Rattus norvegicus

82 known processes

Irak1

interleukin-1 receptor-associated kinase 1

(Aliases: RGD1563841)

Irak1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
oxoacid metabolic process GO:0043436 290 0.166
carboxylic acid metabolic process GO:0019752 289 0.131
organic acid metabolic process GO:0006082 292 0.123
single organism carbohydrate metabolic process GO:0044723 118 0.094
cellular response to oxygen containing compound GO:1901701 386 0.089
regulation of proteasomal protein catabolic process GO:0061136 4 0.070
carbohydrate metabolic process GO:0005975 130 0.067
cellular amino acid metabolic process GO:0006520 107 0.066
lipid metabolic process GO:0006629 283 0.053
single organism biosynthetic process GO:0044711 342 0.042
multicellular organism reproduction GO:0032504 233 0.040
reproductive process GO:0022414 372 0.037
response to peptide GO:1901652 292 0.037
response to extracellular stimulus GO:0009991 380 0.037
nucleic acid templated transcription GO:0097659 379 0.036
Human
response to nutrient levels GO:0031667 370 0.035
positive regulation of cellular biosynthetic process GO:0031328 295 0.035
multi organism reproductive process GO:0044703 262 0.033
rna biosynthetic process GO:0032774 380 0.033
Human
response to peptide hormone GO:0043434 278 0.033
secretion by cell GO:0032940 248 0.032
regulation of transcription dna templated GO:0006355 374 0.032
Human
cellular response to endogenous stimulus GO:0071495 377 0.032
negative regulation of macromolecule metabolic process GO:0010605 260 0.032
regulation of hormone levels GO:0010817 187 0.032
response to bacterium GO:0009617 200 0.032
cellular catabolic process GO:0044248 295 0.030
circulatory system development GO:0072359 134 0.030
carbohydrate derivative biosynthetic process GO:1901137 124 0.030
organic acid biosynthetic process GO:0016053 83 0.030
negative regulation of gene expression GO:0010629 199 0.030
intracellular signal transduction GO:0035556 314 0.029
cellular response to hormone stimulus GO:0032870 247 0.028
catabolic process GO:0009056 351 0.028
regulation of rna metabolic process GO:0051252 391 0.028
Human
positive regulation of cell death GO:0010942 184 0.028
response to corticosteroid GO:0031960 235 0.027
amine metabolic process GO:0009308 38 0.027
positive regulation of cell proliferation GO:0008284 249 0.027
monocarboxylic acid metabolic process GO:0032787 152 0.026
regulation of cellular amino acid metabolic process GO:0006521 2 0.026
cellular amine metabolic process GO:0044106 38 0.026
transcription from rna polymerase ii promoter GO:0006366 252 0.026
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.025
response to ketone GO:1901654 182 0.025
cellular response to growth factor stimulus GO:0071363 162 0.023
fatty acid metabolic process GO:0006631 99 0.023
response to acid chemical GO:0001101 222 0.023
regulation of cellular ketone metabolic process GO:0010565 27 0.023
secretion GO:0046903 307 0.023
regulation of signal transduction GO:0009966 318 0.022
Human
nucleotide metabolic process GO:0009117 279 0.022
cellular response to nitrogen compound GO:1901699 210 0.022
cellular lipid metabolic process GO:0044255 208 0.022
organic substance catabolic process GO:1901575 316 0.022
central nervous system development GO:0007417 311 0.022
cellular response to lipid GO:0071396 201 0.022
rna metabolic process GO:0016070 406 0.021
Human
peptidyl amino acid modification GO:0018193 126 0.021
signal release GO:0023061 145 0.021
single organism reproductive process GO:0044702 297 0.021
cardiovascular system development GO:0072358 134 0.021
positive regulation of signal transduction GO:0009967 175 0.021
Human
sulfur compound metabolic process GO:0006790 70 0.021
regulation of cellular amine metabolic process GO:0033238 8 0.020
regulation of nucleic acid templated transcription GO:1903506 380 0.020
Human
multicellular organismal reproductive process GO:0048609 233 0.020
response to nutrient GO:0007584 248 0.020
response to metal ion GO:0010038 253 0.020
cellular response to stress GO:0033554 269 0.020
cellular ketone metabolic process GO:0042180 51 0.020
positive regulation of rna metabolic process GO:0051254 203 0.019
transcription dna templated GO:0006351 377 0.019
Human
cellular response to peptide GO:1901653 133 0.019
response to glucocorticoid GO:0051384 223 0.019
reproduction GO:0000003 245 0.019
regulation of programmed cell death GO:0043067 341 0.018
multicellular organism growth GO:0035264 1 0.018
gamete generation GO:0007276 124 0.018
positive regulation of signaling GO:0023056 270 0.018
Human
cell cell signaling GO:0007267 335 0.018
cellular response to organonitrogen compound GO:0071417 197 0.018
heart morphogenesis GO:0003007 3 0.018
response to inorganic substance GO:0010035 377 0.017
positive regulation of molecular function GO:0044093 230 0.017
Human
positive regulation of nucleic acid templated transcription GO:1903508 197 0.017
response to estrogen GO:0043627 232 0.017
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.017
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.017
regulation of apoptotic process GO:0042981 335 0.016
negative regulation of metabolic process GO:0009892 331 0.016
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.016
homeostatic process GO:0042592 331 0.016
protein oligomerization GO:0051259 191 0.016
Human
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.016
positive regulation of biosynthetic process GO:0009891 319 0.016
response to growth factor GO:0070848 189 0.016
regulation of multicellular organismal development GO:2000026 376 0.016
programmed cell death GO:0012501 392 0.016
apoptotic process GO:0006915 381 0.016
regulation of cellular protein metabolic process GO:0032268 267 0.016
Human
heart development GO:0007507 72 0.015
regeneration GO:0031099 163 0.015
response to ethanol GO:0045471 162 0.015
nucleobase containing small molecule metabolic process GO:0055086 316 0.015
response to hypoxia GO:0001666 231 0.015
glycoprotein biosynthetic process GO:0009101 19 0.015
response to oxidative stress GO:0006979 186 0.015
positive regulation of cell differentiation GO:0045597 217 0.015
chemical homeostasis GO:0048878 292 0.015
positive regulation of cellular amine metabolic process GO:0033240 3 0.015
multi multicellular organism process GO:0044706 138 0.015
positive regulation of rna biosynthetic process GO:1902680 197 0.015
positive regulation of apoptotic process GO:0043065 154 0.014
carbohydrate derivative metabolic process GO:1901135 346 0.014
organic cyclic compound catabolic process GO:1901361 175 0.014
regulation of phosphorus metabolic process GO:0051174 349 0.014
Human
protein transport GO:0015031 132 0.014
anion transport GO:0006820 178 0.014
negative regulation of cell communication GO:0010648 158 0.014
monosaccharide metabolic process GO:0005996 61 0.014
proteolysis involved in cellular protein catabolic process GO:0051603 19 0.013
regulation of protein modification process GO:0031399 194 0.013
Human
nitrogen compound transport GO:0071705 229 0.013
ribose phosphate metabolic process GO:0019693 235 0.013
positive regulation of gene expression GO:0010628 244 0.013
nucleoside phosphate metabolic process GO:0006753 283 0.013
regulation of intracellular signal transduction GO:1902531 218 0.013
Human
positive regulation of phosphorus metabolic process GO:0010562 262 0.013
Human
cellular component assembly GO:0022607 360 0.013
Human
negative regulation of cellular metabolic process GO:0031324 281 0.013
positive regulation of transcription dna templated GO:0045893 197 0.013
coenzyme metabolic process GO:0006732 86 0.013
cell cycle GO:0007049 101 0.013
response to hexose GO:0009746 144 0.013
cellular carbohydrate metabolic process GO:0044262 72 0.013
regulation of protein metabolic process GO:0051246 289 0.013
Human
cell cycle checkpoint GO:0000075 2 0.013
aging GO:0007568 241 0.013
small molecule biosynthetic process GO:0044283 124 0.012
protein phosphorylation GO:0006468 345 0.012
small gtpase mediated signal transduction GO:0007264 36 0.012
positive regulation of response to stimulus GO:0048584 285 0.012
Human
lipid storage GO:0019915 1 0.012
cellular response to cytokine stimulus GO:0071345 127 0.012
regulation of molecular function GO:0065009 398 0.012
Human
regulation of cell differentiation GO:0045595 320 0.012
regulation of cell proliferation GO:0042127 359 0.012
single organism catabolic process GO:0044712 283 0.012
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.012
negative regulation of phosphorus metabolic process GO:0010563 80 0.012
positive regulation of phosphorylation GO:0042327 177 0.012
Human
cellular response to external stimulus GO:0071496 118 0.012
cellular chemical homeostasis GO:0055082 247 0.012
positive regulation of multicellular organismal process GO:0051240 387 0.012
nucleoside phosphate biosynthetic process GO:1901293 102 0.011
regulation of cell cycle GO:0051726 73 0.011
ion transmembrane transport GO:0034220 365 0.011
anatomical structure morphogenesis GO:0009653 298 0.011
protein complex assembly GO:0006461 263 0.011
Human
protein complex subunit organization GO:0071822 302 0.011
Human
behavior GO:0007610 205 0.011
organophosphate metabolic process GO:0019637 370 0.011
regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032434 3 0.011
locomotion GO:0040011 237 0.011
organ regeneration GO:0031100 101 0.011
regulation of rna biosynthetic process GO:2001141 381 0.011
Human
regulation of cell development GO:0060284 263 0.011
proteolysis GO:0006508 175 0.011
cation transport GO:0006812 382 0.011
negative regulation of mitotic cell cycle phase transition GO:1901991 3 0.011
dna metabolic process GO:0006259 96 0.011
response to monosaccharide GO:0034284 159 0.011
regulation of neurogenesis GO:0050767 247 0.011
response to insulin GO:0032868 133 0.011
response to lipopolysaccharide GO:0032496 191 0.011
negative regulation of protein metabolic process GO:0051248 114 0.011
organic anion transport GO:0015711 132 0.011
regulation of cellular component organization GO:0051128 368 0.011
response to cytokine GO:0034097 215 0.011
organonitrogen compound biosynthetic process GO:1901566 167 0.011
positive regulation of programmed cell death GO:0043068 157 0.011
negative regulation of cell cycle phase transition GO:1901988 4 0.011
cellular response to steroid hormone stimulus GO:0071383 93 0.010
negative regulation of phosphate metabolic process GO:0045936 80 0.010
positive regulation of developmental process GO:0051094 283 0.010
negative regulation of cellular protein metabolic process GO:0032269 106 0.010
response to estradiol GO:0032355 164 0.010
response to carbohydrate GO:0009743 183 0.010
cellular response to peptide hormone stimulus GO:0071375 120 0.010
response to glucose GO:0009749 136 0.010
defense response GO:0006952 194 0.010
Human
neuron development GO:0048666 286 0.010
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.010
enzyme linked receptor protein signaling pathway GO:0007167 116 0.010
neuron differentiation GO:0030182 368 0.010
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.010

Irak1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.028
inherited metabolic disorder DOID:655 0 0.024
disease of anatomical entity DOID:7 0 0.013
nervous system disease DOID:863 0 0.013