Rattus norvegicus

0 known processes

Rics

Rho GTPase-activating protein

(Aliases: Grit)

Rics biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
regulation of transcription dna templated GO:0006355 374 0.083
regulation of rna metabolic process GO:0051252 391 0.082
transcription dna templated GO:0006351 377 0.078
rna metabolic process GO:0016070 406 0.077
rna biosynthetic process GO:0032774 380 0.069
protein phosphorylation GO:0006468 345 0.068
regulation of nucleic acid templated transcription GO:1903506 380 0.066
negative regulation of metabolic process GO:0009892 331 0.062
cell projection organization GO:0030030 302 0.060
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.060
protein complex biogenesis GO:0070271 263 0.057
cell morphogenesis GO:0000902 142 0.056
regulation of rna biosynthetic process GO:2001141 381 0.055
negative regulation of macromolecule metabolic process GO:0010605 260 0.055
regulation of cell differentiation GO:0045595 320 0.055
protein complex assembly GO:0006461 263 0.054
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.051
nucleic acid templated transcription GO:0097659 379 0.050
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.048
behavior GO:0007610 205 0.044
regulation of molecular function GO:0065009 398 0.041
cellular component morphogenesis GO:0032989 155 0.041
positive regulation of biosynthetic process GO:0009891 319 0.041
negative regulation of programmed cell death GO:0043069 183 0.040
cation transport GO:0006812 382 0.039
regulation of multicellular organismal development GO:2000026 376 0.039
neuron projection development GO:0031175 273 0.039
regulation of cellular component organization GO:0051128 368 0.039
regulation of apoptotic process GO:0042981 335 0.038
cell projection morphogenesis GO:0048858 123 0.038
cellular response to oxygen containing compound GO:1901701 386 0.037
positive regulation of gene expression GO:0010628 244 0.037
single organism intracellular transport GO:1902582 166 0.037
protein complex subunit organization GO:0071822 302 0.037
neuron projection morphogenesis GO:0048812 122 0.037
macromolecular complex subunit organization GO:0043933 339 0.036
negative regulation of nucleic acid templated transcription GO:1903507 117 0.035
oxoacid metabolic process GO:0043436 290 0.035
positive regulation of molecular function GO:0044093 230 0.034
neurological system process GO:0050877 219 0.034
macromolecular complex assembly GO:0065003 273 0.034
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.033
intracellular transport GO:0046907 185 0.033
positive regulation of transcription dna templated GO:0045893 197 0.033
positive regulation of cellular biosynthetic process GO:0031328 295 0.032
positive regulation of rna biosynthetic process GO:1902680 197 0.032
positive regulation of synapse maturation GO:0090129 2 0.032
cellular component biogenesis GO:0044085 368 0.032
regulation of phosphorus metabolic process GO:0051174 349 0.032
regulation of cellular amino acid metabolic process GO:0006521 2 0.032
cellular amino acid metabolic process GO:0006520 107 0.031
amine metabolic process GO:0009308 38 0.031
carboxylic acid metabolic process GO:0019752 289 0.031
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.031
neuron differentiation GO:0030182 368 0.031
negative regulation of gene expression GO:0010629 199 0.031
regulation of phosphate metabolic process GO:0019220 349 0.031
organelle organization GO:0006996 266 0.030
cellular component assembly GO:0022607 360 0.030
negative regulation of biosynthetic process GO:0009890 168 0.030
response to extracellular stimulus GO:0009991 380 0.030
regulation of neuron projection development GO:0010975 161 0.030
negative regulation of cellular metabolic process GO:0031324 281 0.030
response to oxygen levels GO:0070482 265 0.029
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.029
multi organism reproductive process GO:0044703 262 0.029
negative regulation of apoptotic process GO:0043066 181 0.029
cell morphogenesis involved in differentiation GO:0000904 119 0.029
organic acid metabolic process GO:0006082 292 0.029
response to carbohydrate GO:0009743 183 0.028
cell part morphogenesis GO:0032990 123 0.028
response to nutrient levels GO:0031667 370 0.027
regulation of cellular amine metabolic process GO:0033238 8 0.027
regulation of phosphorylation GO:0042325 248 0.027
reproductive process GO:0022414 372 0.026
positive regulation of developmental process GO:0051094 283 0.026
regulation of cellular ketone metabolic process GO:0010565 27 0.026
cellular ketone metabolic process GO:0042180 51 0.026
regulation of cell morphogenesis involved in differentiation GO:0010769 72 0.025
negative regulation of transcription dna templated GO:0045892 116 0.025
regulation of neuron differentiation GO:0045664 208 0.025
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.025
positive regulation of cell differentiation GO:0045597 217 0.025
cellular amine metabolic process GO:0044106 38 0.025
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.025
positive regulation of signaling GO:0023056 270 0.024
transcription from rna polymerase ii promoter GO:0006366 252 0.024
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.024
synaptic growth at neuromuscular junction GO:0051124 1 0.024
regulation of catalytic activity GO:0050790 304 0.024
peptidyl amino acid modification GO:0018193 126 0.024
dna metabolic process GO:0006259 96 0.023
negative regulation of rna metabolic process GO:0051253 123 0.023
negative regulation of rna biosynthetic process GO:1902679 118 0.023
regulation of anatomical structure morphogenesis GO:0022603 141 0.023
programmed cell death GO:0012501 392 0.023
catabolic process GO:0009056 351 0.023
single organism organelle organization GO:1902589 180 0.022
positive regulation of rna metabolic process GO:0051254 203 0.022
regulation of synapse maturation GO:0090128 2 0.022
regulation of nervous system development GO:0051960 264 0.022
multicellular organismal reproductive process GO:0048609 233 0.022
positive regulation of cellular component organization GO:0051130 200 0.022
response to nutrient GO:0007584 248 0.022
regulation of system process GO:0044057 208 0.021
homeostatic process GO:0042592 331 0.021
cellular response to nitrogen compound GO:1901699 210 0.021
synaptic transmission GO:0007268 235 0.021
cell cell signaling GO:0007267 335 0.021
organophosphate metabolic process GO:0019637 370 0.021
regulation of cell development GO:0060284 263 0.021
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.020
positive regulation of multicellular organismal process GO:0051240 387 0.020
locomotion GO:0040011 237 0.020
carbohydrate derivative metabolic process GO:1901135 346 0.020
anatomical structure morphogenesis GO:0009653 298 0.020
cell morphogenesis involved in neuron differentiation GO:0048667 106 0.020
positive regulation of cell communication GO:0010647 271 0.020
cellular response to endogenous stimulus GO:0071495 377 0.020
dendrite development GO:0016358 72 0.019
regulation of protein metabolic process GO:0051246 289 0.019
metal ion transport GO:0030001 289 0.019
multicellular organism reproduction GO:0032504 233 0.019
negative regulation of cell death GO:0060548 229 0.019
nucleobase containing small molecule metabolic process GO:0055086 316 0.019
regulation of homeostatic process GO:0032844 101 0.019
single organism carbohydrate metabolic process GO:0044723 118 0.019
response to hypoxia GO:0001666 231 0.019
apoptotic process GO:0006915 381 0.019
regulation of protein phosphorylation GO:0001932 183 0.018
regulation of signal transduction GO:0009966 318 0.018
cellular response to hormone stimulus GO:0032870 247 0.018
response to cytokine GO:0034097 215 0.018
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.018
positive regulation of nucleic acid templated transcription GO:1903508 197 0.018
cellular catabolic process GO:0044248 295 0.018
aging GO:0007568 241 0.017
ribose phosphate metabolic process GO:0019693 235 0.017
ion transmembrane transport GO:0034220 365 0.017
axonogenesis GO:0007409 71 0.017
negative regulation of cellular biosynthetic process GO:0031327 161 0.017
regulation of hormone levels GO:0010817 187 0.017
dendrite morphogenesis GO:0048813 43 0.017
positive regulation of phosphorus metabolic process GO:0010562 262 0.017
ribonucleoside metabolic process GO:0009119 174 0.017
regulation of cell projection organization GO:0031344 175 0.017
reproduction GO:0000003 245 0.017
single organism behavior GO:0044708 130 0.017
single organism catabolic process GO:0044712 283 0.016
regulation of axonogenesis GO:0050770 37 0.016
response to acid chemical GO:0001101 222 0.016
single organism biosynthetic process GO:0044711 342 0.016
organic substance catabolic process GO:1901575 316 0.016
regulation of growth GO:0040008 105 0.016
response to glucose GO:0009749 136 0.016
regulation of programmed cell death GO:0043067 341 0.016
positive regulation of nervous system development GO:0051962 178 0.016
developmental process involved in reproduction GO:0003006 159 0.016
single organism reproductive process GO:0044702 297 0.016
positive regulation of cellular amine metabolic process GO:0033240 3 0.016
positive regulation of cell development GO:0010720 176 0.016
purine ribonucleotide metabolic process GO:0009150 227 0.016
nucleoside phosphate metabolic process GO:0006753 283 0.015
monocarboxylic acid metabolic process GO:0032787 152 0.015
regulation of anatomical structure size GO:0090066 135 0.015
cellular macromolecular complex assembly GO:0034622 58 0.015
protein autophosphorylation GO:0046777 66 0.015
response to estrogen GO:0043627 232 0.015
response to hexose GO:0009746 144 0.015
response to monosaccharide GO:0034284 159 0.015
regulation of protein kinase activity GO:0045859 105 0.015
regulation of cellular protein metabolic process GO:0032268 267 0.015
axon development GO:0061564 96 0.015
response to ethanol GO:0045471 162 0.015
anterior posterior pattern specification GO:0009952 1 0.014
positive regulation of catalytic activity GO:0043085 184 0.014
protein oligomerization GO:0051259 191 0.014
cellular response to insulin stimulus GO:0032869 81 0.014
hormone secretion GO:0046879 115 0.014
negative regulation of multicellular organismal process GO:0051241 203 0.014
regulation of protein modification process GO:0031399 194 0.014
tissue development GO:0009888 252 0.014
cell cycle GO:0007049 101 0.014
negative regulation of molecular function GO:0044092 133 0.014
response to peptide GO:1901652 292 0.014
regulation of dendrite development GO:0050773 59 0.014
regulation of proteasomal protein catabolic process GO:0061136 4 0.014
anion transport GO:0006820 178 0.014
gastrulation GO:0007369 2 0.014
oxidation reduction process GO:0055114 304 0.014
growth GO:0040007 165 0.014
regulation of cell cycle GO:0051726 73 0.014
negative regulation of response to stimulus GO:0048585 155 0.013
cellular homeostasis GO:0019725 252 0.013
organic cyclic compound catabolic process GO:1901361 175 0.013
intracellular signal transduction GO:0035556 314 0.013
amide transport GO:0042886 105 0.013
cytoplasmic transport GO:0016482 115 0.013
negative regulation of phosphate metabolic process GO:0045936 80 0.013
axis specification GO:0009798 4 0.013
monosaccharide metabolic process GO:0005996 61 0.013
regulation of cell proliferation GO:0042127 359 0.013
peptidyl tyrosine phosphorylation GO:0018108 72 0.013
regulation of membrane potential GO:0042391 110 0.013
chemical homeostasis GO:0048878 292 0.013
regulation of cellular localization GO:0060341 263 0.013
transmembrane transport GO:0055085 412 0.013
cellular chemical homeostasis GO:0055082 247 0.012
response to decreased oxygen levels GO:0036293 237 0.012
regulation of dendrite morphogenesis GO:0048814 33 0.012
negative regulation of phosphorus metabolic process GO:0010563 80 0.012
gamete generation GO:0007276 124 0.012
lipid metabolic process GO:0006629 283 0.012
response to insulin GO:0032868 133 0.012
gland development GO:0048732 155 0.012
response to other organism GO:0051707 220 0.012
nucleotide metabolic process GO:0009117 279 0.012
positive regulation of cell proliferation GO:0008284 249 0.012
regulation of transferase activity GO:0051338 123 0.012
heart morphogenesis GO:0003007 3 0.012
carbohydrate derivative biosynthetic process GO:1901137 124 0.012
regulation of canonical wnt signaling pathway GO:0060828 4 0.012
secretion GO:0046903 307 0.012
positive regulation of phosphate metabolic process GO:0045937 262 0.012
cellular response to organonitrogen compound GO:0071417 197 0.012
positive regulation of cell morphogenesis involved in differentiation GO:0010770 41 0.012
spindle organization GO:0007051 2 0.012
vesicle mediated transport GO:0016192 181 0.012
regulation of dna metabolic process GO:0051052 60 0.012
negative regulation of cellular protein metabolic process GO:0032269 106 0.011
negative regulation of protein metabolic process GO:0051248 114 0.011
positive regulation of protein modification process GO:0031401 142 0.011
salivary gland development GO:0007431 3 0.011
embryonic pattern specification GO:0009880 1 0.011
ion homeostasis GO:0050801 212 0.011
response to biotic stimulus GO:0009607 226 0.011
regulation of cellular component size GO:0032535 51 0.011
response to purine containing compound GO:0014074 126 0.011
cellular response to stress GO:0033554 269 0.011
small gtpase mediated signal transduction GO:0007264 36 0.011
regulation of ion transport GO:0043269 245 0.011
negative regulation of cellular component organization GO:0051129 83 0.011
cell growth GO:0016049 104 0.011
macromolecule localization GO:0033036 252 0.011
positive regulation of cell projection organization GO:0031346 111 0.011
response to external biotic stimulus GO:0043207 221 0.011
response to bacterium GO:0009617 200 0.011
ras protein signal transduction GO:0007265 29 0.011
negative regulation of catalytic activity GO:0043086 103 0.011
salivary gland morphogenesis GO:0007435 1 0.011
negative regulation of phosphorylation GO:0042326 57 0.011
positive regulation of protein metabolic process GO:0051247 178 0.011
urogenital system development GO:0001655 78 0.011
cellular response to cytokine stimulus GO:0071345 127 0.010
cytoskeleton dependent cytokinesis GO:0061640 2 0.010
g protein coupled receptor signaling pathway GO:0007186 242 0.010
regulation of neurogenesis GO:0050767 247 0.010
lipid storage GO:0019915 1 0.010
actin filament based process GO:0030029 86 0.010
sexual reproduction GO:0019953 148 0.010
neuronal action potential GO:0019228 35 0.010
intracellular receptor signaling pathway GO:0030522 35 0.010
head development GO:0060322 247 0.010
response to peptide hormone GO:0043434 278 0.010
negative regulation of neurogenesis GO:0050768 78 0.010
regulation of g0 to g1 transition GO:0070316 3 0.010
positive regulation of secretion by cell GO:1903532 128 0.010
cation homeostasis GO:0055080 195 0.010
purine containing compound metabolic process GO:0072521 253 0.010
nitrogen compound transport GO:0071705 229 0.010

Rics disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of cellular proliferation DOID:14566 0 0.018
cancer DOID:162 0 0.017
nervous system disease DOID:863 0 0.013
disease of anatomical entity DOID:7 0 0.013
organ system cancer DOID:0050686 0 0.013