Rattus norvegicus

0 known processes

Spink1

serine peptidase inhibitor, Kazal type 1

(Aliases: Psti,Spink3)

Spink1 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
negative regulation of serine type peptidase activity GO:1902572 1 0.968
Mouse
regulation of serine type peptidase activity GO:1902571 1 0.818
Mouse
regulation of serine type endopeptidase activity GO:1900003 1 0.598
Mouse
response to nutrient GO:0007584 248 0.597
regulation of cellular protein metabolic process GO:0032268 267 0.584
Mouse Rat
carboxylic acid metabolic process GO:0019752 289 0.558
response to glucocorticoid GO:0051384 223 0.515
oxoacid metabolic process GO:0043436 290 0.507
lipid metabolic process GO:0006629 283 0.501
response to nutrient levels GO:0031667 370 0.477
response to corticosteroid GO:0031960 235 0.447
response to extracellular stimulus GO:0009991 380 0.385
extracellular matrix constituent secretion GO:0070278 4 0.367
inflammatory response GO:0006954 150 0.289
organic acid metabolic process GO:0006082 292 0.289
negative regulation of serine type endopeptidase activity GO:1900004 1 0.287
Mouse
regulation of catalytic activity GO:0050790 304 0.285
Mouse Rat
apoptotic process GO:0006915 381 0.266
cellular amino acid metabolic process GO:0006520 107 0.249
response to peptide GO:1901652 292 0.246
regulation of protein metabolic process GO:0051246 289 0.239
Mouse Rat
negative regulation of cell death GO:0060548 229 0.228
defense response GO:0006952 194 0.212
neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 3 0.191
circulatory system process GO:0003013 183 0.175
blood circulation GO:0008015 183 0.173
fatty acid metabolic process GO:0006631 99 0.170
positive regulation of cellular biosynthetic process GO:0031328 295 0.161
single organism biosynthetic process GO:0044711 342 0.161
positive regulation of extracellular matrix organization GO:1903055 4 0.153
positive regulation of transport GO:0051050 245 0.152
regulation of phosphate metabolic process GO:0019220 349 0.151
Mouse
cellular lipid metabolic process GO:0044255 208 0.144
response to carbohydrate GO:0009743 183 0.138
cellular response to lipid GO:0071396 201 0.137
calcitriol biosynthetic process from calciol GO:0036378 2 0.133
regulation of molecular function GO:0065009 398 0.129
Mouse Rat
response to estrogen GO:0043627 232 0.128
small molecule biosynthetic process GO:0044283 124 0.128
organophosphate metabolic process GO:0019637 370 0.127
response to inorganic substance GO:0010035 377 0.125
programmed cell death GO:0012501 392 0.125
regulation of tube size GO:0035150 89 0.124
intestinal absorption GO:0050892 3 0.123
lipid biosynthetic process GO:0008610 128 0.122
response to peptide hormone GO:0043434 278 0.119
regulation of blood vessel size GO:0050880 89 0.119
protein maturation GO:0051604 68 0.116
Mouse Rat
brain renin angiotensin system GO:0002035 3 0.115
monocarboxylic acid metabolic process GO:0032787 152 0.112
vascular process in circulatory system GO:0003018 96 0.107
alcohol metabolic process GO:0006066 77 0.103
cellular catabolic process GO:0044248 295 0.102
organic substance catabolic process GO:1901575 316 0.101
proteolysis GO:0006508 175 0.100
Mouse Rat
regulation of apoptotic process GO:0042981 335 0.097
response to oxygen levels GO:0070482 265 0.097
cellular hormone metabolic process GO:0034754 49 0.097
regulation of phosphorylation GO:0042325 248 0.096
Mouse
negative regulation of programmed cell death GO:0043069 183 0.094
intracellular signal transduction GO:0035556 314 0.093
Mouse
response to methanol GO:0033986 1 0.092
response to monosaccharide GO:0034284 159 0.089
negative regulation of metabolic process GO:0009892 331 0.089
Mouse Rat
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.089
response to vitamin GO:0033273 131 0.087
store operated calcium entry GO:0002115 2 0.087
Mouse
regulation of programmed cell death GO:0043067 341 0.087
positive regulation of cell death GO:0010942 184 0.087
cellular response to hormone stimulus GO:0032870 247 0.086
negative regulation of molecular function GO:0044092 133 0.084
Mouse Rat
regulation of cellular component organization GO:0051128 368 0.083
protein phosphorylation GO:0006468 345 0.083
Mouse
positive regulation of secretion by cell GO:1903532 128 0.082
regulation of vesicle mediated transport GO:0060627 81 0.081
Mouse
positive regulation of cellular protein metabolic process GO:0032270 167 0.079
positive regulation of phosphate metabolic process GO:0045937 262 0.078
regulation of intracellular signal transduction GO:1902531 218 0.076
Mouse
lipid catabolic process GO:0016042 46 0.076
positive regulation of phosphorus metabolic process GO:0010562 262 0.076
response to purine containing compound GO:0014074 126 0.076
steroid metabolic process GO:0008202 73 0.075
positive regulation of molecular function GO:0044093 230 0.073
cellular response to cytokine stimulus GO:0071345 127 0.073
response to biotic stimulus GO:0009607 226 0.073
macromolecule localization GO:0033036 252 0.070
aging GO:0007568 241 0.069
regulation of cell proliferation GO:0042127 359 0.069
response to chromate GO:0046687 3 0.068
regulation of system process GO:0044057 208 0.067
regulation of phosphorus metabolic process GO:0051174 349 0.067
Mouse
cation transport GO:0006812 382 0.067
Mouse
regulation of hydrolase activity GO:0051336 143 0.066
Mouse Rat
cellular homeostasis GO:0019725 252 0.065
artery smooth muscle contraction GO:0014824 4 0.064
exogenous drug catabolic process GO:0042738 1 0.063
regulation of extracellular matrix constituent secretion GO:0003330 2 0.062
negative regulation of macromolecule metabolic process GO:0010605 260 0.062
Mouse Rat
positive regulation of biosynthetic process GO:0009891 319 0.061
cellular component biogenesis GO:0044085 368 0.060
response to vitamin b6 GO:0034516 1 0.060
chemical homeostasis GO:0048878 292 0.060
single organism catabolic process GO:0044712 283 0.060
divalent metal ion transport GO:0070838 132 0.060
Mouse
positive regulation of phosphorylation GO:0042327 177 0.060
protein processing GO:0016485 68 0.060
Mouse Rat
negative regulation of cellular metabolic process GO:0031324 281 0.059
Mouse Rat
nitrogen compound transport GO:0071705 229 0.059
homeostatic process GO:0042592 331 0.059
regulation of anatomical structure size GO:0090066 135 0.059
positive regulation of multicellular organismal process GO:0051240 387 0.057
cellular component assembly GO:0022607 360 0.057
response to external biotic stimulus GO:0043207 221 0.057
regulation of cellular ketone metabolic process GO:0010565 27 0.057
secretion by cell GO:0032940 248 0.057
Mouse
cellular amine metabolic process GO:0044106 38 0.056
response to muscle activity involved in regulation of muscle adaptation GO:0014873 2 0.055
cellular response to organonitrogen compound GO:0071417 197 0.055
regulation of signal transduction GO:0009966 318 0.055
Mouse
cellular modified amino acid metabolic process GO:0006575 61 0.055
catabolic process GO:0009056 351 0.054
regulation of hormone secretion GO:0046883 106 0.054
response to organophosphorus GO:0046683 102 0.053
regulation of protein modification process GO:0031399 194 0.052
Mouse
cellular response to mechanical stimulus GO:0071260 48 0.052
hormone transport GO:0009914 121 0.052
regulation of secretion by cell GO:1903530 208 0.052
Mouse
regulation of kinase activity GO:0043549 117 0.052
response to mechanical stimulus GO:0009612 134 0.052
long chain fatty acid transport GO:0015909 14 0.051
tissue development GO:0009888 252 0.051
single organism carbohydrate metabolic process GO:0044723 118 0.050
carbohydrate derivative metabolic process GO:1901135 346 0.050
response to bacterium GO:0009617 200 0.050
establishment of protein localization GO:0045184 141 0.050
wound healing GO:0042060 122 0.049
response to hypoxia GO:0001666 231 0.049
positive regulation of catalytic activity GO:0043085 184 0.049
organ regeneration GO:0031100 101 0.048
positive regulation of cell communication GO:0010647 271 0.048
acute phase response GO:0006953 20 0.048
positive regulation of protein metabolic process GO:0051247 178 0.047
cell projection organization GO:0030030 302 0.047
aromatic amino acid family catabolic process GO:0009074 7 0.047
regulation of cell differentiation GO:0045595 320 0.046
cellular response to external stimulus GO:0071496 118 0.045
negative regulation of gene expression GO:0010629 199 0.045
Mouse Rat
response to decreased oxygen levels GO:0036293 237 0.045
regulation of protein maturation GO:1903317 50 0.044
Mouse Rat
positive regulation of blood circulation GO:1903524 65 0.044
regulation of protein processing GO:0070613 50 0.044
Mouse Rat
phospholipid metabolic process GO:0006644 61 0.044
divalent inorganic cation transport GO:0072511 134 0.044
Mouse
regulation of calcium ion transport GO:0051924 77 0.044
Mouse
alpha amino acid metabolic process GO:1901605 71 0.043
positive regulation of secretion GO:0051047 140 0.043
cellular sodium ion homeostasis GO:0006883 4 0.043
negative regulation of apoptotic process GO:0043066 181 0.042
response to glucose GO:0009749 136 0.042
positive regulation of lipid kinase activity GO:0090218 2 0.042
response to ketone GO:1901654 182 0.041
glycerolipid metabolic process GO:0046486 67 0.041
response to metal ion GO:0010038 253 0.041
negative regulation of peptidase activity GO:0010466 38 0.041
Mouse Rat
positive regulation of extracellular matrix constituent secretion GO:0003331 2 0.041
calcium ion transport GO:0006816 131 0.040
Mouse
response to wounding GO:0009611 254 0.040
response to lipopolysaccharide GO:0032496 191 0.040
c21 steroid hormone biosynthetic process GO:0006700 10 0.040
organic acid biosynthetic process GO:0016053 83 0.039
cellular response to organic cyclic compound GO:0071407 202 0.039
behavior GO:0007610 205 0.039
reproductive process GO:0022414 372 0.039
Mouse
positive regulation of intracellular signal transduction GO:1902533 138 0.039
4 nitrophenol metabolic process GO:0018960 1 0.039
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.039
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.038
response to molecule of bacterial origin GO:0002237 194 0.038
positive regulation of signaling GO:0023056 270 0.038
cellular response to interleukin 1 GO:0071347 37 0.038
regulation of cellular component movement GO:0051270 150 0.038
single organism reproductive process GO:0044702 297 0.037
Mouse
regulation of cellular localization GO:0060341 263 0.037
Mouse
regulation of ion transport GO:0043269 245 0.037
Mouse
catenin import into nucleus GO:0035411 1 0.037
response to alkaloid GO:0043279 132 0.037
cellular chemical homeostasis GO:0055082 247 0.037
purine containing compound metabolic process GO:0072521 253 0.037
anatomical structure morphogenesis GO:0009653 298 0.037
phosphatidylethanolamine metabolic process GO:0046337 1 0.036
chylomicron remodeling GO:0034371 1 0.036
regulation of nervous system development GO:0051960 264 0.035
regulation of multicellular organismal development GO:2000026 376 0.035
cellular lipid catabolic process GO:0044242 37 0.035
response to triglyceride GO:0034014 3 0.035
angiogenesis GO:0001525 53 0.035
regulation of blood pressure GO:0008217 83 0.035
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.035
carbohydrate metabolic process GO:0005975 130 0.034
regulation of secretion GO:0051046 224 0.034
Mouse
cell cell signaling GO:0007267 335 0.034
negative regulation of transport GO:0051051 136 0.034
Mouse
negative regulation of protein metabolic process GO:0051248 114 0.034
Mouse Rat
positive regulation of apoptotic process GO:0043065 154 0.033
immunoglobulin mediated immune response GO:0016064 4 0.033
cellular carbohydrate metabolic process GO:0044262 72 0.033
response to vitamin k GO:0032571 4 0.033
sulfur compound metabolic process GO:0006790 70 0.033
negative regulation of protein processing GO:0010955 47 0.033
Mouse Rat
acute inflammatory response GO:0002526 58 0.033
positive regulation of protein phosphorylation GO:0001934 135 0.033
negative regulation of endopeptidase activity GO:0010951 36 0.033
Mouse Rat
negative regulation of response to stimulus GO:0048585 155 0.033
Mouse
organonitrogen compound biosynthetic process GO:1901566 167 0.032
cellular response to glucocorticoid stimulus GO:0071385 68 0.032
positive regulation of cell proliferation GO:0008284 249 0.032
regulation of rna biosynthetic process GO:2001141 381 0.032
cellular ketone metabolic process GO:0042180 51 0.031
regeneration GO:0031099 163 0.031
positive regulation of phosphatidylinositol 3 kinase activity GO:0043552 2 0.031
signal transduction by phosphorylation GO:0023014 144 0.031
neurological system process GO:0050877 219 0.031
organic cyclic compound catabolic process GO:1901361 175 0.031
hemostasis GO:0007599 26 0.030
positive regulation of transcription dna templated GO:0045893 197 0.030
cellular cation homeostasis GO:0030003 180 0.030
vasoconstriction GO:0042310 54 0.030
negative regulation of proteolysis GO:0045861 41 0.030
Mouse Rat
regulation of hormone levels GO:0010817 187 0.030
organic hydroxy compound metabolic process GO:1901615 115 0.030
response to insulin GO:0032868 133 0.030
regulation of neurogenesis GO:0050767 247 0.030
cofactor metabolic process GO:0051186 95 0.030
aromatic amino acid family metabolic process GO:0009072 9 0.029
alcohol biosynthetic process GO:0046165 38 0.029
aromatic compound catabolic process GO:0019439 168 0.029
regulation of systemic arterial blood pressure GO:0003073 30 0.029
cellular component movement GO:0006928 248 0.029
regulation of synaptic plasticity GO:0048167 70 0.029
negative regulation of catalytic activity GO:0043086 103 0.029
Mouse Rat
tonic smooth muscle contraction GO:0014820 4 0.029
reactive oxygen species biosynthetic process GO:1903409 8 0.028
carbohydrate derivative biosynthetic process GO:1901137 124 0.028
negative regulation of response to external stimulus GO:0032102 37 0.028
ion homeostasis GO:0050801 212 0.028
glucocorticoid metabolic process GO:0008211 7 0.028
lipid localization GO:0010876 62 0.028
response to fatty acid GO:0070542 65 0.027
terpenoid metabolic process GO:0006721 37 0.027
amine metabolic process GO:0009308 38 0.027
immune response GO:0006955 104 0.027
regulation of natural killer cell mediated immune response to tumor cell GO:0002855 1 0.027
regulation of lipid metabolic process GO:0019216 68 0.027
regulation of cell development GO:0060284 263 0.027
regulation of reactive oxygen species biosynthetic process GO:1903426 5 0.027
response to corticosterone GO:0051412 40 0.026
response to transition metal nanoparticle GO:1990267 122 0.026
nucleotide metabolic process GO:0009117 279 0.026
cellular alcohol biosynthetic process GO:0044108 2 0.026
regulation of cellular amino acid metabolic process GO:0006521 2 0.026
nucleic acid templated transcription GO:0097659 379 0.026
cytosolic calcium ion homeostasis GO:0051480 140 0.026
response to acid chemical GO:0001101 222 0.026
regulation of transcription dna templated GO:0006355 374 0.026
muscle system process GO:0003012 115 0.025
protein localization GO:0008104 191 0.025
temperature homeostasis GO:0001659 17 0.025
cellular response to oxygen containing compound GO:1901701 386 0.025
negative regulation of protein maturation GO:1903318 47 0.025
Mouse Rat
macromolecular complex assembly GO:0065003 273 0.025
cell activation GO:0001775 97 0.025
cellular response to lipopolysaccharide GO:0071222 55 0.025
regulation of peptidase activity GO:0052547 55 0.024
Mouse Rat
positive regulation of cellular component organization GO:0051130 200 0.024
regulation of necroptotic process GO:0060544 2 0.024
mapk cascade GO:0000165 140 0.024
metal ion homeostasis GO:0055065 186 0.024
small gtpase mediated signal transduction GO:0007264 36 0.024
lipid transport GO:0006869 61 0.024
circadian rhythm GO:0007623 88 0.024
peptide hormone secretion GO:0030072 84 0.023
endothelial cell apoptotic process GO:0072577 3 0.023
insecticide metabolic process GO:0017143 4 0.023
response to cadmium ion GO:0046686 35 0.023
macromolecular complex subunit organization GO:0043933 339 0.023
organic acid catabolic process GO:0016054 49 0.023
small molecule catabolic process GO:0044282 59 0.023
protein complex subunit organization GO:0071822 302 0.023
regulation of protein phosphorylation GO:0001932 183 0.023
Mouse
fat soluble vitamin biosynthetic process GO:0042362 2 0.023
negative regulation of cellular protein metabolic process GO:0032269 106 0.023
Mouse Rat
heart morphogenesis GO:0003007 3 0.023
regulation of response to stress GO:0080134 126 0.022
response to estradiol GO:0032355 164 0.022
positive regulation of programmed cell death GO:0043068 157 0.022
vesicle mediated transport GO:0016192 181 0.022
Mouse
necroptotic process GO:0070266 2 0.022
progesterone metabolic process GO:0042448 8 0.022
reactive nitrogen species metabolic process GO:2001057 1 0.021
response to acetate GO:0010034 3 0.021
neuron projection development GO:0031175 273 0.021
olfactory behavior GO:0042048 2 0.021
reactive oxygen species metabolic process GO:0072593 37 0.021
multicellular organism reproduction GO:0032504 233 0.021
halogenated hydrocarbon metabolic process GO:0042197 4 0.021
regulation of blood circulation GO:1903522 110 0.021
positive regulation of gene expression GO:0010628 244 0.021
cellular metal ion homeostasis GO:0006875 172 0.021
regulation of vasoconstriction GO:0019229 44 0.020
purine ribonucleotide metabolic process GO:0009150 227 0.020
regulation of catabolic process GO:0009894 113 0.020
cellular response to alcohol GO:0097306 87 0.020
organophosphate biosynthetic process GO:0090407 143 0.020
positive regulation of transferase activity GO:0051347 81 0.020
single organism nuclear import GO:1902593 35 0.020
cellular response to peptide hormone stimulus GO:0071375 120 0.020
coenzyme metabolic process GO:0006732 86 0.020
sulfur compound biosynthetic process GO:0044272 19 0.020
protein complex assembly GO:0006461 263 0.020
cellular macromolecule localization GO:0070727 122 0.020
cellular response to abiotic stimulus GO:0071214 85 0.020
vitamin d metabolic process GO:0042359 4 0.020
response to interleukin 1 GO:0070555 55 0.020
oxidation reduction process GO:0055114 304 0.020
b cell mediated immunity GO:0019724 4 0.019
regulation of wound healing GO:0061041 14 0.019
regulation of cellular amine metabolic process GO:0033238 8 0.019
response to vitamin a GO:0033189 36 0.019
metal ion transport GO:0030001 289 0.019
Mouse
cellular response to nitrogen compound GO:1901699 210 0.019
locomotion GO:0040011 237 0.019
central nervous system development GO:0007417 311 0.019
cellular response to hydroperoxide GO:0071447 2 0.019
regulation of transferase activity GO:0051338 123 0.019
regulation of immunoglobulin mediated immune response GO:0002889 2 0.019
immune system process GO:0002376 204 0.019
apoptotic signaling pathway GO:0097190 27 0.019
positive regulation of response to stimulus GO:0048584 285 0.019
natural killer cell mediated immune response to tumor cell GO:0002423 1 0.019
negative regulation of immune system process GO:0002683 39 0.019
growth GO:0040007 165 0.019
endocrine process GO:0050886 32 0.018
gonad development GO:0008406 104 0.018
secondary alcohol metabolic process GO:1902652 2 0.018
fertilization GO:0009566 3 0.018
Mouse
regulation of endopeptidase activity GO:0052548 51 0.018
Mouse Rat
organic hydroxy compound biosynthetic process GO:1901617 51 0.018
cellular response to glucose stimulus GO:0071333 65 0.018
cellular response to vitamin k GO:0071307 1 0.018
cellular biogenic amine metabolic process GO:0006576 30 0.018
renal system development GO:0072001 67 0.018
response to insecticide GO:0017085 21 0.018
digestion GO:0007586 26 0.018
leukocyte cell cell adhesion GO:0007159 4 0.017
regulation of neuron projection development GO:0010975 161 0.017
secretion GO:0046903 307 0.017
Mouse
striated muscle tissue development GO:0014706 58 0.017
isoprenoid metabolic process GO:0006720 45 0.017
glycosyl compound metabolic process GO:1901657 182 0.017
digestive system process GO:0022600 24 0.017
response to other organism GO:0051707 220 0.017
developmental growth GO:0048589 100 0.017
organonitrogen compound catabolic process GO:1901565 179 0.017
cellular calcium ion homeostasis GO:0006874 160 0.017
cytoplasmic transport GO:0016482 115 0.017
regulation of proteolysis GO:0030162 66 0.017
Mouse Rat
response to dexamethasone GO:0071548 49 0.016
positive regulation of cellular amine metabolic process GO:0033240 3 0.016
positive regulation of protein modification process GO:0031401 142 0.016
chlorinated hydrocarbon metabolic process GO:0042196 4 0.016
toxin catabolic process GO:0009407 1 0.016
biphenyl metabolic process GO:0018879 10 0.016
positive regulation of kinase activity GO:0033674 77 0.016
nucleobase containing small molecule metabolic process GO:0055086 316 0.016
negative regulation of natural killer cell mediated cytotoxicity directed against tumor cell target GO:0002859 1 0.016
negative regulation of endothelial cell proliferation GO:0001937 5 0.016
intracellular transport GO:0046907 185 0.016
cellular ion homeostasis GO:0006873 184 0.016
response to camp GO:0051591 91 0.016
response to nicotine GO:0035094 51 0.016
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.016
protein complex biogenesis GO:0070271 263 0.016
localization of cell GO:0051674 202 0.016
renin angiotensin regulation of aldosterone production GO:0002018 3 0.016
response to ddt GO:0046680 1 0.016
response to amino acid GO:0043200 75 0.016
purine containing compound catabolic process GO:0072523 138 0.016
positive regulation of rna metabolic process GO:0051254 203 0.016
carboxylic acid catabolic process GO:0046395 49 0.016
muscle contraction GO:0006936 88 0.016
positive regulation of rna biosynthetic process GO:1902680 197 0.016
positive regulation of necrotic cell death GO:0010940 4 0.015
extracellular matrix organization GO:0030198 13 0.015
regulation of reactive oxygen species metabolic process GO:2000377 26 0.015
glucocorticoid biosynthetic process GO:0006704 5 0.015
g protein coupled receptor signaling pathway GO:0007186 242 0.015
cellular response to stress GO:0033554 269 0.015
monocarboxylic acid biosynthetic process GO:0072330 48 0.015
regulation of carbohydrate metabolic process GO:0006109 41 0.015
c21 steroid hormone metabolic process GO:0008207 14 0.015
positive regulation of nucleic acid templated transcription GO:1903508 197 0.015
response to ammonium ion GO:0060359 71 0.015
acylglycerol biosynthetic process GO:0046463 7 0.015
cardiovascular system development GO:0072358 134 0.015
organic hydroxy compound transport GO:0015850 77 0.015
cellular response to oxidative stress GO:0034599 76 0.015
estrogen metabolic process GO:0008210 11 0.015
single organism organelle organization GO:1902589 180 0.015
sexual reproduction GO:0019953 148 0.015
Mouse
negative regulation of cell communication GO:0010648 158 0.015
Mouse
response to activity GO:0014823 73 0.015
exocytosis GO:0006887 60 0.015
Mouse
ribose phosphate metabolic process GO:0019693 235 0.015
acrosome assembly GO:0001675 3 0.014
protein homooligomerization GO:0051260 91 0.014
cellular response to camp GO:0071320 26 0.014
positive regulation of lipid metabolic process GO:0045834 33 0.014
regulation of response to external stimulus GO:0032101 106 0.014
vitamin d3 metabolic process GO:0070640 2 0.014
protein transport GO:0015031 132 0.014
indole containing compound metabolic process GO:0042430 11 0.014
multi multicellular organism process GO:0044706 138 0.014
ribonucleotide metabolic process GO:0009259 231 0.014
programmed necrotic cell death GO:0097300 2 0.014
vitamin biosynthetic process GO:0009110 3 0.014
multicellular organismal reproductive process GO:0048609 233 0.014
ribonucleotide biosynthetic process GO:0009260 85 0.014
positive regulation of t cell chemotaxis GO:0010820 1 0.014
regulation of cell projection organization GO:0031344 175 0.014
development of primary female sexual characteristics GO:0046545 56 0.014
blood vessel morphogenesis GO:0048514 58 0.014
positive regulation of cellular catabolic process GO:0031331 71 0.014
bone development GO:0060348 25 0.014
olfactory learning GO:0008355 1 0.014
negative regulation of uterine smooth muscle contraction GO:0070473 2 0.014
positive regulation of reactive oxygen species biosynthetic process GO:1903428 2 0.014
regulation of transporter activity GO:0032409 50 0.014
multicellular organismal homeostasis GO:0048871 49 0.014
response to prostaglandin GO:0034694 16 0.014
signal release GO:0023061 145 0.013
positive regulation of homeostatic process GO:0032846 49 0.013
regulation of protein kinase activity GO:0045859 105 0.013
regulation of vasodilation GO:0042312 36 0.013
multi organism reproductive process GO:0044703 262 0.013
Mouse
response to mineralocorticoid GO:0051385 49 0.013
single organism cellular localization GO:1902580 102 0.013
protein secretion GO:0009306 34 0.013
regulation of homeostatic process GO:0032844 101 0.013
nucleocytoplasmic transport GO:0006913 48 0.013
rhythmic process GO:0048511 156 0.013
amide transport GO:0042886 105 0.013
negative regulation of signaling GO:0023057 157 0.013
Mouse
regulation of cellular carbohydrate metabolic process GO:0010675 39 0.013
phthalate metabolic process GO:0018963 8 0.013
positive regulation of fatty acid beta oxidation GO:0032000 4 0.013
response to food GO:0032094 27 0.013
purine containing compound biosynthetic process GO:0072522 85 0.013
positive regulation of transmembrane transport GO:0034764 25 0.013
vitamin d biosynthetic process GO:0042368 2 0.013
response to testosterone GO:0033574 55 0.013
regulation of neuron differentiation GO:0045664 208 0.013
response to hexose GO:0009746 144 0.013
estrogen catabolic process GO:0006711 1 0.013
rna metabolic process GO:0016070 406 0.013
negative regulation of cellular component organization GO:0051129 83 0.013
ion transmembrane transport GO:0034220 365 0.013
Mouse
peptide transport GO:0015833 97 0.013
anatomical structure formation involved in morphogenesis GO:0048646 83 0.012
regulation of calcium ion dependent exocytosis GO:0017158 11 0.012
Mouse
gamete generation GO:0007276 124 0.012
organelle organization GO:0006996 266 0.012
negative regulation of hydrolase activity GO:0051346 52 0.012
Mouse Rat
negative regulation of natural killer cell mediated immune response to tumor cell GO:0002856 1 0.012
regulation of nucleic acid templated transcription GO:1903506 380 0.012
regulation of rna metabolic process GO:0051252 391 0.012
hexose metabolic process GO:0019318 58 0.012
regulation of vasculature development GO:1901342 44 0.012
erk1 and erk2 cascade GO:0070371 48 0.012
positive regulation of hydrolase activity GO:0051345 86 0.012
positive regulation of reactive oxygen species metabolic process GO:2000379 16 0.012
acetyl coa metabolic process GO:0006084 17 0.012
negative regulation of cell proliferation GO:0008285 119 0.012
carbohydrate homeostasis GO:0033500 75 0.012
regulation of ion transmembrane transport GO:0034765 121 0.012
Mouse
hormone metabolic process GO:0042445 69 0.012
cellular nitrogen compound catabolic process GO:0044270 163 0.012
transcription from rna polymerase ii promoter GO:0006366 252 0.012
cellular response to carbohydrate stimulus GO:0071322 72 0.012
benzene containing compound metabolic process GO:0042537 22 0.012

Spink1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.038
vascular disease DOID:178 0 0.038
cardiovascular system disease DOID:1287 0 0.038
artery disease DOID:0050828 0 0.036
disease of metabolism DOID:0014667 0 0.022
hypertension DOID:10763 0 0.017
essential hypertension DOID:10825 0 0.017
substance related disorder DOID:303 0 0.017
disease of mental health DOID:150 0 0.017