell death GO:0060548 229 0.031
urogenital system development GO:0001655 78 0.031
regulation of cell development GO:0060284 263 0.030
chemical homeostasis GO:0048878 292 0.030
anatomical structure morphogenesis GO:0009653 298 0.030
regulation of protein kinase activity GO:0045859 105 0.030
nitrogen compound transport GO:0071705 229 0.030
regulation of cellular amine metabolic process GO:0033238 8 0.030
regulation of cellular ketone metabolic process GO:0010565 27 0.029
response to bacterium GO:0009617 200 0.029
single organism catabolic process GO:0044712 283 0.028
response to transition metal nanoparticle GO:1990267 122 0.028
response to alkaloid GO:0043279 132 0.028
regulation of secretion GO:0051046 224 0.028
multicellular organism growth GO:0035264 1 0.028
response to estradiol GO:0032355 164 0.027
cellular modified amino acid metabolic process GO:0006575 61 0.027
positive regulation of protein modification process GO:0031401 142 0.027
head development GO:0060322 247 0.027
positive regulation of cell death GO:0010942 184 0.027
aging GO:0007568 241 0.027
response to toxic substance GO:0009636 133 0.027
response to peptide hormone GO:0043434 278 0.026
positive regulation of transferase activity GO:0051347 81 0.026
regulation of response to wounding GO:1903034 69 0.026
cellular response to organic cyclic compound GO:0071407 202 0.026
organophosphate metabolic process GO:0019637 370 0.026
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.026
positive regulation of phosphorus metabolic process GO:0010562 262 0.025
response to reactive oxygen species GO:0000302 120 0.025
reproduction GO:0000003 245 0.025
lipid biosynthetic process GO:0008610 128 0.025
single organism intracellular transport GO:1902582 166 0.025
response to organophosphorus GO:0046683 102 0.025
regulation of kinase activity GO:0043549 117 0.025
neuron development GO:0048666 286 0.025
rna metabolic process GO:0016070 406 0.025
cellular homeostasis GO:0019725 252 0.025
regulation of rna metabolic process GO:0051252 391 0.024
regulation of catalytic activity GO:0050790 304 0.024
cellular chemical homeostasis GO:0055082 247 0.024
ion homeostasis GO:0050801 212 0.024
organelle organization GO:0006996 266 0.024
cell morphogenesis GO:0000902 142 0.024
positive regulation of molecular function GO:0044093 230 0.024
sulfur compound metabolic process GO:0006790 70 0.024
ion transmembrane transport GO:0034220 365 0.024
response to corticosteroid GO:0031960 235 0.024
cellular component morphogenesis GO:0032989 155 0.024
metal ion homeostasis GO:0055065 186 0.023
cell type specific apoptotic process GO:0097285 134 0.023
nucleoside phosphate metabolic process GO:0006753 283 0.023
signal transduction by phosphorylation GO:0023014 144 0.023
response to external biotic stimulus GO:0043207 221 0.023
regulation of protein metabolic process GO:0051246 289 0.023
peptide metabolic process GO:0006518 32 0.023
sexual reproduction GO:0019953 148 0.023
cell activation GO:0001775 97 0.023
inflammatory response GO:0006954 150 0.023
transcription dna templated GO:0006351 377 0.022
regulation of neuron death GO:1901214 115 0.022
positive regulation of cellular amine metabolic process GO:0033240 3 0.022
cellular response to hormone stimulus GO:0032870 247 0.022
negative regulation of metabolic process GO:0009892 331 0.022
purine nucleoside metabolic process GO:0042278 169 0.022
carboxylic acid biosynthetic process GO:0046394 83 0.022
biological adhesion GO:0022610 110 0.022
mapk cascade GO:0000165 140 0.021
membrane organization GO:0061024 94 0.021
lymphocyte activation GO:0046649 43 0.021
t cell proliferation GO:0042098 19 0.021
amide transport GO:0042886 105 0.021
positive regulation of apoptotic process GO:0043065 154 0.021
leukocyte activation GO:0045321 76 0.021
regulation of response to stress GO:0080134 126 0.021
response to decreased oxygen levels GO:0036293 237 0.021
response to acid chemical GO:0001101 222 0.021
regulation of cell differentiation GO:0045595 320 0.021
purine ribonucleoside metabolic process GO:0046128 168 0.021
cellular response to lipid GO:0071396 201 0.021
cellular cation homeostasis GO:0030003 180 0.021
monocarboxylic acid metabolic process GO:0032787 152 0.021
localization of cell GO:0051674 202 0.020
regulation of body fluid levels GO:0050878 90 0.020
multi organism reproductive process GO:0044703 262 0.020
response to estrogen GO:0043627 232 0.020
response to purine containing compound GO:0014074 126 0.020
regulation of membrane potential GO:0042391 110 0.020
sensory organ development GO:0007423 74 0.020
response to monosaccharide GO:0034284 159 0.020
positive regulation of protein kinase activity GO:0045860 73 0.020
regulation of hormone levels GO:0010817 187 0.019
neuron projection development GO:0031175 273 0.019
gland development GO:0048732 155 0.019
cellular macromolecule catabolic process GO:0044265 29 0.019
regulation of mapk cascade GO:0043408 116 0.019
cellular ion homeostasis GO:0006873 184 0.019
response to glucocorticoid GO:0051384 223 0.018
cellular amide metabolic process GO:0043603 44 0.018
regulation of anatomical structure size GO:0090066 135 0.018
mechanoreceptor differentiation GO:0042490 2 0.018
single organism membrane organization GO:0044802 74 0.018
cellular component movement GO:0006928 248 0.018
kidney development GO:0001822 67 0.018
nucleic acid templated transcription GO:0097659 379 0.018
positive regulation of phosphate metabolic process GO:0045937 262 0.018
brain development GO:0007420 247 0.018
positive regulation of mapk cascade GO:0043410 92 0.018
rhythmic process GO:0048511 156 0.018
positive regulation of kinase activity GO:0033674 77 0.017
anion transport GO:0006820 178 0.017
cell projection organization GO:0030030 302 0.017
negative regulation of neuron death GO:1901215 69 0.017
neuron death GO:0070997 127 0.017
nucleotide metabolic process GO:0009117 279 0.017
regulation of immune response GO:0050776 55 0.017
inorganic ion transmembrane transport GO:0098660 229 0.017
response to molecule of bacterial origin GO:0002237 194 0.017
renal system development GO:0072001 67 0.017
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.017
purine containing compound metabolic process GO:0072521 253 0.017
intracellular transport GO:0046907 185 0.017
response to ethanol GO:0045471 162 0.016
cellular response to organonitrogen compound GO:0071417 197 0.016
response to glucose GO:0009749 136 0.016
response to cytokine GO:0034097 215 0.016
cation transmembrane transport GO:0098655 263 0.016
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.016
cellular response to external stimulus GO:0071496 118 0.016
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.016
circadian rhythm GO:0007623 88 0.016
regulation of apoptotic signaling pathway GO:2001233 13 0.016
single organism organelle organization GO:1902589 180 0.016
locomotion GO:0040011 237 0.016
positive regulation of biosynthetic process GO:0009891 319 0.016
response to growth factor GO:0070848 189 0.016
regulation of multicellular organismal development GO:2000026 376 0.015
macromolecule localization GO:0033036 252 0.015
protection from natural killer cell mediated cytotoxicity GO:0042270 2 0.015
neuron differentiation GO:0030182 368 0.015
response to nicotine GO:0035094 51 0.015
transmembrane transport GO:0055085 412 0.015
negative regulation of neuron apoptotic process GO:0043524 45 0.015
response to radiation GO:0009314 137 0.015
regulation of neurogenesis GO:0050767 247 0.015
regeneration GO:0031099 163 0.015
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.015
negative regulation of biosynthetic process GO:0009890 168 0.015
positive regulation of protein serine threonine kinase activity GO:0071902 52 0.015
positive regulation of secretion by cell GO:1903532 128 0.015
negative regulation of natural killer cell mediated immunity GO:0002716 4 0.015
behavior GO:0007610 205 0.015
cation transport GO:0006812 382 0.015
regulation of response to external stimulus GO:0032101 106 0.014
blood circulation GO:0008015 183 0.014
spindle organization GO:0007051 2 0.014
transcription from rna polymerase ii promoter GO:0006366 252 0.014
cellular response to oxidative stress GO:0034599 76 0.014
nucleoside monophosphate metabolic process GO:0009123 93 0.014
cellular response to endogenous stimulus GO:0071495 377 0.014
fatty acid metabolic process GO:0006631 99 0.014
small molecule biosynthetic process GO:0044283 124 0.014
regulation of cellular localization GO:0060341 263 0.014
positive regulation of response to external stimulus GO:0032103 51 0.014
purine ribonucleotide metabolic process GO:0009150 227 0.014
axis specification GO:0009798 4 0.014
response to lipopolysaccharide GO:0032496 191 0.014
regulation of immune system process GO:0002682 123 0.014
neurological system process GO:0050877 219 0.014
regulation of defense response GO:0031347 68 0.014
regulation of rna biosynthetic process GO:2001141 381 0.014
male sex differentiation GO:0046661 64 0.014
peptide transport GO:0015833 97 0.013
organonitrogen compound biosynthetic process GO:1901566 167 0.013
carbohydrate derivative metabolic process GO:1901135 346 0.013
regulation of ion transmembrane transport GO:0034765 121 0.013
cellular response to metal ion GO:0071248 55 0.013
response to carbohydrate GO:0009743 183 0.013
positive regulation of signal transduction GO:0009967 175 0.013
response to oxygen levels GO:0070482 265 0.013
negative regulation of cellular biosynthetic process GO:0031327 161 0.013
cell cycle checkpoint GO:0000075 2 0.013
developmental process involved in reproduction GO:0003006 159 0.013
heterocycle catabolic process GO:0046700 167 0.013
fatty acid derivative biosynthetic process GO:1901570 18 0.013
cytokine production GO:0001816 61 0.013
peptidyl tyrosine phosphorylation GO:0018108 72 0.013
immune effector process GO:0002252 53 0.013
metal ion transport GO:0030001 289 0.013
glycosyl compound metabolic process GO:1901657 182 0.013
protein homooligomerization GO:0051260 91 0.013
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.013
organ regeneration GO:0031100 101 0.012
positive regulation of neurogenesis GO:0050769 165 0.012
secretion by cell GO:0032940 248 0.012
cellular response to abiotic stimulus GO:0071214 85 0.012
nucleotide biosynthetic process GO:0009165 98 0.012
reactive oxygen species metabolic process GO:0072593 37 0.012
cellular metal ion homeostasis GO:0006875 172 0.012
apoptotic signaling pathway GO:0097190 27 0.012
circulatory system process GO:0003013 183 0.012
forebrain development GO:0030900 98 0.012
response to ketone GO:1901654 182 0.012
response to dexamethasone GO:0071548 49 0.012
negative regulation of macromolecule metabolic process GO:0010605 260 0.012
positive regulation of secretion GO:0051047 140 0.012
multi multicellular organism process GO:0044706 138 0.012
central nervous system development GO:0007417 311 0.012
response to vitamin GO:0033273 131 0.012
positive regulation of defense response GO:0031349 37 0.011
telencephalon development GO:0021537 62 0.011
cytoskeleton organization GO:0007010 111 0.011
regulation of peptide secretion GO:0002791 82 0.011
unsaturated fatty acid metabolic process GO:0033559 39 0.011
regulation of cell morphogenesis GO:0022604 77 0.011
cell migration GO:0016477 197 0.011
hair cell differentiation GO:0035315 2 0.011
signal release GO:0023061 145 0.011
response to nutrient GO:0007584 248 0.011
fatty acid derivative metabolic process GO:1901568 38 0.011
nucleoside metabolic process GO:0009116 179 0.011
response to axon injury GO:0048678 59 0.011
organic cyclic compound catabolic process GO:1901361 175 0.011
protein localization GO:0008104 191 0.011
synaptic transmission GO:0007268 235 0.011
cofactor metabolic process GO:0051186 95 0.011
spermatogenesis GO:0007283 99 0.011
cellular calcium ion homeostasis GO:0006874 160 0.011
purine ribonucleoside monophosphate metabolic process GO:0009167 84 0.011
reproductive system development GO:0061458 128 0.011
response to hexose GO:0009746 144 0.011
cellular response to cytokine stimulus GO:0071345 127 0.011
positive regulation of response to wounding GO:1903036 34 0.011
cell adhesion GO:0007155 110 0.010
purine nucleoside triphosphate metabolic process GO:0009144 141 0.010
monovalent inorganic cation transport GO:0015672 172 0.010
inner ear receptor cell differentiation GO:0060113 2 0.010
growth GO:0040007 165 0.010
ribonucleotide metabolic process GO:0009259 231 0.010
leukocyte migration GO:0050900 38 0.010
response to light stimulus GO:0009416 52 0.010
negative regulation of rna biosynthetic process GO:1902679 118 0.010
cellular response to reactive oxygen species GO:0034614 55 0.010
anterior posterior pattern specification GO:0009952 1 0.010
glucose homeostasis GO:0042593 75 0.010
regulation of cellular component organization GO:0051128 368 0.010
purine nucleoside catabolic process GO:0006152 124 0.010
cellular response to peptide GO:1901653 133 0.010
cellular protein localization GO:0034613 122 0.010
regulation of locomotion GO:0040012 148 0.010
cell motility GO:0048870 202 0.010
aromatic compound catabolic process GO:0019439 168 0.010
organ morphogenesis GO:0009887 75 0.010

Psme1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
cancer DOID:162 0 0.019
disease of cellular proliferation DOID:14566 0 0.019
organ system cancer DOID:0050686 0 0.019