Rattus norvegicus

21 known processes

Aco1

aconitase 1, soluble

(Aliases: Acon1,Ratireb)

Aco1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
oxoacid metabolic process GO:0043436 290 0.750
Human
fatty acid oxidation GO:0019395 29 0.260
oxidation reduction process GO:0055114 304 0.210
carboxylic acid metabolic process GO:0019752 289 0.200
Human
organic acid metabolic process GO:0006082 292 0.194
Human
single organism catabolic process GO:0044712 283 0.174
response to nutrient levels GO:0031667 370 0.168
lipid metabolic process GO:0006629 283 0.162
organic substance catabolic process GO:1901575 316 0.149
protein complex subunit organization GO:0071822 302 0.142
fatty acid beta oxidation GO:0006635 22 0.119
organic acid transport GO:0015849 116 0.109
organophosphate metabolic process GO:0019637 370 0.098
monocarboxylic acid metabolic process GO:0032787 152 0.097
response to extracellular stimulus GO:0009991 380 0.095
behavior GO:0007610 205 0.094
carbohydrate derivative metabolic process GO:1901135 346 0.094
cellular component biogenesis GO:0044085 368 0.091
catabolic process GO:0009056 351 0.082
cellular catabolic process GO:0044248 295 0.077
response to nutrient GO:0007584 248 0.074
macromolecular complex assembly GO:0065003 273 0.070
organonitrogen compound biosynthetic process GO:1901566 167 0.070
single organism biosynthetic process GO:0044711 342 0.069
single organism carbohydrate metabolic process GO:0044723 118 0.069
protein complex biogenesis GO:0070271 263 0.064
lipid oxidation GO:0034440 30 0.064
fatty acid metabolic process GO:0006631 99 0.063
carboxylic acid catabolic process GO:0046395 49 0.062
nucleobase containing small molecule metabolic process GO:0055086 316 0.060
response to inorganic substance GO:0010035 377 0.059
Human Rat
nucleotide metabolic process GO:0009117 279 0.057
carboxylic acid transport GO:0046942 115 0.057
response to metal ion GO:0010038 253 0.057
Human Rat
cellular component assembly GO:0022607 360 0.057
anion transport GO:0006820 178 0.056
cellular response to endogenous stimulus GO:0071495 377 0.054
nitrogen compound transport GO:0071705 229 0.054
nucleoside phosphate metabolic process GO:0006753 283 0.053
regulation of cell differentiation GO:0045595 320 0.053
lipid catabolic process GO:0016042 46 0.050
macromolecular complex subunit organization GO:0043933 339 0.050
protein complex assembly GO:0006461 263 0.049
transmembrane transport GO:0055085 412 0.049
macromolecule localization GO:0033036 252 0.049
ion transmembrane transport GO:0034220 365 0.048
purine nucleotide metabolic process GO:0006163 229 0.048
regulation of nervous system development GO:0051960 264 0.047
ribonucleotide metabolic process GO:0009259 231 0.047
regulation of hormone levels GO:0010817 187 0.046
organic acid catabolic process GO:0016054 49 0.045
negative regulation of developmental process GO:0051093 125 0.045
ribose phosphate biosynthetic process GO:0046390 87 0.045
organophosphate biosynthetic process GO:0090407 143 0.044
cellular response to oxygen containing compound GO:1901701 386 0.043
carbohydrate metabolic process GO:0005975 130 0.043
monocarboxylic acid catabolic process GO:0072329 28 0.042
cell cell signaling GO:0007267 335 0.042
regulation of multicellular organismal development GO:2000026 376 0.042
ribose phosphate metabolic process GO:0019693 235 0.041
chemical homeostasis GO:0048878 292 0.041
neurological system process GO:0050877 219 0.040
sulfur compound metabolic process GO:0006790 70 0.039
intracellular signal transduction GO:0035556 314 0.039
carbohydrate derivative biosynthetic process GO:1901137 124 0.039
cellular ketone metabolic process GO:0042180 51 0.038
anatomical structure morphogenesis GO:0009653 298 0.038
Fly
neuron differentiation GO:0030182 368 0.038
purine containing compound metabolic process GO:0072521 253 0.038
cellular modified amino acid metabolic process GO:0006575 61 0.037
lipid modification GO:0030258 52 0.037
response to peptide GO:1901652 292 0.036
tissue development GO:0009888 252 0.036
carnitine metabolic process GO:0009437 3 0.036
secretion by cell GO:0032940 248 0.035
regulation of phosphorus metabolic process GO:0051174 349 0.035
gland development GO:0048732 155 0.035
cellular response to organonitrogen compound GO:0071417 197 0.035
nucleotide biosynthetic process GO:0009165 98 0.035
reproduction GO:0000003 245 0.034
small molecule catabolic process GO:0044282 59 0.034
negative regulation of multicellular organismal process GO:0051241 203 0.034
rhythmic process GO:0048511 156 0.034
regulation of cell development GO:0060284 263 0.033
cellular response to peptide hormone stimulus GO:0071375 120 0.033
cellular response to lipid GO:0071396 201 0.032
cellular response to hormone stimulus GO:0032870 247 0.032
purine ribonucleotide metabolic process GO:0009150 227 0.031
regulation of cellular localization GO:0060341 263 0.031
regulation of cellular component organization GO:0051128 368 0.031
carbohydrate catabolic process GO:0016052 40 0.031
regulation of cellular ketone metabolic process GO:0010565 27 0.030
regulation of establishment of planar polarity GO:0090175 2 0.030
regulation of neuron differentiation GO:0045664 208 0.030
regulation of signal transduction GO:0009966 318 0.030
positive regulation of cellular biosynthetic process GO:0031328 295 0.030
anion transmembrane transport GO:0098656 77 0.030
regulation of neurogenesis GO:0050767 247 0.030
regulation of phosphate metabolic process GO:0019220 349 0.029
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.029
positive regulation of phosphorus metabolic process GO:0010562 262 0.029
positive regulation of biosynthetic process GO:0009891 319 0.029
cellular response to nitrogen compound GO:1901699 210 0.029
central nervous system development GO:0007417 311 0.029
response to vitamin GO:0033273 131 0.029
nucleoside phosphate biosynthetic process GO:1901293 102 0.029
cellular lipid metabolic process GO:0044255 208 0.029
hepaticobiliary system development GO:0061008 90 0.029
positive regulation of multicellular organismal process GO:0051240 387 0.028
response to hypoxia GO:0001666 231 0.028
Rat
secretion GO:0046903 307 0.028
protein homooligomerization GO:0051260 91 0.028
epithelium development GO:0060429 96 0.028
multicellular organismal reproductive process GO:0048609 233 0.028
development of primary sexual characteristics GO:0045137 107 0.028
cellular amino acid metabolic process GO:0006520 107 0.027
regulation of cellular catabolic process GO:0031329 101 0.027
response to oxygen levels GO:0070482 265 0.027
Rat
organic anion transport GO:0015711 132 0.027
acetate ester biosynthetic process GO:1900620 2 0.026
monocarboxylic acid transport GO:0015718 52 0.026
response to acid chemical GO:0001101 222 0.026
Rat
positive regulation of fatty acid beta oxidation GO:0032000 4 0.026
ribonucleoside metabolic process GO:0009119 174 0.026
multicellular organism reproduction GO:0032504 233 0.026
response to peptide hormone GO:0043434 278 0.026
cation transport GO:0006812 382 0.025
cellular response to stress GO:0033554 269 0.025
Rat
positive regulation of molecular function GO:0044093 230 0.025
brain development GO:0007420 247 0.025
homeostatic process GO:0042592 331 0.024
cellular cation homeostasis GO:0030003 180 0.024
nucleoside metabolic process GO:0009116 179 0.024
g protein coupled receptor signaling pathway GO:0007186 242 0.024
organic cyclic compound catabolic process GO:1901361 175 0.024
inorganic ion transmembrane transport GO:0098660 229 0.024
single organism carbohydrate catabolic process GO:0044724 40 0.024
signal release GO:0023061 145 0.024
small molecule biosynthetic process GO:0044283 124 0.023
amide transport GO:0042886 105 0.023
response to ethanol GO:0045471 162 0.023
synaptic transmission GO:0007268 235 0.023
reproductive process GO:0022414 372 0.023
regulation of molecular function GO:0065009 398 0.023
positive regulation of phosphate metabolic process GO:0045937 262 0.023
regulation of neuron projection development GO:0010975 161 0.023
rna biosynthetic process GO:0032774 380 0.022
rna metabolic process GO:0016070 406 0.022
cellular amine metabolic process GO:0044106 38 0.022
apoptotic process GO:0006915 381 0.022
single organism behavior GO:0044708 130 0.022
ras protein signal transduction GO:0007265 29 0.022
positive regulation of developmental process GO:0051094 283 0.022
cell projection organization GO:0030030 302 0.022
lipid localization GO:0010876 62 0.022
amp metabolic process GO:0046033 8 0.022
regulation of secretion GO:0051046 224 0.022
telencephalon development GO:0021537 62 0.022
cellular lipid catabolic process GO:0044242 37 0.022
response to calcium ion GO:0051592 59 0.021
positive regulation of catalytic activity GO:0043085 184 0.021
small gtpase mediated signal transduction GO:0007264 36 0.021
lipid biosynthetic process GO:0008610 128 0.021
positive regulation of transport GO:0051050 245 0.021
regulation of cell projection organization GO:0031344 175 0.021
response to wounding GO:0009611 254 0.021
purine nucleoside triphosphate metabolic process GO:0009144 141 0.021
cellular response to peptide GO:1901653 133 0.021
ribonucleotide biosynthetic process GO:0009260 85 0.021
cellular response to cytokine stimulus GO:0071345 127 0.021
regulation of anatomical structure morphogenesis GO:0022603 141 0.020
glycosyl compound metabolic process GO:1901657 182 0.020
cellular component movement GO:0006928 248 0.020
purine nucleotide biosynthetic process GO:0006164 83 0.020
organelle organization GO:0006996 266 0.020
learning or memory GO:0007611 90 0.020
locomotion GO:0040011 237 0.020
cellular chemical homeostasis GO:0055082 247 0.020
purine ribonucleoside metabolic process GO:0046128 168 0.020
organic hydroxy compound metabolic process GO:1901615 115 0.020
head development GO:0060322 247 0.020
single organism cellular localization GO:1902580 102 0.020
liver development GO:0001889 90 0.020
response to biotic stimulus GO:0009607 226 0.019
monosaccharide metabolic process GO:0005996 61 0.019
cellular metal ion homeostasis GO:0006875 172 0.019
response to carbohydrate GO:0009743 183 0.019
antral ovarian follicle growth GO:0001547 3 0.019
sterol homeostasis GO:0055092 3 0.019
positive regulation of cell differentiation GO:0045597 217 0.019
cholesterol homeostasis GO:0042632 3 0.019
hexose metabolic process GO:0019318 58 0.019
protein oligomerization GO:0051259 191 0.019
cellular amino acid biosynthetic process GO:0008652 32 0.019
single organism reproductive process GO:0044702 297 0.019
positive regulation of cellular component organization GO:0051130 200 0.019
negative regulation of cell differentiation GO:0045596 99 0.018
multi organism reproductive process GO:0044703 262 0.018
cellular homeostasis GO:0019725 252 0.018
regulation of secretion by cell GO:1903530 208 0.018
response to estradiol GO:0032355 164 0.018
positive regulation of intracellular signal transduction GO:1902533 138 0.018
regulation of transcription dna templated GO:0006355 374 0.018
neuron projection development GO:0031175 273 0.018
regulation of cell proliferation GO:0042127 359 0.018
reproductive system development GO:0061458 128 0.018
transcription dna templated GO:0006351 377 0.018
developmental growth GO:0048589 100 0.018
vesicle mediated transport GO:0016192 181 0.018
steroid metabolic process GO:0008202 73 0.017
programmed cell death GO:0012501 392 0.017
purine containing compound biosynthetic process GO:0072522 85 0.017
regulation of protein phosphorylation GO:0001932 183 0.017
amine metabolic process GO:0009308 38 0.017
aromatic compound catabolic process GO:0019439 168 0.017
organonitrogen compound catabolic process GO:1901565 179 0.017
regulation of rna biosynthetic process GO:2001141 381 0.017
regulation of purine nucleotide metabolic process GO:1900542 115 0.017
ion homeostasis GO:0050801 212 0.017
response to estrogen GO:0043627 232 0.017
purine ribonucleotide biosynthetic process GO:0009152 81 0.016
positive regulation of nervous system development GO:0051962 178 0.016
nucleoside triphosphate metabolic process GO:0009141 144 0.016
regulation of programmed cell death GO:0043067 341 0.016
circulatory system development GO:0072359 134 0.016
regulation of cellular amino acid metabolic process GO:0006521 2 0.016
purine containing compound catabolic process GO:0072523 138 0.016
regulation of intracellular signal transduction GO:1902531 218 0.016
blood circulation GO:0008015 183 0.016
protein phosphorylation GO:0006468 345 0.016
positive regulation of signaling GO:0023056 270 0.016
growth GO:0040007 165 0.016
carbohydrate derivative catabolic process GO:1901136 147 0.016
alpha amino acid metabolic process GO:1901605 71 0.016
regulation of nucleotide metabolic process GO:0006140 117 0.016
cell part morphogenesis GO:0032990 123 0.016
regulation of lipid metabolic process GO:0019216 68 0.016
intracellular transport GO:0046907 185 0.016
synaptic growth at neuromuscular junction GO:0051124 1 0.016
embryonic pattern specification GO:0009880 1 0.016
negative regulation of cellular biosynthetic process GO:0031327 161 0.015
positive regulation of response to stimulus GO:0048584 285 0.015
negative regulation of biosynthetic process GO:0009890 168 0.015
heterocycle catabolic process GO:0046700 167 0.015
cellular component morphogenesis GO:0032989 155 0.015
positive regulation of cell development GO:0010720 176 0.015
gonad development GO:0008406 104 0.015
ribonucleoside triphosphate metabolic process GO:0009199 141 0.015
triglyceride metabolic process GO:0006641 21 0.015
positive regulation of rna biosynthetic process GO:1902680 197 0.015
wnt signaling pathway planar cell polarity pathway GO:0060071 2 0.015
amino acid transport GO:0006865 70 0.015
single organism intracellular transport GO:1902582 166 0.015
positive regulation of purine nucleotide metabolic process GO:1900544 91 0.015
immune system process GO:0002376 204 0.015
forebrain development GO:0030900 98 0.015
single organism organelle organization GO:1902589 180 0.015
cell communication involved in cardiac conduction GO:0086065 2 0.015
response to cytokine GO:0034097 215 0.015
cation homeostasis GO:0055080 195 0.015
response to purine containing compound GO:0014074 126 0.015
regulation of neurotransmitter levels GO:0001505 42 0.015
sex differentiation GO:0007548 113 0.015
positive regulation of cellular amine metabolic process GO:0033240 3 0.015
neuron development GO:0048666 286 0.015
hormone metabolic process GO:0042445 69 0.015
cardiac conduction GO:0061337 2 0.015
ribonucleotide catabolic process GO:0009261 136 0.015
nucleoside catabolic process GO:0009164 126 0.015
developmental process involved in reproduction GO:0003006 159 0.015
positive regulation of cell communication GO:0010647 271 0.015
regulation of catalytic activity GO:0050790 304 0.014
deoxyribose phosphate metabolic process GO:0019692 9 0.014
axis specification GO:0009798 4 0.014
response to decreased oxygen levels GO:0036293 237 0.014
Rat
cation transmembrane transport GO:0098655 263 0.014
peptidyl amino acid modification GO:0018193 126 0.014
organophosphate catabolic process GO:0046434 148 0.014
negative regulation of nervous system development GO:0051961 79 0.014
fatty acid transport GO:0015908 25 0.014
regulation of protein metabolic process GO:0051246 289 0.014
dephosphorylation GO:0016311 98 0.014
regulation of protein modification process GO:0031399 194 0.014
positive regulation of cell death GO:0010942 184 0.014
organic acid biosynthetic process GO:0016053 83 0.014
cell morphogenesis involved in differentiation GO:0000904 119 0.014
cytoplasmic transport GO:0016482 115 0.014
circulatory system process GO:0003013 183 0.014
divalent inorganic cation homeostasis GO:0072507 165 0.014
defense response GO:0006952 194 0.014
hormone secretion GO:0046879 115 0.014
response to molecule of bacterial origin GO:0002237 194 0.014
response to alkaloid GO:0043279 132 0.013
metal ion homeostasis GO:0055065 186 0.013
cellular nitrogen compound catabolic process GO:0044270 163 0.013
negative regulation of transport GO:0051051 136 0.013
regulation of locomotion GO:0040012 148 0.013
positive regulation of phosphorylation GO:0042327 177 0.013
reproductive structure development GO:0048608 128 0.013
lipid transport GO:0006869 61 0.013
positive regulation of protein modification process GO:0031401 142 0.013
regulation of catabolic process GO:0009894 113 0.013
response to fatty acid GO:0070542 65 0.013
positive regulation of neurogenesis GO:0050769 165 0.013
monovalent inorganic cation transport GO:0015672 172 0.013
monocarboxylic acid biosynthetic process GO:0072330 48 0.013
metal ion transport GO:0030001 289 0.013
positive regulation of cellular catabolic process GO:0031331 71 0.013
circadian rhythm GO:0007623 88 0.013
peptide secretion GO:0002790 86 0.013
cofactor metabolic process GO:0051186 95 0.013
anterior posterior pattern specification GO:0009952 1 0.013
sensory perception GO:0007600 101 0.013
regulation of peptide transport GO:0090087 87 0.013
hormone transport GO:0009914 121 0.013
negative regulation of cellular metabolic process GO:0031324 281 0.013
purine nucleoside metabolic process GO:0042278 169 0.013
regulation of homeostatic process GO:0032844 101 0.013
regulation of cellular amine metabolic process GO:0033238 8 0.013
female gonad development GO:0008585 53 0.013
cellular response to organic cyclic compound GO:0071407 202 0.013
cyclic nucleotide metabolic process GO:0009187 80 0.013
response to ketone GO:1901654 182 0.013
protein localization GO:0008104 191 0.012
nucleic acid templated transcription GO:0097659 379 0.012
purine ribonucleoside catabolic process GO:0046130 124 0.012
aging GO:0007568 241 0.012
Rat
positive regulation of cellular protein metabolic process GO:0032270 167 0.012
response to insulin GO:0032868 133 0.012
nucleoside phosphate catabolic process GO:1901292 140 0.012
eye morphogenesis GO:0048592 4 0.012
regulation of phosphorylation GO:0042325 248 0.012
regulation of hormone secretion GO:0046883 106 0.012
regulation of apoptotic process GO:0042981 335 0.012
purine nucleoside diphosphate metabolic process GO:0009135 9 0.012
anatomical structure formation involved in morphogenesis GO:0048646 83 0.012
Fly
regulation of response to external stimulus GO:0032101 106 0.012
response to glucose GO:0009749 136 0.012
carboxylic acid biosynthetic process GO:0046394 83 0.012
peptide transport GO:0015833 97 0.012
regulation of canonical wnt signaling pathway GO:0060828 4 0.012
cellular response to acid chemical GO:0071229 75 0.012
response to hexose GO:0009746 144 0.012
negative regulation of phosphate metabolic process GO:0045936 80 0.012
regulation of nucleic acid templated transcription GO:1903506 380 0.012
regulation of membrane potential GO:0042391 110 0.012
amino acid betaine metabolic process GO:0006577 3 0.011
gtp catabolic process GO:0006184 71 0.011
regulation of blood circulation GO:1903522 110 0.011
ribonucleoside catabolic process GO:0042454 126 0.011
nucleobase containing compound catabolic process GO:0034655 152 0.011
cellular divalent inorganic cation homeostasis GO:0072503 162 0.011
glucose metabolic process GO:0006006 52 0.011
positive regulation of neuron differentiation GO:0045666 126 0.011
negative regulation of cellular component organization GO:0051129 83 0.011
negative regulation of metabolic process GO:0009892 331 0.011
glycosyl compound catabolic process GO:1901658 126 0.011
endoplasmic reticulum organization GO:0007029 1 0.011
sensory organ development GO:0007423 74 0.011
cellular response to growth factor stimulus GO:0071363 162 0.011
embryo development GO:0009790 49 0.011
Fly
acylglycerol metabolic process GO:0006639 21 0.011
regulation of cell migration GO:0030334 128 0.011
regulation of fatty acid beta oxidation GO:0031998 8 0.011
negative regulation of cell development GO:0010721 82 0.011
establishment of tissue polarity GO:0007164 2 0.011
gamete generation GO:0007276 124 0.011
cellular amide metabolic process GO:0043603 44 0.011
positive regulation of catabolic process GO:0009896 78 0.011
regulation of synaptic transmission GO:0050804 141 0.011
regulation of peptide secretion GO:0002791 82 0.011
response to growth factor GO:0070848 189 0.011
cell morphogenesis GO:0000902 142 0.011
rho protein signal transduction GO:0007266 11 0.011
response to oxidative stress GO:0006979 186 0.011
heart morphogenesis GO:0003007 3 0.011
asymmetric protein localization GO:0008105 2 0.011
atp metabolic process GO:0046034 72 0.011
cytokine mediated signaling pathway GO:0019221 43 0.011
response to mechanical stimulus GO:0009612 134 0.011
glycerolipid metabolic process GO:0046486 67 0.011
neuron neuron synaptic transmission GO:0007270 60 0.011
nucleoside diphosphate metabolic process GO:0009132 14 0.011
regulation of peptide hormone secretion GO:0090276 80 0.011
purine nucleoside diphosphate biosynthetic process GO:0009136 9 0.011
male gamete generation GO:0048232 99 0.011
hexose catabolic process GO:0019320 10 0.011
response to retinoic acid GO:0032526 63 0.011
Rat
negative regulation of macromolecule metabolic process GO:0010605 260 0.011
negative regulation of response to stimulus GO:0048585 155 0.011
negative regulation of signal transduction GO:0009968 83 0.011
regulation of cellular component movement GO:0051270 150 0.010
glycosyl compound biosynthetic process GO:1901659 25 0.010
gastrulation GO:0007369 2 0.010
Fly
cellular ion homeostasis GO:0006873 184 0.010
non canonical wnt signaling pathway GO:0035567 3 0.010
calcium ion homeostasis GO:0055074 162 0.010
regulation of response to stress GO:0080134 126 0.010
regulation of system process GO:0044057 208 0.010
sexual reproduction GO:0019953 148 0.010
ovulation cycle process GO:0022602 50 0.010
lipid storage GO:0019915 1 0.010
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.010
purine nucleotide catabolic process GO:0006195 136 0.010
transmission of nerve impulse GO:0019226 42 0.010

Aco1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.051
inherited metabolic disorder DOID:655 0 0.048
disease of anatomical entity DOID:7 0 0.042
musculoskeletal system disease DOID:17 0 0.042
nervous system disease DOID:863 0 0.024
central nervous system disease DOID:331 0 0.016
myopathy DOID:423 0 0.013
muscular disease DOID:0080000 0 0.013
muscle tissue disease DOID:66 0 0.013
disease of cellular proliferation DOID:14566 0 0.013
heart disease DOID:114 0 0.013
cardiomyopathy DOID:0050700 0 0.013
intrinsic cardiomyopathy DOID:0060036 0 0.013
cardiovascular system disease DOID:1287 0 0.013
arrhythmogenic right ventricular cardiomyopathy DOID:0050431 0 0.013
carbohydrate metabolic disorder DOID:2978 0 0.013