Rattus norvegicus

82 known processes

Bche

butyrylcholinesterase

Bche biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
organic acid metabolic process GO:0006082 292 0.252
carboxylic acid metabolic process GO:0019752 289 0.198
oxoacid metabolic process GO:0043436 290 0.198
cellular response to endogenous stimulus GO:0071495 377 0.126
macromolecule localization GO:0033036 252 0.124
monocarboxylic acid metabolic process GO:0032787 152 0.111
response to nutrient levels GO:0031667 370 0.099
regulation of phosphate metabolic process GO:0019220 349 0.095
single organism biosynthetic process GO:0044711 342 0.093
regulation of phosphorylation GO:0042325 248 0.089
regulation of multicellular organismal development GO:2000026 376 0.088
anatomical structure morphogenesis GO:0009653 298 0.084
protein phosphorylation GO:0006468 345 0.080
cellular lipid metabolic process GO:0044255 208 0.077
cell adhesion GO:0007155 110 0.076
regulation of nucleic acid templated transcription GO:1903506 380 0.076
chemical homeostasis GO:0048878 292 0.074
cellular component movement GO:0006928 248 0.074
protein complex assembly GO:0006461 263 0.072
positive regulation of cell communication GO:0010647 271 0.072
lipid metabolic process GO:0006629 283 0.064
nitrogen compound transport GO:0071705 229 0.062
macromolecular complex assembly GO:0065003 273 0.060
positive regulation of biosynthetic process GO:0009891 319 0.059
positive regulation of catalytic activity GO:0043085 184 0.059
single organism catabolic process GO:0044712 283 0.059
small molecule biosynthetic process GO:0044283 124 0.057
carboxylic acid transport GO:0046942 115 0.056
carboxylic acid biosynthetic process GO:0046394 83 0.055
response to wounding GO:0009611 254 0.054
positive regulation of cell proliferation GO:0008284 249 0.054
positive regulation of phosphorylation GO:0042327 177 0.053
protein complex biogenesis GO:0070271 263 0.053
positive regulation of multicellular organismal process GO:0051240 387 0.052
organophosphate metabolic process GO:0019637 370 0.052
anion transport GO:0006820 178 0.051
nucleic acid templated transcription GO:0097659 379 0.050
positive regulation of molecular function GO:0044093 230 0.050
positive regulation of phosphorus metabolic process GO:0010562 262 0.050
cellular response to oxygen containing compound GO:1901701 386 0.049
regulation of catalytic activity GO:0050790 304 0.049
regulation of molecular function GO:0065009 398 0.048
regulation of cellular ketone metabolic process GO:0010565 27 0.048
regulation of cell proliferation GO:0042127 359 0.048
cellular ketone metabolic process GO:0042180 51 0.047
protein oligomerization GO:0051259 191 0.047
establishment of protein localization GO:0045184 141 0.047
regulation of phosphorus metabolic process GO:0051174 349 0.047
positive regulation of response to stimulus GO:0048584 285 0.046
homeostatic process GO:0042592 331 0.045
positive regulation of transport GO:0051050 245 0.044
cardiac muscle cell contraction GO:0086003 10 0.044
coenzyme metabolic process GO:0006732 86 0.044
positive regulation of cellular amine metabolic process GO:0033240 3 0.044
lipid biosynthetic process GO:0008610 128 0.043
positive regulation of cellular biosynthetic process GO:0031328 295 0.043
positive regulation of signaling GO:0023056 270 0.042
protein localization GO:0008104 191 0.042
positive regulation of phosphate metabolic process GO:0045937 262 0.042
fatty acid metabolic process GO:0006631 99 0.042
cellular response to stress GO:0033554 269 0.042
amine metabolic process GO:0009308 38 0.042
intracellular signal transduction GO:0035556 314 0.041
single organism carbohydrate metabolic process GO:0044723 118 0.040
response to peptide hormone GO:0043434 278 0.039
positive regulation of cellular protein metabolic process GO:0032270 167 0.039
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.038
nucleobase containing small molecule metabolic process GO:0055086 316 0.038
positive regulation of protein metabolic process GO:0051247 178 0.038
cellular component assembly GO:0022607 360 0.038
positive regulation of cell development GO:0010720 176 0.038
rna metabolic process GO:0016070 406 0.038
organic anion transport GO:0015711 132 0.038
macromolecular complex subunit organization GO:0043933 339 0.038
alcohol metabolic process GO:0006066 77 0.037
lipid transport GO:0006869 61 0.037
cellular amino acid metabolic process GO:0006520 107 0.036
regulation of protein phosphorylation GO:0001932 183 0.036
positive regulation of developmental process GO:0051094 283 0.036
response to inorganic substance GO:0010035 377 0.036
organic substance catabolic process GO:1901575 316 0.035
regulation of cellular protein metabolic process GO:0032268 267 0.035
peptidyl amino acid modification GO:0018193 126 0.035
regulation of protein metabolic process GO:0051246 289 0.034
cellular response to nitrogen compound GO:1901699 210 0.034
regulation of protein modification process GO:0031399 194 0.034
cation transmembrane transport GO:0098655 263 0.034
catabolic process GO:0009056 351 0.033
positive regulation of cell differentiation GO:0045597 217 0.033
regulation of rna metabolic process GO:0051252 391 0.033
cellular response to external stimulus GO:0071496 118 0.033
reactive oxygen species metabolic process GO:0072593 37 0.032
cellular amine metabolic process GO:0044106 38 0.032
regulation of response to stress GO:0080134 126 0.032
biological adhesion GO:0022610 110 0.032
vitamin a metabolic process GO:0006776 2 0.032
regulation of cellular component organization GO:0051128 368 0.032
retinal metabolic process GO:0042574 3 0.031
response to extracellular stimulus GO:0009991 380 0.031
response to peptide GO:1901652 292 0.030
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.030
regulation of neurogenesis GO:0050767 247 0.030
immune system process GO:0002376 204 0.030
regulation of cell differentiation GO:0045595 320 0.030
response to growth factor GO:0070848 189 0.030
positive regulation of nucleic acid templated transcription GO:1903508 197 0.029
organic acid biosynthetic process GO:0016053 83 0.029
neuron differentiation GO:0030182 368 0.029
transcription dna templated GO:0006351 377 0.029
regulation of cellular amino acid metabolic process GO:0006521 2 0.029
regulation of cellular amine metabolic process GO:0033238 8 0.028
negative regulation of metabolic process GO:0009892 331 0.028
cellular catabolic process GO:0044248 295 0.028
organelle organization GO:0006996 266 0.028
cofactor metabolic process GO:0051186 95 0.028
urogenital system development GO:0001655 78 0.028
regulation of system process GO:0044057 208 0.028
transmembrane transport GO:0055085 412 0.028
positive regulation of signal transduction GO:0009967 175 0.027
response to metal ion GO:0010038 253 0.027
regulation of protein kinase activity GO:0045859 105 0.027
metal ion transport GO:0030001 289 0.027
positive regulation of protein phosphorylation GO:0001934 135 0.026
b cell activation involved in immune response GO:0002312 1 0.025
carbohydrate metabolic process GO:0005975 130 0.025
non canonical wnt signaling pathway GO:0035567 3 0.025
cell cell signaling GO:0007267 335 0.025
organophosphate biosynthetic process GO:0090407 143 0.025
protein transport GO:0015031 132 0.025
cellular modified amino acid metabolic process GO:0006575 61 0.025
regulation of apoptotic process GO:0042981 335 0.025
circadian regulation of gene expression GO:0032922 3 0.025
unsaturated fatty acid metabolic process GO:0033559 39 0.025
cellular metal ion homeostasis GO:0006875 172 0.025
positive regulation of map kinase activity GO:0043406 46 0.024
positive regulation of rna metabolic process GO:0051254 203 0.024
purine nucleoside metabolic process GO:0042278 169 0.024
cellular response to organonitrogen compound GO:0071417 197 0.023
liver development GO:0001889 90 0.023
monovalent inorganic cation transport GO:0015672 172 0.023
purine ribonucleotide catabolic process GO:0009154 136 0.023
positive regulation of intracellular signal transduction GO:1902533 138 0.023
rna biosynthetic process GO:0032774 380 0.023
apoptotic process GO:0006915 381 0.023
negative regulation of response to stimulus GO:0048585 155 0.022
cellular component biogenesis GO:0044085 368 0.022
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.022
fatty acid oxidation GO:0019395 29 0.022
multicellular organism reproduction GO:0032504 233 0.022
ion homeostasis GO:0050801 212 0.022
wnt signaling pathway calcium modulating pathway GO:0007223 1 0.022
single organism organelle organization GO:1902589 180 0.022
regulation of transcription dna templated GO:0006355 374 0.021
carbohydrate derivative metabolic process GO:1901135 346 0.021
positive regulation of cellular component organization GO:0051130 200 0.021
cytokine biosynthetic process GO:0042089 3 0.021
nucleoside phosphate metabolic process GO:0006753 283 0.021
regulation of transferase activity GO:0051338 123 0.021
monosaccharide metabolic process GO:0005996 61 0.021
protein homooligomerization GO:0051260 91 0.021
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.021
transcription from rna polymerase ii promoter GO:0006366 252 0.021
regulation of cell projection organization GO:0031344 175 0.021
positive regulation of kinase activity GO:0033674 77 0.021
inner medullary collecting duct development GO:0072061 1 0.021
cellular carbohydrate metabolic process GO:0044262 72 0.021
regulation of mapk cascade GO:0043408 116 0.021
fatty acid derivative metabolic process GO:1901568 38 0.020
single organism cellular localization GO:1902580 102 0.020
positive regulation of cell death GO:0010942 184 0.020
cation transport GO:0006812 382 0.020
nucleotide metabolic process GO:0009117 279 0.020
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.020
response to oxygen levels GO:0070482 265 0.020
protein complex subunit organization GO:0071822 302 0.020
locomotion GO:0040011 237 0.020
cell projection organization GO:0030030 302 0.019
head development GO:0060322 247 0.019
smooth muscle cell proliferation GO:0048659 77 0.019
vesicle mediated transport GO:0016192 181 0.019
positive regulation of protein modification process GO:0031401 142 0.019
divalent inorganic cation homeostasis GO:0072507 165 0.019
positive regulation of protein serine threonine kinase activity GO:0071902 52 0.019
regulation of rna biosynthetic process GO:2001141 381 0.019
organ regeneration GO:0031100 101 0.019
tissue development GO:0009888 252 0.019
cellular component morphogenesis GO:0032989 155 0.019
reproduction GO:0000003 245 0.019
programmed cell death GO:0012501 392 0.019
icosanoid metabolic process GO:0006690 38 0.019
cellular response to extracellular stimulus GO:0031668 73 0.019
reproductive process GO:0022414 372 0.018
response to carbohydrate GO:0009743 183 0.018
cellular response to nutrient levels GO:0031669 60 0.018
cellular response to growth factor stimulus GO:0071363 162 0.018
neuron projection development GO:0031175 273 0.018
coagulation GO:0050817 28 0.018
protein maturation GO:0051604 68 0.018
positive regulation of dna recombination GO:0045911 1 0.018
regulation of reactive oxygen species metabolic process GO:2000377 26 0.017
organic hydroxy compound transport GO:0015850 77 0.017
intracellular transport GO:0046907 185 0.017
organ morphogenesis GO:0009887 75 0.017
regulation of reactive oxygen species biosynthetic process GO:1903426 5 0.017
negative regulation of programmed cell death GO:0043069 183 0.017
hormone secretion GO:0046879 115 0.017
single organism intracellular transport GO:1902582 166 0.017
cellular response to abiotic stimulus GO:0071214 85 0.017
cellular response to cytokine stimulus GO:0071345 127 0.017
pyruvate metabolic process GO:0006090 27 0.017
regulation of kinase activity GO:0043549 117 0.016
positive regulation of isotype switching GO:0045830 1 0.016
positive regulation of transferase activity GO:0051347 81 0.016
cellular divalent inorganic cation homeostasis GO:0072503 162 0.016
reactive nitrogen species metabolic process GO:2001057 1 0.016
central nervous system development GO:0007417 311 0.016
lipid localization GO:0010876 62 0.016
reactive oxygen species biosynthetic process GO:1903409 8 0.016
somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 2 0.016
nucleotide biosynthetic process GO:0009165 98 0.016
cellular macromolecule localization GO:0070727 122 0.016
positive regulation of apoptotic process GO:0043065 154 0.016
heart morphogenesis GO:0003007 3 0.016
cellular ion homeostasis GO:0006873 184 0.016
positive regulation of protein kinase activity GO:0045860 73 0.016
regulation of transmembrane transport GO:0034762 122 0.016
g protein coupled receptor signaling pathway GO:0007186 242 0.016
regulation of programmed cell death GO:0043067 341 0.016
response to corticosteroid GO:0031960 235 0.015
multi organism reproductive process GO:0044703 262 0.015
regulation of locomotion GO:0040012 148 0.015
camp metabolic process GO:0046058 63 0.015
glycosyl compound metabolic process GO:1901657 182 0.015
multicellular organismal reproductive process GO:0048609 233 0.015
sorbitol metabolic process GO:0006060 1 0.015
response to monosaccharide GO:0034284 159 0.015
alditol metabolic process GO:0019400 4 0.015
cellular response to acid chemical GO:0071229 75 0.015
signal transduction by phosphorylation GO:0023014 144 0.015
icosanoid biosynthetic process GO:0046456 18 0.015
regulation of dna metabolic process GO:0051052 60 0.015
regulation of secretion by cell GO:1903530 208 0.015
regulation of response to external stimulus GO:0032101 106 0.015
regulation of telomerase activity GO:0051972 2 0.015
positive regulation of hormone secretion GO:0046887 65 0.015
regulation of calcineurin nfat signaling cascade GO:0070884 3 0.015
negative regulation of cellular metabolic process GO:0031324 281 0.015
inorganic ion transmembrane transport GO:0098660 229 0.015
tube development GO:0035295 89 0.015
regeneration GO:0031099 163 0.015
regulation of homeostatic process GO:0032844 101 0.014
regulation of nervous system development GO:0051960 264 0.014
cellular homeostasis GO:0019725 252 0.014
oxidation reduction process GO:0055114 304 0.014
negative regulation of apoptotic process GO:0043066 181 0.014
cellular response to hormone stimulus GO:0032870 247 0.014
secretion GO:0046903 307 0.014
reproductive structure development GO:0048608 128 0.014
mapk cascade GO:0000165 140 0.014
regulation of g protein coupled receptor protein signaling pathway GO:0008277 28 0.014
regulation of cellular localization GO:0060341 263 0.014
cellular chemical homeostasis GO:0055082 247 0.014
linoleic acid metabolic process GO:0043651 4 0.014
cellular response to oxygen levels GO:0071453 60 0.014
peptide transport GO:0015833 97 0.014
lipid storage GO:0019915 1 0.014
response to cytokine GO:0034097 215 0.014
metal ion homeostasis GO:0055065 186 0.014
intestinal absorption GO:0050892 3 0.014
purine ribonucleotide metabolic process GO:0009150 227 0.014
potassium ion transport GO:0006813 97 0.013
leukocyte cell cell adhesion GO:0007159 4 0.013
maintenance of location GO:0051235 17 0.013
nucleoside metabolic process GO:0009116 179 0.013
immunoglobulin mediated immune response GO:0016064 4 0.013
aging GO:0007568 241 0.013
wound healing GO:0042060 122 0.013
negative regulation of cell death GO:0060548 229 0.013
ribonucleotide metabolic process GO:0009259 231 0.013
small molecule catabolic process GO:0044282 59 0.013
leukotriene biosynthetic process GO:0019370 3 0.013
response to hypoxia GO:0001666 231 0.013
regulation of signal transduction GO:0009966 318 0.013
muscle system process GO:0003012 115 0.013
regulation of membrane potential GO:0042391 110 0.013
multicellular organism growth GO:0035264 1 0.013
negative regulation of macromolecule metabolic process GO:0010605 260 0.013
learning or memory GO:0007611 90 0.013
actin filament based movement GO:0030048 16 0.013
regulation of neuron projection development GO:0010975 161 0.013
regulation of intracellular signal transduction GO:1902531 218 0.013
regulation of hormone levels GO:0010817 187 0.013
regulation of endocytosis GO:0030100 42 0.013
blood circulation GO:0008015 183 0.013
somatic recombination of immunoglobulin genes involved in immune response GO:0002204 1 0.013
regulation of cytokine biosynthetic process GO:0042035 3 0.012
gland development GO:0048732 155 0.012
regulation of establishment of protein localization GO:0070201 69 0.012
sterol catabolic process GO:0016127 1 0.012
endocytosis GO:0006897 84 0.012
positive regulation of b cell mediated immunity GO:0002714 2 0.012
cellular protein localization GO:0034613 122 0.012
response to estrogen GO:0043627 232 0.012
purine containing compound metabolic process GO:0072521 253 0.012
negative regulation of transcription regulatory region dna binding GO:2000678 2 0.012
positive regulation of transcription dna templated GO:0045893 197 0.012
inflammatory response GO:0006954 150 0.012
regulation of potassium ion transport GO:0043266 29 0.012
somatic cell dna recombination GO:0016444 2 0.012
developmental growth GO:0048589 100 0.012
ion transmembrane transport GO:0034220 365 0.012
sequestering of triglyceride GO:0030730 1 0.012
regulation of cellular component movement GO:0051270 150 0.012
regulation of cell development GO:0060284 263 0.012
sex differentiation GO:0007548 113 0.012
positive regulation of rna biosynthetic process GO:1902680 197 0.012
regulation of protein localization GO:0032880 81 0.012
regulation of phagocytosis engulfment GO:0060099 4 0.012
regulation of fat cell differentiation GO:0045598 3 0.012
actin filament based process GO:0030029 86 0.012
response to mechanical stimulus GO:0009612 134 0.011
negative regulation of gene expression GO:0010629 199 0.011
regulation of cell motility GO:2000145 131 0.011
regulation of secretion GO:0051046 224 0.011
leukocyte activation GO:0045321 76 0.011
nucleoside phosphate biosynthetic process GO:1901293 102 0.011
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.011
sequestering of metal ion GO:0051238 9 0.011
negative regulation of molecular function GO:0044092 133 0.011
positive regulation of gene expression GO:0010628 244 0.011
lipid oxidation GO:0034440 30 0.011
regulation of smooth muscle cell proliferation GO:0048660 75 0.011
regulation of anatomical structure size GO:0090066 135 0.011
sulfur compound metabolic process GO:0006790 70 0.011
ribose phosphate metabolic process GO:0019693 235 0.011
reproductive system development GO:0061458 128 0.011
developmental process involved in reproduction GO:0003006 159 0.011
organic cyclic compound catabolic process GO:1901361 175 0.011
fatty acid biosynthetic process GO:0006633 33 0.011
negative regulation of response to biotic stimulus GO:0002832 4 0.011
positive regulation of cell projection organization GO:0031346 111 0.011
neurological system process GO:0050877 219 0.011
purine nucleotide metabolic process GO:0006163 229 0.011
dephosphorylation GO:0016311 98 0.011
response to decreased oxygen levels GO:0036293 237 0.011
regulation of immune response GO:0050776 55 0.011
rhythmic process GO:0048511 156 0.011
sorbitol biosynthetic process GO:0006061 1 0.011
organophosphate catabolic process GO:0046434 148 0.011
chromosome segregation GO:0007059 2 0.011
negative regulation of cellular protein metabolic process GO:0032269 106 0.011
cell cycle checkpoint GO:0000075 2 0.011
ras protein signal transduction GO:0007265 29 0.011
heterocycle catabolic process GO:0046700 167 0.011
monocarboxylic acid biosynthetic process GO:0072330 48 0.011
peptidyl tyrosine modification GO:0018212 72 0.011
salivary gland development GO:0007431 3 0.011
positive regulation of lipid catabolic process GO:0050996 4 0.011
response to other organism GO:0051707 220 0.011
nicotinamide nucleotide metabolic process GO:0046496 28 0.011
regulation of lipid biosynthetic process GO:0046890 38 0.011
negative regulation of collagen biosynthetic process GO:0032966 4 0.011
positive regulation of cytokine biosynthetic process GO:0042108 1 0.011
detection of chemical stimulus involved in sensory perception of bitter taste GO:0001580 4 0.010
cell morphogenesis GO:0000902 142 0.010
carbohydrate catabolic process GO:0016052 40 0.010
dna recombination GO:0006310 3 0.010
response to insulin GO:0032868 133 0.010
cellular cation homeostasis GO:0030003 180 0.010
gonad development GO:0008406 104 0.010
localization of cell GO:0051674 202 0.010
vitamin d receptor signaling pathway GO:0070561 1 0.010
cellular calcium ion homeostasis GO:0006874 160 0.010
positive regulation of secretion by cell GO:1903532 128 0.010
small gtpase mediated signal transduction GO:0007264 36 0.010
regulation of immunoglobulin production GO:0002637 4 0.010
defense response GO:0006952 194 0.010
positive regulation of neuron projection development GO:0010976 99 0.010
coenzyme biosynthetic process GO:0009108 22 0.010
negative regulation of pancreatic stellate cell proliferation GO:2000230 1 0.010
multicellular organismal homeostasis GO:0048871 49 0.010

Bche disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.016
nutrition disease DOID:374 0 0.016
acquired metabolic disease DOID:0060158 0 0.016
disease of anatomical entity DOID:7 0 0.014
nervous system disease DOID:863 0 0.014
central nervous system disease DOID:331 0 0.012
obesity DOID:9970 0 0.012
overnutrition DOID:654 0 0.012
musculoskeletal system disease DOID:17 0 0.011