Rattus norvegicus

0 known processes

Spink5

serine peptidase inhibitor, Kazal type 5

Spink5 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
tissue development GO:0009888 252 0.236
single organism reproductive process GO:0044702 297 0.158
reproductive process GO:0022414 372 0.133
negative regulation of gene expression GO:0010629 199 0.130
response to growth factor GO:0070848 189 0.116
multicellular organism reproduction GO:0032504 233 0.109
positive regulation of biosynthetic process GO:0009891 319 0.106
transcription dna templated GO:0006351 377 0.096
positive regulation of cell proliferation GO:0008284 249 0.093
action potential GO:0001508 54 0.093
multi multicellular organism process GO:0044706 138 0.083
response to other organism GO:0051707 220 0.080
oxoacid metabolic process GO:0043436 290 0.077
response to external biotic stimulus GO:0043207 221 0.076
proteolysis GO:0006508 175 0.068
response to metal ion GO:0010038 253 0.066
single organism biosynthetic process GO:0044711 342 0.066
regulation of cell proliferation GO:0042127 359 0.065
response to toxic substance GO:0009636 133 0.065
positive regulation of gene expression GO:0010628 244 0.063
positive regulation of cellular biosynthetic process GO:0031328 295 0.060
epithelial cell differentiation GO:0030855 71 0.058
negative regulation of metabolic process GO:0009892 331 0.057
positive regulation of molecular function GO:0044093 230 0.056
response to radiation GO:0009314 137 0.055
negative regulation of rna metabolic process GO:0051253 123 0.053
behavior GO:0007610 205 0.052
regulation of hormone levels GO:0010817 187 0.050
regulation of cell development GO:0060284 263 0.049
positive regulation of cell communication GO:0010647 271 0.048
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.047
organic hydroxy compound metabolic process GO:1901615 115 0.047
immune response GO:0006955 104 0.047
multicellular organismal reproductive process GO:0048609 233 0.046
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.046
regulation of epithelial cell proliferation GO:0050678 49 0.045
aging GO:0007568 241 0.043
positive regulation of nucleic acid templated transcription GO:1903508 197 0.043
carboxylic acid metabolic process GO:0019752 289 0.042
rna metabolic process GO:0016070 406 0.041
regulation of multicellular organismal development GO:2000026 376 0.039
neuron differentiation GO:0030182 368 0.039
reproduction GO:0000003 245 0.038
anatomical structure morphogenesis GO:0009653 298 0.037
negative regulation of cell death GO:0060548 229 0.037
cell cell signaling GO:0007267 335 0.037
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.037
hormone metabolic process GO:0042445 69 0.037
negative regulation of transcription dna templated GO:0045892 116 0.036
response to molecule of bacterial origin GO:0002237 194 0.036
gonad development GO:0008406 104 0.036
wound healing GO:0042060 122 0.036
amine metabolic process GO:0009308 38 0.036
negative regulation of multicellular organismal process GO:0051241 203 0.035
response to transition metal nanoparticle GO:1990267 122 0.035
negative regulation of cellular metabolic process GO:0031324 281 0.035
cellular amino acid metabolic process GO:0006520 107 0.035
biological adhesion GO:0022610 110 0.035
multi organism reproductive process GO:0044703 262 0.034
epithelial cell proliferation GO:0050673 54 0.034
immune system process GO:0002376 204 0.033
cellular protein localization GO:0034613 122 0.033
cardiovascular system development GO:0072358 134 0.033
regulation of nucleic acid templated transcription GO:1903506 380 0.033
epithelium development GO:0060429 96 0.033
regulation of molecular function GO:0065009 398 0.032
embryonic cranial skeleton morphogenesis GO:0048701 2 0.032
negative regulation of rna biosynthetic process GO:1902679 118 0.032
response to ketone GO:1901654 182 0.032
transcription from rna polymerase ii promoter GO:0006366 252 0.031
regulation of protein phosphorylation GO:0001932 183 0.031
negative regulation of programmed cell death GO:0043069 183 0.030
response to insulin GO:0032868 133 0.030
sex differentiation GO:0007548 113 0.030
positive regulation of response to stimulus GO:0048584 285 0.030
tongue morphogenesis GO:0043587 3 0.029
cytosolic calcium ion homeostasis GO:0051480 140 0.029
cellular response to lipid GO:0071396 201 0.028
male sex differentiation GO:0046661 64 0.028
positive regulation of transcription dna templated GO:0045893 197 0.028
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.028
positive regulation of phosphate metabolic process GO:0045937 262 0.027
single organism behavior GO:0044708 130 0.026
circulatory system development GO:0072359 134 0.026
central nervous system development GO:0007417 311 0.026
rhythmic process GO:0048511 156 0.026
regulation of cellular amine metabolic process GO:0033238 8 0.026
programmed cell death GO:0012501 392 0.025
regulation of transcription dna templated GO:0006355 374 0.025
response to nutrient levels GO:0031667 370 0.025
regulation of cellular protein metabolic process GO:0032268 267 0.025
cellular ketone metabolic process GO:0042180 51 0.025
response to oxidative stress GO:0006979 186 0.025
response to cytokine GO:0034097 215 0.024
response to extracellular stimulus GO:0009991 380 0.024
regulation of signal transduction GO:0009966 318 0.024
mapk cascade GO:0000165 140 0.024
regulation of programmed cell death GO:0043067 341 0.024
neurological system process GO:0050877 219 0.024
intracellular transport GO:0046907 185 0.024
embryonic skeletal system development GO:0048706 3 0.023
positive regulation of developmental process GO:0051094 283 0.023
regulation of protein modification process GO:0031399 194 0.023
macromolecule localization GO:0033036 252 0.023
positive regulation of intracellular signal transduction GO:1902533 138 0.023
peptidyl tyrosine modification GO:0018212 72 0.023
cellular component biogenesis GO:0044085 368 0.022
regulation of cell differentiation GO:0045595 320 0.022
response to ionizing radiation GO:0010212 59 0.022
cell adhesion GO:0007155 110 0.022
organelle organization GO:0006996 266 0.022
sexual reproduction GO:0019953 148 0.021
positive regulation of phosphorus metabolic process GO:0010562 262 0.021
rna biosynthetic process GO:0032774 380 0.021
positive regulation of protein metabolic process GO:0051247 178 0.021
regeneration GO:0031099 163 0.021
cellular response to growth factor stimulus GO:0071363 162 0.021
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.021
ovulation cycle GO:0042698 67 0.021
intracellular signal transduction GO:0035556 314 0.021
multicellular organismal homeostasis GO:0048871 49 0.020
positive regulation of signal transduction GO:0009967 175 0.020
signal transduction by phosphorylation GO:0023014 144 0.020
forebrain development GO:0030900 98 0.020
cellular amine metabolic process GO:0044106 38 0.020
positive regulation of rna metabolic process GO:0051254 203 0.019
male gonad development GO:0008584 59 0.019
regulation of system process GO:0044057 208 0.019
protein complex biogenesis GO:0070271 263 0.019
negative regulation of cellular biosynthetic process GO:0031327 161 0.019
actin filament based process GO:0030029 86 0.019
negative regulation of neuron differentiation GO:0045665 62 0.019
cognition GO:0050890 92 0.018
regulation of catalytic activity GO:0050790 304 0.018
negative regulation of developmental process GO:0051093 125 0.018
peptidyl tyrosine phosphorylation GO:0018108 72 0.018
cellular hormone metabolic process GO:0034754 49 0.018
gamete generation GO:0007276 124 0.018
organic acid metabolic process GO:0006082 292 0.018
negative regulation of macromolecule metabolic process GO:0010605 260 0.017
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.017
positive regulation of phosphorylation GO:0042327 177 0.017
reproductive system development GO:0061458 128 0.017
localization of cell GO:0051674 202 0.017
response to ethanol GO:0045471 162 0.017
regulation of phosphorylation GO:0042325 248 0.017
leukocyte cell cell adhesion GO:0007159 4 0.017
cellular chemical homeostasis GO:0055082 247 0.016
regulation of transferase activity GO:0051338 123 0.016
response to peptide GO:1901652 292 0.016
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.016
micturition GO:0060073 4 0.016
protein phosphorylation GO:0006468 345 0.016
organophosphate metabolic process GO:0019637 370 0.016
positive regulation of kinase activity GO:0033674 77 0.016
circulatory system process GO:0003013 183 0.016
negative regulation of biosynthetic process GO:0009890 168 0.016
anterior posterior pattern specification GO:0009952 1 0.016
regulation of mapk cascade GO:0043408 116 0.016
monocarboxylic acid metabolic process GO:0032787 152 0.016
regulation of protein maturation GO:1903317 50 0.015
regulation of cyclic nucleotide metabolic process GO:0030799 51 0.015
response to acid chemical GO:0001101 222 0.015
regulation of rna metabolic process GO:0051252 391 0.015
transmission of nerve impulse GO:0019226 42 0.015
negative regulation of protein maturation GO:1903318 47 0.015
neuronal action potential GO:0019228 35 0.015
reproductive structure development GO:0048608 128 0.015
negative regulation of nucleic acid templated transcription GO:1903507 117 0.015
cellular cation homeostasis GO:0030003 180 0.015
carboxylic acid biosynthetic process GO:0046394 83 0.015
response to lipopolysaccharide GO:0032496 191 0.015
negative regulation of molecular function GO:0044092 133 0.015
axis specification GO:0009798 4 0.015
single organism cell adhesion GO:0098602 46 0.014
cellular response to stress GO:0033554 269 0.014
regulation of vesicle mediated transport GO:0060627 81 0.014
regulation of phosphate metabolic process GO:0019220 349 0.014
cell motility GO:0048870 202 0.014
carbohydrate derivative metabolic process GO:1901135 346 0.014
response to biotic stimulus GO:0009607 226 0.014
positive regulation of cell differentiation GO:0045597 217 0.014
developmental growth GO:0048589 100 0.014
heart development GO:0007507 72 0.014
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.014
heart morphogenesis GO:0003007 3 0.014
cation transport GO:0006812 382 0.014
regulation of protein metabolic process GO:0051246 289 0.014
chemical homeostasis GO:0048878 292 0.014
protein maturation GO:0051604 68 0.014
protein oligomerization GO:0051259 191 0.013
regulation of cellular amino acid metabolic process GO:0006521 2 0.013
lipid metabolic process GO:0006629 283 0.013
positive regulation of cell development GO:0010720 176 0.013
cytoplasmic transport GO:0016482 115 0.013
response to vitamin GO:0033273 131 0.013
cellular component movement GO:0006928 248 0.013
negative regulation of proteolysis GO:0045861 41 0.013
response to inorganic substance GO:0010035 377 0.013
s shaped body morphogenesis GO:0072050 2 0.013
learning or memory GO:0007611 90 0.013
regulation of membrane potential GO:0042391 110 0.013
negative regulation of apoptotic process GO:0043066 181 0.013
negative regulation of cell proliferation GO:0008285 119 0.013
myeloid leukocyte differentiation GO:0002573 20 0.012
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.012
brain development GO:0007420 247 0.012
feeding behavior GO:0007631 53 0.012
hormone biosynthetic process GO:0042446 25 0.012
cellular catabolic process GO:0044248 295 0.012
cellular macromolecule localization GO:0070727 122 0.012
neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 3 0.012
neuron development GO:0048666 286 0.012
response to peptide hormone GO:0043434 278 0.012
interferon gamma production GO:0032609 3 0.012
lipid biosynthetic process GO:0008610 128 0.012
regulation of secretion GO:0051046 224 0.012
development of primary sexual characteristics GO:0045137 107 0.012
cellular response to endogenous stimulus GO:0071495 377 0.012
cellular homeostasis GO:0019725 252 0.012
alcohol biosynthetic process GO:0046165 38 0.012
mast cell chemotaxis GO:0002551 4 0.012
alcohol metabolic process GO:0006066 77 0.012
positive regulation of multicellular organismal process GO:0051240 387 0.012
positive regulation of protein phosphorylation GO:0001934 135 0.012
regulation of smooth muscle cell proliferation GO:0048660 75 0.011
regulation of protein processing GO:0070613 50 0.011
development of primary male sexual characteristics GO:0046546 59 0.011
regulation of proteolysis GO:0030162 66 0.011
cellular response to acid chemical GO:0071229 75 0.011
male gamete generation GO:0048232 99 0.011
positive regulation of cytosolic calcium ion concentration GO:0007204 122 0.011
lymphocyte migration GO:0072676 3 0.011
regulation of kinase activity GO:0043549 117 0.011
divalent inorganic cation homeostasis GO:0072507 165 0.011
protein localization to organelle GO:0033365 57 0.011
cellular component morphogenesis GO:0032989 155 0.011
regulation of neurogenesis GO:0050767 247 0.011
head development GO:0060322 247 0.011
muscle tissue development GO:0060537 58 0.011
cellular response to oxygen containing compound GO:1901701 386 0.011
apoptotic process GO:0006915 381 0.011
negative regulation of response to stimulus GO:0048585 155 0.011
cellular component assembly GO:0022607 360 0.011
response to wounding GO:0009611 254 0.010
regulation of phosphorus metabolic process GO:0051174 349 0.010
cell projection organization GO:0030030 302 0.010
cardiac chamber development GO:0003205 1 0.010
peptidyl amino acid modification GO:0018193 126 0.010
regulation of cellular component organization GO:0051128 368 0.010

Spink5 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.014
nervous system disease DOID:863 0 0.014