Rattus norvegicus

19 known processes

H3f3b

H3 histone, family 3B

(Aliases: H3.3B,MGC105794)

H3f3b biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
alternative mrna splicing via spliceosome GO:0000380 4 0.345
regulation of alternative mrna splicing via spliceosome GO:0000381 2 0.313
organelle organization GO:0006996 266 0.162
regulation of mrna splicing via spliceosome GO:0048024 3 0.159
rna metabolic process GO:0016070 406 0.142
negative regulation of rna metabolic process GO:0051253 123 0.116
positive regulation of hydrolase activity GO:0051345 86 0.114
neuron development GO:0048666 286 0.110
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.110
regulation of apoptotic process GO:0042981 335 0.105
reproduction GO:0000003 245 0.104
regulation of catalytic activity GO:0050790 304 0.099
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.098
aromatic compound catabolic process GO:0019439 168 0.096
positive regulation of gene expression GO:0010628 244 0.094
multicellular organismal reproductive process GO:0048609 233 0.092
cytoskeleton organization GO:0007010 111 0.089
negative regulation of metabolic process GO:0009892 331 0.089
multi organism reproductive process GO:0044703 262 0.087
regulation of molecular function GO:0065009 398 0.085
mrna metabolic process GO:0016071 20 0.079
positive regulation of biosynthetic process GO:0009891 319 0.074
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.073
negative regulation of gene expression GO:0010629 199 0.073
mrna processing GO:0006397 14 0.073
reproductive process GO:0022414 372 0.071
regulation of rna splicing GO:0043484 6 0.069
regulation of hydrolase activity GO:0051336 143 0.068
single organism organelle organization GO:1902589 180 0.068
multicellular organism reproduction GO:0032504 233 0.067
cellular response to oxygen containing compound GO:1901701 386 0.065
cellular component assembly GO:0022607 360 0.063
nucleic acid templated transcription GO:0097659 379 0.059
sexual reproduction GO:0019953 148 0.058
negative regulation of programmed cell death GO:0043069 183 0.056
regulation of programmed cell death GO:0043067 341 0.054
organic substance catabolic process GO:1901575 316 0.052
neuron differentiation GO:0030182 368 0.047
anterior posterior pattern specification GO:0009952 1 0.047
developmental process involved in reproduction GO:0003006 159 0.045
regulation of rna metabolic process GO:0051252 391 0.045
erythrocyte differentiation GO:0030218 1 0.043
positive regulation of catalytic activity GO:0043085 184 0.042
organic cyclic compound catabolic process GO:1901361 175 0.042
positive regulation of cellular biosynthetic process GO:0031328 295 0.042
negative regulation of cell communication GO:0010648 158 0.042
positive regulation of multicellular organismal process GO:0051240 387 0.041
nucleobase containing compound catabolic process GO:0034655 152 0.041
regulation of multicellular organismal development GO:2000026 376 0.041
purine ribonucleotide metabolic process GO:0009150 227 0.041
transcription dna templated GO:0006351 377 0.041
negative regulation of cellular metabolic process GO:0031324 281 0.040
regulation of cellular protein metabolic process GO:0032268 267 0.039
cellular catabolic process GO:0044248 295 0.039
regulation of mrna processing GO:0050684 5 0.038
heterocycle catabolic process GO:0046700 167 0.037
negative regulation of apoptotic process GO:0043066 181 0.037
regulation of cell development GO:0060284 263 0.034
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.034
purine nucleotide catabolic process GO:0006195 136 0.034
circulatory system development GO:0072359 134 0.034
gamete generation GO:0007276 124 0.033
regulation of rna biosynthetic process GO:2001141 381 0.032
cardiac muscle contraction GO:0060048 27 0.032
negative regulation of cell death GO:0060548 229 0.032
rna processing GO:0006396 22 0.031
negative regulation of rna biosynthetic process GO:1902679 118 0.031
nucleoside phosphate metabolic process GO:0006753 283 0.031
cellular component biogenesis GO:0044085 368 0.030
positive regulation of molecular function GO:0044093 230 0.030
cell type specific apoptotic process GO:0097285 134 0.030
regulation of cellular component organization GO:0051128 368 0.030
neuron apoptotic process GO:0051402 88 0.030
rna splicing via transesterification reactions GO:0000375 7 0.029
protein complex assembly GO:0006461 263 0.029
cellular nitrogen compound catabolic process GO:0044270 163 0.028
purine ribonucleotide catabolic process GO:0009154 136 0.028
negative regulation of rna splicing GO:0033119 3 0.028
regulation of protein metabolic process GO:0051246 289 0.028
rna splicing GO:0008380 11 0.028
sex determination GO:0007530 2 0.027
response to wounding GO:0009611 254 0.027
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.027
response to peptide hormone GO:0043434 278 0.027
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.027
purine nucleoside metabolic process GO:0042278 169 0.026
regulation of hormone secretion GO:0046883 106 0.025
embryonic axis specification GO:0000578 1 0.025
mrna stabilization GO:0048255 2 0.025
positive regulation of nucleotide metabolic process GO:0045981 91 0.024
negative regulation of catalytic activity GO:0043086 103 0.024
negative regulation of macromolecule metabolic process GO:0010605 260 0.024
negative regulation of molecular function GO:0044092 133 0.024
spermatogenesis GO:0007283 99 0.024
neuron death GO:0070997 127 0.024
cellular component morphogenesis GO:0032989 155 0.024
negative regulation of signaling GO:0023057 157 0.024
apoptotic process GO:0006915 381 0.023
nitrogen compound transport GO:0071705 229 0.023
vasculature development GO:0001944 70 0.023
circulatory system process GO:0003013 183 0.022
embryonic pattern specification GO:0009880 1 0.022
anatomical structure morphogenesis GO:0009653 298 0.022
male sex differentiation GO:0046661 64 0.022
negative regulation of protein metabolic process GO:0051248 114 0.022
heart contraction GO:0060047 57 0.022
single organism reproductive process GO:0044702 297 0.022
positive regulation of cell differentiation GO:0045597 217 0.022
amine metabolic process GO:0009308 38 0.022
positive regulation of transcription dna templated GO:0045893 197 0.021
macromolecular complex subunit organization GO:0043933 339 0.021
single organism cellular localization GO:1902580 102 0.021
aging GO:0007568 241 0.021
response to oxidative stress GO:0006979 186 0.021
rna localization GO:0006403 4 0.021
regulation of cell differentiation GO:0045595 320 0.021
response to inorganic substance GO:0010035 377 0.020
chemical homeostasis GO:0048878 292 0.020
protein complex biogenesis GO:0070271 263 0.020
hematopoietic progenitor cell differentiation GO:0002244 2 0.020
cellular response to organic cyclic compound GO:0071407 202 0.020
regulation of cellular localization GO:0060341 263 0.019
neuron projection development GO:0031175 273 0.019
positive regulation of rna metabolic process GO:0051254 203 0.019
vesicle mediated transport GO:0016192 181 0.019
nucleoside phosphate catabolic process GO:1901292 140 0.019
purine nucleoside triphosphate metabolic process GO:0009144 141 0.019
regulation of nucleic acid templated transcription GO:1903506 380 0.019
regulation of transcription dna templated GO:0006355 374 0.019
regulation of nucleotide metabolic process GO:0006140 117 0.019
rhythmic process GO:0048511 156 0.019
regulation of endothelial cell differentiation GO:0045601 4 0.018
positive regulation of programmed cell death GO:0043068 157 0.018
reproductive structure development GO:0048608 128 0.018
purine ribonucleoside triphosphate metabolic process GO:0009205 140 0.018
purine ribonucleoside metabolic process GO:0046128 168 0.018
macromolecule localization GO:0033036 252 0.018
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.018
circadian rhythm GO:0007623 88 0.017
purine nucleotide metabolic process GO:0006163 229 0.017
cellular response to peptide GO:1901653 133 0.017
cell junction organization GO:0034330 21 0.017
negative regulation of neuron death GO:1901215 69 0.017
regulation of neuron death GO:1901214 115 0.017
protein localization GO:0008104 191 0.017
regulation of cellular amino acid metabolic process GO:0006521 2 0.017
cell cycle process GO:0022402 57 0.017
homeostatic process GO:0042592 331 0.016
intracellular signal transduction GO:0035556 314 0.016
cell projection organization GO:0030030 302 0.016
nucleoside triphosphate catabolic process GO:0009143 123 0.016
positive regulation of protein metabolic process GO:0051247 178 0.016
positive regulation of cellular component organization GO:0051130 200 0.016
protein processing GO:0016485 68 0.016
negative regulation of response to stimulus GO:0048585 155 0.016
protein complex subunit organization GO:0071822 302 0.016
male gamete generation GO:0048232 99 0.015
regulation of neuron projection development GO:0010975 161 0.015
regulation of nucleoside metabolic process GO:0009118 66 0.015
macromolecular complex assembly GO:0065003 273 0.015
cardiovascular system development GO:0072358 134 0.015
chemotaxis GO:0006935 66 0.015
developmental maturation GO:0021700 25 0.015
dna metabolic process GO:0006259 96 0.015
programmed cell death GO:0012501 392 0.015
sex differentiation GO:0007548 113 0.015
ribose phosphate metabolic process GO:0019693 235 0.015
brain development GO:0007420 247 0.015
purine nucleoside catabolic process GO:0006152 124 0.015
erythrocyte homeostasis GO:0034101 2 0.015
mitotic spindle organization GO:0007052 2 0.015
ribonucleotide metabolic process GO:0009259 231 0.015
male gonad development GO:0008584 59 0.015
striated muscle cell development GO:0055002 26 0.015
rna splicing via transesterification reactions with bulged adenosine as nucleophile GO:0000377 7 0.015
development of primary male sexual characteristics GO:0046546 59 0.015
ion homeostasis GO:0050801 212 0.015
response to extracellular stimulus GO:0009991 380 0.015
female gonad development GO:0008585 53 0.014
regulation of purine nucleotide metabolic process GO:1900542 115 0.014
nucleobase containing small molecule metabolic process GO:0055086 316 0.014
multicellular organism growth GO:0035264 1 0.014
cellular response to nitrogen compound GO:1901699 210 0.014
positive regulation of rna biosynthetic process GO:1902680 197 0.014
meiotic chromosome segregation GO:0045132 1 0.014
regulation of cell proliferation GO:0042127 359 0.014
regulation of neuron differentiation GO:0045664 208 0.014
regulation of nucleotide catabolic process GO:0030811 65 0.014
protein oligomerization GO:0051259 191 0.014
positive regulation of cellular amine metabolic process GO:0033240 3 0.014
response to electrical stimulus GO:0051602 56 0.014
response to peptide GO:1901652 292 0.014
cell motility GO:0048870 202 0.014
organonitrogen compound catabolic process GO:1901565 179 0.013
cellular amine metabolic process GO:0044106 38 0.013
organic acid metabolic process GO:0006082 292 0.013
negative regulation of cellular protein metabolic process GO:0032269 106 0.013
carbohydrate derivative metabolic process GO:1901135 346 0.013
positive regulation of developmental process GO:0051094 283 0.013
viral genome replication GO:0019079 2 0.013
positive regulation of mesenchymal cell proliferation GO:0002053 4 0.012
regulation of phosphorus metabolic process GO:0051174 349 0.012
transmembrane transport GO:0055085 412 0.012
positive regulation of nucleic acid templated transcription GO:1903508 197 0.012
signal release GO:0023061 145 0.012
regulation of cellular amine metabolic process GO:0033238 8 0.012
negative regulation of transport GO:0051051 136 0.012
hormone transport GO:0009914 121 0.012
blood circulation GO:0008015 183 0.012
calcium ion transport GO:0006816 131 0.012
ribonucleoside triphosphate catabolic process GO:0009203 122 0.012
regulation of mesenchymal cell proliferation GO:0010464 4 0.012
regulation of body fluid levels GO:0050878 90 0.012
cell migration GO:0016477 197 0.012
nucleoside triphosphate metabolic process GO:0009141 144 0.012
cellular response to insulin stimulus GO:0032869 81 0.012
transcription from rna polymerase ii promoter GO:0006366 252 0.012
regulation of embryonic development GO:0045995 2 0.011
positive regulation of cellular protein metabolic process GO:0032270 167 0.011
positive regulation of neuron differentiation GO:0045666 126 0.011
neuron projection morphogenesis GO:0048812 122 0.011
ion transmembrane transport GO:0034220 365 0.011
cellular response to organonitrogen compound GO:0071417 197 0.011
response to reactive oxygen species GO:0000302 120 0.011
regulation of signal transduction GO:0009966 318 0.011
cellular process involved in reproduction in multicellular organism GO:0022412 35 0.011
cellular chemical homeostasis GO:0055082 247 0.011
ribonucleoprotein complex biogenesis GO:0022613 10 0.011
protein homooligomerization GO:0051260 91 0.011
biological adhesion GO:0022610 110 0.011
ribonucleoside catabolic process GO:0042454 126 0.011
positive regulation of neuron projection development GO:0010976 99 0.011
catabolic process GO:0009056 351 0.011
ribonucleoside triphosphate metabolic process GO:0009199 141 0.011
secretion GO:0046903 307 0.010
cellular response to endogenous stimulus GO:0071495 377 0.010
anion transport GO:0006820 178 0.010
cell activation GO:0001775 97 0.010
g protein coupled receptor signaling pathway GO:0007186 242 0.010
immune response GO:0006955 104 0.010
striated muscle contraction GO:0006941 44 0.010
response to metal ion GO:0010038 253 0.010
regulation of viral genome replication GO:0045069 2 0.010
positive regulation of purine nucleotide metabolic process GO:1900544 91 0.010
anatomical structure formation involved in morphogenesis GO:0048646 83 0.010
atp dependent chromatin remodeling GO:0043044 1 0.010
negative regulation of cell proliferation GO:0008285 119 0.010
positive regulation of cell proliferation GO:0008284 249 0.010
regulation of peptidase activity GO:0052547 55 0.010
regulation of endopeptidase activity GO:0052548 51 0.010
localization of cell GO:0051674 202 0.010
cellular component movement GO:0006928 248 0.010

H3f3b disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
myopathy DOID:423 0 0.017
muscular disease DOID:0080000 0 0.017
disease of anatomical entity DOID:7 0 0.017
musculoskeletal system disease DOID:17 0 0.017
muscle tissue disease DOID:66 0 0.017